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Illumina Body Map 2: averaged replicates

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Results for SPIC

Z-value: 4.54

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Transcription factors associated with SPIC

Gene Symbol Gene ID Gene Info
ENSG00000166211.6 SPIC

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SPIChg19_v2_chr12_+_101869096_1018691990.154.0e-01Click!

Activity profile of SPIC motif

Sorted Z-values of SPIC motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SPIC

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr17_-_72709050 12.99 ENST00000583937.1
ENST00000301573.9
ENST00000326165.6
ENST00000469092.1
CD300LF
CD300 molecule-like family member f
chr12_+_54892550 11.24 ENST00000545638.2
NCKAP1L
NCK-associated protein 1-like
chr4_-_74853897 11.21 ENST00000296028.3
PPBP
pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
chr19_+_42381337 10.71 ENST00000597454.1
ENST00000444740.2
CD79A
CD79a molecule, immunoglobulin-associated alpha
chr1_+_159772121 10.46 ENST00000339348.5
ENST00000392235.3
ENST00000368106.3
FCRL6
Fc receptor-like 6
chr19_-_8642289 10.46 ENST00000596675.1
ENST00000338257.8
MYO1F
myosin IF
chr6_+_31554826 10.00 ENST00000376089.2
ENST00000396112.2
LST1
leukocyte specific transcript 1
chr20_+_48892848 9.89 ENST00000422459.1
RP11-290F20.3
RP11-290F20.3
chr1_-_157789850 9.59 ENST00000491942.1
ENST00000358292.3
ENST00000368176.3
FCRL1
Fc receptor-like 1
chr14_+_88471468 9.48 ENST00000267549.3
GPR65
G protein-coupled receptor 65
chr1_-_160681593 9.06 ENST00000368045.3
ENST00000368046.3
CD48
CD48 molecule
chr1_+_161677034 9.02 ENST00000349527.4
ENST00000309691.6
ENST00000294796.4
ENST00000367953.3
ENST00000367950.1
FCRLA
Fc receptor-like A
chrX_+_78200829 8.98 ENST00000544091.1
P2RY10
purinergic receptor P2Y, G-protein coupled, 10
chrX_+_78200913 8.90 ENST00000171757.2
P2RY10
purinergic receptor P2Y, G-protein coupled, 10
chr1_+_192127578 8.86 ENST00000367460.3
RGS18
regulator of G-protein signaling 18
chr19_-_10446449 8.56 ENST00000592439.1
ICAM3
intercellular adhesion molecule 3
chr16_+_30194916 8.39 ENST00000570045.1
ENST00000565497.1
ENST00000570244.1
CORO1A
coronin, actin binding protein, 1A
chr7_-_142099977 8.30 ENST00000390359.3
TRBV7-8
T cell receptor beta variable 7-8
chr6_-_159466136 8.29 ENST00000367066.3
ENST00000326965.6
TAGAP
T-cell activation RhoGTPase activating protein
chr16_+_30485267 8.24 ENST00000569725.1
ITGAL
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chrX_-_47489244 8.21 ENST00000469388.1
ENST00000396992.3
ENST00000377005.2
CFP
complement factor properdin
chr1_+_161676983 8.20 ENST00000367957.2
FCRLA
Fc receptor-like A
chr22_+_37309662 8.11 ENST00000403662.3
ENST00000262825.5
CSF2RB
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr14_-_23284703 7.97 ENST00000555911.1
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr12_-_9885888 7.97 ENST00000327839.3
CLECL1
C-type lectin-like 1
chr11_-_58980342 7.68 ENST00000361050.3
MPEG1
macrophage expressed 1
chr6_-_133079022 7.66 ENST00000525289.1
ENST00000326499.6
VNN2
vanin 2
chr6_-_159466042 7.34 ENST00000338313.5
TAGAP
T-cell activation RhoGTPase activating protein
chr1_-_25256368 7.34 ENST00000308873.6
RUNX3
runt-related transcription factor 3
chr1_-_157746909 7.34 ENST00000392274.3
ENST00000361516.3
ENST00000368181.4
FCRL2
Fc receptor-like 2
chr14_-_23284675 7.31 ENST00000555959.1
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr15_-_90358048 7.29 ENST00000300060.6
ENST00000560137.1
ANPEP
alanyl (membrane) aminopeptidase
chr19_-_54784937 7.20 ENST00000434421.1
ENST00000314446.5
ENST00000391749.4
LILRB2
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
chr19_-_39108568 7.19 ENST00000586296.1
MAP4K1
mitogen-activated protein kinase kinase kinase kinase 1
chr17_-_72619869 7.16 ENST00000392619.1
ENST00000426295.2
CD300E
CD300e molecule
chr6_+_31554612 7.10 ENST00000211921.7
LST1
leukocyte specific transcript 1
chr17_-_72619783 7.03 ENST00000328630.3
CD300E
CD300e molecule
chr17_+_72462525 7.00 ENST00000360141.3
CD300A
CD300a molecule
chr5_-_66492562 6.94 ENST00000256447.4
CD180
CD180 molecule
chr19_-_51875894 6.85 ENST00000600427.1
ENST00000595217.1
ENST00000221978.5
NKG7
natural killer cell group 7 sequence
chr6_+_106534192 6.82 ENST00000369091.2
ENST00000369096.4
PRDM1
PR domain containing 1, with ZNF domain
chr19_+_49838653 6.75 ENST00000598095.1
ENST00000426897.2
ENST00000323906.4
ENST00000535669.2
ENST00000597602.1
ENST00000595660.1
CD37
CD37 molecule
chr17_-_72527605 6.72 ENST00000392621.1
ENST00000314401.3
CD300LB
CD300 molecule-like family member b
chr2_+_182321925 6.67 ENST00000339307.4
ENST00000397033.2
ITGA4
integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
chr19_+_55084438 6.66 ENST00000439534.1
LILRA2
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
chr11_-_118083600 6.52 ENST00000524477.1
AMICA1
adhesion molecule, interacts with CXADR antigen 1
chr9_+_214842 6.50 ENST00000453981.1
ENST00000432829.2
DOCK8
dedicator of cytokinesis 8
chr20_-_1638408 6.49 ENST00000303415.3
ENST00000381583.2
SIRPG
signal-regulatory protein gamma
chr1_+_161676739 6.42 ENST00000236938.6
ENST00000367959.2
ENST00000546024.1
ENST00000540521.1
ENST00000367949.2
ENST00000350710.3
ENST00000540926.1
FCRLA
Fc receptor-like A
chr2_+_89998789 6.40 ENST00000453166.2
IGKV2D-28
immunoglobulin kappa variable 2D-28
chr9_+_215158 6.38 ENST00000479404.1
DOCK8
dedicator of cytokinesis 8
chrX_-_70838306 6.37 ENST00000373691.4
ENST00000373693.3
CXCR3
chemokine (C-X-C motif) receptor 3
chr6_+_31554779 6.36 ENST00000376090.2
LST1
leukocyte specific transcript 1
chr19_-_39108643 6.33 ENST00000396857.2
MAP4K1
mitogen-activated protein kinase kinase kinase kinase 1
chr8_+_11351494 6.31 ENST00000259089.4
BLK
B lymphoid tyrosine kinase
chr7_+_150382781 6.27 ENST00000223293.5
ENST00000474605.1
GIMAP2
GTPase, IMAP family member 2
chr22_+_23247030 6.20 ENST00000390324.2
IGLJ3
immunoglobulin lambda joining 3
chr12_-_9885702 6.14 ENST00000542530.1
CLECL1
C-type lectin-like 1
chr10_-_98480243 6.13 ENST00000339364.5
PIK3AP1
phosphoinositide-3-kinase adaptor protein 1
chr13_-_46756351 6.11 ENST00000323076.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr2_+_89999259 6.11 ENST00000558026.1
IGKV2D-28
immunoglobulin kappa variable 2D-28
chr20_-_1638360 6.09 ENST00000216927.4
ENST00000344103.4
SIRPG
signal-regulatory protein gamma
chr14_-_23285011 6.01 ENST00000397532.3
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr19_-_39108552 5.97 ENST00000591517.1
MAP4K1
mitogen-activated protein kinase kinase kinase kinase 1
chr7_+_74188309 5.96 ENST00000289473.4
ENST00000433458.1
NCF1
neutrophil cytosolic factor 1
chr6_-_41122063 5.89 ENST00000426005.2
ENST00000437044.2
ENST00000373127.4
TREML1
triggering receptor expressed on myeloid cells-like 1
chr1_+_111415757 5.89 ENST00000429072.2
ENST00000271324.5
CD53
CD53 molecule
chr6_+_391739 5.88 ENST00000380956.4
IRF4
interferon regulatory factor 4
chr19_+_51645556 5.86 ENST00000601682.1
ENST00000317643.6
ENST00000305628.7
ENST00000600577.1
SIGLEC7
sialic acid binding Ig-like lectin 7
chr19_-_52307357 5.81 ENST00000594900.1
FPR1
formyl peptide receptor 1
chr3_+_32433363 5.74 ENST00000465248.1
CMTM7
CKLF-like MARVEL transmembrane domain containing 7
chr1_-_150738261 5.74 ENST00000448301.2
ENST00000368985.3
CTSS
cathepsin S
chr6_+_31554636 5.73 ENST00000433492.1
LST1
leukocyte specific transcript 1
chr17_+_72462766 5.70 ENST00000392625.3
ENST00000361933.3
ENST00000310828.5
CD300A
CD300a molecule
chr22_+_37257015 5.64 ENST00000447071.1
ENST00000248899.6
ENST00000397147.4
NCF4
neutrophil cytosolic factor 4, 40kDa
chr17_-_37934466 5.52 ENST00000583368.1
IKZF3
IKAROS family zinc finger 3 (Aiolos)
chr12_+_54891495 5.50 ENST00000293373.6
NCKAP1L
NCK-associated protein 1-like
chr14_-_23285069 5.40 ENST00000554758.1
ENST00000397528.4
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr6_+_31554456 5.34 ENST00000339530.4
LST1
leukocyte specific transcript 1
chr19_-_10450287 5.31 ENST00000589261.1
ENST00000590569.1
ENST00000589580.1
ENST00000589249.1
ICAM3
intercellular adhesion molecule 3
chr3_+_32433154 5.25 ENST00000334983.5
ENST00000349718.4
CMTM7
CKLF-like MARVEL transmembrane domain containing 7
chr7_-_115799942 5.25 ENST00000484212.1
TFEC
transcription factor EC
chr1_-_160549235 5.22 ENST00000368054.3
ENST00000368048.3
ENST00000311224.4
ENST00000368051.3
ENST00000534968.1
CD84
CD84 molecule
chr12_+_7055767 5.21 ENST00000447931.2
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr5_-_149465990 5.21 ENST00000543093.1
CSF1R
colony stimulating factor 1 receptor
chr16_+_81812863 5.20 ENST00000359376.3
PLCG2
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr1_-_161519579 5.17 ENST00000426740.1
FCGR3A
Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
chr9_+_273038 5.17 ENST00000487230.1
ENST00000469391.1
DOCK8
dedicator of cytokinesis 8
chr19_-_7766991 5.17 ENST00000597921.1
ENST00000346664.5
FCER2
Fc fragment of IgE, low affinity II, receptor for (CD23)
chr16_+_57576584 5.15 ENST00000340339.4
GPR114
G protein-coupled receptor 114
chr22_-_37880543 5.15 ENST00000442496.1
MFNG
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr1_-_183560011 5.09 ENST00000367536.1
NCF2
neutrophil cytosolic factor 2
chr17_-_29641104 5.06 ENST00000577894.1
ENST00000330927.4
EVI2B
ecotropic viral integration site 2B
chr1_+_40810516 5.05 ENST00000435168.2
SMAP2
small ArfGAP2
chr17_+_34431212 5.05 ENST00000394495.1
CCL4
chemokine (C-C motif) ligand 4
chr2_+_218994002 5.04 ENST00000428565.1
CXCR2
chemokine (C-X-C motif) receptor 2
chr14_+_21423611 5.03 ENST00000304625.2
RNASE2
ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
chr17_-_29641084 5.03 ENST00000544462.1
EVI2B
ecotropic viral integration site 2B
chr12_-_8218926 5.01 ENST00000546241.1
C3AR1
complement component 3a receptor 1
chr12_+_25205666 4.99 ENST00000547044.1
LRMP
lymphoid-restricted membrane protein
chr19_-_10450328 4.97 ENST00000160262.5
ICAM3
intercellular adhesion molecule 3
chr2_+_233924548 4.95 ENST00000422935.1
INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr19_+_35939154 4.95 ENST00000599180.2
FFAR2
free fatty acid receptor 2
chr16_-_21663919 4.93 ENST00000569602.1
IGSF6
immunoglobulin superfamily, member 6
chr1_-_161519682 4.93 ENST00000367969.3
ENST00000443193.1
FCGR3A
Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
chr3_+_52321827 4.90 ENST00000473032.1
ENST00000305690.8
ENST00000354773.4
ENST00000471180.1
ENST00000436784.2
GLYCTK
glycerate kinase
chr11_-_59951430 4.85 ENST00000533409.1
MS4A6A
membrane-spanning 4-domains, subfamily A, member 6A
chr4_-_103682071 4.83 ENST00000505239.1
MANBA
mannosidase, beta A, lysosomal
chr10_+_26727333 4.80 ENST00000356785.4
APBB1IP
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr16_-_21663950 4.79 ENST00000268389.4
IGSF6
immunoglobulin superfamily, member 6
chr16_+_31271274 4.74 ENST00000287497.8
ENST00000544665.3
ITGAM
integrin, alpha M (complement component 3 receptor 3 subunit)
chr2_-_64568781 4.69 ENST00000424119.1
AC114752.3
AC114752.3
chr12_-_8218997 4.60 ENST00000307637.4
C3AR1
complement component 3a receptor 1
chr1_+_241695424 4.58 ENST00000366558.3
ENST00000366559.4
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr21_-_15918618 4.57 ENST00000400564.1
ENST00000400566.1
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr12_+_7055631 4.54 ENST00000543115.1
ENST00000399448.1
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr17_-_20370847 4.52 ENST00000423676.3
ENST00000324290.5
LGALS9B
lectin, galactoside-binding, soluble, 9B
chr5_+_96211643 4.52 ENST00000437043.3
ENST00000510373.1
ERAP2
endoplasmic reticulum aminopeptidase 2
chr12_-_15114603 4.50 ENST00000228945.4
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr20_+_48884002 4.50 ENST00000425497.1
ENST00000445003.1
RP11-290F20.3
RP11-290F20.3
chr1_+_161475208 4.49 ENST00000367972.4
ENST00000271450.6
FCGR2A
Fc fragment of IgG, low affinity IIa, receptor (CD32)
chr12_+_105724613 4.47 ENST00000549934.2
C12orf75
chromosome 12 open reading frame 75
chr2_-_89545079 4.45 ENST00000468494.1
IGKV2-30
immunoglobulin kappa variable 2-30
chr19_-_51920835 4.43 ENST00000442846.3
ENST00000530476.1
SIGLEC10
sialic acid binding Ig-like lectin 10
chr12_-_15114658 4.42 ENST00000542276.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr19_+_6772710 4.41 ENST00000304076.2
ENST00000602142.1
ENST00000596764.1
VAV1
vav 1 guanine nucleotide exchange factor
chr6_+_36973406 4.39 ENST00000274963.8
FGD2
FYVE, RhoGEF and PH domain containing 2
chr2_+_113885138 4.35 ENST00000409930.3
IL1RN
interleukin 1 receptor antagonist
chr12_+_25205628 4.34 ENST00000554942.1
LRMP
lymphoid-restricted membrane protein
chr12_+_8608522 4.28 ENST00000382073.3
CLEC6A
C-type lectin domain family 6, member A
chr1_+_196912902 4.28 ENST00000476712.2
ENST00000367415.5
CFHR2
complement factor H-related 2
chr15_-_80263506 4.26 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr4_+_68424434 4.25 ENST00000265404.2
ENST00000396225.1
STAP1
signal transducing adaptor family member 1
chr6_+_31553978 4.24 ENST00000376096.1
ENST00000376099.1
ENST00000376110.3
LST1
leukocyte specific transcript 1
chr5_+_57787254 4.23 ENST00000502276.1
ENST00000396776.2
ENST00000511930.1
GAPT
GRB2-binding adaptor protein, transmembrane
chr2_+_202125219 4.21 ENST00000323492.7
CASP8
caspase 8, apoptosis-related cysteine peptidase
chr12_+_47610315 4.20 ENST00000548348.1
ENST00000549500.1
PCED1B
PC-esterase domain containing 1B
chr3_+_121796697 4.19 ENST00000482356.1
ENST00000393627.2
CD86
CD86 molecule
chr19_-_54804173 4.18 ENST00000391744.3
ENST00000251390.3
LILRA3
leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3
chr1_-_31230650 4.17 ENST00000294507.3
LAPTM5
lysosomal protein transmembrane 5
chr16_-_68034452 4.17 ENST00000575510.1
DPEP2
dipeptidase 2
chr15_+_77287426 4.16 ENST00000558012.1
ENST00000267939.5
ENST00000379595.3
PSTPIP1
proline-serine-threonine phosphatase interacting protein 1
chr19_-_6481759 4.15 ENST00000588421.1
DENND1C
DENN/MADD domain containing 1C
chr19_+_35940486 4.13 ENST00000246549.2
FFAR2
free fatty acid receptor 2
chr7_+_150264365 4.13 ENST00000255945.2
ENST00000461940.1
GIMAP4
GTPase, IMAP family member 4
chr20_-_1569278 4.10 ENST00000262929.5
ENST00000567028.1
SIRPB1
RP4-576H24.4
signal-regulatory protein beta 1
Uncharacterized protein
chr6_-_6225026 4.08 ENST00000445223.1
F13A1
coagulation factor XIII, A1 polypeptide
chr1_+_161551101 4.06 ENST00000367962.4
ENST00000367960.5
ENST00000403078.3
ENST00000428605.2
FCGR2B
Fc fragment of IgG, low affinity IIb, receptor (CD32)
chr3_-_121379739 4.05 ENST00000428394.2
ENST00000314583.3
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr13_+_31309645 4.04 ENST00000380490.3
ALOX5AP
arachidonate 5-lipoxygenase-activating protein
chr19_-_36233332 4.04 ENST00000592537.1
ENST00000246532.1
ENST00000344990.3
ENST00000588992.1
IGFLR1
IGF-like family receptor 1
chr4_+_8201091 3.99 ENST00000382521.3
ENST00000245105.3
ENST00000457650.2
ENST00000539824.1
SH3TC1
SH3 domain and tetratricopeptide repeats 1
chr1_+_161632937 3.98 ENST00000236937.9
ENST00000367961.4
ENST00000358671.5
FCGR2B
Fc fragment of IgG, low affinity IIb, receptor (CD32)
chr5_-_180235755 3.97 ENST00000502678.1
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr6_+_31582961 3.94 ENST00000376059.3
ENST00000337917.7
AIF1
allograft inflammatory factor 1
chr17_-_72542278 3.93 ENST00000330793.1
CD300C
CD300c molecule
chr4_+_74606223 3.90 ENST00000307407.3
ENST00000401931.1
IL8
interleukin 8
chr19_-_6481776 3.88 ENST00000543576.1
ENST00000590173.1
ENST00000381480.2
DENND1C
DENN/MADD domain containing 1C
chr18_-_61089611 3.84 ENST00000591519.1
VPS4B
vacuolar protein sorting 4 homolog B (S. cerevisiae)
chr1_+_149230680 3.83 ENST00000443018.1
RP11-403I13.5
RP11-403I13.5
chr19_-_14887568 3.82 ENST00000596991.2
ENST00000594294.1
ENST00000594076.1
ENST00000595839.1
ENST00000392965.3
ENST00000601345.1
EMR2
egf-like module containing, mucin-like, hormone receptor-like 2
chr21_-_46340807 3.80 ENST00000397846.3
ENST00000524251.1
ENST00000522688.1
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr2_+_143886877 3.76 ENST00000295095.6
ARHGAP15
Rho GTPase activating protein 15
chr17_+_7482785 3.76 ENST00000250092.6
ENST00000380498.6
ENST00000584502.1
CD68
CD68 molecule
chr19_-_18508396 3.74 ENST00000595840.1
ENST00000339007.3
LRRC25
leucine rich repeat containing 25
chr21_-_46340884 3.74 ENST00000302347.5
ENST00000517819.1
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr19_-_51920873 3.71 ENST00000441969.3
ENST00000525998.1
ENST00000436984.2
SIGLEC10
sialic acid binding Ig-like lectin 10
chr19_-_39826639 3.71 ENST00000602185.1
ENST00000598034.1
ENST00000601387.1
ENST00000595636.1
ENST00000253054.8
ENST00000594700.1
ENST00000597595.1
GMFG
glia maturation factor, gamma
chr2_+_181988620 3.70 ENST00000428474.1
ENST00000424655.1
AC104820.2
AC104820.2
chr19_+_46010674 3.70 ENST00000245932.6
ENST00000592139.1
ENST00000590603.1
VASP
vasodilator-stimulated phosphoprotein
chr11_+_64107663 3.69 ENST00000356786.5
CCDC88B
coiled-coil domain containing 88B
chr16_-_88717482 3.69 ENST00000261623.3
CYBA
cytochrome b-245, alpha polypeptide
chr19_+_55128576 3.68 ENST00000396331.1
LILRB1
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chr13_+_43148281 3.68 ENST00000239849.6
ENST00000398795.2
ENST00000544862.1
TNFSF11
tumor necrosis factor (ligand) superfamily, member 11
chr8_+_27169138 3.68 ENST00000522338.1
PTK2B
protein tyrosine kinase 2 beta
chr15_+_77287715 3.67 ENST00000559161.1
PSTPIP1
proline-serine-threonine phosphatase interacting protein 1
chr14_-_106114739 3.66 ENST00000460164.1
RP11-731F5.2
RP11-731F5.2
chr19_-_51920952 3.65 ENST00000356298.5
ENST00000339313.5
ENST00000529627.1
ENST00000439889.2
ENST00000353836.5
ENST00000432469.2
SIGLEC10
sialic acid binding Ig-like lectin 10
chr12_+_7060508 3.65 ENST00000541698.1
ENST00000542462.1
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chrY_+_2709527 3.64 ENST00000250784.8
RPS4Y1
ribosomal protein S4, Y-linked 1
chr1_+_112016414 3.62 ENST00000343534.5
ENST00000369718.3
C1orf162
chromosome 1 open reading frame 162
chr1_-_157522180 3.61 ENST00000356953.4
ENST00000368188.2
ENST00000368190.3
ENST00000368189.3
FCRL5
Fc receptor-like 5
chr16_+_66613351 3.59 ENST00000379486.2
ENST00000268595.2
CMTM2
CKLF-like MARVEL transmembrane domain containing 2
chr1_-_157522260 3.58 ENST00000368191.3
ENST00000361835.3
FCRL5
Fc receptor-like 5
chr14_-_106518922 3.58 ENST00000390598.2
IGHV3-7
immunoglobulin heavy variable 3-7
chr1_+_117544366 3.55 ENST00000256652.4
ENST00000369470.1
CD101
CD101 molecule
chr1_-_183559693 3.55 ENST00000367535.3
ENST00000413720.1
ENST00000418089.1
NCF2
neutrophil cytosolic factor 2
chr2_-_113594279 3.53 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
IL1B
interleukin 1, beta
chr20_+_43595115 3.53 ENST00000372806.3
ENST00000396731.4
ENST00000372801.1
ENST00000499879.2
STK4
serine/threonine kinase 4
chr16_-_88851618 3.46 ENST00000301015.9
PIEZO1
piezo-type mechanosensitive ion channel component 1
chr5_-_140013224 3.45 ENST00000498971.2
CD14
CD14 molecule
chr3_+_52813932 3.45 ENST00000537050.1
ITIH1
inter-alpha-trypsin inhibitor heavy chain 1
chr20_-_3687775 3.43 ENST00000344754.4
ENST00000202578.4
SIGLEC1
sialic acid binding Ig-like lectin 1, sialoadhesin
chr19_-_52133588 3.42 ENST00000570106.2
SIGLEC5
sialic acid binding Ig-like lectin 5
chr5_-_78281603 3.38 ENST00000264914.4
ARSB
arylsulfatase B
chr12_+_7060414 3.37 ENST00000538715.1
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr4_-_164534657 3.36 ENST00000339875.5
MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr19_+_55141861 3.36 ENST00000396327.3
ENST00000324602.7
ENST00000434867.2
LILRB1
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chr5_-_140013275 3.36 ENST00000512545.1
ENST00000302014.6
ENST00000401743.2
CD14
CD14 molecule
chr19_+_35645618 3.34 ENST00000392218.2
ENST00000543307.1
ENST00000392219.2
ENST00000541435.2
ENST00000590686.1
ENST00000342879.3
ENST00000588699.1
FXYD5
FXYD domain containing ion transport regulator 5

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
8.6 25.7 GO:0034125 negative regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034125)
6.0 18.1 GO:0061485 memory T cell proliferation(GO:0061485)
4.5 13.4 GO:0002337 B-1a B cell differentiation(GO:0002337)
4.2 16.7 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
3.4 10.1 GO:0045404 positive regulation of interleukin-4 biosynthetic process(GO:0045404)
3.3 13.2 GO:0002316 follicular B cell differentiation(GO:0002316)
3.2 18.9 GO:0033277 abortive mitotic cell cycle(GO:0033277)
3.1 31.2 GO:0000821 regulation of arginine metabolic process(GO:0000821)
3.0 9.1 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
2.5 10.1 GO:0002290 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
2.3 7.0 GO:0061582 colon epithelial cell migration(GO:0061580) intestinal epithelial cell migration(GO:0061582)
2.3 11.5 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
2.3 13.7 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
2.3 6.8 GO:1990654 sebum secreting cell proliferation(GO:1990654)
2.2 6.7 GO:0050904 diapedesis(GO:0050904)
2.2 11.0 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
2.1 14.8 GO:0071461 cellular response to redox state(GO:0071461)
2.0 10.1 GO:0039513 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
1.9 5.8 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
1.8 7.2 GO:0002774 Fc receptor mediated inhibitory signaling pathway(GO:0002774)
1.8 1.8 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
1.7 8.4 GO:0032796 uropod organization(GO:0032796)
1.6 6.3 GO:1903542 negative regulation of exosomal secretion(GO:1903542) regulation of centriole elongation(GO:1903722)
1.4 10.0 GO:0071727 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
1.4 4.3 GO:1903980 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973) positive regulation of microglial cell activation(GO:1903980)
1.4 7.0 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
1.3 5.2 GO:0032661 regulation of interleukin-18 production(GO:0032661)
1.3 3.8 GO:0070902 mitochondrial tRNA pseudouridine synthesis(GO:0070902)
1.2 3.7 GO:0019085 early viral transcription(GO:0019085)
1.2 3.7 GO:0071810 positive regulation of corticotropin-releasing hormone secretion(GO:0051466) regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
1.2 3.5 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
1.2 3.5 GO:0046136 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
1.2 3.5 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
1.1 3.2 GO:1901076 positive regulation of engulfment of apoptotic cell(GO:1901076)
1.0 7.3 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
1.0 5.2 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
1.0 3.1 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
1.0 13.0 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.9 9.5 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.9 5.7 GO:0030581 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.9 22.7 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.9 6.1 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.9 2.6 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.9 15.4 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.9 6.8 GO:0010266 response to vitamin B1(GO:0010266)
0.8 5.0 GO:0038112 interleukin-8-mediated signaling pathway(GO:0038112)
0.8 4.9 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.8 7.1 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.8 22.0 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.8 2.3 GO:0002399 MHC class II protein complex assembly(GO:0002399)
0.8 5.3 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.7 5.1 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.7 3.6 GO:0019086 late viral transcription(GO:0019086)
0.7 4.3 GO:0036510 trimming of terminal mannose on C branch(GO:0036510)
0.7 2.8 GO:0033625 positive regulation of integrin activation(GO:0033625)
0.7 13.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.7 1.3 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.7 4.6 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.6 0.6 GO:1902954 regulation of early endosome to recycling endosome transport(GO:1902954)
0.6 23.0 GO:0045730 respiratory burst(GO:0045730)
0.6 3.7 GO:2000538 regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.6 1.2 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.6 3.5 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.6 1.7 GO:0046963 3'-phosphoadenosine 5'-phosphosulfate transport(GO:0046963) 3'-phospho-5'-adenylyl sulfate transmembrane transport(GO:1902559)
0.6 2.3 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.6 3.4 GO:0001692 histamine metabolic process(GO:0001692)
0.6 3.9 GO:0014738 regulation of muscle hyperplasia(GO:0014738)
0.6 1.1 GO:0036369 transcription factor catabolic process(GO:0036369)
0.6 19.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.5 9.5 GO:0015939 pantothenate metabolic process(GO:0015939)
0.5 2.6 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.5 5.2 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.5 2.1 GO:0036071 N-glycan fucosylation(GO:0036071)
0.5 2.1 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.5 1.5 GO:0045354 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.5 6.0 GO:0045651 positive regulation of macrophage differentiation(GO:0045651)
0.5 1.5 GO:0097359 UDP-glucosylation(GO:0097359)
0.5 1.0 GO:0032641 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.5 2.9 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.5 1.4 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.5 1.4 GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.4 3.1 GO:0006710 androgen catabolic process(GO:0006710)
0.4 4.0 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.4 2.2 GO:0042631 cellular response to water deprivation(GO:0042631)
0.4 0.9 GO:0045410 positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.4 1.7 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.4 1.7 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.4 5.0 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.4 1.2 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.4 2.5 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.4 2.0 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.4 1.2 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.4 0.8 GO:0043335 protein unfolding(GO:0043335)
0.4 1.5 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.4 7.6 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.4 13.3 GO:0010447 response to acidic pH(GO:0010447)
0.4 1.1 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.4 2.9 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.4 2.9 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.4 4.4 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.4 2.9 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.4 3.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.4 2.9 GO:0070383 DNA cytosine deamination(GO:0070383)
0.3 1.0 GO:0072717 response to actinomycin D(GO:0072716) cellular response to actinomycin D(GO:0072717)
0.3 3.8 GO:1902961 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.3 2.4 GO:1904721 negative regulation of mRNA cleavage(GO:0031438) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.3 1.7 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.3 3.4 GO:2001300 lipoxin metabolic process(GO:2001300)
0.3 3.4 GO:0038129 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.3 2.0 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.3 1.0 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.3 5.3 GO:0001955 blood vessel maturation(GO:0001955)
0.3 1.9 GO:0061188 negative regulation of chromatin silencing at rDNA(GO:0061188)
0.3 33.6 GO:0032945 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.3 1.6 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.3 4.3 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.3 5.5 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.3 1.5 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.3 3.6 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.3 1.4 GO:0060684 epithelial-mesenchymal cell signaling(GO:0060684)
0.3 6.1 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.3 6.4 GO:0010818 T cell chemotaxis(GO:0010818)
0.3 1.1 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.3 1.9 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.3 0.8 GO:0038163 endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163)
0.3 5.9 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.3 1.3 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.2 2.9 GO:0061042 vascular wound healing(GO:0061042)
0.2 1.9 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.2 3.1 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.2 2.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.2 3.8 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.2 1.9 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.2 1.4 GO:0006611 protein export from nucleus(GO:0006611)
0.2 4.6 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.2 0.7 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.2 1.8 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.2 1.3 GO:1903436 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.2 50.2 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.2 0.6 GO:0046041 ITP metabolic process(GO:0046041)
0.2 5.8 GO:0045577 regulation of B cell differentiation(GO:0045577)
0.2 3.0 GO:0042989 sequestering of actin monomers(GO:0042989)
0.2 4.0 GO:0042832 defense response to protozoan(GO:0042832)
0.2 6.5 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.2 1.2 GO:0035063 nuclear speck organization(GO:0035063)
0.2 1.0 GO:0072709 cellular response to sorbitol(GO:0072709)
0.2 1.9 GO:0070995 NADPH oxidation(GO:0070995)
0.2 0.8 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.2 1.8 GO:0051852 disruption by host of symbiont cells(GO:0051852) killing by host of symbiont cells(GO:0051873)
0.2 2.4 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.2 0.8 GO:0045006 DNA deamination(GO:0045006)
0.2 2.0 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.2 2.8 GO:0038171 cannabinoid signaling pathway(GO:0038171)
0.2 1.2 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.2 4.7 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.2 1.0 GO:0006045 N-acetylglucosamine biosynthetic process(GO:0006045) glucosamine-containing compound biosynthetic process(GO:1901073)
0.2 3.5 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.2 2.9 GO:0090168 Golgi reassembly(GO:0090168)
0.2 1.5 GO:0080009 mRNA methylation(GO:0080009)
0.2 1.3 GO:0090023 positive regulation of granulocyte chemotaxis(GO:0071624) positive regulation of neutrophil chemotaxis(GO:0090023)
0.2 0.7 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.2 0.7 GO:0010628 positive regulation of gene expression(GO:0010628)
0.2 0.4 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.2 13.1 GO:0006968 cellular defense response(GO:0006968)
0.2 0.7 GO:0007418 ventral midline development(GO:0007418) smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938) notochord regression(GO:0060032)
0.2 1.6 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.2 0.9 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.2 6.3 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.2 1.0 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.2 3.1 GO:0033160 positive regulation of protein import into nucleus, translocation(GO:0033160)
0.2 5.1 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.2 0.2 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.2 1.2 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.2 2.1 GO:0006477 protein sulfation(GO:0006477)
0.2 1.1 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.2 0.5 GO:0034444 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.2 0.8 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.2 1.4 GO:0048505 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.2 1.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.2 1.4 GO:0035655 interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351)
0.2 13.3 GO:0042100 B cell proliferation(GO:0042100)
0.2 0.6 GO:0036229 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.2 1.4 GO:0007000 nucleolus organization(GO:0007000)
0.1 1.8 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.7 GO:1902570 protein localization to nucleolus(GO:1902570)
0.1 1.0 GO:1903352 L-ornithine transmembrane transport(GO:1903352)
0.1 8.8 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742)
0.1 0.6 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.1 1.0 GO:0002923 regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002923)
0.1 1.3 GO:0006565 L-serine catabolic process(GO:0006565)
0.1 3.5 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 0.4 GO:0001546 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.1 4.3 GO:0050832 defense response to fungus(GO:0050832)
0.1 1.4 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 1.7 GO:1901740 negative regulation of myoblast fusion(GO:1901740) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 0.5 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 8.2 GO:0043171 peptide catabolic process(GO:0043171)
0.1 5.0 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.1 1.1 GO:0043473 pigmentation(GO:0043473)
0.1 0.5 GO:0015883 FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
0.1 2.9 GO:0051923 sulfation(GO:0051923)
0.1 0.8 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 2.7 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 3.8 GO:0043101 purine-containing compound salvage(GO:0043101)
0.1 0.9 GO:0051270 regulation of cellular component movement(GO:0051270)
0.1 1.8 GO:0070857 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127) regulation of bile acid biosynthetic process(GO:0070857)
0.1 2.0 GO:0015693 magnesium ion transport(GO:0015693)
0.1 19.1 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 2.9 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.1 1.3 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.6 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.1 1.4 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 2.1 GO:0019388 galactose catabolic process(GO:0019388)
0.1 1.5 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.1 1.3 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 1.8 GO:0021860 pyramidal neuron development(GO:0021860)
0.1 2.3 GO:0036344 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.1 0.9 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 1.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.9 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.1 0.5 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.1 0.5 GO:2001140 regulation of phospholipid transport(GO:2001138) positive regulation of phospholipid transport(GO:2001140)
0.1 4.2 GO:0018345 protein palmitoylation(GO:0018345)
0.1 1.3 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.1 1.9 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.1 1.4 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
0.1 1.1 GO:0060613 fat pad development(GO:0060613)
0.1 0.6 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.1 1.3 GO:0071285 cellular response to lithium ion(GO:0071285)
0.1 1.2 GO:0016180 snRNA processing(GO:0016180)
0.1 0.4 GO:0006447 regulation of translational initiation by iron(GO:0006447)
0.1 16.5 GO:0002220 innate immune response activating cell surface receptor signaling pathway(GO:0002220)
0.1 0.7 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1 0.5 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 6.7 GO:0030183 B cell differentiation(GO:0030183)
0.1 1.9 GO:0030100 regulation of endocytosis(GO:0030100)
0.1 2.2 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 0.7 GO:0006983 ER overload response(GO:0006983)
0.1 1.8 GO:0051255 spindle midzone assembly(GO:0051255)
0.1 0.9 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.1 1.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 3.5 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.1 0.2 GO:1990637 response to prolactin(GO:1990637)
0.1 2.2 GO:0007035 vacuolar acidification(GO:0007035)
0.1 5.6 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 1.6 GO:0090161 Golgi ribbon formation(GO:0090161)
0.1 0.4 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 1.7 GO:0032886 regulation of microtubule-based process(GO:0032886)
0.1 0.9 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1 0.5 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 5.5 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 1.3 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.1 0.6 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 1.8 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.1 1.5 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.1 1.8 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.1 1.7 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.1 0.2 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.1 1.6 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 1.4 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 1.0 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.1 0.7 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 1.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.3 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.1 2.0 GO:0070932 histone H3 deacetylation(GO:0070932)
0.1 7.2 GO:0002819 regulation of adaptive immune response(GO:0002819)
0.1 0.9 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.1 0.3 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.1 1.4 GO:0051382 kinetochore assembly(GO:0051382)
0.1 9.1 GO:0002250 adaptive immune response(GO:0002250)
0.1 1.0 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 3.5 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 0.5 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.1 5.0 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.1 0.9 GO:1902593 single-organism nuclear import(GO:1902593)
0.1 2.7 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.5 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.1 0.8 GO:0035973 aggrephagy(GO:0035973)
0.1 1.1 GO:0002115 store-operated calcium entry(GO:0002115)
0.1 1.4 GO:0006853 carnitine shuttle(GO:0006853)
0.1 0.7 GO:0034205 beta-amyloid formation(GO:0034205)
0.1 1.2 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.1 0.2 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.1 0.2 GO:0019046 release from viral latency(GO:0019046)
0.1 0.3 GO:1902513 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323) regulation of organelle transport along microtubule(GO:1902513)
0.1 1.2 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 0.2 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 0.7 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.1 7.6 GO:0006903 vesicle targeting(GO:0006903)
0.1 2.4 GO:0036297 interstrand cross-link repair(GO:0036297)
0.1 0.7 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.7 GO:0033197 response to vitamin E(GO:0033197)
0.1 1.1 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 12.2 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 1.6 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 15.8 GO:0045087 innate immune response(GO:0045087)
0.0 1.9 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 1.8 GO:0006110 regulation of glycolytic process(GO:0006110)
0.0 0.7 GO:0015866 ADP transport(GO:0015866)
0.0 0.6 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.3 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 2.7 GO:0043507 positive regulation of JUN kinase activity(GO:0043507)
0.0 1.0 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.5 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.7 GO:0042737 drug catabolic process(GO:0042737)
0.0 0.5 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 1.4 GO:0000732 strand displacement(GO:0000732)
0.0 0.2 GO:0035357 peroxisome proliferator activated receptor signaling pathway(GO:0035357)
0.0 0.7 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 4.0 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 25.1 GO:0050776 regulation of immune response(GO:0050776)
0.0 3.8 GO:0035690 cellular response to drug(GO:0035690)
0.0 6.5 GO:0021987 cerebral cortex development(GO:0021987)
0.0 2.7 GO:0050870 positive regulation of T cell activation(GO:0050870)
0.0 1.3 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 1.6 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 1.7 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.3 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.7 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 1.0 GO:0009435 NAD biosynthetic process(GO:0009435)
0.0 0.1 GO:0030047 actin modification(GO:0030047)
0.0 0.4 GO:0008334 histone mRNA metabolic process(GO:0008334)
0.0 0.2 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.0 3.2 GO:0051289 protein homotetramerization(GO:0051289)
0.0 1.0 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.0 0.7 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0 2.4 GO:0010833 telomere maintenance via telomere lengthening(GO:0010833)
0.0 0.3 GO:0090043 tubulin deacetylation(GO:0090042) regulation of tubulin deacetylation(GO:0090043)
0.0 0.1 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 3.8 GO:1990823 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.6 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.4 GO:0045116 protein neddylation(GO:0045116)
0.0 0.6 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.8 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.3 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.9 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.4 GO:0060134 prepulse inhibition(GO:0060134)
0.0 1.0 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652)
0.0 0.1 GO:0044829 positive regulation by host of viral genome replication(GO:0044829) regulation of post-translational protein modification(GO:1901873)
0.0 3.9 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.3 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.0 0.4 GO:0015747 urate transport(GO:0015747)
0.0 2.1 GO:0009060 aerobic respiration(GO:0009060)
0.0 2.4 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.4 GO:0045023 G0 to G1 transition(GO:0045023)
0.0 0.2 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.7 GO:0033146 regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
0.0 0.1 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.4 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.3 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.5 GO:0006953 acute-phase response(GO:0006953)
0.0 0.5 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 1.9 GO:0051607 defense response to virus(GO:0051607)
0.0 0.9 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.7 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.0 1.1 GO:0060976 coronary vasculature development(GO:0060976)
0.0 0.3 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 1.3 GO:0071774 response to fibroblast growth factor(GO:0071774)
0.0 0.6 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 0.5 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.4 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 1.9 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 1.0 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 1.7 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.6 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.4 GO:0019985 translesion synthesis(GO:0019985)
0.0 1.9 GO:0007127 meiosis I(GO:0007127)
0.0 1.2 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.5 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.5 GO:0002092 positive regulation of receptor internalization(GO:0002092)
0.0 0.3 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.7 GO:0050919 negative chemotaxis(GO:0050919)
0.0 2.2 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.0 GO:0090283 negative regulation of protein glycosylation(GO:0060051) regulation of protein glycosylation in Golgi(GO:0090283) negative regulation of protein glycosylation in Golgi(GO:0090285)
0.0 0.3 GO:1903203 regulation of oxidative stress-induced neuron death(GO:1903203) negative regulation of oxidative stress-induced neuron death(GO:1903204)
0.0 0.5 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 1.1 GO:0050709 negative regulation of protein secretion(GO:0050709)
0.0 0.8 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) response to interleukin-12(GO:0070671) cellular response to interleukin-12(GO:0071349)
0.0 0.5 GO:0042255 ribosome assembly(GO:0042255)
0.0 0.1 GO:0042350 GDP-L-fucose biosynthetic process(GO:0042350)
0.0 0.4 GO:0045595 regulation of cell differentiation(GO:0045595)
0.0 2.0 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 1.6 GO:0007269 neurotransmitter secretion(GO:0007269) signal release from synapse(GO:0099643)
0.0 0.1 GO:0044818 mitotic G2/M transition checkpoint(GO:0044818)
0.0 0.3 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 0.3 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0 0.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.6 GO:0015804 neutral amino acid transport(GO:0015804)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.1 GO:0030526 granulocyte macrophage colony-stimulating factor receptor complex(GO:0030526)
2.1 8.2 GO:0034687 integrin alphaL-beta2 complex(GO:0034687)
2.1 20.5 GO:0032010 phagolysosome(GO:0032010)
1.9 15.5 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
1.5 20.0 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
1.5 10.7 GO:0019815 B cell receptor complex(GO:0019815)
1.5 13.4 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
1.4 5.7 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
1.3 6.7 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
1.1 20.3 GO:0031209 SCAR complex(GO:0031209)
0.8 5.6 GO:0036021 endolysosome lumen(GO:0036021)
0.7 5.2 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.7 2.7 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.7 2.0 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.6 2.6 GO:0031084 BLOC-2 complex(GO:0031084)
0.6 2.4 GO:0031251 PAN complex(GO:0031251)
0.5 3.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.5 0.5 GO:0071817 MMXD complex(GO:0071817)
0.5 10.5 GO:0016461 unconventional myosin complex(GO:0016461)
0.5 3.0 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.5 11.8 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.5 16.8 GO:0001891 phagocytic cup(GO:0001891)
0.4 1.3 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.4 7.0 GO:0043020 NADPH oxidase complex(GO:0043020)
0.4 3.0 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.4 10.9 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.4 2.8 GO:1902560 GMP reductase complex(GO:1902560)
0.4 1.2 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
0.4 43.8 GO:0035577 azurophil granule membrane(GO:0035577)
0.4 1.5 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.4 0.8 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.4 1.9 GO:1990031 pinceau fiber(GO:1990031)
0.4 5.9 GO:0000788 nuclear nucleosome(GO:0000788)
0.3 31.0 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.3 1.0 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.3 1.3 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.3 3.6 GO:0016589 NURF complex(GO:0016589)
0.3 1.5 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.3 0.9 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.3 6.1 GO:0090543 Flemming body(GO:0090543)
0.3 1.8 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.3 1.2 GO:0071001 U4/U6 snRNP(GO:0071001)
0.3 1.4 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.2 1.7 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.2 1.4 GO:0000799 nuclear condensin complex(GO:0000799)
0.2 12.0 GO:0001772 immunological synapse(GO:0001772)
0.2 4.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.2 1.8 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.2 1.3 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.2 1.7 GO:0070435 Shc-EGFR complex(GO:0070435)
0.2 4.8 GO:0042101 T cell receptor complex(GO:0042101)
0.2 0.8 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.2 2.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.2 2.7 GO:0005577 fibrinogen complex(GO:0005577)
0.2 4.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.2 0.8 GO:0097635 extrinsic component of autophagosome membrane(GO:0097635)
0.2 76.9 GO:0009897 external side of plasma membrane(GO:0009897)
0.2 17.2 GO:1904724 tertiary granule lumen(GO:1904724)
0.2 1.1 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.2 0.9 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.2 7.2 GO:0031258 lamellipodium membrane(GO:0031258)
0.2 1.7 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.2 4.0 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.2 2.7 GO:0032039 integrator complex(GO:0032039)
0.2 2.1 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2 0.5 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 0.9 GO:0097149 centralspindlin complex(GO:0097149)
0.1 2.0 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 2.4 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 2.1 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.1 3.5 GO:0042627 chylomicron(GO:0042627)
0.1 17.0 GO:0035578 azurophil granule lumen(GO:0035578)
0.1 1.2 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 1.6 GO:0044754 autolysosome(GO:0044754)
0.1 1.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 0.5 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 1.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 4.0 GO:0042629 mast cell granule(GO:0042629)
0.1 0.6 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.1 0.8 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 2.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 1.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 12.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.1 GO:0071159 NF-kappaB complex(GO:0071159)
0.1 3.4 GO:0030686 90S preribosome(GO:0030686)
0.1 7.3 GO:0031201 SNARE complex(GO:0031201)
0.1 9.4 GO:0005811 lipid particle(GO:0005811)
0.1 0.2 GO:0019034 viral replication complex(GO:0019034)
0.1 1.0 GO:0042382 paraspeckles(GO:0042382)
0.1 7.9 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
0.1 13.5 GO:0031091 platelet alpha granule(GO:0031091)
0.1 0.5 GO:0097452 GAIT complex(GO:0097452)
0.1 6.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 2.1 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 3.5 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 2.2 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 0.5 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 2.1 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.3 GO:0055087 Ski complex(GO:0055087)
0.1 1.2 GO:0033269 internode region of axon(GO:0033269)
0.1 17.5 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.3 GO:0070938 contractile ring(GO:0070938)
0.1 3.8 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 1.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.7 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 0.6 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 0.7 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 0.2 GO:0035189 Rb-E2F complex(GO:0035189)
0.1 1.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 11.7 GO:0072562 blood microparticle(GO:0072562)
0.1 1.6 GO:0035102 PRC1 complex(GO:0035102)
0.1 0.5 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.8 GO:0072487 MSL complex(GO:0072487)
0.1 0.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 1.0 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 0.4 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.1 0.4 GO:0030117 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.1 0.9 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 0.7 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 14.6 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 0.7 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 0.5 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 1.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 1.8 GO:0051233 spindle midzone(GO:0051233)
0.1 0.4 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 10.1 GO:0031902 late endosome membrane(GO:0031902)
0.1 1.6 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 0.8 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 12.8 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 1.9 GO:0005925 focal adhesion(GO:0005925)
0.1 0.8 GO:0032433 filopodium tip(GO:0032433)
0.1 11.3 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.1 0.5 GO:0005642 annulate lamellae(GO:0005642)
0.1 0.5 GO:0042588 zymogen granule(GO:0042588)
0.0 1.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.8 GO:0000974 Prp19 complex(GO:0000974)
0.0 1.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.3 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 7.9 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.3 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 1.0 GO:0035579 specific granule membrane(GO:0035579)
0.0 7.6 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 107.2 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 38.1 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.6 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 2.0 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 3.3 GO:0015030 Cajal body(GO:0015030)
0.0 0.5 GO:0010369 chromocenter(GO:0010369)
0.0 2.9 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.8 GO:0005839 proteasome core complex(GO:0005839)
0.0 1.4 GO:0030666 endocytic vesicle membrane(GO:0030666)
0.0 2.6 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.7 GO:0042555 MCM complex(GO:0042555)
0.0 0.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 3.5 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.2 GO:0005776 autophagosome(GO:0005776)
0.0 1.9 GO:0000786 nucleosome(GO:0000786)
0.0 15.0 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.3 GO:1990393 3M complex(GO:1990393)
0.0 3.8 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 0.9 GO:0070820 tertiary granule(GO:0070820)
0.0 1.4 GO:0031226 intrinsic component of plasma membrane(GO:0031226)
0.0 0.3 GO:0031906 late endosome lumen(GO:0031906)
0.0 1.4 GO:0097546 ciliary base(GO:0097546)
0.0 2.7 GO:0043202 lysosomal lumen(GO:0043202)
0.0 1.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.5 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 1.8 GO:0042175 nuclear outer membrane-endoplasmic reticulum membrane network(GO:0042175)
0.0 2.5 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 1.4 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.6 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.7 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 8.0 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 0.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.4 GO:0030684 preribosome(GO:0030684) small-subunit processome(GO:0032040)
0.0 3.1 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 0.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 1.0 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.9 GO:0005796 Golgi lumen(GO:0005796)
0.0 88.4 GO:0016021 integral component of membrane(GO:0016021)
0.0 0.2 GO:0048500 signal recognition particle(GO:0048500)
0.0 1.2 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.9 GO:0016235 aggresome(GO:0016235)
0.0 1.1 GO:0044454 nuclear chromosome part(GO:0044454)
0.0 1.8 GO:0030133 transport vesicle(GO:0030133)
0.0 1.9 GO:0036064 ciliary basal body(GO:0036064)
0.0 1.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.5 GO:0005819 spindle(GO:0005819)
0.0 1.4 GO:0005923 bicellular tight junction(GO:0005923)
0.0 4.6 GO:0031252 cell leading edge(GO:0031252)
0.0 0.2 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.8 GO:0072686 mitotic spindle(GO:0072686)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.3 13.0 GO:0005136 interleukin-4 receptor binding(GO:0005136)
2.5 10.1 GO:0030107 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
2.2 11.0 GO:0004914 interleukin-5 receptor activity(GO:0004914)
1.8 7.2 GO:0032396 inhibitory MHC class I receptor activity(GO:0032396)
1.8 12.6 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
1.8 7.0 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
1.6 8.0 GO:0019770 IgG receptor activity(GO:0019770)
1.6 19.0 GO:0030369 ICAM-3 receptor activity(GO:0030369)
1.6 4.7 GO:0001851 complement component C3b binding(GO:0001851)
1.5 4.4 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
1.4 10.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
1.4 11.5 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
1.4 10.0 GO:0016019 peptidoglycan receptor activity(GO:0016019)
1.3 5.3 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
1.3 29.6 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
1.3 3.8 GO:0004730 pseudouridylate synthase activity(GO:0004730)
1.3 7.7 GO:0017159 pantetheine hydrolase activity(GO:0017159)
1.2 14.8 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
1.2 3.5 GO:0050405 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
1.1 3.4 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
1.1 20.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
1.0 5.2 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
1.0 14.6 GO:0019864 IgG binding(GO:0019864)
1.0 5.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
1.0 2.9 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.9 15.4 GO:0004875 complement receptor activity(GO:0004875)
0.8 5.0 GO:0004918 interleukin-8 receptor activity(GO:0004918)
0.8 3.2 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.8 22.0 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.8 4.7 GO:0004974 leukotriene receptor activity(GO:0004974)
0.8 12.5 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.7 19.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.7 12.7 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.7 5.0 GO:0004522 ribonuclease A activity(GO:0004522)
0.7 6.8 GO:0005497 androgen binding(GO:0005497)
0.7 6.7 GO:1990405 protein antigen binding(GO:1990405)
0.7 2.0 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.6 6.4 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.6 3.7 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.6 2.4 GO:0047946 glutamine N-acyltransferase activity(GO:0047946)
0.6 23.1 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.6 5.2 GO:0019863 IgE binding(GO:0019863)
0.6 5.7 GO:0030882 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.6 3.4 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.6 2.9 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.6 1.7 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.6 2.8 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.5 1.6 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.5 4.3 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.5 2.1 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.5 2.1 GO:0046921 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.5 4.6 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.5 2.0 GO:0001069 regulatory region RNA binding(GO:0001069)
0.5 1.5 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.5 10.5 GO:0005537 mannose binding(GO:0005537)
0.5 5.9 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.5 6.1 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.5 1.4 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.5 2.8 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.5 1.4 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.4 4.0 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.4 1.8 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.4 1.7 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.4 1.3 GO:0004794 L-threonine ammonia-lyase activity(GO:0004794)
0.4 8.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.4 2.5 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.4 11.6 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.4 12.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.4 3.5 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.4 2.8 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.4 2.9 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.4 2.9 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.4 3.2 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.4 5.3 GO:0019957 C-C chemokine binding(GO:0019957)
0.3 1.7 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.3 1.0 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.3 1.6 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.3 1.3 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.3 3.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.3 1.6 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.3 0.9 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.3 4.6 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.3 2.4 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.3 0.9 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.3 8.5 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.3 1.4 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.3 6.3 GO:0051400 BH domain binding(GO:0051400)
0.3 3.4 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.3 1.9 GO:0004594 pantothenate kinase activity(GO:0004594)
0.3 3.5 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.3 2.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.3 0.8 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.3 0.8 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.3 4.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.3 1.0 GO:0061769 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.2 2.7 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.2 1.0 GO:0009384 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761) N-acylmannosamine kinase activity(GO:0009384)
0.2 1.7 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.2 0.5 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.2 2.7 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.2 0.7 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.2 0.7 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.2 0.9 GO:0070012 oligopeptidase activity(GO:0070012)
0.2 1.9 GO:0043426 MRF binding(GO:0043426)
0.2 4.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.2 3.8 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.2 1.0 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.2 0.6 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.2 2.0 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.2 0.8 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.2 0.8 GO:0003896 DNA primase activity(GO:0003896)
0.2 7.6 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.2 3.5 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.2 4.6 GO:0001784 phosphotyrosine binding(GO:0001784)
0.2 0.7 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.2 2.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.2 10.4 GO:0042287 MHC protein binding(GO:0042287)
0.2 22.5 GO:0030295 protein kinase activator activity(GO:0030295)
0.2 0.7 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.2 2.7 GO:0050786 RAGE receptor binding(GO:0050786)
0.2 1.7 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.2 3.2 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.2 9.0 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 1.9 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.7 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.1 1.6 GO:0050681 androgen receptor binding(GO:0050681)
0.1 4.4 GO:0070403 NAD+ binding(GO:0070403)
0.1 32.0 GO:0003823 antigen binding(GO:0003823)
0.1 2.2 GO:0043422 protein kinase B binding(GO:0043422)
0.1 1.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 1.8 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.5 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.1 2.9 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.1 1.2 GO:0030621 U4 snRNA binding(GO:0030621)
0.1 0.5 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.1 2.9 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.1 1.0 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 0.5 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 0.6 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 5.6 GO:0043394 proteoglycan binding(GO:0043394)
0.1 1.9 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.1 1.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 1.1 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 1.9 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.1 6.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 4.4 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 1.3 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 1.0 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 46.6 GO:0030246 carbohydrate binding(GO:0030246)
0.1 0.6 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.1 1.7 GO:0016208 AMP binding(GO:0016208)
0.1 2.3 GO:0005522 profilin binding(GO:0005522)
0.1 1.2 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.1 0.9 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.6 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 0.5 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 2.9 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 0.6 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.1 2.6 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 4.2 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 1.0 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.1 0.3 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 0.6 GO:0019776 Atg8 ligase activity(GO:0019776)
0.1 2.5 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.1 2.0 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 1.3 GO:0089720 caspase binding(GO:0089720)
0.1 2.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 0.4 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 2.8 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.5 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 5.4 GO:0016279 protein-lysine N-methyltransferase activity(GO:0016279)
0.1 3.8 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 6.6 GO:0019843 rRNA binding(GO:0019843)
0.1 0.5 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 2.3 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 1.4 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 8.5 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 3.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.7 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 1.1 GO:0019215 intermediate filament binding(GO:0019215)
0.1 1.0 GO:0004985 opioid receptor activity(GO:0004985)
0.1 0.9 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.1 2.0 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.3 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.1 0.7 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.3 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.1 1.1 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 3.0 GO:0003785 actin monomer binding(GO:0003785)
0.1 14.9 GO:0005125 cytokine activity(GO:0005125)
0.1 1.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 1.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 3.2 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.1 1.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 1.9 GO:0015278 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.1 1.7 GO:0005123 death receptor binding(GO:0005123)
0.1 1.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 1.9 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 2.1 GO:0005521 lamin binding(GO:0005521)
0.1 1.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 2.0 GO:0017136 NAD-dependent histone deacetylase activity(GO:0017136) histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) NAD-dependent protein deacetylase activity(GO:0034979)
0.1 0.4 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 0.6 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.1 1.8 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 0.2 GO:0016005 phospholipase A2 activator activity(GO:0016005)
0.1 29.0 GO:0005096 GTPase activator activity(GO:0005096)
0.1 2.1 GO:0017166 vinculin binding(GO:0017166)
0.1 1.2 GO:0043295 glutathione binding(GO:0043295)
0.1 0.8 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.1 4.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.7 GO:0000295 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.1 1.0 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 1.3 GO:0008494 translation activator activity(GO:0008494)
0.0 1.2 GO:0010857 calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.0 1.2 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 4.3 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 2.0 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 3.2 GO:0019894 kinesin binding(GO:0019894)
0.0 1.8 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 1.9 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 1.4 GO:0005109 frizzled binding(GO:0005109)
0.0 1.9 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.6 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 1.9 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 1.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 1.2 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.5 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 1.2 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.7 GO:0097602 cullin family protein binding(GO:0097602)
0.0 2.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.1 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 0.3 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 2.6 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 1.3 GO:0070035 ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0 0.2 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.7 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 1.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.9 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.4 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 1.2 GO:0042393 histone binding(GO:0042393)
0.0 0.4 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.6 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.8 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.2 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.5 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 1.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 1.7 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.4 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.4 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 1.3 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 2.6 GO:0008013 beta-catenin binding(GO:0008013)
0.0 2.7 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.2 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 14.0 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.5 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.7 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.5 GO:0008143 poly(A) binding(GO:0008143)
0.0 4.2 GO:0004518 nuclease activity(GO:0004518)
0.0 0.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.7 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.2 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 1.5 GO:1901981 phosphatidylinositol phosphate binding(GO:1901981)
0.0 2.0 GO:0001047 core promoter binding(GO:0001047)
0.0 4.2 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.0 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.0 2.8 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.4 GO:0001099 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0 0.6 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.4 GO:0019902 phosphatase binding(GO:0019902)
0.0 0.5 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0045159 myosin II binding(GO:0045159)
0.0 0.5 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 45.8 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.6 92.5 PID BCR 5PATHWAY BCR signaling pathway
0.6 9.9 PID IL5 PATHWAY IL5-mediated signaling events
0.4 16.1 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.4 12.7 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.3 11.8 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.3 4.4 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.3 30.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.3 10.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.3 3.0 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.2 6.7 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.2 8.3 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.2 11.8 PID EPHA FWDPATHWAY EPHA forward signaling
0.2 10.8 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.2 7.9 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.2 9.2 PID IL2 1PATHWAY IL2-mediated signaling events
0.2 7.1 PID IL1 PATHWAY IL1-mediated signaling events
0.2 5.7 PID IL6 7 PATHWAY IL6-mediated signaling events
0.2 8.8 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.2 19.4 PID RHOA REG PATHWAY Regulation of RhoA activity
0.2 11.0 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 18.3 PID CMYB PATHWAY C-MYB transcription factor network
0.1 5.8 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 2.5 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 5.6 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 10.4 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 4.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 1.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 4.0 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 1.2 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.1 5.9 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.1 2.3 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 3.4 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 0.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 11.6 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 2.4 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.1 2.9 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 2.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 4.3 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 6.2 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 2.7 PID RAS PATHWAY Regulation of Ras family activation
0.1 13.4 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 3.1 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 5.2 PID P53 REGULATION PATHWAY p53 pathway
0.1 1.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 21.9 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 2.4 PID ENDOTHELIN PATHWAY Endothelins
0.0 1.0 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.9 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.1 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.1 PID ATR PATHWAY ATR signaling pathway
0.0 0.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.7 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.1 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.7 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 2.9 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.9 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.0 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.6 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.2 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.7 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
1.1 47.6 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.9 21.8 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.7 13.2 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.7 85.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.7 10.0 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.6 46.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.6 41.3 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.5 7.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.5 29.0 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.4 7.7 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.4 20.4 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.4 7.8 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.3 1.9 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.3 5.0 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.3 6.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.3 11.0 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.2 4.7 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.2 6.7 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.2 4.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.2 16.1 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.2 1.2 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.2 5.5 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.2 1.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.2 4.0 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.2 4.5 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.2 3.3 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.2 4.4 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.2 2.3 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2 7.8 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.2 1.8 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.2 2.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 4.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.2 3.7 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.2 2.7 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.1 5.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 3.8 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 21.5 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 8.3 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 1.8 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.1 34.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 0.9 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 3.4 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 2.9 REACTOME IL 3 5 AND GM CSF SIGNALING Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.1 3.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 25.6 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.1 2.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 2.9 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.9 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 2.2 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1 2.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 7.1 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 1.0 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.1 1.8 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 2.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 2.5 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 1.3 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.1 2.2 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 2.0 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.1 7.2 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 1.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 5.5 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.1 7.1 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 1.8 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 1.6 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.1 4.6 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.7 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 1.3 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 2.5 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 5.0 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.0 5.3 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 3.0 REACTOME SIGNALING BY THE B CELL RECEPTOR BCR Genes involved in Signaling by the B Cell Receptor (BCR)
0.0 1.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.7 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 1.7 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.5 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 1.5 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 1.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 2.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.5 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 1.6 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 2.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.4 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.6 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 1.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.5 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 2.0 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production