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Illumina Body Map 2: averaged replicates

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Results for TCF21

Z-value: 1.92

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Transcription factors associated with TCF21

Gene Symbol Gene ID Gene Info
ENSG00000118526.6 transcription factor 21

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TCF21hg19_v2_chr6_+_134210243_1342102760.029.2e-01Click!

Activity profile of TCF21 motif

Sorted Z-values of TCF21 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_45826125 5.92 ENST00000221476.3
creatine kinase, muscle
chr11_+_1944054 4.65 ENST00000397301.1
ENST00000397304.2
ENST00000446240.1
troponin T type 3 (skeletal, fast)
chr17_+_45286387 3.72 ENST00000572316.1
ENST00000354968.1
ENST00000576874.1
ENST00000536623.2
myosin, light chain 4, alkali; atrial, embryonic
chr1_+_171154347 3.47 ENST00000209929.7
ENST00000441535.1
flavin containing monooxygenase 2 (non-functional)
chr16_-_31439735 3.16 ENST00000287490.4
cytochrome c oxidase subunit VIa polypeptide 2
chr3_+_8775466 2.94 ENST00000343849.2
ENST00000397368.2
caveolin 3
chr17_+_4487294 2.81 ENST00000338859.4
smoothelin-like 2
chr3_+_148583043 2.73 ENST00000296046.3
carboxypeptidase A3 (mast cell)
chr8_+_86351056 2.63 ENST00000285381.2
carbonic anhydrase III, muscle specific
chr2_-_152590946 2.63 ENST00000172853.10
nebulin
chr1_+_78354330 2.61 ENST00000440324.1
nexilin (F actin binding protein)
chr1_+_167063282 2.57 ENST00000361200.2
dual specificity phosphatase 27 (putative)
chr1_+_78354297 2.57 ENST00000334785.7
nexilin (F actin binding protein)
chr1_+_78354175 2.54 ENST00000401035.3
ENST00000457030.1
ENST00000330010.8
nexilin (F actin binding protein)
chr17_+_45286706 2.46 ENST00000393450.1
ENST00000572303.1
myosin, light chain 4, alkali; atrial, embryonic
chr15_+_57891609 2.39 ENST00000569089.1
myocardial zonula adherens protein
chr16_+_55522536 2.31 ENST00000570283.1
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr1_+_78354243 2.24 ENST00000294624.8
nexilin (F actin binding protein)
chr6_-_139613269 2.16 ENST00000358430.3
taxilin beta
chr19_+_11651942 2.15 ENST00000587087.1
calponin 1, basic, smooth muscle
chrX_+_128872998 2.08 ENST00000371106.3
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
chr10_-_97200772 2.01 ENST00000371241.1
ENST00000354106.3
ENST00000371239.1
ENST00000361941.3
ENST00000277982.5
ENST00000371245.3
sorbin and SH3 domain containing 1
chr19_+_48216600 2.01 ENST00000263277.3
ENST00000538399.1
EH-domain containing 2
chrX_+_128872918 2.00 ENST00000371105.3
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
chr10_-_29923893 2.00 ENST00000355867.4
supervillin
chr14_-_106830057 1.97 ENST00000390616.2
immunoglobulin heavy variable 4-34
chr19_-_4535233 1.95 ENST00000381848.3
ENST00000588887.1
ENST00000586133.1
perilipin 5
chr9_-_89562104 1.95 ENST00000298743.7
growth arrest-specific 1
chr1_+_171217677 1.93 ENST00000402921.2
flavin containing monooxygenase 1
chr7_-_44105158 1.84 ENST00000297283.3
phosphoglycerate mutase 2 (muscle)
chr20_-_3687775 1.79 ENST00000344754.4
ENST00000202578.4
sialic acid binding Ig-like lectin 1, sialoadhesin
chr16_+_83932684 1.79 ENST00000262430.4
malonyl-CoA decarboxylase
chr17_+_41003166 1.78 ENST00000308423.2
amine oxidase, copper containing 3
chr10_-_7661623 1.77 ENST00000298441.6
inter-alpha-trypsin inhibitor heavy chain family, member 5
chr2_-_42160486 1.73 ENST00000427054.1
AC104654.2
chr8_-_41522719 1.67 ENST00000335651.6
ankyrin 1, erythrocytic
chr4_+_169633310 1.66 ENST00000510998.1
palladin, cytoskeletal associated protein
chr20_-_3662866 1.65 ENST00000356518.2
ENST00000379861.4
ADAM metallopeptidase domain 33
chr6_+_53948221 1.61 ENST00000460844.2
muscular LMNA-interacting protein
chr6_+_53948328 1.61 ENST00000370876.2
muscular LMNA-interacting protein
chr6_+_116832789 1.61 ENST00000368599.3
family with sequence similarity 26, member E
chr12_-_10875831 1.60 ENST00000279550.7
ENST00000228251.4
Y box binding protein 3
chr15_+_63340775 1.50 ENST00000559281.1
ENST00000317516.7
tropomyosin 1 (alpha)
chr7_+_120716625 1.50 ENST00000443817.1
cadherin-like and PC-esterase domain containing 1
chr3_-_81792780 1.50 ENST00000489715.1
glucan (1,4-alpha-), branching enzyme 1
chr9_+_133285948 1.49 ENST00000428715.1
hemicentin 2
chr1_+_186265399 1.46 ENST00000367486.3
ENST00000367484.3
ENST00000533951.1
ENST00000367482.4
ENST00000367483.4
ENST00000367485.4
ENST00000445192.2
proteoglycan 4
chr3_-_105587879 1.41 ENST00000264122.4
ENST00000403724.1
ENST00000405772.1
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr15_+_63340858 1.39 ENST00000560615.1
tropomyosin 1 (alpha)
chr17_+_77030267 1.38 ENST00000581774.1
C1q and tumor necrosis factor related protein 1
chr2_+_137523086 1.36 ENST00000409968.1
thrombospondin, type I, domain containing 7B
chr2_-_3595547 1.34 ENST00000438485.1
Uncharacterized protein
chr1_+_172422026 1.33 ENST00000367725.4
chromosome 1 open reading frame 105
chr1_+_153600869 1.32 ENST00000292169.1
ENST00000368696.3
ENST00000436839.1
S100 calcium binding protein A1
chr22_+_44427230 1.32 ENST00000444029.1
parvin, beta
chr11_+_47270475 1.31 ENST00000481889.2
ENST00000436778.1
ENST00000531660.1
ENST00000407404.1
nuclear receptor subfamily 1, group H, member 3
chr1_+_171217622 1.30 ENST00000433267.1
ENST00000367750.3
flavin containing monooxygenase 1
chr11_+_47270436 1.29 ENST00000395397.3
ENST00000405576.1
nuclear receptor subfamily 1, group H, member 3
chr17_-_53809473 1.27 ENST00000575734.1
transmembrane protein 100
chr22_+_38071615 1.27 ENST00000215909.5
lectin, galactoside-binding, soluble, 1
chr11_+_827553 1.25 ENST00000528542.2
ENST00000450448.1
EF-hand calcium binding domain 4A
chr2_-_128400788 1.24 ENST00000409286.1
LIM and senescent cell antigen-like domains 2
chr17_-_46657473 1.24 ENST00000332503.5
homeobox B4
chr11_-_75921780 1.23 ENST00000529461.1
wingless-type MMTV integration site family, member 11
chr3_-_168864315 1.22 ENST00000475754.1
ENST00000484519.1
MDS1 and EVI1 complex locus
chr19_+_50191921 1.18 ENST00000420022.3
adrenomedullin 5 (putative)
chr15_-_79103757 1.16 ENST00000388820.4
ADAM metallopeptidase with thrombospondin type 1 motif, 7
chr3_-_52868931 1.16 ENST00000486659.1
musculoskeletal, embryonic nuclear protein 1
chrX_-_33357558 1.15 ENST00000288447.4
dystrophin
chr9_+_112852477 1.14 ENST00000480388.1
A kinase (PRKA) anchor protein 2
chr1_+_22963158 1.13 ENST00000438241.1
complement component 1, q subcomponent, A chain
chr2_+_220299547 1.11 ENST00000312358.7
SPEG complex locus
chr1_-_161993422 1.10 ENST00000367940.2
olfactomedin-like 2B
chr12_-_66035968 1.10 ENST00000537250.1
RP11-230G5.2
chr15_+_63340734 1.09 ENST00000560959.1
tropomyosin 1 (alpha)
chr3_+_157261035 1.08 ENST00000312275.5
chromosome 3 open reading frame 55
chr3_+_145782358 1.07 ENST00000422482.1
HCG1786590; PRO2533; Uncharacterized protein
chr20_-_52210368 1.07 ENST00000371471.2
zinc finger protein 217
chr8_+_144295067 1.07 ENST00000330824.2
glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
chr7_-_47578840 1.06 ENST00000450444.1
tensin 3
chr18_+_3448455 1.05 ENST00000549780.1
TGFB-induced factor homeobox 1
chr8_-_41522779 1.04 ENST00000522231.1
ENST00000314214.8
ENST00000348036.4
ENST00000457297.1
ENST00000522543.1
ankyrin 1, erythrocytic
chr3_+_14862939 1.03 ENST00000457774.1
FYVE, RhoGEF and PH domain containing 5
chr6_-_39197226 1.03 ENST00000359534.3
potassium channel, subfamily K, member 5
chr9_+_27109133 1.03 ENST00000519097.1
ENST00000380036.4
TEK tyrosine kinase, endothelial
chr2_-_106054952 1.02 ENST00000336660.5
ENST00000393352.3
ENST00000607522.1
four and a half LIM domains 2
chr9_+_27109392 1.02 ENST00000406359.4
TEK tyrosine kinase, endothelial
chr6_-_72130472 1.02 ENST00000426635.2
long intergenic non-protein coding RNA 472
chr19_+_46801639 1.01 ENST00000244303.6
ENST00000339613.2
ENST00000533145.1
ENST00000472815.1
hypoxia inducible factor 3, alpha subunit
chr6_+_44184653 1.00 ENST00000573382.2
ENST00000576476.1
RP1-302G2.5
chr5_+_135364584 1.00 ENST00000442011.2
ENST00000305126.8
transforming growth factor, beta-induced, 68kDa
chr15_+_63354769 0.99 ENST00000558910.1
tropomyosin 1 (alpha)
chr12_-_92821922 0.98 ENST00000538965.1
ENST00000378487.2
chronic lymphocytic leukemia up-regulated 1 opposite strand
chr9_-_104357277 0.97 ENST00000374806.1
protein phosphatase 3, regulatory subunit B, beta
chr2_+_56411131 0.97 ENST00000407595.2
coiled-coil domain containing 85A
chr11_-_16419067 0.97 ENST00000533411.1
SRY (sex determining region Y)-box 6
chr18_+_3247779 0.96 ENST00000578611.1
ENST00000583449.1
myosin, light chain 12A, regulatory, non-sarcomeric
chr3_-_52869205 0.96 ENST00000446157.2
musculoskeletal, embryonic nuclear protein 1
chr16_+_30383613 0.96 ENST00000568749.1
myosin light chain, phosphorylatable, fast skeletal muscle
chr11_-_59633951 0.94 ENST00000257264.3
transcobalamin I (vitamin B12 binding protein, R binder family)
chr13_-_78492955 0.93 ENST00000446573.1
endothelin receptor type B
chr2_+_102721023 0.92 ENST00000409589.1
ENST00000409329.1
interleukin 1 receptor, type I
chr18_+_21529811 0.92 ENST00000588004.1
laminin, alpha 3
chr7_-_47988088 0.91 ENST00000289672.2
polycystic kidney disease 1 like 1
chr22_+_39052632 0.91 ENST00000411557.1
ENST00000396811.2
ENST00000216029.3
ENST00000416285.1
chibby homolog 1 (Drosophila)
chr12_-_50677255 0.91 ENST00000551691.1
ENST00000394943.3
ENST00000341247.4
LIM domain and actin binding 1
chr11_-_10920714 0.91 ENST00000533941.1
CTD-2003C8.2
chr6_-_3912207 0.90 ENST00000566733.1
RP1-140K8.5
chr2_+_177001685 0.90 ENST00000432796.2
homeobox D3
chr11_+_72975524 0.90 ENST00000540342.1
ENST00000542092.1
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr8_-_123706338 0.90 ENST00000521608.1
long intergenic non-protein coding RNA 1151
chr7_-_42276612 0.89 ENST00000395925.3
ENST00000437480.1
GLI family zinc finger 3
chr19_-_40324767 0.89 ENST00000601972.1
ENST00000430012.2
ENST00000323039.5
ENST00000348817.3
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr1_+_22962948 0.88 ENST00000374642.3
complement component 1, q subcomponent, A chain
chr7_+_20687017 0.87 ENST00000258738.6
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr3_+_32433154 0.87 ENST00000334983.5
ENST00000349718.4
CKLF-like MARVEL transmembrane domain containing 7
chr12_-_52912901 0.86 ENST00000551188.1
keratin 5
chr7_-_122342988 0.86 ENST00000434824.1
ring finger protein 148
chr15_-_99548775 0.86 ENST00000378919.6
pyroglutamyl-peptidase I-like
chr1_-_160681593 0.86 ENST00000368045.3
ENST00000368046.3
CD48 molecule
chr3_+_32433363 0.86 ENST00000465248.1
CKLF-like MARVEL transmembrane domain containing 7
chr4_+_106816592 0.84 ENST00000379987.2
ENST00000453617.2
ENST00000427316.2
ENST00000514622.1
ENST00000305572.8
nephronectin
chr4_+_106816644 0.84 ENST00000506666.1
ENST00000503451.1
nephronectin
chr22_+_23264766 0.84 ENST00000390331.2
immunoglobulin lambda constant 7
chr7_-_132766818 0.84 ENST00000262570.5
coiled-coil-helix-coiled-coil-helix domain containing 3
chr8_-_55014415 0.84 ENST00000522007.1
ENST00000521898.1
ENST00000518546.1
ENST00000316963.3
lysophospholipase I
chr12_+_8850471 0.83 ENST00000535829.1
ENST00000357529.3
ribosomal modification protein rimK-like family member B
chr12_-_104443890 0.83 ENST00000547583.1
ENST00000360814.4
ENST00000546851.1
glycosyltransferase 8 domain containing 2
chr7_-_128415844 0.82 ENST00000249389.2
opsin 1 (cone pigments), short-wave-sensitive
chr19_-_1650666 0.81 ENST00000588136.1
transcription factor 3
chr3_-_105588231 0.81 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr11_-_31531121 0.81 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr17_-_7297833 0.81 ENST00000571802.1
ENST00000576201.1
ENST00000573213.1
ENST00000324822.11
TMEM256-PLSCR3 readthrough (NMD candidate)
chr11_+_1892102 0.80 ENST00000417766.1
lymphocyte-specific protein 1
chr9_+_27109440 0.80 ENST00000519080.1
TEK tyrosine kinase, endothelial
chr15_+_63340647 0.79 ENST00000404484.4
tropomyosin 1 (alpha)
chrX_-_106960285 0.79 ENST00000503515.1
ENST00000372397.2
TSC22 domain family, member 3
chr19_-_7764960 0.78 ENST00000593418.1
Fc fragment of IgE, low affinity II, receptor for (CD23)
chr17_-_79805146 0.77 ENST00000415593.1
prolyl 4-hydroxylase, beta polypeptide
chr3_-_189839467 0.77 ENST00000426003.1
leprecan-like 1
chrX_+_150884539 0.77 ENST00000417321.1
fetal and adult testis expressed 1
chr14_-_93214915 0.76 ENST00000553918.1
ENST00000555699.1
ENST00000553802.1
ENST00000554397.1
ENST00000554919.1
ENST00000554080.1
ENST00000553371.1
legumain
chr3_-_176915215 0.75 ENST00000457928.2
ENST00000422442.1
transducin (beta)-like 1 X-linked receptor 1
chr17_-_7193711 0.74 ENST00000571464.1
Y box binding protein 2
chr20_-_23030296 0.74 ENST00000377103.2
thrombomodulin
chr7_-_132766800 0.74 ENST00000542753.1
ENST00000448878.1
coiled-coil-helix-coiled-coil-helix domain containing 3
chr6_-_30658745 0.72 ENST00000376420.5
ENST00000376421.5
nurim (nuclear envelope membrane protein)
chr7_+_150413645 0.72 ENST00000307194.5
GTPase, IMAP family member 1
chr17_+_71229346 0.71 ENST00000535032.2
ENST00000582793.1
chromosome 17 open reading frame 80
chr11_+_64002292 0.71 ENST00000426086.2
vascular endothelial growth factor B
chr1_-_45476944 0.71 ENST00000372172.4
HECT domain containing E3 ubiquitin protein ligase 3
chr2_+_219264466 0.70 ENST00000273062.2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr2_-_25100893 0.70 ENST00000433852.1
adenylate cyclase 3
chr6_-_41673552 0.70 ENST00000419574.1
ENST00000445214.1
transcription factor EB
chr2_+_159825143 0.70 ENST00000454300.1
ENST00000263635.6
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chr17_+_39261584 0.70 ENST00000391415.1
keratin associated protein 4-9
chr3_-_112013071 0.70 ENST00000487372.1
ENST00000486574.1
ENST00000305815.5
solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1
chr12_+_16500571 0.70 ENST00000543076.1
ENST00000396210.3
microsomal glutathione S-transferase 1
chr11_-_74660065 0.69 ENST00000525407.1
ENST00000528219.1
ENST00000531852.1
X-ray radiation resistance associated 1
chr1_+_212738676 0.69 ENST00000366981.4
ENST00000366987.2
activating transcription factor 3
chr11_+_72975578 0.68 ENST00000393592.2
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr22_+_40742512 0.68 ENST00000454266.2
ENST00000342312.6
adenylosuccinate lyase
chr11_-_82746587 0.68 ENST00000528379.1
ENST00000534103.1
RAB30, member RAS oncogene family
chr15_-_42749711 0.67 ENST00000565611.1
ENST00000263805.4
ENST00000565948.1
zinc finger protein 106
chr19_-_49828438 0.67 ENST00000454748.3
ENST00000598828.1
ENST00000335875.4
solute carrier family 6, member 16
chr2_-_90538397 0.66 ENST00000443397.3
Uncharacterized protein
chr11_+_72975559 0.66 ENST00000349767.2
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr2_+_192110199 0.66 ENST00000304164.4
myosin IB
chr4_+_123844225 0.66 ENST00000274008.4
spermatogenesis associated 5
chr13_-_78492927 0.66 ENST00000334286.5
endothelin receptor type B
chr22_+_31460091 0.65 ENST00000432777.1
ENST00000422839.1
smoothelin
chr17_-_46671323 0.65 ENST00000239151.5
homeobox B5
chrX_-_11445856 0.65 ENST00000380736.1
Rho GTPase activating protein 6
chr11_-_62457371 0.64 ENST00000317449.4
LRRN4 C-terminal like
chr6_-_31697255 0.64 ENST00000436437.1
dimethylarginine dimethylaminohydrolase 2
chr12_-_52845910 0.63 ENST00000252252.3
keratin 6B
chr4_+_114214125 0.63 ENST00000509550.1
ankyrin 2, neuronal
chr21_-_31933633 0.63 ENST00000334849.2
keratin associated protein 19-7
chr2_+_90273679 0.62 ENST00000423080.2
immunoglobulin kappa variable 3D-7
chr18_-_6929797 0.61 ENST00000581725.1
ENST00000583316.1
long intergenic non-protein coding RNA 668
chr19_+_50016610 0.61 ENST00000596975.1
Fc fragment of IgG, receptor, transporter, alpha
chr21_+_17791648 0.61 ENST00000602892.1
ENST00000418813.2
ENST00000435697.1
long intergenic non-protein coding RNA 478
chr15_+_63340553 0.61 ENST00000334895.5
tropomyosin 1 (alpha)
chr11_+_117103333 0.60 ENST00000534428.1
ring finger protein 214
chr22_+_44351301 0.60 ENST00000350028.4
SAMM50 sorting and assembly machinery component
chr11_-_64512469 0.59 ENST00000377485.1
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr11_+_1874200 0.59 ENST00000311604.3
lymphocyte-specific protein 1
chr12_+_16500599 0.58 ENST00000535309.1
ENST00000540056.1
ENST00000396209.1
ENST00000540126.1
microsomal glutathione S-transferase 1
chr1_+_92414952 0.58 ENST00000449584.1
ENST00000427104.1
ENST00000355011.3
ENST00000448194.1
ENST00000426141.1
ENST00000450792.1
ENST00000548992.1
ENST00000552654.1
ENST00000457265.1
bromodomain, testis-specific
chr5_-_98262240 0.58 ENST00000284049.3
chromodomain helicase DNA binding protein 1
chr6_-_31697563 0.57 ENST00000375789.2
ENST00000416410.1
dimethylarginine dimethylaminohydrolase 2
chr7_-_128045984 0.56 ENST00000470772.1
ENST00000480861.1
ENST00000496200.1
IMP (inosine 5'-monophosphate) dehydrogenase 1
chr6_+_30585486 0.56 ENST00000259873.4
ENST00000506373.2
mitochondrial ribosomal protein S18B
chr12_+_113659234 0.56 ENST00000551096.1
ENST00000551099.1
ENST00000335509.6
ENST00000552897.1
ENST00000550785.1
ENST00000549279.1
two pore segment channel 1
chr8_+_134029937 0.56 ENST00000518108.1
thyroglobulin
chr21_+_17791838 0.56 ENST00000453910.1
long intergenic non-protein coding RNA 478
chr9_-_33447584 0.55 ENST00000297991.4
aquaporin 3 (Gill blood group)
chr4_-_8430152 0.55 ENST00000514423.1
ENST00000503233.1
acyl-CoA oxidase 3, pristanoyl
chr11_-_74660159 0.54 ENST00000527087.1
ENST00000321448.8
ENST00000340360.6
X-ray radiation resistance associated 1
chr2_-_228028829 0.53 ENST00000396625.3
ENST00000329662.7
collagen, type IV, alpha 4

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF21

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 6.4 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.7 6.7 GO:0070995 NADPH oxidation(GO:0070995)
0.7 2.0 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.6 1.8 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.6 1.7 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.5 1.6 GO:0007497 posterior midgut development(GO:0007497) endothelin receptor signaling pathway(GO:0086100)
0.5 2.6 GO:0007525 somatic muscle development(GO:0007525)
0.5 2.6 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.5 1.8 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.4 3.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.4 1.3 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.4 1.7 GO:0097195 pilomotor reflex(GO:0097195)
0.4 10.0 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.4 0.4 GO:0043449 cellular alkene metabolic process(GO:0043449)
0.4 1.8 GO:0036115 fatty-acyl-CoA catabolic process(GO:0036115)
0.4 2.8 GO:0048014 Tie signaling pathway(GO:0048014)
0.3 5.9 GO:0006600 creatine metabolic process(GO:0006600)
0.3 1.2 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.3 0.9 GO:0021776 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.3 1.6 GO:0002317 plasma cell differentiation(GO:0002317)
0.3 0.8 GO:0006624 vacuolar protein processing(GO:0006624)
0.3 2.0 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.2 1.2 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.2 2.3 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.2 0.7 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.2 0.9 GO:0009726 detection of endogenous stimulus(GO:0009726)
0.2 0.6 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.2 0.6 GO:0051039 histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.2 0.7 GO:0009386 translational attenuation(GO:0009386)
0.2 0.9 GO:0048749 compound eye development(GO:0048749)
0.2 0.7 GO:0008355 olfactory learning(GO:0008355)
0.2 1.4 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.2 12.5 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.2 0.5 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.2 1.0 GO:0021779 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.2 1.0 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.2 0.9 GO:0098907 regulation of SA node cell action potential(GO:0098907)
0.2 1.2 GO:0048539 bone marrow development(GO:0048539)
0.2 0.9 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.2 1.1 GO:0071503 positive regulation of lipoprotein particle clearance(GO:0010986) response to heparin(GO:0071503)
0.1 1.6 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.1 0.4 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 3.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.7 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.1 1.3 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.1 0.8 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.1 2.1 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.1 0.4 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
0.1 0.4 GO:1901656 glycoside transport(GO:1901656)
0.1 0.7 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.1 2.7 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 0.4 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.1 1.0 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.1 1.9 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.1 0.5 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.1 0.3 GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.1 0.4 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.1 0.8 GO:0002326 B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152)
0.1 1.3 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.1 1.1 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.1 2.2 GO:0002003 angiotensin maturation(GO:0002003)
0.1 1.4 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.1 2.2 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 0.5 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 1.5 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 0.7 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.1 0.6 GO:0090649 renal water absorption(GO:0070295) response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.1 0.8 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.1 0.8 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.5 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.1 0.3 GO:0060152 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.1 0.8 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.1 1.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 0.9 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.1 0.6 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.6 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.1 0.9 GO:0015889 cobalt ion transport(GO:0006824) cobalamin transport(GO:0015889)
0.1 0.4 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
0.1 0.5 GO:0051697 protein delipidation(GO:0051697)
0.1 0.9 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 0.4 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.3 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.1 0.3 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.1 0.8 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.1 0.8 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.1 0.1 GO:0036112 medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.1 0.3 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.1 1.2 GO:0006527 arginine catabolic process(GO:0006527)
0.1 0.2 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.1 2.0 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 1.5 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.2 GO:0045047 protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.1 2.0 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.1 0.3 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 0.8 GO:0060613 fat pad development(GO:0060613)
0.0 1.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.4 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.4 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.7 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.8 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.5 GO:0046886 positive regulation of hormone biosynthetic process(GO:0046886)
0.0 0.2 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.0 0.1 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773) negative regulation of B cell differentiation(GO:0045578) positive regulation of ovulation(GO:0060279)
0.0 0.3 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.1 GO:0035038 female pronucleus assembly(GO:0035038)
0.0 0.4 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.4 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 1.2 GO:2001046 positive regulation of integrin-mediated signaling pathway(GO:2001046)
0.0 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.8 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.5 GO:0042090 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.6 GO:0015705 iodide transport(GO:0015705)
0.0 0.2 GO:0072312 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.0 0.2 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.5 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.5 GO:0042737 drug catabolic process(GO:0042737)
0.0 1.1 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.1 GO:1990637 response to prolactin(GO:1990637)
0.0 0.3 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.7 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 2.0 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.4 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.4 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 2.3 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.5 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 1.2 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.3 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.0 0.1 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.0 0.1 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.4 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.4 GO:0032328 alanine transport(GO:0032328) D-amino acid transport(GO:0042940)
0.0 0.7 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.2 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086) chromatin maintenance(GO:0070827)
0.0 0.8 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.2 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.0 0.7 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 1.8 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.8 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 4.0 GO:0030449 regulation of complement activation(GO:0030449)
0.0 2.4 GO:0000271 polysaccharide biosynthetic process(GO:0000271)
0.0 0.2 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.4 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.5 GO:0051775 response to redox state(GO:0051775)
0.0 1.7 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 2.7 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.7 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 0.1 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.0 0.5 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 1.2 GO:0010165 response to X-ray(GO:0010165)
0.0 1.2 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.3 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.6 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.2 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.1 GO:1904720 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 0.3 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.2 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.3 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0 0.3 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 0.3 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.4 GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069)
0.0 0.1 GO:0042369 vitamin D catabolic process(GO:0042369)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.5 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.0 0.0 GO:0070781 response to biotin(GO:0070781)
0.0 0.6 GO:0007398 ectoderm development(GO:0007398)
0.0 0.8 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.5 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.5 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.1 GO:0060022 hard palate development(GO:0060022)
0.0 1.0 GO:0007588 excretion(GO:0007588)
0.0 0.2 GO:0002097 tRNA wobble base modification(GO:0002097)
0.0 0.9 GO:0031529 ruffle organization(GO:0031529)
0.0 0.5 GO:0001934 positive regulation of protein phosphorylation(GO:0001934)
0.0 0.4 GO:0032060 bleb assembly(GO:0032060)
0.0 0.2 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.1 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.4 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.3 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.5 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.2 GO:0070828 heterochromatin organization(GO:0070828)
0.0 1.6 GO:0006939 smooth muscle contraction(GO:0006939)
0.0 1.0 GO:0006968 cellular defense response(GO:0006968)
0.0 2.4 GO:0031424 keratinization(GO:0031424)
0.0 0.3 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 0.6 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.3 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.3 GO:0032354 response to follicle-stimulating hormone(GO:0032354)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.0 GO:0005602 complement component C1 complex(GO:0005602)
0.3 6.9 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.3 2.0 GO:0005899 insulin receptor complex(GO:0005899)
0.3 1.7 GO:0034678 smooth muscle contractile fiber(GO:0030485) integrin alpha8-beta1 complex(GO:0034678)
0.3 0.8 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.2 0.7 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.2 3.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 1.6 GO:0061617 MICOS complex(GO:0061617)
0.2 4.6 GO:0005861 troponin complex(GO:0005861)
0.2 0.8 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.2 0.7 GO:0045277 respiratory chain complex IV(GO:0045277)
0.1 0.5 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 2.0 GO:0036449 microtubule minus-end(GO:0036449)
0.1 12.3 GO:0031672 A band(GO:0031672)
0.1 0.8 GO:0036021 endolysosome lumen(GO:0036021)
0.1 0.4 GO:0042585 germinal vesicle(GO:0042585)
0.1 1.1 GO:0016013 syntrophin complex(GO:0016013)
0.1 1.5 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.1 0.8 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 19.5 GO:0030018 Z disc(GO:0030018)
0.1 0.9 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.4 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 1.3 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 0.5 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.1 0.5 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 0.3 GO:1990037 Lewy body core(GO:1990037)
0.1 0.7 GO:0030870 Mre11 complex(GO:0030870)
0.1 1.0 GO:0005859 muscle myosin complex(GO:0005859)
0.1 2.7 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.3 GO:0035339 SPOTS complex(GO:0035339)
0.1 3.0 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.4 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.4 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.1 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0 0.3 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.2 GO:1905202 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.0 2.3 GO:0030017 sarcomere(GO:0030017)
0.0 0.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.3 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.3 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.4 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 3.2 GO:0045095 keratin filament(GO:0045095)
0.0 2.6 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.9 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.9 GO:0043218 compact myelin(GO:0043218)
0.0 0.4 GO:0070652 HAUS complex(GO:0070652)
0.0 0.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.7 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.8 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 2.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 2.4 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.5 GO:0071141 SMAD protein complex(GO:0071141)
0.0 1.2 GO:0016459 myosin complex(GO:0016459)
0.0 1.3 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.5 GO:0005844 polysome(GO:0005844)
0.0 2.8 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 2.7 GO:0016605 PML body(GO:0016605)
0.0 0.9 GO:0016592 mediator complex(GO:0016592)
0.0 0.6 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 3.8 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.4 GO:0031105 septin complex(GO:0031105)
0.0 0.5 GO:0044447 axoneme part(GO:0044447)
0.0 0.9 GO:0016235 aggresome(GO:0016235)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.2 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 1.4 GO:0005902 microvillus(GO:0005902)
0.0 1.3 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:0070938 contractile ring(GO:0070938)
0.0 0.8 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.9 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 2.0 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.3 GO:0032420 stereocilium(GO:0032420)
0.0 0.9 GO:0060170 ciliary membrane(GO:0060170)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 6.2 GO:0032038 myosin II heavy chain binding(GO:0032038)
1.2 4.6 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.8 7.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.6 5.9 GO:0004111 creatine kinase activity(GO:0004111)
0.5 1.6 GO:0004962 endothelin receptor activity(GO:0004962)
0.5 1.8 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.4 1.8 GO:0052594 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.4 1.3 GO:0030395 lactose binding(GO:0030395)
0.4 3.0 GO:0035473 lipase binding(GO:0035473)
0.3 2.6 GO:0032810 sterol response element binding(GO:0032810)
0.3 0.8 GO:0072591 citrate-L-glutamate ligase activity(GO:0072591)
0.2 2.9 GO:0071253 connexin binding(GO:0071253)
0.2 2.2 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.2 0.4 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.2 0.7 GO:0047860 diiodophenylpyruvate reductase activity(GO:0047860)
0.2 1.2 GO:0016403 dimethylargininase activity(GO:0016403)
0.2 22.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.2 1.0 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.2 0.5 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.1 0.4 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.1 0.8 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 4.1 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.9 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.1 0.6 GO:0019770 IgG receptor activity(GO:0019770)
0.1 4.2 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.7 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.5 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.1 2.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.6 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.6 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.9 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 0.3 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.1 0.3 GO:0004326 tetrahydrofolylpolyglutamate synthase activity(GO:0004326) dihydrofolate synthase activity(GO:0008841)
0.1 1.7 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 1.7 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.6 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.4 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.1 0.8 GO:0043426 MRF binding(GO:0043426)
0.1 0.8 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 0.7 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 0.2 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.1 3.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.8 GO:0019863 IgE binding(GO:0019863)
0.1 0.5 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.1 0.4 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.1 0.9 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.7 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 1.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 1.3 GO:0043295 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.1 0.8 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.8 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 0.2 GO:0005046 KDEL sequence binding(GO:0005046)
0.1 0.7 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.3 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.1 0.5 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 0.2 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.0 1.5 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 1.3 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.7 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.4 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.4 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.6 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 1.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.2 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.0 0.4 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 1.5 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.4 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 2.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.4 GO:0015250 water channel activity(GO:0015250)
0.0 0.4 GO:0030274 LIM domain binding(GO:0030274)
0.0 2.0 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.4 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.0 5.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.0 0.3 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.1 GO:0008193 RNA guanylyltransferase activity(GO:0008192) tRNA guanylyltransferase activity(GO:0008193)
0.0 2.2 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.3 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.2 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 1.8 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 1.2 GO:0005109 frizzled binding(GO:0005109)
0.0 0.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.7 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.4 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.2 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.7 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.4 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.4 GO:0015197 peptide transporter activity(GO:0015197)
0.0 0.4 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.3 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.2 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.7 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.9 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.4 GO:0070403 NAD+ binding(GO:0070403)
0.0 5.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.5 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.3 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 2.7 GO:0005178 integrin binding(GO:0005178)
0.0 2.0 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.2 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.2 GO:0016289 CoA hydrolase activity(GO:0016289)
0.0 0.0 GO:0016421 CoA carboxylase activity(GO:0016421)
0.0 0.3 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 0.2 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.2 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.9 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.2 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.6 GO:0030507 spectrin binding(GO:0030507)
0.0 0.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.4 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.1 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 1.6 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 1.1 GO:0032947 protein complex scaffold(GO:0032947)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 2.9 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 3.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 5.6 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 3.8 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 3.1 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 2.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 3.1 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.4 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.7 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.5 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 2.8 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.5 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 2.5 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 2.3 PID ENDOTHELIN PATHWAY Endothelins
0.0 3.8 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 2.0 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 1.9 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.5 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.3 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.2 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.9 PID AP1 PATHWAY AP-1 transcription factor network
0.0 1.0 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.3 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 1.2 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.8 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.5 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 16.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 2.0 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 1.7 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 2.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 2.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 1.0 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 2.8 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 7.2 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 0.8 REACTOME OPSINS Genes involved in Opsins
0.1 1.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 0.8 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 1.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 2.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 2.2 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.7 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.7 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.1 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.8 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 1.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 2.6 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.7 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 3.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.1 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.8 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 1.5 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 1.5 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 0.5 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.0 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 1.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.0 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.2 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 1.0 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.5 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 1.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.5 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 3.6 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 1.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.2 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation