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Illumina Body Map 2: averaged replicates

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Results for TFCP2L1

Z-value: 2.47

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Transcription factors associated with TFCP2L1

Gene Symbol Gene ID Gene Info
ENSG00000115112.7 TFCP2L1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TFCP2L1hg19_v2_chr2_-_122042770_1220427850.364.5e-02Click!

Activity profile of TFCP2L1 motif

Sorted Z-values of TFCP2L1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TFCP2L1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr20_+_55204351 3.69 ENST00000201031.2
TFAP2C
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr10_+_102505468 3.62 ENST00000361791.3
ENST00000355243.3
ENST00000428433.1
ENST00000370296.2
PAX2
paired box 2
chr10_+_102505954 3.54 ENST00000556085.1
ENST00000427256.1
PAX2
paired box 2
chr17_-_74023474 3.42 ENST00000301607.3
EVPL
envoplakin
chr1_-_153538011 3.39 ENST00000368707.4
S100A2
S100 calcium binding protein A2
chr17_-_46703826 3.32 ENST00000550387.1
ENST00000311177.5
HOXB9
homeobox B9
chr1_+_27668505 3.21 ENST00000318074.5
SYTL1
synaptotagmin-like 1
chr20_+_44098385 3.17 ENST00000217425.5
ENST00000339946.3
WFDC2
WAP four-disulfide core domain 2
chr17_-_74023291 3.15 ENST00000586740.1
EVPL
envoplakin
chr20_+_44098346 3.14 ENST00000372676.3
WFDC2
WAP four-disulfide core domain 2
chr21_-_31588365 3.07 ENST00000399899.1
CLDN8
claudin 8
chr15_+_41136216 3.03 ENST00000562057.1
ENST00000344051.4
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr20_-_52790512 3.03 ENST00000216862.3
CYP24A1
cytochrome P450, family 24, subfamily A, polypeptide 1
chr11_-_128737259 2.98 ENST00000440599.2
ENST00000392666.1
ENST00000324036.3
KCNJ1
potassium inwardly-rectifying channel, subfamily J, member 1
chr1_+_27189631 2.94 ENST00000339276.4
SFN
stratifin
chr9_-_127269661 2.81 ENST00000373588.4
NR5A1
nuclear receptor subfamily 5, group A, member 1
chr1_-_226129083 2.78 ENST00000420304.2
LEFTY2
left-right determination factor 2
chr1_-_153538292 2.76 ENST00000497140.1
ENST00000368708.3
S100A2
S100 calcium binding protein A2
chr1_-_226129189 2.73 ENST00000366820.5
LEFTY2
left-right determination factor 2
chr21_-_31588338 2.72 ENST00000286809.1
CLDN8
claudin 8
chr11_-_128737163 2.71 ENST00000324003.3
ENST00000392665.2
KCNJ1
potassium inwardly-rectifying channel, subfamily J, member 1
chr1_-_40782347 2.66 ENST00000417105.1
COL9A2
collagen, type IX, alpha 2
chr15_+_41136369 2.46 ENST00000563656.1
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr22_+_50986462 2.42 ENST00000395676.2
KLHDC7B
kelch domain containing 7B
chr20_+_9494987 2.40 ENST00000427562.2
ENST00000246070.2
LAMP5
lysosomal-associated membrane protein family, member 5
chr6_-_32731243 2.23 ENST00000427449.1
ENST00000411527.1
HLA-DQB2
major histocompatibility complex, class II, DQ beta 2
chr15_+_41136263 2.23 ENST00000568823.1
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr17_-_27038765 2.22 ENST00000581289.1
ENST00000301039.2
PROCA1
protein interacting with cyclin A1
chr6_-_31550192 2.19 ENST00000429299.2
ENST00000446745.2
LTB
lymphotoxin beta (TNF superfamily, member 3)
chr7_+_142423143 2.16 ENST00000390399.3
TRBV27
T cell receptor beta variable 27
chrX_-_51239425 2.14 ENST00000375992.3
NUDT11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr14_-_107170409 2.13 ENST00000390633.2
IGHV1-69
immunoglobulin heavy variable 1-69
chr6_-_32731299 2.10 ENST00000435145.2
ENST00000437316.2
HLA-DQB2
major histocompatibility complex, class II, DQ beta 2
chr1_-_207206092 2.05 ENST00000359470.5
ENST00000461135.2
C1orf116
chromosome 1 open reading frame 116
chr11_+_46403303 2.01 ENST00000407067.1
ENST00000395565.1
MDK
midkine (neurite growth-promoting factor 2)
chr1_-_111743285 2.00 ENST00000357640.4
DENND2D
DENN/MADD domain containing 2D
chr7_-_142240014 1.95 ENST00000390363.2
TRBV9
T cell receptor beta variable 9
chr12_-_48398104 1.94 ENST00000337299.6
ENST00000380518.3
COL2A1
collagen, type II, alpha 1
chr7_+_87563557 1.94 ENST00000439864.1
ENST00000412441.1
ENST00000398201.4
ENST00000265727.7
ENST00000315984.7
ENST00000398209.3
ADAM22
ADAM metallopeptidase domain 22
chr19_-_12251130 1.93 ENST00000418866.1
ENST00000600335.1
ZNF20
zinc finger protein 20
chr7_+_87563458 1.85 ENST00000398204.4
ADAM22
ADAM metallopeptidase domain 22
chr19_-_6591113 1.83 ENST00000423145.3
ENST00000245903.3
CD70
CD70 molecule
chr5_-_180018540 1.79 ENST00000292641.3
SCGB3A1
secretoglobin, family 3A, member 1
chr2_+_241544834 1.78 ENST00000319838.5
ENST00000403859.1
ENST00000438013.2
GPR35
G protein-coupled receptor 35
chr7_-_127671674 1.77 ENST00000478726.1
LRRC4
leucine rich repeat containing 4
chr2_-_20212422 1.75 ENST00000421259.2
ENST00000407540.3
MATN3
matrilin 3
chr10_-_61469837 1.73 ENST00000395348.3
SLC16A9
solute carrier family 16, member 9
chr11_+_46402744 1.71 ENST00000533952.1
MDK
midkine (neurite growth-promoting factor 2)
chrX_+_51075658 1.67 ENST00000356450.2
NUDT10
nudix (nucleoside diphosphate linked moiety X)-type motif 10
chr10_+_91589261 1.66 ENST00000448963.1
LINC00865
long intergenic non-protein coding RNA 865
chr5_+_52285144 1.66 ENST00000296585.5
ITGA2
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
chr19_-_46916805 1.64 ENST00000307522.3
CCDC8
coiled-coil domain containing 8
chr17_-_27038063 1.60 ENST00000439862.3
PROCA1
protein interacting with cyclin A1
chr2_+_219125714 1.59 ENST00000522678.1
ENST00000519574.1
ENST00000521462.1
GPBAR1
G protein-coupled bile acid receptor 1
chr11_+_46403194 1.57 ENST00000395569.4
ENST00000395566.4
MDK
midkine (neurite growth-promoting factor 2)
chr2_-_89385283 1.56 ENST00000390252.2
IGKV3-15
immunoglobulin kappa variable 3-15
chr19_+_1071203 1.55 ENST00000543365.1
HMHA1
histocompatibility (minor) HA-1
chr16_-_65155833 1.54 ENST00000566827.1
ENST00000394156.3
ENST00000562998.1
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr1_-_114696472 1.54 ENST00000393296.1
ENST00000369547.1
ENST00000610222.1
SYT6
synaptotagmin VI
chr1_-_155959280 1.54 ENST00000495070.2
ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr1_+_20617362 1.53 ENST00000375079.2
ENST00000289815.8
ENST00000375083.4
ENST00000289825.4
VWA5B1
von Willebrand factor A domain containing 5B1
chr17_+_7792101 1.53 ENST00000358181.4
ENST00000330494.7
CHD3
chromodomain helicase DNA binding protein 3
chr19_-_12251202 1.52 ENST00000334213.5
ZNF20
zinc finger protein 20
chr2_-_31361543 1.51 ENST00000349752.5
GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr17_-_1532106 1.50 ENST00000301335.5
ENST00000382147.4
SLC43A2
solute carrier family 43 (amino acid system L transporter), member 2
chr4_-_25865159 1.49 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr17_-_27278445 1.49 ENST00000268756.3
ENST00000584685.1
PHF12
PHD finger protein 12
chr2_-_99757876 1.47 ENST00000539964.1
ENST00000393482.3
TSGA10
testis specific, 10
chr1_-_155959853 1.46 ENST00000462460.2
ENST00000368316.1
ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr16_+_31366536 1.45 ENST00000562522.1
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr11_-_17555421 1.44 ENST00000526181.1
USH1C
Usher syndrome 1C (autosomal recessive, severe)
chr10_-_121296045 1.43 ENST00000392865.1
RGS10
regulator of G-protein signaling 10
chr14_-_106994333 1.41 ENST00000390624.2
IGHV3-48
immunoglobulin heavy variable 3-48
chr20_-_57089934 1.40 ENST00000439429.1
ENST00000371149.3
APCDD1L
adenomatosis polyposis coli down-regulated 1-like
chr5_-_169626104 1.37 ENST00000520275.1
ENST00000506431.2
CTB-27N1.1
CTB-27N1.1
chrX_+_69674943 1.37 ENST00000542398.1
DLG3
discs, large homolog 3 (Drosophila)
chr22_-_37545972 1.36 ENST00000216223.5
IL2RB
interleukin 2 receptor, beta
chr2_-_99757977 1.30 ENST00000355053.4
TSGA10
testis specific, 10
chr12_+_56324933 1.29 ENST00000549629.1
ENST00000555218.1
DGKA
diacylglycerol kinase, alpha 80kDa
chr4_+_40195262 1.28 ENST00000503941.1
RHOH
ras homolog family member H
chr19_+_12175535 1.28 ENST00000550826.1
ZNF844
zinc finger protein 844
chr22_-_20138302 1.27 ENST00000540078.1
ENST00000439765.2
AC006547.14
uncharacterized protein LOC388849
chr2_-_31361362 1.26 ENST00000430167.1
GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr17_+_15848231 1.26 ENST00000304222.2
ADORA2B
adenosine A2b receptor
chr12_+_56324756 1.25 ENST00000331886.5
ENST00000555090.1
DGKA
diacylglycerol kinase, alpha 80kDa
chr17_-_19619917 1.25 ENST00000325411.5
ENST00000350657.5
ENST00000433844.2
SLC47A2
solute carrier family 47 (multidrug and toxin extrusion), member 2
chr11_+_1856034 1.25 ENST00000341958.3
SYT8
synaptotagmin VIII
chr22_-_37823468 1.23 ENST00000402918.2
ELFN2
extracellular leucine-rich repeat and fibronectin type III domain containing 2
chr9_+_116111794 1.22 ENST00000374183.4
BSPRY
B-box and SPRY domain containing
chr12_+_41582103 1.22 ENST00000402685.2
PDZRN4
PDZ domain containing ring finger 4
chr10_-_99771079 1.20 ENST00000309155.3
CRTAC1
cartilage acidic protein 1
chr3_-_46930171 1.20 ENST00000593391.1
AC109583.1
Uncharacterized protein
chr11_-_7904464 1.20 ENST00000502624.2
ENST00000527565.1
RP11-35J10.5
RP11-35J10.5
chr19_+_20188830 1.19 ENST00000418063.2
ZNF90
zinc finger protein 90
chr12_+_49687425 1.18 ENST00000257860.4
PRPH
peripherin
chr1_-_1356628 1.14 ENST00000442470.1
ENST00000537107.1
ANKRD65
ankyrin repeat domain 65
chr19_-_6481776 1.14 ENST00000543576.1
ENST00000590173.1
ENST00000381480.2
DENND1C
DENN/MADD domain containing 1C
chr15_+_43886057 1.13 ENST00000441322.1
ENST00000413657.2
ENST00000453733.1
CKMT1B
creatine kinase, mitochondrial 1B
chr16_+_31366455 1.13 ENST00000268296.4
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr17_-_27278304 1.13 ENST00000577226.1
PHF12
PHD finger protein 12
chrX_+_133371077 1.13 ENST00000517294.1
ENST00000370809.4
CCDC160
coiled-coil domain containing 160
chr1_+_1361494 1.12 ENST00000378821.3
TMEM88B
transmembrane protein 88B
chr14_+_59104741 1.11 ENST00000395153.3
ENST00000335867.4
DACT1
dishevelled-binding antagonist of beta-catenin 1
chr16_-_86542455 1.11 ENST00000595886.1
ENST00000597578.1
ENST00000593604.1
FENDRR
FOXF1 adjacent non-coding developmental regulatory RNA
chr5_-_148758839 1.11 ENST00000261796.3
IL17B
interleukin 17B
chr1_+_26872324 1.10 ENST00000531382.1
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr12_+_49208234 1.10 ENST00000540990.1
CACNB3
calcium channel, voltage-dependent, beta 3 subunit
chr17_-_1531635 1.09 ENST00000571650.1
SLC43A2
solute carrier family 43 (amino acid system L transporter), member 2
chr1_-_43751276 1.09 ENST00000423420.1
C1orf210
chromosome 1 open reading frame 210
chr1_-_1356719 1.09 ENST00000520296.1
ANKRD65
ankyrin repeat domain 65
chr19_-_12405606 1.08 ENST00000356109.5
ZNF44
zinc finger protein 44
chr10_+_106400859 1.08 ENST00000369701.3
SORCS3
sortilin-related VPS10 domain containing receptor 3
chr20_+_30458431 1.06 ENST00000375938.4
ENST00000535842.1
ENST00000310998.4
ENST00000375921.2
TTLL9
tubulin tyrosine ligase-like family, member 9
chr11_-_119293903 1.05 ENST00000580275.1
THY1
Thy-1 cell surface antigen
chr20_-_30458019 1.05 ENST00000486996.1
ENST00000398084.2
DUSP15
dual specificity phosphatase 15
chr12_+_48178706 1.01 ENST00000599515.1
AC004466.1
Uncharacterized protein
chr19_-_12476443 1.00 ENST00000242804.4
ENST00000438182.1
ZNF442
zinc finger protein 442
chr19_-_49843539 1.00 ENST00000602554.1
ENST00000358234.4
CTC-301O7.4
CTC-301O7.4
chr2_+_98330009 0.99 ENST00000264972.5
ZAP70
zeta-chain (TCR) associated protein kinase 70kDa
chr7_+_63774321 0.99 ENST00000423484.2
ZNF736
zinc finger protein 736
chr3_-_123411191 0.99 ENST00000354792.5
ENST00000508240.1
MYLK
myosin light chain kinase
chr16_+_84328252 0.98 ENST00000219454.5
WFDC1
WAP four-disulfide core domain 1
chr5_-_131826457 0.98 ENST00000437654.1
ENST00000245414.4
IRF1
interferon regulatory factor 1
chr13_-_20806440 0.97 ENST00000400066.3
ENST00000400065.3
ENST00000356192.6
GJB6
gap junction protein, beta 6, 30kDa
chrX_-_138724677 0.96 ENST00000370573.4
ENST00000338585.6
ENST00000370576.4
MCF2
MCF.2 cell line derived transforming sequence
chr19_-_12405689 0.95 ENST00000355684.5
ZNF44
zinc finger protein 44
chr16_+_84328429 0.94 ENST00000568638.1
WFDC1
WAP four-disulfide core domain 1
chr19_+_19779589 0.94 ENST00000541458.1
ZNF101
zinc finger protein 101
chr6_+_31555045 0.94 ENST00000396101.3
ENST00000490742.1
LST1
leukocyte specific transcript 1
chr9_-_127269488 0.93 ENST00000455734.1
NR5A1
nuclear receptor subfamily 5, group A, member 1
chr20_-_30458432 0.93 ENST00000375966.4
ENST00000278979.3
DUSP15
dual specificity phosphatase 15
chr19_+_14693888 0.92 ENST00000547437.1
ENST00000397439.2
ENST00000417570.1
CLEC17A
C-type lectin domain family 17, member A
chr17_-_33775760 0.91 ENST00000534689.1
ENST00000532210.1
ENST00000526861.1
ENST00000531588.1
ENST00000285013.6
SLFN13
schlafen family member 13
chr1_-_161600990 0.91 ENST00000531221.1
FCGR3B
Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
chr12_+_56325231 0.89 ENST00000549368.1
DGKA
diacylglycerol kinase, alpha 80kDa
chr2_+_202937972 0.89 ENST00000541917.1
ENST00000295844.3
AC079354.1
uncharacterized protein KIAA2012
chr1_-_38512450 0.88 ENST00000373012.2
POU3F1
POU class 3 homeobox 1
chr11_+_67776012 0.88 ENST00000539229.1
ALDH3B1
aldehyde dehydrogenase 3 family, member B1
chr19_-_20844343 0.87 ENST00000595405.1
ZNF626
zinc finger protein 626
chr9_-_117150243 0.87 ENST00000374088.3
AKNA
AT-hook transcription factor
chr2_-_136875712 0.86 ENST00000241393.3
CXCR4
chemokine (C-X-C motif) receptor 4
chr11_-_119293872 0.86 ENST00000524970.1
THY1
Thy-1 cell surface antigen
chrX_-_138724994 0.85 ENST00000536274.1
MCF2
MCF.2 cell line derived transforming sequence
chr5_-_176923803 0.84 ENST00000506161.1
PDLIM7
PDZ and LIM domain 7 (enigma)
chr20_-_30458354 0.83 ENST00000428829.1
DUSP15
dual specificity phosphatase 15
chr1_+_55107449 0.83 ENST00000421030.2
ENST00000545244.1
ENST00000339553.5
ENST00000409996.1
ENST00000454855.2
MROH7
maestro heat-like repeat family member 7
chr20_-_62710832 0.82 ENST00000395042.1
RGS19
regulator of G-protein signaling 19
chr21_+_45773515 0.82 ENST00000397932.2
ENST00000300481.9
TRPM2
transient receptor potential cation channel, subfamily M, member 2
chr14_+_96671016 0.82 ENST00000542454.2
ENST00000554311.1
ENST00000306005.3
ENST00000539359.1
ENST00000553811.1
BDKRB2
RP11-404P21.8
bradykinin receptor B2
Uncharacterized protein
chr15_+_74218787 0.81 ENST00000261921.7
LOXL1
lysyl oxidase-like 1
chr1_-_46089718 0.80 ENST00000421127.2
ENST00000343901.2
ENST00000528266.1
CCDC17
coiled-coil domain containing 17
chr3_-_48956818 0.80 ENST00000408959.2
ARIH2OS
ariadne homolog 2 opposite strand
chr1_+_205225319 0.80 ENST00000329800.7
TMCC2
transmembrane and coiled-coil domain family 2
chr1_-_204329013 0.79 ENST00000272203.3
ENST00000414478.1
PLEKHA6
pleckstrin homology domain containing, family A member 6
chr1_-_161600942 0.78 ENST00000421702.2
FCGR3B
Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
chr5_-_176923846 0.78 ENST00000506537.1
PDLIM7
PDZ and LIM domain 7 (enigma)
chr12_-_45444873 0.76 ENST00000332700.6
DBX2
developing brain homeobox 2
chr1_-_43751230 0.76 ENST00000523677.1
C1orf210
chromosome 1 open reading frame 210
chr2_+_241564655 0.74 ENST00000407714.1
GPR35
G protein-coupled receptor 35
chrX_-_100183894 0.73 ENST00000328526.5
ENST00000372956.2
XKRX
XK, Kell blood group complex subunit-related, X-linked
chr5_+_139739772 0.72 ENST00000506757.2
ENST00000230993.6
ENST00000506545.1
ENST00000432095.2
ENST00000507527.1
SLC4A9
solute carrier family 4, sodium bicarbonate cotransporter, member 9
chr1_-_1142067 0.72 ENST00000379268.2
TNFRSF18
tumor necrosis factor receptor superfamily, member 18
chr1_-_46089639 0.72 ENST00000445048.2
CCDC17
coiled-coil domain containing 17
chr15_+_68871569 0.72 ENST00000566799.1
CORO2B
coronin, actin binding protein, 2B
chr15_-_65715401 0.72 ENST00000352385.2
IGDCC4
immunoglobulin superfamily, DCC subclass, member 4
chr18_-_2982869 0.72 ENST00000584915.1
LPIN2
lipin 2
chr9_-_117160738 0.72 ENST00000448674.1
RP11-9M16.2
RP11-9M16.2
chr4_-_174255536 0.71 ENST00000446922.2
HMGB2
high mobility group box 2
chr11_-_62380199 0.71 ENST00000419857.1
ENST00000394773.2
EML3
echinoderm microtubule associated protein like 3
chr11_-_117667806 0.71 ENST00000527706.1
ENST00000321322.6
DSCAML1
Down syndrome cell adhesion molecule like 1
chr19_-_12662240 0.71 ENST00000416136.1
ENST00000428311.1
ZNF564
ZNF709
zinc finger protein 564
ZNF709
chr1_+_2477831 0.70 ENST00000606645.1
RP3-395M20.12
RP3-395M20.12
chr12_+_52695617 0.70 ENST00000293525.5
KRT86
keratin 86
chr20_+_327413 0.70 ENST00000609179.1
NRSN2
neurensin 2
chr1_-_156217829 0.70 ENST00000356983.2
ENST00000335852.1
ENST00000340183.5
ENST00000540423.1
PAQR6
progestin and adipoQ receptor family member VI
chr1_-_1141927 0.69 ENST00000328596.6
ENST00000379265.5
TNFRSF18
tumor necrosis factor receptor superfamily, member 18
chr20_+_34680595 0.68 ENST00000406771.2
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr9_-_117150303 0.68 ENST00000312033.3
AKNA
AT-hook transcription factor
chr19_+_34112850 0.68 ENST00000591231.1
ENST00000434302.1
ENST00000438847.3
CHST8
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
chr11_+_133902667 0.67 ENST00000533091.1
ENST00000527712.1
RP11-713P17.3
RP11-713P17.3
chr2_+_71295733 0.67 ENST00000443938.2
ENST00000244204.6
NAGK
N-acetylglucosamine kinase
chr7_-_2883650 0.67 ENST00000544127.1
GNA12
guanine nucleotide binding protein (G protein) alpha 12
chr8_-_54755459 0.66 ENST00000524234.1
ENST00000521275.1
ENST00000396774.2
ATP6V1H
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr15_+_90234028 0.66 ENST00000268130.7
ENST00000560294.1
ENST00000558000.1
WDR93
WD repeat domain 93
chr16_+_680932 0.66 ENST00000319070.2
WFIKKN1
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1
chr12_-_120806960 0.65 ENST00000257552.2
MSI1
musashi RNA-binding protein 1
chr2_+_71295717 0.65 ENST00000418807.3
ENST00000443872.2
NAGK
N-acetylglucosamine kinase
chr19_+_41860047 0.65 ENST00000604123.1
TMEM91
transmembrane protein 91
chr5_-_160973649 0.64 ENST00000393959.1
ENST00000517547.1
GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2
chr2_+_71295766 0.64 ENST00000533981.1
NAGK
N-acetylglucosamine kinase
chr2_-_85890569 0.64 ENST00000494165.1
SFTPB
surfactant protein B
chr4_+_113970772 0.64 ENST00000504454.1
ENST00000394537.3
ENST00000357077.4
ENST00000264366.6
ANK2
ankyrin 2, neuronal
chr9_+_108424738 0.64 ENST00000334077.3
TAL2
T-cell acute lymphocytic leukemia 2
chr15_+_74466744 0.63 ENST00000560862.1
ENST00000395118.1
ISLR
immunoglobulin superfamily containing leucine-rich repeat
chr12_-_121342170 0.63 ENST00000353487.2
SPPL3
signal peptide peptidase like 3
chr17_+_75369167 0.63 ENST00000423034.2
SEPT9
septin 9
chr7_-_64467031 0.62 ENST00000394323.2
ERV3-1
endogenous retrovirus group 3, member 1
chr1_-_45272951 0.62 ENST00000372200.1
TCTEX1D4
Tctex1 domain containing 4
chr15_-_64665911 0.62 ENST00000606793.1
ENST00000561349.1
ENST00000560278.1
CTD-2116N17.1
Uncharacterized protein
chr14_-_69445793 0.62 ENST00000538545.2
ENST00000394419.4
ACTN1
actinin, alpha 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 7.2 GO:0035566 regulation of metanephros size(GO:0035566)
0.9 5.3 GO:0030421 defecation(GO:0030421)
0.8 3.0 GO:0042369 vitamin D catabolic process(GO:0042369)
0.7 3.7 GO:0007538 primary sex determination(GO:0007538)
0.6 3.8 GO:1901909 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.6 2.9 GO:0010481 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.6 1.7 GO:0033341 regulation of collagen binding(GO:0033341)
0.5 1.9 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.4 3.5 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.4 2.5 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.4 2.0 GO:0006051 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.4 1.4 GO:1904106 protein localization to microvillus(GO:1904106)
0.4 3.2 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.3 1.3 GO:0002545 chronic inflammatory response to non-antigenic stimulus(GO:0002545) regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002880)
0.3 1.5 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.3 7.7 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.3 1.1 GO:2000176 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.2 1.6 GO:0038183 bile acid signaling pathway(GO:0038183)
0.2 1.4 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.2 0.8 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.2 0.8 GO:0018277 protein deamination(GO:0018277)
0.2 0.6 GO:0097534 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535) regulation of positive thymic T cell selection(GO:1902232)
0.2 1.9 GO:0060174 limb bud formation(GO:0060174)
0.2 1.0 GO:0043366 beta selection(GO:0043366)
0.2 0.5 GO:2001037 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.2 0.5 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.2 1.1 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.2 5.8 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.2 0.5 GO:0046103 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.1 1.3 GO:0046618 drug export(GO:0046618)
0.1 0.6 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 0.6 GO:1903412 response to bile acid(GO:1903412)
0.1 1.1 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 1.0 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 4.7 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.1 0.4 GO:0071314 cellular response to cocaine(GO:0071314)
0.1 0.5 GO:1905071 occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.1 0.3 GO:0042938 dipeptide transport(GO:0042938)
0.1 0.9 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.1 1.2 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.1 5.6 GO:0010107 potassium ion import(GO:0010107)
0.1 0.2 GO:1904815 negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.1 0.2 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.1 6.9 GO:0018149 peptide cross-linking(GO:0018149)
0.1 1.7 GO:0046415 urate metabolic process(GO:0046415)
0.1 3.5 GO:0050482 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.1 1.5 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.1 0.3 GO:0060166 olfactory pit development(GO:0060166)
0.1 0.6 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1 0.8 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.1 3.4 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.1 1.1 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.1 0.2 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205)
0.1 0.1 GO:0021767 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373)
0.1 1.2 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.1 0.4 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.1 0.4 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 2.8 GO:0048713 regulation of oligodendrocyte differentiation(GO:0048713)
0.1 1.6 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.1 1.1 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.1 0.5 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.1 2.1 GO:0051764 actin crosslink formation(GO:0051764)
0.1 0.4 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1 4.7 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 1.1 GO:1900452 regulation of long term synaptic depression(GO:1900452)
0.0 0.3 GO:0030047 actin modification(GO:0030047)
0.0 0.4 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 3.0 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.4 GO:0006477 protein sulfation(GO:0006477)
0.0 0.3 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.4 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.4 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244) negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0 2.3 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 1.4 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 0.2 GO:0010847 regulation of chromatin assembly(GO:0010847) protein auto-ADP-ribosylation(GO:0070213)
0.0 0.6 GO:0021794 thalamus development(GO:0021794)
0.0 0.6 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.3 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 5.1 GO:0030449 regulation of complement activation(GO:0030449)
0.0 0.9 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 4.3 GO:0031295 T cell costimulation(GO:0031295)
0.0 1.0 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 1.1 GO:0043401 steroid hormone mediated signaling pathway(GO:0043401)
0.0 0.3 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.6 GO:0034776 response to histamine(GO:0034776) cellular response to histamine(GO:0071420)
0.0 0.4 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.5 GO:0006527 arginine catabolic process(GO:0006527)
0.0 1.5 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.2 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.7 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.2 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.5 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 2.8 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.0 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.5 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.4 GO:1902373 negative regulation of mRNA catabolic process(GO:1902373)
0.0 0.3 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 6.2 GO:0043542 endothelial cell migration(GO:0043542)
0.0 0.3 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 3.1 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 2.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.2 GO:0006294 nucleotide-excision repair, preincision complex assembly(GO:0006294)
0.0 0.1 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.0 1.3 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 2.8 GO:1990823 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.3 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.5 GO:0097186 amelogenesis(GO:0097186)
0.0 0.8 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 1.9 GO:0061045 negative regulation of wound healing(GO:0061045)
0.0 1.6 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 1.4 GO:0050672 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.0 0.5 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 1.0 GO:0051602 response to electrical stimulus(GO:0051602)
0.0 1.0 GO:0090280 positive regulation of calcium ion import(GO:0090280)
0.0 0.5 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.7 GO:0010762 regulation of fibroblast migration(GO:0010762)
0.0 0.5 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 1.8 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.4 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.1 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0 2.4 GO:0030879 mammary gland development(GO:0030879)
0.0 0.4 GO:0015695 organic cation transport(GO:0015695)
0.0 0.3 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 1.5 GO:0032508 DNA duplex unwinding(GO:0032508)
0.0 4.4 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.3 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.5 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 2.3 GO:0046546 male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.0 0.1 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.2 GO:0001502 cartilage condensation(GO:0001502)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.7 GO:0005594 collagen type IX trimer(GO:0005594)
0.3 3.4 GO:0032584 growth cone membrane(GO:0032584)
0.3 1.7 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.2 1.6 GO:1990393 3M complex(GO:1990393)
0.2 4.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 5.9 GO:0034451 centriolar satellite(GO:0034451)
0.1 0.4 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.1 5.6 GO:0030057 desmosome(GO:0030057)
0.1 1.9 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.6 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.1 0.6 GO:0019031 viral envelope(GO:0019031) viral membrane(GO:0036338)
0.1 4.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.7 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.1 3.2 GO:0031528 microvillus membrane(GO:0031528)
0.1 1.5 GO:0005916 fascia adherens(GO:0005916)
0.1 2.6 GO:0016580 Sin3 complex(GO:0016580)
0.1 1.9 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 0.2 GO:0097454 Schwann cell microvillus(GO:0097454)
0.1 0.4 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 1.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.6 GO:0097486 alveolar lamellar body(GO:0097208) multivesicular body lumen(GO:0097486)
0.1 3.1 GO:0008305 integrin complex(GO:0008305)
0.0 1.5 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.4 GO:0031985 Golgi cisterna(GO:0031985)
0.0 1.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 4.7 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.5 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 6.1 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.3 GO:1990769 proximal neuron projection(GO:1990769)
0.0 1.0 GO:0005922 connexon complex(GO:0005922)
0.0 0.6 GO:0071439 clathrin complex(GO:0071439)
0.0 2.3 GO:0001772 immunological synapse(GO:0001772)
0.0 2.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.0 GO:0031105 septin complex(GO:0031105)
0.0 5.9 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.5 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.3 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 1.4 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 2.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 2.6 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 3.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.6 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.1 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.3 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.4 GO:0071437 invadopodium(GO:0071437)
0.0 0.5 GO:0032040 small-subunit processome(GO:0032040)
0.0 1.4 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.6 GO:0031430 M band(GO:0031430)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 6.3 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.7 2.9 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.6 3.8 GO:0034431 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.6 5.7 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.6 3.0 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.5 2.0 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.4 4.6 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.4 6.6 GO:0019215 intermediate filament binding(GO:0019215)
0.3 7.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.3 0.8 GO:0004947 bradykinin receptor activity(GO:0004947)
0.3 1.4 GO:0019976 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.3 4.3 GO:0032395 MHC class II receptor activity(GO:0032395)
0.2 1.2 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.2 1.6 GO:0038181 bile acid receptor activity(GO:0038181)
0.2 3.4 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.2 1.3 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.2 1.7 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.2 1.9 GO:0034235 GPI anchor binding(GO:0034235)
0.2 0.5 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 2.8 GO:0019864 IgG binding(GO:0019864)
0.1 1.2 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.1 0.9 GO:0042806 fucose binding(GO:0042806)
0.1 0.5 GO:0052596 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.1 3.0 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.6 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.5 GO:0070051 fibrinogen binding(GO:0070051)
0.1 1.1 GO:0070097 delta-catenin binding(GO:0070097)
0.1 2.6 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 1.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.6 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.1 1.3 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 4.0 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.5 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.5 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 1.2 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.1 2.8 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 3.8 GO:0004623 phospholipase A2 activity(GO:0004623)
0.1 10.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 2.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.5 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.3 GO:0015563 uptake transmembrane transporter activity(GO:0015563)
0.1 0.6 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.4 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 2.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.6 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 4.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.3 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.0 3.5 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 2.6 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 1.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 1.5 GO:0017166 vinculin binding(GO:0017166)
0.0 1.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 2.8 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.4 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.5 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.8 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 4.9 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 1.4 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.4 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.5 GO:0015386 potassium:proton antiporter activity(GO:0015386) potassium ion antiporter activity(GO:0022821)
0.0 2.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 3.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.8 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 2.4 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 1.5 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.2 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0 0.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.5 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.4 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.0 0.7 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 5.0 GO:0008083 growth factor activity(GO:0008083)
0.0 1.0 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.5 GO:0001055 RNA polymerase I activity(GO:0001054) RNA polymerase II activity(GO:0001055)
0.0 0.1 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.7 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 4.7 GO:0003823 antigen binding(GO:0003823)
0.0 0.3 GO:0045159 myosin II binding(GO:0045159)
0.0 0.7 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 3.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.1 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 2.9 GO:0005125 cytokine activity(GO:0005125)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.6 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.5 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 1.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 1.8 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.9 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 1.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.3 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 1.8 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 1.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 16.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 7.9 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 4.7 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.1 4.6 NABA COLLAGENS Genes encoding collagen proteins
0.1 3.2 PID REELIN PATHWAY Reelin signaling pathway
0.1 2.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.5 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.4 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 1.8 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.9 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.0 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.1 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 2.9 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.2 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.6 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.4 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 1.4 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.0 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.0 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.6 PID FGF PATHWAY FGF signaling pathway
0.0 5.8 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 1.5 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.8 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.3 PID CMYB PATHWAY C-MYB transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 0.9 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 5.8 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 1.7 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 5.8 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.1 6.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 3.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 3.0 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 1.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 5.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 1.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.0 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.8 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 1.0 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 2.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.7 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 1.2 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 1.2 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.8 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 3.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.1 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 2.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 2.4 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 1.4 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.5 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.5 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 1.1 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 8.9 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.7 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.5 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.2 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.2 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 1.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 2.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.4 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 1.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell