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Illumina Body Map 2: averaged replicates

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Results for TBX21_TBR1

Z-value: 1.52

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Transcription factors associated with TBX21_TBR1

Gene Symbol Gene ID Gene Info
TBX21
ENSG00000073861.2 T-box transcription factor 21
TBR1
ENSG00000136535.10 T-box brain transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX21hg19_v2_chr17_+_45810594_458106100.383.0e-02Click!
TBR1hg19_v2_chr2_+_162272605_162272753-0.038.7e-01Click!

Activity profile of TBX21_TBR1 motif

Sorted Z-values of TBX21_TBR1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_1993173 4.88 ENST00000523438.1
MYOM2
myomesin 2
chr14_-_23876801 4.53 ENST00000356287.3
MYH6
myosin, heavy chain 6, cardiac muscle, alpha
chr2_-_219031709 4.16 ENST00000295683.2
CXCR1
chemokine (C-X-C motif) receptor 1
chr21_+_30503282 3.95 ENST00000399925.1
MAP3K7CL
MAP3K7 C-terminal like
chr11_+_112832202 3.58 ENST00000534015.1
NCAM1
neural cell adhesion molecule 1
chr22_+_18593097 3.26 ENST00000426208.1
TUBA8
tubulin, alpha 8
chr21_+_30502806 3.21 ENST00000399928.1
ENST00000399926.1
MAP3K7CL
MAP3K7 C-terminal like
chr10_-_75226166 3.05 ENST00000544628.1
PPP3CB
protein phosphatase 3, catalytic subunit, beta isozyme
chr5_+_54320078 2.99 ENST00000231009.2
GZMK
granzyme K (granzyme 3; tryptase II)
chr9_-_71161505 2.93 ENST00000446290.1
RP11-274B18.2
RP11-274B18.2
chr7_+_143013198 2.85 ENST00000343257.2
CLCN1
chloride channel, voltage-sensitive 1
chr11_+_112832090 2.81 ENST00000533760.1
NCAM1
neural cell adhesion molecule 1
chr3_+_42190714 2.74 ENST00000449246.1
TRAK1
trafficking protein, kinesin binding 1
chr11_+_112832133 2.68 ENST00000524665.1
NCAM1
neural cell adhesion molecule 1
chr2_+_219247021 2.68 ENST00000539932.1
SLC11A1
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
chrY_+_2709527 2.43 ENST00000250784.8
RPS4Y1
ribosomal protein S4, Y-linked 1
chr7_-_36764004 2.34 ENST00000431169.1
AOAH
acyloxyacyl hydrolase (neutrophil)
chr6_-_130536774 2.32 ENST00000532763.1
SAMD3
sterile alpha motif domain containing 3
chr7_-_36764062 2.16 ENST00000435386.1
AOAH
acyloxyacyl hydrolase (neutrophil)
chrY_+_2709906 2.15 ENST00000430575.1
RPS4Y1
ribosomal protein S4, Y-linked 1
chr7_-_36764142 2.07 ENST00000258749.5
ENST00000535891.1
AOAH
acyloxyacyl hydrolase (neutrophil)
chr17_-_42452063 2.00 ENST00000588098.1
ITGA2B
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
chr11_+_122709200 1.98 ENST00000227348.4
CRTAM
cytotoxic and regulatory T cell molecule
chr22_-_31688431 1.98 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chr11_+_64073699 1.97 ENST00000405666.1
ENST00000468670.1
ESRRA
estrogen-related receptor alpha
chr7_+_110731062 1.96 ENST00000308478.5
ENST00000451085.1
ENST00000422987.3
ENST00000421101.1
LRRN3
leucine rich repeat neuronal 3
chrX_-_19689106 1.91 ENST00000379716.1
SH3KBP1
SH3-domain kinase binding protein 1
chr22_-_31688381 1.90 ENST00000487265.2
PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chr11_+_61447845 1.84 ENST00000257215.5
DAGLA
diacylglycerol lipase, alpha
chr7_-_142240014 1.83 ENST00000390363.2
TRBV9
T cell receptor beta variable 9
chr2_-_40679186 1.82 ENST00000406785.2
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr1_-_11907829 1.81 ENST00000376480.3
NPPA
natriuretic peptide A
chr22_+_40441456 1.81 ENST00000402203.1
TNRC6B
trinucleotide repeat containing 6B
chr1_-_25256368 1.77 ENST00000308873.6
RUNX3
runt-related transcription factor 3
chr6_-_160166218 1.71 ENST00000537657.1
SOD2
superoxide dismutase 2, mitochondrial
chr1_-_154167124 1.70 ENST00000515609.1
TPM3
tropomyosin 3
chr5_-_39270725 1.68 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYB
FYN binding protein
chr7_+_80253387 1.68 ENST00000438020.1
CD36
CD36 molecule (thrombospondin receptor)
chr1_+_202995611 1.67 ENST00000367240.2
PPFIA4
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
chr17_-_43502987 1.58 ENST00000376922.2
ARHGAP27
Rho GTPase activating protein 27
chr10_-_126432821 1.58 ENST00000280780.6
FAM53B
family with sequence similarity 53, member B
chr1_-_36947652 1.55 ENST00000533491.1
CSF3R
colony stimulating factor 3 receptor (granulocyte)
chr14_+_77582905 1.55 ENST00000557408.1
TMEM63C
transmembrane protein 63C
chrX_+_47050798 1.53 ENST00000412206.1
ENST00000427561.1
UBA1
ubiquitin-like modifier activating enzyme 1
chr12_+_69742121 1.53 ENST00000261267.2
ENST00000549690.1
ENST00000548839.1
LYZ
lysozyme
chr12_-_90024360 1.50 ENST00000393164.2
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr1_-_205290865 1.48 ENST00000367157.3
NUAK2
NUAK family, SNF1-like kinase, 2
chr15_-_38852251 1.47 ENST00000558432.1
RASGRP1
RAS guanyl releasing protein 1 (calcium and DAG-regulated)
chr12_-_89746264 1.47 ENST00000548755.1
DUSP6
dual specificity phosphatase 6
chr12_-_89746173 1.44 ENST00000308385.6
DUSP6
dual specificity phosphatase 6
chr1_+_172628154 1.42 ENST00000340030.3
ENST00000367721.2
FASLG
Fas ligand (TNF superfamily, member 6)
chr17_-_72619783 1.42 ENST00000328630.3
CD300E
CD300e molecule
chr12_+_58148842 1.39 ENST00000266643.5
MARCH9
membrane-associated ring finger (C3HC4) 9
chr5_-_131132658 1.37 ENST00000514667.1
ENST00000511848.1
ENST00000510461.1
CTC-432M15.3
FNIP1
Folliculin-interacting protein 1
folliculin interacting protein 1
chr8_+_1993152 1.36 ENST00000262113.4
MYOM2
myomesin 2
chr3_-_66551351 1.36 ENST00000273261.3
LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr6_+_167536230 1.35 ENST00000341935.5
ENST00000349984.4
CCR6
chemokine (C-C motif) receptor 6
chr10_+_135050908 1.34 ENST00000325980.9
VENTX
VENT homeobox
chr1_-_156786530 1.33 ENST00000368198.3
SH2D2A
SH2 domain containing 2A
chr22_+_40342819 1.33 ENST00000407075.3
GRAP2
GRB2-related adaptor protein 2
chr1_-_156786634 1.32 ENST00000392306.2
ENST00000368199.3
SH2D2A
SH2 domain containing 2A
chrX_+_109245863 1.30 ENST00000372072.3
TMEM164
transmembrane protein 164
chr3_-_66551397 1.28 ENST00000383703.3
LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr7_-_142120321 1.25 ENST00000390377.1
TRBV7-7
T cell receptor beta variable 7-7
chr8_-_101724989 1.23 ENST00000517403.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr10_-_76868931 1.22 ENST00000372700.3
ENST00000473072.2
ENST00000491677.2
ENST00000607131.1
ENST00000372702.3
DUSP13
dual specificity phosphatase 13
chr4_-_90757364 1.20 ENST00000508895.1
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr11_+_73358690 1.19 ENST00000545798.1
ENST00000539157.1
ENST00000546251.1
ENST00000535582.1
ENST00000538227.1
ENST00000543524.1
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr12_+_65672702 1.19 ENST00000538045.1
ENST00000535239.1
MSRB3
methionine sulfoxide reductase B3
chr11_+_59824060 1.18 ENST00000395032.2
ENST00000358152.2
MS4A3
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr17_-_72619869 1.17 ENST00000392619.1
ENST00000426295.2
CD300E
CD300e molecule
chr7_+_123241908 1.16 ENST00000434204.1
ENST00000437535.1
ENST00000451215.1
ASB15
ankyrin repeat and SOCS box containing 15
chr11_+_64950801 1.14 ENST00000526468.1
CAPN1
calpain 1, (mu/I) large subunit
chr5_+_150040403 1.14 ENST00000517768.1
ENST00000297130.4
MYOZ3
myozenin 3
chrX_+_123480375 1.14 ENST00000360027.4
SH2D1A
SH2 domain containing 1A
chrX_+_123480421 1.12 ENST00000477673.2
SH2D1A
SH2 domain containing 1A
chr11_-_133826852 1.10 ENST00000533871.2
ENST00000321016.8
IGSF9B
immunoglobulin superfamily, member 9B
chrX_+_123480194 1.10 ENST00000371139.4
SH2D1A
SH2 domain containing 1A
chr16_+_27413483 1.10 ENST00000337929.3
ENST00000564089.1
IL21R
interleukin 21 receptor
chr4_+_160188889 1.10 ENST00000264431.4
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr8_-_66754172 1.09 ENST00000401827.3
PDE7A
phosphodiesterase 7A
chr2_+_219246746 1.09 ENST00000233202.6
SLC11A1
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
chr12_-_111180644 1.09 ENST00000551676.1
ENST00000550991.1
ENST00000335007.5
ENST00000340766.5
PPP1CC
protein phosphatase 1, catalytic subunit, gamma isozyme
chr7_-_44179972 1.08 ENST00000446581.1
MYL7
myosin, light chain 7, regulatory
chr8_-_143833918 1.08 ENST00000359228.3
LYPD2
LY6/PLAUR domain containing 2
chr10_+_45406627 1.08 ENST00000389583.4
TMEM72
transmembrane protein 72
chr17_-_9929581 1.06 ENST00000437099.2
ENST00000396115.2
GAS7
growth arrest-specific 7
chr5_-_74807418 1.06 ENST00000405807.4
ENST00000261415.7
COL4A3BP
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
chr2_+_87808725 1.06 ENST00000413202.1
LINC00152
long intergenic non-protein coding RNA 152
chr3_+_101498269 1.06 ENST00000491511.2
NXPE3
neurexophilin and PC-esterase domain family, member 3
chr3_+_50654821 1.05 ENST00000457064.1
MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
chr12_+_10183271 1.03 ENST00000355819.1
CLEC9A
C-type lectin domain family 9, member A
chr15_+_40861487 1.03 ENST00000315616.7
ENST00000559271.1
RPUSD2
RNA pseudouridylate synthase domain containing 2
chr6_-_13487825 1.03 ENST00000603223.1
GFOD1
glucose-fructose oxidoreductase domain containing 1
chr17_+_34538310 1.02 ENST00000444414.1
ENST00000378350.4
ENST00000389068.5
ENST00000588929.1
ENST00000589079.1
ENST00000589336.1
ENST00000400702.4
ENST00000591167.1
ENST00000586598.1
ENST00000591637.1
ENST00000378352.4
ENST00000358756.5
CCL4L1
chemokine (C-C motif) ligand 4-like 1
chr15_+_41913690 1.02 ENST00000563576.1
MGA
MGA, MAX dimerization protein
chr1_-_158300747 1.02 ENST00000451207.1
CD1B
CD1b molecule
chr5_-_49737184 1.01 ENST00000508934.1
ENST00000303221.5
EMB
embigin
chr13_+_76378305 1.01 ENST00000526371.1
ENST00000526528.1
LMO7
LIM domain 7
chr1_+_203256898 1.00 ENST00000433008.1
RP11-134P9.3
RP11-134P9.3
chr1_-_11024258 0.98 ENST00000418570.2
C1orf127
chromosome 1 open reading frame 127
chr11_+_59824127 0.97 ENST00000278865.3
MS4A3
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr9_+_34990219 0.97 ENST00000541010.1
ENST00000454002.2
ENST00000545841.1
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr4_-_90756769 0.96 ENST00000345009.4
ENST00000505199.1
ENST00000502987.1
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr14_-_62217779 0.96 ENST00000554254.1
HIF1A-AS2
HIF1A antisense RNA 2
chr10_-_23003460 0.96 ENST00000376573.4
PIP4K2A
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr1_+_40840320 0.96 ENST00000372708.1
SMAP2
small ArfGAP2
chr14_+_98602380 0.95 ENST00000557072.1
RP11-61O1.2
RP11-61O1.2
chr1_+_154975110 0.95 ENST00000535420.1
ENST00000368426.3
ZBTB7B
zinc finger and BTB domain containing 7B
chr16_+_50313426 0.95 ENST00000569265.1
ADCY7
adenylate cyclase 7
chr17_-_47308128 0.95 ENST00000413580.1
ENST00000511066.1
PHOSPHO1
phosphatase, orphan 1
chr2_+_201994042 0.94 ENST00000417748.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr1_+_202172848 0.94 ENST00000255432.7
LGR6
leucine-rich repeat containing G protein-coupled receptor 6
chr17_-_36884451 0.94 ENST00000595377.1
AC006449.1
NS5ATP13TP1; Uncharacterized protein
chr21_-_31864275 0.93 ENST00000334063.4
KRTAP19-3
keratin associated protein 19-3
chr11_+_73358594 0.93 ENST00000227214.6
ENST00000398494.4
ENST00000543085.1
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr12_+_66582919 0.93 ENST00000545837.1
ENST00000457197.2
IRAK3
interleukin-1 receptor-associated kinase 3
chr1_+_184356188 0.92 ENST00000235307.6
C1orf21
chromosome 1 open reading frame 21
chr12_-_68553512 0.92 ENST00000229135.3
IFNG
interferon, gamma
chr19_+_12862604 0.92 ENST00000553030.1
BEST2
bestrophin 2
chr2_-_113594279 0.92 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
IL1B
interleukin 1, beta
chr12_+_14572070 0.92 ENST00000545769.1
ENST00000428217.2
ENST00000396279.2
ENST00000542514.1
ENST00000536279.1
ATF7IP
activating transcription factor 7 interacting protein
chr13_-_30160925 0.91 ENST00000450494.1
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr1_+_76540386 0.91 ENST00000328299.3
ST6GALNAC3
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr10_-_65028938 0.91 ENST00000402544.1
JMJD1C
jumonji domain containing 1C
chr11_+_71846764 0.91 ENST00000456237.1
ENST00000442948.2
ENST00000546166.1
FOLR3
folate receptor 3 (gamma)
chr6_+_45390222 0.90 ENST00000359524.5
RUNX2
runt-related transcription factor 2
chr13_+_42031679 0.89 ENST00000379359.3
RGCC
regulator of cell cycle
chr14_+_22433675 0.89 ENST00000390442.3
TRAV12-3
T cell receptor alpha variable 12-3
chr20_+_58630972 0.89 ENST00000313426.1
C20orf197
chromosome 20 open reading frame 197
chr19_+_55235969 0.88 ENST00000402254.2
ENST00000538269.1
ENST00000541392.1
ENST00000291860.1
ENST00000396284.2
KIR3DL1
KIR3DL3
KIR2DL4
killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3
killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
chr16_+_6069072 0.87 ENST00000547605.1
ENST00000550418.1
ENST00000553186.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr4_-_5991545 0.86 ENST00000531445.1
C4orf50
chromosome 4 open reading frame 50
chr12_+_11905413 0.86 ENST00000545027.1
ETV6
ets variant 6
chr7_+_77469439 0.85 ENST00000450574.1
ENST00000416283.2
ENST00000248550.7
PHTF2
putative homeodomain transcription factor 2
chr7_+_31726822 0.84 ENST00000409146.3
PPP1R17
protein phosphatase 1, regulatory subunit 17
chr7_+_107110488 0.84 ENST00000304402.4
GPR22
G protein-coupled receptor 22
chr11_-_33913708 0.84 ENST00000257818.2
LMO2
LIM domain only 2 (rhombotin-like 1)
chr7_+_142012967 0.84 ENST00000390357.3
TRBV4-1
T cell receptor beta variable 4-1
chr10_-_76868866 0.83 ENST00000607487.1
DUSP13
dual specificity phosphatase 13
chr4_+_108746282 0.83 ENST00000503862.1
SGMS2
sphingomyelin synthase 2
chr1_+_32716857 0.82 ENST00000482949.1
ENST00000495610.2
LCK
lymphocyte-specific protein tyrosine kinase
chr1_+_20915409 0.82 ENST00000375071.3
CDA
cytidine deaminase
chr3_-_44465475 0.81 ENST00000416124.1
LINC00694
long intergenic non-protein coding RNA 694
chr13_+_32634993 0.81 ENST00000436046.1
FRY
furry homolog (Drosophila)
chr16_+_30386098 0.80 ENST00000322861.7
MYLPF
myosin light chain, phosphorylatable, fast skeletal muscle
chr5_-_88180342 0.80 ENST00000502983.1
MEF2C
myocyte enhancer factor 2C
chr2_+_120687335 0.80 ENST00000544261.1
PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr7_+_150264365 0.80 ENST00000255945.2
ENST00000461940.1
GIMAP4
GTPase, IMAP family member 4
chr4_-_8073554 0.79 ENST00000510277.1
ABLIM2
actin binding LIM protein family, member 2
chr3_+_107243204 0.79 ENST00000456817.1
ENST00000458458.1
BBX
bobby sox homolog (Drosophila)
chr17_-_76713100 0.79 ENST00000585509.1
CYTH1
cytohesin 1
chr4_+_154622652 0.79 ENST00000260010.6
TLR2
toll-like receptor 2
chr1_+_158325684 0.79 ENST00000368162.2
CD1E
CD1e molecule
chr2_-_25391507 0.79 ENST00000380794.1
POMC
proopiomelanocortin
chr11_+_107799118 0.78 ENST00000320578.2
RAB39A
RAB39A, member RAS oncogene family
chr10_-_16563870 0.78 ENST00000298943.3
C1QL3
complement component 1, q subcomponent-like 3
chr14_+_75746664 0.78 ENST00000557139.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr7_-_142224280 0.77 ENST00000390367.3
TRBV11-1
T cell receptor beta variable 11-1
chr1_+_32716840 0.77 ENST00000336890.5
LCK
lymphocyte-specific protein tyrosine kinase
chr6_-_13487784 0.77 ENST00000379287.3
GFOD1
glucose-fructose oxidoreductase domain containing 1
chr1_-_36020531 0.77 ENST00000440579.1
ENST00000494948.1
KIAA0319L
KIAA0319-like
chr2_+_29001711 0.76 ENST00000418910.1
PPP1CB
protein phosphatase 1, catalytic subunit, beta isozyme
chr7_+_150264470 0.76 ENST00000479232.1
GIMAP4
GTPase, IMAP family member 4
chr10_+_118305435 0.76 ENST00000369221.2
PNLIP
pancreatic lipase
chr7_+_107220660 0.76 ENST00000465919.1
ENST00000445771.2
ENST00000479917.1
ENST00000421217.1
ENST00000457837.1
BCAP29
B-cell receptor-associated protein 29
chr12_-_91348949 0.75 ENST00000358859.2
CCER1
coiled-coil glutamate-rich protein 1
chr17_+_75084717 0.75 ENST00000561721.2
ENST00000589827.1
ENST00000392476.2
SEC14L1
SEC14-like 1 (S. cerevisiae)
chr6_-_6225026 0.75 ENST00000445223.1
F13A1
coagulation factor XIII, A1 polypeptide
chr6_+_45389893 0.74 ENST00000371432.3
RUNX2
runt-related transcription factor 2
chr5_+_94727048 0.74 ENST00000283357.5
FAM81B
family with sequence similarity 81, member B
chr17_-_38721711 0.73 ENST00000578085.1
ENST00000246657.2
CCR7
chemokine (C-C motif) receptor 7
chr1_-_11042094 0.73 ENST00000377004.4
ENST00000377008.4
C1orf127
chromosome 1 open reading frame 127
chr1_+_174843548 0.72 ENST00000478442.1
ENST00000465412.1
RABGAP1L
RAB GTPase activating protein 1-like
chr19_-_51875894 0.72 ENST00000600427.1
ENST00000595217.1
ENST00000221978.5
NKG7
natural killer cell group 7 sequence
chr12_-_76879852 0.72 ENST00000548341.1
OSBPL8
oxysterol binding protein-like 8
chr12_-_52685312 0.71 ENST00000327741.5
KRT81
keratin 81
chr6_-_31619697 0.71 ENST00000434444.1
BAG6
BCL2-associated athanogene 6
chr17_-_1553346 0.71 ENST00000301336.6
RILP
Rab interacting lysosomal protein
chr1_+_39456895 0.71 ENST00000432648.3
ENST00000446189.2
ENST00000372984.4
AKIRIN1
akirin 1
chr12_-_51740463 0.71 ENST00000293636.1
CELA1
chymotrypsin-like elastase family, member 1
chr10_+_94451574 0.71 ENST00000492654.2
HHEX
hematopoietically expressed homeobox
chr17_+_34431212 0.71 ENST00000394495.1
CCL4
chemokine (C-C motif) ligand 4
chr16_+_57702099 0.70 ENST00000333493.4
ENST00000327655.6
GPR97
G protein-coupled receptor 97
chr11_-_85779971 0.69 ENST00000393346.3
PICALM
phosphatidylinositol binding clathrin assembly protein
chr5_+_95998070 0.69 ENST00000421689.2
ENST00000510756.1
ENST00000512620.1
CAST
calpastatin
chr1_+_10057274 0.69 ENST00000294435.7
RBP7
retinol binding protein 7, cellular
chr3_-_61237050 0.69 ENST00000476844.1
ENST00000488467.1
ENST00000492590.1
ENST00000468189.1
FHIT
fragile histidine triad
chr7_+_133261209 0.68 ENST00000545148.1
EXOC4
exocyst complex component 4
chr3_+_171844762 0.68 ENST00000443501.1
FNDC3B
fibronectin type III domain containing 3B
chr17_-_37557846 0.67 ENST00000394294.3
ENST00000583610.1
ENST00000264658.6
FBXL20
F-box and leucine-rich repeat protein 20
chr12_+_131438496 0.67 ENST00000543826.1
GPR133
G protein-coupled receptor 133
chr21_-_16374688 0.67 ENST00000411932.1
NRIP1
nuclear receptor interacting protein 1
chr19_+_859654 0.66 ENST00000592860.1
CFD
complement factor D (adipsin)
chr14_+_23009190 0.66 ENST00000390532.1
TRAJ5
T cell receptor alpha joining 5
chr14_-_98444369 0.66 ENST00000554822.1
C14orf64
chromosome 14 open reading frame 64
chr9_+_12695702 0.66 ENST00000381136.2
TYRP1
tyrosinase-related protein 1
chr19_-_46526304 0.66 ENST00000008938.4
PGLYRP1
peptidoglycan recognition protein 1
chr20_-_36661826 0.65 ENST00000373448.2
ENST00000373447.3
TTI1
TELO2 interacting protein 1
chr2_+_201994208 0.65 ENST00000440180.1
CFLAR
CASP8 and FADD-like apoptosis regulator

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX21_TBR1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0055073 cadmium ion homeostasis(GO:0055073)
0.8 3.9 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.7 4.2 GO:0038112 interleukin-8-mediated signaling pathway(GO:0038112)
0.6 6.2 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.6 1.8 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.6 2.8 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.5 2.6 GO:0032474 otolith morphogenesis(GO:0032474)
0.5 2.0 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.4 2.2 GO:0051621 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.4 4.7 GO:0055009 atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.4 1.5 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.4 1.8 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.4 1.8 GO:1902304 positive regulation of potassium ion export(GO:1902304)
0.4 1.1 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.3 1.7 GO:0003070 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.3 1.7 GO:0048388 endosomal lumen acidification(GO:0048388)
0.3 0.8 GO:0019858 cytosine metabolic process(GO:0019858)
0.3 1.9 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.3 1.4 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.3 0.8 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.3 0.8 GO:0032289 central nervous system myelin formation(GO:0032289)
0.3 2.6 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.3 0.3 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092)
0.2 3.7 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.2 0.7 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) regulation of dendritic cell dendrite assembly(GO:2000547)
0.2 1.0 GO:0051541 elastin metabolic process(GO:0051541)
0.2 2.2 GO:0001661 conditioned taste aversion(GO:0001661)
0.2 0.7 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.2 0.7 GO:0061010 gall bladder development(GO:0061010)
0.2 1.1 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.2 0.9 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.2 0.7 GO:0001543 ovarian follicle rupture(GO:0001543)
0.2 0.7 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.2 0.7 GO:0051714 negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.2 7.1 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.2 0.6 GO:0003163 sinoatrial node development(GO:0003163) sinoatrial node cell differentiation(GO:0060921) sinoatrial node cell development(GO:0060931)
0.2 2.7 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.2 0.5 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.2 2.8 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.2 1.5 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.2 0.3 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.2 1.8 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.2 0.9 GO:1990523 bone regeneration(GO:1990523)
0.2 1.7 GO:2000334 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.2 1.8 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.1 1.2 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.1 1.0 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.1 0.8 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.1 0.4 GO:0006429 glutaminyl-tRNA aminoacylation(GO:0006425) leucyl-tRNA aminoacylation(GO:0006429)
0.1 0.5 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1 3.3 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.1 1.1 GO:1901295 positive regulation of ephrin receptor signaling pathway(GO:1901189) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1 1.6 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 0.4 GO:1901340 negative regulation of store-operated calcium channel activity(GO:1901340)
0.1 1.6 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 0.5 GO:0071288 cellular response to mercury ion(GO:0071288) positive regulation of mononuclear cell migration(GO:0071677) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.1 1.3 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.9 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.1 0.8 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1 0.5 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.1 0.6 GO:0032571 response to vitamin K(GO:0032571)
0.1 0.7 GO:0021633 optic nerve structural organization(GO:0021633)
0.1 0.3 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1 0.9 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.3 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.1 0.9 GO:1903826 arginine transmembrane transport(GO:1903826)
0.1 0.7 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 0.7 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1 1.5 GO:0035630 bone mineralization involved in bone maturation(GO:0035630)
0.1 0.8 GO:2000852 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.1 0.5 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.1 1.4 GO:0021860 pyramidal neuron development(GO:0021860)
0.1 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.1 0.8 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 1.2 GO:0030091 protein repair(GO:0030091)
0.1 0.6 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 1.5 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 0.4 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) positive regulation of interleukin-12 secretion(GO:2001184)
0.1 0.4 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.1 0.8 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.1 0.3 GO:0070433 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.1 0.2 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.1 1.0 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.1 0.2 GO:0048925 lateral line system development(GO:0048925)
0.1 0.9 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.3 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 0.4 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.1 1.6 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 7.0 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 0.1 GO:0015966 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
0.1 0.2 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.1 0.5 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.3 GO:0098907 protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907)
0.1 0.3 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.1 0.2 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1 1.0 GO:0044351 macropinocytosis(GO:0044351)
0.1 0.3 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.1 0.4 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 0.5 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.1 0.4 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.1 0.3 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.1 1.8 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 0.7 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.1 0.5 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.1 0.9 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.1 0.3 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.1 1.1 GO:0097264 self proteolysis(GO:0097264)
0.1 0.3 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.1 1.0 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 0.3 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.1 1.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.2 GO:0061433 cellular response to caloric restriction(GO:0061433) negative regulation of oligodendrocyte progenitor proliferation(GO:0070446)
0.1 0.6 GO:1902302 regulation of potassium ion export(GO:1902302)
0.1 0.6 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.1 0.7 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.1 1.0 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.1 0.8 GO:0030299 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.1 0.9 GO:0015884 folic acid transport(GO:0015884)
0.1 1.9 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.3 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0 0.5 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 1.4 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:0014908 myotube differentiation involved in skeletal muscle regeneration(GO:0014908)
0.0 0.5 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 0.6 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.0 2.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.4 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.5 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 1.0 GO:0007220 Notch receptor processing(GO:0007220)
0.0 7.7 GO:0046718 viral entry into host cell(GO:0046718)
0.0 0.4 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.3 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.4 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.7 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.4 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 1.6 GO:0097186 amelogenesis(GO:0097186)
0.0 0.6 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.2 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.2 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.3 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.3 GO:2001205 negative regulation of osteoclast development(GO:2001205)
0.0 0.5 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.2 GO:0060268 negative regulation of respiratory burst(GO:0060268)
0.0 0.4 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.4 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.2 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.5 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.9 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.7 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.3 GO:0009644 response to high light intensity(GO:0009644)
0.0 0.4 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.3 GO:0061366 negative regulation of growth hormone secretion(GO:0060125) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 2.0 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0 0.3 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.3 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.4 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.0 1.1 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.7 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.0 1.6 GO:0035411 catenin import into nucleus(GO:0035411)
0.0 0.2 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.0 0.5 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.8 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.1 GO:0009213 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.0 0.2 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0 0.9 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 4.6 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.2 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.7 GO:0006839 mitochondrial transport(GO:0006839)
0.0 0.1 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 2.1 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652)
0.0 0.3 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.0 0.1 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.6 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.9 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.4 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 1.1 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.9 GO:0006677 glycosylceramide metabolic process(GO:0006677)
0.0 2.3 GO:0007602 phototransduction(GO:0007602)
0.0 0.2 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.3 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.1 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.5 GO:0060134 prepulse inhibition(GO:0060134)
0.0 0.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.4 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.2 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.4 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.6 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.0 0.5 GO:0008228 opsonization(GO:0008228)
0.0 1.0 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.3 GO:0002820 negative regulation of adaptive immune response(GO:0002820)
0.0 0.7 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.2 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 1.3 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 1.5 GO:0014047 glutamate secretion(GO:0014047)
0.0 1.1 GO:0030101 natural killer cell activation(GO:0030101)
0.0 0.6 GO:0030033 microvillus assembly(GO:0030033)
0.0 0.1 GO:0001207 histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.0 1.7 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.3 GO:1904903 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.3 GO:0051828 entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.0 0.1 GO:0035803 egg coat formation(GO:0035803)
0.0 0.4 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.9 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.3 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.2 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.2 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.4 GO:2000398 regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.0 0.3 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0 1.7 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.1 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.9 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.0 0.4 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.3 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.2 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 1.2 GO:0021762 substantia nigra development(GO:0021762)
0.0 1.1 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.2 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.6 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.6 GO:0032006 regulation of TOR signaling(GO:0032006)
0.0 1.3 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.4 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0 0.2 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 1.9 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.0 GO:1990502 dense core granule maturation(GO:1990502)
0.0 1.1 GO:0006672 ceramide metabolic process(GO:0006672)
0.0 0.0 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.0 0.1 GO:0006404 RNA import into nucleus(GO:0006404) snRNA import into nucleus(GO:0061015)
0.0 0.2 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.3 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.2 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.5 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 0.1 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 1.4 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0 0.8 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.5 GO:0002209 behavioral fear response(GO:0001662) behavioral defense response(GO:0002209)
0.0 0.1 GO:0072402 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.0 0.9 GO:1901799 negative regulation of proteasomal protein catabolic process(GO:1901799)
0.0 0.7 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.1 GO:0032508 DNA duplex unwinding(GO:0032508)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0000920 cell separation after cytokinesis(GO:0000920)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 10.8 GO:0032982 myosin filament(GO:0032982)
0.3 3.0 GO:0005955 calcineurin complex(GO:0005955)
0.2 1.4 GO:0097441 basilar dendrite(GO:0097441)
0.2 2.6 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.2 1.9 GO:0035976 AP1 complex(GO:0035976)
0.2 1.8 GO:0043196 varicosity(GO:0043196)
0.2 1.6 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.2 0.8 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.1 6.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.5 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.1 2.0 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.7 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 1.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 1.4 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 0.5 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 1.1 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 0.4 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 0.2 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 1.7 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 0.6 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.1 0.5 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.1 3.3 GO:0042629 mast cell granule(GO:0042629)
0.1 0.9 GO:0070531 BRCA1-A complex(GO:0070531)
0.1 0.1 GO:0005683 U7 snRNP(GO:0005683)
0.1 1.6 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.1 1.2 GO:0071438 invadopodium membrane(GO:0071438)
0.1 1.6 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 0.7 GO:0032584 growth cone membrane(GO:0032584)
0.1 1.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 4.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 0.8 GO:0030427 site of polarized growth(GO:0030427)
0.1 1.1 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.4 GO:0031415 NatA complex(GO:0031415)
0.0 0.8 GO:0033010 paranodal junction(GO:0033010)
0.0 5.0 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 1.6 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.7 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.2 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.4 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 1.5 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 4.2 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.4 GO:0043219 lateral loop(GO:0043219)
0.0 0.3 GO:0043194 axon initial segment(GO:0043194)
0.0 1.0 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.9 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.5 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 2.8 GO:1904115 axon cytoplasm(GO:1904115)
0.0 2.0 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.7 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.5 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.2 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.8 GO:0005859 muscle myosin complex(GO:0005859)
0.0 2.4 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.2 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.2 GO:0097255 R2TP complex(GO:0097255)
0.0 0.3 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.4 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.4 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.9 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.5 GO:0017119 Golgi transport complex(GO:0017119)
0.0 3.8 GO:0035579 specific granule membrane(GO:0035579)
0.0 2.4 GO:0014704 intercalated disc(GO:0014704)
0.0 10.4 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.9 GO:0016459 myosin complex(GO:0016459)
0.0 0.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.4 GO:0070938 contractile ring(GO:0070938)
0.0 0.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.2 GO:0001652 granular component(GO:0001652)
0.0 0.1 GO:0005668 RNA polymerase transcription factor SL1 complex(GO:0005668)
0.0 0.3 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.2 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 1.1 GO:0000786 nucleosome(GO:0000786)
0.0 0.1 GO:0035101 FACT complex(GO:0035101)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 1.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 2.5 GO:0005776 autophagosome(GO:0005776)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.6 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.3 GO:0005687 U4 snRNP(GO:0005687)
0.0 3.8 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 4.5 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.9 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.6 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 2.4 GO:0032587 ruffle membrane(GO:0032587)
0.0 3.3 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 1.8 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 1.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.7 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.8 GO:0031983 vesicle lumen(GO:0031983) cytoplasmic membrane-bounded vesicle lumen(GO:0060205)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.3 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0001939 female pronucleus(GO:0001939) male pronucleus(GO:0001940)
0.0 2.9 GO:0030667 secretory granule membrane(GO:0030667)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.6 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
1.3 3.9 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
1.3 3.8 GO:0051139 metal ion:proton antiporter activity(GO:0051139)
0.7 4.2 GO:0004918 interleukin-8 receptor activity(GO:0004918)
0.6 5.3 GO:0017018 myosin phosphatase activity(GO:0017018)
0.4 2.2 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.4 2.0 GO:0070051 fibrinogen binding(GO:0070051)
0.3 2.3 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.3 1.6 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.3 1.8 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.2 0.5 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.2 1.0 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.2 2.2 GO:0042610 CD8 receptor binding(GO:0042610)
0.2 1.1 GO:0051373 FATZ binding(GO:0051373)
0.2 2.9 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.2 1.7 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2 0.6 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.2 6.2 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.2 1.8 GO:0030883 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.2 1.1 GO:0097001 ceramide binding(GO:0097001)
0.2 1.2 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.2 1.2 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.2 1.7 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.2 0.7 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.2 0.7 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.2 0.6 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.2 7.0 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.2 1.7 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.9 GO:0030109 HLA-B specific inhibitory MHC class I receptor activity(GO:0030109)
0.1 0.4 GO:0004823 glutamine-tRNA ligase activity(GO:0004819) leucine-tRNA ligase activity(GO:0004823)
0.1 0.9 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.7 GO:0039552 RIG-I binding(GO:0039552)
0.1 2.1 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 0.5 GO:0048030 disaccharide binding(GO:0048030)
0.1 1.4 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.1 0.5 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 2.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.8 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.1 3.1 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 1.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.7 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 0.3 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.1 0.8 GO:0071723 lipopeptide binding(GO:0071723)
0.1 0.8 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.9 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 0.9 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 2.2 GO:0015643 toxic substance binding(GO:0015643)
0.1 2.7 GO:0050811 GABA receptor binding(GO:0050811)
0.1 1.5 GO:0003796 lysozyme activity(GO:0003796)
0.1 0.2 GO:0031433 telethonin binding(GO:0031433)
0.1 0.2 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.1 0.8 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.5 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 9.0 GO:0001618 virus receptor activity(GO:0001618)
0.1 1.1 GO:0004896 cytokine receptor activity(GO:0004896)
0.1 0.5 GO:0004447 iodide peroxidase activity(GO:0004447)
0.1 0.5 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 3.0 GO:0005123 death receptor binding(GO:0005123)
0.1 0.2 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 2.1 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 0.7 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 0.6 GO:0001851 complement component C3b binding(GO:0001851)
0.1 0.8 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.5 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.5 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.4 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 0.7 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 0.3 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 1.5 GO:0008494 translation activator activity(GO:0008494)
0.1 4.6 GO:0019843 rRNA binding(GO:0019843)
0.1 1.1 GO:0000150 recombinase activity(GO:0000150)
0.1 1.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.3 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 0.2 GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.8 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 1.5 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 1.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.4 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 7.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 1.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.5 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 1.5 GO:0071837 HMG box domain binding(GO:0071837)
0.0 1.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 1.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 2.8 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 1.0 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 2.4 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.9 GO:0005542 folic acid binding(GO:0005542)
0.0 2.8 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.8 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.3 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.4 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 0.2 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.0 1.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.9 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.7 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 1.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.3 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.4 GO:0051525 NFAT protein binding(GO:0051525)
0.0 1.4 GO:0005521 lamin binding(GO:0005521)
0.0 0.4 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.3 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.2 GO:0034061 DNA polymerase activity(GO:0034061)
0.0 1.5 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.5 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.2 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 1.0 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 1.1 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.9 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.5 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.3 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.9 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.6 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.8 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 1.0 GO:0070888 E-box binding(GO:0070888)
0.0 2.3 GO:0016279 protein-lysine N-methyltransferase activity(GO:0016279)
0.0 0.9 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.4 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 1.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.7 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.2 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.4 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.1 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.0 0.2 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.7 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.6 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 1.0 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.1 GO:0070628 proteasome binding(GO:0070628)
0.0 0.2 GO:0008308 voltage-gated anion channel activity(GO:0008308)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.7 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.4 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.7 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.0 0.5 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.2 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.4 GO:0019841 retinol binding(GO:0019841)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.6 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.5 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.1 GO:0003947 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity(GO:0003947)
0.0 0.3 GO:0051400 BH domain binding(GO:0051400)
0.0 0.4 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.4 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.1 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.2 GO:0048156 tau protein binding(GO:0048156)
0.0 0.6 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.9 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.5 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.4 GO:0042169 SH2 domain binding(GO:0042169)
0.0 1.3 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.1 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.3 GO:0070016 armadillo repeat domain binding(GO:0070016)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 4.2 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 11.4 PID FGF PATHWAY FGF signaling pathway
0.1 0.9 PID IL1 PATHWAY IL1-mediated signaling events
0.1 2.7 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 2.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 2.0 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 1.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 2.9 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 1.6 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 0.9 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 4.6 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.6 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.9 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.5 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 1.8 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.9 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.0 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 3.3 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 2.0 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 3.1 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 1.1 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.4 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.9 PID INSULIN PATHWAY Insulin Pathway
0.0 0.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.8 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.8 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.1 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.9 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.3 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 1.5 PID FOXO PATHWAY FoxO family signaling
0.0 2.5 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.7 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 2.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.7 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.4 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.4 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 4.2 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.3 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.9 PID ATM PATHWAY ATM pathway
0.0 0.5 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.3 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 1.5 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 1.1 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.5 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.8 PID AURORA B PATHWAY Aurora B signaling
0.0 0.1 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 11.6 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.1 2.9 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 2.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 2.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 4.8 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 3.0 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 3.3 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 6.2 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 0.9 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 3.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 1.8 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 2.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 0.8 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 1.1 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.1 1.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 3.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 4.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 6.0 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.0 0.8 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 1.3 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 3.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 2.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 2.2 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.0 1.0 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 1.9 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.0 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 1.5 REACTOME CD28 CO STIMULATION Genes involved in CD28 co-stimulation
0.0 0.6 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 3.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.7 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 2.8 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.5 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.7 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.4 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.5 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 3.5 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 1.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.9 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.9 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.8 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 1.0 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.6 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.0 0.3 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 1.0 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.8 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.6 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.0 0.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.0 REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE Genes involved in MyD88:Mal cascade initiated on plasma membrane
0.0 0.2 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.5 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.7 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer