Motif ID: SRF

Z-value: 4.862


Transcription factors associated with SRF:

Gene SymbolEntrez IDGene Name
SRF ENSG00000112658.6 SRF

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
SRFhg19_v2_chr6_+_43140095_431401450.799.4e-08Click!


Activity profile for motif SRF.

activity profile for motif SRF


Sorted Z-values histogram for motif SRF

Sorted Z-values for motif SRF



Network of associatons between targets according to the STRING database.



First level regulatory network of SRF

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_45826125 44.486 ENST00000221476.3
CKM
creatine kinase, muscle
chr15_-_35088340 30.337 ENST00000290378.4
ACTC1
actin, alpha, cardiac muscle 1
chr1_-_229569834 25.220 ENST00000366684.3
ENST00000366683.2
ACTA1

actin, alpha 1, skeletal muscle

chr19_+_11650709 23.855 ENST00000586059.1
CNN1
calponin 1, basic, smooth muscle
chr20_+_35169885 18.589 ENST00000279022.2
ENST00000346786.2
MYL9

myosin, light chain 9, regulatory

chr14_-_94443065 18.206 ENST00000555287.1
ASB2
ankyrin repeat and SOCS box containing 2
chr14_-_94443105 17.527 ENST00000555019.1
ASB2
ankyrin repeat and SOCS box containing 2
chr19_-_36247910 15.578 ENST00000587965.1
ENST00000004982.3
HSPB6

heat shock protein, alpha-crystallin-related, B6

chr2_+_74120094 15.373 ENST00000409731.3
ENST00000345517.3
ENST00000409918.1
ENST00000442912.1
ENST00000409624.1
ACTG2




actin, gamma 2, smooth muscle, enteric




chr6_-_123958141 14.835 ENST00000334268.4
TRDN
triadin
chr17_+_33474826 13.186 ENST00000268876.5
ENST00000433649.1
ENST00000378449.1
UNC45B


unc-45 homolog B (C. elegans)


chr2_+_88367299 12.820 ENST00000419482.2
ENST00000444564.2
SMYD1

SET and MYND domain containing 1

chr10_+_88428370 12.671 ENST00000372066.3
ENST00000263066.6
ENST00000372056.4
ENST00000310944.6
ENST00000361373.4
ENST00000542786.1
LDB3





LIM domain binding 3





chr17_+_33474860 12.427 ENST00000394570.2
UNC45B
unc-45 homolog B (C. elegans)
chr3_+_187930491 12.296 ENST00000443217.1
LPP
LIM domain containing preferred translocation partner in lipoma
chr10_-_29923893 12.134 ENST00000355867.4
SVIL
supervillin
chr3_-_52486841 12.009 ENST00000496590.1
TNNC1
troponin C type 1 (slow)
chr6_-_123957942 11.681 ENST00000398178.3
TRDN
triadin
chr6_-_123958051 11.598 ENST00000546248.1
TRDN
triadin
chr9_-_35691017 11.545 ENST00000378292.3
TPM2
tropomyosin 2 (beta)
chr2_+_88367368 11.526 ENST00000438570.1
SMYD1
SET and MYND domain containing 1
chr17_-_41132088 10.943 ENST00000454303.1
ENST00000591916.1
ENST00000451885.2
PTGES3L-AARSD1
PTGES3L

PTGES3L-AARSD1 readthrough
prostaglandin E synthase 3 (cytosolic)-like

chr6_-_105585022 10.482 ENST00000314641.5
BVES
blood vessel epicardial substance
chr6_-_123958111 10.475 ENST00000542443.1
TRDN
triadin
chr14_-_23877474 10.114 ENST00000405093.3
MYH6
myosin, heavy chain 6, cardiac muscle, alpha
chr1_-_208084387 9.791 ENST00000537704.1
CD34
CD34 molecule
chr10_+_88428206 9.743 ENST00000429277.2
ENST00000458213.2
ENST00000352360.5
LDB3


LIM domain binding 3


chr2_-_106015491 9.678 ENST00000408995.1
ENST00000393353.3
ENST00000322142.8
FHL2


four and a half LIM domains 2


chr1_-_208084729 9.640 ENST00000310833.7
ENST00000356522.4
CD34

CD34 molecule

chr17_-_42875115 9.559 ENST00000591137.1
CTC-296K1.4
CTC-296K1.4
chr2_-_106054952 9.469 ENST00000336660.5
ENST00000393352.3
ENST00000607522.1
FHL2


four and a half LIM domains 2


chr2_-_106015527 8.919 ENST00000344213.4
ENST00000358129.4
FHL2

four and a half LIM domains 2

chr7_-_44180884 8.413 ENST00000458240.1
ENST00000223364.3
MYL7

myosin, light chain 7, regulatory

chr18_-_3219847 8.364 ENST00000261606.7
MYOM1
myomesin 1
chr3_+_187930429 8.260 ENST00000420410.1
LPP
LIM domain containing preferred translocation partner in lipoma
chr3_-_46904946 8.060 ENST00000292327.4
MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr3_-_46904918 7.846 ENST00000395869.1
MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr7_-_44180673 7.793 ENST00000457314.1
ENST00000447951.1
ENST00000431007.1
MYL7


myosin, light chain 7, regulatory


chr10_+_123922941 7.698 ENST00000360561.3
TACC2
transforming, acidic coiled-coil containing protein 2
chr18_-_3220106 7.694 ENST00000356443.4
ENST00000400569.3
MYOM1

myomesin 1

chr16_+_30383613 7.622 ENST00000568749.1
MYLPF
myosin light chain, phosphorylatable, fast skeletal muscle
chr9_+_124088860 7.266 ENST00000373806.1
GSN
gelsolin
chr3_-_99594948 7.227 ENST00000471562.1
ENST00000495625.2
FILIP1L

filamin A interacting protein 1-like

chr17_-_27949911 6.977 ENST00000492276.2
ENST00000345068.5
ENST00000584602.1
CORO6


coronin 6


chr3_-_99595037 6.828 ENST00000383694.2
FILIP1L
filamin A interacting protein 1-like
chr2_-_128432639 6.666 ENST00000545738.2
ENST00000355119.4
ENST00000409808.2
LIMS2


LIM and senescent cell antigen-like domains 2


chr1_+_16085263 6.658 ENST00000483633.2
ENST00000502739.1
ENST00000431771.2
FBLIM1


filamin binding LIM protein 1


chr2_-_161056802 6.505 ENST00000283249.2
ENST00000409872.1
ITGB6

integrin, beta 6

chr8_+_1993152 5.595 ENST00000262113.4
MYOM2
myomesin 2
chr8_-_37189432 5.414 ENST00000518765.1
RP11-527N22.1
RP11-527N22.1
chr1_-_11907829 5.251 ENST00000376480.3
NPPA
natriuretic peptide A
chr15_+_96873921 5.221 ENST00000394166.3
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr16_+_66413128 5.133 ENST00000563425.2
CDH5
cadherin 5, type 2 (vascular endothelium)
chr19_+_13135439 4.878 ENST00000586873.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr2_-_161056762 4.801 ENST00000428609.2
ENST00000409967.2
ITGB6

integrin, beta 6

chr10_+_75757863 4.763 ENST00000372755.3
ENST00000211998.4
ENST00000417648.2
VCL


vinculin


chr5_-_33892118 4.634 ENST00000515401.1
ADAMTS12
ADAM metallopeptidase with thrombospondin type 1 motif, 12
chr8_+_1993173 4.590 ENST00000523438.1
MYOM2
myomesin 2
chr7_-_27183263 4.522 ENST00000222726.3
HOXA5
homeobox A5
chrX_-_153602991 4.505 ENST00000369850.3
ENST00000422373.1
FLNA

filamin A, alpha

chr10_-_90712520 4.503 ENST00000224784.6
ACTA2
actin, alpha 2, smooth muscle, aorta
chr19_+_13135386 4.444 ENST00000360105.4
ENST00000588228.1
ENST00000591028.1
NFIX


nuclear factor I/X (CCAAT-binding transcription factor)


chr11_+_117070037 4.443 ENST00000392951.4
ENST00000525531.1
ENST00000278968.6
TAGLN


transgelin


chr5_+_137774706 4.429 ENST00000378339.2
ENST00000254901.5
ENST00000506158.1
REEP2


receptor accessory protein 2


chr5_-_33892204 4.364 ENST00000504830.1
ADAMTS12
ADAM metallopeptidase with thrombospondin type 1 motif, 12
chr5_-_169816638 4.361 ENST00000521859.1
ENST00000274629.4
KCNMB1

potassium large conductance calcium-activated channel, subfamily M, beta member 1

chr10_-_17659357 4.132 ENST00000326961.6
ENST00000361271.3
PTPLA

protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A

chr4_+_87928140 4.040 ENST00000307808.6
AFF1
AF4/FMR2 family, member 1
chr15_+_74218787 3.909 ENST00000261921.7
LOXL1
lysyl oxidase-like 1
chr5_-_58295712 3.903 ENST00000317118.8
PDE4D
phosphodiesterase 4D, cAMP-specific
chr11_+_86667117 3.902 ENST00000531827.1
RP11-736K20.6
RP11-736K20.6
chr11_-_47374246 3.866 ENST00000545968.1
ENST00000399249.2
ENST00000256993.4
MYBPC3


myosin binding protein C, cardiac


chr1_+_16085244 3.865 ENST00000400773.1
FBLIM1
filamin binding LIM protein 1
chr8_-_97398865 3.833 ENST00000523862.1
KB-1448A5.1
KB-1448A5.1
chr22_+_36784632 3.706 ENST00000424761.1
RP4-633O19__A.1
RP4-633O19__A.1
chr5_-_176923846 3.706 ENST00000506537.1
PDLIM7
PDZ and LIM domain 7 (enigma)
chr18_+_61143994 3.648 ENST00000382771.4
SERPINB5
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr7_-_559853 3.588 ENST00000405692.2
PDGFA
platelet-derived growth factor alpha polypeptide
chr7_-_107643567 3.513 ENST00000393559.1
ENST00000439976.1
ENST00000393560.1
LAMB1


laminin, beta 1


chr16_-_3350614 3.450 ENST00000268674.2
TIGD7
tigger transposable element derived 7
chr4_+_186064395 3.434 ENST00000281456.6
SLC25A4
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
chr5_+_66254698 3.434 ENST00000405643.1
ENST00000407621.1
ENST00000432426.1
MAST4


microtubule associated serine/threonine kinase family member 4


chr5_-_176923803 3.426 ENST00000506161.1
PDLIM7
PDZ and LIM domain 7 (enigma)
chr17_+_50939459 3.342 ENST00000412360.1
AC102948.2
Uncharacterized protein
chr4_+_87928353 3.276 ENST00000511722.1
AFF1
AF4/FMR2 family, member 1
chr10_+_31610064 3.260 ENST00000446923.2
ENST00000559476.1
ZEB1

zinc finger E-box binding homeobox 1

chr4_+_87928413 3.231 ENST00000544085.1
AFF1
AF4/FMR2 family, member 1
chr3_+_187930719 3.225 ENST00000312675.4
LPP
LIM domain containing preferred translocation partner in lipoma
chr10_-_17659234 3.186 ENST00000466335.1
PTPLA
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr5_-_33892046 3.137 ENST00000352040.3
ADAMTS12
ADAM metallopeptidase with thrombospondin type 1 motif, 12
chr11_-_65667884 3.093 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOSL1


FOS-like antigen 1


chr5_+_150404904 3.088 ENST00000521632.1
GPX3
glutathione peroxidase 3 (plasma)
chr11_-_2162468 3.058 ENST00000434045.2
IGF2
insulin-like growth factor 2 (somatomedin A)
chr11_-_65667997 3.046 ENST00000312562.2
ENST00000534222.1
FOSL1

FOS-like antigen 1

chr7_-_107643674 3.035 ENST00000222399.6
LAMB1
laminin, beta 1
chr19_+_13134772 2.974 ENST00000587760.1
ENST00000585575.1
NFIX

nuclear factor I/X (CCAAT-binding transcription factor)

chr5_+_96077888 2.943 ENST00000509259.1
ENST00000503828.1
CAST

calpastatin

chr1_+_167599532 2.924 ENST00000537350.1
RCSD1
RCSD domain containing 1
chr22_+_45714672 2.861 ENST00000424557.1
FAM118A
family with sequence similarity 118, member A
chr12_+_52445191 2.808 ENST00000243050.1
ENST00000394825.1
ENST00000550763.1
ENST00000394824.2
ENST00000548232.1
ENST00000562373.1
NR4A1





nuclear receptor subfamily 4, group A, member 1





chr7_+_114055052 2.711 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
FOXP2







forkhead box P2







chr20_+_4702548 2.691 ENST00000305817.2
PRND
prion protein 2 (dublet)
chr6_+_151561085 2.633 ENST00000402676.2
AKAP12
A kinase (PRKA) anchor protein 12
chr16_-_11375179 2.595 ENST00000312511.3
PRM1
protamine 1
chr22_-_36850991 2.533 ENST00000442579.1
RP5-1119A7.14
RP5-1119A7.14
chr7_+_149416439 2.528 ENST00000497895.1
KRBA1
KRAB-A domain containing 1
chr1_+_167599330 2.524 ENST00000367854.3
ENST00000361496.3
RCSD1

RCSD domain containing 1

chr16_+_86229728 2.440 ENST00000601250.1
LINC01082
long intergenic non-protein coding RNA 1082
chr19_+_54372693 2.381 ENST00000391768.2
MYADM
myeloid-associated differentiation marker
chr6_+_151561506 2.364 ENST00000253332.1
AKAP12
A kinase (PRKA) anchor protein 12
chr17_-_10560619 2.324 ENST00000583535.1
MYH3
myosin, heavy chain 3, skeletal muscle, embryonic
chr8_-_22550815 2.294 ENST00000317216.2
EGR3
early growth response 3
chr19_+_54372639 2.293 ENST00000391769.2
MYADM
myeloid-associated differentiation marker
chrX_-_11284095 2.281 ENST00000303025.6
ENST00000534860.1
ARHGAP6

Rho GTPase activating protein 6

chr11_-_2162162 2.259 ENST00000381389.1
IGF2
insulin-like growth factor 2 (somatomedin A)
chr22_-_36357671 2.258 ENST00000408983.2
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr2_+_101179152 2.255 ENST00000264254.6
PDCL3
phosducin-like 3
chr8_-_22550691 2.204 ENST00000519492.1
EGR3
early growth response 3
chr1_+_113263199 2.162 ENST00000361886.3
FAM19A3
family with sequence similarity 19 (chemokine (C-C motif)-like), member A3
chr12_+_54426637 2.047 ENST00000312492.2
HOXC5
homeobox C5
chr16_+_30077055 2.046 ENST00000564595.2
ENST00000569798.1
ALDOA

aldolase A, fructose-bisphosphate

chr9_-_79520989 1.996 ENST00000376713.3
ENST00000376718.3
ENST00000428286.1
PRUNE2


prune homolog 2 (Drosophila)


chr19_+_16177826 1.932 ENST00000589897.1
TPM4
tropomyosin 4
chr19_+_57901208 1.919 ENST00000366197.5
ENST00000596282.1
ENST00000597400.1
ENST00000598895.1
ENST00000336128.7
ENST00000596617.1
ZNF548




AC003002.6
zinc finger protein 548




Uncharacterized protein
chr6_+_43139037 1.909 ENST00000265354.4
SRF
serum response factor (c-fos serum response element-binding transcription factor)
chr1_-_168106536 1.900 ENST00000537209.1
ENST00000361697.2
ENST00000546300.1
ENST00000367835.1
GPR161



G protein-coupled receptor 161



chr2_+_87769459 1.894 ENST00000414030.1
ENST00000437561.1
LINC00152

long intergenic non-protein coding RNA 152

chr16_+_30077098 1.884 ENST00000395240.3
ENST00000566846.1
ALDOA

aldolase A, fructose-bisphosphate

chr7_-_94285511 1.869 ENST00000265735.7
SGCE
sarcoglycan, epsilon
chr7_-_94285472 1.860 ENST00000437425.2
ENST00000447873.1
ENST00000415788.2
SGCE


sarcoglycan, epsilon


chr7_-_94285402 1.805 ENST00000428696.2
ENST00000445866.2
SGCE

sarcoglycan, epsilon

chr19_+_35861831 1.743 ENST00000454971.1
GPR42
G protein-coupled receptor 42 (gene/pseudogene)
chr17_-_41132410 1.725 ENST00000409399.1
ENST00000421990.2
ENST00000409446.3
ENST00000453594.1
PTGES3L-AARSD1

PTGES3L

PTGES3L-AARSD1 readthrough

prostaglandin E synthase 3 (cytosolic)-like

chr12_+_4382917 1.647 ENST00000261254.3
CCND2
cyclin D2
chr19_+_45971246 1.568 ENST00000585836.1
ENST00000417353.2
ENST00000353609.3
ENST00000591858.1
ENST00000443841.2
ENST00000590335.1
FOSB





FBJ murine osteosarcoma viral oncogene homolog B





chr1_+_113263041 1.527 ENST00000369630.3
FAM19A3
family with sequence similarity 19 (chemokine (C-C motif)-like), member A3
chr1_-_89591749 1.435 ENST00000370466.3
GBP2
guanylate binding protein 2, interferon-inducible
chr1_+_223889310 1.358 ENST00000434648.1
CAPN2
calpain 2, (m/II) large subunit
chr5_+_40679584 1.290 ENST00000302472.3
PTGER4
prostaglandin E receptor 4 (subtype EP4)
chr22_+_38004723 1.284 ENST00000381756.5
GGA1
golgi-associated, gamma adaptin ear containing, ARF binding protein 1
chr3_-_123339418 1.274 ENST00000583087.1
MYLK
myosin light chain kinase
chr15_+_83776324 1.244 ENST00000379390.6
ENST00000379386.4
ENST00000565774.1
ENST00000565982.1
TM6SF1



transmembrane 6 superfamily member 1



chr4_+_189321881 1.208 ENST00000512839.1
ENST00000513313.1
LINC01060

long intergenic non-protein coding RNA 1060

chr1_+_206858328 1.207 ENST00000367103.3
MAPKAPK2
mitogen-activated protein kinase-activated protein kinase 2
chr22_+_45714301 1.169 ENST00000427777.1
FAM118A
family with sequence similarity 118, member A
chr19_+_1026298 1.134 ENST00000263097.4
CNN2
calponin 2
chr19_+_54372877 1.113 ENST00000414489.1
MYADM
myeloid-associated differentiation marker
chr15_+_33603147 1.101 ENST00000415757.3
ENST00000389232.4
RYR3

ryanodine receptor 3

chr3_-_71294304 1.097 ENST00000498215.1
FOXP1
forkhead box P1
chr2_-_139259244 1.075 ENST00000414911.1
ENST00000431985.1
AC097721.2

AC097721.2

chr10_-_16859361 1.042 ENST00000377921.3
RSU1
Ras suppressor protein 1
chr9_+_92219919 0.998 ENST00000252506.6
ENST00000375769.1
GADD45G

growth arrest and DNA-damage-inducible, gamma

chr7_+_107531580 0.990 ENST00000537148.1
ENST00000440410.1
ENST00000437604.2
DLD


dihydrolipoamide dehydrogenase


chr3_-_157221380 0.990 ENST00000468233.1
VEPH1
ventricular zone expressed PH domain-containing 1
chr14_+_105266933 0.966 ENST00000555360.1
ZBTB42
zinc finger and BTB domain containing 42
chr12_-_125398850 0.917 ENST00000535859.1
ENST00000546271.1
ENST00000540700.1
ENST00000546120.1
UBC



ubiquitin C



chr10_-_16859442 0.908 ENST00000602389.1
ENST00000345264.5
RSU1

Ras suppressor protein 1

chr3_-_9834463 0.874 ENST00000439043.1
TADA3
transcriptional adaptor 3
chr3_-_157221357 0.864 ENST00000494677.1
VEPH1
ventricular zone expressed PH domain-containing 1
chr22_+_38004832 0.857 ENST00000405147.3
ENST00000429218.1
ENST00000325180.8
ENST00000337437.4
GGA1



golgi-associated, gamma adaptin ear containing, ARF binding protein 1



chr18_-_54318353 0.844 ENST00000590954.1
ENST00000540155.1
TXNL1

thioredoxin-like 1

chr2_-_96811170 0.843 ENST00000288943.4
DUSP2
dual specificity phosphatase 2
chr13_+_27825706 0.798 ENST00000272274.4
ENST00000319826.4
ENST00000326092.4
RPL21


ribosomal protein L21


chr5_-_142000883 0.770 ENST00000359370.6
FGF1
fibroblast growth factor 1 (acidic)
chr3_-_123339343 0.719 ENST00000578202.1
MYLK
myosin light chain kinase
chr17_+_42634844 0.698 ENST00000315323.3
FZD2
frizzled family receptor 2
chr14_+_22992573 0.660 ENST00000390516.1
TRAJ21
T cell receptor alpha joining 21
chr5_-_124080203 0.651 ENST00000504926.1
ZNF608
zinc finger protein 608
chr19_+_1026566 0.647 ENST00000348419.3
ENST00000565096.2
ENST00000562958.2
ENST00000562075.2
ENST00000607102.1
CNN2




calponin 2




chr2_-_208031943 0.581 ENST00000421199.1
ENST00000457962.1
KLF7

Kruppel-like factor 7 (ubiquitous)

chr19_+_52102540 0.558 ENST00000601315.1
AC018755.17
AC018755.17
chr2_-_161264385 0.515 ENST00000409972.1
RBMS1
RNA binding motif, single stranded interacting protein 1
chr2_+_56179262 0.474 ENST00000606639.1
RP11-481J13.1
RP11-481J13.1
chr22_+_38004473 0.438 ENST00000414350.3
ENST00000343632.4
GGA1

golgi-associated, gamma adaptin ear containing, ARF binding protein 1

chr14_+_74034310 0.421 ENST00000538782.1
ACOT2
acyl-CoA thioesterase 2
chr13_+_42614176 0.383 ENST00000540693.1
DGKH
diacylglycerol kinase, eta
chr12_-_50616122 0.379 ENST00000552823.1
ENST00000552909.1
LIMA1

LIM domain and actin binding 1

chr2_+_191792376 0.340 ENST00000409428.1
ENST00000409215.1
GLS

glutaminase

chr2_-_231989808 0.337 ENST00000258400.3
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr7_+_143078379 0.329 ENST00000449630.1
ENST00000457235.1
ZYX

zyxin

chr1_+_11994715 0.323 ENST00000449038.1
ENST00000376369.3
ENST00000429000.2
ENST00000196061.4
PLOD1



procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1



chr19_+_16178317 0.311 ENST00000344824.6
ENST00000538887.1
TPM4

tropomyosin 4

chr22_+_45714361 0.301 ENST00000452238.1
FAM118A
family with sequence similarity 118, member A
chr17_-_55911970 0.299 ENST00000581805.1
ENST00000580960.1
RP11-60A24.3

RP11-60A24.3

chr17_-_46671323 0.299 ENST00000239151.5
HOXB5
homeobox B5
chr2_+_26915584 0.284 ENST00000302909.3
KCNK3
potassium channel, subfamily K, member 3
chr17_+_73452695 0.275 ENST00000582186.1
ENST00000582455.1
ENST00000581252.1
ENST00000579208.1
KIAA0195



KIAA0195



chr3_-_9834375 0.262 ENST00000343450.2
ENST00000301964.2
TADA3

transcriptional adaptor 3

chr22_-_36784035 0.239 ENST00000216181.5
MYH9
myosin, heavy chain 9, non-muscle
chr17_-_4890649 0.233 ENST00000361571.5
CAMTA2
calmodulin binding transcription activator 2
chr22_-_50216853 0.228 ENST00000342989.5
ENST00000542442.1
BRD1

bromodomain containing 1

chrX_-_103499602 0.211 ENST00000372588.4
ESX1
ESX homeobox 1
chr4_-_10118469 0.207 ENST00000499869.2
WDR1
WD repeat domain 1
chr7_+_112120908 0.187 ENST00000439068.2
ENST00000312849.4
ENST00000429049.1
LSMEM1


leucine-rich single-pass membrane protein 1


chr12_-_50616382 0.165 ENST00000552783.1
LIMA1
LIM domain and actin binding 1
chr11_-_71823715 0.163 ENST00000545944.1
ENST00000502597.2
ANAPC15

anaphase promoting complex subunit 15

chrX_-_101694853 0.146 ENST00000372749.1
NXF2B
nuclear RNA export factor 2B
chr17_-_4890919 0.128 ENST00000572543.1
ENST00000381311.5
ENST00000348066.3
ENST00000358183.4
CAMTA2



calmodulin binding transcription activator 2



chr11_+_59807748 0.126 ENST00000278855.2
ENST00000532905.1
PLAC1L

oocyte secreted protein 2

chr8_+_97597148 0.089 ENST00000521590.1
SDC2
syndecan 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
6.3 25.2 GO:0043501 skeletal muscle adaptation(GO:0043501)
3.2 15.9 GO:1903115 regulation of muscle filament sliding(GO:0032971) regulation of actin filament-based movement(GO:1903115)
3.0 30.3 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
2.6 44.5 GO:0006600 creatine metabolic process(GO:0006600)
2.0 10.1 GO:0048739 cardiac muscle fiber development(GO:0048739)
1.5 6.1 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
1.5 4.5 GO:0060435 bronchiole development(GO:0060435) intestinal epithelial cell maturation(GO:0060574) intestinal epithelial cell development(GO:0060576)
1.5 4.5 GO:0051764 actin crosslink formation(GO:0051764)
1.3 5.2 GO:0060838 radial pattern formation(GO:0009956) lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
1.1 3.4 GO:0060547 negative regulation of necrotic cell death(GO:0060547)
0.8 15.2 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.8 27.5 GO:0043462 regulation of ATPase activity(GO:0043462)
0.8 3.1 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.6 3.6 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.5 5.1 GO:2000114 blood vessel maturation(GO:0001955) regulation of establishment of cell polarity(GO:2000114)
0.5 59.9 GO:0006937 regulation of muscle contraction(GO:0006937)
0.5 5.0 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.5 5.3 GO:0046628 positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.5 2.7 GO:0060013 righting reflex(GO:0060013)
0.4 1.8 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.4 7.3 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.4 121.7 GO:0006936 muscle contraction(GO:0006936)
0.4 5.3 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.3 6.5 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.3 2.3 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889) negative regulation of adherens junction organization(GO:1903392)
0.3 28.1 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.2 0.7 GO:0090047 obsolete positive regulation of transcription regulator activity(GO:0090047)
0.2 20.9 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.2 4.3 GO:0007520 myoblast fusion(GO:0007520)
0.2 24.3 GO:0006338 chromatin remodeling(GO:0006338)
0.2 40.1 GO:0007517 muscle organ development(GO:0007517)
0.2 1.0 GO:0009106 lipoate metabolic process(GO:0009106)
0.1 7.1 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.1 3.6 GO:0060512 prostate gland morphogenesis(GO:0060512)
0.1 3.4 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.1 0.4 GO:0014888 striated muscle adaptation(GO:0014888)
0.1 0.3 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 11.3 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.1 1.6 GO:1904031 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.1 2.6 GO:0030261 chromosome condensation(GO:0030261)
0.1 0.3 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.1 0.8 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.1 4.4 GO:0051592 response to calcium ion(GO:0051592)
0.1 19.4 GO:0050900 leukocyte migration(GO:0050900)
0.1 7.0 GO:0008360 regulation of cell shape(GO:0008360)
0.0 8.5 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.0 0.1 GO:0031000 response to caffeine(GO:0031000)
0.0 0.5 GO:0031529 ruffle organization(GO:0031529)
0.0 2.0 GO:0051318 G1 phase(GO:0051318)
0.0 0.4 GO:0001706 endoderm formation(GO:0001706)
0.0 0.8 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0 2.8 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015) inositol lipid-mediated signaling(GO:0048017)
0.0 9.8 GO:0006260 DNA replication(GO:0006260)
0.0 0.4 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 2.3 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 4.6 GO:0030036 actin cytoskeleton organization(GO:0030036)
0.0 0.6 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.2 GO:0060669 embryonic placenta morphogenesis(GO:0060669) labyrinthine layer morphogenesis(GO:0060713)
0.0 0.9 GO:0032480 negative regulation of type I interferon production(GO:0032480)
0.0 0.3 GO:0009067 aspartate family amino acid biosynthetic process(GO:0009067)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 19.9 GO:0005863 striated muscle myosin thick filament(GO:0005863)
2.2 6.5 GO:0043257 laminin-8 complex(GO:0043257)
2.1 60.2 GO:0031672 A band(GO:0031672)
1.7 36.3 GO:0005859 muscle myosin complex(GO:0005859)
1.4 22.4 GO:0031143 pseudopodium(GO:0031143)
1.3 48.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
1.2 12.1 GO:0071437 invadopodium(GO:0071437)
1.1 12.5 GO:0032982 myosin filament(GO:0032982)
1.1 51.0 GO:0036379 myofilament(GO:0036379)
0.8 5.3 GO:0042629 mast cell granule(GO:0042629)
0.6 44.9 GO:0042641 actomyosin(GO:0042641)
0.6 5.5 GO:0016012 sarcoglycan complex(GO:0016012)
0.3 1.0 GO:0045252 acrosomal matrix(GO:0043159) oxoglutarate dehydrogenase complex(GO:0045252)
0.3 3.9 GO:1903561 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.2 10.5 GO:0016328 lateral plasma membrane(GO:0016328)
0.2 14.1 GO:0016459 myosin complex(GO:0016459)
0.2 11.3 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.1 41.0 GO:0005925 focal adhesion(GO:0005925)
0.1 6.1 GO:0042734 presynaptic membrane(GO:0042734)
0.1 12.2 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 1.1 GO:0030914 STAGA complex(GO:0030914)
0.0 3.6 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 2.6 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 9.5 GO:0005938 cell cortex(GO:0005938)
0.0 2.6 GO:0000786 nucleosome(GO:0000786)
0.0 1.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 5.1 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.7 GO:0032589 neuron projection membrane(GO:0032589)
0.0 2.2 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.0 15.6 GO:0031012 extracellular matrix(GO:0031012)
0.0 3.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.3 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 3.4 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 30.8 GO:0005856 cytoskeleton(GO:0005856)
0.0 3.5 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 2.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.9 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.9 GO:0030666 endocytic vesicle membrane(GO:0030666)
0.0 0.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
6.4 44.5 GO:0004111 creatine kinase activity(GO:0004111)
3.9 19.4 GO:0043199 sulfate binding(GO:0043199)
3.2 15.9 GO:0032038 myosin II heavy chain binding(GO:0032038)
1.7 10.1 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
1.5 4.5 GO:0034987 immunoglobulin receptor binding(GO:0034987) Fc-gamma receptor I complex binding(GO:0034988)
1.3 3.9 GO:0032036 myosin heavy chain binding(GO:0032036)
1.2 50.6 GO:0017022 myosin binding(GO:0017022)
1.1 3.4 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ATP:ADP antiporter activity(GO:0005471) ADP transmembrane transporter activity(GO:0015217)
1.1 12.0 GO:0031013 troponin I binding(GO:0031013)
0.8 18.8 GO:0000146 microfilament motor activity(GO:0000146)
0.6 5.1 GO:0044325 ion channel binding(GO:0044325)
0.6 5.0 GO:0008179 adenylate cyclase binding(GO:0008179)
0.6 4.8 GO:0002162 dystroglycan binding(GO:0002162)
0.6 66.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.6 15.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.5 5.3 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.4 1.9 GO:0010736 serum response element binding(GO:0010736)
0.4 28.1 GO:0050681 androgen receptor binding(GO:0050681)
0.3 3.9 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.3 2.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.3 2.9 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.2 2.3 GO:0016004 phospholipase activator activity(GO:0016004)
0.2 3.6 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 3.9 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.2 3.1 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.2 1.3 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 5.2 GO:0001972 retinoic acid binding(GO:0001972)
0.1 4.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 0.8 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 1.1 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.1 5.3 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 29.9 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 15.1 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 1.1 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 9.7 GO:0051015 actin filament binding(GO:0051015)
0.1 11.3 GO:0005178 integrin binding(GO:0005178)
0.1 0.3 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1 3.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 14.8 GO:0005516 calmodulin binding(GO:0005516)
0.1 1.0 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.1 9.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.3 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.8 GO:0044548 S100 protein binding(GO:0044548)
0.0 16.6 GO:0016563 obsolete transcription activator activity(GO:0016563)
0.0 5.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.4 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 6.9 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 46.7 GO:0005102 receptor binding(GO:0005102)
0.0 3.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.8 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.1 ST_P38_MAPK_PATHWAY p38 MAPK Pathway
0.0 1.0 ST_JNK_MAPK_PATHWAY JNK MAPK Pathway
0.0 1.6 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton