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Illumina Body Map 2: averaged replicates

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Results for SOX18

Z-value: 1.43

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Transcription factors associated with SOX18

Gene Symbol Gene ID Gene Info
SOX18
ENSG00000203883.5 SRY-box transcription factor 18

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX18hg19_v2_chr20_-_62680984_62680999-0.251.7e-01Click!

Activity profile of SOX18 motif

Sorted Z-values of SOX18 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chrX_+_37850026 2.20 ENST00000341016.3
CXorf27
chromosome X open reading frame 27
chr1_-_95783809 2.13 ENST00000423410.1
RP4-586O15.1
RP4-586O15.1
chr14_+_22538811 2.03 ENST00000390450.3
TRAV22
T cell receptor alpha variable 22
chr2_+_79252822 2.00 ENST00000272324.5
REG3G
regenerating islet-derived 3 gamma
chr11_+_60102304 1.99 ENST00000300182.4
MS4A6E
membrane-spanning 4-domains, subfamily A, member 6E
chr15_+_22382382 1.86 ENST00000328795.4
OR4N4
olfactory receptor, family 4, subfamily N, member 4
chrX_+_30261847 1.72 ENST00000378981.3
ENST00000397550.1
MAGEB1
melanoma antigen family B, 1
chr5_+_127039075 1.71 ENST00000514853.2
CTC-228N24.1
CTC-228N24.1
chr2_+_79252834 1.69 ENST00000409471.1
REG3G
regenerating islet-derived 3 gamma
chr2_+_79252804 1.68 ENST00000393897.2
REG3G
regenerating islet-derived 3 gamma
chr12_+_15475462 1.62 ENST00000543886.1
ENST00000348962.2
PTPRO
protein tyrosine phosphatase, receptor type, O
chr1_+_2938044 1.61 ENST00000378404.2
ACTRT2
actin-related protein T2
chr6_-_49989648 1.60 ENST00000393660.2
ENST00000371148.2
DEFB110
defensin, beta 110 locus
chr7_-_142120321 1.43 ENST00000390377.1
TRBV7-7
T cell receptor beta variable 7-7
chr1_+_34326076 1.42 ENST00000519684.1
ENST00000522796.1
HMGB4
high mobility group box 4
chr12_-_10562356 1.40 ENST00000309384.1
KLRC4
killer cell lectin-like receptor subfamily C, member 4
chr8_+_62737875 1.38 ENST00000523042.1
ENST00000518593.1
ENST00000519452.1
ENST00000519967.1
RP11-705O24.1
RP11-705O24.1
chr5_+_147648393 1.37 ENST00000511106.1
ENST00000398450.4
SPINK13
serine peptidase inhibitor, Kazal type 13 (putative)
chr19_+_48497901 1.36 ENST00000339841.2
ELSPBP1
epididymal sperm binding protein 1
chr19_-_6501778 1.33 ENST00000596291.1
TUBB4A
tubulin, beta 4A class IVa
chr5_-_136834982 1.30 ENST00000510689.1
ENST00000394945.1
SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr3_+_94657016 1.24 ENST00000462219.1
LINC00879
long intergenic non-protein coding RNA 879
chr5_-_99870932 1.22 ENST00000504833.1
CTD-2001C12.1
CTD-2001C12.1
chr9_-_99064429 1.16 ENST00000375263.3
HSD17B3
hydroxysteroid (17-beta) dehydrogenase 3
chr14_+_22392209 1.16 ENST00000390440.2
TRAV14DV4
T cell receptor alpha variable 14/delta variable 4
chr12_-_10573149 1.15 ENST00000381904.2
ENST00000381903.2
ENST00000396439.2
KLRC3
killer cell lectin-like receptor subfamily C, member 3
chr7_-_121944491 1.14 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
FEZF1
FEZ family zinc finger 1
chr8_+_35649365 1.14 ENST00000437887.1
AC012215.1
Uncharacterized protein
chr13_+_32313658 1.13 ENST00000380314.1
ENST00000298386.2
RXFP2
relaxin/insulin-like family peptide receptor 2
chr10_-_8095412 1.11 ENST00000458727.1
ENST00000355358.1
RP11-379F12.3
GATA3-AS1
RP11-379F12.3
GATA3 antisense RNA 1
chr8_-_82443613 1.11 ENST00000360464.4
FABP12
fatty acid binding protein 12
chr17_-_39041479 1.08 ENST00000167588.3
KRT20
keratin 20
chr6_-_160679905 1.06 ENST00000366953.3
SLC22A2
solute carrier family 22 (organic cation transporter), member 2
chr2_+_241544834 1.05 ENST00000319838.5
ENST00000403859.1
ENST00000438013.2
GPR35
G protein-coupled receptor 35
chr6_+_123317116 1.04 ENST00000275162.5
CLVS2
clavesin 2
chr3_+_19189946 1.04 ENST00000328405.2
KCNH8
potassium voltage-gated channel, subfamily H (eag-related), member 8
chr9_-_99064386 1.02 ENST00000375262.2
HSD17B3
hydroxysteroid (17-beta) dehydrogenase 3
chrY_+_3447082 0.96 ENST00000321217.4
ENST00000559055.2
TGIF2LY
TGFB-induced factor homeobox 2-like, Y-linked
chr5_-_101834712 0.93 ENST00000506729.1
ENST00000389019.3
ENST00000379810.1
SLCO6A1
solute carrier organic anion transporter family, member 6A1
chr17_-_8661860 0.92 ENST00000328794.6
SPDYE4
speedy/RINGO cell cycle regulator family member E4
chr7_+_10000640 0.91 ENST00000451755.1
AC006373.1
AC006373.1
chr21_-_26797019 0.90 ENST00000440205.1
LINC00158
long intergenic non-protein coding RNA 158
chr3_+_111717600 0.89 ENST00000273368.4
TAGLN3
transgelin 3
chr7_-_122339162 0.89 ENST00000340112.2
RNF133
ring finger protein 133
chr11_+_59807748 0.87 ENST00000278855.2
ENST00000532905.1
PLAC1L
oocyte secreted protein 2
chr3_+_140947563 0.86 ENST00000505013.1
ACPL2
acid phosphatase-like 2
chr9_+_33240157 0.86 ENST00000379721.3
SPINK4
serine peptidase inhibitor, Kazal type 4
chr6_+_140175987 0.85 ENST00000414038.1
ENST00000431609.1
RP5-899B16.1
RP5-899B16.1
chr8_+_7397150 0.85 ENST00000533250.1
RP11-1118M6.1
proline rich 23 domain containing 1
chr5_-_101834617 0.85 ENST00000513675.1
ENST00000379807.3
SLCO6A1
solute carrier organic anion transporter family, member 6A1
chr5_-_146461027 0.85 ENST00000394410.2
ENST00000508267.1
ENST00000504198.1
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr12_+_110940111 0.84 ENST00000409778.3
RAD9B
RAD9 homolog B (S. pombe)
chr12_-_48963829 0.84 ENST00000301046.2
ENST00000549817.1
LALBA
lactalbumin, alpha-
chr4_-_57524061 0.83 ENST00000508121.1
HOPX
HOP homeobox
chr19_-_55453077 0.83 ENST00000328092.5
ENST00000590030.1
NLRP7
NLR family, pyrin domain containing 7
chr8_-_126963487 0.82 ENST00000518964.1
LINC00861
long intergenic non-protein coding RNA 861
chr7_-_142176790 0.82 ENST00000390369.2
TRBV7-4
T cell receptor beta variable 7-4 (gene/pseudogene)
chr1_-_156828810 0.82 ENST00000368195.3
INSRR
insulin receptor-related receptor
chr2_-_158345341 0.81 ENST00000435117.1
CYTIP
cytohesin 1 interacting protein
chr12_+_104697504 0.81 ENST00000527879.1
EID3
EP300 interacting inhibitor of differentiation 3
chr15_+_28624878 0.81 ENST00000450328.2
GOLGA8F
golgin A8 family, member F
chr6_-_110500826 0.79 ENST00000265601.3
ENST00000447287.1
ENST00000444391.1
WASF1
WAS protein family, member 1
chr13_-_84456527 0.78 ENST00000377084.2
SLITRK1
SLIT and NTRK-like family, member 1
chr12_-_7904201 0.77 ENST00000354629.5
CLEC4C
C-type lectin domain family 4, member C
chr3_+_68055366 0.77 ENST00000496687.1
FAM19A1
family with sequence similarity 19 (chemokine (C-C motif)-like), member A1
chrX_-_132095419 0.76 ENST00000370836.2
ENST00000521489.1
HS6ST2
heparan sulfate 6-O-sulfotransferase 2
chr11_+_41736067 0.76 ENST00000528720.1
RP11-375D13.2
RP11-375D13.2
chr1_+_228003394 0.74 ENST00000366757.3
PRSS38
protease, serine, 38
chr3_+_126911974 0.72 ENST00000398112.1
C3orf56
chromosome 3 open reading frame 56
chr6_-_30899924 0.72 ENST00000359086.3
SFTA2
surfactant associated 2
chr20_+_59654146 0.71 ENST00000441660.1
RP5-827L5.1
RP5-827L5.1
chr4_-_109541610 0.70 ENST00000510212.1
RPL34-AS1
RPL34 antisense RNA 1 (head to head)
chr12_-_111127551 0.69 ENST00000439744.2
ENST00000549442.1
HVCN1
hydrogen voltage-gated channel 1
chr2_+_217277271 0.69 ENST00000425815.1
SMARCAL1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
chr8_+_24151620 0.69 ENST00000437154.2
ADAM28
ADAM metallopeptidase domain 28
chr1_+_64669294 0.68 ENST00000371077.5
UBE2U
ubiquitin-conjugating enzyme E2U (putative)
chr2_-_47382442 0.68 ENST00000445927.2
C2orf61
chromosome 2 open reading frame 61
chr1_+_160051319 0.68 ENST00000368088.3
KCNJ9
potassium inwardly-rectifying channel, subfamily J, member 9
chr12_-_70093111 0.67 ENST00000548658.1
ENST00000476098.1
ENST00000331471.4
ENST00000393365.1
BEST3
bestrophin 3
chr14_+_22217447 0.66 ENST00000390427.3
TRAV5
T cell receptor alpha variable 5
chr20_+_31499459 0.66 ENST00000439060.1
EFCAB8
EF-hand calcium binding domain 8
chr8_-_7638935 0.66 ENST00000528972.1
AC084121.16
proline rich 23 domain containing 2
chr5_-_43515125 0.66 ENST00000509489.1
C5orf34
chromosome 5 open reading frame 34
chr12_-_70093065 0.65 ENST00000553096.1
BEST3
bestrophin 3
chr11_+_73360024 0.65 ENST00000540431.1
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr1_+_73771844 0.63 ENST00000440762.1
ENST00000444827.1
ENST00000415686.1
ENST00000411903.1
RP4-598G3.1
RP4-598G3.1
chr6_-_110500905 0.63 ENST00000392587.2
WASF1
WAS protein family, member 1
chr5_-_55412774 0.61 ENST00000434982.2
ANKRD55
ankyrin repeat domain 55
chr4_-_123377880 0.61 ENST00000226730.4
IL2
interleukin 2
chr19_-_42192189 0.60 ENST00000401731.1
ENST00000338196.4
ENST00000006724.3
CEACAM7
carcinoembryonic antigen-related cell adhesion molecule 7
chr3_+_108541545 0.60 ENST00000295756.6
TRAT1
T cell receptor associated transmembrane adaptor 1
chr11_+_1092184 0.59 ENST00000361558.6
MUC2
mucin 2, oligomeric mucus/gel-forming
chr12_-_70093190 0.59 ENST00000330891.5
BEST3
bestrophin 3
chr11_+_73358690 0.58 ENST00000545798.1
ENST00000539157.1
ENST00000546251.1
ENST00000535582.1
ENST00000538227.1
ENST00000543524.1
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr2_-_158345462 0.58 ENST00000439355.1
ENST00000540637.1
CYTIP
cytohesin 1 interacting protein
chr15_-_21071643 0.58 ENST00000454856.4
POTEB2
POTE ankyrin domain family, member B2
chr12_-_8088773 0.58 ENST00000544291.1
SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr15_-_22082822 0.57 ENST00000439682.1
POTEB
POTE ankyrin domain family, member B
chr12_+_110940005 0.57 ENST00000409246.1
ENST00000392672.4
ENST00000409300.1
ENST00000409425.1
RAD9B
RAD9 homolog B (S. pombe)
chr18_+_73971121 0.57 ENST00000577797.1
RP11-94B19.4
Uncharacterized protein
chr1_+_209929494 0.56 ENST00000367026.3
TRAF3IP3
TRAF3 interacting protein 3
chr3_+_35721182 0.54 ENST00000413378.1
ENST00000417925.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr1_+_209929377 0.53 ENST00000400959.3
ENST00000367025.3
TRAF3IP3
TRAF3 interacting protein 3
chr11_+_73359936 0.53 ENST00000542389.1
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr9_+_33638033 0.53 ENST00000390389.3
TRBV23OR9-2
T cell receptor beta variable 23/OR9-2 (non-functional)
chrX_-_101726732 0.53 ENST00000457521.2
ENST00000412230.2
ENST00000453326.2
NXF2B
TCP11X2
nuclear RNA export factor 2B
t-complex 11 family, X-linked 2
chr3_-_112693759 0.52 ENST00000440122.2
ENST00000490004.1
CD200R1
CD200 receptor 1
chr19_-_39805976 0.52 ENST00000248668.4
LRFN1
leucine rich repeat and fibronectin type III domain containing 1
chr2_-_220197351 0.52 ENST00000392083.1
RESP18
regulated endocrine-specific protein 18
chr12_-_11244912 0.52 ENST00000531678.1
TAS2R43
taste receptor, type 2, member 43
chr11_-_56000737 0.51 ENST00000313264.4
OR5T2
olfactory receptor, family 5, subfamily T, member 2
chr6_+_29427548 0.51 ENST00000377132.1
OR2H1
olfactory receptor, family 2, subfamily H, member 1
chrX_+_101470280 0.51 ENST00000395088.2
ENST00000330252.5
ENST00000333110.5
NXF2
TCP11X1
nuclear RNA export factor 2
t-complex 11 family, X-linked 1
chr3_+_35721106 0.51 ENST00000474696.1
ENST00000412048.1
ENST00000396482.2
ENST00000432682.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr2_-_49381572 0.50 ENST00000454032.1
ENST00000304421.4
FSHR
follicle stimulating hormone receptor
chr14_+_22564294 0.50 ENST00000390452.2
TRDV1
T cell receptor delta variable 1
chr9_+_33629119 0.48 ENST00000331828.4
TRBV21OR9-2
T cell receptor beta variable 21/OR9-2 (pseudogene)
chr3_+_187420101 0.48 ENST00000449623.1
ENST00000437407.1
RP11-211G3.3
Uncharacterized protein
chr12_-_71148413 0.48 ENST00000440835.2
ENST00000549308.1
ENST00000550661.1
PTPRR
protein tyrosine phosphatase, receptor type, R
chr1_+_55271736 0.47 ENST00000358193.3
ENST00000371273.3
C1orf177
chromosome 1 open reading frame 177
chr2_-_211168332 0.47 ENST00000341685.4
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr1_+_248185250 0.47 ENST00000355281.1
OR2L5
olfactory receptor, family 2, subfamily L, member 5
chr1_-_153513170 0.47 ENST00000368717.2
S100A5
S100 calcium binding protein A5
chr17_-_28661065 0.47 ENST00000328886.4
ENST00000538566.2
TMIGD1
transmembrane and immunoglobulin domain containing 1
chr1_-_114430169 0.46 ENST00000393316.3
BCL2L15
BCL2-like 15
chr7_+_12727250 0.46 ENST00000404894.1
ARL4A
ADP-ribosylation factor-like 4A
chr12_+_8666126 0.46 ENST00000299665.2
CLEC4D
C-type lectin domain family 4, member D
chr17_+_56315787 0.46 ENST00000262290.4
ENST00000421678.2
LPO
lactoperoxidase
chr6_-_128222103 0.46 ENST00000434358.1
ENST00000543064.1
ENST00000368248.2
THEMIS
thymocyte selection associated
chr7_-_93204033 0.45 ENST00000359558.2
ENST00000360249.4
ENST00000426151.1
CALCR
calcitonin receptor
chr10_-_85985294 0.45 ENST00000538192.1
LRIT2
leucine-rich repeat, immunoglobulin-like and transmembrane domains 2
chr3_-_120003941 0.45 ENST00000464295.1
GPR156
G protein-coupled receptor 156
chr22_+_27017921 0.45 ENST00000354760.3
CRYBA4
crystallin, beta A4
chr14_-_22938665 0.45 ENST00000535880.2
TRDV3
T cell receptor delta variable 3
chr1_+_55446465 0.45 ENST00000371268.3
TMEM61
transmembrane protein 61
chr5_-_99870890 0.45 ENST00000499025.1
CTD-2001C12.1
CTD-2001C12.1
chrX_-_110507098 0.45 ENST00000541758.1
CAPN6
calpain 6
chr17_+_68071389 0.45 ENST00000283936.1
ENST00000392671.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr19_+_8117636 0.45 ENST00000253451.4
ENST00000315626.4
CCL25
chemokine (C-C motif) ligand 25
chr8_-_4852494 0.44 ENST00000520002.1
ENST00000602557.1
CSMD1
CUB and Sushi multiple domains 1
chr17_+_68071458 0.44 ENST00000589377.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr12_+_85430110 0.44 ENST00000393212.3
ENST00000393217.2
LRRIQ1
leucine-rich repeats and IQ motif containing 1
chr1_+_66258846 0.44 ENST00000341517.4
PDE4B
phosphodiesterase 4B, cAMP-specific
chr21_+_30671690 0.44 ENST00000399921.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr5_-_43515231 0.44 ENST00000306862.2
C5orf34
chromosome 5 open reading frame 34
chrX_-_70329118 0.43 ENST00000374188.3
IL2RG
interleukin 2 receptor, gamma
chr19_-_43382142 0.43 ENST00000597058.1
PSG1
pregnancy specific beta-1-glycoprotein 1
chr3_+_160394940 0.43 ENST00000320767.2
ARL14
ADP-ribosylation factor-like 14
chr4_+_109541772 0.43 ENST00000506397.1
ENST00000394668.2
RPL34
ribosomal protein L34
chr11_+_123986069 0.42 ENST00000456829.2
ENST00000361352.5
ENST00000449321.1
ENST00000392748.1
ENST00000360334.4
ENST00000392744.4
VWA5A
von Willebrand factor A domain containing 5A
chr9_+_137987825 0.42 ENST00000545657.1
OLFM1
olfactomedin 1
chr8_-_94147664 0.41 ENST00000522116.1
C8orf87
chromosome 8 open reading frame 87
chr12_-_75603482 0.41 ENST00000341669.3
ENST00000298972.1
ENST00000350228.2
KCNC2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr2_+_74881355 0.41 ENST00000357877.2
SEMA4F
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
chr14_+_24970800 0.41 ENST00000555109.1
RP11-80A15.1
Uncharacterized protein
chr3_-_112693865 0.41 ENST00000471858.1
ENST00000295863.4
ENST00000308611.3
CD200R1
CD200 receptor 1
chr19_+_4402659 0.41 ENST00000301280.5
ENST00000585854.1
CHAF1A
chromatin assembly factor 1, subunit A (p150)
chrX_-_15620192 0.41 ENST00000427411.1
ACE2
angiotensin I converting enzyme 2
chr11_-_55371874 0.40 ENST00000302231.4
OR4C11
olfactory receptor, family 4, subfamily C, member 11
chr11_-_131533462 0.39 ENST00000416725.1
AP003039.3
AP003039.3
chr11_-_85397167 0.39 ENST00000316398.3
CCDC89
coiled-coil domain containing 89
chr2_-_165811756 0.39 ENST00000409662.1
SLC38A11
solute carrier family 38, member 11
chr19_+_33571786 0.39 ENST00000170564.2
GPATCH1
G patch domain containing 1
chr4_-_109541539 0.39 ENST00000509984.1
ENST00000507248.1
ENST00000506795.1
RPL34-AS1
RPL34 antisense RNA 1 (head to head)
chr22_+_20850171 0.39 ENST00000445987.1
MED15
mediator complex subunit 15
chr2_-_49381646 0.39 ENST00000346173.3
ENST00000406846.2
FSHR
follicle stimulating hormone receptor
chr12_-_49999417 0.39 ENST00000257894.2
FAM186B
family with sequence similarity 186, member B
chr18_-_5396271 0.39 ENST00000579951.1
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr10_-_85985282 0.39 ENST00000372113.4
LRIT2
leucine-rich repeat, immunoglobulin-like and transmembrane domains 2
chr19_-_7040190 0.38 ENST00000381394.4
MBD3L4
methyl-CpG binding domain protein 3-like 4
chr3_+_35721130 0.38 ENST00000432450.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr12_-_67197760 0.38 ENST00000539540.1
ENST00000540433.1
ENST00000541947.1
ENST00000538373.1
GRIP1
glutamate receptor interacting protein 1
chr1_+_152483278 0.38 ENST00000334269.2
LCE5A
late cornified envelope 5A
chr16_-_68034470 0.38 ENST00000412757.2
DPEP2
dipeptidase 2
chr11_+_18230685 0.37 ENST00000340135.3
ENST00000534640.1
RP11-113D6.10
Putative mitochondrial carrier protein LOC494141
chr4_+_26322987 0.37 ENST00000505958.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr10_-_105992059 0.37 ENST00000369720.1
ENST00000369719.1
ENST00000357060.3
ENST00000428666.1
ENST00000278064.2
WDR96
WD repeat domain 96
chr11_+_20620946 0.37 ENST00000525748.1
SLC6A5
solute carrier family 6 (neurotransmitter transporter), member 5
chr12_-_68647281 0.37 ENST00000328087.4
ENST00000538666.1
IL22
interleukin 22
chr1_-_155881156 0.35 ENST00000539040.1
ENST00000368323.3
RIT1
Ras-like without CAAX 1
chr12_-_71148357 0.35 ENST00000378778.1
PTPRR
protein tyrosine phosphatase, receptor type, R
chr5_-_78808617 0.35 ENST00000282260.6
ENST00000508576.1
ENST00000535690.1
HOMER1
homer homolog 1 (Drosophila)
chr3_+_102153859 0.35 ENST00000306176.1
ENST00000466937.1
ZPLD1
zona pellucida-like domain containing 1
chr2_-_47382414 0.35 ENST00000294947.2
C2orf61
chromosome 2 open reading frame 61
chr6_-_27880174 0.35 ENST00000303324.2
OR2B2
olfactory receptor, family 2, subfamily B, member 2
chr6_-_33754778 0.34 ENST00000508327.1
ENST00000513701.1
LEMD2
LEM domain containing 2
chr17_-_76719638 0.34 ENST00000587308.1
CYTH1
cytohesin 1
chr19_+_8117881 0.34 ENST00000390669.3
CCL25
chemokine (C-C motif) ligand 25
chr9_-_127533519 0.34 ENST00000487099.2
ENST00000344523.4
ENST00000373584.3
NR6A1
nuclear receptor subfamily 6, group A, member 1
chr2_+_217277137 0.34 ENST00000430374.1
ENST00000357276.4
ENST00000444508.1
SMARCAL1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
chr17_+_25799008 0.34 ENST00000583370.1
ENST00000398988.3
ENST00000268763.6
KSR1
kinase suppressor of ras 1
chr4_+_109541722 0.34 ENST00000394667.3
ENST00000502534.1
RPL34
ribosomal protein L34
chr2_+_74881398 0.33 ENST00000339773.5
ENST00000434486.1
SEMA4F
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
chr12_-_8088871 0.33 ENST00000075120.7
SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr7_+_35756066 0.33 ENST00000449644.1
AC018647.3
AC018647.3
chr1_+_247768856 0.33 ENST00000320002.2
OR2G3
olfactory receptor, family 2, subfamily G, member 3
chr17_+_56316054 0.33 ENST00000581008.1
LPO
lactoperoxidase
chr8_-_4852218 0.32 ENST00000400186.3
ENST00000602723.1
CSMD1
CUB and Sushi multiple domains 1
chr12_-_75603643 0.32 ENST00000549446.1
KCNC2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr19_+_7030589 0.32 ENST00000329753.5
MBD3L5
methyl-CpG binding domain protein 3-like 5

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX18

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.4 GO:0044278 cell wall disruption in other organism(GO:0044278)
0.5 1.6 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.4 1.1 GO:0018969 thiocyanate metabolic process(GO:0018969)
0.3 1.0 GO:0044727 DNA demethylation of male pronucleus(GO:0044727)
0.3 0.8 GO:0005989 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.2 1.4 GO:0060467 negative regulation of fertilization(GO:0060467)
0.2 0.9 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.2 0.9 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.2 0.8 GO:0071469 cellular response to alkaline pH(GO:0071469)
0.2 2.2 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.2 1.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.2 1.0 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.2 0.6 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.2 1.2 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.1 0.8 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1 0.8 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.8 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 1.4 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 1.0 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 0.3 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.1 0.4 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 0.4 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 1.3 GO:0000733 DNA strand renaturation(GO:0000733)
0.1 0.4 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.1 1.1 GO:1901374 acetate ester transport(GO:1901374)
0.1 0.6 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.3 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.1 0.4 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.1 1.4 GO:0000076 DNA replication checkpoint(GO:0000076) intra-S DNA damage checkpoint(GO:0031573)
0.1 0.4 GO:1905068 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.2 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.5 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 1.3 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.4 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.3 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.5 GO:0001701 in utero embryonic development(GO:0001701)
0.0 0.2 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 1.3 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.4 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:1900276 regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.0 0.3 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 1.4 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:0060796 regulation of transcription involved in primary germ layer cell fate commitment(GO:0060796)
0.0 1.8 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.3 GO:0097240 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.4 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.8 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.4 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.3 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 2.8 GO:0006968 cellular defense response(GO:0006968)
0.0 0.8 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.5 GO:0043383 negative T cell selection(GO:0043383)
0.0 0.5 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 6.3 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.2 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.7 GO:0071467 cellular response to pH(GO:0071467)
0.0 1.6 GO:0010107 potassium ion import(GO:0010107)
0.0 0.2 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.7 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.6 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.2 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.0 0.9 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.1 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.5 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 1.1 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.2 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.7 GO:0001556 oocyte maturation(GO:0001556)
0.0 1.5 GO:0007602 phototransduction(GO:0007602)
0.0 0.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.7 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.1 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 1.9 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.0 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.0 0.2 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.0 1.0 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.2 GO:0000338 protein deneddylation(GO:0000338)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0042585 germinal vesicle(GO:0042585)
0.2 0.6 GO:0070703 inner mucus layer(GO:0070702) outer mucus layer(GO:0070703)
0.2 1.4 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 0.4 GO:0033186 CAF-1 complex(GO:0033186)
0.1 1.3 GO:0033269 internode region of axon(GO:0033269)
0.1 0.8 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 1.4 GO:0031209 SCAR complex(GO:0031209)
0.1 0.5 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 0.5 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.1 1.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 0.7 GO:0033503 HULC complex(GO:0033503)
0.1 0.3 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0035101 FACT complex(GO:0035101)
0.0 0.4 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.1 GO:0039714 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.0 1.3 GO:0033268 node of Ranvier(GO:0033268)
0.0 1.6 GO:0030673 axolemma(GO:0030673)
0.0 0.5 GO:0001741 XY body(GO:0001741)
0.0 0.1 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 2.1 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 2.0 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.3 GO:0033391 chromatoid body(GO:0033391)
0.0 0.6 GO:0042101 T cell receptor complex(GO:0042101)
0.0 1.6 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.2 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 1.6 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.1 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.3 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 1.0 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.4 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.5 GO:0005859 muscle myosin complex(GO:0005859)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0036393 thiocyanate peroxidase activity(GO:0036393)
0.3 2.2 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.3 5.4 GO:0042834 peptidoglycan binding(GO:0042834)
0.3 1.1 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.2 0.9 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.2 0.8 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.2 0.8 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.2 0.9 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.2 0.8 GO:0004461 lactose synthase activity(GO:0004461)
0.1 0.4 GO:0045518 interleukin-22 receptor binding(GO:0045518)
0.1 1.0 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 0.7 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 0.2 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.1 0.5 GO:0004948 calcitonin receptor activity(GO:0004948)
0.1 0.4 GO:0004913 interleukin-4 receptor activity(GO:0004913) interleukin-7 receptor activity(GO:0004917)
0.1 1.3 GO:0036310 annealing helicase activity(GO:0036310)
0.1 0.4 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 0.5 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.6 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 1.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 1.0 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 1.1 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 0.4 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 1.8 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.4 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.3 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 1.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.3 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 1.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.2 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 1.8 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.6 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.4 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.1 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.2 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.1 GO:0070012 oligopeptidase activity(GO:0070012)
0.0 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 6.3 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.8 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.3 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.4 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.9 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.4 GO:0000150 recombinase activity(GO:0000150)
0.0 0.3 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.4 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.1 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 1.4 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.4 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.7 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 2.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.9 GO:0005254 chloride channel activity(GO:0005254)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 7.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 2.0 PID ATR PATHWAY ATR signaling pathway
0.0 1.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.7 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.6 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.3 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.4 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 0.9 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 1.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 1.6 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 1.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 2.2 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.9 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.6 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 5.6 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.8 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.9 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation