Motif ID: UCCAGUU

Z-value: 1.908


Mature miRNA associated with seed UCCAGUU:

NamemiRBase Accession
hsa-miR-145-5p MIMAT0000437
hsa-miR-5195-3p MIMAT0021127



Activity profile for motif UCCAGUU.

activity profile for motif UCCAGUU


Sorted Z-values histogram for motif UCCAGUU

Sorted Z-values for motif UCCAGUU



Network of associatons between targets according to the STRING database.



First level regulatory network of UCCAGUU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr21_-_28338732 3.230 ENST00000284987.5
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr7_+_114562172 2.381 ENST00000393486.1
ENST00000257724.3
MDFIC

MyoD family inhibitor domain containing

chr3_+_30648066 2.326 ENST00000359013.4
TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr11_+_128563652 2.279 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr11_-_86666427 2.141 ENST00000531380.1
FZD4
frizzled family receptor 4
chr1_-_21671968 2.134 ENST00000415912.2
ECE1
endothelin converting enzyme 1
chr1_-_119532127 2.121 ENST00000207157.3
TBX15
T-box 15
chr2_+_121103706 1.903 ENST00000295228.3
INHBB
inhibin, beta B
chr11_+_111473108 1.863 ENST00000304987.3
SIK2
salt-inducible kinase 2
chr11_+_76494253 1.856 ENST00000333090.4
TSKU
tsukushi, small leucine rich proteoglycan
chr10_-_60027642 1.763 ENST00000373935.3
IPMK
inositol polyphosphate multikinase
chr5_-_39425068 1.589 ENST00000515700.1
ENST00000339788.6
DAB2

Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)

chr12_-_92539614 1.581 ENST00000256015.3
BTG1
B-cell translocation gene 1, anti-proliferative
chr15_+_52121822 1.577 ENST00000558455.1
ENST00000308580.7
TMOD3

tropomodulin 3 (ubiquitous)

chr9_-_110251836 1.542 ENST00000374672.4
KLF4
Kruppel-like factor 4 (gut)
chr8_-_6420930 1.495 ENST00000325203.5
ANGPT2
angiopoietin 2
chr1_-_147245484 1.470 ENST00000271348.2
GJA5
gap junction protein, alpha 5, 40kDa
chr18_+_3247413 1.470 ENST00000579226.1
ENST00000217652.3
MYL12A

myosin, light chain 12A, regulatory, non-sarcomeric

chr12_-_125348448 1.435 ENST00000339570.5
SCARB1
scavenger receptor class B, member 1
chr2_-_227664474 1.425 ENST00000305123.5
IRS1
insulin receptor substrate 1
chr8_-_23712312 1.400 ENST00000290271.2
STC1
stanniocalcin 1
chr1_-_159893507 1.388 ENST00000368096.1
TAGLN2
transgelin 2
chr12_+_53774423 1.372 ENST00000426431.2
SP1
Sp1 transcription factor
chr6_+_143929307 1.370 ENST00000427704.2
ENST00000305766.6
PHACTR2

phosphatase and actin regulator 2

chr7_+_130126012 1.370 ENST00000341441.5
MEST
mesoderm specific transcript
chr1_+_101702417 1.322 ENST00000305352.6
S1PR1
sphingosine-1-phosphate receptor 1
chr7_-_27183263 1.300 ENST00000222726.3
HOXA5
homeobox A5
chr17_+_74261277 1.294 ENST00000327490.6
UBALD2
UBA-like domain containing 2
chr10_-_131762105 1.288 ENST00000368648.3
ENST00000355311.5
EBF3

early B-cell factor 3

chr5_-_158526756 1.263 ENST00000313708.6
ENST00000517373.1
EBF1

early B-cell factor 1

chr21_+_40177143 1.261 ENST00000360214.3
ETS2
v-ets avian erythroblastosis virus E26 oncogene homolog 2
chr17_-_62207485 1.253 ENST00000433197.3
ERN1
endoplasmic reticulum to nucleus signaling 1
chr15_+_41523335 1.245 ENST00000334660.5
CHP1
calcineurin-like EF-hand protein 1
chr11_-_128392085 1.240 ENST00000526145.2
ENST00000531611.1
ENST00000319397.6
ENST00000345075.4
ENST00000535549.1
ETS1




v-ets avian erythroblastosis virus E26 oncogene homolog 1




chr17_-_38721711 1.232 ENST00000578085.1
ENST00000246657.2
CCR7

chemokine (C-C motif) receptor 7

chr4_+_160188889 1.232 ENST00000264431.4
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr1_+_206557366 1.225 ENST00000414007.1
ENST00000419187.2
SRGAP2

SLIT-ROBO Rho GTPase activating protein 2

chr22_-_46933067 1.211 ENST00000262738.3
ENST00000395964.1
CELSR1

cadherin, EGF LAG seven-pass G-type receptor 1

chr15_+_67358163 1.202 ENST00000327367.4
SMAD3
SMAD family member 3
chr14_+_50359773 1.178 ENST00000298316.5
ARF6
ADP-ribosylation factor 6
chr17_-_38020392 1.177 ENST00000346872.3
ENST00000439167.2
ENST00000377945.3
ENST00000394189.2
ENST00000377944.3
ENST00000377958.2
ENST00000535189.1
ENST00000377952.2
IKZF3







IKAROS family zinc finger 3 (Aiolos)







chr16_-_4987065 1.148 ENST00000590782.2
ENST00000345988.2
PPL

periplakin

chr3_-_156877997 1.135 ENST00000295926.3
CCNL1
cyclin L1
chr17_+_37026106 1.114 ENST00000318008.6
LASP1
LIM and SH3 protein 1
chr1_+_78956651 1.074 ENST00000370757.3
ENST00000370756.3
PTGFR

prostaglandin F receptor (FP)

chr13_-_41240717 1.064 ENST00000379561.5
FOXO1
forkhead box O1
chr1_-_38325256 1.060 ENST00000373036.4
MTF1
metal-regulatory transcription factor 1
chr1_+_76540386 1.055 ENST00000328299.3
ST6GALNAC3
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr10_+_112631547 1.053 ENST00000280154.7
ENST00000393104.2
PDCD4

programmed cell death 4 (neoplastic transformation inhibitor)

chr2_+_228336849 1.051 ENST00000409979.2
ENST00000310078.8
AGFG1

ArfGAP with FG repeats 1

chr3_+_111578027 1.031 ENST00000431670.2
ENST00000412622.1
PHLDB2

pleckstrin homology-like domain, family B, member 2

chr18_-_51751132 1.028 ENST00000256429.3
MBD2
methyl-CpG binding domain protein 2
chr2_+_36582857 1.014 ENST00000280527.2
CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr1_-_25291475 1.004 ENST00000338888.3
ENST00000399916.1
RUNX3

runt-related transcription factor 3

chr4_-_78740511 1.002 ENST00000504123.1
ENST00000264903.4
ENST00000515441.1
CNOT6L


CCR4-NOT transcription complex, subunit 6-like


chr15_-_41408409 1.000 ENST00000361937.3
INO80
INO80 complex subunit
chr10_-_118032697 0.987 ENST00000439649.3
GFRA1
GDNF family receptor alpha 1
chr2_+_204571198 0.986 ENST00000374481.3
ENST00000458610.2
ENST00000324106.8
CD28


CD28 molecule


chr7_+_100770328 0.980 ENST00000223095.4
ENST00000445463.2
SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr5_+_151151471 0.976 ENST00000394123.3
ENST00000543466.1
G3BP1

GTPase activating protein (SH3 domain) binding protein 1

chr5_-_44388899 0.972 ENST00000264664.4
FGF10
fibroblast growth factor 10
chr1_+_86046433 0.971 ENST00000451137.2
CYR61
cysteine-rich, angiogenic inducer, 61
chr19_+_16187085 0.967 ENST00000300933.4
TPM4
tropomyosin 4
chr6_+_106546808 0.961 ENST00000369089.3
PRDM1
PR domain containing 1, with ZNF domain
chr3_+_179370517 0.961 ENST00000263966.3
USP13
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr12_+_20522179 0.939 ENST00000359062.3
PDE3A
phosphodiesterase 3A, cGMP-inhibited
chr2_-_242212227 0.939 ENST00000427007.1
ENST00000458564.1
ENST00000452065.1
ENST00000427183.2
ENST00000426343.1
ENST00000422080.1
ENST00000449504.1
ENST00000449864.1
ENST00000391975.1
HDLBP








high density lipoprotein binding protein








chr10_+_72164135 0.934 ENST00000373218.4
EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
chr6_-_111804393 0.916 ENST00000368802.3
ENST00000368805.1
REV3L

REV3-like, polymerase (DNA directed), zeta, catalytic subunit

chrX_-_108976521 0.915 ENST00000469796.2
ENST00000502391.1
ENST00000508092.1
ENST00000340800.2
ENST00000348502.6
ACSL4




acyl-CoA synthetase long-chain family member 4




chr6_-_91006461 0.911 ENST00000257749.4
ENST00000343122.3
ENST00000406998.2
ENST00000453877.1
BACH2



BTB and CNC homology 1, basic leucine zipper transcription factor 2



chrX_+_73641286 0.907 ENST00000587091.1
SLC16A2
solute carrier family 16, member 2 (thyroid hormone transporter)
chr17_-_79479789 0.901 ENST00000571691.1
ENST00000571721.1
ENST00000573283.1
ENST00000575842.1
ENST00000575087.1
ENST00000570382.1
ENST00000331925.2
ACTG1






actin, gamma 1






chr16_+_69221028 0.900 ENST00000336278.4
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr7_+_116139424 0.878 ENST00000222693.4
CAV2
caveolin 2
chrX_-_20284958 0.869 ENST00000379565.3
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chrX_-_99891796 0.864 ENST00000373020.4
TSPAN6
tetraspanin 6
chr9_-_127952032 0.864 ENST00000456642.1
ENST00000373546.3
ENST00000373547.4
PPP6C


protein phosphatase 6, catalytic subunit


chr10_+_82213904 0.864 ENST00000429989.3
TSPAN14
tetraspanin 14
chr7_+_138916231 0.860 ENST00000473989.3
ENST00000288561.8
UBN2

ubinuclein 2

chr3_+_171758344 0.847 ENST00000336824.4
ENST00000423424.1
FNDC3B

fibronectin type III domain containing 3B

chr9_-_14314066 0.843 ENST00000397575.3
NFIB
nuclear factor I/B
chr12_-_120687948 0.841 ENST00000458477.2
PXN
paxillin
chr5_+_56111361 0.834 ENST00000399503.3
MAP3K1
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
chr11_+_32914579 0.833 ENST00000399302.2
QSER1
glutamine and serine rich 1
chr16_+_16043406 0.831 ENST00000399410.3
ENST00000399408.2
ENST00000346370.5
ENST00000351154.5
ENST00000345148.5
ENST00000349029.5
ABCC1





ATP-binding cassette, sub-family C (CFTR/MRP), member 1





chr3_-_112360116 0.825 ENST00000206423.3
ENST00000439685.2
CCDC80

coiled-coil domain containing 80

chr6_-_11232891 0.812 ENST00000379433.5
ENST00000379446.5
NEDD9

neural precursor cell expressed, developmentally down-regulated 9

chr20_+_52105495 0.808 ENST00000439873.2
AL354993.1
Cell growth-inhibiting protein 7; HCG1784586; Uncharacterized protein
chr2_+_203879568 0.806 ENST00000449802.1
NBEAL1
neurobeachin-like 1
chr1_-_185286461 0.799 ENST00000367498.3
IVNS1ABP
influenza virus NS1A binding protein
chr1_+_155099927 0.783 ENST00000368407.3
EFNA1
ephrin-A1
chr7_-_131241361 0.772 ENST00000378555.3
ENST00000322985.9
ENST00000541194.1
ENST00000537928.1
PODXL



podocalyxin-like



chr9_-_107690420 0.750 ENST00000423487.2
ENST00000374733.1
ENST00000374736.3
ABCA1


ATP-binding cassette, sub-family A (ABC1), member 1


chrX_+_48432892 0.747 ENST00000376759.3
ENST00000430348.2
RBM3

RNA binding motif (RNP1, RRM) protein 3

chr6_-_139695757 0.741 ENST00000367651.2
CITED2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr3_+_15643245 0.738 ENST00000303498.5
ENST00000437172.1
BTD

biotinidase

chr17_+_46125707 0.733 ENST00000584137.1
ENST00000362042.3
ENST00000585291.1
ENST00000357480.5
NFE2L1



nuclear factor, erythroid 2-like 1



chr8_-_13372395 0.732 ENST00000276297.4
ENST00000511869.1
DLC1

deleted in liver cancer 1

chr4_-_80994210 0.732 ENST00000403729.2
ANTXR2
anthrax toxin receptor 2
chr3_+_98451275 0.728 ENST00000265261.6
ENST00000497008.1
ST3GAL6

ST3 beta-galactoside alpha-2,3-sialyltransferase 6

chr5_-_178772424 0.728 ENST00000251582.7
ENST00000274609.5
ADAMTS2

ADAM metallopeptidase with thrombospondin type 1 motif, 2

chr6_+_80341000 0.726 ENST00000369838.4
SH3BGRL2
SH3 domain binding glutamic acid-rich protein like 2
chr7_-_5570229 0.723 ENST00000331789.5
ACTB
actin, beta
chr21_-_39870339 0.721 ENST00000429727.2
ENST00000398905.1
ENST00000398907.1
ENST00000453032.2
ENST00000288319.7
ERG




v-ets avian erythroblastosis virus E26 oncogene homolog




chr8_+_98656336 0.710 ENST00000336273.3
MTDH
metadherin
chr12_+_93771659 0.709 ENST00000337179.5
ENST00000415493.2
NUDT4

nudix (nucleoside diphosphate linked moiety X)-type motif 4

chr18_-_22932080 0.709 ENST00000584787.1
ENST00000361524.3
ENST00000538137.2
ZNF521


zinc finger protein 521


chr3_-_129325660 0.706 ENST00000324093.4
ENST00000393239.1
PLXND1

plexin D1

chr7_-_130418888 0.703 ENST00000310992.4
KLF14
Kruppel-like factor 14
chr5_-_157002775 0.699 ENST00000257527.4
ADAM19
ADAM metallopeptidase domain 19
chr19_-_16682987 0.698 ENST00000431408.1
ENST00000436553.2
ENST00000595753.1
SLC35E1


solute carrier family 35, member E1


chr16_+_19125252 0.693 ENST00000566735.1
ENST00000381440.3
ITPRIPL2

inositol 1,4,5-trisphosphate receptor interacting protein-like 2

chr7_+_5632436 0.688 ENST00000340250.6
ENST00000382361.3
FSCN1

fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)

chr11_-_119599794 0.686 ENST00000264025.3
PVRL1
poliovirus receptor-related 1 (herpesvirus entry mediator C)
chr4_+_25235597 0.683 ENST00000264864.6
PI4K2B
phosphatidylinositol 4-kinase type 2 beta
chr7_+_69064300 0.681 ENST00000342771.4
AUTS2
autism susceptibility candidate 2
chr1_-_208417620 0.681 ENST00000367033.3
PLXNA2
plexin A2
chr12_+_58087901 0.679 ENST00000315970.7
ENST00000547079.1
ENST00000439210.2
ENST00000389146.6
ENST00000413095.2
ENST00000551035.1
ENST00000257966.8
ENST00000435406.2
ENST00000550372.1
ENST00000389142.5
OS9









osteosarcoma amplified 9, endoplasmic reticulum lectin









chr3_-_183273477 0.675 ENST00000341319.3
KLHL6
kelch-like family member 6
chr11_-_10590238 0.675 ENST00000256178.3
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr19_-_47220335 0.662 ENST00000601806.1
ENST00000593363.1
ENST00000598633.1
ENST00000595515.1
ENST00000433867.1
PRKD2




protein kinase D2




chr1_+_15943995 0.657 ENST00000480945.1
DDI2
DNA-damage inducible 1 homolog 2 (S. cerevisiae)
chr9_+_112403088 0.654 ENST00000448454.2
PALM2
paralemmin 2
chr5_-_121413974 0.650 ENST00000231004.4
LOX
lysyl oxidase
chr1_+_10459111 0.650 ENST00000541529.1
ENST00000270776.8
ENST00000483936.1
ENST00000538557.1
PGD



phosphogluconate dehydrogenase



chr11_-_102323489 0.649 ENST00000361236.3
TMEM123
transmembrane protein 123
chr20_+_51588873 0.648 ENST00000371497.5
TSHZ2
teashirt zinc finger homeobox 2
chr1_-_94374946 0.636 ENST00000370238.3
GCLM
glutamate-cysteine ligase, modifier subunit
chr1_-_10856694 0.636 ENST00000377022.3
ENST00000344008.5
CASZ1

castor zinc finger 1

chr17_-_40306934 0.635 ENST00000550406.1
ENST00000547517.1
ENST00000393860.3
ENST00000346213.4
ENST00000592574.1
RAB5C



CTD-2132N18.3
RAB5C, member RAS oncogene family



Uncharacterized protein
chr1_-_205601064 0.633 ENST00000357992.4
ENST00000289703.4
ELK4

ELK4, ETS-domain protein (SRF accessory protein 1)

chr4_-_114682936 0.632 ENST00000454265.2
ENST00000429180.1
ENST00000418639.2
ENST00000394526.2
ENST00000296402.5
CAMK2D




calcium/calmodulin-dependent protein kinase II delta




chr5_+_78908233 0.631 ENST00000453514.1
ENST00000423041.2
ENST00000504233.1
ENST00000428308.2
PAPD4



PAP associated domain containing 4



chr8_-_119124045 0.625 ENST00000378204.2
EXT1
exostosin glycosyltransferase 1
chr1_-_67519782 0.625 ENST00000235345.5
SLC35D1
solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
chr7_-_139876812 0.624 ENST00000397560.2
JHDM1D
lysine (K)-specific demethylase 7A
chr7_+_77166592 0.616 ENST00000248594.6
PTPN12
protein tyrosine phosphatase, non-receptor type 12
chr11_-_118134997 0.612 ENST00000278937.2
MPZL2
myelin protein zero-like 2
chr17_-_27621125 0.610 ENST00000579665.1
ENST00000225388.4
NUFIP2

nuclear fragile X mental retardation protein interacting protein 2

chr16_-_79634595 0.609 ENST00000326043.4
ENST00000393350.1
MAF

v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog

chrX_-_11445856 0.608 ENST00000380736.1
ARHGAP6
Rho GTPase activating protein 6
chr21_+_45285050 0.605 ENST00000291572.8
AGPAT3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr10_+_5454505 0.605 ENST00000355029.4
NET1
neuroepithelial cell transforming 1
chr14_-_31676964 0.604 ENST00000553700.1
HECTD1
HECT domain containing E3 ubiquitin protein ligase 1
chr11_+_86748863 0.601 ENST00000340353.7
TMEM135
transmembrane protein 135
chr1_-_94703118 0.598 ENST00000260526.6
ENST00000370217.3
ARHGAP29

Rho GTPase activating protein 29

chr1_+_39456895 0.596 ENST00000432648.3
ENST00000446189.2
ENST00000372984.4
AKIRIN1


akirin 1


chr11_+_63706444 0.595 ENST00000377793.4
ENST00000456907.2
ENST00000539656.1
NAA40


N(alpha)-acetyltransferase 40, NatD catalytic subunit


chr1_+_167691191 0.593 ENST00000392121.3
ENST00000474859.1
MPZL1

myelin protein zero-like 1

chr5_+_14143728 0.589 ENST00000344204.4
ENST00000537187.1
TRIO

trio Rho guanine nucleotide exchange factor

chr12_+_53848505 0.584 ENST00000552819.1
ENST00000455667.3
PCBP2

poly(rC) binding protein 2

chr11_+_64794875 0.583 ENST00000377244.3
ENST00000534637.1
ENST00000524831.1
SNX15


sorting nexin 15


chr3_-_142166904 0.577 ENST00000264951.4
XRN1
5'-3' exoribonuclease 1
chr11_-_65381643 0.576 ENST00000309100.3
ENST00000529839.1
ENST00000526293.1
MAP3K11


mitogen-activated protein kinase kinase kinase 11


chr18_-_18691739 0.571 ENST00000399799.2
ROCK1
Rho-associated, coiled-coil containing protein kinase 1
chrX_+_70752917 0.569 ENST00000373719.3
OGT
O-linked N-acetylglucosamine (GlcNAc) transferase
chr5_+_135468516 0.566 ENST00000507118.1
ENST00000511116.1
ENST00000545279.1
ENST00000545620.1
SMAD5



SMAD family member 5



chr11_+_33278811 0.565 ENST00000303296.4
ENST00000379016.3
HIPK3

homeodomain interacting protein kinase 3

chr4_-_25864581 0.561 ENST00000399878.3
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr1_-_231473578 0.561 ENST00000360394.2
ENST00000366645.1
EXOC8

exocyst complex component 8

chr15_-_52970820 0.551 ENST00000261844.7
ENST00000399202.4
ENST00000562135.1
FAM214A


family with sequence similarity 214, member A


chr9_+_114659046 0.547 ENST00000374279.3
UGCG
UDP-glucose ceramide glucosyltransferase
chr3_-_113465065 0.545 ENST00000497255.1
ENST00000478020.1
ENST00000240922.3
ENST00000493900.1
NAA50



N(alpha)-acetyltransferase 50, NatE catalytic subunit



chr8_-_119964434 0.543 ENST00000297350.4
TNFRSF11B
tumor necrosis factor receptor superfamily, member 11b
chr6_+_7107999 0.542 ENST00000491191.1
ENST00000379938.2
ENST00000471433.1
RREB1


ras responsive element binding protein 1


chr9_+_19408999 0.537 ENST00000340967.2
ACER2
alkaline ceramidase 2
chr1_+_61547894 0.534 ENST00000403491.3
NFIA
nuclear factor I/A
chr13_-_72441315 0.532 ENST00000305425.4
ENST00000313174.7
ENST00000354591.4
DACH1


dachshund homolog 1 (Drosophila)


chr17_-_46682321 0.531 ENST00000225648.3
ENST00000484302.2
HOXB6

homeobox B6

chr12_+_111843749 0.525 ENST00000341259.2
SH2B3
SH2B adaptor protein 3
chr1_+_29063271 0.524 ENST00000373812.3
YTHDF2
YTH domain family, member 2
chr2_-_25475120 0.524 ENST00000380746.4
ENST00000402667.1
DNMT3A

DNA (cytosine-5-)-methyltransferase 3 alpha

chr8_-_66754172 0.523 ENST00000401827.3
PDE7A
phosphodiesterase 7A
chr7_-_92463210 0.521 ENST00000265734.4
CDK6
cyclin-dependent kinase 6
chr12_-_46766577 0.508 ENST00000256689.5
SLC38A2
solute carrier family 38, member 2
chr3_+_58291965 0.508 ENST00000445193.3
ENST00000295959.5
ENST00000466547.1
RPP14


ribonuclease P/MRP 14kDa subunit


chr13_-_29069232 0.505 ENST00000282397.4
ENST00000541932.1
ENST00000539099.1
FLT1


fms-related tyrosine kinase 1


chr19_-_4540486 0.505 ENST00000306390.6
LRG1
leucine-rich alpha-2-glycoprotein 1
chrX_+_154299753 0.504 ENST00000369459.2
ENST00000369462.1
ENST00000411985.1
ENST00000399042.1
BRCC3



BRCA1/BRCA2-containing complex, subunit 3



chr17_+_57970469 0.496 ENST00000443572.2
ENST00000406116.3
ENST00000225577.4
ENST00000393021.3
RPS6KB1



ribosomal protein S6 kinase, 70kDa, polypeptide 1



chr8_+_123793633 0.479 ENST00000314393.4
ZHX2
zinc fingers and homeoboxes 2
chr13_-_99630233 0.477 ENST00000376460.1
ENST00000442173.1
DOCK9

dedicator of cytokinesis 9

chr18_-_53255766 0.474 ENST00000566286.1
ENST00000564999.1
ENST00000566279.1
ENST00000354452.3
ENST00000356073.4
TCF4




transcription factor 4




chr6_+_147830063 0.471 ENST00000367474.1
SAMD5
sterile alpha motif domain containing 5
chr11_+_61447845 0.468 ENST00000257215.5
DAGLA
diacylglycerol lipase, alpha
chr10_+_60272814 0.464 ENST00000373886.3
BICC1
bicaudal C homolog 1 (Drosophila)
chr4_+_146402925 0.462 ENST00000302085.4
SMAD1
SMAD family member 1
chr11_+_9685604 0.452 ENST00000447399.2
ENST00000318950.6
SWAP70

SWAP switching B-cell complex 70kDa subunit

chr3_+_57994127 0.450 ENST00000490882.1
ENST00000295956.4
ENST00000358537.3
ENST00000429972.2
ENST00000348383.5
ENST00000357272.4
FLNB





filamin B, beta





chr12_-_96184533 0.436 ENST00000343702.4
ENST00000344911.4
NTN4

netrin 4

chr20_-_62462566 0.432 ENST00000245663.4
ENST00000302995.2
ZBTB46

zinc finger and BTB domain containing 46

chr17_+_7452336 0.431 ENST00000293826.4
TNFSF12-TNFSF13
TNFSF12-TNFSF13 readthrough
chr12_+_72233487 0.431 ENST00000482439.2
ENST00000550746.1
ENST00000491063.1
ENST00000319106.8
ENST00000485960.2
ENST00000393309.3
TBC1D15





TBC1 domain family, member 15





chr1_-_149982624 0.427 ENST00000417191.1
ENST00000369135.4
OTUD7B

OTU domain containing 7B

chr5_-_111754948 0.424 ENST00000261486.5
EPB41L4A
erythrocyte membrane protein band 4.1 like 4A
chr17_-_5389477 0.422 ENST00000572834.1
ENST00000570848.1
ENST00000571971.1
ENST00000158771.4
DERL2



derlin 2



chr17_+_38119216 0.420 ENST00000301659.4
GSDMA
gasdermin A
chr1_-_183604794 0.419 ENST00000367534.1
ENST00000359856.6
ENST00000294742.6
ARPC5


actin related protein 2/3 complex, subunit 5, 16kDa


chr16_+_67063036 0.418 ENST00000290858.6
ENST00000564034.1
CBFB

core-binding factor, beta subunit


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 1.9 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.8 2.3 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.8 2.3 GO:0060435 bronchiole development(GO:0060435)
0.7 2.1 GO:0061298 progesterone secretion(GO:0042701) retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.5 1.4 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.5 1.4 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.4 1.3 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.4 1.6 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.4 0.8 GO:0003176 aortic valve development(GO:0003176) aortic valve morphogenesis(GO:0003180)
0.4 1.5 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.4 2.1 GO:0034959 neuropeptide catabolic process(GO:0010813) substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.3 1.0 GO:0010757 chronological cell aging(GO:0001300) arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540) negative regulation of plasminogen activation(GO:0010757) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.3 1.6 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.2 1.2 GO:0030578 nuclear body organization(GO:0030575) PML body organization(GO:0030578)
0.2 0.4 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.2 0.4 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.2 3.5 GO:0032232 negative regulation of actin filament bundle assembly(GO:0032232)
0.2 1.5 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.2 0.6 GO:0032060 bleb assembly(GO:0032060)
0.2 0.8 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.2 0.9 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.2 0.9 GO:0070672 response to interleukin-15(GO:0070672)
0.2 0.5 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
0.2 0.5 GO:0014889 muscle atrophy(GO:0014889) response to leucine(GO:0043201) regulation of skeletal muscle tissue growth(GO:0048631)
0.2 0.9 GO:0019985 translesion synthesis(GO:0019985)
0.2 1.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.2 1.4 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.1 0.9 GO:0044854 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) positive regulation of dopamine receptor signaling pathway(GO:0060161) caveola assembly(GO:0070836) membrane assembly(GO:0071709)
0.1 0.7 GO:0010508 positive regulation of autophagy(GO:0010508)
0.1 0.6 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 0.8 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.1 1.0 GO:0045066 regulatory T cell differentiation(GO:0045066)
0.1 1.0 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.1 1.4 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.1 0.3 GO:0001999 renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999)
0.1 1.1 GO:0044413 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1 0.6 GO:0071557 histone H4-K20 demethylation(GO:0035574) histone H3-K27 demethylation(GO:0071557)
0.1 0.4 GO:0032235 obsolete negative regulation of calcium ion transport via store-operated calcium channel activity(GO:0032235)
0.1 1.2 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.1 0.6 GO:0071025 RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.1 0.6 GO:0019322 pentose biosynthetic process(GO:0019322)
0.1 0.4 GO:0060690 epithelial cell differentiation involved in salivary gland development(GO:0060690)
0.1 0.6 GO:0051409 response to nitrosative stress(GO:0051409)
0.1 0.3 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.1 2.5 GO:0001893 maternal placenta development(GO:0001893)
0.1 0.4 GO:0035624 receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.1 0.7 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.1 1.6 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 0.7 GO:0060037 pharyngeal system development(GO:0060037)
0.1 0.5 GO:0043045 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.1 0.5 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.1 0.6 GO:0051571 positive regulation of histone H3-K4 methylation(GO:0051571)
0.1 0.8 GO:0031053 primary miRNA processing(GO:0031053)
0.1 0.7 GO:0009249 protein lipoylation(GO:0009249)
0.1 0.7 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.6 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.1 0.4 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 0.5 GO:0042483 negative regulation of odontogenesis(GO:0042483) regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.1 0.6 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.7 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.1 2.7 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.1 0.9 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 0.5 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.1 0.3 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 0.4 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.1 0.5 GO:0007351 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.1 2.1 GO:0048701 embryonic cranial skeleton morphogenesis(GO:0048701)
0.1 0.4 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.1 0.3 GO:0001507 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.1 0.7 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.1 1.3 GO:0001569 patterning of blood vessels(GO:0001569)
0.1 1.1 GO:0007567 parturition(GO:0007567)
0.0 0.7 GO:0034405 response to fluid shear stress(GO:0034405)
0.0 0.2 GO:1902745 positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0 2.6 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.6 GO:0050687 negative regulation of defense response to virus(GO:0050687)
0.0 0.6 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.8 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.5 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 1.4 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 0.2 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.7 GO:0046718 viral entry into host cell(GO:0046718)
0.0 1.5 GO:0035050 embryonic heart tube development(GO:0035050)
0.0 0.3 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.7 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 1.1 GO:0046686 response to cadmium ion(GO:0046686)
0.0 1.9 GO:0046626 regulation of insulin receptor signaling pathway(GO:0046626) regulation of cellular response to insulin stimulus(GO:1900076)
0.0 0.3 GO:0032528 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0 0.8 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.0 0.1 GO:0007388 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.0 1.8 GO:0001841 neural tube formation(GO:0001841)
0.0 0.2 GO:0097576 vacuole fusion(GO:0097576)
0.0 0.1 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0 0.7 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 0.3 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.3 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.7 GO:0002467 germinal center formation(GO:0002467)
0.0 0.8 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.3 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 2.3 GO:0007498 mesoderm development(GO:0007498)
0.0 0.6 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.3 GO:1901984 negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0 0.1 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304) positive regulation of epithelial cell apoptotic process(GO:1904037) positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.1 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.5 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.4 GO:0095500 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 1.1 GO:0031424 keratinization(GO:0031424)
0.0 0.2 GO:0001953 negative regulation of cell-matrix adhesion(GO:0001953)
0.0 0.2 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.7 GO:0007032 endosome organization(GO:0007032)
0.0 0.6 GO:0009880 embryonic pattern specification(GO:0009880)
0.0 0.2 GO:0010042 response to manganese ion(GO:0010042)
0.0 0.7 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.1 GO:0000917 barrier septum assembly(GO:0000917) cell septum assembly(GO:0090529) mitotic cytokinetic process(GO:1902410)
0.0 0.9 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 1.2 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.6 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.1 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 1.5 GO:0051017 actin filament bundle assembly(GO:0051017) actin filament bundle organization(GO:0061572)
0.0 0.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 1.4 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275) actin-mediated cell contraction(GO:0070252)
0.0 0.5 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.8 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:0046984 regulation of hemoglobin biosynthetic process(GO:0046984)
0.0 1.3 GO:0034332 adherens junction organization(GO:0034332)
0.0 0.1 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.2 GO:0042987 amyloid precursor protein catabolic process(GO:0042987)
0.0 1.5 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.1 GO:0000098 sulfur amino acid catabolic process(GO:0000098) sulfur compound catabolic process(GO:0044273)
0.0 0.8 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.2 GO:0015695 organic cation transport(GO:0015695)
0.0 0.2 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.1 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.4 2.1 GO:0031310 intrinsic component of endosome membrane(GO:0031302) intrinsic component of vacuolar membrane(GO:0031310)
0.2 0.7 GO:0032584 growth cone membrane(GO:0032584)
0.2 1.4 GO:0005899 insulin receptor complex(GO:0005899)
0.2 0.9 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.2 0.6 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.1 0.5 GO:0000267 obsolete cell fraction(GO:0000267)
0.1 2.2 GO:0031528 microvillus membrane(GO:0031528)
0.1 0.7 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.1 0.5 GO:0070552 BRISC complex(GO:0070552)
0.1 0.7 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.7 GO:0071437 invadopodium(GO:0071437)
0.1 1.3 GO:0070688 MLL5-L complex(GO:0070688)
0.1 0.6 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.5 GO:0000791 euchromatin(GO:0000791)
0.1 1.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 0.4 GO:0002178 palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 0.3 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 0.4 GO:0001740 Barr body(GO:0001740)
0.1 0.4 GO:0032444 activin responsive factor complex(GO:0032444)
0.1 1.5 GO:0005922 connexon complex(GO:0005922)
0.1 0.7 GO:0005581 collagen trimer(GO:0005581)
0.0 3.5 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.8 GO:0030027 lamellipodium(GO:0030027)
0.0 0.6 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.4 GO:0005844 polysome(GO:0005844)
0.0 0.8 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.3 GO:0045298 tubulin complex(GO:0045298)
0.0 0.6 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 1.1 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.6 GO:0000145 exocyst(GO:0000145)
0.0 0.9 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.8 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.3 GO:0042598 obsolete vesicular fraction(GO:0042598)
0.0 0.9 GO:0005811 lipid particle(GO:0005811)
0.0 2.3 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.9 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 1.1 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.2 GO:1903561 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 1.6 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 0.7 GO:0043204 perikaryon(GO:0043204)
0.0 1.1 GO:0005884 actin filament(GO:0005884)
0.0 0.9 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.0 1.5 GO:0016459 myosin complex(GO:0016459)
0.0 0.2 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 3.0 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.3 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.1 GO:0030904 retromer complex(GO:0030904)
0.0 0.4 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 1.0 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.4 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.6 2.4 GO:0030957 Tat protein binding(GO:0030957)
0.6 2.3 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.5 2.2 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.4 1.8 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.4 0.7 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.3 0.9 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.3 0.9 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.3 1.4 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.2 0.7 GO:0047708 biotinidase activity(GO:0047708)
0.2 0.8 GO:0051435 BH4 domain binding(GO:0051435)
0.2 0.6 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.2 1.1 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.2 1.0 GO:0003696 satellite DNA binding(GO:0003696) methyl-CpG binding(GO:0008327)
0.2 0.5 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.2 1.0 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.2 0.6 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.2 1.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 1.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.9 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.6 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328) N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1 1.0 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1 1.2 GO:0031996 thioesterase binding(GO:0031996)
0.1 0.9 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 1.4 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1 2.7 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 0.6 GO:0071558 histone demethylase activity (H4-K20 specific)(GO:0035575) histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 2.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 1.5 GO:0005243 gap junction channel activity(GO:0005243)
0.1 1.3 GO:0046625 sphingolipid binding(GO:0046625)
0.1 0.7 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.7 GO:0050693 LBD domain binding(GO:0050693)
0.1 1.3 GO:0043274 phospholipase binding(GO:0043274)
0.1 0.7 GO:0046790 virion binding(GO:0046790)
0.1 0.2 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.1 0.4 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.7 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.6 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1 0.1 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.1 1.1 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.1 1.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 0.4 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.1 1.6 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 1.4 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 1.0 GO:0008242 omega peptidase activity(GO:0008242)
0.1 0.4 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.1 0.2 GO:0004370 glycerol kinase activity(GO:0004370)
0.1 0.6 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 0.3 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.5 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.6 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 1.8 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.1 0.5 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 0.2 GO:0004998 transferrin receptor activity(GO:0004998)
0.1 0.2 GO:0016362 activin receptor activity, type II(GO:0016362)
0.0 0.5 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.5 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.6 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 1.6 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.7 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.2 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.8 GO:0001968 fibronectin binding(GO:0001968)
0.0 7.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.2 GO:0008186 RNA-dependent ATPase activity(GO:0008186)
0.0 0.6 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.3 GO:0000403 Y-form DNA binding(GO:0000403)
0.0 2.0 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 2.0 GO:0002020 protease binding(GO:0002020)
0.0 1.8 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.5 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.3 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 1.0 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0 0.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.6 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.3 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.9 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.4 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.9 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.5 GO:0030332 cyclin binding(GO:0030332)
0.0 1.5 GO:1990782 receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0 0.8 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 2.9 GO:0005179 hormone activity(GO:0005179)
0.0 0.4 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.0 0.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0017002 activin receptor activity, type I(GO:0016361) activin-activated receptor activity(GO:0017002)
0.0 1.0 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.3 GO:0008143 poly(A) binding(GO:0008143) poly-purine tract binding(GO:0070717)
0.0 0.1 GO:0005224 ATP-binding and phosphorylation-dependent chloride channel activity(GO:0005224) channel-conductance-controlling ATPase activity(GO:0005260)
0.0 1.0 GO:0004527 exonuclease activity(GO:0004527)
0.0 0.2 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0 1.1 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.3 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.2 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.4 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 1.2 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.5 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.2 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.1 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 9.9 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 0.2 GO:0030276 clathrin binding(GO:0030276)
0.0 0.1 GO:0003701 obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0 0.1 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 1.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.2 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.7 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.3 SIG_IL4RECEPTOR_IN_B_LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.5 ST_INTERLEUKIN_4_PATHWAY Interleukin 4 (IL-4) Pathway
0.0 1.3 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.3 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 0.6 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.0 ST_JNK_MAPK_PATHWAY JNK MAPK Pathway
0.0 1.0 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction
0.0 0.3 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway