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Illumina Body Map 2: averaged replicates

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Results for TFAP4_MSC

Z-value: 2.89

Motif logo

Transcription factors associated with TFAP4_MSC

Gene Symbol Gene ID Gene Info
ENSG00000090447.7 TFAP4
ENSG00000178860.8 MSC

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MSChg19_v2_chr8_-_72756667_72756736-0.522.3e-03Click!
TFAP4hg19_v2_chr16_-_4323015_4323076-0.144.5e-01Click!

Activity profile of TFAP4_MSC motif

Sorted Z-values of TFAP4_MSC motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TFAP4_MSC

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr2_-_152590946 13.64 ENST00000172853.10
NEB
nebulin
chr1_+_167063282 13.43 ENST00000361200.2
DUSP27
dual specificity phosphatase 27 (putative)
chr14_+_32964258 10.84 ENST00000556638.1
AKAP6
A kinase (PRKA) anchor protein 6
chr3_+_8775466 10.13 ENST00000343849.2
ENST00000397368.2
CAV3
caveolin 3
chr2_-_175629135 9.77 ENST00000409542.1
ENST00000409219.1
CHRNA1
cholinergic receptor, nicotinic, alpha 1 (muscle)
chr2_-_175629164 9.69 ENST00000409323.1
ENST00000261007.5
ENST00000348749.5
CHRNA1
cholinergic receptor, nicotinic, alpha 1 (muscle)
chr16_+_30383613 9.59 ENST00000568749.1
MYLPF
myosin light chain, phosphorylatable, fast skeletal muscle
chr4_-_177190364 8.88 ENST00000296525.3
ASB5
ankyrin repeat and SOCS box containing 5
chr17_+_65040678 7.97 ENST00000226021.3
CACNG1
calcium channel, voltage-dependent, gamma subunit 1
chr2_+_27505260 7.50 ENST00000380075.2
ENST00000296098.4
TRIM54
tripartite motif containing 54
chr8_+_86351056 7.09 ENST00000285381.2
CA3
carbonic anhydrase III, muscle specific
chr10_+_88428370 6.53 ENST00000372066.3
ENST00000263066.6
ENST00000372056.4
ENST00000310944.6
ENST00000361373.4
ENST00000542786.1
LDB3
LIM domain binding 3
chr22_-_36013368 6.42 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
MB
myoglobin
chr12_-_57644952 6.24 ENST00000554578.1
ENST00000546246.2
ENST00000553489.1
ENST00000332782.2
STAC3
SH3 and cysteine rich domain 3
chr15_-_42749711 6.10 ENST00000565611.1
ENST00000263805.4
ENST00000565948.1
ZNF106
zinc finger protein 106
chr16_+_7560114 5.68 ENST00000570626.1
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr2_-_179672142 5.66 ENST00000342992.6
ENST00000360870.5
ENST00000460472.2
ENST00000589042.1
ENST00000591111.1
ENST00000342175.6
ENST00000359218.5
TTN
titin
chr1_+_172422026 5.59 ENST00000367725.4
C1orf105
chromosome 1 open reading frame 105
chr8_-_144512576 5.56 ENST00000333480.2
MAFA
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A
chr14_+_32963433 5.53 ENST00000554410.1
AKAP6
A kinase (PRKA) anchor protein 6
chr2_+_233404429 5.50 ENST00000389494.3
ENST00000389492.3
CHRNG
cholinergic receptor, nicotinic, gamma (muscle)
chrX_-_33357558 5.46 ENST00000288447.4
DMD
dystrophin
chr10_-_29923893 5.45 ENST00000355867.4
SVIL
supervillin
chr1_+_46379254 5.12 ENST00000372008.2
MAST2
microtubule associated serine/threonine kinase 2
chr6_+_41021027 5.08 ENST00000244669.2
APOBEC2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
chr20_+_30407105 5.01 ENST00000375994.2
MYLK2
myosin light chain kinase 2
chr20_+_30407151 5.01 ENST00000375985.4
MYLK2
myosin light chain kinase 2
chr17_-_41132088 4.98 ENST00000591916.1
ENST00000451885.2
ENST00000454303.1
PTGES3L
PTGES3L-AARSD1
prostaglandin E synthase 3 (cytosolic)-like
PTGES3L-AARSD1 readthrough
chr22_+_26138108 4.98 ENST00000536101.1
ENST00000335473.7
ENST00000407587.2
MYO18B
myosin XVIIIB
chr1_+_78354243 4.98 ENST00000294624.8
NEXN
nexilin (F actin binding protein)
chr10_+_88428206 4.93 ENST00000429277.2
ENST00000458213.2
ENST00000352360.5
LDB3
LIM domain binding 3
chr3_-_46904946 4.73 ENST00000292327.4
MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr3_-_46904918 4.71 ENST00000395869.1
MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr1_+_78354330 4.69 ENST00000440324.1
NEXN
nexilin (F actin binding protein)
chr5_-_58571935 4.66 ENST00000503258.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr1_-_26394114 4.64 ENST00000374272.3
TRIM63
tripartite motif containing 63, E3 ubiquitin protein ligase
chr2_+_88367299 4.53 ENST00000419482.2
ENST00000444564.2
SMYD1
SET and MYND domain containing 1
chr2_-_227050079 4.41 ENST00000423838.1
AC068138.1
AC068138.1
chr1_+_78354175 4.40 ENST00000401035.3
ENST00000457030.1
ENST00000330010.8
NEXN
nexilin (F actin binding protein)
chr1_+_78354297 4.31 ENST00000334785.7
NEXN
nexilin (F actin binding protein)
chr1_-_216896780 4.20 ENST00000459955.1
ENST00000366937.1
ENST00000408911.3
ENST00000391890.3
ESRRG
estrogen-related receptor gamma
chr8_-_72274095 4.20 ENST00000303824.7
EYA1
eyes absent homolog 1 (Drosophila)
chr1_-_201081579 4.13 ENST00000367338.3
ENST00000362061.3
CACNA1S
calcium channel, voltage-dependent, L type, alpha 1S subunit
chr1_+_203256898 4.08 ENST00000433008.1
RP11-134P9.3
RP11-134P9.3
chr1_+_153600869 3.85 ENST00000292169.1
ENST00000368696.3
ENST00000436839.1
S100A1
S100 calcium binding protein A1
chr2_+_88367368 3.85 ENST00000438570.1
SMYD1
SET and MYND domain containing 1
chr2_-_152590982 3.78 ENST00000409198.1
ENST00000397345.3
ENST00000427231.2
NEB
nebulin
chr20_+_33292507 3.72 ENST00000414082.1
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr11_-_111783595 3.54 ENST00000528628.1
CRYAB
crystallin, alpha B
chr5_+_191592 3.47 ENST00000328278.3
LRRC14B
leucine rich repeat containing 14B
chr17_+_45286387 3.39 ENST00000572316.1
ENST00000354968.1
ENST00000576874.1
ENST00000536623.2
MYL4
myosin, light chain 4, alkali; atrial, embryonic
chr11_+_1944054 3.39 ENST00000397301.1
ENST00000397304.2
ENST00000446240.1
TNNT3
troponin T type 3 (skeletal, fast)
chr16_+_83932684 3.33 ENST00000262430.4
MLYCD
malonyl-CoA decarboxylase
chr17_-_62066769 3.33 ENST00000577329.1
CTC-264K15.6
CTC-264K15.6
chr12_-_70093111 3.33 ENST00000548658.1
ENST00000476098.1
ENST00000331471.4
ENST00000393365.1
BEST3
bestrophin 3
chr6_+_17281573 3.31 ENST00000379052.5
RBM24
RNA binding motif protein 24
chr3_-_52486841 3.29 ENST00000496590.1
TNNC1
troponin C type 1 (slow)
chr12_-_70093190 3.25 ENST00000330891.5
BEST3
bestrophin 3
chr1_-_216896674 3.22 ENST00000475275.1
ENST00000469486.1
ENST00000481543.1
ESRRG
estrogen-related receptor gamma
chr12_-_70093065 3.08 ENST00000553096.1
BEST3
bestrophin 3
chr21_+_30673091 2.93 ENST00000447177.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr10_-_92681033 2.90 ENST00000371697.3
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr21_+_30672433 2.88 ENST00000451655.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr2_+_136343904 2.86 ENST00000436436.1
R3HDM1
R3H domain containing 1
chr8_-_145016692 2.85 ENST00000357649.2
PLEC
plectin
chr2_+_233390863 2.83 ENST00000449596.1
ENST00000543200.1
CHRND
cholinergic receptor, nicotinic, delta (muscle)
chr8_-_75233563 2.79 ENST00000342232.4
JPH1
junctophilin 1
chr1_+_12042015 2.76 ENST00000412236.1
MFN2
mitofusin 2
chr11_+_1860200 2.72 ENST00000381911.1
TNNI2
troponin I type 2 (skeletal, fast)
chr2_-_176867534 2.70 ENST00000445472.1
KIAA1715
KIAA1715
chr3_+_42727011 2.64 ENST00000287777.4
KLHL40
kelch-like family member 40
chr9_+_134165063 2.62 ENST00000372264.3
PPAPDC3
phosphatidic acid phosphatase type 2 domain containing 3
chr6_-_3912207 2.57 ENST00000566733.1
RP1-140K8.5
RP1-140K8.5
chr8_-_72274355 2.57 ENST00000388741.2
EYA1
eyes absent homolog 1 (Drosophila)
chr18_+_7231123 2.56 ENST00000383467.2
LRRC30
leucine rich repeat containing 30
chrX_+_135279179 2.53 ENST00000370676.3
FHL1
four and a half LIM domains 1
chr12_-_54121261 2.52 ENST00000549784.1
ENST00000262059.4
CALCOCO1
calcium binding and coiled-coil domain 1
chr17_+_67410832 2.50 ENST00000590474.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr13_+_41635617 2.49 ENST00000542082.1
WBP4
WW domain binding protein 4
chr12_-_70093162 2.48 ENST00000551160.1
BEST3
bestrophin 3
chr9_+_134165195 2.45 ENST00000372261.1
PPAPDC3
phosphatidic acid phosphatase type 2 domain containing 3
chr2_-_176867501 2.44 ENST00000535310.1
KIAA1715
KIAA1715
chr5_+_150040403 2.40 ENST00000517768.1
ENST00000297130.4
MYOZ3
myozenin 3
chr8_-_72274467 2.39 ENST00000340726.3
EYA1
eyes absent homolog 1 (Drosophila)
chr5_+_102201509 2.37 ENST00000348126.2
ENST00000379787.4
PAM
peptidylglycine alpha-amidating monooxygenase
chr5_+_102201687 2.36 ENST00000304400.7
PAM
peptidylglycine alpha-amidating monooxygenase
chr3_-_81792780 2.34 ENST00000489715.1
GBE1
glucan (1,4-alpha-), branching enzyme 1
chr15_+_86686953 2.30 ENST00000421325.2
AGBL1
ATP/GTP binding protein-like 1
chr10_-_61899124 2.30 ENST00000373815.1
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr12_-_54121212 2.27 ENST00000548263.1
ENST00000430117.2
ENST00000550804.1
ENST00000549173.1
ENST00000551900.1
ENST00000546619.1
ENST00000548177.1
ENST00000549349.1
CALCOCO1
calcium binding and coiled-coil domain 1
chr6_-_125766306 2.27 ENST00000430672.1
RP11-138M12.1
RP11-138M12.1
chr1_-_231560790 2.22 ENST00000366641.3
EGLN1
egl-9 family hypoxia-inducible factor 1
chr2_+_29341037 2.20 ENST00000449202.1
CLIP4
CAP-GLY domain containing linker protein family, member 4
chr8_-_41522779 2.20 ENST00000522231.1
ENST00000314214.8
ENST00000348036.4
ENST00000457297.1
ENST00000522543.1
ANK1
ankyrin 1, erythrocytic
chrX_+_70521584 2.12 ENST00000373829.3
ENST00000538820.1
ITGB1BP2
integrin beta 1 binding protein (melusin) 2
chr5_+_102201722 2.12 ENST00000274392.9
ENST00000455264.2
PAM
peptidylglycine alpha-amidating monooxygenase
chr6_-_110736742 2.12 ENST00000368924.3
ENST00000368923.3
DDO
D-aspartate oxidase
chr22_+_35695793 2.10 ENST00000456128.1
ENST00000449058.2
ENST00000411850.1
ENST00000425375.1
ENST00000436462.2
ENST00000382034.5
TOM1
target of myb1 (chicken)
chr3_-_52868931 2.09 ENST00000486659.1
MUSTN1
musculoskeletal, embryonic nuclear protein 1
chr2_+_136343820 2.08 ENST00000410054.1
R3HDM1
R3H domain containing 1
chr2_+_33701707 2.08 ENST00000425210.1
ENST00000444784.1
ENST00000423159.1
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr1_-_154842741 2.04 ENST00000271915.4
KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr5_+_102201430 2.02 ENST00000438793.3
ENST00000346918.2
PAM
peptidylglycine alpha-amidating monooxygenase
chr19_+_35521616 2.01 ENST00000595652.1
SCN1B
sodium channel, voltage-gated, type I, beta subunit
chr2_-_176866978 2.01 ENST00000392540.2
ENST00000409660.1
ENST00000544803.1
ENST00000272748.4
KIAA1715
KIAA1715
chr19_+_35521572 2.01 ENST00000262631.5
SCN1B
sodium channel, voltage-gated, type I, beta subunit
chrX_+_135278908 1.99 ENST00000539015.1
ENST00000370683.1
FHL1
four and a half LIM domains 1
chr4_-_153303658 1.95 ENST00000296555.5
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr9_-_123239632 1.93 ENST00000416449.1
CDK5RAP2
CDK5 regulatory subunit associated protein 2
chr1_+_10271674 1.93 ENST00000377086.1
KIF1B
kinesin family member 1B
chr20_+_33292068 1.93 ENST00000374810.3
ENST00000374809.2
ENST00000451665.1
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr17_+_45286706 1.91 ENST00000393450.1
ENST00000572303.1
MYL4
myosin, light chain 4, alkali; atrial, embryonic
chrX_-_108868390 1.87 ENST00000372101.2
KCNE1L
KCNE1-like
chr5_-_95158644 1.85 ENST00000237858.6
GLRX
glutaredoxin (thioltransferase)
chr1_-_201346761 1.84 ENST00000455702.1
ENST00000422165.1
ENST00000367318.5
ENST00000367320.2
ENST00000438742.1
ENST00000412633.1
ENST00000458432.2
ENST00000421663.2
ENST00000367322.1
ENST00000509001.1
TNNT2
troponin T type 2 (cardiac)
chr19_-_46285736 1.84 ENST00000291270.4
ENST00000447742.2
ENST00000354227.5
DMPK
dystrophia myotonica-protein kinase
chr1_-_33336414 1.84 ENST00000373471.3
ENST00000609187.1
FNDC5
fibronectin type III domain containing 5
chr3_+_32148106 1.83 ENST00000425459.1
ENST00000431009.1
GPD1L
glycerol-3-phosphate dehydrogenase 1-like
chr7_-_74867509 1.79 ENST00000426327.3
GATSL2
GATS protein-like 2
chr20_-_36152914 1.79 ENST00000397131.1
BLCAP
bladder cancer associated protein
chr3_+_32147997 1.78 ENST00000282541.5
GPD1L
glycerol-3-phosphate dehydrogenase 1-like
chr19_+_35521699 1.77 ENST00000415950.3
SCN1B
sodium channel, voltage-gated, type I, beta subunit
chr10_-_97321112 1.77 ENST00000607232.1
ENST00000371227.4
ENST00000371249.2
ENST00000371247.2
ENST00000371246.2
ENST00000393949.1
ENST00000353505.5
ENST00000347291.4
SORBS1
sorbin and SH3 domain containing 1
chr6_+_155470243 1.77 ENST00000456877.2
ENST00000528391.2
TIAM2
T-cell lymphoma invasion and metastasis 2
chr5_+_43603229 1.73 ENST00000344920.4
ENST00000512996.2
NNT
nicotinamide nucleotide transhydrogenase
chr10_+_13142075 1.72 ENST00000378757.2
ENST00000430081.1
ENST00000378752.3
ENST00000378748.3
OPTN
optineurin
chr7_+_73507409 1.72 ENST00000538333.3
LIMK1
LIM domain kinase 1
chr11_+_34999328 1.71 ENST00000526309.1
PDHX
pyruvate dehydrogenase complex, component X
chr17_-_27467418 1.70 ENST00000528564.1
MYO18A
myosin XVIIIA
chr8_+_9413410 1.68 ENST00000520408.1
ENST00000310430.6
ENST00000522110.1
TNKS
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr8_-_123706338 1.68 ENST00000521608.1
RP11-973F15.1
long intergenic non-protein coding RNA 1151
chr1_-_154164534 1.67 ENST00000271850.7
ENST00000368530.2
TPM3
tropomyosin 3
chr10_+_13142225 1.67 ENST00000378747.3
OPTN
optineurin
chr14_+_90863327 1.67 ENST00000356978.4
CALM1
calmodulin 1 (phosphorylase kinase, delta)
chr6_-_24911195 1.64 ENST00000259698.4
FAM65B
family with sequence similarity 65, member B
chr7_+_80231466 1.63 ENST00000309881.7
ENST00000534394.1
CD36
CD36 molecule (thrombospondin receptor)
chr3_-_52869205 1.63 ENST00000446157.2
MUSTN1
musculoskeletal, embryonic nuclear protein 1
chr17_+_73028676 1.62 ENST00000581589.1
KCTD2
potassium channel tetramerization domain containing 2
chr17_+_42248063 1.60 ENST00000293414.1
ASB16
ankyrin repeat and SOCS box containing 16
chr7_+_134832808 1.60 ENST00000275767.3
TMEM140
transmembrane protein 140
chr1_-_9129895 1.60 ENST00000473209.1
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr11_-_1785139 1.58 ENST00000236671.2
CTSD
cathepsin D
chr11_+_123430948 1.57 ENST00000529432.1
ENST00000534764.1
GRAMD1B
GRAM domain containing 1B
chr1_+_22328144 1.55 ENST00000290122.3
ENST00000374663.1
CELA3A
chymotrypsin-like elastase family, member 3A
chr8_+_98788057 1.55 ENST00000517924.1
LAPTM4B
lysosomal protein transmembrane 4 beta
chr2_+_33701286 1.55 ENST00000403687.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr10_-_97321165 1.54 ENST00000306402.6
SORBS1
sorbin and SH3 domain containing 1
chr5_+_176692466 1.54 ENST00000508029.1
ENST00000503056.1
NSD1
nuclear receptor binding SET domain protein 1
chr12_+_652294 1.52 ENST00000322843.3
B4GALNT3
beta-1,4-N-acetyl-galactosaminyl transferase 3
chr15_-_52944231 1.52 ENST00000546305.2
FAM214A
family with sequence similarity 214, member A
chr17_+_33570055 1.52 ENST00000299977.4
ENST00000542451.1
ENST00000592325.1
SLFN5
schlafen family member 5
chr15_+_42696954 1.52 ENST00000337571.4
ENST00000569136.1
CAPN3
calpain 3, (p94)
chr19_-_46285646 1.51 ENST00000458663.2
DMPK
dystrophia myotonica-protein kinase
chr7_+_80275953 1.51 ENST00000538969.1
ENST00000544133.1
ENST00000433696.2
CD36
CD36 molecule (thrombospondin receptor)
chr10_+_24738355 1.51 ENST00000307544.6
KIAA1217
KIAA1217
chr15_+_42697018 1.49 ENST00000397204.4
CAPN3
calpain 3, (p94)
chr12_-_70093235 1.49 ENST00000266661.4
BEST3
bestrophin 3
chr17_+_4981535 1.48 ENST00000318833.3
ZFP3
ZFP3 zinc finger protein
chr9_-_35111420 1.46 ENST00000378557.1
FAM214B
family with sequence similarity 214, member B
chr8_-_66701319 1.45 ENST00000379419.4
PDE7A
phosphodiesterase 7A
chr3_+_49058444 1.45 ENST00000326925.6
ENST00000395458.2
NDUFAF3
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr4_+_77172847 1.45 ENST00000515604.1
ENST00000539752.1
ENST00000424749.2
FAM47E
FAM47E-STBD1
FAM47E
uncharacterized protein LOC100631383
FAM47E-STBD1 readthrough
family with sequence similarity 47, member E
chr18_-_74728998 1.45 ENST00000359645.3
ENST00000397875.3
ENST00000397869.3
ENST00000578193.1
ENST00000578873.1
ENST00000397866.4
ENST00000528160.1
ENST00000527041.1
ENST00000526111.1
ENST00000397865.5
ENST00000382582.3
MBP
myelin basic protein
chr15_-_40401062 1.44 ENST00000354670.4
ENST00000559701.1
ENST00000557870.1
ENST00000558774.1
BMF
Bcl2 modifying factor
chr18_-_59274139 1.43 ENST00000586949.1
RP11-879F14.2
RP11-879F14.2
chr3_+_35721106 1.43 ENST00000474696.1
ENST00000412048.1
ENST00000396482.2
ENST00000432682.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr1_+_14075903 1.43 ENST00000343137.4
ENST00000503842.1
ENST00000407521.3
ENST00000505823.1
PRDM2
PR domain containing 2, with ZNF domain
chr5_+_138209688 1.42 ENST00000518381.1
CTNNA1
catenin (cadherin-associated protein), alpha 1, 102kDa
chr11_-_62323702 1.42 ENST00000530285.1
AHNAK
AHNAK nucleoprotein
chr8_-_42396185 1.39 ENST00000518717.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr15_-_75748143 1.39 ENST00000568431.1
ENST00000568309.1
ENST00000568190.1
ENST00000570115.1
ENST00000564778.1
SIN3A
SIN3 transcription regulator family member A
chr14_-_69619823 1.38 ENST00000341516.5
DCAF5
DDB1 and CUL4 associated factor 5
chr16_-_75150665 1.38 ENST00000300051.4
ENST00000450168.2
LDHD
lactate dehydrogenase D
chr3_+_69134080 1.36 ENST00000273258.3
ARL6IP5
ADP-ribosylation-like factor 6 interacting protein 5
chr16_+_85204882 1.35 ENST00000574293.1
CTC-786C10.1
CTC-786C10.1
chr1_+_14075865 1.35 ENST00000413440.1
PRDM2
PR domain containing 2, with ZNF domain
chr15_+_42697065 1.34 ENST00000565559.1
CAPN3
calpain 3, (p94)
chr17_+_44679808 1.33 ENST00000571172.1
NSF
N-ethylmaleimide-sensitive factor
chr16_+_290181 1.32 ENST00000417499.1
ITFG3
integrin alpha FG-GAP repeat containing 3
chr15_+_42696992 1.32 ENST00000561817.1
CAPN3
calpain 3, (p94)
chr6_+_155334780 1.31 ENST00000538270.1
ENST00000535231.1
TIAM2
T-cell lymphoma invasion and metastasis 2
chr14_+_24584508 1.31 ENST00000559354.1
ENST00000560459.1
ENST00000559593.1
ENST00000396941.4
ENST00000396936.1
DCAF11
DDB1 and CUL4 associated factor 11
chr19_+_10527449 1.31 ENST00000592685.1
ENST00000380702.2
PDE4A
phosphodiesterase 4A, cAMP-specific
chr9_+_125795788 1.29 ENST00000373643.5
RABGAP1
RAB GTPase activating protein 1
chr13_+_76413852 1.29 ENST00000533809.2
LMO7
LIM domain 7
chr20_+_53092232 1.26 ENST00000395939.1
DOK5
docking protein 5
chr11_+_111783450 1.25 ENST00000537382.1
HSPB2
Homo sapiens heat shock 27kDa protein 2 (HSPB2), mRNA.
chr3_+_69134124 1.25 ENST00000478935.1
ARL6IP5
ADP-ribosylation-like factor 6 interacting protein 5
chr3_+_159570722 1.24 ENST00000482804.1
SCHIP1
schwannomin interacting protein 1
chr2_-_69870747 1.24 ENST00000409068.1
AAK1
AP2 associated kinase 1
chr10_-_62149433 1.23 ENST00000280772.2
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chrX_+_105445717 1.23 ENST00000372552.1
MUM1L1
melanoma associated antigen (mutated) 1-like 1
chr17_+_46918925 1.22 ENST00000502761.1
CALCOCO2
calcium binding and coiled-coil domain 2
chr2_+_136343943 1.22 ENST00000409606.1
R3HDM1
R3H domain containing 1
chr10_+_94594351 1.22 ENST00000371552.4
EXOC6
exocyst complex component 6
chr11_-_1507965 1.22 ENST00000329957.6
MOB2
MOB kinase activator 2
chr2_+_233562015 1.22 ENST00000427233.1
ENST00000373566.3
ENST00000373563.4
ENST00000428883.1
ENST00000456491.1
ENST00000409480.1
ENST00000421433.1
ENST00000425040.1
ENST00000430720.1
ENST00000409547.1
ENST00000423659.1
ENST00000409196.3
ENST00000409451.3
ENST00000429187.1
ENST00000440945.1
GIGYF2
GRB10 interacting GYF protein 2
chr17_-_21156578 1.22 ENST00000399011.2
ENST00000468196.1
C17orf103
chromosome 17 open reading frame 103
chr4_-_52904425 1.22 ENST00000535450.1
SGCB
sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
chr19_-_40324767 1.21 ENST00000601972.1
ENST00000430012.2
ENST00000323039.5
ENST00000348817.3
DYRK1B
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 17.4 GO:0007525 somatic muscle development(GO:0007525)
2.5 22.3 GO:0048630 skeletal muscle tissue growth(GO:0048630)
2.2 15.2 GO:0032971 regulation of muscle filament sliding(GO:0032971)
2.0 16.4 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
2.0 15.8 GO:0035995 detection of muscle stretch(GO:0035995)
1.5 8.9 GO:0018032 protein amidation(GO:0018032)
1.4 5.8 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
1.3 6.5 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
1.2 3.6 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
1.2 4.6 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.9 18.4 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.8 9.2 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.8 6.4 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.7 2.1 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.7 4.9 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.7 3.3 GO:0036115 fatty-acyl-CoA catabolic process(GO:0036115)
0.7 2.0 GO:1901076 positive regulation of engulfment of apoptotic cell(GO:1901076)
0.6 2.6 GO:0090095 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.6 3.5 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.6 8.8 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.6 2.2 GO:0030806 negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821) negative regulation of purine nucleotide catabolic process(GO:0033122)
0.5 1.6 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.5 5.1 GO:0006216 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.5 2.5 GO:0072709 cellular response to sorbitol(GO:0072709)
0.5 1.5 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.5 1.9 GO:1904647 response to rotenone(GO:1904647)
0.5 4.7 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.4 6.1 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.4 4.8 GO:0071313 cellular response to caffeine(GO:0071313)
0.4 3.0 GO:1990539 fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.4 1.7 GO:1903028 positive regulation of opsonization(GO:1903028)
0.4 1.7 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.4 2.0 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.4 1.2 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.4 2.6 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.4 1.9 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.4 5.1 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.4 1.5 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.3 1.7 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.3 1.0 GO:1904640 response to methionine(GO:1904640)
0.3 1.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.3 2.4 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.3 20.7 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.3 2.6 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.3 2.3 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.3 1.4 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.3 0.8 GO:0032903 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.3 3.4 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.3 3.1 GO:2000332 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.3 1.3 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.2 1.7 GO:0006740 NADPH regeneration(GO:0006740)
0.2 0.7 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.2 1.5 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.2 11.7 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.2 14.7 GO:0045214 sarcomere organization(GO:0045214)
0.2 2.8 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.2 8.4 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.2 1.8 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.2 1.5 GO:0048706 embryonic skeletal system development(GO:0048706)
0.2 0.6 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.2 8.7 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.2 0.9 GO:0035513 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.2 1.8 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.2 0.9 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.2 0.7 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.2 1.8 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.2 7.8 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.2 1.8 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.2 1.0 GO:0014826 cellular magnesium ion homeostasis(GO:0010961) vein smooth muscle contraction(GO:0014826)
0.2 2.4 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.2 1.1 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.2 0.9 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.2 1.5 GO:0034770 histone H4-K20 methylation(GO:0034770)
0.2 1.4 GO:0035494 SNARE complex disassembly(GO:0035494)
0.1 1.0 GO:1902306 negative regulation of sodium ion transmembrane transport(GO:1902306)
0.1 3.5 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 1.3 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.4 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.1 1.0 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086) chromatin maintenance(GO:0070827)
0.1 1.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 0.5 GO:1902954 regulation of early endosome to recycling endosome transport(GO:1902954)
0.1 0.5 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.1 0.4 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.1 0.8 GO:0072752 cellular response to rapamycin(GO:0072752)
0.1 0.6 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 1.9 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 1.8 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.1 0.8 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 1.1 GO:1903551 regulation of extracellular exosome assembly(GO:1903551)
0.1 7.2 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 0.7 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 0.9 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.1 0.5 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.1 1.9 GO:0014870 response to muscle inactivity(GO:0014870)
0.1 1.2 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 1.2 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.1 2.2 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 2.3 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.1 1.0 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.1 0.5 GO:0043686 co-translational protein modification(GO:0043686)
0.1 1.1 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.1 0.8 GO:0071918 urea transmembrane transport(GO:0071918)
0.1 1.1 GO:0035524 proline transmembrane transport(GO:0035524)
0.1 2.5 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.1 7.8 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 0.6 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 0.3 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
0.1 0.4 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.1 1.1 GO:0010815 bradykinin catabolic process(GO:0010815)
0.1 2.5 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 0.5 GO:0035936 testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
0.1 0.2 GO:0019087 transformation of host cell by virus(GO:0019087)
0.1 2.5 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.1 1.1 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.1 2.4 GO:0035988 chondrocyte proliferation(GO:0035988)
0.1 2.8 GO:0008340 determination of adult lifespan(GO:0008340)
0.1 0.3 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.1 0.5 GO:1902966 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.1 0.3 GO:0036292 DNA rewinding(GO:0036292)
0.1 0.8 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 1.4 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 0.3 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.1 0.4 GO:0031642 negative regulation of myelination(GO:0031642)
0.1 1.0 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 0.6 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.1 0.6 GO:0023021 termination of signal transduction(GO:0023021)
0.1 1.0 GO:0006824 cobalt ion transport(GO:0006824)
0.1 0.6 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 0.2 GO:1904784 NLRP1 inflammasome complex assembly(GO:1904784)
0.1 0.5 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.1 0.1 GO:0035284 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 0.5 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.1 10.3 GO:0043271 negative regulation of ion transport(GO:0043271)
0.1 4.5 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.1 4.7 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 2.8 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.1 0.9 GO:0030091 protein repair(GO:0030091)
0.1 2.2 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.1 0.3 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.1 1.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.2 GO:0050976 sensory perception of touch(GO:0050975) detection of mechanical stimulus involved in sensory perception of touch(GO:0050976)
0.1 2.8 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 1.4 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.1 1.7 GO:0030239 myofibril assembly(GO:0030239)
0.1 0.2 GO:0097476 spinal cord motor neuron migration(GO:0097476)
0.1 1.1 GO:0090050 peptidyl-lysine deacetylation(GO:0034983) positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 0.6 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 3.7 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1 0.5 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.1 0.8 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 2.2 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 2.0 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.5 GO:0048194 Golgi vesicle budding(GO:0048194)
0.1 2.3 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.1 0.7 GO:0018210 peptidyl-threonine phosphorylation(GO:0018107) peptidyl-threonine modification(GO:0018210)
0.1 0.8 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.1 0.5 GO:0001952 regulation of cell-matrix adhesion(GO:0001952)
0.1 2.4 GO:0097352 autophagosome maturation(GO:0097352)
0.1 0.3 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1 8.0 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 0.2 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 1.2 GO:0050879 multicellular organismal movement(GO:0050879) musculoskeletal movement(GO:0050881)
0.0 3.5 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.9 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.8 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 0.4 GO:0060017 parathyroid gland development(GO:0060017)
0.0 1.2 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.0 0.2 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 1.1 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 1.2 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 2.7 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.0 1.1 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.5 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.3 GO:1902022 lysine transport(GO:0015819) L-lysine transport(GO:1902022) L-lysine transmembrane transport(GO:1903401)
0.0 0.1 GO:0014732 skeletal muscle atrophy(GO:0014732)
0.0 1.1 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.0 0.3 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.0 0.7 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.5 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.6 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.4 GO:0030638 polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0 0.4 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.6 GO:0070932 histone H3 deacetylation(GO:0070932)
0.0 1.8 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.6 GO:0015747 urate transport(GO:0015747)
0.0 0.4 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 3.1 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 1.0 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 1.1 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.3 GO:0002062 chondrocyte differentiation(GO:0002062)
0.0 0.2 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 1.0 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.1 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.0 0.4 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.4 GO:0051775 response to redox state(GO:0051775)
0.0 0.6 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.5 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.2 GO:0045345 positive regulation of MHC class I biosynthetic process(GO:0045345)
0.0 0.7 GO:0045116 protein neddylation(GO:0045116)
0.0 0.2 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0 2.8 GO:0000045 autophagosome assembly(GO:0000045)
0.0 0.6 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.3 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.4 GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.0 1.7 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.4 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.3 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.2 GO:0038089 positive regulation of cell migration by vascular endothelial growth factor signaling pathway(GO:0038089)
0.0 0.4 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.5 GO:0033139 regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033139)
0.0 0.4 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.9 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.6 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.3 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 1.7 GO:0072413 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in mitotic cell cycle checkpoint(GO:0072413) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) signal transduction involved in mitotic DNA damage checkpoint(GO:1902402) signal transduction involved in mitotic DNA integrity checkpoint(GO:1902403)
0.0 0.8 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.3 GO:0060742 epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.0 0.5 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.0 4.8 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.1 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.3 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.5 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.4 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 0.1 GO:0060283 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.0 0.2 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0 0.8 GO:0031648 protein destabilization(GO:0031648)
0.0 0.5 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.1 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.0 0.1 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 1.2 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.3 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.2 GO:0051450 myoblast proliferation(GO:0051450)
0.0 0.4 GO:0008213 protein methylation(GO:0006479) protein alkylation(GO:0008213)
0.0 0.1 GO:0071440 regulation of histone H3-K14 acetylation(GO:0071440) positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.7 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.7 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 0.3 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.5 GO:0030262 cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.0 0.2 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 1.1 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 0.1 GO:0090678 response to mycophenolic acid(GO:0071505) cellular response to mycophenolic acid(GO:0071506) metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.0 0.3 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 15.2 GO:0016567 protein ubiquitination(GO:0016567)
0.0 0.9 GO:0032204 regulation of telomere maintenance(GO:0032204)
0.0 0.2 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.4 GO:0006835 dicarboxylic acid transport(GO:0006835)
0.0 0.0 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.2 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.4 GO:2000273 positive regulation of receptor activity(GO:2000273)
0.0 0.3 GO:0000470 maturation of 5.8S rRNA(GO:0000460) maturation of LSU-rRNA(GO:0000470)
0.0 2.8 GO:0007265 Ras protein signal transduction(GO:0007265)
0.0 0.4 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.5 GO:0043304 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.0 0.1 GO:0051966 regulation of synaptic transmission, glutamatergic(GO:0051966)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 19.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
1.0 27.8 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.9 5.1 GO:1990584 cardiac Troponin complex(GO:1990584)
0.5 25.0 GO:0005859 muscle myosin complex(GO:0005859)
0.5 3.6 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.5 3.3 GO:0005899 insulin receptor complex(GO:0005899)
0.5 5.5 GO:0016013 syntrophin complex(GO:0016013)
0.4 15.3 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.4 1.7 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.4 12.2 GO:0031143 pseudopodium(GO:0031143)
0.3 6.1 GO:0005861 troponin complex(GO:0005861)
0.3 8.5 GO:0033268 node of Ranvier(GO:0033268)
0.3 14.0 GO:0043034 costamere(GO:0043034)
0.3 14.2 GO:0031430 M band(GO:0031430)
0.3 59.7 GO:0031674 I band(GO:0031674)
0.3 7.9 GO:0031672 A band(GO:0031672)
0.3 2.0 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.2 14.6 GO:0030017 sarcomere(GO:0030017)
0.2 0.9 GO:1902912 pyruvate kinase complex(GO:1902912)
0.2 11.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.2 6.1 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.2 1.7 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.2 1.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.2 1.2 GO:1990635 proximal dendrite(GO:1990635)
0.2 0.5 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) glial limiting end-foot(GO:0097451)
0.1 2.0 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 0.5 GO:0071203 WASH complex(GO:0071203)
0.1 1.7 GO:0072357 glycogen granule(GO:0042587) PTW/PP1 phosphatase complex(GO:0072357)
0.1 1.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 1.9 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.1 1.6 GO:0016342 catenin complex(GO:0016342)
0.1 1.5 GO:0033269 internode region of axon(GO:0033269)
0.1 3.6 GO:0000242 pericentriolar material(GO:0000242)
0.1 2.9 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.6 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.1 1.0 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 0.3 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 6.1 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 0.8 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 0.8 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 3.7 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 0.9 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 1.0 GO:0030870 Mre11 complex(GO:0030870)
0.1 3.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.4 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 8.0 GO:0034707 chloride channel complex(GO:0034707)
0.1 7.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 1.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 9.2 GO:0005776 autophagosome(GO:0005776)
0.1 1.1 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.6 GO:0061574 ASAP complex(GO:0061574)
0.1 0.2 GO:0045160 myosin I complex(GO:0045160)
0.1 1.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 1.0 GO:0005869 dynactin complex(GO:0005869)
0.1 0.5 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 1.9 GO:0016580 Sin3 complex(GO:0016580)
0.1 0.4 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 0.3 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.8 GO:0031931 TORC1 complex(GO:0031931)
0.1 0.3 GO:0031310 intrinsic component of endosome membrane(GO:0031302) intrinsic component of vacuolar membrane(GO:0031310)
0.0 1.1 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 1.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 1.2 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.4 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 14.8 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.3 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.7 GO:0032039 integrator complex(GO:0032039)
0.0 6.7 GO:0035579 specific granule membrane(GO:0035579)
0.0 0.3 GO:0070545 PeBoW complex(GO:0070545)
0.0 3.5 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.0 1.1 GO:0030686 90S preribosome(GO:0030686)
0.0 8.9 GO:0032993 protein-DNA complex(GO:0032993)
0.0 3.4 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 1.0 GO:1904115 axon cytoplasm(GO:1904115)
0.0 1.2 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.4 GO:0012506 vesicle membrane(GO:0012506)
0.0 0.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.3 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.5 GO:0030914 STAGA complex(GO:0030914)
0.0 0.2 GO:0005761 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.4 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 1.5 GO:0005925 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925) cell-substrate junction(GO:0030055)
0.0 1.4 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.6 GO:0014704 intercalated disc(GO:0014704)
0.0 0.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.5 GO:0097440 apical dendrite(GO:0097440)
0.0 0.3 GO:0043596 nuclear replication fork(GO:0043596)
0.0 6.5 GO:0030027 lamellipodium(GO:0030027)
0.0 1.3 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 1.4 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.3 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.9 GO:0001772 immunological synapse(GO:0001772)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 1.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:0042599 lamellar body(GO:0042599)
0.0 0.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.3 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 0.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.4 GO:0042629 mast cell granule(GO:0042629)
0.0 0.2 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.8 GO:0031902 late endosome membrane(GO:0031902)
0.0 1.1 GO:0005815 microtubule organizing center(GO:0005815)
0.0 0.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 15.0 GO:0005730 nucleolus(GO:0005730)
0.0 0.6 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 14.7 GO:0032038 myosin II heavy chain binding(GO:0032038)
1.5 8.9 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
1.4 5.8 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
1.2 3.6 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
1.1 27.8 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
1.1 10.8 GO:0004687 myosin light chain kinase activity(GO:0004687)
1.0 2.9 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.9 7.4 GO:0050682 AF-2 domain binding(GO:0050682)
0.8 3.4 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.8 10.1 GO:0071253 connexin binding(GO:0071253)
0.8 16.4 GO:0008179 adenylate cyclase binding(GO:0008179)
0.7 5.1 GO:0031013 troponin I binding(GO:0031013)
0.6 1.7 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.6 5.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.6 9.5 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.5 8.1 GO:0031433 telethonin binding(GO:0031433)
0.5 63.9 GO:0008307 structural constituent of muscle(GO:0008307)
0.5 2.0 GO:0090556 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.5 4.6 GO:0031432 titin binding(GO:0031432)
0.5 1.4 GO:0016898 D-lactate dehydrogenase (cytochrome) activity(GO:0004458) oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor(GO:0016898)
0.4 1.3 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.4 3.0 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.4 7.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.4 1.1 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.3 1.5 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.3 1.2 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.3 6.0 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.3 6.4 GO:0005344 oxygen transporter activity(GO:0005344)
0.3 3.1 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.3 1.6 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.2 1.5 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.2 2.0 GO:0050816 phosphothreonine binding(GO:0050816)
0.2 0.7 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.2 4.7 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.2 2.7 GO:0031014 troponin T binding(GO:0031014)
0.2 1.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.2 1.5 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.2 0.8 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.2 1.0 GO:0031708 endothelin B receptor binding(GO:0031708)
0.2 1.7 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.2 5.3 GO:0044548 S100 protein binding(GO:0044548)
0.2 0.9 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.2 4.8 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.2 2.4 GO:0097016 L27 domain binding(GO:0097016)
0.2 1.3 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.2 10.9 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.2 13.5 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.2 0.7 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.2 1.4 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 1.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 2.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.9 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.4 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.1 0.4 GO:0070984 SET domain binding(GO:0070984)
0.1 2.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.4 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.1 0.9 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 1.9 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.1 2.6 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 0.4 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.1 0.8 GO:0015265 urea channel activity(GO:0015265)
0.1 0.8 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 8.8 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 1.0 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 3.1 GO:0017166 vinculin binding(GO:0017166)
0.1 1.4 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.1 0.4 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 0.9 GO:0043426 MRF binding(GO:0043426)
0.1 0.7 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 1.6 GO:0034594 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485) phosphatidylinositol trisphosphate phosphatase activity(GO:0034594)
0.1 0.6 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 0.4 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 3.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 3.7 GO:0070064 proline-rich region binding(GO:0070064)
0.1 3.9 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 2.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.4 GO:0034046 poly(G) binding(GO:0034046)
0.1 3.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 1.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 2.9 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 1.3 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.4 GO:0008494 translation activator activity(GO:0008494)
0.1 1.0 GO:0031419 cobalamin binding(GO:0031419)
0.1 1.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 1.0 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.1 2.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 9.3 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 0.6 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.1 0.3 GO:0098808 mRNA cap binding(GO:0098808)
0.1 1.8 GO:0097602 cullin family protein binding(GO:0097602)
0.1 4.3 GO:0005158 insulin receptor binding(GO:0005158)
0.1 0.4 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1 0.2 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.1 0.8 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 2.1 GO:0071949 FAD binding(GO:0071949)
0.1 0.4 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 2.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 1.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 0.3 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.6 GO:0071837 HMG box domain binding(GO:0071837)
0.1 2.6 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 0.7 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 1.1 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.5 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 1.1 GO:0008430 selenium binding(GO:0008430)
0.1 0.4 GO:0034511 U3 snoRNA binding(GO:0034511)
0.1 1.7 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 11.0 GO:0044325 ion channel binding(GO:0044325)
0.0 0.6 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 1.1 GO:0002162 dystroglycan binding(GO:0002162)
0.0 9.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 3.3 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 1.6 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 1.9 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.2 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.3 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.4 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.9 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 6.2 GO:0005254 chloride channel activity(GO:0005254)
0.0 4.4 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.2 GO:0033906 protein tyrosine kinase inhibitor activity(GO:0030292) hyaluronoglucuronidase activity(GO:0033906)
0.0 0.1 GO:0030395 lactose binding(GO:0030395)
0.0 0.5 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.7 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.5 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.3 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 5.1 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.4 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 1.1 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.7 GO:0004860 protein kinase inhibitor activity(GO:0004860) protein kinase regulator activity(GO:0019887)
0.0 0.5 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 1.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.5 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 4.7 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.1 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 1.0 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 11.8 GO:0008017 microtubule binding(GO:0008017)
0.0 1.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.3 GO:0032027 myosin light chain binding(GO:0032027)
0.0 1.7 GO:0043531 ADP binding(GO:0043531)
0.0 1.6 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.3 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 1.1 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.4 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.4 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.9 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.6 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.0 1.9 GO:0032813 tumor necrosis factor receptor superfamily binding(GO:0032813)
0.0 4.7 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 1.5 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 3.1 GO:0031072 heat shock protein binding(GO:0031072)
0.0 1.8 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.9 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 1.8 GO:0015631 tubulin binding(GO:0015631)
0.0 0.5 GO:0016887 ATPase activity(GO:0016887)
0.0 3.3 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.3 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 1.4 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 1.8 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.6 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.9 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0048156 tau protein binding(GO:0048156)
0.0 9.3 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.2 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.2 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.2 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 1.1 GO:0008047 enzyme activator activity(GO:0008047)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.2 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.4 GO:0004806 triglyceride lipase activity(GO:0004806)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 11.7 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.2 13.9 SIG CHEMOTAXIS Genes related to chemotaxis
0.2 16.4 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 2.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 1.1 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 4.2 PID MYC PATHWAY C-MYC pathway
0.1 4.5 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.1 1.1 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 3.8 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 2.9 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 9.0 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.8 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 4.0 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.7 PID RAS PATHWAY Regulation of Ras family activation
0.0 2.9 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 1.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 5.0 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.4 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 1.4 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 2.0 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.2 PID INSULIN PATHWAY Insulin Pathway
0.0 2.6 PID P53 REGULATION PATHWAY p53 pathway
0.0 2.8 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.0 PID ENDOTHELIN PATHWAY Endothelins
0.0 2.4 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 3.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 2.6 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.6 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 1.0 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.7 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 2.2 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.8 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.5 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.5 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 1.0 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.4 PID PDGFRB PATHWAY PDGFR-beta signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 27.8 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.6 45.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.4 7.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.2 12.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 6.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 4.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 3.0 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 2.0 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 6.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 0.9 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 1.3 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 3.6 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 2.8 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 3.1 REACTOME ANTIGEN PROCESSING CROSS PRESENTATION Genes involved in Antigen processing-Cross presentation
0.1 1.5 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 1.8 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 2.5 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 1.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 6.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 21.1 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 6.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 3.6 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 1.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.8 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 1.3 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.8 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 1.7 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 1.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.5 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.9 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 1.6 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.8 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.5 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.7 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 1.7 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 1.2 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 2.9 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 1.1 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 1.1 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.4 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 1.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.7 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 4.6 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.4 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.7 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.0 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 1.4 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.3 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.0 1.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.1 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.5 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.2 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.4 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.6 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.2 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.5 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.5 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.5 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.4 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.9 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling