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Illumina Body Map 2: averaged replicates

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Results for STAT6

Z-value: 1.08

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Transcription factors associated with STAT6

Gene Symbol Gene ID Gene Info
STAT6
ENSG00000166888.6 signal transducer and activator of transcription 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
STAT6hg19_v2_chr12_-_57504975_575050190.134.7e-01Click!

Activity profile of STAT6 motif

Sorted Z-values of STAT6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_160616804 2.95 ENST00000538290.1
SLAMF1
signaling lymphocytic activation molecule family member 1
chr14_+_22520762 2.45 ENST00000390449.3
TRAV21
T cell receptor alpha variable 21
chr14_-_25078864 2.08 ENST00000216338.4
ENST00000557220.2
ENST00000382548.4
GZMH
granzyme H (cathepsin G-like 2, protein h-CCPX)
chr5_+_147258266 2.03 ENST00000296694.4
SCGB3A2
secretoglobin, family 3A, member 2
chr7_-_38339890 1.99 ENST00000390341.2
TRGV10
T cell receptor gamma variable 10 (non-functional)
chr17_+_34538310 1.83 ENST00000444414.1
ENST00000378350.4
ENST00000389068.5
ENST00000588929.1
ENST00000589079.1
ENST00000589336.1
ENST00000400702.4
ENST00000591167.1
ENST00000586598.1
ENST00000591637.1
ENST00000378352.4
ENST00000358756.5
CCL4L1
chemokine (C-C motif) ligand 4-like 1
chr12_-_55367361 1.83 ENST00000532804.1
ENST00000531122.1
ENST00000533446.1
TESPA1
thymocyte expressed, positive selection associated 1
chr6_+_31540056 1.79 ENST00000418386.2
LTA
lymphotoxin alpha
chr11_-_118083600 1.75 ENST00000524477.1
AMICA1
adhesion molecule, interacts with CXADR antigen 1
chr17_+_34640031 1.67 ENST00000339270.6
ENST00000482104.1
CCL4L2
chemokine (C-C motif) ligand 4-like 2
chr17_+_34431212 1.67 ENST00000394495.1
CCL4
chemokine (C-C motif) ligand 4
chr1_-_203198790 1.60 ENST00000367229.1
ENST00000255427.3
ENST00000535569.1
CHIT1
chitinase 1 (chitotriosidase)
chr19_-_7764960 1.55 ENST00000593418.1
FCER2
Fc fragment of IgE, low affinity II, receptor for (CD23)
chr12_-_55367331 1.53 ENST00000526532.1
ENST00000532757.1
TESPA1
thymocyte expressed, positive selection associated 1
chr17_+_34639793 1.49 ENST00000394465.2
ENST00000394463.2
ENST00000378342.4
CCL4L2
chemokine (C-C motif) ligand 4-like 2
chr5_+_118691706 1.47 ENST00000415806.2
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr17_-_8770956 1.46 ENST00000311434.9
PIK3R6
phosphoinositide-3-kinase, regulatory subunit 6
chr6_-_24877490 1.44 ENST00000540914.1
ENST00000378023.4
FAM65B
family with sequence similarity 65, member B
chr2_+_191792376 1.44 ENST00000409428.1
ENST00000409215.1
GLS
glutaminase
chr14_-_25103388 1.43 ENST00000526004.1
ENST00000415355.3
GZMB
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr14_-_25103472 1.39 ENST00000216341.4
ENST00000382542.1
ENST00000382540.1
GZMB
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
chr19_-_7766991 1.38 ENST00000597921.1
ENST00000346664.5
FCER2
Fc fragment of IgE, low affinity II, receptor for (CD23)
chr2_+_219745020 1.32 ENST00000258411.3
WNT10A
wingless-type MMTV integration site family, member 10A
chr6_-_41168920 1.26 ENST00000483722.1
TREML2
triggering receptor expressed on myeloid cells-like 2
chr14_+_22386325 1.19 ENST00000390439.2
TRAV13-2
T cell receptor alpha variable 13-2
chr11_-_58980342 1.16 ENST00000361050.3
MPEG1
macrophage expressed 1
chr19_-_54604083 1.04 ENST00000391761.1
ENST00000356532.3
ENST00000359649.4
ENST00000358375.4
ENST00000391760.1
ENST00000351806.4
OSCAR
osteoclast associated, immunoglobulin-like receptor
chr11_+_118175132 1.03 ENST00000361763.4
CD3E
CD3e molecule, epsilon (CD3-TCR complex)
chr16_-_29757272 1.02 ENST00000329410.3
C16orf54
chromosome 16 open reading frame 54
chr19_+_38924316 1.01 ENST00000355481.4
ENST00000360985.3
ENST00000359596.3
RYR1
ryanodine receptor 1 (skeletal)
chr6_-_41254403 1.00 ENST00000589614.1
ENST00000334475.6
ENST00000591620.1
ENST00000244709.4
TREM1
triggering receptor expressed on myeloid cells 1
chr12_+_9144626 0.99 ENST00000543895.1
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr18_-_24445664 0.98 ENST00000578776.1
AQP4
aquaporin 4
chr19_-_52254050 0.94 ENST00000600815.1
FPR1
formyl peptide receptor 1
chr1_+_12123414 0.89 ENST00000263932.2
TNFRSF8
tumor necrosis factor receptor superfamily, member 8
chr5_-_88119580 0.86 ENST00000539796.1
MEF2C
myocyte enhancer factor 2C
chr6_+_138188351 0.84 ENST00000421450.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr18_-_67615088 0.82 ENST00000582621.1
CD226
CD226 molecule
chr10_-_134121438 0.81 ENST00000298630.3
STK32C
serine/threonine kinase 32C
chr3_+_121311966 0.80 ENST00000338040.4
FBXO40
F-box protein 40
chr11_-_128457446 0.79 ENST00000392668.4
ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
chr2_-_175462456 0.78 ENST00000409891.1
ENST00000410117.1
WIPF1
WAS/WASL interacting protein family, member 1
chr7_-_38305279 0.78 ENST00000443402.2
TRGC1
T cell receptor gamma constant 1
chr1_+_12123463 0.77 ENST00000417814.2
TNFRSF8
tumor necrosis factor receptor superfamily, member 8
chr1_+_149754227 0.76 ENST00000444948.1
ENST00000369168.4
FCGR1A
Fc fragment of IgG, high affinity Ia, receptor (CD64)
chr2_+_68961934 0.75 ENST00000409202.3
ARHGAP25
Rho GTPase activating protein 25
chr17_-_34207295 0.73 ENST00000463941.1
ENST00000293272.3
CCL5
chemokine (C-C motif) ligand 5
chr2_+_68961905 0.72 ENST00000295381.3
ARHGAP25
Rho GTPase activating protein 25
chr15_+_77308152 0.72 ENST00000559859.1
PSTPIP1
proline-serine-threonine phosphatase interacting protein 1
chr12_-_111358372 0.71 ENST00000548438.1
ENST00000228841.8
MYL2
myosin, light chain 2, regulatory, cardiac, slow
chr9_-_135996537 0.71 ENST00000372050.3
ENST00000372047.3
RALGDS
ral guanine nucleotide dissociation stimulator
chr7_+_80254279 0.71 ENST00000436384.1
CD36
CD36 molecule (thrombospondin receptor)
chr1_-_120935894 0.71 ENST00000369383.4
ENST00000369384.4
FCGR1B
Fc fragment of IgG, high affinity Ib, receptor (CD64)
chr11_+_65082289 0.70 ENST00000279249.2
CDC42EP2
CDC42 effector protein (Rho GTPase binding) 2
chr21_-_35340759 0.70 ENST00000607953.1
AP000569.9
AP000569.9
chr2_+_68962014 0.70 ENST00000467265.1
ARHGAP25
Rho GTPase activating protein 25
chr8_+_49984894 0.69 ENST00000522267.1
ENST00000399653.4
ENST00000303202.8
C8orf22
chromosome 8 open reading frame 22
chr6_+_147527103 0.69 ENST00000179882.6
STXBP5
syntaxin binding protein 5 (tomosyn)
chr14_-_23285011 0.63 ENST00000397532.3
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr12_-_54779511 0.63 ENST00000551109.1
ENST00000546970.1
ZNF385A
zinc finger protein 385A
chr13_+_50589390 0.62 ENST00000360473.4
ENST00000312942.1
KCNRG
potassium channel regulator
chr1_-_36020531 0.61 ENST00000440579.1
ENST00000494948.1
KIAA0319L
KIAA0319-like
chr6_+_116850174 0.58 ENST00000416171.2
ENST00000368597.2
ENST00000452373.1
ENST00000405399.1
FAM26D
family with sequence similarity 26, member D
chr4_-_48116540 0.58 ENST00000506073.1
TXK
TXK tyrosine kinase
chr6_-_32821599 0.58 ENST00000354258.4
TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr18_+_66382428 0.56 ENST00000578970.1
ENST00000582371.1
ENST00000584775.1
CCDC102B
coiled-coil domain containing 102B
chr5_-_88120083 0.56 ENST00000509373.1
MEF2C
myocyte enhancer factor 2C
chr3_+_140981456 0.55 ENST00000504264.1
ACPL2
acid phosphatase-like 2
chr5_+_36608280 0.55 ENST00000513646.1
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr2_-_109605663 0.55 ENST00000409271.1
ENST00000258443.2
ENST00000376651.1
EDAR
ectodysplasin A receptor
chr22_-_42342692 0.54 ENST00000404067.1
ENST00000402338.1
CENPM
centromere protein M
chr12_-_46663734 0.54 ENST00000550173.1
SLC38A1
solute carrier family 38, member 1
chr2_-_26700900 0.53 ENST00000338581.6
ENST00000339598.3
ENST00000402415.3
OTOF
otoferlin
chr11_-_60719213 0.53 ENST00000227880.3
SLC15A3
solute carrier family 15 (oligopeptide transporter), member 3
chrX_+_135251835 0.53 ENST00000456445.1
FHL1
four and a half LIM domains 1
chr5_+_126984710 0.51 ENST00000379445.3
CTXN3
cortexin 3
chr1_+_114472481 0.51 ENST00000369555.2
HIPK1
homeodomain interacting protein kinase 1
chr14_-_23285069 0.51 ENST00000554758.1
ENST00000397528.4
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr22_-_42343117 0.50 ENST00000407253.3
ENST00000215980.5
CENPM
centromere protein M
chr5_-_88120151 0.50 ENST00000506716.1
MEF2C
myocyte enhancer factor 2C
chr18_-_24445729 0.50 ENST00000383168.4
AQP4
aquaporin 4
chr18_-_53068782 0.49 ENST00000569012.1
TCF4
transcription factor 4
chr3_+_10312604 0.49 ENST00000426850.1
TATDN2
TatD DNase domain containing 2
chr2_-_197226875 0.48 ENST00000409111.1
HECW2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr4_+_144312659 0.48 ENST00000509992.1
GAB1
GRB2-associated binding protein 1
chrX_+_135252050 0.48 ENST00000449474.1
ENST00000345434.3
FHL1
four and a half LIM domains 1
chr1_-_116383738 0.47 ENST00000320238.3
NHLH2
nescient helix loop helix 2
chr22_+_44464923 0.47 ENST00000404989.1
PARVB
parvin, beta
chrX_+_102192200 0.46 ENST00000218249.5
RAB40AL
RAB40A, member RAS oncogene family-like
chr2_-_16804320 0.45 ENST00000355549.2
FAM49A
family with sequence similarity 49, member A
chr12_+_51619860 0.44 ENST00000599633.1
AC139768.1
Uncharacterized protein
chr16_+_30076052 0.44 ENST00000563987.1
ALDOA
aldolase A, fructose-bisphosphate
chr6_+_138188378 0.43 ENST00000420009.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr3_-_10149907 0.43 ENST00000450660.2
ENST00000524279.1
FANCD2OS
FANCD2 opposite strand
chr20_-_23066953 0.42 ENST00000246006.4
CD93
CD93 molecule
chr14_+_61449076 0.41 ENST00000526105.1
SLC38A6
solute carrier family 38, member 6
chr2_-_134326009 0.41 ENST00000409261.1
ENST00000409213.1
NCKAP5
NCK-associated protein 5
chr7_+_10000640 0.41 ENST00000451755.1
AC006373.1
AC006373.1
chrX_+_135251783 0.40 ENST00000394153.2
FHL1
four and a half LIM domains 1
chr2_-_203735976 0.40 ENST00000435143.1
ICA1L
islet cell autoantigen 1,69kDa-like
chr6_+_32821924 0.40 ENST00000374859.2
ENST00000453265.2
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr7_+_76091775 0.39 ENST00000442516.1
DTX2
deltex homolog 2 (Drosophila)
chr12_-_42878101 0.39 ENST00000552108.1
PRICKLE1
prickle homolog 1 (Drosophila)
chr5_+_93954358 0.38 ENST00000504099.1
ANKRD32
ankyrin repeat domain 32
chr12_-_118490217 0.38 ENST00000542304.1
WSB2
WD repeat and SOCS box containing 2
chr16_+_30075783 0.38 ENST00000412304.2
ALDOA
aldolase A, fructose-bisphosphate
chr15_+_89402148 0.38 ENST00000560601.1
ACAN
aggrecan
chrX_+_36254051 0.37 ENST00000378657.4
CXorf30
chromosome X open reading frame 30
chr15_+_91643173 0.37 ENST00000545111.2
SV2B
synaptic vesicle glycoprotein 2B
chr3_-_49851313 0.36 ENST00000333486.3
UBA7
ubiquitin-like modifier activating enzyme 7
chr1_+_66796401 0.36 ENST00000528771.1
PDE4B
phosphodiesterase 4B, cAMP-specific
chr10_+_98064085 0.36 ENST00000419175.1
ENST00000371174.2
DNTT
DNA nucleotidylexotransferase
chr15_+_91643442 0.35 ENST00000394232.1
SV2B
synaptic vesicle glycoprotein 2B
chr12_-_42877764 0.35 ENST00000455697.1
PRICKLE1
prickle homolog 1 (Drosophila)
chr5_+_35856951 0.35 ENST00000303115.3
ENST00000343305.4
ENST00000506850.1
ENST00000511982.1
IL7R
interleukin 7 receptor
chr14_-_24732738 0.34 ENST00000558074.1
ENST00000560226.1
TGM1
transglutaminase 1
chr11_-_77531752 0.34 ENST00000440064.2
ENST00000528095.1
RSF1
remodeling and spacing factor 1
chr8_+_123793633 0.33 ENST00000314393.4
ZHX2
zinc fingers and homeoboxes 2
chr2_-_203735484 0.33 ENST00000420558.1
ENST00000418208.1
ICA1L
islet cell autoantigen 1,69kDa-like
chr6_-_33754778 0.32 ENST00000508327.1
ENST00000513701.1
LEMD2
LEM domain containing 2
chr3_+_130162328 0.32 ENST00000512482.1
COL6A5
collagen, type VI, alpha 5
chr1_-_45965525 0.32 ENST00000488405.2
ENST00000490551.3
ENST00000432082.1
CCDC163P
coiled-coil domain containing 163, pseudogene
chr16_+_57728701 0.32 ENST00000569375.1
ENST00000360716.3
ENST00000569167.1
ENST00000394337.4
ENST00000563126.1
ENST00000336825.8
CCDC135
coiled-coil domain containing 135
chr14_+_61449197 0.31 ENST00000533744.2
SLC38A6
solute carrier family 38, member 6
chr11_-_72463421 0.31 ENST00000393609.3
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr5_-_74162739 0.31 ENST00000513277.1
FAM169A
family with sequence similarity 169, member A
chr9_-_10612703 0.31 ENST00000463477.1
PTPRD
protein tyrosine phosphatase, receptor type, D
chr15_+_27111510 0.31 ENST00000335625.5
GABRA5
gamma-aminobutyric acid (GABA) A receptor, alpha 5
chr11_+_73358594 0.30 ENST00000227214.6
ENST00000398494.4
ENST00000543085.1
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr2_+_197504278 0.30 ENST00000272831.7
ENST00000389175.4
ENST00000472405.2
ENST00000423093.2
CCDC150
coiled-coil domain containing 150
chr7_+_129015484 0.30 ENST00000490911.1
AHCYL2
adenosylhomocysteinase-like 2
chr3_-_179692042 0.30 ENST00000468741.1
PEX5L
peroxisomal biogenesis factor 5-like
chr4_-_120988229 0.29 ENST00000296509.6
MAD2L1
MAD2 mitotic arrest deficient-like 1 (yeast)
chr3_+_63898275 0.29 ENST00000538065.1
ATXN7
ataxin 7
chr11_-_132813627 0.29 ENST00000374778.4
OPCML
opioid binding protein/cell adhesion molecule-like
chr7_+_129015671 0.28 ENST00000466993.1
AHCYL2
adenosylhomocysteinase-like 2
chr11_-_60720002 0.28 ENST00000538739.1
SLC15A3
solute carrier family 15 (oligopeptide transporter), member 3
chr1_+_114472222 0.27 ENST00000369558.1
ENST00000369561.4
HIPK1
homeodomain interacting protein kinase 1
chr17_+_28268623 0.27 ENST00000394835.3
ENST00000320856.5
ENST00000394832.2
ENST00000378738.3
EFCAB5
EF-hand calcium binding domain 5
chr6_+_26440700 0.27 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
BTN3A3
butyrophilin, subfamily 3, member A3
chr3_-_57233966 0.26 ENST00000473921.1
ENST00000295934.3
HESX1
HESX homeobox 1
chr8_+_107593198 0.26 ENST00000517686.1
OXR1
oxidation resistance 1
chr5_+_71475449 0.26 ENST00000504492.1
MAP1B
microtubule-associated protein 1B
chr11_+_118230287 0.26 ENST00000252108.3
ENST00000431736.2
UBE4A
ubiquitination factor E4A
chr15_+_101402041 0.26 ENST00000558475.1
ENST00000558641.1
ENST00000559673.1
RP11-66B24.1
RP11-66B24.1
chr9_-_3469181 0.25 ENST00000366116.2
AL365202.1
Uncharacterized protein
chr15_+_30918879 0.25 ENST00000428041.2
ARHGAP11B
Rho GTPase activating protein 11B
chr3_+_189507432 0.25 ENST00000354600.5
TP63
tumor protein p63
chr3_+_141121164 0.25 ENST00000510338.1
ENST00000504673.1
ZBTB38
zinc finger and BTB domain containing 38
chr8_+_11666649 0.25 ENST00000528643.1
ENST00000525777.1
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr12_-_118490403 0.25 ENST00000535496.1
WSB2
WD repeat and SOCS box containing 2
chr2_-_230786619 0.25 ENST00000389045.3
ENST00000409677.1
TRIP12
thyroid hormone receptor interactor 12
chr2_-_202316169 0.25 ENST00000430254.1
TRAK2
trafficking protein, kinesin binding 2
chr16_+_30075463 0.24 ENST00000562168.1
ENST00000569545.1
ALDOA
aldolase A, fructose-bisphosphate
chr6_-_30524951 0.24 ENST00000376621.3
GNL1
guanine nucleotide binding protein-like 1
chr4_+_54966198 0.24 ENST00000326902.2
ENST00000503800.1
GSX2
GS homeobox 2
chr12_-_42877726 0.24 ENST00000548696.1
PRICKLE1
prickle homolog 1 (Drosophila)
chr2_-_203735586 0.24 ENST00000454326.1
ENST00000432273.1
ENST00000450143.1
ENST00000411681.1
ICA1L
islet cell autoantigen 1,69kDa-like
chr12_+_56435637 0.24 ENST00000356464.5
ENST00000552361.1
RPS26
ribosomal protein S26
chr4_+_141677577 0.24 ENST00000609937.1
RP11-102N12.3
RP11-102N12.3
chr12_-_53097247 0.24 ENST00000341809.3
ENST00000537195.1
KRT77
keratin 77
chr20_+_58251716 0.24 ENST00000355648.4
PHACTR3
phosphatase and actin regulator 3
chr6_-_27880174 0.23 ENST00000303324.2
OR2B2
olfactory receptor, family 2, subfamily B, member 2
chr5_+_110427983 0.23 ENST00000513710.2
ENST00000505303.1
WDR36
WD repeat domain 36
chr4_+_71337834 0.23 ENST00000304887.5
MUC7
mucin 7, secreted
chr2_-_31440377 0.23 ENST00000444918.2
ENST00000403897.3
CAPN14
calpain 14
chr11_-_8964580 0.23 ENST00000325884.1
ASCL3
achaete-scute family bHLH transcription factor 3
chr1_-_153321301 0.23 ENST00000368739.3
PGLYRP4
peptidoglycan recognition protein 4
chr5_+_102201687 0.23 ENST00000304400.7
PAM
peptidylglycine alpha-amidating monooxygenase
chr22_-_42342733 0.21 ENST00000402420.1
CENPM
centromere protein M
chr11_-_77531858 0.21 ENST00000360355.2
RSF1
remodeling and spacing factor 1
chr18_-_44775554 0.21 ENST00000425639.1
ENST00000400404.1
SKOR2
SKI family transcriptional corepressor 2
chr16_-_67694597 0.20 ENST00000393919.4
ENST00000219251.8
ACD
adrenocortical dysplasia homolog (mouse)
chr5_+_102201722 0.20 ENST00000274392.9
ENST00000455264.2
PAM
peptidylglycine alpha-amidating monooxygenase
chr1_+_109256067 0.20 ENST00000271311.2
FNDC7
fibronectin type III domain containing 7
chr6_+_38690622 0.19 ENST00000327475.6
DNAH8
dynein, axonemal, heavy chain 8
chr13_-_74708372 0.19 ENST00000377666.4
KLF12
Kruppel-like factor 12
chr16_+_67694849 0.18 ENST00000602551.1
ENST00000458121.2
ENST00000219255.3
PARD6A
par-6 family cell polarity regulator alpha
chr2_+_145425534 0.18 ENST00000432608.1
ENST00000597655.1
ENST00000598659.1
ENST00000600679.1
ENST00000601277.1
ENST00000451027.1
ENST00000445791.1
ENST00000596540.1
ENST00000596230.1
ENST00000594471.1
ENST00000598248.1
ENST00000597469.1
ENST00000431734.1
ENST00000595686.1
TEX41
testis expressed 41 (non-protein coding)
chr5_+_138609441 0.18 ENST00000509990.1
ENST00000506147.1
ENST00000512107.1
MATR3
matrin 3
chr16_+_30075595 0.18 ENST00000563060.2
ALDOA
aldolase A, fructose-bisphosphate
chr20_+_42136308 0.18 ENST00000434666.1
ENST00000427442.2
ENST00000439769.1
ENST00000418998.1
L3MBTL1
l(3)mbt-like 1 (Drosophila)
chr11_+_65101225 0.17 ENST00000528416.1
ENST00000415073.2
ENST00000252268.4
DPF2
D4, zinc and double PHD fingers family 2
chr14_+_59100774 0.17 ENST00000556859.1
ENST00000421793.1
DACT1
dishevelled-binding antagonist of beta-catenin 1
chr3_+_189507523 0.17 ENST00000437221.1
ENST00000392463.2
ENST00000392461.3
ENST00000449992.1
ENST00000456148.1
TP63
tumor protein p63
chr17_+_44588877 0.17 ENST00000576629.1
LRRC37A2
leucine rich repeat containing 37, member A2
chr14_+_56127960 0.17 ENST00000553624.1
KTN1
kinectin 1 (kinesin receptor)
chr20_+_42574317 0.17 ENST00000358131.5
TOX2
TOX high mobility group box family member 2
chr1_-_241799232 0.17 ENST00000366553.1
CHML
choroideremia-like (Rab escort protein 2)
chr1_+_34632484 0.16 ENST00000373374.3
C1orf94
chromosome 1 open reading frame 94
chr2_+_21444025 0.16 ENST00000435237.1
ENST00000457901.1
AC067959.1
AC067959.1
chr2_+_27440229 0.14 ENST00000264705.4
ENST00000403525.1
CAD
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr2_+_113885138 0.14 ENST00000409930.3
IL1RN
interleukin 1 receptor antagonist
chr6_+_30951487 0.14 ENST00000486149.2
ENST00000376296.3
MUC21
mucin 21, cell surface associated
chr6_+_84222220 0.13 ENST00000369700.3
PRSS35
protease, serine, 35
chr1_+_109265033 0.13 ENST00000445274.1
FNDC7
fibronectin type III domain containing 7
chr9_-_111619239 0.13 ENST00000374667.3
ACTL7B
actin-like 7B
chr11_-_77532050 0.13 ENST00000308488.6
RSF1
remodeling and spacing factor 1
chr8_-_117886732 0.13 ENST00000517485.1
RAD21
RAD21 homolog (S. pombe)
chr14_+_56127989 0.13 ENST00000555573.1
KTN1
kinectin 1 (kinesin receptor)

Network of associatons between targets according to the STRING database.

First level regulatory network of STAT6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.2 GO:2000349 negative regulation of CD40 signaling pathway(GO:2000349)
0.8 4.7 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.6 1.7 GO:0045556 TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556)
0.5 3.4 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.4 2.8 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.3 2.4 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.3 1.9 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.2 1.6 GO:0044245 polysaccharide digestion(GO:0044245)
0.2 1.0 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.2 1.4 GO:0006543 glutamine catabolic process(GO:0006543)
0.2 1.0 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892) regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.2 1.0 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.1 0.6 GO:0046967 cytosol to ER transport(GO:0046967)
0.1 0.7 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 0.8 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.1 1.1 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.1 0.3 GO:0098972 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.1 0.8 GO:1904996 PML body organization(GO:0030578) positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.1 0.6 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 0.5 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.1 0.6 GO:1902164 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.1 1.3 GO:0048733 sebaceous gland development(GO:0048733)
0.1 0.2 GO:0051714 positive regulation of cytolysis in other organism(GO:0051714)
0.1 1.0 GO:0071313 cellular response to caffeine(GO:0071313)
0.1 0.6 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.4 GO:0018032 protein amidation(GO:0018032)
0.1 0.2 GO:0060380 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381)
0.1 1.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.8 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.1 0.7 GO:0072564 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1 0.2 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.1 0.7 GO:0031017 exocrine pancreas development(GO:0031017)
0.1 0.7 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.3 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.1 0.3 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 0.9 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.1 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.0 0.5 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.0 0.7 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.2 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.0 0.3 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.3 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 1.5 GO:0006833 water transport(GO:0006833)
0.0 2.1 GO:0019835 cytolysis(GO:0019835)
0.0 0.4 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.6 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.0 0.5 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 1.3 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.3 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.4 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.3 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.3 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0 0.3 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.0 0.2 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.0 0.3 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 1.0 GO:0042269 regulation of natural killer cell mediated cytotoxicity(GO:0042269)
0.0 0.2 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.0 0.4 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.3 GO:0008038 neuron recognition(GO:0008038)
0.0 1.4 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.1 GO:0048691 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.0 0.1 GO:0050925 negative regulation of negative chemotaxis(GO:0050925) apoptotic process involved in luteolysis(GO:0061364)
0.0 1.4 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 1.9 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.0 0.1 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.2 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.0 0.3 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 0.1 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.3 GO:0061339 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0 0.0 GO:1901963 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901963) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.0 1.0 GO:0006968 cellular defense response(GO:0006968)
0.0 0.5 GO:0001504 neurotransmitter uptake(GO:0001504)
0.0 0.5 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.1 GO:0036079 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.2 1.0 GO:1990425 ryanodine receptor complex(GO:1990425)
0.2 0.7 GO:0031213 RSF complex(GO:0031213)
0.1 0.6 GO:0042825 TAP complex(GO:0042825)
0.1 1.0 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.2 GO:0097679 other organism cytoplasm(GO:0097679)
0.1 2.0 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 3.4 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.4 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 3.9 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 2.8 GO:0001772 immunological synapse(GO:0001772)
0.0 0.7 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.7 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.8 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 3.7 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.2 GO:0000798 nuclear cohesin complex(GO:0000798)
0.0 1.5 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 1.6 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 1.4 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.2 GO:0070187 telosome(GO:0070187)
0.0 5.0 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.3 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 1.6 GO:0001669 acrosomal vesicle(GO:0001669)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.4 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.3 2.9 GO:0019863 IgE binding(GO:0019863)
0.3 1.0 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.2 1.4 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.8 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.1 1.7 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.9 GO:0005124 N-formyl peptide receptor activity(GO:0004982) scavenger receptor binding(GO:0005124)
0.1 1.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.7 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.1 0.7 GO:0001515 opioid peptide activity(GO:0001515)
0.1 1.6 GO:0004568 chitinase activity(GO:0004568)
0.1 0.3 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.1 1.5 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.6 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.6 GO:0046979 TAP2 binding(GO:0046979)
0.1 1.5 GO:0015250 water channel activity(GO:0015250)
0.1 0.4 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 1.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.7 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 1.0 GO:0042608 T cell receptor binding(GO:0042608)
0.1 1.9 GO:0035198 miRNA binding(GO:0035198)
0.1 0.8 GO:0019864 IgG binding(GO:0019864)
0.1 0.3 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 0.2 GO:0032093 SAM domain binding(GO:0032093)
0.1 0.2 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.1 0.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 1.1 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.1 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.0 0.4 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.2 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.4 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.1 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 1.4 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.7 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.8 GO:0005522 profilin binding(GO:0005522)
0.0 1.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.5 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.0 0.3 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.5 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 1.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 1.3 GO:0005109 frizzled binding(GO:0005109)
0.0 0.5 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.6 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 2.3 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.3 GO:0031702 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.0 0.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.2 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0036080 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.5 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 4.5 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.7 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 1.3 PID CD40 PATHWAY CD40/CD40L signaling
0.0 2.7 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 1.7 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.0 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.8 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.5 PID EPO PATHWAY EPO signaling pathway
0.0 1.8 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 6.5 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.3 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 2.8 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 1.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.0 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 1.9 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.7 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 2.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 3.0 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.7 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 1.3 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 3.2 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.0 1.5 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 2.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.5 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.2 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 1.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.7 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere