ISMARA results: TBX21

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Illumina Body Map 2: averaged replicates

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Results for TBX21_TBR1

Z-value: 1.52

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Transcription factors associated with TBX21_TBR1

Gene Symbol	Gene ID	Gene Info
TBX21 Ensembl NCBI GeneCards UniProt	ENSG00000073861.2	T-box transcription factor 21
TBR1 Ensembl NCBI GeneCards UniProt	ENSG00000136535.10	T-box brain transcription factor 1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
TBX21	hg19_v2_chr17_+_45810594_45810610	0.38	3.0e-02	Click!
TBR1	hg19_v2_chr2_+_162272605_162272753	-0.03	8.7e-01	Click!

Activity profile of TBX21_TBR1 motif

Sorted Z-values of TBX21_TBR1 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr8_+_1993173 Show fit	4.88	ENST00000523438.1	MYOM2 Ensembl NCBI GeneCards UniProt Show fit	myomesin 2
chr14_-_23876801 Show fit	4.53	ENST00000356287.3	MYH6 Ensembl NCBI GeneCards UniProt Show fit	myosin, heavy chain 6, cardiac muscle, alpha
chr2_-_219031709 Show fit	4.16	ENST00000295683.2	CXCR1 Ensembl NCBI GeneCards UniProt Show fit	chemokine (C-X-C motif) receptor 1
chr21_+_30503282 Show fit	3.95	ENST00000399925.1	MAP3K7CL Ensembl NCBI GeneCards UniProt Show fit	MAP3K7 C-terminal like
chr11_+_112832202 Show fit	3.58	ENST00000534015.1	NCAM1 Ensembl NCBI GeneCards UniProt Show fit	neural cell adhesion molecule 1
chr22_+_18593097 Show fit	3.26	ENST00000426208.1	TUBA8 Ensembl NCBI GeneCards UniProt Show fit	tubulin, alpha 8
chr21_+_30502806 Show fit	3.21	ENST00000399928.1 ENST00000399926.1	MAP3K7CL Ensembl NCBI GeneCards UniProt Show fit	MAP3K7 C-terminal like
chr10_-_75226166 Show fit	3.05	ENST00000544628.1	PPP3CB Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 3, catalytic subunit, beta isozyme
chr5_+_54320078 Show fit	2.99	ENST00000231009.2	GZMK Ensembl NCBI GeneCards UniProt Show fit	granzyme K (granzyme 3; tryptase II)
chr9_-_71161505 Show fit	2.93	ENST00000446290.1	RP11-274B18.2 Ensembl NCBI GeneCards UniProt Show fit	RP11-274B18.2
chr7_+_143013198 Show fit	2.85	ENST00000343257.2	CLCN1 Ensembl NCBI GeneCards UniProt Show fit	chloride channel, voltage-sensitive 1
chr11_+_112832090 Show fit	2.81	ENST00000533760.1	NCAM1 Ensembl NCBI GeneCards UniProt Show fit	neural cell adhesion molecule 1
chr3_+_42190714 Show fit	2.74	ENST00000449246.1	TRAK1 Ensembl NCBI GeneCards UniProt Show fit	trafficking protein, kinesin binding 1
chr11_+_112832133 Show fit	2.68	ENST00000524665.1	NCAM1 Ensembl NCBI GeneCards UniProt Show fit	neural cell adhesion molecule 1
chr2_+_219247021 Show fit	2.68	ENST00000539932.1	SLC11A1 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
chrY_+_2709527 Show fit	2.43	ENST00000250784.8	RPS4Y1 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S4, Y-linked 1
chr7_-_36764004 Show fit	2.34	ENST00000431169.1	AOAH Ensembl NCBI GeneCards UniProt Show fit	acyloxyacyl hydrolase (neutrophil)
chr6_-_130536774 Show fit	2.32	ENST00000532763.1	SAMD3 Ensembl NCBI GeneCards UniProt Show fit	sterile alpha motif domain containing 3
chr7_-_36764062 Show fit	2.16	ENST00000435386.1	AOAH Ensembl NCBI GeneCards UniProt Show fit	acyloxyacyl hydrolase (neutrophil)
chrY_+_2709906 Show fit	2.15	ENST00000430575.1	RPS4Y1 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S4, Y-linked 1
chr7_-_36764142 Show fit	2.07	ENST00000258749.5 ENST00000535891.1	AOAH Ensembl NCBI GeneCards UniProt Show fit	acyloxyacyl hydrolase (neutrophil)
chr17_-_42452063 Show fit	2.00	ENST00000588098.1	ITGA2B Ensembl NCBI GeneCards UniProt Show fit	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
chr11_+_122709200 Show fit	1.98	ENST00000227348.4	CRTAM Ensembl NCBI GeneCards UniProt Show fit	cytotoxic and regulatory T cell molecule
chr22_-_31688431 Show fit	1.98	ENST00000402249.3 ENST00000443175.1 ENST00000215912.5 ENST00000441972.1	PIK3IP1 Ensembl NCBI GeneCards UniProt Show fit	phosphoinositide-3-kinase interacting protein 1
chr11_+_64073699 Show fit	1.97	ENST00000405666.1 ENST00000468670.1	ESRRA Ensembl NCBI GeneCards UniProt Show fit	estrogen-related receptor alpha
chr7_+_110731062 Show fit	1.96	ENST00000308478.5 ENST00000451085.1 ENST00000422987.3 ENST00000421101.1	LRRN3 Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat neuronal 3
chrX_-_19689106 Show fit	1.91	ENST00000379716.1	SH3KBP1 Ensembl NCBI GeneCards UniProt Show fit	SH3-domain kinase binding protein 1
chr22_-_31688381 Show fit	1.90	ENST00000487265.2	PIK3IP1 Ensembl NCBI GeneCards UniProt Show fit	phosphoinositide-3-kinase interacting protein 1
chr11_+_61447845 Show fit	1.84	ENST00000257215.5	DAGLA Ensembl NCBI GeneCards UniProt Show fit	diacylglycerol lipase, alpha
chr7_-_142240014 Show fit	1.83	ENST00000390363.2	TRBV9 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor beta variable 9
chr2_-_40679186 Show fit	1.82	ENST00000406785.2	SLC8A1 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 8 (sodium/calcium exchanger), member 1
chr1_-_11907829 Show fit	1.81	ENST00000376480.3	NPPA Ensembl NCBI GeneCards UniProt Show fit	natriuretic peptide A
chr22_+_40441456 Show fit	1.81	ENST00000402203.1	TNRC6B Ensembl NCBI GeneCards UniProt Show fit	trinucleotide repeat containing 6B
chr1_-_25256368 Show fit	1.77	ENST00000308873.6	RUNX3 Ensembl NCBI GeneCards UniProt Show fit	runt-related transcription factor 3
chr6_-_160166218 Show fit	1.71	ENST00000537657.1	SOD2 Ensembl NCBI GeneCards UniProt Show fit	superoxide dismutase 2, mitochondrial
chr1_-_154167124 Show fit	1.70	ENST00000515609.1	TPM3 Ensembl NCBI GeneCards UniProt Show fit	tropomyosin 3
chr5_-_39270725 Show fit	1.68	ENST00000512138.1 ENST00000512982.1 ENST00000540520.1	FYB Ensembl NCBI GeneCards UniProt Show fit	FYN binding protein
chr7_+_80253387 Show fit	1.68	ENST00000438020.1	CD36 Ensembl NCBI GeneCards UniProt Show fit	CD36 molecule (thrombospondin receptor)
chr1_+_202995611 Show fit	1.67	ENST00000367240.2	PPFIA4 Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
chr17_-_43502987 Show fit	1.58	ENST00000376922.2	ARHGAP27 Ensembl NCBI GeneCards UniProt Show fit	Rho GTPase activating protein 27
chr10_-_126432821 Show fit	1.58	ENST00000280780.6	FAM53B Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 53, member B
chr1_-_36947652 Show fit	1.55	ENST00000533491.1	CSF3R Ensembl NCBI GeneCards UniProt Show fit	colony stimulating factor 3 receptor (granulocyte)
chr14_+_77582905 Show fit	1.55	ENST00000557408.1	TMEM63C Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 63C
chrX_+_47050798 Show fit	1.53	ENST00000412206.1 ENST00000427561.1	UBA1 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin-like modifier activating enzyme 1
chr12_+_69742121 Show fit	1.53	ENST00000261267.2 ENST00000549690.1 ENST00000548839.1	LYZ Ensembl NCBI GeneCards UniProt Show fit	lysozyme
chr12_-_90024360 Show fit	1.50	ENST00000393164.2	ATP2B1 Ensembl NCBI GeneCards UniProt Show fit	ATPase, Ca++ transporting, plasma membrane 1
chr1_-_205290865 Show fit	1.48	ENST00000367157.3	NUAK2 Ensembl NCBI GeneCards UniProt Show fit	NUAK family, SNF1-like kinase, 2
chr15_-_38852251 Show fit	1.47	ENST00000558432.1	RASGRP1 Ensembl NCBI GeneCards UniProt Show fit	RAS guanyl releasing protein 1 (calcium and DAG-regulated)
chr12_-_89746264 Show fit	1.47	ENST00000548755.1	DUSP6 Ensembl NCBI GeneCards UniProt Show fit	dual specificity phosphatase 6
chr12_-_89746173 Show fit	1.44	ENST00000308385.6	DUSP6 Ensembl NCBI GeneCards UniProt Show fit	dual specificity phosphatase 6
chr1_+_172628154 Show fit	1.42	ENST00000340030.3 ENST00000367721.2	FASLG Ensembl NCBI GeneCards UniProt Show fit	Fas ligand (TNF superfamily, member 6)
chr17_-_72619783 Show fit	1.42	ENST00000328630.3	CD300E Ensembl NCBI GeneCards UniProt Show fit	CD300e molecule
chr12_+_58148842 Show fit	1.39	ENST00000266643.5	MARCH9 Ensembl NCBI GeneCards UniProt Show fit	membrane-associated ring finger (C3HC4) 9
chr5_-_131132658 Show fit	1.37	ENST00000514667.1 ENST00000511848.1 ENST00000510461.1	CTC-432M15.3 Ensembl NCBI GeneCards UniProt Show fit FNIP1 Ensembl NCBI GeneCards UniProt Show fit	Folliculin-interacting protein 1 folliculin interacting protein 1
chr8_+_1993152 Show fit	1.36	ENST00000262113.4	MYOM2 Ensembl NCBI GeneCards UniProt Show fit	myomesin 2
chr3_-_66551351 Show fit	1.36	ENST00000273261.3	LRIG1 Ensembl NCBI GeneCards UniProt Show fit	leucine-rich repeats and immunoglobulin-like domains 1
chr6_+_167536230 Show fit	1.35	ENST00000341935.5 ENST00000349984.4	CCR6 Ensembl NCBI GeneCards UniProt Show fit	chemokine (C-C motif) receptor 6
chr10_+_135050908 Show fit	1.34	ENST00000325980.9	VENTX Ensembl NCBI GeneCards UniProt Show fit	VENT homeobox
chr1_-_156786530 Show fit	1.33	ENST00000368198.3	SH2D2A Ensembl NCBI GeneCards UniProt Show fit	SH2 domain containing 2A
chr22_+_40342819 Show fit	1.33	ENST00000407075.3	GRAP2 Ensembl NCBI GeneCards UniProt Show fit	GRB2-related adaptor protein 2
chr1_-_156786634 Show fit	1.32	ENST00000392306.2 ENST00000368199.3	SH2D2A Ensembl NCBI GeneCards UniProt Show fit	SH2 domain containing 2A
chrX_+_109245863 Show fit	1.30	ENST00000372072.3	TMEM164 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 164
chr3_-_66551397 Show fit	1.28	ENST00000383703.3	LRIG1 Ensembl NCBI GeneCards UniProt Show fit	leucine-rich repeats and immunoglobulin-like domains 1
chr7_-_142120321 Show fit	1.25	ENST00000390377.1	TRBV7-7 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor beta variable 7-7
chr8_-_101724989 Show fit	1.23	ENST00000517403.1	PABPC1 Ensembl NCBI GeneCards UniProt Show fit	poly(A) binding protein, cytoplasmic 1
chr10_-_76868931 Show fit	1.22	ENST00000372700.3 ENST00000473072.2 ENST00000491677.2 ENST00000607131.1 ENST00000372702.3	DUSP13 Ensembl NCBI GeneCards UniProt Show fit	dual specificity phosphatase 13
chr4_-_90757364 Show fit	1.20	ENST00000508895.1	SNCA Ensembl NCBI GeneCards UniProt Show fit	synuclein, alpha (non A4 component of amyloid precursor)
chr11_+_73358690 Show fit	1.19	ENST00000545798.1 ENST00000539157.1 ENST00000546251.1 ENST00000535582.1 ENST00000538227.1 ENST00000543524.1	PLEKHB1 Ensembl NCBI GeneCards UniProt Show fit	pleckstrin homology domain containing, family B (evectins) member 1
chr12_+_65672702 Show fit	1.19	ENST00000538045.1 ENST00000535239.1	MSRB3 Ensembl NCBI GeneCards UniProt Show fit	methionine sulfoxide reductase B3
chr11_+_59824060 Show fit	1.18	ENST00000395032.2 ENST00000358152.2	MS4A3 Ensembl NCBI GeneCards UniProt Show fit	membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr17_-_72619869 Show fit	1.17	ENST00000392619.1 ENST00000426295.2	CD300E Ensembl NCBI GeneCards UniProt Show fit	CD300e molecule
chr7_+_123241908 Show fit	1.16	ENST00000434204.1 ENST00000437535.1 ENST00000451215.1	ASB15 Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat and SOCS box containing 15
chr11_+_64950801 Show fit	1.14	ENST00000526468.1	CAPN1 Ensembl NCBI GeneCards UniProt Show fit	calpain 1, (mu/I) large subunit
chr5_+_150040403 Show fit	1.14	ENST00000517768.1 ENST00000297130.4	MYOZ3 Ensembl NCBI GeneCards UniProt Show fit	myozenin 3
chrX_+_123480375 Show fit	1.14	ENST00000360027.4	SH2D1A Ensembl NCBI GeneCards UniProt Show fit	SH2 domain containing 1A
chrX_+_123480421 Show fit	1.12	ENST00000477673.2	SH2D1A Ensembl NCBI GeneCards UniProt Show fit	SH2 domain containing 1A
chr11_-_133826852 Show fit	1.10	ENST00000533871.2 ENST00000321016.8	IGSF9B Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin superfamily, member 9B
chrX_+_123480194 Show fit	1.10	ENST00000371139.4	SH2D1A Ensembl NCBI GeneCards UniProt Show fit	SH2 domain containing 1A
chr16_+_27413483 Show fit	1.10	ENST00000337929.3 ENST00000564089.1	IL21R Ensembl NCBI GeneCards UniProt Show fit	interleukin 21 receptor
chr4_+_160188889 Show fit	1.10	ENST00000264431.4	RAPGEF2 Ensembl NCBI GeneCards UniProt Show fit	Rap guanine nucleotide exchange factor (GEF) 2
chr8_-_66754172 Show fit	1.09	ENST00000401827.3	PDE7A Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 7A
chr2_+_219246746 Show fit	1.09	ENST00000233202.6	SLC11A1 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
chr12_-_111180644 Show fit	1.09	ENST00000551676.1 ENST00000550991.1 ENST00000335007.5 ENST00000340766.5	PPP1CC Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1, catalytic subunit, gamma isozyme
chr7_-_44179972 Show fit	1.08	ENST00000446581.1	MYL7 Ensembl NCBI GeneCards UniProt Show fit	myosin, light chain 7, regulatory
chr8_-_143833918 Show fit	1.08	ENST00000359228.3	LYPD2 Ensembl NCBI GeneCards UniProt Show fit	LY6/PLAUR domain containing 2
chr10_+_45406627 Show fit	1.08	ENST00000389583.4	TMEM72 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 72
chr17_-_9929581 Show fit	1.06	ENST00000437099.2 ENST00000396115.2	GAS7 Ensembl NCBI GeneCards UniProt Show fit	growth arrest-specific 7
chr5_-_74807418 Show fit	1.06	ENST00000405807.4 ENST00000261415.7	COL4A3BP Ensembl NCBI GeneCards UniProt Show fit	collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
chr2_+_87808725 Show fit	1.06	ENST00000413202.1	LINC00152 Ensembl NCBI GeneCards UniProt Show fit	long intergenic non-protein coding RNA 152
chr3_+_101498269 Show fit	1.06	ENST00000491511.2	NXPE3 Ensembl NCBI GeneCards UniProt Show fit	neurexophilin and PC-esterase domain family, member 3
chr3_+_50654821 Show fit	1.05	ENST00000457064.1	MAPKAPK3 Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase-activated protein kinase 3
chr12_+_10183271 Show fit	1.03	ENST00000355819.1	CLEC9A Ensembl NCBI GeneCards UniProt Show fit	C-type lectin domain family 9, member A
chr15_+_40861487 Show fit	1.03	ENST00000315616.7 ENST00000559271.1	RPUSD2 Ensembl NCBI GeneCards UniProt Show fit	RNA pseudouridylate synthase domain containing 2
chr6_-_13487825 Show fit	1.03	ENST00000603223.1	GFOD1 Ensembl NCBI GeneCards UniProt Show fit	glucose-fructose oxidoreductase domain containing 1
chr17_+_34538310 Show fit	1.02	ENST00000444414.1 ENST00000378350.4 ENST00000389068.5 ENST00000588929.1 ENST00000589079.1 ENST00000589336.1 ENST00000400702.4 ENST00000591167.1 ENST00000586598.1 ENST00000591637.1 ENST00000378352.4 ENST00000358756.5	CCL4L1 Ensembl NCBI GeneCards UniProt Show fit	chemokine (C-C motif) ligand 4-like 1
chr15_+_41913690 Show fit	1.02	ENST00000563576.1	MGA Ensembl NCBI GeneCards UniProt Show fit	MGA, MAX dimerization protein
chr1_-_158300747 Show fit	1.02	ENST00000451207.1	CD1B Ensembl NCBI GeneCards UniProt Show fit	CD1b molecule
chr5_-_49737184 Show fit	1.01	ENST00000508934.1 ENST00000303221.5	EMB Ensembl NCBI GeneCards UniProt Show fit	embigin
chr13_+_76378305 Show fit	1.01	ENST00000526371.1 ENST00000526528.1	LMO7 Ensembl NCBI GeneCards UniProt Show fit	LIM domain 7
chr1_+_203256898 Show fit	1.00	ENST00000433008.1	RP11-134P9.3 Ensembl NCBI GeneCards UniProt Show fit	RP11-134P9.3
chr1_-_11024258 Show fit	0.98	ENST00000418570.2	C1orf127 Ensembl NCBI GeneCards UniProt Show fit	chromosome 1 open reading frame 127
chr11_+_59824127 Show fit	0.97	ENST00000278865.3	MS4A3 Ensembl NCBI GeneCards UniProt Show fit	membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
chr9_+_34990219 Show fit	0.97	ENST00000541010.1 ENST00000454002.2 ENST00000545841.1	DNAJB5 Ensembl NCBI GeneCards UniProt Show fit	DnaJ (Hsp40) homolog, subfamily B, member 5
chr4_-_90756769 Show fit	0.96	ENST00000345009.4 ENST00000505199.1 ENST00000502987.1	SNCA Ensembl NCBI GeneCards UniProt Show fit	synuclein, alpha (non A4 component of amyloid precursor)
chr14_-_62217779 Show fit	0.96	ENST00000554254.1	HIF1A-AS2 Ensembl NCBI GeneCards UniProt Show fit	HIF1A antisense RNA 2
chr10_-_23003460 Show fit	0.96	ENST00000376573.4	PIP4K2A Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr1_+_40840320 Show fit	0.96	ENST00000372708.1	SMAP2 Ensembl NCBI GeneCards UniProt Show fit	small ArfGAP2
chr14_+_98602380 Show fit	0.95	ENST00000557072.1	RP11-61O1.2 Ensembl NCBI GeneCards UniProt Show fit	RP11-61O1.2
chr1_+_154975110 Show fit	0.95	ENST00000535420.1 ENST00000368426.3	ZBTB7B Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 7B
chr16_+_50313426 Show fit	0.95	ENST00000569265.1	ADCY7 Ensembl NCBI GeneCards UniProt Show fit	adenylate cyclase 7
chr17_-_47308128 Show fit	0.95	ENST00000413580.1 ENST00000511066.1	PHOSPHO1 Ensembl NCBI GeneCards UniProt Show fit	phosphatase, orphan 1
chr2_+_201994042 Show fit	0.94	ENST00000417748.1	CFLAR Ensembl NCBI GeneCards UniProt Show fit	CASP8 and FADD-like apoptosis regulator
chr1_+_202172848 Show fit	0.94	ENST00000255432.7	LGR6 Ensembl NCBI GeneCards UniProt Show fit	leucine-rich repeat containing G protein-coupled receptor 6
chr17_-_36884451 Show fit	0.94	ENST00000595377.1	AC006449.1 Ensembl NCBI GeneCards UniProt Show fit	NS5ATP13TP1; Uncharacterized protein
chr21_-_31864275 Show fit	0.93	ENST00000334063.4	KRTAP19-3 Ensembl NCBI GeneCards UniProt Show fit	keratin associated protein 19-3
chr11_+_73358594 Show fit	0.93	ENST00000227214.6 ENST00000398494.4 ENST00000543085.1	PLEKHB1 Ensembl NCBI GeneCards UniProt Show fit	pleckstrin homology domain containing, family B (evectins) member 1
chr12_+_66582919 Show fit	0.93	ENST00000545837.1 ENST00000457197.2	IRAK3 Ensembl NCBI GeneCards UniProt Show fit	interleukin-1 receptor-associated kinase 3
chr1_+_184356188 Show fit	0.92	ENST00000235307.6	C1orf21 Ensembl NCBI GeneCards UniProt Show fit	chromosome 1 open reading frame 21
chr12_-_68553512 Show fit	0.92	ENST00000229135.3	IFNG Ensembl NCBI GeneCards UniProt Show fit	interferon, gamma
chr19_+_12862604 Show fit	0.92	ENST00000553030.1	BEST2 Ensembl NCBI GeneCards UniProt Show fit	bestrophin 2
chr2_-_113594279 Show fit	0.92	ENST00000416750.1 ENST00000418817.1 ENST00000263341.2	IL1B Ensembl NCBI GeneCards UniProt Show fit	interleukin 1, beta
chr12_+_14572070 Show fit	0.92	ENST00000545769.1 ENST00000428217.2 ENST00000396279.2 ENST00000542514.1 ENST00000536279.1	ATF7IP Ensembl NCBI GeneCards UniProt Show fit	activating transcription factor 7 interacting protein
chr13_-_30160925 Show fit	0.91	ENST00000450494.1	SLC7A1 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr1_+_76540386 Show fit	0.91	ENST00000328299.3	ST6GALNAC3 Ensembl NCBI GeneCards UniProt Show fit	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr10_-_65028938 Show fit	0.91	ENST00000402544.1	JMJD1C Ensembl NCBI GeneCards UniProt Show fit	jumonji domain containing 1C
chr11_+_71846764 Show fit	0.91	ENST00000456237.1 ENST00000442948.2 ENST00000546166.1	FOLR3 Ensembl NCBI GeneCards UniProt Show fit	folate receptor 3 (gamma)
chr6_+_45390222 Show fit	0.90	ENST00000359524.5	RUNX2 Ensembl NCBI GeneCards UniProt Show fit	runt-related transcription factor 2
chr13_+_42031679 Show fit	0.89	ENST00000379359.3	RGCC Ensembl NCBI GeneCards UniProt Show fit	regulator of cell cycle
chr14_+_22433675 Show fit	0.89	ENST00000390442.3	TRAV12-3 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor alpha variable 12-3
chr20_+_58630972 Show fit	0.89	ENST00000313426.1	C20orf197 Ensembl NCBI GeneCards UniProt Show fit	chromosome 20 open reading frame 197
chr19_+_55235969 Show fit	0.88	ENST00000402254.2 ENST00000538269.1 ENST00000541392.1 ENST00000291860.1 ENST00000396284.2	KIR3DL1 Ensembl NCBI GeneCards UniProt Show fit KIR3DL3 Ensembl NCBI GeneCards UniProt Show fit KIR2DL4 Ensembl NCBI GeneCards UniProt Show fit	killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
chr16_+_6069072 Show fit	0.87	ENST00000547605.1 ENST00000550418.1 ENST00000553186.1	RBFOX1 Ensembl NCBI GeneCards UniProt Show fit	RNA binding protein, fox-1 homolog (C. elegans) 1
chr4_-_5991545 Show fit	0.86	ENST00000531445.1	C4orf50 Ensembl NCBI GeneCards UniProt Show fit	chromosome 4 open reading frame 50
chr12_+_11905413 Show fit	0.86	ENST00000545027.1	ETV6 Ensembl NCBI GeneCards UniProt Show fit	ets variant 6
chr7_+_77469439 Show fit	0.85	ENST00000450574.1 ENST00000416283.2 ENST00000248550.7	PHTF2 Ensembl NCBI GeneCards UniProt Show fit	putative homeodomain transcription factor 2
chr7_+_31726822 Show fit	0.84	ENST00000409146.3	PPP1R17 Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1, regulatory subunit 17
chr7_+_107110488 Show fit	0.84	ENST00000304402.4	GPR22 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 22
chr11_-_33913708 Show fit	0.84	ENST00000257818.2	LMO2 Ensembl NCBI GeneCards UniProt Show fit	LIM domain only 2 (rhombotin-like 1)
chr7_+_142012967 Show fit	0.84	ENST00000390357.3	TRBV4-1 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor beta variable 4-1
chr10_-_76868866 Show fit	0.83	ENST00000607487.1	DUSP13 Ensembl NCBI GeneCards UniProt Show fit	dual specificity phosphatase 13
chr4_+_108746282 Show fit	0.83	ENST00000503862.1	SGMS2 Ensembl NCBI GeneCards UniProt Show fit	sphingomyelin synthase 2
chr1_+_32716857 Show fit	0.82	ENST00000482949.1 ENST00000495610.2	LCK Ensembl NCBI GeneCards UniProt Show fit	lymphocyte-specific protein tyrosine kinase
chr1_+_20915409 Show fit	0.82	ENST00000375071.3	CDA Ensembl NCBI GeneCards UniProt Show fit	cytidine deaminase
chr3_-_44465475 Show fit	0.81	ENST00000416124.1	LINC00694 Ensembl NCBI GeneCards UniProt Show fit	long intergenic non-protein coding RNA 694
chr13_+_32634993 Show fit	0.81	ENST00000436046.1	FRY Ensembl NCBI GeneCards UniProt Show fit	furry homolog (Drosophila)
chr16_+_30386098 Show fit	0.80	ENST00000322861.7	MYLPF Ensembl NCBI GeneCards UniProt Show fit	myosin light chain, phosphorylatable, fast skeletal muscle
chr5_-_88180342 Show fit	0.80	ENST00000502983.1	MEF2C Ensembl NCBI GeneCards UniProt Show fit	myocyte enhancer factor 2C
chr2_+_120687335 Show fit	0.80	ENST00000544261.1	PTPN4 Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr7_+_150264365 Show fit	0.80	ENST00000255945.2 ENST00000461940.1	GIMAP4 Ensembl NCBI GeneCards UniProt Show fit	GTPase, IMAP family member 4
chr4_-_8073554 Show fit	0.79	ENST00000510277.1	ABLIM2 Ensembl NCBI GeneCards UniProt Show fit	actin binding LIM protein family, member 2
chr3_+_107243204 Show fit	0.79	ENST00000456817.1 ENST00000458458.1	BBX Ensembl NCBI GeneCards UniProt Show fit	bobby sox homolog (Drosophila)
chr17_-_76713100 Show fit	0.79	ENST00000585509.1	CYTH1 Ensembl NCBI GeneCards UniProt Show fit	cytohesin 1
chr4_+_154622652 Show fit	0.79	ENST00000260010.6	TLR2 Ensembl NCBI GeneCards UniProt Show fit	toll-like receptor 2
chr1_+_158325684 Show fit	0.79	ENST00000368162.2	CD1E Ensembl NCBI GeneCards UniProt Show fit	CD1e molecule
chr2_-_25391507 Show fit	0.79	ENST00000380794.1	POMC Ensembl NCBI GeneCards UniProt Show fit	proopiomelanocortin
chr11_+_107799118 Show fit	0.78	ENST00000320578.2	RAB39A Ensembl NCBI GeneCards UniProt Show fit	RAB39A, member RAS oncogene family
chr10_-_16563870 Show fit	0.78	ENST00000298943.3	C1QL3 Ensembl NCBI GeneCards UniProt Show fit	complement component 1, q subcomponent-like 3
chr14_+_75746664 Show fit	0.78	ENST00000557139.1	FOS Ensembl NCBI GeneCards UniProt Show fit	FBJ murine osteosarcoma viral oncogene homolog
chr7_-_142224280 Show fit	0.77	ENST00000390367.3	TRBV11-1 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor beta variable 11-1
chr1_+_32716840 Show fit	0.77	ENST00000336890.5	LCK Ensembl NCBI GeneCards UniProt Show fit	lymphocyte-specific protein tyrosine kinase
chr6_-_13487784 Show fit	0.77	ENST00000379287.3	GFOD1 Ensembl NCBI GeneCards UniProt Show fit	glucose-fructose oxidoreductase domain containing 1
chr1_-_36020531 Show fit	0.77	ENST00000440579.1 ENST00000494948.1	KIAA0319L Ensembl NCBI GeneCards UniProt Show fit	KIAA0319-like
chr2_+_29001711 Show fit	0.76	ENST00000418910.1	PPP1CB Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1, catalytic subunit, beta isozyme
chr7_+_150264470 Show fit	0.76	ENST00000479232.1	GIMAP4 Ensembl NCBI GeneCards UniProt Show fit	GTPase, IMAP family member 4
chr10_+_118305435 Show fit	0.76	ENST00000369221.2	PNLIP Ensembl NCBI GeneCards UniProt Show fit	pancreatic lipase
chr7_+_107220660 Show fit	0.76	ENST00000465919.1 ENST00000445771.2 ENST00000479917.1 ENST00000421217.1 ENST00000457837.1	BCAP29 Ensembl NCBI GeneCards UniProt Show fit	B-cell receptor-associated protein 29
chr12_-_91348949 Show fit	0.75	ENST00000358859.2	CCER1 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil glutamate-rich protein 1
chr17_+_75084717 Show fit	0.75	ENST00000561721.2 ENST00000589827.1 ENST00000392476.2	SEC14L1 Ensembl NCBI GeneCards UniProt Show fit	SEC14-like 1 (S. cerevisiae)
chr6_-_6225026 Show fit	0.75	ENST00000445223.1	F13A1 Ensembl NCBI GeneCards UniProt Show fit	coagulation factor XIII, A1 polypeptide
chr6_+_45389893 Show fit	0.74	ENST00000371432.3	RUNX2 Ensembl NCBI GeneCards UniProt Show fit	runt-related transcription factor 2
chr5_+_94727048 Show fit	0.74	ENST00000283357.5	FAM81B Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 81, member B
chr17_-_38721711 Show fit	0.73	ENST00000578085.1 ENST00000246657.2	CCR7 Ensembl NCBI GeneCards UniProt Show fit	chemokine (C-C motif) receptor 7
chr1_-_11042094 Show fit	0.73	ENST00000377004.4 ENST00000377008.4	C1orf127 Ensembl NCBI GeneCards UniProt Show fit	chromosome 1 open reading frame 127
chr1_+_174843548 Show fit	0.72	ENST00000478442.1 ENST00000465412.1	RABGAP1L Ensembl NCBI GeneCards UniProt Show fit	RAB GTPase activating protein 1-like
chr19_-_51875894 Show fit	0.72	ENST00000600427.1 ENST00000595217.1 ENST00000221978.5	NKG7 Ensembl NCBI GeneCards UniProt Show fit	natural killer cell group 7 sequence
chr12_-_76879852 Show fit	0.72	ENST00000548341.1	OSBPL8 Ensembl NCBI GeneCards UniProt Show fit	oxysterol binding protein-like 8
chr12_-_52685312 Show fit	0.71	ENST00000327741.5	KRT81 Ensembl NCBI GeneCards UniProt Show fit	keratin 81
chr6_-_31619697 Show fit	0.71	ENST00000434444.1	BAG6 Ensembl NCBI GeneCards UniProt Show fit	BCL2-associated athanogene 6
chr17_-_1553346 Show fit	0.71	ENST00000301336.6	RILP Ensembl NCBI GeneCards UniProt Show fit	Rab interacting lysosomal protein
chr1_+_39456895 Show fit	0.71	ENST00000432648.3 ENST00000446189.2 ENST00000372984.4	AKIRIN1 Ensembl NCBI GeneCards UniProt Show fit	akirin 1
chr12_-_51740463 Show fit	0.71	ENST00000293636.1	CELA1 Ensembl NCBI GeneCards UniProt Show fit	chymotrypsin-like elastase family, member 1
chr10_+_94451574 Show fit	0.71	ENST00000492654.2	HHEX Ensembl NCBI GeneCards UniProt Show fit	hematopoietically expressed homeobox
chr17_+_34431212 Show fit	0.71	ENST00000394495.1	CCL4 Ensembl NCBI GeneCards UniProt Show fit	chemokine (C-C motif) ligand 4
chr16_+_57702099 Show fit	0.70	ENST00000333493.4 ENST00000327655.6	GPR97 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 97
chr11_-_85779971 Show fit	0.69	ENST00000393346.3	PICALM Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol binding clathrin assembly protein
chr5_+_95998070 Show fit	0.69	ENST00000421689.2 ENST00000510756.1 ENST00000512620.1	CAST Ensembl NCBI GeneCards UniProt Show fit	calpastatin
chr1_+_10057274 Show fit	0.69	ENST00000294435.7	RBP7 Ensembl NCBI GeneCards UniProt Show fit	retinol binding protein 7, cellular
chr3_-_61237050 Show fit	0.69	ENST00000476844.1 ENST00000488467.1 ENST00000492590.1 ENST00000468189.1	FHIT Ensembl NCBI GeneCards UniProt Show fit	fragile histidine triad
chr7_+_133261209 Show fit	0.68	ENST00000545148.1	EXOC4 Ensembl NCBI GeneCards UniProt Show fit	exocyst complex component 4
chr3_+_171844762 Show fit	0.68	ENST00000443501.1	FNDC3B Ensembl NCBI GeneCards UniProt Show fit	fibronectin type III domain containing 3B
chr17_-_37557846 Show fit	0.67	ENST00000394294.3 ENST00000583610.1 ENST00000264658.6	FBXL20 Ensembl NCBI GeneCards UniProt Show fit	F-box and leucine-rich repeat protein 20
chr12_+_131438496 Show fit	0.67	ENST00000543826.1	GPR133 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 133
chr21_-_16374688 Show fit	0.67	ENST00000411932.1	NRIP1 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor interacting protein 1
chr19_+_859654 Show fit	0.66	ENST00000592860.1	CFD Ensembl NCBI GeneCards UniProt Show fit	complement factor D (adipsin)
chr14_+_23009190 Show fit	0.66	ENST00000390532.1	TRAJ5 Ensembl NCBI GeneCards UniProt Show fit	T cell receptor alpha joining 5
chr14_-_98444369 Show fit	0.66	ENST00000554822.1	C14orf64 Ensembl NCBI GeneCards UniProt Show fit	chromosome 14 open reading frame 64
chr9_+_12695702 Show fit	0.66	ENST00000381136.2	TYRP1 Ensembl NCBI GeneCards UniProt Show fit	tyrosinase-related protein 1
chr19_-_46526304 Show fit	0.66	ENST00000008938.4	PGLYRP1 Ensembl NCBI GeneCards UniProt Show fit	peptidoglycan recognition protein 1
chr20_-_36661826 Show fit	0.65	ENST00000373448.2 ENST00000373447.3	TTI1 Ensembl NCBI GeneCards UniProt Show fit	TELO2 interacting protein 1
chr2_+_201994208 Show fit	0.65	ENST00000440180.1	CFLAR Ensembl NCBI GeneCards UniProt Show fit	CASP8 and FADD-like apoptosis regulator

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX21_TBR1

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.3	3.8	GO:0055073	cadmium ion homeostasis(GO:0055073)
0.8	3.9	GO:0043553	negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.7	4.2	GO:0038112	interleukin-8-mediated signaling pathway(GO:0038112)
0.6	6.2	GO:0002074	extraocular skeletal muscle development(GO:0002074)
0.6	1.8	GO:0060557	positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.6	2.8	GO:0042663	regulation of endodermal cell fate specification(GO:0042663)
0.5	2.6	GO:0032474	otolith morphogenesis(GO:0032474)
0.5	2.0	GO:0002904	positive regulation of B cell apoptotic process(GO:0002904)
0.4	2.2	GO:0051621	negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.4	4.7	GO:0055009	atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.4	1.5	GO:0043376	regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.4	1.8	GO:0046340	diacylglycerol catabolic process(GO:0046340)
0.4	1.8	GO:1902304	positive regulation of potassium ion export(GO:1902304)
0.4	1.1	GO:0035621	ER to Golgi ceramide transport(GO:0035621)
0.3	1.7	GO:0003070	age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.3	1.7	GO:0048388	endosomal lumen acidification(GO:0048388)
0.3	0.8	GO:0019858	cytosine metabolic process(GO:0019858)
0.3	1.9	GO:2000670	positive regulation of dendritic cell apoptotic process(GO:2000670)
0.3	1.4	GO:0060474	positive regulation of sperm motility involved in capacitation(GO:0060474)
0.3	0.8	GO:1904428	negative regulation of tubulin deacetylation(GO:1904428)
0.3	0.8	GO:0032289	central nervous system myelin formation(GO:0032289)
0.3	2.6	GO:1904379	protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.3	0.3	GO:0086092	regulation of the force of heart contraction by cardiac conduction(GO:0086092)
0.2	3.7	GO:0001915	negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.2	0.7	GO:2000523	regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) regulation of dendritic cell dendrite assembly(GO:2000547)
0.2	1.0	GO:0051541	elastin metabolic process(GO:0051541)
0.2	2.2	GO:0001661	conditioned taste aversion(GO:0001661)
0.2	0.7	GO:0070676	intralumenal vesicle formation(GO:0070676)
0.2	0.7	GO:0061010	gall bladder development(GO:0061010)
0.2	1.1	GO:1904845	response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.2	0.9	GO:0003330	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.2	0.7	GO:0001543	ovarian follicle rupture(GO:0001543)
0.2	0.7	GO:0043438	acetoacetic acid metabolic process(GO:0043438)
0.2	0.7	GO:0051714	negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827) positive regulation of cytolysis in other organism(GO:0051714)
0.2	7.1	GO:0045954	positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.2	0.6	GO:0003163	sinoatrial node development(GO:0003163) sinoatrial node cell differentiation(GO:0060921) sinoatrial node cell development(GO:0060931)
0.2	2.7	GO:0019896	axonal transport of mitochondrion(GO:0019896)
0.2	0.5	GO:0045082	positive regulation of interleukin-10 biosynthetic process(GO:0045082) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.2	2.8	GO:0019227	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.2	1.5	GO:1990034	cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.2	0.3	GO:0010387	COP9 signalosome assembly(GO:0010387)
0.2	1.8	GO:0098735	positive regulation of the force of heart contraction(GO:0098735)
0.2	0.9	GO:1990523	bone regeneration(GO:1990523)
0.2	1.7	GO:2000334	blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.2	1.8	GO:0048003	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.1	1.2	GO:0038195	urokinase plasminogen activator signaling pathway(GO:0038195)
0.1	1.0	GO:0035879	plasma membrane lactate transport(GO:0035879)
0.1	0.8	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
0.1	0.4	GO:0006429	glutaminyl-tRNA aminoacylation(GO:0006425) leucyl-tRNA aminoacylation(GO:0006429)
0.1	0.5	GO:1902310	positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1	3.3	GO:0060213	regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.1	1.1	GO:1901295	positive regulation of ephrin receptor signaling pathway(GO:1901189) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1	1.6	GO:1903943	regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1	0.4	GO:1901340	negative regulation of store-operated calcium channel activity(GO:1901340)
0.1	1.6	GO:0002051	osteoblast fate commitment(GO:0002051)
0.1	0.5	GO:0071288	cellular response to mercury ion(GO:0071288) positive regulation of mononuclear cell migration(GO:0071677) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.1	1.3	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1	0.9	GO:0070537	histone H2A K63-linked deubiquitination(GO:0070537)
0.1	0.8	GO:0003172	primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.1	0.5	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.1	0.6	GO:0032571	response to vitamin K(GO:0032571)
0.1	0.7	GO:0021633	optic nerve structural organization(GO:0021633)
0.1	0.3	GO:0035522	monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1	0.9	GO:0007296	vitellogenesis(GO:0007296)
0.1	0.3	GO:0046878	positive regulation of saliva secretion(GO:0046878)
0.1	0.9	GO:1903826	arginine transmembrane transport(GO:1903826)
0.1	0.7	GO:2000503	positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1	0.7	GO:1902962	regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1	1.5	GO:0035630	bone mineralization involved in bone maturation(GO:0035630)
0.1	0.8	GO:2000852	corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.1	0.5	GO:0090403	oxidative stress-induced premature senescence(GO:0090403)
0.1	1.4	GO:0021860	pyramidal neuron development(GO:0021860)
0.1	0.1	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.1	0.8	GO:0090309	positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1	1.2	GO:0030091	protein repair(GO:0030091)
0.1	0.6	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
0.1	1.5	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.1	0.4	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) positive regulation of interleukin-12 secretion(GO:2001184)
0.1	0.4	GO:0009107	lipoate biosynthetic process(GO:0009107)
0.1	0.8	GO:0090385	phagosome-lysosome fusion(GO:0090385)
0.1	0.3	GO:0070433	negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.1	0.2	GO:0048633	positive regulation of skeletal muscle tissue growth(GO:0048633)
0.1	1.0	GO:0031118	rRNA pseudouridine synthesis(GO:0031118)
0.1	0.2	GO:0048925	lateral line system development(GO:0048925)
0.1	0.9	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.1	0.3	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.1	0.4	GO:2000171	negative regulation of dendrite development(GO:2000171)
0.1	1.6	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1	7.0	GO:0000186	activation of MAPKK activity(GO:0000186)
0.1	0.1	GO:0015966	diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
0.1	0.2	GO:0032877	positive regulation of DNA endoreduplication(GO:0032877)
0.1	0.5	GO:2000158	positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1	0.3	GO:0098907	protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907)
0.1	0.3	GO:0046504	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.1	0.2	GO:0050760	negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1	1.0	GO:0044351	macropinocytosis(GO:0044351)
0.1	0.3	GO:2001160	regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.1	0.4	GO:0044861	protein transport into plasma membrane raft(GO:0044861)
0.1	0.5	GO:1903593	regulation of histamine secretion by mast cell(GO:1903593)
0.1	0.4	GO:0048239	negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.1	0.3	GO:0098905	regulation of bundle of His cell action potential(GO:0098905)
0.1	1.8	GO:0048934	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1	0.7	GO:0090204	protein localization to nuclear pore(GO:0090204)
0.1	0.5	GO:0003415	chondrocyte hypertrophy(GO:0003415)
0.1	0.9	GO:0039536	negative regulation of RIG-I signaling pathway(GO:0039536)
0.1	0.3	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.1	1.1	GO:0097264	self proteolysis(GO:0097264)
0.1	0.3	GO:0010760	negative regulation of macrophage chemotaxis(GO:0010760)
0.1	1.0	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.1	0.3	GO:0033326	cerebrospinal fluid secretion(GO:0033326)
0.1	1.3	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.1	0.2	GO:0061433	cellular response to caloric restriction(GO:0061433) negative regulation of oligodendrocyte progenitor proliferation(GO:0070446)
0.1	0.6	GO:1902302	regulation of potassium ion export(GO:1902302)
0.1	0.6	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.1	0.7	GO:0032688	negative regulation of interferon-beta production(GO:0032688)
0.1	1.0	GO:2000786	positive regulation of autophagosome assembly(GO:2000786)
0.1	0.8	GO:0030299	intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.1	0.9	GO:0015884	folic acid transport(GO:0015884)
0.1	1.9	GO:0043153	entrainment of circadian clock by photoperiod(GO:0043153)
0.0	0.3	GO:0042986	positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0	0.5	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	1.4	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.1	GO:0014908	myotube differentiation involved in skeletal muscle regeneration(GO:0014908)
0.0	0.5	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.0	0.6	GO:0002710	negative regulation of T cell mediated immunity(GO:0002710)
0.0	2.3	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.4	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0	0.5	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	1.0	GO:0007220	Notch receptor processing(GO:0007220)
0.0	7.7	GO:0046718	viral entry into host cell(GO:0046718)
0.0	0.4	GO:0018344	protein geranylgeranylation(GO:0018344)
0.0	0.3	GO:1903588	negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0	0.4	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	0.7	GO:0048341	paraxial mesoderm formation(GO:0048341)
0.0	0.4	GO:0040032	post-embryonic body morphogenesis(GO:0040032)
0.0	1.6	GO:0097186	amelogenesis(GO:0097186)
0.0	0.6	GO:0002227	innate immune response in mucosa(GO:0002227)
0.0	0.2	GO:0071596	ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0	0.2	GO:0036353	histone H2A-K119 monoubiquitination(GO:0036353)
0.0	0.3	GO:0010793	regulation of mRNA export from nucleus(GO:0010793)
0.0	0.3	GO:2001205	negative regulation of osteoclast development(GO:2001205)
0.0	0.5	GO:2000210	positive regulation of anoikis(GO:2000210)
0.0	0.2	GO:0060268	negative regulation of respiratory burst(GO:0060268)
0.0	0.4	GO:1901098	positive regulation of autophagosome maturation(GO:1901098)
0.0	0.4	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
0.0	0.2	GO:1902775	mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0	0.5	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.0	0.9	GO:0071361	cellular response to ethanol(GO:0071361)
0.0	0.7	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0	0.3	GO:0009644	response to high light intensity(GO:0009644)
0.0	0.4	GO:0045075	interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0	0.3	GO:0061366	negative regulation of growth hormone secretion(GO:0060125) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0	2.0	GO:1900078	positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0	0.3	GO:0019262	N-acetylneuraminate catabolic process(GO:0019262)
0.0	0.3	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	0.3	GO:0070475	rRNA base methylation(GO:0070475)
0.0	0.4	GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.0	1.1	GO:0006337	nucleosome disassembly(GO:0006337)
0.0	0.7	GO:0072378	blood coagulation, fibrin clot formation(GO:0072378)
0.0	1.6	GO:0035411	catenin import into nucleus(GO:0035411)
0.0	0.2	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.0	0.5	GO:0001955	blood vessel maturation(GO:0001955)
0.0	0.8	GO:0097067	cellular response to thyroid hormone stimulus(GO:0097067)
0.0	0.1	GO:0009213	pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.0	0.2	GO:0098989	NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0	0.9	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	4.6	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0	0.2	GO:0000160	phosphorelay signal transduction system(GO:0000160)
0.0	0.7	GO:0006839	mitochondrial transport(GO:0006839)
0.0	0.1	GO:0018057	peptidyl-lysine oxidation(GO:0018057)
0.0	2.1	GO:0045652	regulation of megakaryocyte differentiation(GO:0045652)
0.0	0.3	GO:0048875	chemical homeostasis within a tissue(GO:0048875)
0.0	0.1	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0	0.6	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.9	GO:0042276	error-prone translesion synthesis(GO:0042276)
0.0	0.4	GO:0098828	positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0	1.1	GO:1904659	hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0	0.9	GO:0006677	glycosylceramide metabolic process(GO:0006677)
0.0	2.3	GO:0007602	phototransduction(GO:0007602)
0.0	0.2	GO:0035095	behavioral response to nicotine(GO:0035095)
0.0	0.3	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0	0.1	GO:0070884	regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0	0.5	GO:0060134	prepulse inhibition(GO:0060134)
0.0	0.2	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0	0.4	GO:0090527	actin filament reorganization(GO:0090527)
0.0	0.2	GO:0072513	positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0	0.4	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
0.0	0.6	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.0	0.1	GO:0070092	regulation of glucagon secretion(GO:0070092)
0.0	0.5	GO:0008228	opsonization(GO:0008228)
0.0	1.0	GO:0019228	neuronal action potential(GO:0019228)
0.0	0.3	GO:0002820	negative regulation of adaptive immune response(GO:0002820)
0.0	0.7	GO:0006590	thyroid hormone generation(GO:0006590)
0.0	0.2	GO:0034551	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0	1.3	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.0	1.5	GO:0014047	glutamate secretion(GO:0014047)
0.0	1.1	GO:0030101	natural killer cell activation(GO:0030101)
0.0	0.6	GO:0030033	microvillus assembly(GO:0030033)
0.0	0.1	GO:0001207	histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.0	1.7	GO:0033275	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0	0.3	GO:1904903	ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0	0.2	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.3	GO:0051828	entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.0	0.1	GO:0035803	egg coat formation(GO:0035803)
0.0	0.4	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.9	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.3	GO:2000001	regulation of DNA damage checkpoint(GO:2000001)
0.0	0.2	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.2	GO:0000722	telomere maintenance via recombination(GO:0000722)
0.0	0.4	GO:2000398	regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.0	0.3	GO:0010944	negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0	1.7	GO:0038083	peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0	0.1	GO:1901096	regulation of autophagosome maturation(GO:1901096)
0.0	0.2	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.9	GO:0042267	natural killer cell mediated cytotoxicity(GO:0042267)
0.0	0.4	GO:0007096	regulation of exit from mitosis(GO:0007096)
0.0	0.3	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.0	0.2	GO:0072520	seminiferous tubule development(GO:0072520)
0.0	1.2	GO:0021762	substantia nigra development(GO:0021762)
0.0	1.1	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0	0.2	GO:0034472	snRNA 3'-end processing(GO:0034472)
0.0	0.6	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.0	0.6	GO:0032006	regulation of TOR signaling(GO:0032006)
0.0	1.3	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.4	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0	0.2	GO:1904893	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	1.9	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0	0.0	GO:1990502	dense core granule maturation(GO:1990502)
0.0	1.1	GO:0006672	ceramide metabolic process(GO:0006672)
0.0	0.0	GO:2000110	negative regulation of macrophage apoptotic process(GO:2000110)
0.0	0.1	GO:0006404	RNA import into nucleus(GO:0006404) snRNA import into nucleus(GO:0061015)
0.0	0.2	GO:0060716	labyrinthine layer blood vessel development(GO:0060716)
0.0	0.3	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.2	GO:0010592	positive regulation of lamellipodium assembly(GO:0010592)
0.0	0.5	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0	0.1	GO:0042256	mature ribosome assembly(GO:0042256)
0.0	1.4	GO:0048010	vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0	0.8	GO:0045773	positive regulation of axon extension(GO:0045773)
0.0	0.5	GO:0002209	behavioral fear response(GO:0001662) behavioral defense response(GO:0002209)
0.0	0.1	GO:0072402	response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
0.0	0.9	GO:1901799	negative regulation of proteasomal protein catabolic process(GO:1901799)
0.0	0.7	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.0	0.1	GO:0032508	DNA duplex unwinding(GO:0032508)
0.0	0.2	GO:0043248	proteasome assembly(GO:0043248)
0.0	0.1	GO:0000920	cell separation after cytokinesis(GO:0000920)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	10.8	GO:0032982	myosin filament(GO:0032982)
0.3	3.0	GO:0005955	calcineurin complex(GO:0005955)
0.2	1.4	GO:0097441	basilar dendrite(GO:0097441)
0.2	2.6	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.2	1.9	GO:0035976	AP1 complex(GO:0035976)
0.2	1.8	GO:0043196	varicosity(GO:0043196)
0.2	1.6	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
0.2	0.8	GO:0035354	Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.1	6.3	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.1	0.5	GO:0005889	hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.1	2.0	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.1	0.7	GO:0070381	endosome to plasma membrane transport vesicle(GO:0070381)
0.1	1.1	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1	1.4	GO:0097524	sperm plasma membrane(GO:0097524)
0.1	0.5	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1	1.1	GO:0070765	gamma-secretase complex(GO:0070765)
0.1	0.4	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1	0.2	GO:0036194	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1	1.7	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.1	0.6	GO:0034688	integrin alphaM-beta2 complex(GO:0034688)
0.1	0.5	GO:0097013	phagocytic vesicle lumen(GO:0097013)
0.1	3.3	GO:0042629	mast cell granule(GO:0042629)
0.1	0.9	GO:0070531	BRCA1-A complex(GO:0070531)
0.1	0.1	GO:0005683	U7 snRNP(GO:0005683)
0.1	1.6	GO:0031265	CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.1	1.2	GO:0071438	invadopodium membrane(GO:0071438)
0.1	1.6	GO:0032591	dendritic spine membrane(GO:0032591)
0.1	0.7	GO:0032584	growth cone membrane(GO:0032584)
0.1	1.1	GO:0043020	NADPH oxidase complex(GO:0043020)
0.1	4.5	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.1	0.8	GO:0030427	site of polarized growth(GO:0030427)
0.1	1.1	GO:0060077	inhibitory synapse(GO:0060077)
0.0	0.4	GO:0031415	NatA complex(GO:0031415)
0.0	0.8	GO:0033010	paranodal junction(GO:0033010)
0.0	5.0	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	1.6	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.7	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.2	GO:0001405	presequence translocase-associated import motor(GO:0001405)
0.0	0.4	GO:0044352	pinosome(GO:0044352) macropinosome(GO:0044354)
0.0	1.5	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.0	4.2	GO:0034707	chloride channel complex(GO:0034707)
0.0	0.4	GO:0043219	lateral loop(GO:0043219)
0.0	0.3	GO:0043194	axon initial segment(GO:0043194)
0.0	1.0	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.0	0.9	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0	0.5	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	2.8	GO:1904115	axon cytoplasm(GO:1904115)
0.0	2.0	GO:0071339	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	0.7	GO:0045009	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0	0.2	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.0	0.5	GO:0000788	nuclear nucleosome(GO:0000788)
0.0	0.2	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.0	0.8	GO:0005859	muscle myosin complex(GO:0005859)
0.0	2.4	GO:0045171	intercellular bridge(GO:0045171)
0.0	0.2	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.2	GO:0097255	R2TP complex(GO:0097255)
0.0	0.3	GO:0098839	postsynaptic density membrane(GO:0098839)
0.0	0.4	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.2	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	0.1	GO:1902937	inward rectifier potassium channel complex(GO:1902937)
0.0	0.4	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.0	0.9	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.0	0.5	GO:0017119	Golgi transport complex(GO:0017119)
0.0	3.8	GO:0035579	specific granule membrane(GO:0035579)
0.0	2.4	GO:0014704	intercalated disc(GO:0014704)
0.0	10.4	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	1.9	GO:0016459	myosin complex(GO:0016459)
0.0	0.1	GO:0031510	SUMO activating enzyme complex(GO:0031510)
0.0	0.2	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.4	GO:0070938	contractile ring(GO:0070938)
0.0	0.6	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.2	GO:0001652	granular component(GO:0001652)
0.0	0.1	GO:0005668	RNA polymerase transcription factor SL1 complex(GO:0005668)
0.0	0.3	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	0.2	GO:1990812	growth cone filopodium(GO:1990812)
0.0	0.3	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	1.1	GO:0000786	nucleosome(GO:0000786)
0.0	0.1	GO:0035101	FACT complex(GO:0035101)
0.0	0.2	GO:0045179	apical cortex(GO:0045179)
0.0	1.4	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	2.5	GO:0005776	autophagosome(GO:0005776)
0.0	0.1	GO:0016589	NURF complex(GO:0016589)
0.0	0.6	GO:0070822	Sin3-type complex(GO:0070822)
0.0	0.4	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.6	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.3	GO:0005687	U4 snRNP(GO:0005687)
0.0	3.8	GO:1904813	ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0	4.5	GO:0005802	trans-Golgi network(GO:0005802)
0.0	0.9	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.6	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0	0.2	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.0	2.4	GO:0032587	ruffle membrane(GO:0032587)
0.0	3.3	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0	0.2	GO:0032039	integrator complex(GO:0032039)
0.0	1.8	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	0.2	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.0	1.0	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.1	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0	0.7	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	0.8	GO:0031983	vesicle lumen(GO:0031983) cytoplasmic membrane-bounded vesicle lumen(GO:0060205)
0.0	0.2	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.3	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.3	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.2	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.0	0.4	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.1	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.1	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.1	GO:0001939	female pronucleus(GO:0001939) male pronucleus(GO:0001940)
0.0	2.9	GO:0030667	secretory granule membrane(GO:0030667)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.6	6.6	GO:0050528	acyloxyacyl hydrolase activity(GO:0050528)
1.3	3.9	GO:0036313	phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
1.3	3.8	GO:0051139	metal ion:proton antiporter activity(GO:0051139)
0.7	4.2	GO:0004918	interleukin-8 receptor activity(GO:0004918)
0.6	5.3	GO:0017018	myosin phosphatase activity(GO:0017018)
0.4	2.2	GO:0060961	phospholipase D inhibitor activity(GO:0060961)
0.4	2.0	GO:0070051	fibrinogen binding(GO:0070051)
0.3	2.3	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.3	1.6	GO:0051916	granulocyte colony-stimulating factor binding(GO:0051916)
0.3	1.8	GO:0099580	ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.2	0.5	GO:0005136	interleukin-4 receptor binding(GO:0005136)
0.2	1.0	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.2	2.2	GO:0042610	CD8 receptor binding(GO:0042610)
0.2	1.1	GO:0051373	FATZ binding(GO:0051373)
0.2	2.9	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.2	1.7	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2	0.6	GO:0047696	beta-adrenergic receptor kinase activity(GO:0047696)
0.2	6.2	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.2	1.8	GO:0030883	lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.2	1.1	GO:0097001	ceramide binding(GO:0097001)
0.2	1.2	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.2	1.2	GO:0030377	urokinase plasminogen activator receptor activity(GO:0030377)
0.2	1.7	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.2	0.7	GO:0016716	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.2	0.7	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.2	0.6	GO:0004917	interleukin-7 receptor activity(GO:0004917)
0.2	7.0	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.2	1.7	GO:0070892	lipoteichoic acid receptor activity(GO:0070892)
0.1	0.9	GO:0030109	HLA-B specific inhibitory MHC class I receptor activity(GO:0030109)
0.1	0.4	GO:0004823	glutamine-tRNA ligase activity(GO:0004819) leucine-tRNA ligase activity(GO:0004823)
0.1	0.9	GO:0047493	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1	0.7	GO:0039552	RIG-I binding(GO:0039552)
0.1	2.1	GO:0019957	C-C chemokine binding(GO:0019957)
0.1	0.5	GO:0048030	disaccharide binding(GO:0048030)
0.1	1.4	GO:0031697	beta-1 adrenergic receptor binding(GO:0031697)
0.1	0.5	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.1	2.3	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1	0.8	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.1	3.1	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.1	1.8	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.1	0.7	GO:0031726	CCR1 chemokine receptor binding(GO:0031726)
0.1	0.3	GO:0004772	sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.1	0.8	GO:0071723	lipopeptide binding(GO:0071723)
0.1	0.8	GO:0004126	cytidine deaminase activity(GO:0004126)
0.1	0.9	GO:0015181	arginine transmembrane transporter activity(GO:0015181)
0.1	0.9	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1	2.2	GO:0015643	toxic substance binding(GO:0015643)
0.1	2.7	GO:0050811	GABA receptor binding(GO:0050811)
0.1	1.5	GO:0003796	lysozyme activity(GO:0003796)
0.1	0.2	GO:0031433	telethonin binding(GO:0031433)
0.1	0.2	GO:0016532	superoxide dismutase copper chaperone activity(GO:0016532)
0.1	0.8	GO:0008307	structural constituent of muscle(GO:0008307)
0.1	0.5	GO:0004647	phosphoserine phosphatase activity(GO:0004647)
0.1	9.0	GO:0001618	virus receptor activity(GO:0001618)
0.1	1.1	GO:0004896	cytokine receptor activity(GO:0004896)
0.1	0.5	GO:0004447	iodide peroxidase activity(GO:0004447)
0.1	0.5	GO:0035800	deubiquitinase activator activity(GO:0035800)
0.1	3.0	GO:0005123	death receptor binding(GO:0005123)
0.1	0.2	GO:0010698	acetyltransferase activator activity(GO:0010698)
0.1	2.1	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.1	0.7	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1	0.6	GO:0001851	complement component C3b binding(GO:0001851)
0.1	0.8	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1	0.5	GO:0017040	ceramidase activity(GO:0017040)
0.1	0.5	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.1	0.4	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1	0.7	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.1	0.3	GO:0016434	rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1	1.5	GO:0008494	translation activator activity(GO:0008494)
0.1	4.6	GO:0019843	rRNA binding(GO:0019843)
0.1	1.1	GO:0000150	recombinase activity(GO:0000150)
0.1	1.4	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1	0.3	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.1	0.2	GO:0046970	NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0	0.8	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	1.5	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	1.1	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.0	0.4	GO:0001594	trace-amine receptor activity(GO:0001594)
0.0	7.5	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.1	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.0	1.1	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.5	GO:1904315	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0	1.5	GO:0071837	HMG box domain binding(GO:0071837)
0.0	1.5	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	1.3	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	2.8	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	1.0	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0	2.4	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	0.9	GO:0005542	folic acid binding(GO:0005542)
0.0	2.8	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.8	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.0	0.3	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.0	0.4	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.0	0.2	GO:0070728	leucine binding(GO:0070728)
0.0	0.2	GO:0047685	amine sulfotransferase activity(GO:0047685)
0.0	1.2	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.9	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.7	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.0	1.6	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.3	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.0	0.2	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.1	GO:0071209	U7 snRNA binding(GO:0071209)
0.0	0.4	GO:0051525	NFAT protein binding(GO:0051525)
0.0	1.4	GO:0005521	lamin binding(GO:0005521)
0.0	0.4	GO:0097016	L27 domain binding(GO:0097016)
0.0	0.3	GO:0033857	diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0	0.2	GO:0034061	DNA polymerase activity(GO:0034061)
0.0	1.5	GO:0005227	calcium activated cation channel activity(GO:0005227)
0.0	0.5	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.0	0.2	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.0	1.0	GO:0005248	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	0.1	GO:0004711	ribosomal protein S6 kinase activity(GO:0004711)
0.0	1.1	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.0	0.9	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.5	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.5	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.0	0.3	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.9	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.6	GO:0022848	acetylcholine-gated cation channel activity(GO:0022848)
0.0	0.8	GO:0004806	triglyceride lipase activity(GO:0004806)
0.0	1.0	GO:0070888	E-box binding(GO:0070888)
0.0	2.3	GO:0016279	protein-lysine N-methyltransferase activity(GO:0016279)
0.0	0.9	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.0	0.4	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	1.1	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.7	GO:0017160	Ral GTPase binding(GO:0017160)
0.0	0.2	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.1	GO:0036033	mediator complex binding(GO:0036033)
0.0	0.4	GO:0098505	G-rich strand telomeric DNA binding(GO:0098505)
0.0	0.1	GO:0034041	sterol-transporting ATPase activity(GO:0034041)
0.0	0.2	GO:0004305	ethanolamine kinase activity(GO:0004305)
0.0	0.9	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.7	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.6	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.0	1.0	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.0	0.1	GO:0070628	proteasome binding(GO:0070628)
0.0	0.2	GO:0008308	voltage-gated anion channel activity(GO:0008308)
0.0	0.1	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0	0.7	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.1	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.0	0.4	GO:0070403	NAD+ binding(GO:0070403)
0.0	0.7	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.0	0.2	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.1	GO:0032552	deoxyribonucleotide binding(GO:0032552)
0.0	0.5	GO:0030275	LRR domain binding(GO:0030275)
0.0	0.2	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.4	GO:0019841	retinol binding(GO:0019841)
0.0	0.2	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.6	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.6	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.6	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	0.5	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0	0.1	GO:0003947	(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity(GO:0003947)
0.0	0.3	GO:0051400	BH domain binding(GO:0051400)
0.0	0.4	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.4	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.2	GO:0038062	protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0	0.1	GO:0015217	ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0	0.2	GO:0048156	tau protein binding(GO:0048156)
0.0	0.6	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	0.9	GO:0043130	ubiquitin binding(GO:0043130)
0.0	0.5	GO:0051393	alpha-actinin binding(GO:0051393)
0.0	0.4	GO:0042169	SH2 domain binding(GO:0042169)
0.0	1.3	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0	0.1	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
0.0	0.1	GO:0032027	myosin light chain binding(GO:0032027)
0.0	0.3	GO:0070016	armadillo repeat domain binding(GO:0070016)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	7.9	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.1	4.2	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.1	11.4	PID FGF PATHWAY	FGF signaling pathway
0.1	0.9	PID IL1 PATHWAY	IL1-mediated signaling events
0.1	2.7	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.1	2.4	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.1	2.0	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.1	1.3	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.1	2.9	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.1	1.6	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.1	0.9	ST G ALPHA S PATHWAY	G alpha s Pathway
0.1	4.6	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	1.6	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.9	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.5	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	1.8	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.9	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	1.0	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	3.3	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	2.0	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	3.1	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	1.1	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	1.4	PID AP1 PATHWAY	AP-1 transcription factor network
0.0	0.9	PID INSULIN PATHWAY	Insulin Pathway
0.0	0.2	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.8	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.8	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	1.1	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.9	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.3	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	1.5	PID FOXO PATHWAY	FoxO family signaling
0.0	2.5	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	0.7	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	1.3	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	2.4	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.7	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	0.4	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	0.4	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	4.2	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.0	0.3	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.6	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.9	PID ATM PATHWAY	ATM pathway
0.0	0.5	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	0.5	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	1.8	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	0.3	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	1.5	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.0	1.1	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	0.5	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.0	0.8	PID AURORA B PATHWAY	Aurora B signaling
0.0	0.1	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	11.6	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.1	2.9	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.1	2.2	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.1	2.3	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	4.8	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1	3.0	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	3.3	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.1	6.2	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.1	1.3	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	0.9	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.1	3.5	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1	1.8	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.1	2.3	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.1	0.8	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.1	1.1	REACTOME SIGNALING BY NOTCH3	Genes involved in Signaling by NOTCH3
0.1	1.6	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.1	3.1	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.1	4.2	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.1	6.0	REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S	Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.0	0.8	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	0.2	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	1.3	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	3.2	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	2.5	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	2.2	REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	Genes involved in Glucagon signaling in metabolic regulation
0.0	1.0	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	1.9	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	1.0	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	1.5	REACTOME CD28 CO STIMULATION	Genes involved in CD28 co-stimulation
0.0	0.6	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	3.6	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.7	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	2.8	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.5	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	0.7	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.4	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.4	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.5	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	3.5	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	1.5	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.9	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.9	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.8	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	1.0	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.6	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.0	0.3	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0	1.0	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.8	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.6	REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS	Genes involved in Post NMDA receptor activation events
0.0	0.6	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.3	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.9	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	1.0	REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE	Genes involved in MyD88:Mal cascade initiated on plasma membrane
0.0	0.2	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.5	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	1.5	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0	0.4	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.7	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer

Results for TBX21_TBR1

Z-value: 1.52

Motif logo

Transcription factors associated with TBX21_TBR1

Activity-expression correlation:

Activity profile of TBX21_TBR1 motif

Sorted Z-values of TBX21_TBR1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX21_TBR1

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: