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Illumina Body Map 2: averaged replicates

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Results for SPDEF

Z-value: 1.74

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Transcription factors associated with SPDEF

Gene Symbol Gene ID Gene Info
ENSG00000124664.6 SPDEF

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SPDEFhg19_v2_chr6_-_34524093_34524135-0.241.9e-01Click!

Activity profile of SPDEF motif

Sorted Z-values of SPDEF motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SPDEF

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr6_-_31560729 4.50 ENST00000340027.5
ENST00000376073.4
ENST00000376072.3
NCR3
natural cytotoxicity triggering receptor 3
chr6_-_41254403 3.73 ENST00000589614.1
ENST00000334475.6
ENST00000591620.1
ENST00000244709.4
TREM1
triggering receptor expressed on myeloid cells 1
chr12_-_123201337 3.68 ENST00000528880.2
HCAR3
hydroxycarboxylic acid receptor 3
chrX_+_123480194 3.68 ENST00000371139.4
SH2D1A
SH2 domain containing 1A
chr14_+_22931924 3.43 ENST00000390477.2
TRDC
T cell receptor delta constant
chr11_+_128563652 3.42 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr12_-_123187890 2.96 ENST00000328880.5
HCAR2
hydroxycarboxylic acid receptor 2
chrX_+_123480375 2.79 ENST00000360027.4
SH2D1A
SH2 domain containing 1A
chr16_+_77225071 2.61 ENST00000439557.2
ENST00000545553.1
MON1B
MON1 secretory trafficking family member B
chr11_-_118122996 2.58 ENST00000525386.1
ENST00000527472.1
ENST00000278949.4
MPZL3
myelin protein zero-like 3
chrX_+_123480421 2.55 ENST00000477673.2
SH2D1A
SH2 domain containing 1A
chr1_+_151129103 2.52 ENST00000368910.3
TNFAIP8L2
tumor necrosis factor, alpha-induced protein 8-like 2
chr8_-_101964738 2.47 ENST00000523938.1
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr15_-_64648273 2.37 ENST00000607537.1
ENST00000303052.7
ENST00000303032.6
CSNK1G1
casein kinase 1, gamma 1
chr11_-_61129723 2.36 ENST00000537680.1
ENST00000426130.2
ENST00000294072.4
CYB561A3
cytochrome b561 family, member A3
chr17_-_7108436 2.30 ENST00000493294.1
DLG4
discs, large homolog 4 (Drosophila)
chr8_-_101964832 2.25 ENST00000523131.1
ENST00000418997.1
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr1_+_84630645 2.25 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chrX_+_117629766 2.23 ENST00000276204.6
ENST00000276202.7
DOCK11
dedicator of cytokinesis 11
chr1_-_19811996 2.17 ENST00000264203.3
ENST00000401084.2
CAPZB
capping protein (actin filament) muscle Z-line, beta
chr1_+_84630053 2.09 ENST00000394838.2
ENST00000370682.3
ENST00000432111.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr1_+_193028717 2.06 ENST00000415442.2
ENST00000506303.1
TROVE2
TROVE domain family, member 2
chr19_+_41082755 2.06 ENST00000291842.5
ENST00000600733.1
SHKBP1
SH3KBP1 binding protein 1
chr1_+_24829384 2.06 ENST00000374395.4
ENST00000436717.2
RCAN3
RCAN family member 3
chr1_+_84629976 2.04 ENST00000446538.1
ENST00000370684.1
ENST00000436133.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr11_-_61129306 2.03 ENST00000544118.1
CYB561A3
cytochrome b561 family, member A3
chr19_+_41082802 2.03 ENST00000600718.1
SHKBP1
SH3KBP1 binding protein 1
chr1_-_21606013 2.00 ENST00000357071.4
ECE1
endothelin converting enzyme 1
chr1_-_19811962 1.99 ENST00000375142.1
ENST00000264202.6
CAPZB
capping protein (actin filament) muscle Z-line, beta
chr11_-_46142948 1.96 ENST00000257821.4
PHF21A
PHD finger protein 21A
chr12_+_29302119 1.92 ENST00000536681.3
FAR2
fatty acyl CoA reductase 2
chr1_+_84630574 1.92 ENST00000413538.1
ENST00000417530.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr11_-_61129335 1.83 ENST00000545361.1
ENST00000539128.1
ENST00000546151.1
ENST00000447532.2
CYB561A3
cytochrome b561 family, member A3
chr8_-_101964265 1.81 ENST00000395958.2
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr11_-_71751715 1.80 ENST00000535947.1
NUMA1
nuclear mitotic apparatus protein 1
chr2_+_101618691 1.77 ENST00000409000.1
ENST00000409028.4
ENST00000409320.3
ENST00000409733.1
ENST00000409650.1
ENST00000409038.1
RPL31
ribosomal protein L31
chr7_+_114562172 1.72 ENST00000393486.1
ENST00000257724.3
MDFIC
MyoD family inhibitor domain containing
chr3_+_32023232 1.71 ENST00000360311.4
ZNF860
zinc finger protein 860
chr2_+_101618965 1.70 ENST00000456292.1
ENST00000409711.1
ENST00000441435.1
RPL31
ribosomal protein L31
chr16_+_77224732 1.67 ENST00000569610.1
ENST00000248248.3
ENST00000567291.1
ENST00000320859.6
ENST00000563612.1
ENST00000563279.1
MON1B
MON1 secretory trafficking family member B
chr15_-_65282232 1.62 ENST00000416889.2
SPG21
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr1_-_184723701 1.61 ENST00000367512.3
EDEM3
ER degradation enhancer, mannosidase alpha-like 3
chr20_-_62199427 1.59 ENST00000427522.2
HELZ2
helicase with zinc finger 2, transcriptional coactivator
chr1_+_84630352 1.58 ENST00000450730.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr19_+_41083064 1.56 ENST00000595631.1
SHKBP1
SH3KBP1 binding protein 1
chr1_+_67395922 1.54 ENST00000401042.3
ENST00000355356.3
MIER1
mesoderm induction early response 1, transcriptional regulator
chr8_-_130951940 1.50 ENST00000522250.1
ENST00000522941.1
ENST00000522746.1
ENST00000520204.1
ENST00000519070.1
ENST00000520254.1
ENST00000519824.2
ENST00000519540.1
FAM49B
family with sequence similarity 49, member B
chr6_-_43484621 1.47 ENST00000506469.1
ENST00000503972.1
YIPF3
Yip1 domain family, member 3
chr15_-_55700522 1.46 ENST00000564092.1
ENST00000310958.6
CCPG1
cell cycle progression 1
chr16_+_70557685 1.45 ENST00000302516.5
ENST00000566095.2
ENST00000577085.1
ENST00000567654.1
SF3B3
splicing factor 3b, subunit 3, 130kDa
chr1_+_84630367 1.44 ENST00000370680.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr8_+_100025476 1.42 ENST00000355155.1
ENST00000357162.2
ENST00000358544.2
ENST00000395996.1
ENST00000441350.2
VPS13B
vacuolar protein sorting 13 homolog B (yeast)
chr12_-_48276710 1.42 ENST00000550314.1
VDR
vitamin D (1,25- dihydroxyvitamin D3) receptor
chr2_+_217363559 1.40 ENST00000600880.1
ENST00000446558.1
RPL37A
ribosomal protein L37a
chr15_-_65282274 1.39 ENST00000204566.2
SPG21
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr17_+_7477040 1.38 ENST00000581384.1
ENST00000577929.1
EIF4A1
eukaryotic translation initiation factor 4A1
chr2_+_162016804 1.38 ENST00000392749.2
ENST00000440506.1
TANK
TRAF family member-associated NFKB activator
chr1_-_153895377 1.37 ENST00000368655.4
GATAD2B
GATA zinc finger domain containing 2B
chr17_-_56082455 1.37 ENST00000578794.1
RP11-159D12.5
Uncharacterized protein
chr2_+_217363826 1.34 ENST00000441179.2
RPL37A
ribosomal protein L37a
chr19_-_1650666 1.34 ENST00000588136.1
TCF3
transcription factor 3
chr15_-_55700457 1.34 ENST00000442196.3
ENST00000563171.1
ENST00000425574.3
CCPG1
cell cycle progression 1
chr4_+_141445333 1.31 ENST00000507667.1
ELMOD2
ELMO/CED-12 domain containing 2
chr12_+_29302023 1.29 ENST00000551451.1
FAR2
fatty acyl CoA reductase 2
chrX_+_49091920 1.27 ENST00000376227.3
CCDC22
coiled-coil domain containing 22
chr6_-_43484718 1.27 ENST00000372422.2
YIPF3
Yip1 domain family, member 3
chr14_-_24615523 1.23 ENST00000559056.1
PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr6_-_150039170 1.23 ENST00000458696.2
ENST00000392273.3
LATS1
large tumor suppressor kinase 1
chr8_-_101965104 1.20 ENST00000437293.1
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr14_-_78083112 1.18 ENST00000216484.2
SPTLC2
serine palmitoyltransferase, long chain base subunit 2
chr8_-_117768023 1.14 ENST00000518949.1
ENST00000522453.1
ENST00000521861.1
ENST00000518995.1
EIF3H
eukaryotic translation initiation factor 3, subunit H
chr19_+_7701985 1.11 ENST00000595950.1
ENST00000441779.2
ENST00000221283.5
ENST00000414284.2
STXBP2
syntaxin binding protein 2
chr2_+_162016916 1.11 ENST00000405852.1
TANK
TRAF family member-associated NFKB activator
chr2_-_39103014 1.10 ENST00000295373.6
ENST00000417233.1
DHX57
DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
chr15_-_80215984 1.10 ENST00000485386.1
ENST00000479961.1
ST20
ST20-MTHFS
suppressor of tumorigenicity 20
ST20-MTHFS readthrough
chr14_+_60716159 1.10 ENST00000325658.3
PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr5_-_114961673 1.09 ENST00000333314.3
TMED7-TICAM2
TMED7-TICAM2 readthrough
chr11_+_61129456 1.08 ENST00000278826.6
TMEM138
transmembrane protein 138
chr2_+_65454926 1.08 ENST00000542850.1
ENST00000377982.4
ACTR2
ARP2 actin-related protein 2 homolog (yeast)
chr2_+_162016827 1.08 ENST00000429217.1
ENST00000406287.1
ENST00000402568.1
TANK
TRAF family member-associated NFKB activator
chr15_+_41186609 1.08 ENST00000220509.5
VPS18
vacuolar protein sorting 18 homolog (S. cerevisiae)
chr19_+_58898627 1.07 ENST00000598098.1
ENST00000598495.1
ENST00000196551.3
ENST00000596046.1
RPS5
ribosomal protein S5
chrX_-_153775760 1.07 ENST00000440967.1
ENST00000393564.2
ENST00000369620.2
G6PD
glucose-6-phosphate dehydrogenase
chr16_-_28503357 1.06 ENST00000333496.9
ENST00000561505.1
ENST00000567963.1
ENST00000354630.5
ENST00000355477.5
ENST00000357076.5
ENST00000565688.1
ENST00000359984.7
CLN3
ceroid-lipofuscinosis, neuronal 3
chr8_-_56987057 1.05 ENST00000518875.1
RPS20
ribosomal protein S20
chr7_-_77427676 1.05 ENST00000257663.3
TMEM60
transmembrane protein 60
chr15_-_55700216 1.05 ENST00000569205.1
CCPG1
cell cycle progression 1
chr14_-_64010006 1.05 ENST00000555899.1
PPP2R5E
protein phosphatase 2, regulatory subunit B', epsilon isoform
chr16_-_28503080 1.04 ENST00000565316.1
ENST00000565778.1
ENST00000357857.9
ENST00000568558.1
ENST00000357806.7
CLN3
ceroid-lipofuscinosis, neuronal 3
chr1_+_193028552 1.03 ENST00000400968.2
ENST00000432079.1
TROVE2
TROVE domain family, member 2
chr11_-_71752100 1.01 ENST00000542977.1
NUMA1
nuclear mitotic apparatus protein 1
chr7_+_99746514 1.01 ENST00000341942.5
ENST00000441173.1
LAMTOR4
late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
chr17_-_8286484 1.00 ENST00000582556.1
ENST00000584164.1
ENST00000293842.5
ENST00000584343.1
ENST00000578812.1
ENST00000583011.1
RPL26
ribosomal protein L26
chr12_+_50135588 1.00 ENST00000423828.1
ENST00000550445.1
TMBIM6
transmembrane BAX inhibitor motif containing 6
chr7_+_114562616 1.00 ENST00000448022.1
MDFIC
MyoD family inhibitor domain containing
chr1_-_193028426 0.99 ENST00000367450.3
ENST00000530098.2
ENST00000367451.4
ENST00000367448.1
ENST00000367449.1
UCHL5
ubiquitin carboxyl-terminal hydrolase L5
chr19_+_19496624 0.99 ENST00000494516.2
ENST00000360315.3
ENST00000252577.5
GATAD2A
GATA zinc finger domain containing 2A
chr8_-_101965146 0.99 ENST00000395957.2
ENST00000395948.2
ENST00000457309.1
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr1_-_184723942 0.98 ENST00000318130.8
EDEM3
ER degradation enhancer, mannosidase alpha-like 3
chr2_+_65454863 0.97 ENST00000260641.5
ACTR2
ARP2 actin-related protein 2 homolog (yeast)
chrX_-_135962876 0.97 ENST00000431446.3
ENST00000570135.1
ENST00000320676.7
ENST00000562646.1
RBMX
RNA binding motif protein, X-linked
chr15_+_41186637 0.97 ENST00000558474.1
VPS18
vacuolar protein sorting 18 homolog (S. cerevisiae)
chrX_-_135962923 0.97 ENST00000565438.1
RBMX
RNA binding motif protein, X-linked
chr19_+_37178482 0.96 ENST00000536254.2
ZNF567
zinc finger protein 567
chr8_+_22462532 0.96 ENST00000389279.3
CCAR2
cell cycle and apoptosis regulator 2
chr16_+_25123148 0.95 ENST00000570981.1
LCMT1
leucine carboxyl methyltransferase 1
chr4_-_83812157 0.93 ENST00000513323.1
SEC31A
SEC31 homolog A (S. cerevisiae)
chr14_-_24711764 0.92 ENST00000557921.1
ENST00000558476.1
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr12_-_102513843 0.92 ENST00000551744.2
ENST00000552283.1
NUP37
nucleoporin 37kDa
chr14_-_75593708 0.91 ENST00000557673.1
ENST00000238616.5
NEK9
NIMA-related kinase 9
chr19_-_1174226 0.91 ENST00000587024.1
ENST00000361757.3
SBNO2
strawberry notch homolog 2 (Drosophila)
chr14_+_75348600 0.91 ENST00000334212.6
ENST00000554806.1
DLST
dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
chr17_-_47755338 0.90 ENST00000508805.1
ENST00000515508.2
ENST00000451526.2
ENST00000507970.1
SPOP
speckle-type POZ protein
chrX_-_153775426 0.90 ENST00000393562.2
G6PD
glucose-6-phosphate dehydrogenase
chrX_+_47444613 0.90 ENST00000445623.1
TIMP1
TIMP metallopeptidase inhibitor 1
chr7_+_77428066 0.89 ENST00000422959.2
ENST00000307305.8
ENST00000424760.1
PHTF2
putative homeodomain transcription factor 2
chr2_-_68479614 0.89 ENST00000234310.3
PPP3R1
protein phosphatase 3, regulatory subunit B, alpha
chr1_-_193028621 0.87 ENST00000367455.4
ENST00000367454.1
UCHL5
ubiquitin carboxyl-terminal hydrolase L5
chr1_-_193028632 0.87 ENST00000421683.1
UCHL5
ubiquitin carboxyl-terminal hydrolase L5
chr6_-_150039249 0.86 ENST00000543571.1
LATS1
large tumor suppressor kinase 1
chr8_-_56987061 0.86 ENST00000009589.3
ENST00000524349.1
ENST00000519606.1
ENST00000519807.1
ENST00000521262.1
ENST00000520627.1
RPS20
ribosomal protein S20
chr19_-_37178284 0.85 ENST00000425254.2
ENST00000590952.1
ENST00000433232.1
AC074138.3
AC074138.3
chr3_+_196669494 0.85 ENST00000602845.1
NCBP2-AS2
NCBP2 antisense RNA 2 (head to head)
chr17_-_18218237 0.85 ENST00000542570.1
TOP3A
topoisomerase (DNA) III alpha
chr19_-_41220540 0.83 ENST00000594490.1
ADCK4
aarF domain containing kinase 4
chr18_+_21032781 0.83 ENST00000339486.3
RIOK3
RIO kinase 3
chr22_-_22337154 0.83 ENST00000413067.2
ENST00000437929.1
ENST00000456075.1
ENST00000434517.1
ENST00000424393.1
ENST00000449704.1
ENST00000437103.1
TOP3B
topoisomerase (DNA) III beta
chr14_-_24711470 0.83 ENST00000559969.1
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr5_+_110074685 0.83 ENST00000355943.3
ENST00000447245.2
SLC25A46
solute carrier family 25, member 46
chr1_+_39456895 0.82 ENST00000432648.3
ENST00000446189.2
ENST00000372984.4
AKIRIN1
akirin 1
chr10_-_120840309 0.82 ENST00000369144.3
EIF3A
eukaryotic translation initiation factor 3, subunit A
chr6_-_42713792 0.81 ENST00000372876.1
TBCC
tubulin folding cofactor C
chr7_-_38948774 0.81 ENST00000395969.2
ENST00000414632.1
ENST00000310301.4
VPS41
vacuolar protein sorting 41 homolog (S. cerevisiae)
chr17_-_47865948 0.81 ENST00000513602.1
FAM117A
family with sequence similarity 117, member A
chr4_+_141445311 0.79 ENST00000323570.3
ENST00000511887.2
ELMOD2
ELMO/CED-12 domain containing 2
chr14_-_24615805 0.79 ENST00000560410.1
PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr17_-_18218270 0.79 ENST00000321105.5
TOP3A
topoisomerase (DNA) III alpha
chr13_+_25670268 0.78 ENST00000281589.3
PABPC3
poly(A) binding protein, cytoplasmic 3
chr14_+_60715928 0.78 ENST00000395076.4
PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr12_+_27396901 0.78 ENST00000541191.1
ENST00000389032.3
STK38L
serine/threonine kinase 38 like
chr19_-_4723761 0.78 ENST00000597849.1
ENST00000598800.1
ENST00000602161.1
ENST00000597726.1
ENST00000601130.1
ENST00000262960.9
DPP9
dipeptidyl-peptidase 9
chr4_+_153701081 0.77 ENST00000451320.2
ENST00000429148.2
ENST00000353617.2
ENST00000405727.2
ENST00000356064.3
ARFIP1
ADP-ribosylation factor interacting protein 1
chr5_+_86564739 0.77 ENST00000456692.2
ENST00000512763.1
ENST00000506290.1
RASA1
RAS p21 protein activator (GTPase activating protein) 1
chr8_-_56986768 0.76 ENST00000523936.1
RPS20
ribosomal protein S20
chr14_-_21737551 0.76 ENST00000554891.1
ENST00000555883.1
ENST00000553753.1
ENST00000555914.1
ENST00000557336.1
ENST00000555215.1
ENST00000556628.1
ENST00000555137.1
ENST00000556226.1
ENST00000555309.1
ENST00000556142.1
ENST00000554969.1
ENST00000554455.1
ENST00000556513.1
ENST00000557201.1
ENST00000420743.2
ENST00000557768.1
ENST00000553300.1
ENST00000554383.1
ENST00000554539.1
HNRNPC
heterogeneous nuclear ribonucleoprotein C (C1/C2)
chr14_-_24711806 0.76 ENST00000540705.1
ENST00000538777.1
ENST00000558566.1
ENST00000559019.1
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr14_-_31926623 0.76 ENST00000356180.4
DTD2
D-tyrosyl-tRNA deacylase 2 (putative)
chr1_+_22351977 0.76 ENST00000420503.1
ENST00000416769.1
ENST00000404210.2
LINC00339
long intergenic non-protein coding RNA 339
chr18_+_48556470 0.75 ENST00000589076.1
ENST00000590061.1
ENST00000591914.1
ENST00000342988.3
SMAD4
SMAD family member 4
chr22_+_22020353 0.75 ENST00000456792.2
PPIL2
peptidylprolyl isomerase (cyclophilin)-like 2
chr20_+_60962143 0.75 ENST00000343986.4
RPS21
ribosomal protein S21
chr14_-_24711865 0.75 ENST00000399423.4
ENST00000267415.7
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr17_-_47755436 0.74 ENST00000505581.1
ENST00000514121.1
ENST00000393328.2
ENST00000509079.1
ENST00000393331.3
ENST00000347630.2
ENST00000504102.1
SPOP
speckle-type POZ protein
chr22_+_44351419 0.73 ENST00000396202.3
SAMM50
SAMM50 sorting and assembly machinery component
chr1_+_235492300 0.73 ENST00000476121.1
ENST00000497327.1
GGPS1
geranylgeranyl diphosphate synthase 1
chr19_-_52674696 0.72 ENST00000597252.1
ZNF836
zinc finger protein 836
chr16_-_28503327 0.72 ENST00000535392.1
ENST00000395653.4
CLN3
ceroid-lipofuscinosis, neuronal 3
chr11_+_73498973 0.72 ENST00000537007.1
MRPL48
mitochondrial ribosomal protein L48
chr8_+_8860314 0.72 ENST00000250263.7
ENST00000519292.1
ERI1
exoribonuclease 1
chr2_+_48667983 0.72 ENST00000449090.2
PPP1R21
protein phosphatase 1, regulatory subunit 21
chr1_+_203765437 0.71 ENST00000550078.1
ZBED6
zinc finger, BED-type containing 6
chr22_-_22337204 0.71 ENST00000430142.1
ENST00000357179.5
TOP3B
topoisomerase (DNA) III beta
chr3_-_69101413 0.71 ENST00000398559.2
TMF1
TATA element modulatory factor 1
chr7_-_6098770 0.71 ENST00000536084.1
ENST00000446699.1
ENST00000199389.6
EIF2AK1
eukaryotic translation initiation factor 2-alpha kinase 1
chr2_-_27294500 0.70 ENST00000447619.1
ENST00000429985.1
ENST00000456793.1
OST4
oligosaccharyltransferase 4 homolog (S. cerevisiae)
chr11_+_111957497 0.70 ENST00000375549.3
ENST00000528182.1
ENST00000528048.1
ENST00000528021.1
ENST00000526592.1
ENST00000525291.1
SDHD
succinate dehydrogenase complex, subunit D, integral membrane protein
chr11_+_61129827 0.70 ENST00000542946.1
TMEM138
transmembrane protein 138
chr17_-_35969409 0.69 ENST00000394378.2
ENST00000585472.1
ENST00000591288.1
ENST00000502449.2
ENST00000345615.4
ENST00000346661.4
ENST00000585689.1
ENST00000339208.6
SYNRG
synergin, gamma
chrX_+_47053208 0.68 ENST00000442035.1
ENST00000457753.1
ENST00000335972.6
UBA1
ubiquitin-like modifier activating enzyme 1
chr1_+_43124087 0.68 ENST00000304979.3
ENST00000372550.1
ENST00000440068.1
PPIH
peptidylprolyl isomerase H (cyclophilin H)
chr5_+_31532373 0.68 ENST00000325366.9
ENST00000355907.3
ENST00000507818.2
C5orf22
chromosome 5 open reading frame 22
chr1_+_110091189 0.68 ENST00000369851.4
GNAI3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr3_-_139108463 0.68 ENST00000512242.1
COPB2
coatomer protein complex, subunit beta 2 (beta prime)
chr7_+_77428149 0.66 ENST00000415251.2
ENST00000275575.7
PHTF2
putative homeodomain transcription factor 2
chr11_+_57435441 0.66 ENST00000528177.1
ZDHHC5
zinc finger, DHHC-type containing 5
chr14_-_21737610 0.66 ENST00000320084.7
ENST00000449098.1
ENST00000336053.6
HNRNPC
heterogeneous nuclear ribonucleoprotein C (C1/C2)
chr14_-_64010046 0.66 ENST00000337537.3
PPP2R5E
protein phosphatase 2, regulatory subunit B', epsilon isoform
chr8_+_22462145 0.65 ENST00000308511.4
ENST00000523801.1
ENST00000521301.1
CCAR2
cell cycle and apoptosis regulator 2
chr17_+_18218587 0.64 ENST00000406438.3
SMCR8
Smith-Magenis syndrome chromosome region, candidate 8
chr2_+_217363793 0.64 ENST00000456586.1
ENST00000598925.1
ENST00000427280.2
RPL37A
ribosomal protein L37a
chr7_+_100273736 0.64 ENST00000412215.1
ENST00000393924.1
GNB2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr19_+_19496728 0.63 ENST00000537887.1
ENST00000417582.2
GATAD2A
GATA zinc finger domain containing 2A
chr1_-_28415075 0.63 ENST00000373863.3
ENST00000436342.2
ENST00000540618.1
ENST00000545175.1
EYA3
eyes absent homolog 3 (Drosophila)
chr20_+_49126881 0.63 ENST00000371621.3
ENST00000541713.1
PTPN1
protein tyrosine phosphatase, non-receptor type 1
chr3_-_69101461 0.63 ENST00000543976.1
TMF1
TATA element modulatory factor 1
chr12_+_50794891 0.62 ENST00000517559.1
LARP4
La ribonucleoprotein domain family, member 4
chr22_+_22020273 0.61 ENST00000412327.1
ENST00000335025.8
ENST00000398831.3
ENST00000492445.2
ENST00000458567.1
ENST00000406385.1
PPIL2
peptidylprolyl isomerase (cyclophilin)-like 2
chr3_-_196669298 0.60 ENST00000411704.1
ENST00000452404.2
NCBP2
nuclear cap binding protein subunit 2, 20kDa
chr15_-_43663214 0.60 ENST00000561661.1
ZSCAN29
zinc finger and SCAN domain containing 29
chr14_+_75348592 0.60 ENST00000334220.4
DLST
dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
chr4_-_83812402 0.58 ENST00000395310.2
SEC31A
SEC31 homolog A (S. cerevisiae)
chr10_-_14996017 0.58 ENST00000378241.1
ENST00000456122.1
ENST00000418843.1
ENST00000378249.1
ENST00000396817.2
ENST00000378255.1
ENST00000378254.1
ENST00000378278.2
ENST00000357717.2
DCLRE1C
DNA cross-link repair 1C
chrX_-_122866874 0.58 ENST00000245838.8
ENST00000355725.4
THOC2
THO complex 2
chr18_+_21033239 0.57 ENST00000581585.1
ENST00000577501.1
RIOK3
RIO kinase 3
chr21_-_46221684 0.57 ENST00000330942.5
UBE2G2
ubiquitin-conjugating enzyme E2G 2
chr7_+_93551011 0.57 ENST00000248564.5
GNG11
guanine nucleotide binding protein (G protein), gamma 11
chr9_-_34126730 0.57 ENST00000361264.4
DCAF12
DDB1 and CUL4 associated factor 12
chr4_-_83812248 0.57 ENST00000514326.1
ENST00000505434.1
ENST00000503058.1
ENST00000348405.4
ENST00000505984.1
ENST00000513858.1
ENST00000508479.1
ENST00000443462.2
ENST00000508502.1
ENST00000509142.1
ENST00000432794.1
ENST00000448323.1
ENST00000326950.5
ENST00000311785.7
SEC31A
SEC31 homolog A (S. cerevisiae)
chrX_+_153775869 0.56 ENST00000424839.1
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr12_-_49961883 0.56 ENST00000553173.1
ENST00000550165.1
ENST00000546244.1
ENST00000343810.4
MCRS1
microspherule protein 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.5 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
1.4 4.3 GO:0019085 early viral transcription(GO:0019085)
1.1 11.3 GO:0097338 response to clozapine(GO:0097338)
0.7 2.8 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.7 4.2 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.6 3.9 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.6 3.7 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.5 3.0 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.5 8.7 GO:0090168 Golgi reassembly(GO:0090168)
0.4 3.6 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.4 2.1 GO:0001827 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.4 3.3 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.4 3.2 GO:0010166 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.4 1.2 GO:0006667 sphinganine metabolic process(GO:0006667)
0.4 1.1 GO:0033385 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.4 1.5 GO:0046833 snRNA export from nucleus(GO:0006408) positive regulation of RNA export from nucleus(GO:0046833)
0.4 1.4 GO:0010980 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980) apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.3 0.3 GO:1900244 positive regulation of synaptic vesicle endocytosis(GO:1900244) positive regulation of synaptic vesicle recycling(GO:1903423)
0.3 2.0 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.3 1.0 GO:0006481 C-terminal protein methylation(GO:0006481)
0.3 2.0 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.3 2.6 GO:0097466 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.3 1.3 GO:0016334 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.3 9.0 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.3 2.1 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.3 1.4 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.3 2.8 GO:0032887 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.3 0.8 GO:0002188 translation reinitiation(GO:0002188)
0.3 2.2 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.3 1.3 GO:2000843 testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
0.3 0.8 GO:0003220 left ventricular cardiac muscle tissue morphogenesis(GO:0003220) cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250)
0.3 1.5 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.2 0.9 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.2 0.7 GO:1904585 response to putrescine(GO:1904585) cellular response to putrescine(GO:1904586) hepatocyte dedifferentiation(GO:1990828)
0.2 1.5 GO:2000568 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.2 1.0 GO:1901545 cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.2 0.6 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.2 0.8 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.2 0.8 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.2 1.4 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.2 2.3 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.2 0.4 GO:1902568 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.2 1.3 GO:1904721 negative regulation of mRNA cleavage(GO:0031438) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.2 2.0 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.2 1.3 GO:0002326 B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152)
0.2 1.2 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.2 3.7 GO:0006265 DNA topological change(GO:0006265)
0.2 1.0 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.1 0.6 GO:0035669 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.1 0.1 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.1 0.7 GO:0006447 regulation of translational initiation by iron(GO:0006447)
0.1 0.6 GO:1990502 dense core granule maturation(GO:1990502)
0.1 0.4 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.1 2.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 1.5 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.1 1.6 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1 1.2 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.1 2.7 GO:0048853 forebrain morphogenesis(GO:0048853)
0.1 0.5 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 0.6 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.1 0.4 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 3.2 GO:0035855 megakaryocyte development(GO:0035855)
0.1 0.8 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.1 1.0 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1 0.9 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 1.5 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.1 0.8 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 2.0 GO:0006450 regulation of translational fidelity(GO:0006450)
0.1 1.3 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1 5.7 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742)
0.1 0.5 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 9.1 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 0.6 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 1.9 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 0.8 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.1 0.6 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.1 1.1 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.1 1.4 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.1 0.5 GO:0006021 inositol biosynthetic process(GO:0006021)
0.1 2.7 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.1 0.8 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.9 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.1 GO:0006043 glucosamine catabolic process(GO:0006043)
0.0 3.0 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.4 GO:0010624 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.7 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 3.4 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 1.2 GO:0043101 purine-containing compound salvage(GO:0043101)
0.0 0.2 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.1 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.0 0.4 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.6 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.4 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.6 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 2.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.6 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 2.6 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.8 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0 0.6 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 0.4 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 1.3 GO:0033006 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.0 0.2 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 1.0 GO:0018345 protein palmitoylation(GO:0018345)
0.0 1.8 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.2 GO:1901620 regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901620)
0.0 0.5 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.3 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 1.0 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.5 GO:0007172 signal complex assembly(GO:0007172)
0.0 1.9 GO:0007077 mitotic nuclear envelope disassembly(GO:0007077)
0.0 0.2 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0 1.0 GO:0043276 anoikis(GO:0043276)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 2.0 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0 2.1 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.0 1.2 GO:1901998 toxin transport(GO:1901998)
0.0 1.2 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.2 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 2.5 GO:0050868 negative regulation of T cell activation(GO:0050868)
0.0 0.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.4 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 1.4 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 2.6 GO:0042303 molting cycle(GO:0042303) hair cycle(GO:0042633)
0.0 0.2 GO:0000338 protein deneddylation(GO:0000338)
0.0 1.3 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.7 GO:1903146 regulation of mitophagy(GO:1903146)
0.0 1.9 GO:0016575 histone deacetylation(GO:0016575)
0.0 1.8 GO:0050688 regulation of defense response to virus(GO:0050688)
0.0 1.5 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.2 GO:0045116 protein neddylation(GO:0045116)
0.0 0.7 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 1.1 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.2 GO:0097354 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0 3.1 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.4 GO:0003091 renal water homeostasis(GO:0003091)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.3 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.5 1.6 GO:0044609 DBIRD complex(GO:0044609)
0.5 4.2 GO:0071203 WASH complex(GO:0071203)
0.4 11.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.3 2.0 GO:0008537 proteasome activator complex(GO:0008537)
0.3 2.0 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.3 1.9 GO:0044530 supraspliceosomal complex(GO:0044530)
0.3 2.9 GO:0033263 CORVET complex(GO:0033263)
0.3 2.8 GO:0055028 cortical microtubule(GO:0055028)
0.3 0.8 GO:1903095 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.3 1.3 GO:0042643 actomyosin, actin portion(GO:0042643)
0.2 1.5 GO:0005846 nuclear cap binding complex(GO:0005846)
0.2 0.7 GO:0034455 t-UTP complex(GO:0034455)
0.2 0.6 GO:0043614 multi-eIF complex(GO:0043614)
0.2 0.7 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.2 0.7 GO:0071001 U4/U6 snRNP(GO:0071001)
0.2 1.2 GO:1902560 GMP reductase complex(GO:1902560)
0.2 2.3 GO:0098839 postsynaptic density membrane(GO:0098839)
0.1 2.1 GO:0030478 actin cap(GO:0030478)
0.1 1.5 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 1.1 GO:0044194 cytolytic granule(GO:0044194)
0.1 2.7 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.1 1.4 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.5 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 0.8 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.1 1.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.8 GO:0032444 activin responsive factor complex(GO:0032444)
0.1 0.7 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 1.2 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 0.9 GO:0005955 calcineurin complex(GO:0005955)
0.1 1.2 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.1 1.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.4 GO:0097441 basilar dendrite(GO:0097441)
0.1 1.0 GO:0071986 Ragulator complex(GO:0071986)
0.1 1.0 GO:0000322 storage vacuole(GO:0000322)
0.1 5.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 0.7 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.1 7.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 3.4 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.6 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 1.1 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 1.4 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 1.9 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 0.9 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 1.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 2.2 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.6 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.8 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 1.4 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.6 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.3 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.5 GO:0042588 zymogen granule(GO:0042588)
0.0 1.0 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 1.6 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.7 GO:0030008 TRAPP complex(GO:0030008)
0.0 1.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 2.0 GO:1990391 DNA repair complex(GO:1990391)
0.0 6.1 GO:0031902 late endosome membrane(GO:0031902)
0.0 1.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 7.7 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 1.1 GO:0097346 INO80-type complex(GO:0097346)
0.0 0.8 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.7 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.5 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.4 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.5 GO:0010369 chromocenter(GO:0010369)
0.0 1.5 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 2.7 GO:0005776 autophagosome(GO:0005776)
0.0 0.7 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.2 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.0 1.5 GO:0005774 vacuolar membrane(GO:0005774)
0.0 2.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 2.4 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.8 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 3.0 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 1.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.6 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 2.1 GO:0016605 PML body(GO:0016605)
0.0 0.5 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.0 GO:0035577 azurophil granule membrane(GO:0035577)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.5 3.2 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.5 1.4 GO:1902271 D3 vitamins binding(GO:1902271)
0.5 11.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.4 3.6 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.4 2.0 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.4 3.7 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.4 1.1 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.3 1.3 GO:0070644 vitamin D response element binding(GO:0070644)
0.3 1.0 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.3 1.5 GO:0016748 succinyltransferase activity(GO:0016748)
0.3 0.9 GO:0051500 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.3 2.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.3 3.1 GO:0030620 U2 snRNA binding(GO:0030620)
0.2 0.7 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.2 0.7 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.2 1.1 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.2 2.0 GO:0061133 endopeptidase activator activity(GO:0061133)
0.2 1.5 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.2 1.0 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.2 0.6 GO:0004560 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.2 2.6 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.2 3.0 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.2 1.2 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.2 0.5 GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity(GO:0008441)
0.2 1.3 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.1 1.2 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 1.5 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 3.0 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 0.8 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1 2.4 GO:0030957 Tat protein binding(GO:0030957)
0.1 0.4 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 0.7 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 0.5 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 3.0 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 1.4 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 1.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 1.4 GO:0089720 caspase binding(GO:0089720)
0.1 0.7 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 2.7 GO:0070628 proteasome binding(GO:0070628)
0.1 0.4 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 0.8 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 0.6 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.7 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.5 GO:1990405 protein antigen binding(GO:1990405)
0.1 0.8 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 0.7 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 1.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.4 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.1 3.9 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 1.3 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.8 GO:0043199 sulfate binding(GO:0043199)
0.1 3.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 1.4 GO:0000339 RNA cap binding(GO:0000339)
0.0 7.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 12.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.1 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 0.8 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.7 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.4 GO:0008097 5S rRNA binding(GO:0008097)
0.0 1.6 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.4 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 1.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 4.2 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 1.0 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.2 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.0 1.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 8.7 GO:0044325 ion channel binding(GO:0044325)
0.0 2.1 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 3.4 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.7 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 2.0 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.9 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.4 GO:0008494 translation activator activity(GO:0008494)
0.0 2.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.3 GO:0051787 misfolded protein binding(GO:0051787)
0.0 1.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 3.7 GO:0030674 protein binding, bridging(GO:0030674)
0.0 1.2 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.5 GO:0017166 vinculin binding(GO:0017166)
0.0 0.8 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 5.7 GO:0051015 actin filament binding(GO:0051015)
0.0 1.5 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.6 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.2 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.0 2.2 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 1.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.2 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.2 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.3 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.5 GO:0003682 chromatin binding(GO:0003682)
0.0 0.2 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 1.7 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 1.0 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.5 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.7 GO:0043621 protein self-association(GO:0043621)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 20.0 PID IL3 PATHWAY IL3-mediated signaling events
0.1 3.1 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 2.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 2.5 PID ATM PATHWAY ATM pathway
0.0 2.3 ST GA12 PATHWAY G alpha 12 Pathway
0.0 11.2 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 2.1 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 4.7 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.0 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 1.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 3.0 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 2.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.8 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 2.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.7 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.9 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.9 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 2.7 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.6 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.6 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 1.3 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 20.0 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 2.6 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 2.8 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 3.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 1.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 1.4 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 6.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 9.7 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.1 3.1 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 0.8 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 2.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 2.2 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 3.6 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.1 1.0 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 3.3 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 1.7 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 1.9 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.1 2.1 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.7 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.7 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 1.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.0 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.9 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.7 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 1.1 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.6 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 5.1 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 1.6 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 6.6 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 2.1 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.9 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.8 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 1.2 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.8 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.8 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.9 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.1 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins