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Illumina Body Map 2: averaged replicates
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Results for UCACAGU
Z-value: 1.77
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miRNA associated with seed UCACAGU
Network of associatons between targets according to the STRING database.
First level regulatory network of UCACAGU
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 4.2 | GO:0060707 | trophoblast giant cell differentiation(GO:0060707) |
| 1.3 | 3.9 | GO:0060435 | bronchiole development(GO:0060435) |
| 0.5 | 3.2 | GO:1903588 | negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588) |
| 0.1 | 2.9 | GO:0060856 | establishment of blood-brain barrier(GO:0060856) |
| 0.6 | 2.8 | GO:2000969 | positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969) |
| 0.3 | 2.7 | GO:1900019 | regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020) |
| 0.2 | 2.4 | GO:0006657 | CDP-choline pathway(GO:0006657) |
| 0.1 | 2.4 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
| 0.1 | 2.4 | GO:0032486 | Rap protein signal transduction(GO:0032486) |
| 0.3 | 2.3 | GO:0003344 | pericardium morphogenesis(GO:0003344) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 8.9 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.0 | 4.4 | GO:0043296 | apical junction complex(GO:0043296) |
| 0.0 | 3.5 | GO:0030175 | filopodium(GO:0030175) |
| 0.1 | 2.8 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.0 | 2.4 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.0 | 2.1 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.0 | 2.1 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.7 | 2.0 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.0 | 1.9 | GO:0030315 | T-tubule(GO:0030315) |
| 0.0 | 1.8 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 12.4 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
| 0.1 | 4.2 | GO:0005112 | Notch binding(GO:0005112) |
| 0.0 | 3.8 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.1 | 3.5 | GO:0030169 | low-density lipoprotein particle binding(GO:0030169) |
| 0.1 | 3.4 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 0.3 | 2.9 | GO:0043237 | laminin-1 binding(GO:0043237) |
| 0.1 | 2.4 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
| 0.1 | 2.3 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 0.1 | 2.2 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.0 | 2.2 | GO:0042056 | chemoattractant activity(GO:0042056) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 6.9 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.0 | 4.2 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 4.1 | PID SYNDECAN 1 PATHWAY | Syndecan-1-mediated signaling events |
| 0.1 | 3.9 | SA B CELL RECEPTOR COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
| 0.1 | 3.6 | PID INTEGRIN CS PATHWAY | Integrin family cell surface interactions |
| 0.1 | 3.1 | PID PDGFRA PATHWAY | PDGFR-alpha signaling pathway |
| 0.0 | 2.5 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.1 | 2.3 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.0 | 2.3 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.0 | 1.8 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.6 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.1 | 3.3 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.1 | 3.2 | REACTOME REGULATION OF BETA CELL DEVELOPMENT | Genes involved in Regulation of beta-cell development |
| 0.0 | 3.1 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.0 | 3.0 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.1 | 2.7 | REACTOME HYALURONAN METABOLISM | Genes involved in Hyaluronan metabolism |
| 0.1 | 2.7 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.0 | 2.7 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.1 | 2.5 | REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Norepinephrine Neurotransmitter Release Cycle |
| 0.0 | 2.3 | REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE | Genes involved in Cell death signalling via NRAGE, NRIF and NADE |