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Illumina Body Map 2: averaged replicates

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Results for VDR

Z-value: 1.52

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Transcription factors associated with VDR

Gene Symbol Gene ID Gene Info
VDR
ENSG00000111424.6 vitamin D receptor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
VDRhg19_v2_chr12_-_48276710_48276725-0.241.8e-01Click!

Activity profile of VDR motif

Sorted Z-values of VDR motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_108905325 3.07 ENST00000438339.1
ENST00000409880.1
ENST00000437390.2
SULT1C2
sulfotransferase family, cytosolic, 1C, member 2
chr21_-_47575481 2.99 ENST00000291670.5
ENST00000397748.1
ENST00000359679.2
ENST00000355384.2
ENST00000397746.3
ENST00000397743.1
FTCD
formimidoyltransferase cyclodeaminase
chr17_-_64225508 2.87 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr9_+_139839711 2.83 ENST00000224181.3
C8G
complement component 8, gamma polypeptide
chr7_-_95025661 2.73 ENST00000542556.1
ENST00000265627.5
ENST00000427422.1
ENST00000451904.1
PON1
PON3
paraoxonase 1
paraoxonase 3
chr17_-_6616678 2.71 ENST00000381074.4
ENST00000293800.6
ENST00000572352.1
ENST00000576323.1
ENST00000573648.1
SLC13A5
solute carrier family 13 (sodium-dependent citrate transporter), member 5
chr11_-_116663127 2.64 ENST00000433069.1
ENST00000542499.1
APOA5
apolipoprotein A-V
chrX_+_70435044 2.45 ENST00000374029.1
ENST00000374022.3
ENST00000447581.1
GJB1
gap junction protein, beta 1, 32kDa
chr17_-_7082861 2.42 ENST00000269299.3
ASGR1
asialoglycoprotein receptor 1
chr9_-_136603456 2.38 ENST00000427237.2
ENST00000439388.1
SARDH
sarcosine dehydrogenase
chr14_+_94640633 2.20 ENST00000304338.3
PPP4R4
protein phosphatase 4, regulatory subunit 4
chr14_+_95047744 2.11 ENST00000553511.1
ENST00000554633.1
ENST00000555681.1
ENST00000554276.1
SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr6_+_31916733 2.01 ENST00000483004.1
CFB
complement factor B
chr14_+_95048217 1.98 ENST00000557598.1
ENST00000556064.1
SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr5_-_147211226 1.94 ENST00000296695.5
SPINK1
serine peptidase inhibitor, Kazal type 1
chr20_+_42193856 1.94 ENST00000412111.1
ENST00000423407.3
SGK2
serum/glucocorticoid regulated kinase 2
chr7_+_155090271 1.93 ENST00000476756.1
INSIG1
insulin induced gene 1
chr20_-_61992738 1.87 ENST00000370263.4
CHRNA4
cholinergic receptor, nicotinic, alpha 4 (neuronal)
chr7_+_100318423 1.86 ENST00000252723.2
EPO
erythropoietin
chr2_+_108905095 1.84 ENST00000251481.6
ENST00000326853.5
SULT1C2
sulfotransferase family, cytosolic, 1C, member 2
chr7_+_155089486 1.74 ENST00000340368.4
ENST00000344756.4
ENST00000425172.1
ENST00000342407.5
INSIG1
insulin induced gene 1
chr3_+_190105909 1.68 ENST00000456423.1
CLDN16
claudin 16
chr9_+_139839686 1.63 ENST00000371634.2
C8G
complement component 8, gamma polypeptide
chr7_+_29234101 1.59 ENST00000435288.2
CHN2
chimerin 2
chr5_-_147211190 1.55 ENST00000510027.2
SPINK1
serine peptidase inhibitor, Kazal type 1
chr16_+_20685815 1.52 ENST00000561584.1
ACSM3
acyl-CoA synthetase medium-chain family member 3
chr12_-_96390108 1.52 ENST00000538703.1
ENST00000261208.3
HAL
histidine ammonia-lyase
chr7_+_29234028 1.50 ENST00000222792.6
CHN2
chimerin 2
chr2_-_89160425 1.50 ENST00000390239.2
IGKJ4
immunoglobulin kappa joining 4
chr19_-_3478477 1.49 ENST00000591708.1
C19orf77
chromosome 19 open reading frame 77
chr4_+_158142750 1.46 ENST00000505888.1
ENST00000449365.1
GRIA2
glutamate receptor, ionotropic, AMPA 2
chr6_-_25874440 1.40 ENST00000361703.6
ENST00000397060.4
SLC17A3
solute carrier family 17 (organic anion transporter), member 3
chr2_-_89161064 1.39 ENST00000390241.2
IGKJ2
immunoglobulin kappa joining 2
chr17_+_68100989 1.39 ENST00000585558.1
ENST00000392670.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr12_-_96390063 1.35 ENST00000541929.1
HAL
histidine ammonia-lyase
chr21_+_45905448 1.33 ENST00000449713.1
AP001065.15
AP001065.15
chr19_-_16045619 1.27 ENST00000402119.4
CYP4F11
cytochrome P450, family 4, subfamily F, polypeptide 11
chr19_-_16045665 1.24 ENST00000248041.8
CYP4F11
cytochrome P450, family 4, subfamily F, polypeptide 11
chr12_-_96389702 1.17 ENST00000552509.1
HAL
histidine ammonia-lyase
chr7_+_97840739 1.16 ENST00000609256.1
BHLHA15
basic helix-loop-helix family, member a15
chr4_+_85504075 1.15 ENST00000295887.5
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr3_-_27763803 1.13 ENST00000449599.1
EOMES
eomesodermin
chr22_+_35776354 1.04 ENST00000412893.1
HMOX1
heme oxygenase (decycling) 1
chr16_-_68404908 0.99 ENST00000574662.1
SMPD3
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
chr8_+_9183618 0.99 ENST00000518619.1
RP11-115J16.1
RP11-115J16.1
chr1_-_205325698 0.97 ENST00000460687.1
KLHDC8A
kelch domain containing 8A
chr20_+_36974759 0.97 ENST00000217407.2
LBP
lipopolysaccharide binding protein
chr13_+_24844819 0.97 ENST00000399949.2
SPATA13
spermatogenesis associated 13
chr1_-_205325850 0.93 ENST00000537168.1
KLHDC8A
kelch domain containing 8A
chr17_-_79805146 0.90 ENST00000415593.1
P4HB
prolyl 4-hydroxylase, beta polypeptide
chr1_-_75198940 0.89 ENST00000417775.1
CRYZ
crystallin, zeta (quinone reductase)
chr1_-_205325994 0.88 ENST00000491471.1
KLHDC8A
kelch domain containing 8A
chr3_-_27764190 0.88 ENST00000537516.1
EOMES
eomesodermin
chr13_+_24844857 0.88 ENST00000409126.1
ENST00000343003.6
SPATA13
spermatogenesis associated 13
chr1_-_205326161 0.87 ENST00000367156.3
ENST00000606887.1
ENST00000607173.1
KLHDC8A
kelch domain containing 8A
chr1_-_205326022 0.86 ENST00000367155.3
KLHDC8A
kelch domain containing 8A
chr2_-_89160770 0.82 ENST00000390240.2
IGKJ3
immunoglobulin kappa joining 3
chr5_+_175487692 0.80 ENST00000510151.1
FAM153B
family with sequence similarity 153, member B
chr19_+_18077881 0.80 ENST00000609922.1
KCNN1
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
chr12_+_79439461 0.80 ENST00000552624.1
SYT1
synaptotagmin I
chr7_+_1272522 0.78 ENST00000316333.8
UNCX
UNC homeobox
chr7_-_36764062 0.78 ENST00000435386.1
AOAH
acyloxyacyl hydrolase (neutrophil)
chr19_-_22715280 0.75 ENST00000593802.1
ZNF98
zinc finger protein 98
chr1_-_67519782 0.73 ENST00000235345.5
SLC35D1
solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
chr11_+_60869980 0.73 ENST00000544014.1
CD5
CD5 molecule
chr7_-_96132835 0.72 ENST00000356686.1
C7orf76
chromosome 7 open reading frame 76
chr14_+_21498360 0.71 ENST00000321760.6
ENST00000460647.2
ENST00000530140.2
ENST00000472458.1
TPPP2
tubulin polymerization-promoting protein family member 2
chr13_+_24844979 0.71 ENST00000454083.1
SPATA13
spermatogenesis associated 13
chr18_-_6414884 0.70 ENST00000317931.7
ENST00000284898.6
ENST00000400104.3
L3MBTL4
l(3)mbt-like 4 (Drosophila)
chr8_-_8046331 0.70 ENST00000594215.1
LRLE1
Liver-related low express protein 1; Uncharacterized protein
chr12_+_79439405 0.70 ENST00000552744.1
SYT1
synaptotagmin I
chr12_-_133050726 0.68 ENST00000595994.1
MUC8
mucin 8
chr10_-_18940501 0.66 ENST00000377304.4
NSUN6
NOP2/Sun domain family, member 6
chr4_-_36246060 0.65 ENST00000303965.4
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr7_-_36764004 0.65 ENST00000431169.1
AOAH
acyloxyacyl hydrolase (neutrophil)
chr5_-_7869108 0.64 ENST00000264669.5
ENST00000507572.1
ENST00000504695.1
FASTKD3
FAST kinase domains 3
chr2_+_220363579 0.63 ENST00000313597.5
ENST00000373917.3
ENST00000358215.3
ENST00000373908.1
ENST00000455657.1
ENST00000435316.1
ENST00000341142.3
GMPPA
GDP-mannose pyrophosphorylase A
chrX_-_73061339 0.62 ENST00000602863.1
XIST
X inactive specific transcript (non-protein coding)
chrX_+_153770421 0.62 ENST00000369609.5
ENST00000369607.1
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr7_-_36764142 0.61 ENST00000258749.5
ENST00000535891.1
AOAH
acyloxyacyl hydrolase (neutrophil)
chr18_-_48351743 0.61 ENST00000588444.1
ENST00000256425.2
ENST00000428869.2
MRO
maestro
chr3_+_46618727 0.61 ENST00000296145.5
TDGF1
teratocarcinoma-derived growth factor 1
chr17_+_53828333 0.60 ENST00000268896.5
PCTP
phosphatidylcholine transfer protein
chr7_+_65552756 0.60 ENST00000450043.1
AC068533.7
AC068533.7
chr5_-_39270725 0.60 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYB
FYN binding protein
chr11_-_111320706 0.59 ENST00000531398.1
POU2AF1
POU class 2 associating factor 1
chr14_-_101351184 0.59 ENST00000534062.1
RTL1
retrotransposon-like 1
chr11_-_7904464 0.57 ENST00000502624.2
ENST00000527565.1
RP11-35J10.5
RP11-35J10.5
chr11_-_61582579 0.57 ENST00000539419.1
ENST00000545245.1
ENST00000545405.1
ENST00000542506.1
FADS1
fatty acid desaturase 1
chr16_-_31105870 0.56 ENST00000394971.3
VKORC1
vitamin K epoxide reductase complex, subunit 1
chr4_-_36245561 0.56 ENST00000506189.1
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr5_-_63258261 0.55 ENST00000506598.1
HTR1A
5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
chr5_-_177210399 0.55 ENST00000510276.1
FAM153A
family with sequence similarity 153, member A
chr7_+_129015484 0.54 ENST00000490911.1
AHCYL2
adenosylhomocysteinase-like 2
chr1_+_198608292 0.54 ENST00000418674.1
PTPRC
protein tyrosine phosphatase, receptor type, C
chr2_+_11752379 0.53 ENST00000396123.1
GREB1
growth regulation by estrogen in breast cancer 1
chr20_+_48909240 0.53 ENST00000371639.3
RP11-290F20.1
RP11-290F20.1
chr12_-_25801478 0.53 ENST00000540106.1
ENST00000445693.1
ENST00000545543.1
ENST00000542224.1
IFLTD1
intermediate filament tail domain containing 1
chr11_-_15643937 0.53 ENST00000533082.1
RP11-531H8.2
RP11-531H8.2
chr8_-_73793975 0.53 ENST00000523881.1
RP11-1145L24.1
RP11-1145L24.1
chr11_+_113779704 0.53 ENST00000537778.1
HTR3B
5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
chr9_+_131644781 0.52 ENST00000259324.5
LRRC8A
leucine rich repeat containing 8 family, member A
chr16_-_31106048 0.51 ENST00000300851.6
VKORC1
vitamin K epoxide reductase complex, subunit 1
chr1_-_99470368 0.50 ENST00000263177.4
LPPR5
Lipid phosphate phosphatase-related protein type 5
chr10_-_134756030 0.50 ENST00000368586.5
ENST00000368582.2
TTC40
tetratricopeptide repeat domain 40
chr19_-_11494975 0.50 ENST00000222139.6
ENST00000592375.2
EPOR
erythropoietin receptor
chr16_-_2260834 0.49 ENST00000562360.1
ENST00000566018.1
BRICD5
BRICHOS domain containing 5
chr12_+_110011571 0.49 ENST00000539696.1
ENST00000228510.3
ENST00000392727.3
MVK
mevalonate kinase
chr16_-_31106211 0.49 ENST00000532364.1
ENST00000529564.1
ENST00000319788.7
ENST00000354895.4
ENST00000394975.2
RP11-196G11.1
VKORC1
Uncharacterized protein
vitamin K epoxide reductase complex, subunit 1
chr14_+_101359265 0.49 ENST00000599197.1
AL117190.3
Esophagus cancer-related gene-2 interaction susceptibility protein; Uncharacterized protein
chr6_+_131521120 0.49 ENST00000537868.1
AKAP7
A kinase (PRKA) anchor protein 7
chr4_-_39640700 0.49 ENST00000295958.5
SMIM14
small integral membrane protein 14
chr17_+_53828381 0.48 ENST00000576183.1
PCTP
phosphatidylcholine transfer protein
chr12_-_63328817 0.48 ENST00000228705.6
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chrX_+_149737046 0.47 ENST00000370396.2
ENST00000542741.1
ENST00000543350.1
ENST00000424519.1
ENST00000413012.2
MTM1
myotubularin 1
chr1_-_48227290 0.47 ENST00000594280.1
FLJ00388
FLJ00388
chr1_+_200993071 0.46 ENST00000446333.1
ENST00000458003.1
RP11-168O16.1
RP11-168O16.1
chr5_-_179227540 0.46 ENST00000520875.1
MGAT4B
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
chr2_+_38893208 0.46 ENST00000410063.1
GALM
galactose mutarotase (aldose 1-epimerase)
chr10_-_43892668 0.46 ENST00000544000.1
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr18_-_6414797 0.45 ENST00000583809.1
L3MBTL4
l(3)mbt-like 4 (Drosophila)
chr4_-_164534657 0.45 ENST00000339875.5
MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr5_+_177433406 0.45 ENST00000504530.1
FAM153C
family with sequence similarity 153, member C
chr14_+_22978168 0.45 ENST00000390505.1
TRAJ32
T cell receptor alpha joining 32
chr10_-_43892279 0.45 ENST00000443950.2
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr2_+_230787201 0.45 ENST00000283946.3
FBXO36
F-box protein 36
chr11_-_14992712 0.45 ENST00000486207.1
CALCA
calcitonin-related polypeptide alpha
chr16_-_30023615 0.45 ENST00000564979.1
ENST00000563378.1
DOC2A
double C2-like domains, alpha
chr20_+_3801162 0.44 ENST00000379573.2
ENST00000379567.2
ENST00000455742.1
ENST00000246041.2
AP5S1
adaptor-related protein complex 5, sigma 1 subunit
chr19_+_49122548 0.43 ENST00000245222.4
ENST00000340932.3
ENST00000601712.1
ENST00000600537.1
SPHK2
sphingosine kinase 2
chr1_-_200379180 0.43 ENST00000294740.3
ZNF281
zinc finger protein 281
chr4_-_103266626 0.43 ENST00000356736.4
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr1_-_221915418 0.43 ENST00000323825.3
ENST00000366899.3
DUSP10
dual specificity phosphatase 10
chrX_+_36254051 0.43 ENST00000378657.4
CXorf30
chromosome X open reading frame 30
chr12_+_52626898 0.43 ENST00000331817.5
KRT7
keratin 7
chr4_-_23735183 0.43 ENST00000507666.1
RP11-380P13.2
RP11-380P13.2
chr9_-_139343294 0.42 ENST00000313084.5
SEC16A
SEC16 homolog A (S. cerevisiae)
chr11_-_104817919 0.42 ENST00000533252.1
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr2_+_230787213 0.42 ENST00000409992.1
FBXO36
F-box protein 36
chr11_+_60869867 0.42 ENST00000347785.3
CD5
CD5 molecule
chr4_-_103266219 0.42 ENST00000394833.2
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr19_+_49122785 0.41 ENST00000598088.1
SPHK2
sphingosine kinase 2
chr2_+_38893047 0.40 ENST00000272252.5
GALM
galactose mutarotase (aldose 1-epimerase)
chr1_+_153750622 0.40 ENST00000532853.1
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chr7_+_2685164 0.40 ENST00000400376.2
TTYH3
tweety family member 3
chr19_-_54804173 0.40 ENST00000391744.3
ENST00000251390.3
LILRA3
leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3
chr8_+_119294456 0.40 ENST00000366457.2
AC023590.1
Uncharacterized protein
chr22_-_31536480 0.39 ENST00000215885.3
PLA2G3
phospholipase A2, group III
chr9_+_140125209 0.39 ENST00000538474.1
SLC34A3
solute carrier family 34 (type II sodium/phosphate contransporter), member 3
chr14_-_54908043 0.38 ENST00000556113.1
ENST00000553660.1
ENST00000395573.4
ENST00000557690.1
ENST00000216416.4
CNIH1
cornichon family AMPA receptor auxiliary protein 1
chr12_+_53895364 0.38 ENST00000552817.1
ENST00000394357.2
TARBP2
TAR (HIV-1) RNA binding protein 2
chr14_+_22591276 0.37 ENST00000390455.3
TRAV26-1
T cell receptor alpha variable 26-1
chr5_-_177209832 0.37 ENST00000393518.3
ENST00000505531.1
ENST00000503567.1
FAM153A
family with sequence similarity 153, member A
chr14_+_77244349 0.36 ENST00000554743.1
VASH1
vasohibin 1
chr19_+_16830815 0.36 ENST00000549814.1
NWD1
NACHT and WD repeat domain containing 1
chr2_-_32489922 0.36 ENST00000402280.1
NLRC4
NLR family, CARD domain containing 4
chr1_-_200992827 0.36 ENST00000332129.2
ENST00000422435.2
KIF21B
kinesin family member 21B
chr5_+_177433973 0.36 ENST00000507848.1
FAM153C
family with sequence similarity 153, member C
chr12_-_56848426 0.35 ENST00000257979.4
MIP
major intrinsic protein of lens fiber
chr3_-_122283079 0.35 ENST00000471785.1
ENST00000466126.1
PARP9
poly (ADP-ribose) polymerase family, member 9
chr1_-_99470558 0.35 ENST00000370188.3
LPPR5
Lipid phosphate phosphatase-related protein type 5
chr5_+_175488258 0.35 ENST00000512862.1
FAM153B
family with sequence similarity 153, member B
chr20_+_2276639 0.35 ENST00000381458.5
TGM3
transglutaminase 3
chr1_+_198608146 0.35 ENST00000367376.2
ENST00000352140.3
ENST00000594404.1
ENST00000598951.1
ENST00000530727.1
ENST00000442510.2
ENST00000367367.4
ENST00000348564.6
ENST00000367364.1
ENST00000413409.2
PTPRC
protein tyrosine phosphatase, receptor type, C
chr17_+_53828432 0.34 ENST00000573500.1
PCTP
phosphatidylcholine transfer protein
chr20_-_52790512 0.34 ENST00000216862.3
CYP24A1
cytochrome P450, family 24, subfamily A, polypeptide 1
chr3_+_184032919 0.33 ENST00000427845.1
ENST00000342981.4
ENST00000319274.6
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr14_-_75330537 0.33 ENST00000556084.2
ENST00000556489.2
ENST00000445876.1
PROX2
prospero homeobox 2
chr15_-_81282133 0.33 ENST00000261758.4
MESDC2
mesoderm development candidate 2
chr14_+_22984601 0.33 ENST00000390509.1
TRAJ28
T cell receptor alpha joining 28
chr14_+_100531615 0.32 ENST00000392920.3
EVL
Enah/Vasp-like
chr2_-_73511559 0.32 ENST00000521871.1
FBXO41
F-box protein 41
chr4_+_146601356 0.32 ENST00000438731.1
ENST00000511965.1
C4orf51
chromosome 4 open reading frame 51
chr16_+_69958887 0.32 ENST00000568684.1
WWP2
WW domain containing E3 ubiquitin protein ligase 2
chr22_-_29663954 0.32 ENST00000216085.7
RHBDD3
rhomboid domain containing 3
chr3_-_122283100 0.31 ENST00000492382.1
ENST00000462315.1
PARP9
poly (ADP-ribose) polymerase family, member 9
chr4_-_122302163 0.31 ENST00000394427.2
QRFPR
pyroglutamylated RFamide peptide receptor
chr14_+_58797974 0.31 ENST00000417477.2
ARID4A
AT rich interactive domain 4A (RBP1-like)
chr14_+_100531738 0.31 ENST00000555706.1
EVL
Enah/Vasp-like
chr17_-_36348610 0.31 ENST00000339023.4
ENST00000354664.4
TBC1D3
TBC1 domain family, member 3
chr11_+_57365150 0.30 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr10_-_106240032 0.29 ENST00000447860.1
RP11-127O4.3
RP11-127O4.3
chr6_+_56820018 0.29 ENST00000370746.3
BEND6
BEN domain containing 6
chr11_-_73882029 0.29 ENST00000539061.1
C2CD3
C2 calcium-dependent domain containing 3
chr5_+_7869217 0.29 ENST00000264668.2
ENST00000514220.1
ENST00000341013.6
ENST00000440940.2
ENST00000502550.1
ENST00000506877.1
MTRR
5-methyltetrahydrofolate-homocysteine methyltransferase reductase
chr19_+_56652686 0.29 ENST00000592949.1
ZNF444
zinc finger protein 444
chr17_-_34808047 0.29 ENST00000592614.1
ENST00000591542.1
ENST00000330458.7
ENST00000341264.6
ENST00000592987.1
ENST00000400684.4
TBC1D3G
TBC1D3H
TBC1 domain family, member 3G
TBC1 domain family, member 3H
chr3_-_112218205 0.29 ENST00000383680.4
BTLA
B and T lymphocyte associated
chr16_-_67260691 0.28 ENST00000447579.1
ENST00000393992.1
ENST00000424285.1
LRRC29
leucine rich repeat containing 29
chr8_+_95653302 0.28 ENST00000423620.2
ENST00000433389.2
ESRP1
epithelial splicing regulatory protein 1
chr10_-_76995769 0.28 ENST00000372538.3
COMTD1
catechol-O-methyltransferase domain containing 1
chr12_-_25348007 0.28 ENST00000354189.5
ENST00000545133.1
ENST00000554347.1
ENST00000395987.3
ENST00000320267.9
ENST00000395990.2
ENST00000537577.1
CASC1
cancer susceptibility candidate 1
chr14_-_101295407 0.28 ENST00000596284.1
AL117190.2
AL117190.2
chr17_-_79359021 0.28 ENST00000572301.1
RP11-1055B8.3
RP11-1055B8.3
chr3_-_3151664 0.28 ENST00000256452.3
ENST00000311981.8
ENST00000430514.2
ENST00000456302.1
IL5RA
interleukin 5 receptor, alpha
chr10_+_99627889 0.27 ENST00000596005.1
GOLGA7B
Golgin subfamily A member 7B; cDNA FLJ43465 fis, clone OCBBF2036476
chr17_-_34807272 0.27 ENST00000535592.1
ENST00000394453.1
TBC1D3G
TBC1 domain family, member 3G
chr7_-_107770794 0.27 ENST00000205386.4
ENST00000418464.1
ENST00000388781.3
ENST00000388780.3
ENST00000414450.2
LAMB4
laminin, beta 4
chr17_-_36347835 0.27 ENST00000519532.1
TBC1D3
TBC1 domain family, member 3
chr1_+_52082751 0.27 ENST00000447887.1
ENST00000435686.2
ENST00000428468.1
ENST00000453295.1
OSBPL9
oxysterol binding protein-like 9

Network of associatons between targets according to the STRING database.

First level regulatory network of VDR

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
1.0 7.0 GO:0019557 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.9 2.7 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
0.8 2.4 GO:1901053 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.8 2.4 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.7 4.1 GO:0061107 seminal vesicle development(GO:0061107)
0.7 2.7 GO:0034444 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) phenylpropanoid catabolic process(GO:0046271)
0.7 2.0 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.6 2.5 GO:0042377 menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)
0.6 3.5 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.5 2.6 GO:0010902 positive regulation of very-low-density lipoprotein particle remodeling(GO:0010902)
0.3 1.0 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.3 1.0 GO:0006788 heme oxidation(GO:0006788) negative regulation of mast cell cytokine production(GO:0032764)
0.2 1.5 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.2 6.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 2.9 GO:0051918 negative regulation of smooth muscle cell apoptotic process(GO:0034392) negative regulation of fibrinolysis(GO:0051918)
0.2 0.9 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.2 0.8 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.2 1.6 GO:0042373 vitamin K metabolic process(GO:0042373)
0.2 0.9 GO:2000473 regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.2 0.5 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.2 0.5 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.2 1.9 GO:0035095 behavioral response to nicotine(GO:0035095)
0.1 0.4 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.1 4.9 GO:0051923 sulfation(GO:0051923)
0.1 0.6 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.1 2.5 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.1 0.8 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.3 GO:0001868 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.1 1.6 GO:0015747 urate transport(GO:0015747)
0.1 1.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 0.4 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.1 0.4 GO:0009386 translational attenuation(GO:0009386)
0.1 0.8 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.1 0.3 GO:1902530 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.1 0.4 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1 0.3 GO:0042369 vitamin D catabolic process(GO:0042369)
0.1 1.0 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1 0.9 GO:0034378 chylomicron assembly(GO:0034378)
0.1 0.7 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.1 2.2 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1 1.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 1.7 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.1 0.3 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.1 1.0 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.3 GO:0060032 notochord regression(GO:0060032)
0.1 0.4 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.1 0.3 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.1 0.2 GO:0002215 defense response to nematode(GO:0002215)
0.1 0.7 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 0.3 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.1 0.2 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.1 0.3 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.1 0.5 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.3 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.5 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.4 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.0 0.5 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.2 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
0.0 0.6 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.1 GO:0071264 regulation of eIF2 alpha phosphorylation by amino acid starvation(GO:0060733) regulation of translational initiation in response to starvation(GO:0071262) positive regulation of translational initiation in response to starvation(GO:0071264)
0.0 0.4 GO:0070269 pyroptosis(GO:0070269)
0.0 0.4 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.4 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.9 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 0.2 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.2 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.4 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.2 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.6 GO:0008595 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.2 GO:0070417 cellular response to cold(GO:0070417)
0.0 1.5 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 1.4 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 2.4 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.3 GO:0007498 mesoderm development(GO:0007498)
0.0 0.1 GO:0042427 serotonin biosynthetic process(GO:0042427)
0.0 0.6 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.3 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:0071672 negative regulation of smooth muscle cell chemotaxis(GO:0071672)
0.0 0.2 GO:0050893 sensory processing(GO:0050893)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 1.2 GO:0010107 potassium ion import(GO:0010107)
0.0 0.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.3 GO:0060068 vagina development(GO:0060068)
0.0 1.5 GO:0055092 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 0.1 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.3 GO:0000226 microtubule cytoskeleton organization(GO:0000226)
0.0 0.1 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.5 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.2 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.2 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 0.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.1 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 1.5 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.5 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 1.4 GO:0032411 positive regulation of transporter activity(GO:0032411)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.1 GO:0097181 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.9 3.7 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.4 4.5 GO:0005579 membrane attack complex(GO:0005579)
0.3 3.0 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.2 2.7 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.2 0.9 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.2 1.5 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.2 5.5 GO:0042627 chylomicron(GO:0042627)
0.2 1.5 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 0.9 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.1 1.9 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.8 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 1.5 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 3.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.4 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.4 GO:0005921 gap junction(GO:0005921)
0.0 2.2 GO:1903293 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 0.1 GO:0070826 paraferritin complex(GO:0070826)
0.0 3.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.4 GO:0043195 terminal bouton(GO:0043195)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.3 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.5 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 2.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:0004397 histidine ammonia-lyase activity(GO:0004397)
0.9 2.7 GO:0046573 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.8 2.4 GO:0008480 sarcosine dehydrogenase activity(GO:0008480)
0.8 5.5 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.6 1.9 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.6 3.0 GO:0016841 ammonia-lyase activity(GO:0016841)
0.5 2.0 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.5 2.7 GO:0017153 citrate transmembrane transporter activity(GO:0015137) succinate transmembrane transporter activity(GO:0015141) tricarboxylic acid transmembrane transporter activity(GO:0015142) sodium:dicarboxylate symporter activity(GO:0017153)
0.4 4.1 GO:0032190 acrosin binding(GO:0032190)
0.3 1.6 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.3 1.2 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) phosphatidate cytidylyltransferase activity(GO:0004605)
0.3 2.4 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.3 1.0 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.2 0.6 GO:0045485 omega-6 fatty acid desaturase activity(GO:0045485)
0.2 1.4 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.2 4.5 GO:0019841 retinol binding(GO:0019841)
0.2 4.9 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 1.5 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.8 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.7 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.1 0.9 GO:0070404 NADH binding(GO:0070404)
0.1 0.6 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.1 0.8 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 1.5 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 2.5 GO:0005243 gap junction channel activity(GO:0005243)
0.1 1.0 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.1 1.4 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.1 0.4 GO:0031716 calcitonin receptor binding(GO:0031716)
0.1 0.5 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 1.5 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 1.9 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 1.0 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 1.7 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.4 GO:0045569 TRAIL binding(GO:0045569)
0.1 0.3 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.1 1.9 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 0.5 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 0.3 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.1 1.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.7 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 2.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.3 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.1 0.5 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.5 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.6 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 2.5 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.9 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.1 GO:0002113 interleukin-33 binding(GO:0002113)
0.0 0.4 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.1 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.2 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.5 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.6 GO:0005522 profilin binding(GO:0005522)
0.0 0.4 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.3 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.4 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 3.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 2.0 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.7 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.9 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.5 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.1 GO:0015087 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.4 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 1.4 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 2.8 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.4 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.2 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.5 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.2 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.6 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.3 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.5 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.1 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 5.6 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.9 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.6 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 2.4 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.5 PID EPO PATHWAY EPO signaling pathway
0.0 0.3 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.0 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.9 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.4 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.2 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.4 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.0 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.6 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.6 PID NCADHERIN PATHWAY N-cadherin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.9 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 2.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 3.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 6.5 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 1.9 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 1.6 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 1.5 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.1 1.5 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 1.6 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 2.9 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.6 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.6 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.6 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 1.0 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 1.8 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.7 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 1.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.8 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.2 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 7.0 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.6 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.4 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.6 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.8 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.0 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.6 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.4 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.5 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.5 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.4 REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways