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Illumina Body Map 2: averaged replicates
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Results for SOX14
Z-value: 1.61
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Transcription factors associated with SOX14
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| SOX14 | hg19_v2_chr3_+_137483579_137483579 | -0.11 | 5.5e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr11_+_62186498 Show fit | 4.20 |
ENST00000278282.2
|
secretoglobin, family 1A, member 1 (uteroglobin) |
|
| chr5_-_180018540 Show fit | 2.79 |
ENST00000292641.3
|
secretoglobin, family 3A, member 1 |
|
| chr12_-_52887034 Show fit | 2.47 |
ENST00000330722.6
|
keratin 6A |
|
| chr14_-_106478603 Show fit | 2.26 |
ENST00000390596.2
|
immunoglobulin heavy variable 4-4 |
|
| chr12_+_8666126 Show fit | 2.13 |
ENST00000299665.2
|
C-type lectin domain family 4, member D |
|
| chr2_-_89161064 Show fit | 2.10 |
ENST00000390241.2
|
immunoglobulin kappa joining 2 |
|
| chr2_-_89160425 Show fit | 2.09 |
ENST00000390239.2
|
immunoglobulin kappa joining 4 |
|
| chr2_-_89160770 Show fit | 2.00 |
ENST00000390240.2
|
immunoglobulin kappa joining 3 |
|
| chr11_-_102595681 Show fit | 1.95 |
ENST00000236826.3
|
matrix metallopeptidase 8 (neutrophil collagenase) |
|
| chr11_-_102595512 Show fit | 1.85 |
ENST00000438475.2
|
matrix metallopeptidase 8 (neutrophil collagenase) |
Network of associatons between targets according to the STRING database.
First level regulatory network of SOX14
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.8 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 0.0 | 4.6 | GO:0030574 | collagen catabolic process(GO:0030574) |
| 0.7 | 4.2 | GO:0010193 | response to ozone(GO:0010193) |
| 0.2 | 4.2 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
| 0.2 | 3.8 | GO:0070050 | neuron cellular homeostasis(GO:0070050) |
| 0.0 | 2.9 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
| 0.1 | 2.8 | GO:1901741 | positive regulation of myoblast fusion(GO:1901741) |
| 0.6 | 2.5 | GO:0051710 | cytolysis by symbiont of host cells(GO:0001897) regulation of cytolysis in other organism(GO:0051710) |
| 0.0 | 2.3 | GO:0006910 | phagocytosis, recognition(GO:0006910) |
| 0.7 | 2.2 | GO:1990575 | mitochondrial L-ornithine transmembrane transport(GO:1990575) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.3 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.0 | 3.8 | GO:1904724 | tertiary granule lumen(GO:1904724) |
| 0.0 | 3.2 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.1 | 3.1 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 0.0 | 2.7 | GO:0070821 | tertiary granule membrane(GO:0070821) |
| 0.0 | 2.3 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
| 0.0 | 2.3 | GO:0045095 | keratin filament(GO:0045095) |
| 0.3 | 2.2 | GO:0032133 | chromosome passenger complex(GO:0032133) |
| 0.2 | 2.2 | GO:0042612 | MHC class I protein complex(GO:0042612) |
| 0.1 | 2.2 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.4 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.0 | 4.4 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.4 | 4.2 | GO:0019834 | phospholipase A2 inhibitor activity(GO:0019834) |
| 0.3 | 4.2 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 0.0 | 3.1 | GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980) |
| 0.6 | 2.9 | GO:0004556 | alpha-amylase activity(GO:0004556) |
| 0.0 | 2.7 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.0 | 2.6 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.0 | 2.3 | GO:0004114 | 3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114) |
| 0.0 | 2.3 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.2 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.0 | 3.7 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 3.1 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.0 | 2.4 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.0 | 2.1 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.0 | 2.0 | PID CD40 PATHWAY | CD40/CD40L signaling |
| 0.0 | 1.7 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
| 0.0 | 1.6 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.0 | 1.1 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.0 | 1.0 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 6.1 | REACTOME DIGESTION OF DIETARY CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |
| 0.1 | 4.3 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.0 | 3.0 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.0 | 2.5 | REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
| 0.0 | 2.2 | REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 | Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 |
| 0.0 | 2.2 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.0 | 1.9 | REACTOME NOD1 2 SIGNALING PATHWAY | Genes involved in NOD1/2 Signaling Pathway |
| 0.0 | 1.9 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
| 0.1 | 1.8 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.2 | 1.7 | REACTOME ENDOSOMAL VACUOLAR PATHWAY | Genes involved in Endosomal/Vacuolar pathway |