Project
Illumina Body Map 2: averaged replicates
Navigation
Downloads
Results for VSX1
Z-value: 1.37
Motif logo
Transcription factors associated with VSX1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| VSX1 | hg19_v2_chr20_-_25062767_25062779 | -0.60 | 2.8e-04 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of VSX1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.6 | GO:0036498 | IRE1-mediated unfolded protein response(GO:0036498) |
| 0.1 | 4.2 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 1.3 | 3.9 | GO:0071449 | cellular response to lipid hydroperoxide(GO:0071449) |
| 0.1 | 3.7 | GO:1902894 | negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894) |
| 0.1 | 3.5 | GO:0048240 | sperm capacitation(GO:0048240) |
| 0.8 | 3.3 | GO:0046338 | phosphatidylethanolamine catabolic process(GO:0046338) |
| 0.1 | 2.9 | GO:0006099 | tricarboxylic acid cycle(GO:0006099) |
| 0.0 | 2.7 | GO:0045454 | cell redox homeostasis(GO:0045454) |
| 0.6 | 2.4 | GO:0018352 | protein-pyridoxal-5-phosphate linkage(GO:0018352) |
| 0.2 | 2.1 | GO:0006572 | tyrosine catabolic process(GO:0006572) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.2 | GO:0045271 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.0 | 3.9 | GO:0035577 | azurophil granule membrane(GO:0035577) |
| 0.0 | 3.0 | GO:0048770 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.2 | 2.9 | GO:0097524 | sperm plasma membrane(GO:0097524) |
| 0.0 | 2.7 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.0 | 2.4 | GO:0018995 | host(GO:0018995) host cell(GO:0043657) |
| 0.1 | 2.3 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.1 | 2.3 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 0.0 | 2.1 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
| 0.1 | 2.0 | GO:0070775 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 4.3 | GO:0016864 | protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864) |
| 0.1 | 4.2 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.2 | 3.9 | GO:0043295 | glutathione binding(GO:0043295) |
| 0.2 | 3.3 | GO:0047499 | calcium-independent phospholipase A2 activity(GO:0047499) |
| 0.2 | 2.9 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 0.0 | 2.5 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.2 | 2.4 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
| 0.1 | 2.4 | GO:0070410 | co-SMAD binding(GO:0070410) |
| 0.0 | 2.4 | GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980) |
| 0.1 | 2.3 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.5 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.0 | 3.2 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.1 | 3.0 | SA TRKA RECEPTOR | The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth. |
| 0.0 | 1.7 | PID MET PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
| 0.1 | 1.6 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.0 | 1.6 | PID ATR PATHWAY | ATR signaling pathway |
| 0.0 | 1.4 | SIG IL4RECEPTOR IN B LYPHOCYTES | Genes related to IL4 rceptor signaling in B lymphocytes |
| 0.0 | 1.4 | PID THROMBIN PAR1 PATHWAY | PAR1-mediated thrombin signaling events |
| 0.0 | 1.4 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
| 0.0 | 1.1 | PID PTP1B PATHWAY | Signaling events mediated by PTP1B |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 5.1 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.1 | 3.9 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.0 | 3.2 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
| 0.0 | 2.5 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.0 | 2.5 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.1 | 2.4 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.0 | 2.3 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.1 | 2.2 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.1 | 2.1 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
| 0.1 | 2.1 | REACTOME SIGNAL ATTENUATION | Genes involved in Signal attenuation |