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Illumina Body Map 2: averaged replicates

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Results for SOX3_SOX2

Z-value: 3.64

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Transcription factors associated with SOX3_SOX2

Gene Symbol Gene ID Gene Info
ENSG00000134595.6 SRY-box transcription factor 3
ENSG00000181449.2 SRY-box transcription factor 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX2hg19_v2_chr3_+_181429704_1814297220.723.9e-06Click!
SOX3hg19_v2_chrX_-_139587225_1395872340.681.7e-05Click!

Activity profile of SOX3_SOX2 motif

Sorted Z-values of SOX3_SOX2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_39509070 10.90 ENST00000354668.4
ENST00000428261.1
ENST00000420739.1
ENST00000415443.1
ENST00000447324.1
ENST00000383754.3
myelin-associated oligodendrocyte basic protein
chrX_-_128788914 8.74 ENST00000429967.1
ENST00000307484.6
apelin
chrX_+_103028638 8.73 ENST00000434483.1
proteolipid protein 1
chr3_+_39509163 8.68 ENST00000436143.2
ENST00000441980.2
ENST00000311042.6
myelin-associated oligodendrocyte basic protein
chr6_-_127840336 8.53 ENST00000525778.1
SOGA family member 3
chr6_-_127840021 8.51 ENST00000465909.2
SOGA family member 3
chr18_-_74728998 7.72 ENST00000359645.3
ENST00000397875.3
ENST00000397869.3
ENST00000578193.1
ENST00000578873.1
ENST00000397866.4
ENST00000528160.1
ENST00000527041.1
ENST00000526111.1
ENST00000397865.5
ENST00000382582.3
myelin basic protein
chr15_+_80696666 7.62 ENST00000303329.4
aryl-hydrocarbon receptor nuclear translocator 2
chr2_-_158182410 7.38 ENST00000419116.2
ENST00000410096.1
ermin, ERM-like protein
chr9_+_103235365 7.31 ENST00000374879.4
transmembrane protein with EGF-like and two follistatin-like domains 1
chr11_-_18813353 7.30 ENST00000358540.2
ENST00000396171.4
ENST00000396167.2
protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
chr5_+_94727048 7.22 ENST00000283357.5
family with sequence similarity 81, member B
chr2_-_158182322 7.18 ENST00000420719.2
ENST00000409216.1
ermin, ERM-like protein
chr6_+_123317116 7.14 ENST00000275162.5
clavesin 2
chrX_+_103029314 7.01 ENST00000429977.1
proteolipid protein 1
chr4_-_176733377 6.69 ENST00000505375.1
glycoprotein M6A
chr16_+_89989687 6.41 ENST00000315491.7
ENST00000555576.1
ENST00000554336.1
ENST00000553967.1
Tubulin beta-3 chain
chr19_+_1452188 6.41 ENST00000587149.1
adenomatosis polyposis coli 2
chr10_-_75351088 6.11 ENST00000451492.1
ENST00000413442.1
ubiquitin specific peptidase 54
chr1_-_26233423 6.01 ENST00000357865.2
stathmin 1
chr1_-_26232951 5.99 ENST00000426559.2
ENST00000455785.2
stathmin 1
chr13_-_25745857 5.75 ENST00000381853.3
APC membrane recruitment protein 2
chr8_+_80523962 5.69 ENST00000518491.1
stathmin-like 2
chr4_+_95916947 5.67 ENST00000506363.1
bone morphogenetic protein receptor, type IB
chr19_-_38720294 5.63 ENST00000412732.1
ENST00000456296.1
D4, zinc and double PHD fingers family 1
chr8_+_61969714 5.63 ENST00000522621.1
clavesin 1
chr1_+_203096831 5.54 ENST00000337894.4
adenosine A1 receptor
chr1_+_50571949 5.52 ENST00000357083.4
ELAV like neuron-specific RNA binding protein 4
chrX_-_139866723 5.51 ENST00000370532.2
cerebellar degeneration-related protein 1, 34kDa
chr4_-_5890145 5.47 ENST00000397890.2
collapsin response mediator protein 1
chr20_-_52645231 5.47 ENST00000448484.1
breast carcinoma amplified sequence 1
chr5_+_140593509 5.43 ENST00000341948.4
protocadherin beta 13
chr10_-_128359074 5.37 ENST00000544758.1
chromosome 10 open reading frame 90
chr20_+_42875935 5.29 ENST00000438466.1
ENST00000372952.3
ENST00000537864.1
ENST00000445952.1
ganglioside induced differentiation associated protein 1-like 1
chr5_-_16936340 5.29 ENST00000507288.1
ENST00000513610.1
myosin X
chrX_-_24665353 5.19 ENST00000379144.2
phosphate cytidylyltransferase 1, choline, beta
chr5_-_146435501 5.18 ENST00000336640.6
protein phosphatase 2, regulatory subunit B, beta
chr18_+_21718924 5.13 ENST00000399496.3
calcium binding tyrosine-(Y)-phosphorylation regulated
chr5_-_114515734 5.12 ENST00000514154.1
ENST00000282369.3
tripartite motif containing 36
chr18_-_31802282 5.11 ENST00000535475.1
nucleolar protein 4
chrX_+_84499081 5.09 ENST00000276123.3
zinc finger protein 711
chr17_+_7608511 5.06 ENST00000226091.2
ephrin-B3
chr19_+_18726786 4.94 ENST00000594709.1
transmembrane protein 59-like
chr1_+_156589198 4.84 ENST00000456112.1
hyaluronan and proteoglycan link protein 2
chr7_+_107110488 4.83 ENST00000304402.4
G protein-coupled receptor 22
chrX_+_84499038 4.79 ENST00000373165.3
zinc finger protein 711
chr5_-_146435694 4.77 ENST00000356826.3
protein phosphatase 2, regulatory subunit B, beta
chr1_-_26232522 4.74 ENST00000399728.1
stathmin 1
chr8_-_18871159 4.74 ENST00000327040.8
ENST00000440756.2
pleckstrin and Sec7 domain containing 3
chr21_+_41239243 4.73 ENST00000328619.5
Purkinje cell protein 4
chr15_+_84115868 4.73 ENST00000427482.2
SH3-domain GRB2-like 3
chr1_+_156589051 4.68 ENST00000255039.1
hyaluronan and proteoglycan link protein 2
chr17_-_37764128 4.64 ENST00000302584.4
neuronal differentiation 2
chr9_+_139874683 4.59 ENST00000444903.1
prostaglandin D2 synthase 21kDa (brain)
chrX_-_24665208 4.58 ENST00000356768.4
phosphate cytidylyltransferase 1, choline, beta
chr2_+_210444142 4.58 ENST00000360351.4
ENST00000361559.4
microtubule-associated protein 2
chr7_+_20370300 4.56 ENST00000537992.1
integrin, beta 8
chr1_+_151682909 4.50 ENST00000326413.3
ENST00000442233.2
regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1
Uncharacterized protein; cDNA FLJ36032 fis, clone TESTI2017069
chr1_+_240255166 4.44 ENST00000319653.9
formin 2
chr2_-_2334888 4.43 ENST00000428368.2
ENST00000399161.2
myelin transcription factor 1-like
chrX_+_84498989 4.39 ENST00000395402.1
zinc finger protein 711
chr9_-_73483958 4.38 ENST00000377101.1
ENST00000377106.1
ENST00000360823.2
ENST00000377105.1
transient receptor potential cation channel, subfamily M, member 3
chr8_-_21988558 4.37 ENST00000312841.8
hair growth associated
chr11_+_60691924 4.36 ENST00000544065.1
ENST00000453848.2
ENST00000005286.4
transmembrane protein 132A
chr1_+_150229554 4.35 ENST00000369111.4
carbonic anhydrase XIV
chr7_+_20370746 4.31 ENST00000222573.4
integrin, beta 8
chr8_-_22014339 4.28 ENST00000306317.2
leucine-rich repeat LGI family, member 3
chr19_-_38720354 4.27 ENST00000416611.1
D4, zinc and double PHD fingers family 1
chrX_-_13956497 4.24 ENST00000398361.3
glycoprotein M6B
chr5_-_146833803 4.22 ENST00000512722.1
dihydropyrimidinase-like 3
chr15_-_94614049 4.18 ENST00000556447.1
ENST00000555772.1
CTD-3049M7.1
chr15_+_101402041 4.15 ENST00000558475.1
ENST00000558641.1
ENST00000559673.1
RP11-66B24.1
chr5_+_169931249 4.13 ENST00000520740.1
Kv channel interacting protein 1
chr5_-_146435572 4.11 ENST00000394414.1
protein phosphatase 2, regulatory subunit B, beta
chr1_+_228337553 4.04 ENST00000366714.2
gap junction protein, gamma 2, 47kDa
chrX_-_138724677 4.03 ENST00000370573.4
ENST00000338585.6
ENST00000370576.4
MCF.2 cell line derived transforming sequence
chr7_+_154002527 4.03 ENST00000427557.1
dipeptidyl-peptidase 6
chr2_+_27070964 4.01 ENST00000288699.6
dihydropyrimidinase-like 5
chr5_-_146833485 3.99 ENST00000398514.3
dihydropyrimidinase-like 3
chr5_+_140480083 3.98 ENST00000231130.2
protocadherin beta 3
chr19_+_12949251 3.98 ENST00000251472.4
microtubule associated serine/threonine kinase 1
chr12_-_50294033 3.97 ENST00000552669.1
Fas apoptotic inhibitory molecule 2
chr2_+_210517895 3.97 ENST00000447185.1
microtubule-associated protein 2
chr1_+_159141397 3.97 ENST00000368124.4
ENST00000368125.4
ENST00000416746.1
cell adhesion molecule 3
chr1_+_66999268 3.94 ENST00000371039.1
ENST00000424320.1
SH3-domain GRB2-like (endophilin) interacting protein 1
chr10_+_18429606 3.92 ENST00000324631.7
ENST00000352115.6
ENST00000377328.1
calcium channel, voltage-dependent, beta 2 subunit
chr2_+_162272605 3.92 ENST00000389554.3
T-box, brain, 1
chr2_+_210444298 3.92 ENST00000445941.1
microtubule-associated protein 2
chr20_+_20348740 3.88 ENST00000310227.1
insulinoma-associated 1
chr8_+_105235572 3.84 ENST00000523362.1
regulating synaptic membrane exocytosis 2
chr2_-_26205550 3.82 ENST00000405914.1
kinesin family member 3C
chr17_-_56605341 3.81 ENST00000583114.1
septin 4
chr2_-_99485825 3.81 ENST00000423771.1
KIAA1211-like
chr2_+_17721920 3.80 ENST00000295156.4
visinin-like 1
chr2_+_27071045 3.80 ENST00000401478.1
dihydropyrimidinase-like 5
chr6_-_127840453 3.80 ENST00000556132.1
SOGA family member 3
chr9_-_91793675 3.80 ENST00000375835.4
ENST00000375830.1
SHC (Src homology 2 domain containing) transforming protein 3
chr14_+_101293687 3.76 ENST00000455286.1
maternally expressed 3 (non-protein coding)
chr8_+_85095013 3.73 ENST00000522613.1
RALY RNA binding protein-like
chr2_-_158182105 3.72 ENST00000409925.1
ermin, ERM-like protein
chr19_-_821931 3.72 ENST00000359894.2
ENST00000520876.3
ENST00000519502.1
hsa-mir-3187
chr3_+_178253993 3.71 ENST00000420517.2
ENST00000452583.1
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr14_-_70038032 3.70 ENST00000543986.1
coiled-coil domain containing 177
chr2_+_210443993 3.68 ENST00000392193.1
microtubule-associated protein 2
chrX_+_69642881 3.66 ENST00000453994.2
ENST00000536730.1
ENST00000538649.1
ENST00000374382.3
glycerophosphodiester phosphodiesterase domain containing 2
chr5_+_140235469 3.65 ENST00000506939.2
ENST00000307360.5
protocadherin alpha 10
chr18_-_24445729 3.65 ENST00000383168.4
aquaporin 4
chr19_-_51472823 3.65 ENST00000310157.2
kallikrein-related peptidase 6
chr14_-_60097297 3.62 ENST00000395090.1
reticulon 1
chr2_+_17721937 3.62 ENST00000451533.1
visinin-like 1
chr16_-_11375179 3.61 ENST00000312511.3
protamine 1
chr2_+_27071292 3.61 ENST00000431402.1
ENST00000434719.1
dihydropyrimidinase-like 5
chr1_+_212797789 3.60 ENST00000294829.3
family with sequence similarity 71, member A
chr3_-_116164306 3.57 ENST00000490035.2
limbic system-associated membrane protein
chr11_+_1411503 3.55 ENST00000526678.1
BR serine/threonine kinase 2
chr20_+_58203664 3.54 ENST00000541461.1
phosphatase and actin regulator 3
chr14_-_58618896 3.54 ENST00000267485.7
chromosome 14 open reading frame 37
chr16_+_30934376 3.52 ENST00000562798.1
ENST00000471231.2
F-box and leucine-rich repeat protein 19
chr22_-_39052300 3.52 ENST00000355830.6
family with sequence similarity 227, member A
chrX_-_132095419 3.51 ENST00000370836.2
ENST00000521489.1
heparan sulfate 6-O-sulfotransferase 2
chr1_-_173638976 3.50 ENST00000333279.2
ankyrin repeat domain 45
chr11_-_133715394 3.49 ENST00000299140.3
ENST00000532889.1
spermatogenesis associated 19
chr7_+_70597109 3.47 ENST00000333538.5
Williams-Beuren syndrome chromosome region 17
chr3_+_181429704 3.43 ENST00000431565.2
ENST00000325404.1
SRY (sex determining region Y)-box 2
chr16_+_58497567 3.41 ENST00000258187.5
NDRG family member 4
chr2_-_175869936 3.39 ENST00000409900.3
chimerin 1
chr17_+_36584662 3.33 ENST00000431231.2
ENST00000437668.3
Rho GTPase activating protein 23
chr18_+_21719018 3.32 ENST00000585037.1
ENST00000415309.2
ENST00000399481.2
ENST00000577705.1
ENST00000327201.6
calcium binding tyrosine-(Y)-phosphorylation regulated
chr4_-_87281196 3.30 ENST00000359221.3
mitogen-activated protein kinase 10
chr17_-_9940058 3.30 ENST00000585266.1
growth arrest-specific 7
chrX_+_86772707 3.24 ENST00000373119.4
kelch-like family member 4
chr17_+_68101117 3.23 ENST00000587698.1
ENST00000587892.1
potassium inwardly-rectifying channel, subfamily J, member 16
chr10_+_121578211 3.23 ENST00000369080.3
inositol polyphosphate-5-phosphatase F
chrX_+_92929192 3.23 ENST00000332647.4
family with sequence similarity 133, member A
chr8_-_20161466 3.22 ENST00000381569.1
leucine zipper, putative tumor suppressor 1
chr11_+_7273181 3.20 ENST00000318881.6
synaptotagmin IX
chrX_+_100333709 3.20 ENST00000372930.4
transmembrane protein 35
chr2_+_17721230 3.20 ENST00000457525.1
visinin-like 1
chr6_+_72596604 3.18 ENST00000348717.5
ENST00000517960.1
ENST00000518273.1
ENST00000522291.1
ENST00000521978.1
ENST00000520567.1
ENST00000264839.7
regulating synaptic membrane exocytosis 1
chrX_-_138287168 3.18 ENST00000436198.1
fibroblast growth factor 13
chr5_-_176900610 3.14 ENST00000477391.2
ENST00000393565.1
ENST00000309007.5
drebrin 1
chr2_+_155555201 3.14 ENST00000544049.1
potassium inwardly-rectifying channel, subfamily J, member 3
chr10_-_128359008 3.11 ENST00000488181.1
chromosome 10 open reading frame 90
chrX_-_43832711 3.10 ENST00000378062.5
Norrie disease (pseudoglioma)
chr18_-_24445664 3.09 ENST00000578776.1
aquaporin 4
chr14_-_60097524 3.08 ENST00000342503.4
reticulon 1
chr16_+_6069586 3.07 ENST00000547372.1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr1_-_177133818 3.07 ENST00000424564.2
ENST00000361833.2
astrotactin 1
chr2_-_26205340 3.07 ENST00000264712.3
kinesin family member 3C
chr7_-_22233442 3.06 ENST00000401957.2
Rap guanine nucleotide exchange factor (GEF) 5
chr13_+_30002741 3.06 ENST00000380808.2
microtubule associated tumor suppressor candidate 2
chr4_-_87281224 3.04 ENST00000395169.3
ENST00000395161.2
mitogen-activated protein kinase 10
chr5_+_140474181 3.03 ENST00000194155.4
protocadherin beta 2
chr15_-_80695917 3.03 ENST00000559008.1
Uncharacterized protein
chr10_-_61122220 3.03 ENST00000422313.2
ENST00000435852.2
ENST00000442566.3
ENST00000373868.2
ENST00000277705.6
ENST00000373867.3
ENST00000419214.2
family with sequence similarity 13, member C
chrX_+_86772787 3.02 ENST00000373114.4
kelch-like family member 4
chr17_-_9939935 3.01 ENST00000580043.1
growth arrest-specific 7
chr1_-_75100539 3.01 ENST00000420661.2
chromosome 1 open reading frame 173
chr18_+_55018044 3.01 ENST00000324000.3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr19_-_6501778 2.96 ENST00000596291.1
tubulin, beta 4A class IVa
chr5_-_176037105 2.95 ENST00000303991.4
G protein regulated inducer of neurite outgrowth 1
chr1_+_92632542 2.95 ENST00000409154.4
ENST00000370378.4
KIAA1107
chrX_+_9880412 2.95 ENST00000418909.2
shroom family member 2
chr2_+_69240302 2.94 ENST00000303714.4
anthrax toxin receptor 1
chr19_-_42498369 2.93 ENST00000302102.5
ENST00000545399.1
ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr3_-_116163830 2.93 ENST00000333617.4
limbic system-associated membrane protein
chr16_+_58497587 2.92 ENST00000569404.1
ENST00000569539.1
ENST00000564126.1
ENST00000565304.1
ENST00000567667.1
NDRG family member 4
chr19_-_42498231 2.90 ENST00000602133.1
ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr2_+_69240511 2.89 ENST00000409349.3
anthrax toxin receptor 1
chr8_+_30496078 2.88 ENST00000517349.1
small integral membrane protein 18
chr6_+_69942915 2.87 ENST00000604969.1
ENST00000603207.1
brain-specific angiogenesis inhibitor 3
chr8_+_79578282 2.87 ENST00000263849.4
zinc finger, C2HC-type containing 1A
chrX_-_80457385 2.86 ENST00000451455.1
ENST00000436386.1
ENST00000358130.2
high mobility group nucleosome binding domain 5
chrX_-_24690771 2.86 ENST00000379145.1
phosphate cytidylyltransferase 1, choline, beta
chr17_+_40119801 2.84 ENST00000585452.1
2',3'-cyclic nucleotide 3' phosphodiesterase
chr20_-_30458019 2.83 ENST00000486996.1
ENST00000398084.2
dual specificity phosphatase 15
chr6_-_134639235 2.82 ENST00000533224.1
serum/glucocorticoid regulated kinase 1
chr16_+_6069072 2.81 ENST00000547605.1
ENST00000550418.1
ENST00000553186.1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr22_+_19701985 2.80 ENST00000455784.2
ENST00000406395.1
septin 5
chr6_+_97372596 2.79 ENST00000369261.4
kelch-like family member 32
chr1_-_31712401 2.79 ENST00000373736.2
Na+/K+ transporting ATPase interacting 1
chr1_+_50569575 2.78 ENST00000371827.1
ELAV like neuron-specific RNA binding protein 4
chr10_-_104179682 2.77 ENST00000406432.1
pleckstrin and Sec7 domain containing
chr9_+_95947198 2.77 ENST00000448039.1
ENST00000297954.4
ENST00000395477.2
ENST00000395475.2
ENST00000349097.3
ENST00000427277.2
ENST00000356055.3
ENST00000432730.1
WNK lysine deficient protein kinase 2
chr7_-_112727774 2.77 ENST00000297146.3
ENST00000501255.2
G protein-coupled receptor 85
chr3_-_149688971 2.77 ENST00000498307.1
ENST00000489155.1
profilin 2
chr7_-_107968921 2.75 ENST00000442580.1
neuronal cell adhesion molecule
chr7_+_94537542 2.74 ENST00000433881.1
protein phosphatase 1, regulatory subunit 9A
chr2_-_152955537 2.73 ENST00000201943.5
ENST00000539935.1
calcium channel, voltage-dependent, beta 4 subunit
chr7_-_19813192 2.73 ENST00000422233.1
ENST00000433641.1
transmembrane protein 196
chr22_+_19702069 2.73 ENST00000412544.1
septin 5
chr13_+_113656092 2.72 ENST00000397024.1
MCF.2 cell line derived transforming sequence-like
chr12_-_81763184 2.71 ENST00000548670.1
ENST00000541570.2
ENST00000553058.1
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr13_-_25754077 2.70 ENST00000413501.1
AMER2 antisense RNA 1 (head to head)
chr11_+_66045634 2.70 ENST00000528852.1
ENST00000311445.6
cornichon family AMPA receptor auxiliary protein 2
chr10_+_73724123 2.70 ENST00000373115.4
carbohydrate (chondroitin 6) sulfotransferase 3
chr4_+_150999418 2.70 ENST00000296550.7
doublecortin-like kinase 2
chr1_+_200708671 2.69 ENST00000358823.2
calmodulin regulated spectrin-associated protein family, member 2
chr16_-_75529273 2.68 ENST00000390664.2
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6
chr15_+_84116106 2.68 ENST00000535412.1
ENST00000324537.5
SH3-domain GRB2-like 3

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX3_SOX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.7 GO:0051466 positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
2.7 18.8 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
2.4 7.2 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
1.8 5.5 GO:0032242 regulation of nucleoside transport(GO:0032242)
1.8 5.5 GO:1904530 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
1.8 5.4 GO:0008057 eye pigment granule organization(GO:0008057)
1.7 10.4 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
1.5 4.4 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
1.4 8.6 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
1.4 5.7 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
1.4 9.7 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
1.3 9.0 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
1.2 3.5 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
1.2 19.9 GO:0030050 vesicle transport along actin filament(GO:0030050)
1.1 12.4 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
1.1 9.8 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
1.1 12.6 GO:0006657 CDP-choline pathway(GO:0006657)
1.0 21.0 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.9 4.7 GO:0021586 pons maturation(GO:0021586)
0.9 3.6 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.9 7.7 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.8 3.2 GO:0003358 noradrenergic neuron development(GO:0003358)
0.8 3.8 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.8 3.0 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.7 7.9 GO:1902988 neurofibrillary tangle assembly(GO:1902988)
0.7 2.7 GO:0019056 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.7 2.0 GO:0007412 axon target recognition(GO:0007412)
0.7 2.6 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
0.6 3.9 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.6 1.9 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.6 3.8 GO:0021764 amygdala development(GO:0021764)
0.6 1.9 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.6 13.9 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.6 3.0 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.6 8.4 GO:0016198 axon choice point recognition(GO:0016198)
0.6 2.4 GO:0070662 mast cell proliferation(GO:0070662)
0.6 3.6 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.6 2.9 GO:0036371 protein localization to T-tubule(GO:0036371)
0.6 3.5 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.6 2.3 GO:0050976 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976)
0.6 5.8 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.6 1.7 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.6 3.3 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.6 4.4 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.5 7.4 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.5 3.1 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.5 1.6 GO:0005989 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.5 1.5 GO:0060304 regulation of phosphatidylinositol dephosphorylation(GO:0060304)
0.5 2.5 GO:0007538 primary sex determination(GO:0007538)
0.5 2.0 GO:0035262 gonad morphogenesis(GO:0035262)
0.5 14.1 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.5 2.4 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.5 3.2 GO:1903281 positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.5 1.8 GO:0097106 postsynaptic density organization(GO:0097106)
0.5 6.8 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.5 6.3 GO:0007258 JUN phosphorylation(GO:0007258)
0.5 2.3 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258)
0.5 1.4 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.4 1.8 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.4 6.1 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.4 7.7 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.4 7.7 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.4 1.3 GO:0035602 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604)
0.4 0.4 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.4 15.7 GO:0001573 ganglioside metabolic process(GO:0001573)
0.4 1.3 GO:1905133 metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.4 1.7 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.4 1.3 GO:1904179 positive regulation of adipose tissue development(GO:1904179)
0.4 1.3 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.4 2.1 GO:0031291 Ran protein signal transduction(GO:0031291)
0.4 1.2 GO:0061075 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.4 2.0 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.4 3.2 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.4 2.0 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.4 9.0 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.4 4.3 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.4 0.8 GO:0014016 neuroblast differentiation(GO:0014016)
0.4 1.5 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.4 0.7 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.4 1.5 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.4 0.7 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.4 0.7 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952)
0.4 2.5 GO:1901318 negative regulation of sperm motility(GO:1901318)
0.4 3.9 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.3 2.1 GO:0071503 response to heparin(GO:0071503)
0.3 7.8 GO:0021681 cerebellar granular layer development(GO:0021681)
0.3 2.4 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.3 1.0 GO:1900737 regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.3 4.3 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.3 3.9 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.3 5.3 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.3 4.9 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.3 1.0 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.3 10.1 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.3 1.9 GO:0021633 optic nerve structural organization(GO:0021633)
0.3 1.6 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.3 2.2 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.3 7.3 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.3 1.6 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.3 0.6 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.3 10.5 GO:0048240 sperm capacitation(GO:0048240)
0.3 4.1 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.3 0.3 GO:0070100 negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.3 2.0 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.3 6.5 GO:0035641 locomotory exploration behavior(GO:0035641)
0.3 2.5 GO:0021860 pyramidal neuron development(GO:0021860)
0.3 16.6 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.3 0.8 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.3 0.8 GO:0060129 regulation of calcium-independent cell-cell adhesion(GO:0051040) thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.3 1.6 GO:1901631 postsynaptic membrane assembly(GO:0097104) positive regulation of presynaptic membrane organization(GO:1901631) positive regulation of synaptic vesicle clustering(GO:2000809)
0.3 1.6 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.3 4.3 GO:0042749 regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.3 2.2 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.3 3.8 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.3 4.0 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.3 1.6 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.3 8.2 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.3 2.4 GO:0021564 vagus nerve development(GO:0021564)
0.3 5.0 GO:0046069 cGMP catabolic process(GO:0046069)
0.3 1.3 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.3 0.5 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.2 0.7 GO:0060166 olfactory pit development(GO:0060166)
0.2 0.7 GO:0031133 regulation of axon diameter(GO:0031133)
0.2 0.7 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.2 4.3 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.2 2.2 GO:1902669 positive regulation of axon guidance(GO:1902669)
0.2 0.2 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.2 4.5 GO:0007021 tubulin complex assembly(GO:0007021)
0.2 1.6 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.2 1.2 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.2 3.9 GO:0006776 vitamin A metabolic process(GO:0006776)
0.2 2.7 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.2 0.7 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.2 1.4 GO:0035063 nuclear speck organization(GO:0035063)
0.2 6.1 GO:0005513 detection of calcium ion(GO:0005513)
0.2 1.8 GO:0019236 response to pheromone(GO:0019236)
0.2 0.7 GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.2 5.4 GO:0097120 receptor localization to synapse(GO:0097120)
0.2 3.6 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.2 0.7 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.2 2.2 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.2 1.3 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.2 3.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.2 0.6 GO:2000584 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.2 3.4 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.2 1.0 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.2 3.1 GO:0060134 prepulse inhibition(GO:0060134)
0.2 1.3 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.2 1.4 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.2 6.7 GO:0006833 water transport(GO:0006833)
0.2 0.6 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.2 3.4 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.2 7.3 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.2 0.6 GO:0035425 autocrine signaling(GO:0035425)
0.2 3.4 GO:0021984 adenohypophysis development(GO:0021984)
0.2 1.0 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.2 1.2 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)
0.2 2.2 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.2 2.2 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.2 1.8 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.2 0.6 GO:1903461 Okazaki fragment processing involved in mitotic DNA replication(GO:1903461)
0.2 3.9 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.2 0.6 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.2 0.6 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.2 8.9 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.2 1.3 GO:0051684 maintenance of Golgi location(GO:0051684)
0.2 0.6 GO:0046022 positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.2 2.5 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.2 1.5 GO:0003322 pancreatic A cell development(GO:0003322)
0.2 1.1 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.2 3.3 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.2 1.7 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.2 3.3 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.2 2.9 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.2 3.9 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.2 1.3 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.2 4.3 GO:0015865 purine nucleotide transport(GO:0015865)
0.2 3.0 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.2 0.9 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.2 0.5 GO:0032229 negative regulation of glutamate secretion(GO:0014050) negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.2 0.9 GO:0048104 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.2 1.9 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.2 3.6 GO:0090527 actin filament reorganization(GO:0090527)
0.2 1.7 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593) negative regulation of lamellipodium organization(GO:1902744)
0.2 6.1 GO:0014047 glutamate secretion(GO:0014047)
0.2 2.2 GO:2000662 interleukin-5 secretion(GO:0072603) regulation of interleukin-5 secretion(GO:2000662)
0.2 2.9 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.2 1.3 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.2 1.8 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.2 1.0 GO:0071286 cellular response to magnesium ion(GO:0071286)
0.2 1.3 GO:2000508 regulation of dendritic cell chemotaxis(GO:2000508)
0.2 0.5 GO:0035750 protein localization to myelin sheath abaxonal region(GO:0035750)
0.2 0.6 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.2 4.0 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.2 2.1 GO:1903817 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.2 18.8 GO:0021954 central nervous system neuron development(GO:0021954)
0.2 3.7 GO:0016048 detection of temperature stimulus(GO:0016048)
0.2 0.8 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.2 0.8 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.2 2.5 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.2 2.8 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.2 0.6 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.2 0.5 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.2 2.3 GO:0071420 cellular response to histamine(GO:0071420)
0.2 0.8 GO:0060113 inner ear receptor cell differentiation(GO:0060113)
0.1 32.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 1.2 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.1 2.8 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.1 1.0 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.1 0.9 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 2.1 GO:0045176 apical protein localization(GO:0045176)
0.1 0.7 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.6 GO:0050482 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.1 0.4 GO:0042489 negative regulation of odontogenesis of dentin-containing tooth(GO:0042489)
0.1 5.3 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.1 0.9 GO:0061436 establishment of skin barrier(GO:0061436)
0.1 1.0 GO:0035494 SNARE complex disassembly(GO:0035494)
0.1 3.6 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 0.9 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 0.4 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.1 0.8 GO:0042816 vitamin B6 metabolic process(GO:0042816)
0.1 1.7 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.1 0.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 1.5 GO:2000463 positive regulation of excitatory postsynaptic potential(GO:2000463)
0.1 0.4 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.1 6.0 GO:0010107 potassium ion import(GO:0010107)
0.1 1.6 GO:0060453 regulation of gastric acid secretion(GO:0060453)
0.1 0.9 GO:0032808 lacrimal gland development(GO:0032808)
0.1 1.3 GO:0010265 SCF complex assembly(GO:0010265)
0.1 9.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 1.2 GO:0032596 protein transport into membrane raft(GO:0032596)
0.1 1.0 GO:0033007 negative regulation of mast cell activation involved in immune response(GO:0033007) negative regulation of mast cell degranulation(GO:0043305)
0.1 1.3 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.1 9.1 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.1 1.4 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.1 0.3 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.1 1.6 GO:0009249 protein lipoylation(GO:0009249)
0.1 1.3 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 1.4 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1 2.0 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.1 0.6 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.1 1.8 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 0.7 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.1 0.9 GO:0023041 neuronal signal transduction(GO:0023041)
0.1 0.8 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.1 3.8 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.1 1.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 2.9 GO:0042359 vitamin D metabolic process(GO:0042359)
0.1 1.9 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 1.5 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.1 2.3 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 1.1 GO:0021554 optic nerve development(GO:0021554)
0.1 2.0 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1 1.2 GO:0048752 semicircular canal morphogenesis(GO:0048752) semicircular canal development(GO:0060872)
0.1 3.4 GO:0048713 regulation of oligodendrocyte differentiation(GO:0048713)
0.1 4.3 GO:0007398 ectoderm development(GO:0007398)
0.1 11.3 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 3.4 GO:0010644 cell communication by electrical coupling(GO:0010644)
0.1 0.8 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 1.5 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.1 0.8 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.1 0.5 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.1 0.6 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.1 2.1 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 1.2 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.1 0.6 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.1 1.9 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.1 1.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 0.7 GO:0043524 negative regulation of neuron apoptotic process(GO:0043524)
0.1 2.5 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 2.2 GO:1904152 regulation of retrograde protein transport, ER to cytosol(GO:1904152)
0.1 5.1 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1 0.5 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.1 4.5 GO:0030261 chromosome condensation(GO:0030261)
0.1 0.7 GO:0046477 glycosylceramide catabolic process(GO:0046477) glycosphingolipid catabolic process(GO:0046479)
0.1 0.3 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
0.1 7.4 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1 2.6 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.1 0.5 GO:0035754 B cell chemotaxis(GO:0035754)
0.1 0.3 GO:0045988 negative regulation of striated muscle contraction(GO:0045988) negative regulation of cardiac muscle contraction(GO:0055118)
0.1 0.6 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 1.5 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.1 0.3 GO:0007343 egg activation(GO:0007343)
0.1 1.4 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.1 0.7 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.1 0.4 GO:1901166 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) neural crest cell migration involved in autonomic nervous system development(GO:1901166) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.1 2.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.4 GO:0001781 neutrophil apoptotic process(GO:0001781) regulation of neutrophil apoptotic process(GO:0033029)
0.1 3.8 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 0.6 GO:0015791 polyol transport(GO:0015791)
0.1 0.8 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 1.9 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.1 0.5 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 1.4 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.1 0.5 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.1 2.6 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 0.4 GO:0008343 adult feeding behavior(GO:0008343)
0.1 1.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.5 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 1.3 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.1 8.0 GO:0061337 cardiac conduction(GO:0061337)
0.1 0.7 GO:0048263 determination of dorsal identity(GO:0048263)
0.1 1.1 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1 1.5 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 1.5 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1 0.9 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.4 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112)
0.1 0.7 GO:0010664 negative regulation of striated muscle cell apoptotic process(GO:0010664) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.1 0.6 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 1.6 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.1 0.9 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 4.3 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.1 1.5 GO:0019228 neuronal action potential(GO:0019228)
0.1 1.0 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.1 1.1 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 2.3 GO:0007340 acrosome reaction(GO:0007340)
0.1 2.7 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 0.5 GO:0061511 centriole elongation(GO:0061511)
0.1 0.5 GO:0032092 positive regulation of protein binding(GO:0032092)
0.1 0.6 GO:0072520 seminiferous tubule development(GO:0072520)
0.1 0.6 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.1 1.2 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.1 0.2 GO:0006601 creatine biosynthetic process(GO:0006601)
0.1 0.6 GO:0015705 iodide transport(GO:0015705)
0.1 0.2 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.1 0.7 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.1 0.4 GO:0035640 exploration behavior(GO:0035640)
0.1 0.5 GO:0036109 alpha-linolenic acid metabolic process(GO:0036109) linoleic acid metabolic process(GO:0043651)
0.1 1.9 GO:0006825 copper ion transport(GO:0006825)
0.1 0.9 GO:0007129 synapsis(GO:0007129)
0.1 0.4 GO:0032468 Golgi calcium ion homeostasis(GO:0032468) Golgi calcium ion transport(GO:0032472)
0.1 0.7 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1 2.4 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.1 0.9 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.1 0.7 GO:0035092 sperm chromatin condensation(GO:0035092)
0.1 0.1 GO:0071211 protein targeting to lysosome involved in chaperone-mediated autophagy(GO:0061740) protein targeting to vacuole involved in autophagy(GO:0071211)
0.1 0.7 GO:0006020 inositol metabolic process(GO:0006020)
0.1 1.1 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 2.2 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 5.6 GO:0030534 adult behavior(GO:0030534)
0.1 1.5 GO:0009437 carnitine metabolic process(GO:0009437)
0.1 0.1 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.1 3.9 GO:0015701 bicarbonate transport(GO:0015701)
0.1 2.7 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.1 1.0 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 0.8 GO:0001508 action potential(GO:0001508)
0.1 0.6 GO:0000733 DNA strand renaturation(GO:0000733)
0.1 0.5 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.1 0.3 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.1 1.7 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 0.3 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 1.1 GO:0014037 Schwann cell differentiation(GO:0014037)
0.0 0.4 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.0 0.5 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.0 2.1 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.6 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.3 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 0.2 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.0 1.9 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.7 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.6 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.5 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.8 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.0 0.8 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.4 GO:0045026 plasma membrane fusion(GO:0045026)
0.0 0.3 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.0 0.2 GO:0008218 bioluminescence(GO:0008218)
0.0 1.5 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.9 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.5 GO:0060290 transdifferentiation(GO:0060290)
0.0 0.2 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.0 GO:0006408 snRNA export from nucleus(GO:0006408)
0.0 1.2 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.2 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.7 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.4 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.3 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.4 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.5 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0 0.3 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 1.4 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.7 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.9 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.0 0.4 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.5 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.0 1.7 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.4 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 1.0 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.2 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 0.3 GO:0042659 regulation of cell fate specification(GO:0042659)
0.0 0.5 GO:2000194 regulation of female gonad development(GO:2000194)
0.0 1.0 GO:0015695 organic cation transport(GO:0015695)
0.0 0.4 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.4 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.0 0.4 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.7 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.4 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.0 2.2 GO:0031440 regulation of mRNA 3'-end processing(GO:0031440)
0.0 1.6 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.1 GO:0060838 radial pattern formation(GO:0009956) lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.0 0.2 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.0 2.6 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.3 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.5 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.4 GO:0009750 response to fructose(GO:0009750)
0.0 0.7 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.4 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 1.1 GO:0045124 regulation of bone resorption(GO:0045124)
0.0 0.3 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.4 GO:1900016 negative regulation of cytokine production involved in inflammatory response(GO:1900016)
0.0 0.3 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.1 GO:0021503 neural fold bending(GO:0021503)
0.0 0.5 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 5.6 GO:0007411 axon guidance(GO:0007411)
0.0 0.7 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 1.1 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.8 GO:0010737 protein kinase A signaling(GO:0010737)
0.0 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.0 GO:0070525 tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.0 0.2 GO:0002793 positive regulation of peptide secretion(GO:0002793) positive regulation of peptide hormone secretion(GO:0090277)
0.0 0.4 GO:0014003 oligodendrocyte development(GO:0014003)
0.0 2.9 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.4 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 4.3 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.2 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.1 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.4 GO:0031529 ruffle organization(GO:0031529)
0.0 1.9 GO:0001764 neuron migration(GO:0001764)
0.0 0.5 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 3.5 GO:0007409 axonogenesis(GO:0007409)
0.0 8.2 GO:0010506 regulation of autophagy(GO:0010506)
0.0 0.2 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.2 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 0.7 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.0 2.2 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.3 GO:0045932 negative regulation of muscle contraction(GO:0045932)
0.0 0.2 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.0 0.1 GO:0001541 ovarian follicle development(GO:0001541)
0.0 0.7 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 0.4 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.0 0.4 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.0 4.8 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 1.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.8 GO:0046785 microtubule polymerization(GO:0046785)
0.0 0.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.6 GO:0014075 response to amine(GO:0014075)
0.0 0.3 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 2.9 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.2 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.0 0.1 GO:0046707 IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709)
0.0 0.9 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 1.6 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.0 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.8 GO:0007041 lysosomal transport(GO:0007041)
0.0 1.6 GO:0008652 cellular amino acid biosynthetic process(GO:0008652)
0.0 0.1 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.3 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 0.5 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.2 GO:0003014 renal system process(GO:0003014)
0.0 0.1 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.6 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.2 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.0 0.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.5 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 0.1 GO:0070570 regulation of neuron projection regeneration(GO:0070570)
0.0 0.2 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.3 GO:0061157 mRNA destabilization(GO:0061157)
0.0 0.2 GO:0045851 pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.0 1.3 GO:0007286 spermatid development(GO:0007286)
0.0 0.4 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.1 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.2 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.2 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.0 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.6 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 0.4 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 8.9 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
2.4 33.8 GO:0033269 internode region of axon(GO:0033269)
1.8 19.6 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
1.1 9.5 GO:0044326 dendritic spine neck(GO:0044326)
0.9 5.3 GO:1990769 proximal neuron projection(GO:1990769)
0.7 9.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.7 2.0 GO:0098855 HCN channel complex(GO:0098855)
0.6 4.3 GO:0045298 tubulin complex(GO:0045298)
0.6 9.7 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.6 10.7 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.5 2.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.5 1.6 GO:0044305 calyx of Held(GO:0044305)
0.5 2.4 GO:0002079 inner acrosomal membrane(GO:0002079)
0.4 3.0 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.4 3.6 GO:0071547 piP-body(GO:0071547)
0.4 1.5 GO:0060187 cell pole(GO:0060187)
0.4 10.2 GO:0005922 connexon complex(GO:0005922)
0.4 24.4 GO:0048786 presynaptic active zone(GO:0048786)
0.4 1.8 GO:0005606 laminin-1 complex(GO:0005606)
0.3 1.0 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.3 2.9 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.3 4.6 GO:0097418 neurofibrillary tangle(GO:0097418)
0.3 5.5 GO:0097512 cardiac myofibril(GO:0097512)
0.3 9.0 GO:0043194 axon initial segment(GO:0043194)
0.3 4.8 GO:0001520 outer dense fiber(GO:0001520)
0.3 1.8 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.3 7.7 GO:0031045 dense core granule(GO:0031045)
0.3 13.0 GO:0031258 lamellipodium membrane(GO:0031258)
0.3 8.4 GO:0071565 nBAF complex(GO:0071565)
0.3 1.6 GO:0005594 collagen type IX trimer(GO:0005594)
0.3 1.0 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.3 2.1 GO:1990635 proximal dendrite(GO:1990635)
0.3 6.2 GO:0032433 filopodium tip(GO:0032433)
0.3 2.6 GO:0098839 postsynaptic density membrane(GO:0098839)
0.3 2.0 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.3 12.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 4.5 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.2 4.5 GO:0097227 sperm annulus(GO:0097227)
0.2 0.9 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.2 8.9 GO:0044295 axonal growth cone(GO:0044295)
0.2 35.7 GO:0034705 potassium channel complex(GO:0034705)
0.2 2.8 GO:0097524 sperm plasma membrane(GO:0097524)
0.2 19.5 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.2 6.6 GO:0005614 interstitial matrix(GO:0005614)
0.2 19.5 GO:0043195 terminal bouton(GO:0043195)
0.2 2.7 GO:0005921 gap junction(GO:0005921)
0.2 1.8 GO:0030893 meiotic cohesin complex(GO:0030893)
0.2 1.7 GO:0002116 semaphorin receptor complex(GO:0002116)
0.2 0.9 GO:0044393 microspike(GO:0044393)
0.2 0.5 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.2 8.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.2 3.9 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.2 41.7 GO:0030426 growth cone(GO:0030426)
0.2 1.6 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.2 1.4 GO:0098845 postsynaptic endosome(GO:0098845)
0.2 1.2 GO:0097386 glial cell projection(GO:0097386)
0.2 4.0 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.2 2.6 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.2 20.8 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 2.5 GO:0061700 GATOR2 complex(GO:0061700)
0.1 0.4 GO:0035189 Rb-E2F complex(GO:0035189)
0.1 1.9 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 1.6 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 1.0 GO:0043219 lateral loop(GO:0043219)
0.1 0.4 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.1 1.1 GO:0045180 basal cortex(GO:0045180)
0.1 3.0 GO:0005686 U2 snRNP(GO:0005686)
0.1 0.8 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.9 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 0.8 GO:0097427 microtubule bundle(GO:0097427)
0.1 0.8 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 38.6 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 2.8 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 0.3 GO:0035101 FACT complex(GO:0035101)
0.1 0.3 GO:0005960 glycine cleavage complex(GO:0005960)
0.1 0.4 GO:1902912 pyruvate kinase complex(GO:1902912)
0.1 1.5 GO:0097225 sperm midpiece(GO:0097225)
0.1 2.8 GO:1990752 microtubule end(GO:1990752)
0.1 2.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 2.2 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 8.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 6.5 GO:0097542 ciliary tip(GO:0097542)
0.1 0.6 GO:0008537 proteasome activator complex(GO:0008537)
0.1 6.3 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 0.3 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.1 0.3 GO:0005595 collagen type XII trimer(GO:0005595)
0.1 0.3 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1 1.5 GO:0045179 apical cortex(GO:0045179)
0.1 0.9 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 2.0 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 1.5 GO:0000145 exocyst(GO:0000145)
0.1 4.4 GO:0034704 calcium channel complex(GO:0034704)
0.1 0.7 GO:0034451 centriolar satellite(GO:0034451)
0.1 7.5 GO:0043204 perikaryon(GO:0043204)
0.1 1.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.4 GO:0030057 desmosome(GO:0030057)
0.1 4.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 8.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 2.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 1.3 GO:0043198 dendritic shaft(GO:0043198)
0.1 1.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.5 GO:0031262 Ndc80 complex(GO:0031262)
0.1 3.9 GO:0044306 neuron projection terminus(GO:0044306)
0.1 0.8 GO:0034709 methylosome(GO:0034709)
0.1 1.1 GO:0030673 axolemma(GO:0030673)
0.1 18.5 GO:0030424 axon(GO:0030424)
0.1 1.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 18.3 GO:0043025 neuronal cell body(GO:0043025)
0.1 28.2 GO:0043005 neuron projection(GO:0043005)
0.1 5.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 0.5 GO:0005869 dynactin complex(GO:0005869)
0.1 1.9 GO:0042629 mast cell granule(GO:0042629)
0.1 2.6 GO:0005923 bicellular tight junction(GO:0005923)
0.1 11.7 GO:0043209 myelin sheath(GO:0043209)
0.1 0.8 GO:0097433 dense body(GO:0097433)
0.1 2.3 GO:0031594 neuromuscular junction(GO:0031594)
0.1 0.1 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.1 1.2 GO:0000812 Swr1 complex(GO:0000812)
0.1 0.4 GO:0035869 ciliary transition zone(GO:0035869)
0.1 10.7 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.1 5.8 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.1 0.6 GO:0005875 microtubule associated complex(GO:0005875)
0.1 10.5 GO:0031225 anchored component of membrane(GO:0031225)
0.1 3.6 GO:0000786 nucleosome(GO:0000786)
0.0 0.6 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.5 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 1.6 GO:0009925 basal plasma membrane(GO:0009925)
0.0 13.4 GO:0031253 cell projection membrane(GO:0031253)
0.0 1.8 GO:0031201 SNARE complex(GO:0031201)
0.0 1.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 2.4 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.6 GO:0031984 organelle subcompartment(GO:0031984)
0.0 1.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.2 GO:0031213 RSF complex(GO:0031213)
0.0 1.0 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 3.2 GO:0005902 microvillus(GO:0005902)
0.0 1.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.7 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.8 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 1.5 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.3 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 1.3 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.3 GO:0016011 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0 0.4 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.7 GO:0044297 cell body(GO:0044297)
0.0 5.5 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.2 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 1.3 GO:0060076 excitatory synapse(GO:0060076)
0.0 1.1 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 1.8 GO:0045171 intercellular bridge(GO:0045171)
0.0 4.3 GO:0030496 midbody(GO:0030496)
0.0 2.1 GO:0001533 cornified envelope(GO:0001533)
0.0 5.2 GO:0030027 lamellipodium(GO:0030027)
0.0 0.3 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.1 GO:0036338 viral envelope(GO:0019031) viral membrane(GO:0036338)
0.0 0.5 GO:0010369 chromocenter(GO:0010369)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 3.6 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 0.4 GO:0005771 multivesicular body(GO:0005771)
0.0 1.6 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 1.4 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124)
0.0 2.1 GO:0005929 cilium(GO:0005929)
0.0 0.5 GO:0000776 kinetochore(GO:0000776)
0.0 0.1 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.7 GO:0005871 kinesin complex(GO:0005871)
0.0 3.4 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0036038 MKS complex(GO:0036038)
0.0 0.3 GO:0032420 stereocilium(GO:0032420)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.3 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.9 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.3 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 49.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
2.5 12.6 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
1.5 8.9 GO:1990430 extracellular matrix protein binding(GO:1990430)
1.1 4.6 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
1.1 5.5 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
1.1 15.8 GO:0035374 chondroitin sulfate binding(GO:0035374)
1.0 3.1 GO:0072591 citrate-L-glutamate ligase activity(GO:0072591)
0.9 5.7 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.9 8.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.9 3.5 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.8 3.3 GO:0099609 microtubule lateral binding(GO:0099609)
0.8 9.7 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.8 2.3 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.7 2.2 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.7 2.8 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.7 2.1 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.7 5.4 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.7 21.4 GO:0002162 dystroglycan binding(GO:0002162)
0.7 3.3 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.7 6.5 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.6 3.0 GO:0070052 collagen V binding(GO:0070052)
0.6 1.8 GO:0016503 pheromone receptor activity(GO:0016503)
0.6 1.2 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.6 2.3 GO:0008431 vitamin E binding(GO:0008431)
0.5 1.6 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.5 1.6 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.5 2.1 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.5 6.3 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.5 2.0 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.5 4.9 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.5 2.4 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.5 5.1 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.5 2.3 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.4 3.1 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.4 3.0 GO:0031849 olfactory receptor binding(GO:0031849)
0.4 2.2 GO:0003947 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity(GO:0003947)
0.4 4.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.4 7.7 GO:0015250 water channel activity(GO:0015250)
0.4 1.3 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.4 9.8 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.4 4.5 GO:0005243 gap junction channel activity(GO:0005243)
0.4 2.0 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.4 2.8 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.4 2.0 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.4 17.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.4 3.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.4 1.6 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.4 2.6 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.4 1.8 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.4 3.2 GO:0052832 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.4 6.7 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.3 2.8 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.3 1.4 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.3 1.3 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.3 3.6 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.3 2.2 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.3 1.6 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.3 5.9 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.3 3.6 GO:0016594 glycine binding(GO:0016594)
0.3 1.1 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.3 5.7 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.3 2.3 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.3 5.4 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.3 10.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.3 2.6 GO:0030332 cyclin binding(GO:0030332)
0.3 3.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.3 1.6 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.3 2.4 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.3 2.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.3 2.1 GO:0035473 lipase binding(GO:0035473)
0.2 1.0 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.2 1.7 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.2 2.7 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.2 3.4 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.2 0.7 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.2 1.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 2.4 GO:0005539 glycosaminoglycan binding(GO:0005539)
0.2 1.6 GO:0005502 11-cis retinal binding(GO:0005502)
0.2 2.7 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.2 4.4 GO:0008179 adenylate cyclase binding(GO:0008179)
0.2 5.8 GO:0031005 filamin binding(GO:0031005)
0.2 1.8 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.2 1.5 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.2 3.1 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.2 3.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.2 0.9 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.2 3.8 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.2 3.8 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.2 5.1 GO:0050321 tau-protein kinase activity(GO:0050321)
0.2 26.0 GO:0015459 potassium channel regulator activity(GO:0015459)
0.2 1.9 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.2 3.7 GO:0003796 lysozyme activity(GO:0003796)
0.2 2.7 GO:0017048 Rho GTPase binding(GO:0017048)
0.2 1.9 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.2 0.8 GO:0019211 phosphatase activator activity(GO:0019211)
0.2 12.9 GO:0030507 spectrin binding(GO:0030507)
0.2 8.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 21.4 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.2 1.8 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.2 2.4 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 0.8 GO:0015616 DNA translocase activity(GO:0015616)
0.2 1.5 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.2 0.9 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.2 5.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 0.7 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.2 1.8 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.2 0.5 GO:0002113 interleukin-33 binding(GO:0002113)
0.2 1.4 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.2 1.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.2 1.4 GO:0032051 clathrin light chain binding(GO:0032051)
0.2 2.6 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.2 1.2 GO:0016403 dimethylargininase activity(GO:0016403)
0.2 0.5 GO:0004967 glucagon receptor activity(GO:0004967)
0.2 9.0 GO:0046875 ephrin receptor binding(GO:0046875)
0.2 1.9 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.2 1.0 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.2 1.3 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.2 1.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 8.4 GO:0051393 alpha-actinin binding(GO:0051393)
0.2 0.7 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.2 7.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 0.5 GO:0045485 omega-6 fatty acid desaturase activity(GO:0045485)
0.2 1.6 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.2 1.3 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.2 9.0 GO:0004364 glutathione transferase activity(GO:0004364)
0.2 0.8 GO:0033265 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
0.2 0.6 GO:0031493 nucleosomal histone binding(GO:0031493)
0.2 1.9 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 4.3 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.2 2.3 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.2 3.5 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.3 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.1 0.7 GO:0005113 patched binding(GO:0005113)
0.1 0.6 GO:0032551 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
0.1 5.2 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 7.3 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 4.9 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.1 0.4 GO:0043849 Ras palmitoyltransferase activity(GO:0043849)
0.1 1.0 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 1.4 GO:0004111 creatine kinase activity(GO:0004111)
0.1 7.2 GO:0017091 AU-rich element binding(GO:0017091)
0.1 1.7 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 1.3 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 0.3 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.1 0.5 GO:0001601 peptide YY receptor activity(GO:0001601)
0.1 2.5 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 6.0 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 0.8 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 5.2 GO:0016805 dipeptidase activity(GO:0016805)
0.1 2.4 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 17.9 GO:0005262 calcium channel activity(GO:0005262)
0.1 0.9 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 3.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.5 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.1 1.2 GO:0051425 PTB domain binding(GO:0051425)
0.1 1.3 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.6 GO:0038025 reelin receptor activity(GO:0038025)
0.1 1.5 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 4.0 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 5.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 1.0 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1 20.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 1.3 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 0.4 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.1 1.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 2.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 1.0 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.1 0.4 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.1 3.3 GO:0005523 tropomyosin binding(GO:0005523)
0.1 12.8 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 0.5 GO:0097677 STAT family protein binding(GO:0097677)
0.1 1.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 2.7 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.1 1.5 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 1.5 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 3.4 GO:0019894 kinesin binding(GO:0019894)
0.1 0.4 GO:0031545 peptidyl-proline dioxygenase activity(GO:0031543) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 3.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 2.5 GO:0035198 miRNA binding(GO:0035198)
0.1 50.9 GO:0015631 tubulin binding(GO:0015631)
0.1 1.7 GO:1990459 transferrin receptor binding(GO:1990459)
0.1 0.7 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 2.5 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 1.2 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 0.4 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.1 1.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 0.4 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 1.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.6 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.5 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 0.5 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.1 0.8 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1 1.5 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 0.2 GO:0015068 amidinotransferase activity(GO:0015067) glycine amidinotransferase activity(GO:0015068)
0.1 1.1 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.2 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.1 0.4 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 0.7 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 0.7 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.1 0.2 GO:0030613 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
0.1 1.5 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.1 0.5 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.1 2.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 1.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 1.6 GO:0005522 profilin binding(GO:0005522)
0.1 1.0 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.1 0.9 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 1.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 2.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 1.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.6 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.1 1.4 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.1 1.8 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 1.2 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.1 1.5 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 0.4 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.5 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 2.3 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 3.4 GO:0005109 frizzled binding(GO:0005109)
0.1 0.5 GO:1904047 histone methyltransferase activity (H3-K9 specific)(GO:0046974) S-adenosyl-L-methionine binding(GO:1904047)
0.1 0.8 GO:0034056 estrogen response element binding(GO:0034056)
0.1 3.2 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 0.3 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.9 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 0.3 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.1 1.0 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 2.0 GO:0042056 chemoattractant activity(GO:0042056)
0.1 0.5 GO:0045545 syndecan binding(GO:0045545)
0.1 0.6 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 1.2 GO:0016918 retinal binding(GO:0016918)
0.1 1.6 GO:0005112 Notch binding(GO:0005112)
0.1 6.6 GO:0030165 PDZ domain binding(GO:0030165)
0.1 0.5 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 11.8 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 0.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 65.5 GO:0005509 calcium ion binding(GO:0005509)
0.1 1.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.8 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.1 1.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.6 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 1.1 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 1.7 GO:0019865 immunoglobulin binding(GO:0019865)
0.1 0.3 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 0.4 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 1.2 GO:0001055 RNA polymerase II activity(GO:0001055)
0.1 0.7 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.1 0.2 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403) uptake transmembrane transporter activity(GO:0015563)
0.1 0.4 GO:0050733 RS domain binding(GO:0050733)
0.1 0.7 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 9.9 GO:0051015 actin filament binding(GO:0051015)
0.1 0.6 GO:0036310 annealing helicase activity(GO:0036310)
0.1 3.7 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 0.2 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.0 0.4 GO:0031995 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 0.3 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 1.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 5.0 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.6 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.8 GO:0030552 cAMP binding(GO:0030552)
0.0 0.3 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.5 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.9 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.0 2.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.4 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 1.0 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 1.0 GO:0070330 aromatase activity(GO:0070330)
0.0 1.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.4 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.7 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.5 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.1 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.2 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 1.0 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 1.1 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.6 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.0 1.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.7 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 1.2 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.2 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 1.2 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 2.3 GO:0035064 methylated histone binding(GO:0035064)
0.0 1.3 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.7 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0019144 ADP-sugar diphosphatase activity(GO:0019144)
0.0 0.5 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083) transcription factor activity, TFIIB-class binding(GO:0001087) TFIIB-class transcription factor binding(GO:0001093)
0.0 6.4 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.2 GO:0051766 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 0.2 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.6 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.3 GO:0004630 phospholipase D activity(GO:0004630) N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.3 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.8 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.1 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 1.8 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 4.8 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.4 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.5 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 2.9 GO:0101005 ubiquitinyl hydrolase activity(GO:0101005)
0.0 2.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 10.8 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 2.1 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.6 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.1 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.1 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.6 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.5 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.0 GO:0016768 spermine synthase activity(GO:0016768)
0.0 0.2 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 1.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.6 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.3 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.2 GO:0043047 single-stranded telomeric DNA binding(GO:0043047) G-rich strand telomeric DNA binding(GO:0098505)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 21.7 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.3 11.9 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2 0.7 PID REELIN PATHWAY Reelin signaling pathway
0.2 2.9 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.2 12.9 PID ATR PATHWAY ATR signaling pathway
0.2 20.0 PID LKB1 PATHWAY LKB1 signaling events
0.1 0.4 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 6.7 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 15.1 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.1 3.7 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 4.0 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 7.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 16.9 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 8.1 PID BMP PATHWAY BMP receptor signaling
0.1 2.9 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 3.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 3.1 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 4.0 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 0.7 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 1.7 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 1.8 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 2.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 0.6 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 2.1 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 1.2 ST GAQ PATHWAY G alpha q Pathway
0.0 1.0 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 3.5 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 2.3 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 1.3 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.9 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.7 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 1.2 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.3 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.1 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 1.1 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.2 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.4 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.1 PID CD40 PATHWAY CD40/CD40L signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.8 30.1 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.5 7.7 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.4 15.8 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.4 10.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.3 8.9 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.3 11.3 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.3 5.7 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.3 12.9 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.2 0.5 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.2 3.8 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.2 11.1 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.2 3.9 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.2 3.8 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.2 8.2 REACTOME KINESINS Genes involved in Kinesins
0.2 11.2 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.2 4.8 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 6.3 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.2 8.0 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 3.9 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.2 0.9 REACTOME SIGNALING BY FGFR Genes involved in Signaling by FGFR
0.1 5.4 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.1 6.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 4.7 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 3.3 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 3.8 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.1 1.5 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 2.7 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.1 0.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 7.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 2.1 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.1 0.9 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.1 0.8 REACTOME ION CHANNEL TRANSPORT Genes involved in Ion channel transport
0.1 1.6 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 1.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 5.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 1.6 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.1 2.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 1.8 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.1 1.6 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 9.7 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.1 1.2 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.1 2.5 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.1 0.9 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.1 2.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 1.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 2.1 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 2.4 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.1 2.7 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.1 4.2 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 3.0 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.1 1.8 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 1.5 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 2.8 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 3.7 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.1 0.8 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 2.7 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 2.4 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.1 1.9 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 3.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 1.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 2.0 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.9 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 0.4 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 1.1 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 1.7 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.4 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.6 REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND Genes involved in Processive synthesis on the lagging strand
0.0 0.3 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 4.7 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.7 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 2.5 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.8 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.4 REACTOME OPSINS Genes involved in Opsins
0.0 0.3 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 1.0 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.0 0.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.5 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 2.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 2.0 REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES Genes involved in Transmission across Chemical Synapses
0.0 0.3 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 1.9 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 4.6 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 1.8 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.6 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.5 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.1 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.6 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization