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Illumina Body Map 2: averaged replicates

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Results for TBX4

Z-value: 0.95

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Transcription factors associated with TBX4

Gene Symbol Gene ID Gene Info
TBX4
ENSG00000121075.5 T-box transcription factor 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX4hg19_v2_chr17_+_59529743_59529798-0.154.0e-01Click!

Activity profile of TBX4 motif

Sorted Z-values of TBX4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_143013198 2.33 ENST00000343257.2
CLCN1
chloride channel, voltage-sensitive 1
chr21_+_30503282 2.30 ENST00000399925.1
MAP3K7CL
MAP3K7 C-terminal like
chr21_+_30502806 2.10 ENST00000399928.1
ENST00000399926.1
MAP3K7CL
MAP3K7 C-terminal like
chr2_+_7865923 2.07 ENST00000417930.1
AC092580.4
AC092580.4
chr6_-_130536774 1.70 ENST00000532763.1
SAMD3
sterile alpha motif domain containing 3
chr2_+_219472637 1.47 ENST00000417849.1
PLCD4
phospholipase C, delta 4
chr2_+_219472488 1.31 ENST00000450993.2
PLCD4
phospholipase C, delta 4
chrX_+_123480194 1.27 ENST00000371139.4
SH2D1A
SH2 domain containing 1A
chr14_+_75746664 1.22 ENST00000557139.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr1_+_154378049 1.21 ENST00000512471.1
IL6R
interleukin 6 receptor
chr18_-_56296182 1.15 ENST00000361673.3
ALPK2
alpha-kinase 2
chr1_+_154377669 1.09 ENST00000368485.3
ENST00000344086.4
IL6R
interleukin 6 receptor
chr5_+_54320078 1.09 ENST00000231009.2
GZMK
granzyme K (granzyme 3; tryptase II)
chrX_+_123480375 1.07 ENST00000360027.4
SH2D1A
SH2 domain containing 1A
chr14_+_98602380 1.05 ENST00000557072.1
RP11-61O1.2
RP11-61O1.2
chr5_-_114515734 1.04 ENST00000514154.1
ENST00000282369.3
TRIM36
tripartite motif containing 36
chr1_+_158325684 1.03 ENST00000368162.2
CD1E
CD1e molecule
chr10_-_75226166 1.01 ENST00000544628.1
PPP3CB
protein phosphatase 3, catalytic subunit, beta isozyme
chr10_+_45406627 0.99 ENST00000389583.4
TMEM72
transmembrane protein 72
chr1_+_228395755 0.99 ENST00000284548.11
ENST00000570156.2
ENST00000422127.1
ENST00000366707.4
ENST00000366709.4
OBSCN
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chrX_+_123480421 0.98 ENST00000477673.2
SH2D1A
SH2 domain containing 1A
chr11_+_122709200 0.97 ENST00000227348.4
CRTAM
cytotoxic and regulatory T cell molecule
chr10_+_45406764 0.97 ENST00000544540.1
TMEM72
transmembrane protein 72
chr11_-_33913708 0.94 ENST00000257818.2
LMO2
LIM domain only 2 (rhombotin-like 1)
chr2_-_61697862 0.88 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr12_-_65090329 0.88 ENST00000594966.1
AC025262.1
Mesenchymal stem cell protein DSC96; Uncharacterized protein
chr1_+_206680879 0.88 ENST00000355294.4
ENST00000367117.3
RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr15_-_38852251 0.87 ENST00000558432.1
RASGRP1
RAS guanyl releasing protein 1 (calcium and DAG-regulated)
chr2_-_25475120 0.76 ENST00000380746.4
ENST00000402667.1
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr5_-_74807418 0.75 ENST00000405807.4
ENST00000261415.7
COL4A3BP
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
chr22_+_40441456 0.75 ENST00000402203.1
TNRC6B
trinucleotide repeat containing 6B
chr10_-_16563870 0.74 ENST00000298943.3
C1QL3
complement component 1, q subcomponent-like 3
chr9_-_117692697 0.71 ENST00000223795.2
TNFSF8
tumor necrosis factor (ligand) superfamily, member 8
chr12_+_65672702 0.70 ENST00000538045.1
ENST00000535239.1
MSRB3
methionine sulfoxide reductase B3
chr1_-_205290865 0.70 ENST00000367157.3
NUAK2
NUAK family, SNF1-like kinase, 2
chr3_+_134514093 0.68 ENST00000398015.3
EPHB1
EPH receptor B1
chr17_-_37557846 0.67 ENST00000394294.3
ENST00000583610.1
ENST00000264658.6
FBXL20
F-box and leucine-rich repeat protein 20
chr7_+_133261209 0.67 ENST00000545148.1
EXOC4
exocyst complex component 4
chr8_+_123793633 0.67 ENST00000314393.4
ZHX2
zinc fingers and homeoboxes 2
chr5_+_82767284 0.65 ENST00000265077.3
VCAN
versican
chr7_-_27142290 0.64 ENST00000222718.5
HOXA2
homeobox A2
chr12_-_116714564 0.64 ENST00000548743.1
MED13L
mediator complex subunit 13-like
chr4_-_41749724 0.64 ENST00000510424.1
PHOX2B
paired-like homeobox 2b
chr5_+_82767487 0.61 ENST00000343200.5
ENST00000342785.4
VCAN
versican
chr11_-_85430356 0.60 ENST00000526999.1
SYTL2
synaptotagmin-like 2
chr15_+_91449971 0.59 ENST00000557865.1
MAN2A2
mannosidase, alpha, class 2A, member 2
chr8_+_22435762 0.59 ENST00000456545.1
PDLIM2
PDZ and LIM domain 2 (mystique)
chr14_+_53196872 0.57 ENST00000442123.2
ENST00000354586.4
STYX
serine/threonine/tyrosine interacting protein
chr15_+_36994210 0.57 ENST00000562489.1
C15orf41
chromosome 15 open reading frame 41
chr12_+_58148842 0.56 ENST00000266643.5
MARCH9
membrane-associated ring finger (C3HC4) 9
chr14_+_75746781 0.56 ENST00000555347.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr5_+_133861339 0.56 ENST00000282605.4
ENST00000361895.2
ENST00000402835.1
PHF15
jade family PHD finger 2
chr12_-_90024360 0.56 ENST00000393164.2
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr1_+_16062820 0.55 ENST00000294454.5
SLC25A34
solute carrier family 25, member 34
chr2_+_61108771 0.55 ENST00000394479.3
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr17_-_7232585 0.54 ENST00000571887.1
ENST00000315614.7
ENST00000399464.2
ENST00000570460.1
NEURL4
neuralized E3 ubiquitin protein ligase 4
chr4_-_102268628 0.53 ENST00000323055.6
ENST00000512215.1
ENST00000394854.3
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr14_+_22955216 0.53 ENST00000390486.1
TRAJ52
T cell receptor alpha joining 52
chr12_+_57853918 0.53 ENST00000532291.1
ENST00000543426.1
ENST00000228682.2
ENST00000546141.1
GLI1
GLI family zinc finger 1
chr15_+_92937144 0.53 ENST00000539113.1
ENST00000555434.1
ST8SIA2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr6_+_167536230 0.52 ENST00000341935.5
ENST00000349984.4
CCR6
chemokine (C-C motif) receptor 6
chr11_+_61447845 0.52 ENST00000257215.5
DAGLA
diacylglycerol lipase, alpha
chr4_-_102268708 0.51 ENST00000525819.1
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr9_+_34990219 0.51 ENST00000541010.1
ENST00000454002.2
ENST00000545841.1
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr5_+_150040403 0.51 ENST00000517768.1
ENST00000297130.4
MYOZ3
myozenin 3
chr1_-_226076843 0.51 ENST00000272134.5
LEFTY1
left-right determination factor 1
chr1_+_172628154 0.50 ENST00000340030.3
ENST00000367721.2
FASLG
Fas ligand (TNF superfamily, member 6)
chr4_-_114438763 0.50 ENST00000509594.1
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr11_+_64073699 0.50 ENST00000405666.1
ENST00000468670.1
ESRRA
estrogen-related receptor alpha
chr9_-_74979420 0.50 ENST00000343431.2
ENST00000376956.3
ZFAND5
zinc finger, AN1-type domain 5
chr14_+_75745477 0.48 ENST00000303562.4
ENST00000554617.1
ENST00000554212.1
ENST00000535987.1
ENST00000555242.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr11_-_34535332 0.48 ENST00000257832.2
ENST00000429939.2
ELF5
E74-like factor 5 (ets domain transcription factor)
chr2_-_40680578 0.48 ENST00000455476.1
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr16_+_85645007 0.47 ENST00000405402.2
GSE1
Gse1 coiled-coil protein
chr14_+_90864504 0.47 ENST00000544280.2
CALM1
calmodulin 1 (phosphorylase kinase, delta)
chr16_-_79263322 0.47 ENST00000569677.1
RP11-679B19.2
RP11-679B19.2
chr10_+_31608054 0.46 ENST00000320985.10
ENST00000361642.5
ENST00000560721.2
ENST00000558440.1
ENST00000424869.1
ENST00000542815.3
ZEB1
zinc finger E-box binding homeobox 1
chr7_-_28220354 0.46 ENST00000283928.5
JAZF1
JAZF zinc finger 1
chr11_-_85430088 0.45 ENST00000533057.1
ENST00000533892.1
SYTL2
synaptotagmin-like 2
chrX_-_19689106 0.45 ENST00000379716.1
SH3KBP1
SH3-domain kinase binding protein 1
chr18_+_32073253 0.45 ENST00000283365.9
ENST00000596745.1
ENST00000315456.6
DTNA
dystrobrevin, alpha
chr8_-_101724989 0.45 ENST00000517403.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr10_-_98945264 0.44 ENST00000314867.5
SLIT1
slit homolog 1 (Drosophila)
chr2_-_111291587 0.44 ENST00000437167.1
RGPD6
RANBP2-like and GRIP domain containing 6
chr11_-_85430204 0.44 ENST00000389958.3
ENST00000527794.1
SYTL2
synaptotagmin-like 2
chr4_+_160188889 0.43 ENST00000264431.4
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chrX_+_47050798 0.43 ENST00000412206.1
ENST00000427561.1
UBA1
ubiquitin-like modifier activating enzyme 1
chr15_+_92937058 0.43 ENST00000268164.3
ST8SIA2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr11_-_85430163 0.43 ENST00000529581.1
ENST00000533577.1
SYTL2
synaptotagmin-like 2
chr4_-_102268484 0.43 ENST00000394853.4
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chrX_+_123095546 0.42 ENST00000371157.3
ENST00000371145.3
ENST00000371144.3
STAG2
stromal antigen 2
chr3_+_167453026 0.42 ENST00000472941.1
SERPINI1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr2_+_29033682 0.41 ENST00000379579.4
ENST00000334056.5
ENST00000449210.1
SPDYA
speedy/RINGO cell cycle regulator family member A
chr1_+_26737292 0.40 ENST00000254231.4
LIN28A
lin-28 homolog A (C. elegans)
chr12_+_57854274 0.40 ENST00000528432.1
GLI1
GLI family zinc finger 1
chr7_+_27282319 0.39 ENST00000222761.3
EVX1
even-skipped homeobox 1
chrX_+_123095890 0.39 ENST00000435215.1
STAG2
stromal antigen 2
chr17_-_61973929 0.38 ENST00000329882.8
ENST00000453363.3
ENST00000316193.8
CSH1
chorionic somatomammotropin hormone 1 (placental lactogen)
chr17_-_61996160 0.38 ENST00000458650.2
ENST00000351388.4
ENST00000323322.5
GH1
growth hormone 1
chr10_+_7860460 0.38 ENST00000344293.5
TAF3
TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa
chr17_-_39222131 0.38 ENST00000394015.2
KRTAP2-4
keratin associated protein 2-4
chr7_-_105319536 0.37 ENST00000477775.1
ATXN7L1
ataxin 7-like 1
chr15_-_83474806 0.37 ENST00000541889.1
ENST00000334574.8
ENST00000561368.1
FSD2
fibronectin type III and SPRY domain containing 2
chr4_+_140222609 0.37 ENST00000296543.5
ENST00000398947.1
NAA15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr11_-_33891362 0.36 ENST00000395833.3
LMO2
LIM domain only 2 (rhombotin-like 1)
chr12_+_18891045 0.36 ENST00000317658.3
CAPZA3
capping protein (actin filament) muscle Z-line, alpha 3
chr8_+_56014949 0.36 ENST00000327381.6
XKR4
XK, Kell blood group complex subunit-related family, member 4
chr17_-_61996192 0.36 ENST00000392824.4
CSHL1
chorionic somatomammotropin hormone-like 1
chr11_-_128737163 0.36 ENST00000324003.3
ENST00000392665.2
KCNJ1
potassium inwardly-rectifying channel, subfamily J, member 1
chr19_+_10131437 0.35 ENST00000587782.1
RDH8
retinol dehydrogenase 8 (all-trans)
chr5_-_88180342 0.35 ENST00000502983.1
MEF2C
myocyte enhancer factor 2C
chr18_+_32073839 0.35 ENST00000590412.1
DTNA
dystrobrevin, alpha
chr12_-_91348949 0.34 ENST00000358859.2
CCER1
coiled-coil glutamate-rich protein 1
chr2_+_103089756 0.34 ENST00000295269.4
SLC9A4
solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4
chr2_+_17997763 0.34 ENST00000281047.3
MSGN1
mesogenin 1
chr1_+_114471809 0.34 ENST00000426820.2
HIPK1
homeodomain interacting protein kinase 1
chr22_-_42342733 0.33 ENST00000402420.1
CENPM
centromere protein M
chr2_-_177684007 0.33 ENST00000451851.1
AC092162.1
AC092162.1
chr16_+_2587998 0.33 ENST00000441549.3
ENST00000268673.7
PDPK1
3-phosphoinositide dependent protein kinase-1
chrX_+_123095860 0.33 ENST00000428941.1
STAG2
stromal antigen 2
chr17_-_61988556 0.32 ENST00000309894.5
ENST00000438387.2
ENST00000346606.6
ENST00000561003.1
ENST00000450719.3
ENST00000259003.10
CSHL1
chorionic somatomammotropin hormone-like 1
chr11_+_111749650 0.32 ENST00000528125.1
C11orf1
chromosome 11 open reading frame 1
chr1_+_114472481 0.32 ENST00000369555.2
HIPK1
homeodomain interacting protein kinase 1
chr10_+_135050908 0.31 ENST00000325980.9
VENTX
VENT homeobox
chr11_-_74660159 0.31 ENST00000527087.1
ENST00000321448.8
ENST00000340360.6
XRRA1
X-ray radiation resistance associated 1
chr1_+_114471972 0.31 ENST00000369559.4
ENST00000369554.2
HIPK1
homeodomain interacting protein kinase 1
chr14_-_62217779 0.31 ENST00000554254.1
HIF1A-AS2
HIF1A antisense RNA 2
chr15_+_41913690 0.30 ENST00000563576.1
MGA
MGA, MAX dimerization protein
chr2_+_219081817 0.30 ENST00000315717.5
ENST00000420104.1
ENST00000295685.10
ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr16_+_2587965 0.30 ENST00000342085.4
ENST00000566659.1
PDPK1
3-phosphoinositide dependent protein kinase-1
chr5_-_78809950 0.30 ENST00000334082.6
HOMER1
homer homolog 1 (Drosophila)
chr5_+_74807581 0.29 ENST00000241436.4
ENST00000352007.5
POLK
polymerase (DNA directed) kappa
chr8_-_123793048 0.29 ENST00000607710.1
RP11-44N11.2
RP11-44N11.2
chr16_+_2588012 0.29 ENST00000354836.5
ENST00000389224.3
PDPK1
3-phosphoinositide dependent protein kinase-1
chr12_-_18890940 0.29 ENST00000543242.1
ENST00000539072.1
ENST00000541966.1
ENST00000266505.7
ENST00000447925.2
ENST00000435379.1
PLCZ1
phospholipase C, zeta 1
chr2_+_61108650 0.28 ENST00000295025.8
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr14_-_65569244 0.28 ENST00000557277.1
ENST00000556892.1
MAX
MYC associated factor X
chr6_+_30295036 0.28 ENST00000376659.5
ENST00000428555.1
TRIM39
tripartite motif containing 39
chr3_-_66551351 0.27 ENST00000273261.3
LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr11_+_1940786 0.27 ENST00000278317.6
ENST00000381561.4
ENST00000381548.3
ENST00000360603.3
ENST00000381549.3
TNNT3
troponin T type 3 (skeletal, fast)
chr3_-_197024394 0.26 ENST00000434148.1
ENST00000412364.2
ENST00000436682.1
ENST00000456699.2
ENST00000392380.2
DLG1
discs, large homolog 1 (Drosophila)
chr11_+_4116054 0.25 ENST00000423050.2
RRM1
ribonucleotide reductase M1
chr11_-_7818520 0.25 ENST00000329434.2
OR5P2
olfactory receptor, family 5, subfamily P, member 2
chr17_+_57970469 0.25 ENST00000443572.2
ENST00000406116.3
ENST00000225577.4
ENST00000393021.3
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
chr2_+_176972000 0.25 ENST00000249504.5
HOXD11
homeobox D11
chr6_-_31619697 0.24 ENST00000434444.1
BAG6
BCL2-associated athanogene 6
chr6_-_31619892 0.24 ENST00000454165.1
ENST00000428326.1
ENST00000452994.1
BAG6
BCL2-associated athanogene 6
chr17_-_61996136 0.24 ENST00000342364.4
GH1
growth hormone 1
chr11_+_93754513 0.23 ENST00000315765.9
HEPHL1
hephaestin-like 1
chr1_-_182641367 0.23 ENST00000508450.1
RGS8
regulator of G-protein signaling 8
chr17_-_39203519 0.23 ENST00000542137.1
ENST00000391419.3
KRTAP2-1
keratin associated protein 2-1
chr11_+_17568920 0.23 ENST00000399391.2
OTOG
otogelin
chr6_+_79577189 0.23 ENST00000369940.2
IRAK1BP1
interleukin-1 receptor-associated kinase 1 binding protein 1
chr1_+_151584544 0.22 ENST00000458013.2
ENST00000368843.3
SNX27
sorting nexin family member 27
chr6_+_30294612 0.22 ENST00000440271.1
ENST00000396551.3
ENST00000376656.4
ENST00000540416.1
ENST00000428728.1
ENST00000396548.1
ENST00000428404.1
TRIM39
tripartite motif containing 39
chr4_-_114682936 0.22 ENST00000454265.2
ENST00000429180.1
ENST00000418639.2
ENST00000394526.2
ENST00000296402.5
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr1_+_145507587 0.22 ENST00000330165.8
ENST00000369307.3
RBM8A
RNA binding motif protein 8A
chrM_+_10053 0.22 ENST00000361227.2
MT-ND3
mitochondrially encoded NADH dehydrogenase 3
chr13_-_52027134 0.22 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6
integrator complex subunit 6
chr1_+_114472222 0.22 ENST00000369558.1
ENST00000369561.4
HIPK1
homeodomain interacting protein kinase 1
chr15_+_76016293 0.21 ENST00000332145.2
ODF3L1
outer dense fiber of sperm tails 3-like 1
chr3_-_52443799 0.21 ENST00000470173.1
ENST00000296288.5
BAP1
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr2_-_37458749 0.21 ENST00000234170.5
CEBPZ
CCAAT/enhancer binding protein (C/EBP), zeta
chr6_+_49467671 0.21 ENST00000371197.4
ENST00000545705.1
GLYATL3
glycine-N-acyltransferase-like 3
chr11_-_62689046 0.20 ENST00000306960.3
ENST00000543973.1
CHRM1
cholinergic receptor, muscarinic 1
chrX_+_69642881 0.20 ENST00000453994.2
ENST00000536730.1
ENST00000538649.1
ENST00000374382.3
GDPD2
glycerophosphodiester phosphodiesterase domain containing 2
chr5_+_74807886 0.20 ENST00000514296.1
POLK
polymerase (DNA directed) kappa
chr4_-_146859623 0.20 ENST00000379448.4
ENST00000513320.1
ZNF827
zinc finger protein 827
chr3_+_167453493 0.19 ENST00000295777.5
ENST00000472747.2
SERPINI1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr4_-_114682597 0.18 ENST00000394524.3
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr16_+_57139933 0.17 ENST00000566259.1
CPNE2
copine II
chr2_-_160472952 0.17 ENST00000541068.2
ENST00000355831.2
ENST00000343439.5
ENST00000392782.1
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr16_+_67596310 0.17 ENST00000264010.4
ENST00000401394.1
CTCF
CCCTC-binding factor (zinc finger protein)
chr6_-_31619742 0.17 ENST00000433828.1
ENST00000456286.1
BAG6
BCL2-associated athanogene 6
chr11_-_114271139 0.16 ENST00000325636.4
C11orf71
chromosome 11 open reading frame 71
chr3_-_66551397 0.16 ENST00000383703.3
LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chrM_+_10464 0.15 ENST00000361335.1
MT-ND4L
mitochondrially encoded NADH dehydrogenase 4L
chr11_-_128737259 0.15 ENST00000440599.2
ENST00000392666.1
ENST00000324036.3
KCNJ1
potassium inwardly-rectifying channel, subfamily J, member 1
chr4_-_114682719 0.14 ENST00000394522.3
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr11_-_74660065 0.14 ENST00000525407.1
ENST00000528219.1
ENST00000531852.1
XRRA1
X-ray radiation resistance associated 1
chr4_-_140222358 0.14 ENST00000505036.1
ENST00000544855.1
ENST00000539002.1
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr4_+_102268904 0.14 ENST00000527564.1
ENST00000529296.1
AP001816.1
Uncharacterized protein
chr14_+_93897272 0.14 ENST00000393151.2
UNC79
unc-79 homolog (C. elegans)
chr2_+_154728426 0.14 ENST00000392825.3
ENST00000434213.1
GALNT13
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 (GalNAc-T13)
chr11_-_65629497 0.13 ENST00000532134.1
CFL1
cofilin 1 (non-muscle)
chr15_+_60296421 0.13 ENST00000396057.4
FOXB1
forkhead box B1
chr6_+_132873832 0.13 ENST00000275200.1
TAAR8
trace amine associated receptor 8
chr11_+_111750206 0.12 ENST00000530214.1
ENST00000530799.1
C11orf1
chromosome 11 open reading frame 1
chr13_-_46543805 0.12 ENST00000378921.2
ZC3H13
zinc finger CCCH-type containing 13
chr14_+_23344345 0.12 ENST00000551466.1
LRP10
low density lipoprotein receptor-related protein 10
chr14_+_21467414 0.12 ENST00000554422.1
ENST00000298681.4
SLC39A2
solute carrier family 39 (zinc transporter), member 2
chr7_-_76255444 0.12 ENST00000454397.1
POMZP3
POM121 and ZP3 fusion
chr14_+_93897199 0.12 ENST00000553484.1
UNC79
unc-79 homolog (C. elegans)
chr4_+_8582287 0.11 ENST00000382487.4
GPR78
G protein-coupled receptor 78
chr9_-_74980113 0.11 ENST00000376962.5
ENST00000376960.4
ENST00000237937.3
ZFAND5
zinc finger, AN1-type domain 5
chr1_+_26737253 0.11 ENST00000326279.6
LIN28A
lin-28 homolog A (C. elegans)
chr2_-_160473114 0.10 ENST00000392783.2
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr14_-_21058982 0.10 ENST00000556526.1
RNASE12
ribonuclease, RNase A family, 12 (non-active)
chr15_+_76030311 0.09 ENST00000543887.1
AC019294.1
AC019294.1
chr14_-_45603657 0.08 ENST00000396062.3
FKBP3
FK506 binding protein 3, 25kDa

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:0002384 hepatic immune response(GO:0002384)
0.4 1.5 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.2 0.7 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.2 2.2 GO:0001661 conditioned taste aversion(GO:0001661)
0.2 0.9 GO:0060032 notochord regression(GO:0060032)
0.2 0.7 GO:0051389 inactivation of MAPKK activity(GO:0051389)
0.2 0.6 GO:0021569 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.2 0.6 GO:0021934 medulla oblongata development(GO:0021550) hindbrain tangential cell migration(GO:0021934) lateral line system development(GO:0048925)
0.2 1.0 GO:0036309 protein localization to M-band(GO:0036309)
0.1 2.3 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 4.5 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.1 1.9 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.1 0.4 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 0.5 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.1 0.5 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.4 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 0.3 GO:0007343 egg activation(GO:0007343)
0.1 0.8 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.1 1.2 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.1 0.6 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
0.1 1.0 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.1 0.3 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.1 0.5 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 1.1 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 0.6 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 0.3 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 0.4 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.1 3.9 GO:0007340 acrosome reaction(GO:0007340)
0.1 1.0 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1 0.6 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1 0.4 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1 0.6 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.1 0.9 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 1.0 GO:1901725 regulation of histone deacetylase activity(GO:1901725)
0.1 0.7 GO:0030091 protein repair(GO:0030091)
0.1 0.6 GO:0006013 mannose metabolic process(GO:0006013)
0.1 0.2 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1 0.5 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.3 GO:0003138 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 1.2 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0 4.4 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.8 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.5 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.3 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.0 1.3 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 1.0 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 1.3 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.5 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.1 GO:0007412 axon target recognition(GO:0007412)
0.0 0.4 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.7 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.2 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.0 0.2 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.7 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.9 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.3 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.0 0.5 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.0 0.1 GO:1904783 positive regulation of NMDA glutamate receptor activity(GO:1904783)
0.0 0.3 GO:1990118 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.0 0.3 GO:0007379 segment specification(GO:0007379)
0.0 0.4 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.2 GO:0001767 establishment of lymphocyte polarity(GO:0001767)
0.0 0.3 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.8 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.6 GO:0003016 respiratory system process(GO:0003016)
0.0 0.5 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.4 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.3 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.3 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.7 GO:0001662 behavioral fear response(GO:0001662) behavioral defense response(GO:0002209)
0.0 0.1 GO:0060574 intestinal epithelial cell maturation(GO:0060574)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.3 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.3 2.3 GO:0035976 AP1 complex(GO:0035976)
0.2 2.5 GO:0005955 calcineurin complex(GO:0005955)
0.2 0.6 GO:0070195 growth hormone receptor complex(GO:0070195)
0.1 0.3 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 0.7 GO:0032584 growth cone membrane(GO:0032584)
0.1 0.8 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.5 GO:0043196 varicosity(GO:0043196)
0.1 0.6 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.4 GO:0031415 NatA complex(GO:0031415)
0.0 0.5 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.3 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 0.8 GO:0001741 XY body(GO:0001741)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 0.4 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.6 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 2.3 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.3 GO:0097025 lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.9 GO:0097546 ciliary base(GO:0097546)
0.0 0.4 GO:0031904 endosome lumen(GO:0031904)
0.0 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 1.0 GO:0031430 M band(GO:0031430)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 1.0 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 2.4 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.4 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)
0.0 0.3 GO:0005861 troponin complex(GO:0005861)
0.0 0.5 GO:0042629 mast cell granule(GO:0042629)
0.0 0.6 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.3 0.9 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.2 0.6 GO:0005148 prolactin receptor binding(GO:0005148)
0.2 2.5 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.7 GO:0097001 ceramide binding(GO:0097001)
0.1 0.6 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.1 1.0 GO:0030882 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.1 0.7 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 4.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.8 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 1.0 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.5 GO:0051373 FATZ binding(GO:0051373)
0.1 2.0 GO:0031432 titin binding(GO:0031432)
0.1 2.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 3.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 1.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.5 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 0.7 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.3 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.1 0.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.5 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.4 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.4 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 3.6 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 1.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.5 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.5 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.2 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.3 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.2 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.6 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.2 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 1.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.7 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.4 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.3 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.1 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 1.2 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.5 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.3 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 1.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.0 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 ST STAT3 PATHWAY STAT3 Pathway
0.1 5.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 2.7 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 1.0 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.8 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.7 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 3.6 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.1 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.9 PID INSULIN PATHWAY Insulin Pathway
0.0 0.9 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 2.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 1.4 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 1.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 2.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.9 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 1.0 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 1.0 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.7 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.5 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.3 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.5 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling