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Illumina Body Map 2: averaged replicates

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Results for TP73

Z-value: 1.26

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Transcription factors associated with TP73

Gene Symbol Gene ID Gene Info
TP73
ENSG00000078900.10 tumor protein p73

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TP73hg19_v2_chr1_+_3598871_35989300.421.6e-02Click!

Activity profile of TP73 motif

Sorted Z-values of TP73 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_222846 2.81 ENST00000251595.6
ENST00000397806.1
HBA2
hemoglobin, alpha 2
chr7_-_27213893 2.73 ENST00000283921.4
HOXA10
homeobox A10
chr14_+_22217447 2.45 ENST00000390427.3
TRAV5
T cell receptor alpha variable 5
chr14_-_25045446 2.19 ENST00000216336.2
CTSG
cathepsin G
chr7_-_128045984 1.97 ENST00000470772.1
ENST00000480861.1
ENST00000496200.1
IMPDH1
IMP (inosine 5'-monophosphate) dehydrogenase 1
chr7_-_100171270 1.95 ENST00000538735.1
SAP25
Sin3A-associated protein, 25kDa
chr14_+_75746340 1.91 ENST00000555686.1
ENST00000555672.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr15_+_75498355 1.75 ENST00000567617.1
C15orf39
chromosome 15 open reading frame 39
chr4_-_87770416 1.72 ENST00000273905.6
SLC10A6
solute carrier family 10 (sodium/bile acid cotransporter), member 6
chr15_+_41136216 1.70 ENST00000562057.1
ENST00000344051.4
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr15_+_75498739 1.63 ENST00000565074.1
C15orf39
chromosome 15 open reading frame 39
chr2_+_128293323 1.58 ENST00000389524.4
ENST00000428314.1
MYO7B
myosin VIIB
chr14_+_75745477 1.55 ENST00000303562.4
ENST00000554617.1
ENST00000554212.1
ENST00000535987.1
ENST00000555242.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr14_+_22554680 1.50 ENST00000390451.2
TRAV23DV6
T cell receptor alpha variable 23/delta variable 6
chr2_+_114163945 1.47 ENST00000453673.3
IGKV1OR2-108
immunoglobulin kappa variable 1/OR2-108 (non-functional)
chr17_-_42452063 1.46 ENST00000588098.1
ITGA2B
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
chr14_+_95982451 1.44 ENST00000554161.1
RP11-1070N10.3
Uncharacterized protein
chr14_+_52780998 1.40 ENST00000557436.1
PTGER2
prostaglandin E receptor 2 (subtype EP2), 53kDa
chr15_+_41136586 1.32 ENST00000431806.1
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr6_-_46703069 1.29 ENST00000538237.1
ENST00000274793.7
PLA2G7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr15_+_41136369 1.27 ENST00000563656.1
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr15_+_74466744 1.21 ENST00000560862.1
ENST00000395118.1
ISLR
immunoglobulin superfamily containing leucine-rich repeat
chr17_+_43318434 1.21 ENST00000587489.1
FMNL1
formin-like 1
chr15_+_41136263 1.13 ENST00000568823.1
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr17_+_37356586 1.09 ENST00000579260.1
ENST00000582193.1
RPL19
ribosomal protein L19
chr17_+_37356528 1.06 ENST00000225430.4
RPL19
ribosomal protein L19
chr10_-_105212141 1.00 ENST00000369788.3
CALHM2
calcium homeostasis modulator 2
chr12_-_57505121 1.00 ENST00000538913.2
ENST00000537215.2
ENST00000454075.3
ENST00000554825.1
ENST00000553275.1
ENST00000300134.3
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr10_-_105212059 0.99 ENST00000260743.5
CALHM2
calcium homeostasis modulator 2
chr19_+_45254529 0.99 ENST00000444487.1
BCL3
B-cell CLL/lymphoma 3
chr14_-_75078725 0.97 ENST00000556690.1
LTBP2
latent transforming growth factor beta binding protein 2
chr3_-_185538849 0.96 ENST00000421047.2
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr1_+_47137445 0.96 ENST00000569393.1
ENST00000334122.4
ENST00000415500.1
TEX38
testis expressed 38
chr1_-_160832490 0.95 ENST00000322302.7
ENST00000368033.3
CD244
CD244 molecule, natural killer cell receptor 2B4
chr2_-_26864228 0.94 ENST00000288861.4
CIB4
calcium and integrin binding family member 4
chr17_+_37356555 0.93 ENST00000579374.1
RPL19
ribosomal protein L19
chr1_-_160832642 0.92 ENST00000368034.4
CD244
CD244 molecule, natural killer cell receptor 2B4
chr6_-_46703430 0.91 ENST00000537365.1
PLA2G7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr22_-_37976082 0.91 ENST00000215886.4
LGALS2
lectin, galactoside-binding, soluble, 2
chr9_-_130517309 0.90 ENST00000414380.1
SH2D3C
SH2 domain containing 3C
chr8_+_37654693 0.88 ENST00000412232.2
GPR124
G protein-coupled receptor 124
chr12_+_102271436 0.88 ENST00000544152.1
DRAM1
DNA-damage regulated autophagy modulator 1
chr1_+_47137544 0.87 ENST00000564373.1
TEX38
testis expressed 38
chr3_+_136676851 0.83 ENST00000309741.5
IL20RB
interleukin 20 receptor beta
chr9_+_131445703 0.83 ENST00000454747.1
SET
SET nuclear oncogene
chr11_+_65154070 0.81 ENST00000317568.5
ENST00000531296.1
ENST00000533782.1
ENST00000355991.5
ENST00000416776.2
ENST00000526201.1
FRMD8
FERM domain containing 8
chr8_+_37654424 0.80 ENST00000315215.7
GPR124
G protein-coupled receptor 124
chr20_+_35504522 0.79 ENST00000602922.1
ENST00000217320.3
TLDC2
TBC/LysM-associated domain containing 2
chr3_+_136676707 0.77 ENST00000329582.4
IL20RB
interleukin 20 receptor beta
chr10_+_47746929 0.75 ENST00000340243.6
ENST00000374277.5
ENST00000449464.2
ENST00000538825.1
ENST00000335083.5
ANXA8L2
AL603965.1
annexin A8-like 2
Protein LOC100996760
chr17_+_73750699 0.75 ENST00000584939.1
ITGB4
integrin, beta 4
chr17_+_54230819 0.74 ENST00000318698.2
ENST00000566473.2
ANKFN1
ankyrin-repeat and fibronectin type III domain containing 1
chr17_+_7792101 0.74 ENST00000358181.4
ENST00000330494.7
CHD3
chromodomain helicase DNA binding protein 3
chr20_+_48807351 0.72 ENST00000303004.3
CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr9_-_20382446 0.72 ENST00000380321.1
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr6_-_112194484 0.69 ENST00000518295.1
ENST00000484067.2
ENST00000229470.5
ENST00000356013.2
ENST00000368678.4
ENST00000523238.1
ENST00000354650.3
FYN
FYN oncogene related to SRC, FGR, YES
chr14_-_36983034 0.69 ENST00000518529.2
SFTA3
surfactant associated 3
chr9_+_6758024 0.68 ENST00000442236.2
KDM4C
lysine (K)-specific demethylase 4C
chr18_-_53253323 0.68 ENST00000540999.1
ENST00000563888.2
TCF4
transcription factor 4
chr1_-_160832670 0.66 ENST00000368032.2
CD244
CD244 molecule, natural killer cell receptor 2B4
chr17_-_42200996 0.66 ENST00000587135.1
ENST00000225983.6
ENST00000393622.2
ENST00000588703.1
HDAC5
histone deacetylase 5
chr17_-_80059726 0.62 ENST00000583053.1
CCDC57
coiled-coil domain containing 57
chr11_+_75479850 0.61 ENST00000376262.3
ENST00000604733.1
DGAT2
diacylglycerol O-acyltransferase 2
chrX_-_38186811 0.60 ENST00000318842.7
RPGR
retinitis pigmentosa GTPase regulator
chr19_-_35981358 0.58 ENST00000484218.2
ENST00000338897.3
KRTDAP
keratinocyte differentiation-associated protein
chr9_+_6757634 0.56 ENST00000543771.1
ENST00000401787.3
ENST00000381306.3
ENST00000381309.3
KDM4C
lysine (K)-specific demethylase 4C
chr14_-_105531759 0.55 ENST00000329797.3
ENST00000539291.2
ENST00000392585.2
GPR132
G protein-coupled receptor 132
chr9_+_6758109 0.53 ENST00000536108.1
KDM4C
lysine (K)-specific demethylase 4C
chr1_-_26197744 0.53 ENST00000374296.3
PAQR7
progestin and adipoQ receptor family member VII
chr20_-_62203808 0.53 ENST00000467148.1
HELZ2
helicase with zinc finger 2, transcriptional coactivator
chr1_-_236228417 0.53 ENST00000264187.6
NID1
nidogen 1
chr14_+_23006547 0.52 ENST00000390530.1
TRAJ7
T cell receptor alpha joining 7
chr16_+_8891670 0.48 ENST00000268261.4
ENST00000539622.1
ENST00000569958.1
ENST00000537352.1
PMM2
phosphomannomutase 2
chr9_+_36169380 0.47 ENST00000335119.2
CCIN
calicin
chr2_+_220283091 0.47 ENST00000373960.3
DES
desmin
chr1_-_236228403 0.47 ENST00000366595.3
NID1
nidogen 1
chr20_-_49253425 0.46 ENST00000045083.2
FAM65C
family with sequence similarity 65, member C
chr10_-_47173994 0.46 ENST00000414655.2
ENST00000545298.1
ENST00000359178.4
ENST00000358140.4
ENST00000503031.1
ANXA8L1
LINC00842
annexin A8-like 1
long intergenic non-protein coding RNA 842
chr4_+_6717842 0.45 ENST00000320776.3
BLOC1S4
biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino
chr2_+_95940186 0.43 ENST00000403131.2
ENST00000317668.4
ENST00000317620.9
PROM2
prominin 2
chrX_+_77166172 0.43 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATP7A
ATPase, Cu++ transporting, alpha polypeptide
chr10_+_70661014 0.42 ENST00000373585.3
DDX50
DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
chr18_-_53253000 0.42 ENST00000566514.1
TCF4
transcription factor 4
chr9_+_133223932 0.41 ENST00000420499.2
HMCN2
hemicentin 2
chr19_+_41856816 0.40 ENST00000539627.1
TMEM91
transmembrane protein 91
chr17_-_40835076 0.39 ENST00000591765.1
CCR10
chemokine (C-C motif) receptor 10
chr19_+_45281118 0.39 ENST00000270279.3
ENST00000341505.4
CBLC
Cbl proto-oncogene C, E3 ubiquitin protein ligase
chr10_-_79686284 0.38 ENST00000372391.2
ENST00000372388.2
DLG5
discs, large homolog 5 (Drosophila)
chr5_-_156593273 0.38 ENST00000302938.4
FAM71B
family with sequence similarity 71, member B
chrX_-_38186775 0.37 ENST00000339363.3
ENST00000309513.3
ENST00000338898.3
ENST00000342811.3
ENST00000378505.2
RPGR
retinitis pigmentosa GTPase regulator
chr10_-_99185798 0.35 ENST00000439965.2
AL355490.1
LOC644215 protein; Uncharacterized protein
chr18_-_53253112 0.35 ENST00000568673.1
ENST00000562847.1
ENST00000568147.1
TCF4
transcription factor 4
chr15_+_64680003 0.34 ENST00000261884.3
TRIP4
thyroid hormone receptor interactor 4
chr19_+_44037546 0.34 ENST00000601282.1
ZNF575
zinc finger protein 575
chr22_+_39966758 0.34 ENST00000407673.1
ENST00000401624.1
ENST00000404898.1
ENST00000402142.3
ENST00000336649.4
ENST00000400164.3
CACNA1I
calcium channel, voltage-dependent, T type, alpha 1I subunit
chr20_-_52790512 0.33 ENST00000216862.3
CYP24A1
cytochrome P450, family 24, subfamily A, polypeptide 1
chr16_+_84178874 0.33 ENST00000378553.5
DNAAF1
dynein, axonemal, assembly factor 1
chr1_-_78444776 0.33 ENST00000370767.1
ENST00000421641.1
FUBP1
far upstream element (FUSE) binding protein 1
chr19_-_19626838 0.30 ENST00000360913.3
TSSK6
testis-specific serine kinase 6
chr13_-_48877795 0.30 ENST00000436963.1
ENST00000433480.2
LINC00441
long intergenic non-protein coding RNA 441
chr19_-_39226045 0.30 ENST00000597987.1
ENST00000595177.1
CAPN12
calpain 12
chr5_-_141060389 0.30 ENST00000504448.1
ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr2_-_232328867 0.28 ENST00000453992.1
ENST00000417652.1
ENST00000454824.1
NCL
nucleolin
chr22_+_29168652 0.28 ENST00000249064.4
ENST00000444523.1
ENST00000448492.2
ENST00000421503.2
CCDC117
coiled-coil domain containing 117
chr19_+_41620335 0.28 ENST00000331105.2
CYP2F1
cytochrome P450, family 2, subfamily F, polypeptide 1
chr5_+_78532003 0.28 ENST00000396137.4
JMY
junction mediating and regulatory protein, p53 cofactor
chr20_-_52790055 0.27 ENST00000395955.3
CYP24A1
cytochrome P450, family 24, subfamily A, polypeptide 1
chr1_-_78444738 0.27 ENST00000436586.2
ENST00000370768.2
FUBP1
far upstream element (FUSE) binding protein 1
chr11_+_60197040 0.27 ENST00000300190.2
MS4A5
membrane-spanning 4-domains, subfamily A, member 5
chr2_+_95940220 0.24 ENST00000542147.1
PROM2
prominin 2
chr7_-_2883928 0.24 ENST00000275364.3
GNA12
guanine nucleotide binding protein (G protein) alpha 12
chr5_+_38258511 0.24 ENST00000354891.3
ENST00000322350.5
EGFLAM
EGF-like, fibronectin type III and laminin G domains
chr3_-_151160938 0.23 ENST00000489791.1
IGSF10
immunoglobulin superfamily, member 10
chr11_-_75062829 0.23 ENST00000393505.4
ARRB1
arrestin, beta 1
chr6_+_35995552 0.23 ENST00000468133.1
MAPK14
mitogen-activated protein kinase 14
chr5_+_119799927 0.22 ENST00000407149.2
ENST00000379551.2
PRR16
proline rich 16
chr1_-_241799232 0.21 ENST00000366553.1
CHML
choroideremia-like (Rab escort protein 2)
chr6_+_35995531 0.19 ENST00000229794.4
MAPK14
mitogen-activated protein kinase 14
chr21_+_43442100 0.19 ENST00000455701.1
ENST00000596595.1
ZNF295-AS1
ZNF295 antisense RNA 1
chr7_-_2883650 0.18 ENST00000544127.1
GNA12
guanine nucleotide binding protein (G protein) alpha 12
chr11_+_65686952 0.18 ENST00000527119.1
DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr16_-_68000717 0.17 ENST00000541864.2
SLC12A4
solute carrier family 12 (potassium/chloride transporter), member 4
chr9_-_128003606 0.17 ENST00000324460.6
HSPA5
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
chr17_-_39023462 0.17 ENST00000251643.4
KRT12
keratin 12
chr6_-_33256664 0.17 ENST00000444176.1
WDR46
WD repeat domain 46
chr7_+_141618617 0.16 ENST00000548136.1
OR9A4
olfactory receptor, family 9, subfamily A, member 4
chr16_+_67197288 0.15 ENST00000264009.8
ENST00000421453.1
HSF4
heat shock transcription factor 4
chr8_-_70745575 0.14 ENST00000524945.1
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr16_+_67195592 0.14 ENST00000519378.1
FBXL8
F-box and leucine-rich repeat protein 8
chr11_+_60197069 0.14 ENST00000528905.1
ENST00000528093.1
MS4A5
membrane-spanning 4-domains, subfamily A, member 5
chr13_+_48877895 0.13 ENST00000267163.4
RB1
retinoblastoma 1
chr12_-_117319236 0.13 ENST00000257572.5
HRK
harakiri, BCL2 interacting protein (contains only BH3 domain)
chr7_+_142636603 0.13 ENST00000409607.3
C7orf34
chromosome 7 open reading frame 34
chr16_+_84178850 0.12 ENST00000334315.5
DNAAF1
dynein, axonemal, assembly factor 1
chr11_+_65687158 0.11 ENST00000532933.1
DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr8_+_145065521 0.10 ENST00000534791.1
GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr11_+_236540 0.10 ENST00000532097.1
PSMD13
proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
chr7_+_142636440 0.10 ENST00000458732.1
C7orf34
chromosome 7 open reading frame 34
chr12_-_82752159 0.09 ENST00000552377.1
CCDC59
coiled-coil domain containing 59
chr14_+_72399833 0.09 ENST00000553530.1
ENST00000556437.1
RGS6
regulator of G-protein signaling 6
chr17_+_78388959 0.09 ENST00000518137.1
ENST00000520367.1
ENST00000523999.1
ENST00000323854.5
ENST00000522751.1
ENDOV
endonuclease V
chr18_+_77623668 0.08 ENST00000316249.3
KCNG2
potassium voltage-gated channel, subfamily G, member 2
chr11_-_65686496 0.07 ENST00000449692.3
C11orf68
chromosome 11 open reading frame 68
chr4_-_76598544 0.06 ENST00000515457.1
ENST00000357854.3
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chrX_+_72667090 0.05 ENST00000373514.2
CDX4
caudal type homeobox 4
chr17_+_4835580 0.05 ENST00000329125.5
GP1BA
glycoprotein Ib (platelet), alpha polypeptide
chr16_-_2581409 0.04 ENST00000567119.1
ENST00000565480.1
ENST00000382350.1
CEMP1
cementum protein 1
chr12_+_113495492 0.04 ENST00000257600.3
DTX1
deltex homolog 1 (Drosophila)
chr9_+_131445928 0.04 ENST00000372692.4
SET
SET nuclear oncogene
chr2_-_27357479 0.03 ENST00000406567.3
ENST00000260643.2
PREB
prolactin regulatory element binding
chr12_+_44152740 0.02 ENST00000440781.2
ENST00000431837.1
ENST00000550616.1
ENST00000448290.2
ENST00000551736.1
IRAK4
interleukin-1 receptor-associated kinase 4
chr1_+_155146318 0.02 ENST00000368385.4
ENST00000545012.1
ENST00000392451.2
ENST00000368383.3
ENST00000368382.1
ENST00000334634.4
TRIM46
tripartite motif containing 46
chr5_+_138940742 0.02 ENST00000398733.3
ENST00000253815.2
ENST00000505007.1
UBE2D2
ubiquitin-conjugating enzyme E2D 2
chr5_+_43120985 0.01 ENST00000515326.1
ZNF131
zinc finger protein 131
chr17_-_28661065 0.01 ENST00000328886.4
ENST00000538566.2
TMIGD1
transmembrane and immunoglobulin domain containing 1
chr17_-_47492236 0.00 ENST00000434917.2
ENST00000300408.3
ENST00000511832.1
ENST00000419140.2
PHB
prohibitin

Network of associatons between targets according to the STRING database.

First level regulatory network of TP73

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 GO:0071661 granzyme B production(GO:0071613) regulation of granzyme B production(GO:0071661) positive regulation of granzyme B production(GO:0071663)
0.4 1.6 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.4 3.5 GO:0001661 conditioned taste aversion(GO:0001661)
0.3 1.0 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.3 2.2 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)
0.3 2.0 GO:0006177 GMP biosynthetic process(GO:0006177)
0.3 2.2 GO:0070942 neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) neutrophil mediated killing of bacterium(GO:0070944)
0.2 5.4 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.2 1.0 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.2 1.6 GO:1904970 brush border assembly(GO:1904970)
0.2 0.7 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.2 1.8 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.2 0.6 GO:0042369 vitamin D catabolic process(GO:0042369)
0.1 0.6 GO:0071400 cellular response to oleic acid(GO:0071400)
0.1 0.5 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 0.4 GO:0071284 cellular response to lead ion(GO:0071284)
0.1 0.4 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.1 3.8 GO:0097421 liver regeneration(GO:0097421)
0.1 2.7 GO:0060065 uterus development(GO:0060065)
0.1 0.2 GO:0021589 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.1 1.0 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 1.2 GO:0051014 actin filament severing(GO:0051014)
0.1 0.5 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.7 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.1 GO:0034085 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922) negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.0 0.7 GO:0035878 nail development(GO:0035878)
0.0 1.4 GO:0071380 cellular response to prostaglandin E stimulus(GO:0071380)
0.0 0.4 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.3 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.7 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.3 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.2 GO:0090240 positive regulation of histone H4 acetylation(GO:0090240)
0.0 1.7 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.7 GO:2000615 regulation of histone H3-K9 acetylation(GO:2000615)
0.0 0.9 GO:0035067 negative regulation of histone acetylation(GO:0035067)
0.0 0.3 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.1 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.3 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 1.0 GO:0097435 fibril organization(GO:0097435)
0.0 0.4 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.5 GO:0045109 intermediate filament organization(GO:0045109)
0.0 1.5 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652)
0.0 0.5 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.8 GO:0042073 intraciliary transport(GO:0042073)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.5 GO:0035976 AP1 complex(GO:0035976)
0.2 1.0 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.2 0.5 GO:0033150 cytoskeletal calyx(GO:0033150)
0.1 0.7 GO:0044393 microspike(GO:0044393)
0.1 2.2 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.1 1.2 GO:0032059 bleb(GO:0032059)
0.0 1.8 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 1.3 GO:0042599 lamellar body(GO:0042599)
0.0 1.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 4.2 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.5 GO:0097512 cardiac myofibril(GO:0097512)
0.0 3.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.7 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.5 GO:0030056 hemidesmosome(GO:0030056)
0.0 2.0 GO:0005902 microvillus(GO:0005902)
0.0 0.5 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 1.5 GO:0005811 lipid particle(GO:0005811)
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.1 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.4 2.0 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.3 1.5 GO:0070051 fibrinogen binding(GO:0070051)
0.3 1.6 GO:0042015 interleukin-20 binding(GO:0042015)
0.2 1.7 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.2 2.2 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.2 1.4 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 0.9 GO:0016936 galactoside binding(GO:0016936)
0.1 0.6 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.1 0.6 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.1 0.3 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 1.0 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.4 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532) copper-dependent protein binding(GO:0032767)
0.1 1.8 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.2 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.1 0.7 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 0.7 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.1 1.4 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 2.5 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 1.2 GO:0005522 profilin binding(GO:0005522)
0.1 0.7 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.4 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 3.6 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.5 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.3 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 5.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.7 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.4 GO:0051525 NFAT protein binding(GO:0051525)
0.0 1.0 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.4 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 2.7 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.7 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 2.9 GO:0008201 heparin binding(GO:0008201)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.5 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 2.7 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 2.2 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 2.2 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 2.5 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.4 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.4 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.7 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 3.2 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.0 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 1.0 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.7 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.7 PID IL3 PATHWAY IL3-mediated signaling events
0.0 1.4 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.9 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 1.4 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 2.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 1.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 2.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.5 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.7 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 3.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.7 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.6 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.9 REACTOME MYOGENESIS Genes involved in Myogenesis