ISMARA results: SOX7

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Illumina Body Map 2: averaged replicates

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Results for SOX7

Z-value: 1.25

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Transcription factors associated with SOX7

Gene Symbol	Gene ID	Gene Info
SOX7 Ensembl NCBI GeneCards UniProt NextProt	ENSG00000171056.6	SRY-box transcription factor 7
SOX7 Ensembl NCBI GeneCards UniProt NextProt	ENSG00000258724.1	SRY-box transcription factor 7

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
SOX7	hg19_v2_chr8_-_10697281_10697365	-0.39	2.8e-02	Click!

Activity profile of SOX7 motif

Sorted Z-values of SOX7 motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr16_-_20364030 Show fit	7.19	ENST00000396134.2 ENST00000573567.1 ENST00000570757.1 ENST00000424589.1 ENST00000302509.4 ENST00000571174.1 ENST00000576688.1	UMOD Ensembl NCBI GeneCards UniProt NextProt Show fit	uromodulin
chr16_-_20364122 Show fit	6.29	ENST00000396138.4 ENST00000577168.1	UMOD Ensembl NCBI GeneCards UniProt NextProt Show fit	uromodulin
chr1_-_26394114 Show fit	4.68	ENST00000374272.3	TRIM63 Ensembl NCBI GeneCards UniProt NextProt Show fit	tripartite motif containing 63, E3 ubiquitin protein ligase
chr4_-_177190364 Show fit	3.35	ENST00000296525.3	ASB5 Ensembl NCBI GeneCards UniProt NextProt Show fit	ankyrin repeat and SOCS box containing 5
chr6_-_46048116 Show fit	2.14	ENST00000185206.6	CLIC5 Ensembl NCBI GeneCards UniProt NextProt Show fit	chloride intracellular channel 5
chr10_-_61495760 Show fit	2.14	ENST00000395347.1	SLC16A9 Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 16, member 9
chr4_+_76995855 Show fit	1.73	ENST00000355810.4 ENST00000349321.3	ART3 Ensembl NCBI GeneCards UniProt NextProt Show fit	ADP-ribosyltransferase 3
chr1_-_186430222 Show fit	1.58	ENST00000391997.2	PDC Ensembl NCBI GeneCards UniProt NextProt Show fit	phosducin
chr1_-_43751276 Show fit	1.43	ENST00000423420.1	C1orf210 Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 1 open reading frame 210
chr6_+_150690089 Show fit	1.36	ENST00000392256.2	IYD Ensembl NCBI GeneCards UniProt NextProt Show fit	iodotyrosine deiodinase

Showing 1 to 10 of 85 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX7

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
2.7	13.5	GO:0072023	thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
0.9	4.7	GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.2	3.4	GO:0006570	tyrosine metabolic process(GO:0006570)
0.3	2.1	GO:0009753	response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.1	2.1	GO:0060088	auditory receptor cell stereocilium organization(GO:0060088)
0.1	2.1	GO:0046415	urate metabolic process(GO:0046415)
0.1	2.0	GO:0045838	positive regulation of membrane potential(GO:0045838)
0.0	1.7	GO:0006471	protein ADP-ribosylation(GO:0006471)
0.3	1.6	GO:0046116	queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1	1.2	GO:0030259	lipid glycosylation(GO:0030259)

Showing 1 to 10 of 27 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	14.6	GO:0060170	ciliary membrane(GO:0060170)
0.1	4.7	GO:0031430	M band(GO:0031430)
0.0	1.6	GO:0001917	photoreceptor inner segment(GO:0001917)
0.0	1.2	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.3	1.1	GO:0036024	protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.0	0.6	GO:0097546	ciliary base(GO:0097546)
0.0	0.5	GO:0005687	U4 snRNP(GO:0005687)
0.1	0.4	GO:0034448	EGO complex(GO:0034448)
0.0	0.3	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
0.0	0.2	GO:0005785	signal recognition particle receptor complex(GO:0005785)

Showing 1 to 10 of 10 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.7	13.5	GO:0019864	IgG binding(GO:0019864)
0.2	4.7	GO:0031432	titin binding(GO:0031432)
0.5	3.4	GO:0004447	iodide peroxidase activity(GO:0004447)
0.3	2.1	GO:0018636	phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.0	2.1	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	2.1	GO:0008028	monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1	2.0	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.2	1.7	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.3	1.6	GO:0008479	queuine tRNA-ribosyltransferase activity(GO:0008479)
0.2	1.2	GO:0003947	(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity(GO:0003947)

Showing 1 to 10 of 25 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.1	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods

Showing 1 to 1 of 1 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	7.7	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1	3.4	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	2.0	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.9	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.7	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.4	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1

Showing 1 to 6 of 6 entries

Results for SOX7

Z-value: 1.25

Motif logo

Transcription factors associated with SOX7

Activity-expression correlation:

Activity profile of SOX7 motif

Sorted Z-values of SOX7 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX7

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: