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Illumina Body Map 2: averaged replicates

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Results for SOX8

Z-value: 1.86

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Transcription factors associated with SOX8

Gene Symbol Gene ID Gene Info
SOX8
ENSG00000005513.9 SRY-box transcription factor 8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX8hg19_v2_chr16_+_1031762_10318080.649.1e-05Click!

Activity profile of SOX8 motif

Sorted Z-values of SOX8 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr22_-_50523843 4.41 ENST00000535444.1
ENST00000431262.2
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr2_-_175711133 3.56 ENST00000409597.1
ENST00000413882.1
CHN1
chimerin 1
chr22_-_50523688 3.45 ENST00000450140.2
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr5_+_156887027 3.12 ENST00000435489.2
ENST00000311946.7
NIPAL4
NIPA-like domain containing 4
chr8_-_82359662 3.01 ENST00000519260.1
ENST00000256103.2
PMP2
peripheral myelin protein 2
chr2_+_26624775 2.96 ENST00000288710.2
DRC1
dynein regulatory complex subunit 1 homolog (Chlamydomonas)
chr4_-_176828307 2.74 ENST00000513365.1
ENST00000513667.1
ENST00000503563.1
GPM6A
glycoprotein M6A
chr2_+_173792893 2.72 ENST00000535187.1
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr22_-_50523760 2.50 ENST00000395876.2
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr16_+_87636474 2.47 ENST00000284262.2
JPH3
junctophilin 3
chr14_+_22337014 2.44 ENST00000390436.2
TRAV13-1
T cell receptor alpha variable 13-1
chr22_-_50523807 2.33 ENST00000442311.1
ENST00000538737.1
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr5_+_175288631 2.31 ENST00000509837.1
CPLX2
complexin 2
chr1_-_200992827 2.21 ENST00000332129.2
ENST00000422435.2
KIF21B
kinesin family member 21B
chr2_+_13677795 2.05 ENST00000434509.1
AC092635.1
AC092635.1
chr5_-_160279207 2.02 ENST00000327245.5
ATP10B
ATPase, class V, type 10B
chr7_-_38289173 2.01 ENST00000436911.2
TRGC2
T cell receptor gamma constant 2
chr18_-_3845321 1.99 ENST00000539435.1
ENST00000400147.2
DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chrX_+_18725758 1.96 ENST00000472826.1
ENST00000544635.1
ENST00000496075.2
PPEF1
protein phosphatase, EF-hand calcium binding domain 1
chr1_+_66820058 1.94 ENST00000480109.2
PDE4B
phosphodiesterase 4B, cAMP-specific
chr3_-_193272741 1.92 ENST00000392443.3
ATP13A4
ATPase type 13A4
chr14_+_58797974 1.87 ENST00000417477.2
ARID4A
AT rich interactive domain 4A (RBP1-like)
chr8_-_86253888 1.83 ENST00000522389.1
ENST00000432364.2
ENST00000517618.1
CA1
carbonic anhydrase I
chr12_-_10282742 1.75 ENST00000298523.5
ENST00000396484.2
ENST00000310002.4
CLEC7A
C-type lectin domain family 7, member A
chr20_+_58203664 1.73 ENST00000541461.1
PHACTR3
phosphatase and actin regulator 3
chr7_+_36450169 1.69 ENST00000428612.1
ANLN
anillin, actin binding protein
chr9_-_113761720 1.69 ENST00000541779.1
ENST00000374430.2
LPAR1
lysophosphatidic acid receptor 1
chr1_+_153330322 1.63 ENST00000368738.3
S100A9
S100 calcium binding protein A9
chr5_-_160973649 1.61 ENST00000393959.1
ENST00000517547.1
GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2
chr6_+_80129989 1.60 ENST00000429444.1
RP1-232L24.3
RP1-232L24.3
chr18_-_3845293 1.58 ENST00000400145.2
DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chr2_-_70944855 1.57 ENST00000415348.1
ADD2
adducin 2 (beta)
chr18_-_5396271 1.55 ENST00000579951.1
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr3_-_167191814 1.54 ENST00000466903.1
ENST00000264677.4
SERPINI2
serpin peptidase inhibitor, clade I (pancpin), member 2
chr12_-_11548496 1.53 ENST00000389362.4
ENST00000565533.1
ENST00000546254.1
PRB2
PRB1
proline-rich protein BstNI subfamily 2
proline-rich protein BstNI subfamily 1
chr3_-_193272588 1.52 ENST00000295548.3
ATP13A4
ATPase type 13A4
chr15_-_89755034 1.48 ENST00000563254.1
RLBP1
retinaldehyde binding protein 1
chr12_-_120241187 1.48 ENST00000392520.2
CIT
citron (rho-interacting, serine/threonine kinase 21)
chrX_+_100474906 1.46 ENST00000541709.1
DRP2
dystrophin related protein 2
chr12_-_10282681 1.42 ENST00000533022.1
CLEC7A
C-type lectin domain family 7, member A
chr2_+_7118755 1.42 ENST00000433456.1
RNF144A
ring finger protein 144A
chr16_-_30122717 1.41 ENST00000566613.1
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr12_-_10282836 1.41 ENST00000304084.8
ENST00000353231.5
ENST00000525605.1
CLEC7A
C-type lectin domain family 7, member A
chr18_-_29264467 1.39 ENST00000383131.3
ENST00000237019.7
B4GALT6
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
chr5_-_94417186 1.38 ENST00000312216.8
ENST00000512425.1
MCTP1
multiple C2 domains, transmembrane 1
chr4_-_21699380 1.34 ENST00000382148.3
KCNIP4
Kv channel interacting protein 4
chr14_+_52327350 1.34 ENST00000555472.1
ENST00000556766.1
GNG2
guanine nucleotide binding protein (G protein), gamma 2
chr12_+_79371565 1.33 ENST00000551304.1
SYT1
synaptotagmin I
chr18_+_56892724 1.33 ENST00000456142.3
ENST00000530323.1
GRP
gastrin-releasing peptide
chr1_+_87012753 1.33 ENST00000370563.3
CLCA4
chloride channel accessory 4
chr19_-_46999755 1.31 ENST00000599531.1
PNMAL2
paraneoplastic Ma antigen family-like 2
chr13_-_47012325 1.31 ENST00000409879.2
KIAA0226L
KIAA0226-like
chr16_+_14280564 1.30 ENST00000572567.1
MKL2
MKL/myocardin-like 2
chr1_+_38512799 1.29 ENST00000432922.1
ENST00000428151.1
RP5-884C9.2
RP5-884C9.2
chr5_-_94417314 1.29 ENST00000505208.1
MCTP1
multiple C2 domains, transmembrane 1
chr2_+_204801471 1.27 ENST00000316386.6
ENST00000435193.1
ICOS
inducible T-cell co-stimulator
chr14_+_22580233 1.27 ENST00000390454.2
TRAV25
T cell receptor alpha variable 25
chr14_-_106471723 1.27 ENST00000390595.2
IGHV1-3
immunoglobulin heavy variable 1-3
chr3_+_35683816 1.26 ENST00000438577.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr12_+_29376673 1.25 ENST00000547116.1
FAR2
fatty acyl CoA reductase 2
chr21_+_22519416 1.25 ENST00000535285.1
NCAM2
neural cell adhesion molecule 2
chr7_-_14942283 1.25 ENST00000402815.1
DGKB
diacylglycerol kinase, beta 90kDa
chr1_+_158901329 1.24 ENST00000368140.1
ENST00000368138.3
ENST00000392254.2
ENST00000392252.3
ENST00000368135.4
PYHIN1
pyrin and HIN domain family, member 1
chr5_-_94417339 1.22 ENST00000429576.2
ENST00000508509.1
ENST00000510732.1
MCTP1
multiple C2 domains, transmembrane 1
chr8_-_120605194 1.22 ENST00000522167.1
ENPP2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr10_-_49482907 1.19 ENST00000374201.3
ENST00000407470.4
FRMPD2
FERM and PDZ domain containing 2
chr15_+_81299370 1.17 ENST00000560091.1
C15orf26
chromosome 15 open reading frame 26
chr4_+_159131596 1.16 ENST00000512481.1
TMEM144
transmembrane protein 144
chr1_-_111148241 1.15 ENST00000440270.1
KCNA2
potassium voltage-gated channel, shaker-related subfamily, member 2
chr5_+_140186647 1.14 ENST00000512229.2
ENST00000356878.4
ENST00000530339.1
PCDHA4
protocadherin alpha 4
chr3_-_39322728 1.13 ENST00000541347.1
ENST00000412814.1
CX3CR1
chemokine (C-X3-C motif) receptor 1
chr4_-_144826682 1.13 ENST00000358615.4
ENST00000437468.2
GYPE
glycophorin E (MNS blood group)
chr10_-_1779663 1.11 ENST00000381312.1
ADARB2
adenosine deaminase, RNA-specific, B2 (non-functional)
chr5_+_140227048 1.10 ENST00000532602.1
PCDHA9
protocadherin alpha 9
chr14_+_23001452 1.10 ENST00000390526.1
TRAJ11
T cell receptor alpha joining 11
chr4_-_144940477 1.10 ENST00000513128.1
ENST00000429670.2
ENST00000502664.1
GYPB
glycophorin B (MNS blood group)
chr16_-_65106110 1.09 ENST00000562882.1
ENST00000567934.1
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr8_+_38244638 1.08 ENST00000526356.1
LETM2
leucine zipper-EF-hand containing transmembrane protein 2
chr2_-_36779411 1.07 ENST00000406220.1
AC007401.2
Uncharacterized protein
chr11_+_128563652 1.05 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr15_+_43985084 1.05 ENST00000434505.1
ENST00000411750.1
CKMT1A
creatine kinase, mitochondrial 1A
chr2_-_214017151 1.05 ENST00000452786.1
IKZF2
IKAROS family zinc finger 2 (Helios)
chr2_-_158485387 1.03 ENST00000243349.8
ACVR1C
activin A receptor, type IC
chr11_-_125366089 1.03 ENST00000366139.3
ENST00000278919.3
FEZ1
fasciculation and elongation protein zeta 1 (zygin I)
chrX_-_75005054 1.02 ENST00000373359.2
MAGEE2
melanoma antigen family E, 2
chr12_+_29376592 1.02 ENST00000182377.4
FAR2
fatty acyl CoA reductase 2
chr12_+_20848377 1.02 ENST00000540354.1
ENST00000266509.2
ENST00000381552.1
SLCO1C1
solute carrier organic anion transporter family, member 1C1
chr14_+_75745477 1.02 ENST00000303562.4
ENST00000554617.1
ENST00000554212.1
ENST00000535987.1
ENST00000555242.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr16_+_31271274 1.01 ENST00000287497.8
ENST00000544665.3
ITGAM
integrin, alpha M (complement component 3 receptor 3 subunit)
chr17_-_8021710 1.00 ENST00000380149.1
ENST00000448843.2
ALOXE3
arachidonate lipoxygenase 3
chr6_-_32160622 1.00 ENST00000487761.1
ENST00000375040.3
GPSM3
G-protein signaling modulator 3
chr2_+_7073174 0.99 ENST00000416587.1
RNF144A
ring finger protein 144A
chr15_+_43885252 0.98 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
CKMT1B
creatine kinase, mitochondrial 1B
chr12_-_11508520 0.96 ENST00000545626.1
ENST00000500254.2
PRB1
proline-rich protein BstNI subfamily 1
chr11_-_41481135 0.96 ENST00000528697.1
ENST00000530763.1
LRRC4C
leucine rich repeat containing 4C
chr6_+_12718497 0.96 ENST00000379348.2
PHACTR1
phosphatase and actin regulator 1
chr14_-_106642049 0.95 ENST00000390605.2
IGHV1-18
immunoglobulin heavy variable 1-18
chr1_+_8378140 0.94 ENST00000377479.2
SLC45A1
solute carrier family 45, member 1
chr11_-_83878041 0.93 ENST00000398299.1
DLG2
discs, large homolog 2 (Drosophila)
chr1_+_161475208 0.93 ENST00000367972.4
ENST00000271450.6
FCGR2A
Fc fragment of IgG, low affinity IIa, receptor (CD32)
chr1_-_183538319 0.92 ENST00000420553.1
ENST00000419402.1
NCF2
neutrophil cytosolic factor 2
chr10_-_87551311 0.92 ENST00000536331.1
GRID1
glutamate receptor, ionotropic, delta 1
chr4_-_38858428 0.92 ENST00000436693.2
ENST00000508254.1
ENST00000514655.1
ENST00000506146.1
TLR6
TLR1
toll-like receptor 6
toll-like receptor 1
chr18_-_29264669 0.91 ENST00000306851.5
B4GALT6
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
chr4_+_156680143 0.90 ENST00000505154.1
GUCY1B3
guanylate cyclase 1, soluble, beta 3
chr15_+_77861183 0.90 ENST00000560590.1
ENST00000561123.1
RP11-307C19.2
RP11-307C19.2
chr17_-_16918271 0.90 ENST00000562897.1
RP11-416I2.1
RP11-416I2.1
chr6_+_73076432 0.90 ENST00000414192.2
RIMS1
regulating synaptic membrane exocytosis 1
chr12_+_126107042 0.89 ENST00000535886.1
TMEM132B
transmembrane protein 132B
chr8_-_11873043 0.89 ENST00000527396.1
RP11-481A20.11
Protein LOC101060662
chr12_+_56325812 0.87 ENST00000394147.1
ENST00000551156.1
ENST00000553783.1
ENST00000557080.1
ENST00000432422.3
ENST00000556001.1
DGKA
diacylglycerol kinase, alpha 80kDa
chr22_-_30642728 0.86 ENST00000403987.3
LIF
leukemia inhibitory factor
chr3_+_147657764 0.86 ENST00000467198.1
ENST00000485006.1
RP11-71N10.1
RP11-71N10.1
chr3_+_35683651 0.86 ENST00000187397.4
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr18_-_53253323 0.84 ENST00000540999.1
ENST00000563888.2
TCF4
transcription factor 4
chr12_-_95010147 0.84 ENST00000548918.1
TMCC3
transmembrane and coiled-coil domain family 3
chr3_+_113465866 0.84 ENST00000273398.3
ENST00000538620.1
ENST00000496747.1
ENST00000475322.1
ATP6V1A
ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr3_+_157154578 0.84 ENST00000295927.3
PTX3
pentraxin 3, long
chr4_+_40192656 0.84 ENST00000505618.1
RHOH
ras homolog family member H
chr11_-_112131312 0.84 ENST00000527122.1
C11orf34
placenta expressed transcript 1
chr15_+_34261089 0.84 ENST00000383263.5
CHRM5
cholinergic receptor, muscarinic 5
chr14_-_106967788 0.84 ENST00000390622.2
IGHV1-46
immunoglobulin heavy variable 1-46
chr12_+_20848282 0.83 ENST00000545604.1
SLCO1C1
solute carrier organic anion transporter family, member 1C1
chr12_-_50101003 0.83 ENST00000550488.1
FMNL3
formin-like 3
chr12_-_123201337 0.83 ENST00000528880.2
HCAR3
hydroxycarboxylic acid receptor 3
chr4_-_145061788 0.82 ENST00000512064.1
ENST00000512789.1
ENST00000504786.1
ENST00000503627.1
ENST00000535709.1
ENST00000324022.10
ENST00000360771.4
ENST00000283126.7
GYPA
GYPB
glycophorin A (MNS blood group)
glycophorin B (MNS blood group)
chr3_+_35683775 0.81 ENST00000452563.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr3_+_137906154 0.80 ENST00000466749.1
ENST00000358441.2
ENST00000489213.1
ARMC8
armadillo repeat containing 8
chr18_-_5577640 0.79 ENST00000582592.1
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr4_+_156680153 0.78 ENST00000502959.1
ENST00000505764.1
ENST00000507146.1
ENST00000264424.8
ENST00000503520.1
GUCY1B3
guanylate cyclase 1, soluble, beta 3
chr3_-_21792838 0.78 ENST00000281523.2
ZNF385D
zinc finger protein 385D
chr6_-_133079022 0.77 ENST00000525289.1
ENST00000326499.6
VNN2
vanin 2
chr22_-_20255212 0.77 ENST00000416372.1
RTN4R
reticulon 4 receptor
chr1_-_116383738 0.77 ENST00000320238.3
NHLH2
nescient helix loop helix 2
chr8_+_35649365 0.76 ENST00000437887.1
AC012215.1
Uncharacterized protein
chr5_-_132948216 0.75 ENST00000265342.7
FSTL4
follistatin-like 4
chr16_+_14280742 0.75 ENST00000341243.5
MKL2
MKL/myocardin-like 2
chr6_+_148593425 0.75 ENST00000367469.1
SASH1
SAM and SH3 domain containing 1
chr1_-_120354079 0.75 ENST00000354219.1
ENST00000369401.4
ENST00000256585.5
REG4
regenerating islet-derived family, member 4
chr17_-_34207295 0.74 ENST00000463941.1
ENST00000293272.3
CCL5
chemokine (C-C motif) ligand 5
chr10_-_128110441 0.74 ENST00000456514.1
LINC00601
long intergenic non-protein coding RNA 601
chr7_-_36634181 0.74 ENST00000538464.1
AOAH
acyloxyacyl hydrolase (neutrophil)
chr1_-_9811600 0.74 ENST00000435891.1
CLSTN1
calsyntenin 1
chr4_-_88450511 0.74 ENST00000458304.2
SPARCL1
SPARC-like 1 (hevin)
chr12_-_50101165 0.74 ENST00000352151.5
ENST00000335154.5
ENST00000293590.5
FMNL3
formin-like 3
chr20_-_1472029 0.73 ENST00000359801.3
SIRPB2
signal-regulatory protein beta 2
chr15_+_77308152 0.73 ENST00000559859.1
PSTPIP1
proline-serine-threonine phosphatase interacting protein 1
chr7_+_142012967 0.72 ENST00000390357.3
TRBV4-1
T cell receptor beta variable 4-1
chr12_-_39837192 0.71 ENST00000361961.3
ENST00000395670.3
KIF21A
kinesin family member 21A
chr6_+_37012607 0.71 ENST00000423336.1
COX6A1P2
cytochrome c oxidase subunit VIa polypeptide 1 pseudogene 2
chr12_+_65277536 0.71 ENST00000540024.1
RP11-766N7.3
RP11-766N7.3
chr8_-_126963487 0.70 ENST00000518964.1
LINC00861
long intergenic non-protein coding RNA 861
chr17_-_19648683 0.70 ENST00000573368.1
ENST00000457500.2
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr1_-_153029980 0.70 ENST00000392653.2
SPRR2A
small proline-rich protein 2A
chr14_-_101053739 0.69 ENST00000554140.1
BEGAIN
brain-enriched guanylate kinase-associated
chr18_-_53253112 0.69 ENST00000568673.1
ENST00000562847.1
ENST00000568147.1
TCF4
transcription factor 4
chr4_-_100356551 0.69 ENST00000209665.4
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr7_+_142919130 0.69 ENST00000408947.3
TAS2R40
taste receptor, type 2, member 40
chr2_-_211342292 0.68 ENST00000448951.1
LANCL1
LanC lantibiotic synthetase component C-like 1 (bacterial)
chr18_+_61575200 0.68 ENST00000238508.3
SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr12_-_76879852 0.67 ENST00000548341.1
OSBPL8
oxysterol binding protein-like 8
chr2_+_102413726 0.67 ENST00000350878.4
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr6_-_30899924 0.66 ENST00000359086.3
SFTA2
surfactant associated 2
chr1_-_38512450 0.66 ENST00000373012.2
POU3F1
POU class 3 homeobox 1
chr22_-_50708781 0.66 ENST00000449719.2
ENST00000330651.6
MAPK11
mitogen-activated protein kinase 11
chr12_-_123187890 0.66 ENST00000328880.5
HCAR2
hydroxycarboxylic acid receptor 2
chr1_+_111415757 0.65 ENST00000429072.2
ENST00000271324.5
CD53
CD53 molecule
chr12_-_57443886 0.65 ENST00000300119.3
MYO1A
myosin IA
chr2_-_163008903 0.65 ENST00000418842.2
ENST00000375497.3
GCG
glucagon
chr7_-_80551671 0.64 ENST00000419255.2
ENST00000544525.1
SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr18_-_53253000 0.64 ENST00000566514.1
TCF4
transcription factor 4
chr4_-_69434245 0.64 ENST00000317746.2
UGT2B17
UDP glucuronosyltransferase 2 family, polypeptide B17
chrX_+_15767971 0.64 ENST00000479740.1
ENST00000454127.2
CA5B
carbonic anhydrase VB, mitochondrial
chr15_+_45879964 0.64 ENST00000565409.1
ENST00000564765.1
BLOC1S6
biogenesis of lysosomal organelles complex-1, subunit 6, pallidin
chr14_+_88471468 0.63 ENST00000267549.3
GPR65
G protein-coupled receptor 65
chr7_-_64467031 0.63 ENST00000394323.2
ERV3-1
endogenous retrovirus group 3, member 1
chr11_-_128457446 0.63 ENST00000392668.4
ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
chr6_-_116833500 0.62 ENST00000356128.4
TRAPPC3L
trafficking protein particle complex 3-like
chr6_-_136788001 0.62 ENST00000544465.1
MAP7
microtubule-associated protein 7
chr7_+_139478030 0.61 ENST00000425687.1
ENST00000263552.6
ENST00000438104.1
ENST00000336425.5
TBXAS1
thromboxane A synthase 1 (platelet)
chr16_+_57769635 0.61 ENST00000379661.3
ENST00000562592.1
ENST00000566726.1
KATNB1
katanin p80 (WD repeat containing) subunit B 1
chr19_+_18794470 0.60 ENST00000321949.8
ENST00000338797.6
CRTC1
CREB regulated transcription coactivator 1
chr2_-_187367356 0.60 ENST00000595956.1
AC018867.2
AC018867.2
chr19_+_1269324 0.60 ENST00000589710.1
ENST00000588230.1
ENST00000413636.2
ENST00000586472.1
ENST00000589686.1
ENST00000444172.2
ENST00000587323.1
ENST00000320936.5
ENST00000587896.1
ENST00000589235.1
ENST00000591659.1
CIRBP
cold inducible RNA binding protein
chr11_-_129062093 0.59 ENST00000310343.9
ARHGAP32
Rho GTPase activating protein 32
chr15_+_78830023 0.59 ENST00000599596.1
AC027228.1
HCG2005369; Uncharacterized protein
chr20_+_42543504 0.59 ENST00000341197.4
TOX2
TOX high mobility group box family member 2
chr6_+_147527103 0.58 ENST00000179882.6
STXBP5
syntaxin binding protein 5 (tomosyn)
chrX_-_50386648 0.58 ENST00000460112.3
SHROOM4
shroom family member 4
chr6_-_10115007 0.58 ENST00000485268.1
OFCC1
orofacial cleft 1 candidate 1
chr6_+_31021225 0.58 ENST00000565192.1
ENST00000562344.1
HCG22
HLA complex group 22
chr8_+_30496078 0.56 ENST00000517349.1
SMIM18
small integral membrane protein 18
chr8_+_21915368 0.56 ENST00000265800.5
ENST00000517418.1
DMTN
dematin actin binding protein
chr12_-_10007448 0.56 ENST00000538152.1
CLEC2B
C-type lectin domain family 2, member B
chr20_-_1472053 0.55 ENST00000537284.1
SIRPB2
signal-regulatory protein beta 2
chr8_-_126963417 0.54 ENST00000500989.2
LINC00861
long intergenic non-protein coding RNA 861
chr14_+_23000889 0.53 ENST00000390525.1
TRAJ12
T cell receptor alpha joining 12
chr10_-_38265517 0.53 ENST00000302609.7
ZNF25
zinc finger protein 25
chr2_-_239140011 0.52 ENST00000409376.1
ENST00000409070.1
ENST00000409942.1
AC016757.3
Protein LOC151174
chr6_-_138539627 0.51 ENST00000527246.2
PBOV1
prostate and breast cancer overexpressed 1

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 12.7 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.6 1.7 GO:0031106 septin ring assembly(GO:0000921) septin ring organization(GO:0031106)
0.5 1.6 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.4 1.1 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.3 1.0 GO:1901383 negative regulation of chorionic trophoblast cell proliferation(GO:1901383)
0.3 1.7 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.3 1.9 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.3 0.9 GO:0034130 toll-like receptor 1 signaling pathway(GO:0034130)
0.3 2.3 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.3 0.8 GO:0060304 regulation of phosphatidylinositol dephosphorylation(GO:0060304)
0.3 1.3 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.3 0.8 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.2 0.9 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.2 1.3 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.2 1.7 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.2 4.6 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.2 0.6 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.2 0.6 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.2 3.1 GO:0015693 magnesium ion transport(GO:0015693)
0.2 1.1 GO:0021633 optic nerve structural organization(GO:0021633)
0.2 0.7 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.2 2.3 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.2 0.9 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 1.9 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.6 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.1 1.9 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.6 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 1.0 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 0.8 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.1 0.5 GO:0010585 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.1 1.0 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 0.7 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.1 0.7 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.1 0.4 GO:0097115 cytoskeletal matrix organization at active zone(GO:0048789) neurexin clustering involved in presynaptic membrane assembly(GO:0097115) retrograde trans-synaptic signaling by trans-synaptic protein complex(GO:0098942)
0.1 0.3 GO:0006174 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.1 0.7 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.1 3.0 GO:0060285 cilium-dependent cell motility(GO:0060285)
0.1 0.3 GO:1903056 regulation of melanosome organization(GO:1903056)
0.1 0.3 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.1 1.1 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.1 2.3 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.1 0.3 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 0.6 GO:0071461 cellular response to redox state(GO:0071461)
0.1 0.6 GO:0030578 PML body organization(GO:0030578)
0.1 0.3 GO:0045209 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.1 0.7 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.1 1.7 GO:0071420 cellular response to histamine(GO:0071420)
0.1 1.2 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.3 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 0.7 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.1 3.6 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 1.1 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.1 1.0 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.1 0.3 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.1 1.0 GO:0006600 creatine metabolic process(GO:0006600)
0.1 2.0 GO:0045332 phospholipid translocation(GO:0045332)
0.1 1.1 GO:0002517 T cell tolerance induction(GO:0002517)
0.1 0.4 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 0.5 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.1 0.3 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.1 0.6 GO:0070560 protein secretion by platelet(GO:0070560)
0.1 0.2 GO:1904106 protein localization to microvillus(GO:1904106)
0.1 0.9 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.1 1.6 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 0.7 GO:0016081 synaptic vesicle docking(GO:0016081)
0.1 2.5 GO:0035640 exploration behavior(GO:0035640)
0.1 2.4 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.1 1.0 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.8 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.6 GO:0060613 fat pad development(GO:0060613)
0.0 0.5 GO:0018406 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 1.6 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.8 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.8 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 1.4 GO:0035855 megakaryocyte development(GO:0035855)
0.0 2.5 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.5 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 2.6 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.5 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0001172 transcription, RNA-templated(GO:0001172)
0.0 1.2 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.2 GO:0031296 positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296)
0.0 0.4 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.8 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.8 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 1.3 GO:0030033 microvillus assembly(GO:0030033)
0.0 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.8 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 0.4 GO:0021559 trigeminal nerve development(GO:0021559)
0.0 0.4 GO:0002860 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.2 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 1.6 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 2.7 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.6 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.2 GO:0046373 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.5 GO:1903817 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 0.7 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.3 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.2 GO:0006196 AMP catabolic process(GO:0006196)
0.0 2.0 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.0 1.5 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.9 GO:0045730 respiratory burst(GO:0045730)
0.0 0.3 GO:0003096 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.0 0.8 GO:0044705 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0 0.3 GO:0070269 pyroptosis(GO:0070269)
0.0 0.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.6 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.3 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 1.0 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.5 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.1 GO:0052361 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.0 0.2 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.9 GO:0035176 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0 1.2 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.4 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.1 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.0 0.2 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
0.0 0.4 GO:0035588 G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.6 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.4 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.4 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.7 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.3 GO:0002347 response to tumor cell(GO:0002347)
0.0 0.5 GO:0044458 motile cilium assembly(GO:0044458)
0.0 2.0 GO:0048636 positive regulation of striated muscle tissue development(GO:0045844) positive regulation of muscle organ development(GO:0048636)
0.0 0.2 GO:1903416 negative regulation of glucocorticoid metabolic process(GO:0031944) negative regulation of glucocorticoid biosynthetic process(GO:0031947) negative regulation of steroid hormone biosynthetic process(GO:0090032) response to glycoside(GO:1903416)
0.0 2.4 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.2 GO:0030866 cortical cytoskeleton organization(GO:0030865) cortical actin cytoskeleton organization(GO:0030866)
0.0 0.1 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.2 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.5 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:0061314 Notch signaling involved in heart development(GO:0061314)
0.0 3.0 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.0 2.9 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.3 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 3.1 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 2.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.3 GO:0050974 detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.0 1.8 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.3 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 1.1 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0048179 activin receptor complex(GO:0048179)
0.2 2.3 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.2 0.9 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.2 1.7 GO:0005826 actomyosin contractile ring(GO:0005826)
0.2 2.5 GO:0030314 junctional membrane complex(GO:0030314)
0.1 1.3 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 0.5 GO:0097224 sperm connecting piece(GO:0097224)
0.1 1.0 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.1 0.6 GO:0036338 viral envelope(GO:0019031) viral membrane(GO:0036338)
0.1 1.0 GO:0035976 AP1 complex(GO:0035976)
0.1 4.9 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 0.9 GO:0032010 phagolysosome(GO:0032010)
0.1 3.5 GO:0044295 axonal growth cone(GO:0044295)
0.1 1.6 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 11.9 GO:0005901 caveola(GO:0005901)
0.1 0.3 GO:0071942 XPC complex(GO:0071942)
0.1 2.3 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 1.9 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 0.8 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 2.8 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 1.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.5 GO:0036128 CatSper complex(GO:0036128)
0.0 1.6 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.7 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.7 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.7 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 1.1 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 2.9 GO:0005871 kinesin complex(GO:0005871)
0.0 0.6 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.3 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.5 GO:0033391 chromatoid body(GO:0033391)
0.0 0.4 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.2 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 2.1 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.6 GO:0001772 immunological synapse(GO:0001772)
0.0 1.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.3 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 7.9 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.3 GO:0008091 spectrin(GO:0008091)
0.0 0.4 GO:0000815 ESCRT III complex(GO:0000815)
0.0 1.0 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.5 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 3.3 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.1 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 2.7 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 2.4 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 0.1 GO:0005687 U4 snRNP(GO:0005687)
0.0 0.3 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.4 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.4 GO:0005640 nuclear outer membrane(GO:0005640)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.3 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.4 1.1 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
0.3 1.0 GO:0038100 nodal binding(GO:0038100)
0.3 0.9 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.3 0.9 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.3 0.8 GO:0038131 neuregulin receptor activity(GO:0038131)
0.2 1.2 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.2 0.9 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.2 1.6 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.2 1.8 GO:0004064 arylesterase activity(GO:0004064)
0.2 1.9 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.2 1.6 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.2 1.0 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.2 0.7 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.2 1.7 GO:0004111 creatine kinase activity(GO:0004111)
0.2 1.0 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.2 2.3 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.2 1.7 GO:0070915 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.2 0.6 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.2 1.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 3.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.8 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 1.3 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.4 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.1 2.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.7 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 0.8 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 3.8 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.1 0.8 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.1 3.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.3 GO:0035643 L-DOPA receptor activity(GO:0035643) L-DOPA binding(GO:0072544)
0.1 2.5 GO:0015278 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.1 0.8 GO:0001849 complement component C1q binding(GO:0001849)
0.1 1.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.7 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1 2.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 1.0 GO:0001851 complement component C3b binding(GO:0001851)
0.1 0.3 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.1 13.2 GO:0008565 protein transporter activity(GO:0008565)
0.1 0.3 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.1 0.3 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.1 2.0 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 3.0 GO:0005504 fatty acid binding(GO:0005504)
0.1 3.0 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 2.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 1.6 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 0.5 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 0.3 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.1 1.1 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 2.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 1.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 3.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.2 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.1 0.6 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.8 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 1.6 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 0.9 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.9 GO:0019864 IgG binding(GO:0019864)
0.0 1.7 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.6 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 2.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 2.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.5 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.0 0.5 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.5 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 2.4 GO:0030507 spectrin binding(GO:0030507)
0.0 0.2 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 1.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.3 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.4 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 2.6 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.7 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.3 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 1.1 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 2.0 GO:0030552 cAMP binding(GO:0030552)
0.0 0.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 3.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.2 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.7 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.3 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.0 0.5 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 1.0 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 1.0 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.9 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0 2.0 GO:0030145 manganese ion binding(GO:0030145)
0.0 2.9 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.1 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 2.9 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.7 GO:0004707 MAP kinase activity(GO:0004707)
0.0 2.7 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.7 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.7 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.2 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.7 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.4 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 1.9 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.5 GO:0008494 translation activator activity(GO:0008494)
0.0 0.4 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.5 GO:0070402 NADPH binding(GO:0070402)
0.0 0.8 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.8 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.3 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 1.2 GO:1901476 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.0 0.5 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.4 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.5 GO:0019894 kinesin binding(GO:0019894)
0.0 1.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.2 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 1.0 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.6 GO:0019905 syntaxin binding(GO:0019905)
0.0 1.1 GO:0043022 ribosome binding(GO:0043022)
0.0 1.4 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 0.7 GO:0003774 motor activity(GO:0003774)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 1.3 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 2.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.0 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 2.0 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 3.6 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.8 ST ADRENERGIC Adrenergic Pathway
0.0 4.1 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.0 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.5 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.0 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 1.7 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.8 PID IL1 PATHWAY IL1-mediated signaling events
0.0 4.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.9 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.5 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.9 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.9 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.9 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.7 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.6 PID AP1 PATHWAY AP-1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.5 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 2.2 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.1 2.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 2.0 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 1.7 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.9 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 2.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.2 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 1.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 1.3 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 1.7 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.9 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.7 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 2.2 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.0 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 2.1 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.7 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 1.6 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 1.0 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.7 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 1.1 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.5 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 1.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 1.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 1.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.8 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.8 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 5.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.9 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.3 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 2.5 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway