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Illumina Body Map 2: averaged replicates

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Results for UBP1

Z-value: 1.38

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Transcription factors associated with UBP1

Gene Symbol Gene ID Gene Info
UBP1
ENSG00000153560.7 upstream binding protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
UBP1hg19_v2_chr3_-_33481835_334819050.327.4e-02Click!

Activity profile of UBP1 motif

Sorted Z-values of UBP1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr21_+_43823983 4.25 ENST00000291535.6
ENST00000450356.1
ENST00000319294.6
ENST00000398367.1
UBASH3A
ubiquitin associated and SH3 domain containing A
chr7_+_142498725 3.92 ENST00000466254.1
TRBC2
T cell receptor beta constant 2
chr22_+_22385332 3.91 ENST00000390282.2
IGLV4-69
immunoglobulin lambda variable 4-69
chr2_-_89442621 3.83 ENST00000492167.1
IGKV3-20
immunoglobulin kappa variable 3-20
chr22_+_22676808 3.32 ENST00000390290.2
IGLV1-51
immunoglobulin lambda variable 1-51
chr22_+_22730353 3.31 ENST00000390296.2
IGLV5-45
immunoglobulin lambda variable 5-45
chr6_+_32709119 3.07 ENST00000374940.3
HLA-DQA2
major histocompatibility complex, class II, DQ alpha 2
chr19_-_51875523 3.06 ENST00000593572.1
ENST00000595157.1
NKG7
natural killer cell group 7 sequence
chr7_+_142829162 2.95 ENST00000291009.3
PIP
prolactin-induced protein
chrX_+_78426469 2.66 ENST00000276077.1
GPR174
G protein-coupled receptor 174
chr22_+_22707260 2.23 ENST00000390293.1
IGLV5-48
immunoglobulin lambda variable 5-48 (non-functional)
chr6_+_6588316 2.16 ENST00000379953.2
LY86
lymphocyte antigen 86
chrX_+_13587712 1.91 ENST00000361306.1
ENST00000380602.3
EGFL6
EGF-like-domain, multiple 6
chr15_+_81475047 1.88 ENST00000559388.1
IL16
interleukin 16
chr19_-_39104556 1.83 ENST00000423454.2
MAP4K1
mitogen-activated protein kinase kinase kinase kinase 1
chr3_+_111260980 1.76 ENST00000438817.2
CD96
CD96 molecule
chr12_+_47473369 1.71 ENST00000546455.1
PCED1B
PC-esterase domain containing 1B
chr17_+_32683456 1.59 ENST00000225844.2
CCL13
chemokine (C-C motif) ligand 13
chr6_+_31555045 1.57 ENST00000396101.3
ENST00000490742.1
LST1
leukocyte specific transcript 1
chr19_-_54784937 1.55 ENST00000434421.1
ENST00000314446.5
ENST00000391749.4
LILRB2
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
chr3_+_111260856 1.53 ENST00000352690.4
CD96
CD96 molecule
chr3_+_111260954 1.51 ENST00000283285.5
CD96
CD96 molecule
chr14_+_75988768 1.46 ENST00000286639.6
BATF
basic leucine zipper transcription factor, ATF-like
chr1_-_202129704 1.28 ENST00000476061.1
ENST00000544762.1
ENST00000467283.1
ENST00000464870.1
ENST00000435759.2
ENST00000486116.1
ENST00000543735.1
ENST00000308986.5
ENST00000477625.1
PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr1_-_202129105 1.10 ENST00000367279.4
PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr19_+_917287 1.04 ENST00000592648.1
ENST00000234371.5
KISS1R
KISS1 receptor
chr17_+_74381343 1.04 ENST00000392496.3
SPHK1
sphingosine kinase 1
chr22_+_38071615 1.03 ENST00000215909.5
LGALS1
lectin, galactoside-binding, soluble, 1
chr2_+_228678550 0.95 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr1_+_48688357 0.94 ENST00000533824.1
ENST00000438567.2
ENST00000236495.5
ENST00000420136.2
SLC5A9
solute carrier family 5 (sodium/sugar cotransporter), member 9
chr12_-_8815215 0.83 ENST00000544889.1
ENST00000543369.1
MFAP5
microfibrillar associated protein 5
chr12_-_8815299 0.83 ENST00000535336.1
MFAP5
microfibrillar associated protein 5
chr15_+_96904487 0.79 ENST00000600790.1
AC087477.1
Uncharacterized protein
chr9_+_112852477 0.78 ENST00000480388.1
AKAP2
A kinase (PRKA) anchor protein 2
chrY_+_2803322 0.76 ENST00000383052.1
ENST00000155093.3
ENST00000449237.1
ENST00000443793.1
ZFY
zinc finger protein, Y-linked
chr11_+_7506837 0.75 ENST00000528758.1
OLFML1
olfactomedin-like 1
chr1_-_168698433 0.73 ENST00000367817.3
DPT
dermatopontin
chr9_-_35685452 0.73 ENST00000607559.1
TPM2
tropomyosin 2 (beta)
chr12_-_47473425 0.72 ENST00000550413.1
AMIGO2
adhesion molecule with Ig-like domain 2
chr1_+_221054411 0.67 ENST00000427693.1
HLX
H2.0-like homeobox
chr11_-_102668879 0.66 ENST00000315274.6
MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chrX_+_115567767 0.65 ENST00000371900.4
SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr17_-_5138099 0.63 ENST00000571800.1
ENST00000574081.1
ENST00000399600.4
ENST00000574297.1
SCIMP
SLP adaptor and CSK interacting membrane protein
chr15_-_42343388 0.58 ENST00000399518.3
PLA2G4E
phospholipase A2, group IVE
chr11_+_10326612 0.57 ENST00000534464.1
ENST00000530439.1
ENST00000524948.1
ENST00000528655.1
ENST00000526492.1
ENST00000525063.1
ADM
adrenomedullin
chr15_-_77712477 0.56 ENST00000560626.2
PEAK1
pseudopodium-enriched atypical kinase 1
chr12_+_6898674 0.56 ENST00000541982.1
ENST00000539492.1
CD4
CD4 molecule
chr9_-_130497565 0.54 ENST00000336067.6
ENST00000373281.5
ENST00000373284.5
ENST00000458505.3
TOR2A
torsin family 2, member A
chr11_+_10326918 0.51 ENST00000528544.1
ADM
adrenomedullin
chr11_+_7506713 0.50 ENST00000329293.3
ENST00000534244.1
OLFML1
olfactomedin-like 1
chr19_-_51538148 0.50 ENST00000319590.4
ENST00000250351.4
KLK12
kallikrein-related peptidase 12
chr4_-_57524061 0.48 ENST00000508121.1
HOPX
HOP homeobox
chr4_+_156587979 0.48 ENST00000511507.1
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr5_-_41510656 0.47 ENST00000377801.3
PLCXD3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chrX_-_65253506 0.46 ENST00000427538.1
VSIG4
V-set and immunoglobulin domain containing 4
chr4_-_159080806 0.45 ENST00000590648.1
FAM198B
family with sequence similarity 198, member B
chr4_+_156587853 0.44 ENST00000506455.1
ENST00000511108.1
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr1_+_47901689 0.44 ENST00000334793.5
FOXD2
forkhead box D2
chr14_-_75330537 0.43 ENST00000556084.2
ENST00000556489.2
ENST00000445876.1
PROX2
prospero homeobox 2
chr4_+_156588115 0.42 ENST00000455639.2
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr16_-_67970990 0.42 ENST00000358514.4
PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
chr13_+_24844979 0.40 ENST00000454083.1
SPATA13
spermatogenesis associated 13
chr7_+_150706010 0.39 ENST00000475017.1
NOS3
nitric oxide synthase 3 (endothelial cell)
chr13_+_24844857 0.35 ENST00000409126.1
ENST00000343003.6
SPATA13
spermatogenesis associated 13
chr12_-_123717711 0.35 ENST00000537854.1
MPHOSPH9
M-phase phosphoprotein 9
chr5_-_111093717 0.34 ENST00000507032.2
NREP
neuronal regeneration related protein
chr3_-_100712352 0.33 ENST00000471714.1
ENST00000284322.5
ABI3BP
ABI family, member 3 (NESH) binding protein
chr1_+_155108294 0.32 ENST00000303343.8
ENST00000368404.4
ENST00000368401.5
SLC50A1
solute carrier family 50 (sugar efflux transporter), member 1
chr5_-_111093759 0.30 ENST00000509979.1
ENST00000513100.1
ENST00000508161.1
ENST00000455559.2
NREP
neuronal regeneration related protein
chr17_-_42327236 0.30 ENST00000399246.2
AC003102.1
AC003102.1
chr17_-_62493131 0.29 ENST00000539111.2
POLG2
polymerase (DNA directed), gamma 2, accessory subunit
chr19_+_41257084 0.29 ENST00000601393.1
SNRPA
small nuclear ribonucleoprotein polypeptide A
chr1_-_158687905 0.29 ENST00000368145.1
ENST00000368146.1
OR6K3
olfactory receptor, family 6, subfamily K, member 3
chr4_+_55096489 0.28 ENST00000504461.1
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr17_-_27188984 0.27 ENST00000582320.2
MIR144
microRNA 451b
chr4_-_76861392 0.26 ENST00000505594.1
NAAA
N-acylethanolamine acid amidase
chr13_+_24844819 0.24 ENST00000399949.2
SPATA13
spermatogenesis associated 13
chr19_-_58459039 0.24 ENST00000282308.3
ENST00000598928.1
ZNF256
zinc finger protein 256
chr3_+_29323043 0.22 ENST00000452462.1
ENST00000456853.1
RBMS3
RNA binding motif, single stranded interacting protein 3
chr15_+_41136734 0.22 ENST00000568580.1
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr11_-_65314905 0.21 ENST00000527339.1
LTBP3
latent transforming growth factor beta binding protein 3
chr12_+_123717967 0.20 ENST00000536130.1
ENST00000546132.1
C12orf65
chromosome 12 open reading frame 65
chr19_-_49864746 0.20 ENST00000598810.1
TEAD2
TEA domain family member 2
chr8_-_107782463 0.20 ENST00000311955.3
ABRA
actin-binding Rho activating protein
chr15_-_77712429 0.19 ENST00000564328.1
ENST00000558305.1
PEAK1
pseudopodium-enriched atypical kinase 1
chr10_-_75676400 0.19 ENST00000412307.2
C10orf55
chromosome 10 open reading frame 55
chr8_-_28747717 0.19 ENST00000416984.2
INTS9
integrator complex subunit 9
chr5_-_93447333 0.18 ENST00000395965.3
ENST00000505869.1
ENST00000509163.1
FAM172A
family with sequence similarity 172, member A
chr2_+_162087577 0.18 ENST00000439442.1
TANK
TRAF family member-associated NFKB activator
chr8_-_28747424 0.18 ENST00000523436.1
ENST00000397363.4
ENST00000521777.1
ENST00000520184.1
ENST00000521022.1
INTS9
integrator complex subunit 9
chr11_+_128761220 0.18 ENST00000529694.1
KCNJ5
potassium inwardly-rectifying channel, subfamily J, member 5
chr6_-_4347271 0.16 ENST00000437430.2
RP3-527G5.1
RP3-527G5.1
chr2_+_113033164 0.15 ENST00000409871.1
ENST00000343936.4
ZC3H6
zinc finger CCCH-type containing 6
chr13_-_23949671 0.15 ENST00000402364.1
SACS
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr4_+_42895284 0.14 ENST00000399770.2
GRXCR1
glutaredoxin, cysteine rich 1
chr7_-_33842742 0.13 ENST00000420185.1
ENST00000440034.1
RP11-89N17.4
RP11-89N17.4
chr8_+_28747884 0.10 ENST00000287701.10
ENST00000444075.1
ENST00000403668.2
ENST00000519662.1
ENST00000558662.1
ENST00000523613.1
ENST00000560599.1
ENST00000397358.3
HMBOX1
homeobox containing 1
chr7_+_132937820 0.09 ENST00000393161.2
ENST00000253861.4
EXOC4
exocyst complex component 4
chr1_-_150669604 0.09 ENST00000427665.1
ENST00000540514.1
GOLPH3L
golgi phosphoprotein 3-like
chr5_+_34656331 0.09 ENST00000265109.3
RAI14
retinoic acid induced 14
chr5_+_95998070 0.08 ENST00000421689.2
ENST00000510756.1
ENST00000512620.1
CAST
calpastatin
chr14_-_92413353 0.08 ENST00000556154.1
FBLN5
fibulin 5
chr16_+_29823427 0.08 ENST00000358758.7
ENST00000567659.1
ENST00000572820.1
PRRT2
proline-rich transmembrane protein 2
chr17_+_48450575 0.07 ENST00000338165.4
ENST00000393271.2
ENST00000511519.2
EME1
essential meiotic structure-specific endonuclease 1
chr11_-_84028339 0.06 ENST00000398301.2
DLG2
discs, large homolog 2 (Drosophila)
chr1_-_114302086 0.05 ENST00000369604.1
ENST00000357783.2
PHTF1
putative homeodomain transcription factor 1
chr12_+_123717458 0.02 ENST00000253233.1
C12orf65
chromosome 12 open reading frame 65
chr14_-_92413727 0.02 ENST00000267620.10
FBLN5
fibulin 5
chrX_+_149887090 0.01 ENST00000538506.1
MTMR1
myotubularin related protein 1
chr11_+_124824000 0.01 ENST00000529051.1
ENST00000344762.5
CCDC15
coiled-coil domain containing 15
chr6_+_142623758 0.01 ENST00000541199.1
ENST00000435011.2
GPR126
G protein-coupled receptor 126

Network of associatons between targets according to the STRING database.

First level regulatory network of UBP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.8 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.5 1.6 GO:0090265 positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265)
0.3 1.0 GO:0046521 sphingoid catabolic process(GO:0046521)
0.3 0.9 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.2 1.3 GO:0052551 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.2 2.2 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.2 1.6 GO:0002774 Fc receptor mediated inhibitory signaling pathway(GO:0002774)
0.2 1.0 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 0.6 GO:0035397 helper T cell enhancement of adaptive immune response(GO:0035397)
0.1 4.3 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 1.1 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 0.3 GO:1901656 glycoside transport(GO:1901656)
0.1 3.8 GO:0003094 glomerular filtration(GO:0003094)
0.1 2.9 GO:0070233 negative regulation of T cell apoptotic process(GO:0070233)
0.1 1.9 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.1 0.4 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.1 0.7 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.4 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.1 1.5 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.1 0.2 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 2.7 GO:0043029 T cell homeostasis(GO:0043029)
0.1 1.8 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 3.9 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 9.4 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.3 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
0.0 0.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.3 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.2 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.0 1.7 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 3.3 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 3.1 GO:0031295 T cell costimulation(GO:0031295)
0.0 0.2 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.5 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.9 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.6 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.7 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 1.6 GO:0050672 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.0 0.5 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.2 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 0.1 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0 2.4 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.4 GO:0016180 snRNA processing(GO:0016180)
0.0 0.7 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.2 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 1.0 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:0048251 elastic fiber assembly(GO:0048251)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0071751 IgA immunoglobulin complex(GO:0071745) IgA immunoglobulin complex, circulating(GO:0071746) monomeric IgA immunoglobulin complex(GO:0071748) polymeric IgA immunoglobulin complex(GO:0071749) secretory IgA immunoglobulin complex(GO:0071751)
0.5 1.6 GO:0044299 C-fiber(GO:0044299)
0.1 3.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.3 GO:0000229 cytoplasmic chromosome(GO:0000229)
0.1 3.9 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 1.7 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.4 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.2 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 1.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.7 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.4 GO:0032039 integrator complex(GO:0032039)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.6 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.1 GO:0071953 elastic fiber(GO:0071953)
0.0 1.9 GO:0005604 basement membrane(GO:0005604)
0.0 1.3 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0030395 lactose binding(GO:0030395)
0.3 1.6 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.3 0.9 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.2 1.6 GO:0032396 inhibitory MHC class I receptor activity(GO:0032396)
0.2 3.1 GO:0032395 MHC class II receptor activity(GO:0032395)
0.2 2.9 GO:0019864 IgG binding(GO:0019864)
0.1 1.0 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 2.7 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.1 0.6 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.9 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 18.3 GO:0003823 antigen binding(GO:0003823)
0.1 1.8 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.3 GO:0005018 platelet-derived growth factor alpha-receptor activity(GO:0005018)
0.1 1.9 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 0.4 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.3 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 1.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.6 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.2 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.2 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 1.0 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.7 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 1.0 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 1.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 2.4 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 1.8 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.0 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 1.8 ST ADRENERGIC Adrenergic Pathway
0.0 0.6 PID ARF 3PATHWAY Arf1 pathway
0.0 1.0 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.7 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.6 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 6.4 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.7 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.3 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 1.0 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction