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Illumina Body Map 2: averaged replicates

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Results for ZBTB12

Z-value: 1.53

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Transcription factors associated with ZBTB12

Gene Symbol Gene ID Gene Info
ENSG00000204366.3 zinc finger and BTB domain containing 12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZBTB12hg19_v2_chr6_-_31869769_31869880-0.105.8e-01Click!

Activity profile of ZBTB12 motif

Sorted Z-values of ZBTB12 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_26644441 5.84 ENST00000374213.2
CD52 molecule
chr7_-_142139783 4.60 ENST00000390374.3
T cell receptor beta variable 7-6
chr19_+_52264449 4.33 ENST00000599326.1
ENST00000598953.1
formyl peptide receptor 2
chr7_-_142247606 3.86 ENST00000390361.3
T cell receptor beta variable 7-3
chr13_-_46716969 3.36 ENST00000435666.2
lymphocyte cytosolic protein 1 (L-plastin)
chr1_-_200992827 3.28 ENST00000332129.2
ENST00000422435.2
kinesin family member 21B
chr3_-_72149553 3.24 ENST00000468646.2
ENST00000464271.1
long intergenic non-protein coding RNA 877
chr1_+_158901329 3.20 ENST00000368140.1
ENST00000368138.3
ENST00000392254.2
ENST00000392252.3
ENST00000368135.4
pyrin and HIN domain family, member 1
chr5_+_54320078 3.07 ENST00000231009.2
granzyme K (granzyme 3; tryptase II)
chr3_-_72149448 3.02 ENST00000498432.1
long intergenic non-protein coding RNA 877
chr14_+_22204418 2.95 ENST00000390426.2
T cell receptor alpha variable 4
chr1_-_32264356 2.92 ENST00000452755.2
SPOC domain containing 1
chr3_-_151047327 2.79 ENST00000325602.5
purinergic receptor P2Y, G-protein coupled, 13
chr2_+_89999259 2.74 ENST00000558026.1
immunoglobulin kappa variable 2D-28
chr15_+_81475047 2.68 ENST00000559388.1
interleukin 16
chr14_+_22564294 2.67 ENST00000390452.2
T cell receptor delta variable 1
chr10_+_23216944 2.60 ENST00000298032.5
ENST00000409983.3
ENST00000409049.3
armadillo repeat containing 3
chr19_+_55417530 2.52 ENST00000350790.5
ENST00000338835.5
ENST00000357397.5
natural cytotoxicity triggering receptor 1
chr12_+_8608522 2.51 ENST00000382073.3
C-type lectin domain family 6, member A
chr11_-_59952106 2.50 ENST00000529054.1
ENST00000530839.1
membrane-spanning 4-domains, subfamily A, member 6A
chr7_-_142176790 2.47 ENST00000390369.2
T cell receptor beta variable 7-4 (gene/pseudogene)
chr11_+_63273547 2.38 ENST00000255684.5
ENST00000394618.3
lectin, galactoside-binding, soluble, 12
chr22_+_38035459 2.34 ENST00000357436.4
SH3-domain binding protein 1
chr10_+_23217006 2.24 ENST00000376528.4
ENST00000447081.1
armadillo repeat containing 3
chr22_+_22930626 2.18 ENST00000390302.2
immunoglobulin lambda variable 2-33 (non-functional)
chr19_+_55417499 2.12 ENST00000291890.4
ENST00000447255.1
ENST00000598576.1
ENST00000594765.1
natural cytotoxicity triggering receptor 1
chr8_+_38758737 2.09 ENST00000521746.1
ENST00000420274.1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
chr11_-_104972158 1.93 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr4_-_40632881 1.90 ENST00000511598.1
RNA binding motif protein 47
chr11_-_59951889 1.77 ENST00000532169.1
ENST00000534596.1
membrane-spanning 4-domains, subfamily A, member 6A
chr22_-_50524298 1.75 ENST00000311597.5
megalencephalic leukoencephalopathy with subcortical cysts 1
chr11_-_59951955 1.74 ENST00000531531.1
membrane-spanning 4-domains, subfamily A, member 6A
chr6_-_130182410 1.68 ENST00000368143.1
transmembrane protein 244
chr22_-_50523843 1.59 ENST00000535444.1
ENST00000431262.2
megalencephalic leukoencephalopathy with subcortical cysts 1
chr22_-_50523807 1.56 ENST00000442311.1
ENST00000538737.1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr11_-_104905840 1.53 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
caspase 1, apoptosis-related cysteine peptidase
chr14_+_22471345 1.53 ENST00000390446.3
T cell receptor alpha variable 18
chr14_+_22995812 1.47 ENST00000390520.1
T cell receptor alpha joining 17
chr11_+_63273811 1.41 ENST00000340246.5
lectin, galactoside-binding, soluble, 12
chr11_+_60145967 1.40 ENST00000534016.1
membrane-spanning 4-domains, subfamily A, member 7
chrX_+_133930798 1.40 ENST00000414371.2
family with sequence similarity 122C
chr4_-_40632605 1.37 ENST00000514014.1
RNA binding motif protein 47
chr6_+_147527103 1.37 ENST00000179882.6
syntaxin binding protein 5 (tomosyn)
chr1_-_109203997 1.33 ENST00000370032.5
HEN1 methyltransferase homolog 1 (Arabidopsis)
chr6_+_36097992 1.31 ENST00000211287.4
mitogen-activated protein kinase 13
chr14_+_22965872 1.29 ENST00000390495.1
T cell receptor alpha joining 42
chr1_+_158979792 1.29 ENST00000359709.3
ENST00000430894.2
interferon, gamma-inducible protein 16
chr16_-_67969888 1.28 ENST00000574576.2
proteasome (prosome, macropain) subunit, beta type, 10
chr11_+_60145997 1.28 ENST00000530614.1
ENST00000530027.1
ENST00000530234.2
ENST00000528215.1
ENST00000531787.1
membrane-spanning 4-domains, subfamily A, member 7
membrane-spanning 4-domains, subfamily A, member 14
chr11_+_72525353 1.27 ENST00000321297.5
ENST00000534905.1
ENST00000540567.1
autophagy related 16-like 2 (S. cerevisiae)
chr17_-_5487768 1.26 ENST00000269280.4
ENST00000345221.3
ENST00000262467.5
NLR family, pyrin domain containing 1
chr7_+_12544025 1.25 ENST00000443874.1
ENST00000424453.1
AC005281.1
chr11_+_22646739 1.24 ENST00000428556.2
AC103801.2
chr4_-_40632757 1.20 ENST00000511902.1
ENST00000505220.1
RNA binding motif protein 47
chr19_-_11688500 1.18 ENST00000433365.2
acid phosphatase 5, tartrate resistant
chr11_+_60145948 1.17 ENST00000300184.3
ENST00000358246.1
membrane-spanning 4-domains, subfamily A, member 7
chr13_-_37633743 1.15 ENST00000497318.1
ENST00000475892.1
ENST00000356185.3
ENST00000350612.6
ENST00000542180.1
ENST00000360252.4
suppressor of Ty 20 homolog (S. cerevisiae)
chr15_-_55563072 1.13 ENST00000567380.1
ENST00000565972.1
ENST00000569493.1
RAB27A, member RAS oncogene family
chr15_-_55562479 1.12 ENST00000564609.1
RAB27A, member RAS oncogene family
chr14_-_74959978 1.09 ENST00000541064.1
Niemann-Pick disease, type C2
chrX_-_133931164 1.09 ENST00000370790.1
ENST00000298090.6
family with sequence similarity 122B
chrX_-_131353461 1.07 ENST00000370874.1
RAP2C, member of RAS oncogene family
chr15_-_55562451 1.06 ENST00000568803.1
RAB27A, member RAS oncogene family
chr14_-_74960030 1.05 ENST00000553490.1
ENST00000557510.1
Niemann-Pick disease, type C2
chr15_-_55562582 1.03 ENST00000396307.2
RAB27A, member RAS oncogene family
chr1_-_157522180 1.03 ENST00000356953.4
ENST00000368188.2
ENST00000368190.3
ENST00000368189.3
Fc receptor-like 5
chr6_+_140175987 1.03 ENST00000414038.1
ENST00000431609.1
RP5-899B16.1
chr1_+_158979680 1.01 ENST00000368131.4
ENST00000340979.6
interferon, gamma-inducible protein 16
chr3_-_157217328 1.00 ENST00000392832.2
ENST00000543418.1
ventricular zone expressed PH domain-containing 1
chr4_-_40632844 0.98 ENST00000505414.1
RNA binding motif protein 47
chr1_+_158979686 0.98 ENST00000368132.3
ENST00000295809.7
interferon, gamma-inducible protein 16
chr19_+_11457232 0.95 ENST00000587531.1
coiled-coil domain containing 159
chr19_-_11688951 0.90 ENST00000589792.1
acid phosphatase 5, tartrate resistant
chr1_+_100503643 0.89 ENST00000370152.3
hippocampus abundant transcript 1
chrX_+_41548259 0.86 ENST00000378138.5
G protein-coupled receptor 34
chr14_-_74959994 0.86 ENST00000238633.2
ENST00000434013.2
Niemann-Pick disease, type C2
chr12_-_62586543 0.85 ENST00000416284.3
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
chrX_+_149861836 0.85 ENST00000542156.1
ENST00000370390.3
ENST00000490316.2
ENST00000445323.2
ENST00000544228.1
ENST00000451863.2
myotubularin related protein 1
chr13_+_97928395 0.84 ENST00000445661.2
muscleblind-like splicing regulator 2
chr17_-_4643161 0.83 ENST00000574412.1
chemokine (C-X-C motif) ligand 16
chr7_+_129984630 0.83 ENST00000355388.3
ENST00000497503.1
ENST00000463587.1
ENST00000461828.1
ENST00000494311.1
ENST00000466363.2
ENST00000485477.1
ENST00000431780.2
ENST00000474905.1
carboxypeptidase A5
chr4_-_36246060 0.82 ENST00000303965.4
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr17_-_61781750 0.81 ENST00000582026.1
STE20-related kinase adaptor alpha
chr1_-_198990166 0.80 ENST00000427439.1
RP11-16L9.3
chr21_-_32253874 0.79 ENST00000332378.4
keratin associated protein 11-1
chr11_-_59951430 0.78 ENST00000533409.1
membrane-spanning 4-domains, subfamily A, member 6A
chr3_-_49837254 0.77 ENST00000412678.2
ENST00000343366.4
ENST00000487256.1
cadherin-related family member 4
chr15_+_40453204 0.77 ENST00000287598.6
ENST00000412359.3
BUB1 mitotic checkpoint serine/threonine kinase B
chr2_-_214013353 0.73 ENST00000451136.2
ENST00000421754.2
ENST00000374327.4
ENST00000413091.3
IKAROS family zinc finger 2 (Helios)
chr8_+_118533049 0.73 ENST00000522839.1
mediator complex subunit 30
chrX_+_70338525 0.70 ENST00000374102.1
mediator complex subunit 12
chr11_+_74303612 0.69 ENST00000527458.1
ENST00000532497.1
ENST00000530511.1
polymerase (DNA-directed), delta 3, accessory subunit
chr5_-_88179302 0.69 ENST00000504921.2
myocyte enhancer factor 2C
chr14_-_22938665 0.67 ENST00000535880.2
T cell receptor delta variable 3
chr11_+_74303575 0.67 ENST00000263681.2
polymerase (DNA-directed), delta 3, accessory subunit
chr10_+_90660832 0.66 ENST00000371924.1
STAM binding protein-like 1
chr14_-_91526462 0.65 ENST00000536315.2
ribosomal protein S6 kinase, 90kDa, polypeptide 5
chr11_-_65769594 0.65 ENST00000532707.1
ENST00000533544.1
ENST00000526451.1
ENST00000312234.2
ENST00000530462.1
ENST00000525767.1
ENST00000529964.1
ENST00000527249.1
eukaryotic translation initiation factor 1A domain containing
chrX_-_24690771 0.64 ENST00000379145.1
phosphate cytidylyltransferase 1, choline, beta
chr4_+_26859300 0.64 ENST00000494628.2
stromal interaction molecule 2
chr15_+_66797627 0.63 ENST00000565627.1
ENST00000564179.1
zwilch kinetochore protein
chr4_+_139694701 0.61 ENST00000502606.1
RP11-98O2.1
chr1_+_200993071 0.61 ENST00000446333.1
ENST00000458003.1
RP11-168O16.1
chr15_+_66797455 0.61 ENST00000446801.2
zwilch kinetochore protein
chr3_-_190167571 0.61 ENST00000354905.2
transmembrane protein 207
chr3_-_50336548 0.59 ENST00000450489.1
ENST00000513170.1
ENST00000450982.1
N-acetyltransferase 6 (GCN5-related)
hyaluronoglucosaminidase 3
chr5_-_88178964 0.58 ENST00000513252.1
ENST00000508569.1
ENST00000510942.1
ENST00000506554.1
myocyte enhancer factor 2C
chr11_-_62323702 0.57 ENST00000530285.1
AHNAK nucleoprotein
chr18_-_47018769 0.56 ENST00000583637.1
ENST00000578528.1
ENST00000578532.1
ENST00000580387.1
ENST00000579248.1
ENST00000581373.1
ribosomal protein L17
chr12_+_49658855 0.56 ENST00000549183.1
tubulin, alpha 1c
chr1_+_155583012 0.55 ENST00000462250.2
misato 1, mitochondrial distribution and morphology regulator
chr3_-_50336826 0.54 ENST00000443842.1
ENST00000354862.4
ENST00000443094.2
ENST00000415204.1
ENST00000336307.1
N-acetyltransferase 6 (GCN5-related)
hyaluronoglucosaminidase 3
chr1_+_32757668 0.53 ENST00000373548.3
histone deacetylase 1
chr19_+_44716768 0.52 ENST00000586048.1
zinc finger protein 227
chr19_-_6767516 0.50 ENST00000245908.6
SH2 domain containing 3A
chr20_+_36373032 0.49 ENST00000373473.1
catenin, beta like 1
chr19_+_58258164 0.48 ENST00000317178.5
zinc finger protein 776
chr19_+_44716678 0.47 ENST00000586228.1
ENST00000588219.1
ENST00000313040.7
ENST00000589707.1
ENST00000588394.1
ENST00000589005.1
zinc finger protein 227
chr8_+_118532937 0.47 ENST00000297347.3
mediator complex subunit 30
chr5_-_88179017 0.46 ENST00000514028.1
ENST00000514015.1
ENST00000503075.1
ENST00000437473.2
myocyte enhancer factor 2C
chr17_+_11501748 0.46 ENST00000262442.4
ENST00000579828.1
dynein, axonemal, heavy chain 9
chr12_-_46766577 0.45 ENST00000256689.5
solute carrier family 38, member 2
chr9_-_28026318 0.44 ENST00000308675.3
leucine rich repeat and Ig domain containing 2
chr19_+_11485333 0.44 ENST00000312423.2
SWIM-type zinc finger 7 associated protein 1
chr11_+_8704748 0.43 ENST00000526562.1
ENST00000525981.1
ribosomal protein L27a
chr11_+_65769946 0.43 ENST00000533166.1
barrier to autointegration factor 1
chr19_-_51531210 0.43 ENST00000391804.3
kallikrein-related peptidase 11
chr15_-_66797172 0.42 ENST00000569438.1
ENST00000569696.1
ENST00000307961.6
ribosomal protein L4
chr11_+_63449045 0.40 ENST00000354497.4
reticulon 3
chr9_+_127615733 0.40 ENST00000373574.1
WD repeat domain 38
chr9_+_123884038 0.40 ENST00000373847.1
centriolin
chr17_+_46184911 0.40 ENST00000580219.1
ENST00000452859.2
ENST00000393405.2
ENST00000439357.2
ENST00000359238.2
sorting nexin 11
chr6_+_2988933 0.40 ENST00000597787.1
long intergenic non-protein coding RNA 1011
chr19_+_52873166 0.39 ENST00000424032.2
ENST00000600321.1
ENST00000344085.5
ENST00000597976.1
ENST00000422689.2
zinc finger protein 880
chr17_+_4643337 0.38 ENST00000592813.1
zinc finger, MYND-type containing 15
chr17_-_7142725 0.38 ENST00000571362.1
ENST00000576955.1
ENST00000320316.3
PHD finger protein 23
chr20_+_2854066 0.38 ENST00000455631.1
ENST00000216877.6
ENST00000399903.2
ENST00000358719.4
ENST00000431048.1
ENST00000425918.2
ENST00000430705.1
ENST00000318266.5
protein tyrosine phosphatase, receptor type, A
chr19_-_51531272 0.38 ENST00000319720.7
kallikrein-related peptidase 11
chr1_+_22778337 0.37 ENST00000404138.1
ENST00000400239.2
ENST00000375647.4
ENST00000374651.4
zinc finger and BTB domain containing 40
chr19_-_6767431 0.36 ENST00000437152.3
ENST00000597687.1
SH2 domain containing 3A
chr4_-_10118348 0.35 ENST00000502702.1
WD repeat domain 1
chr19_-_51530916 0.35 ENST00000594768.1
kallikrein-related peptidase 11
chr12_+_53689309 0.34 ENST00000351500.3
ENST00000550846.1
ENST00000334478.4
ENST00000549759.1
prefoldin subunit 5
chr6_-_52926539 0.34 ENST00000350082.5
ENST00000356971.3
intestinal cell (MAK-like) kinase
chr20_-_8000426 0.33 ENST00000527925.1
ENST00000246024.2
thioredoxin-related transmembrane protein 4
chr1_+_11838988 0.32 ENST00000444493.1
chromosome 1 open reading frame 167
chr12_+_14572070 0.32 ENST00000545769.1
ENST00000428217.2
ENST00000396279.2
ENST00000542514.1
ENST00000536279.1
activating transcription factor 7 interacting protein
chr18_-_53177984 0.31 ENST00000543082.1
transcription factor 4
chr12_-_123565834 0.31 ENST00000546049.1
phosphatidylinositol transfer protein, membrane-associated 2
chr13_+_42712178 0.30 ENST00000536612.1
diacylglycerol kinase, eta
chr4_+_139694723 0.30 ENST00000513400.1
RP11-98O2.1
chr1_-_94344686 0.30 ENST00000528680.1
deoxynucleotidyltransferase, terminal, interacting protein 2
chr14_+_22966642 0.30 ENST00000390496.1
T cell receptor alpha joining 41
chr5_+_148443049 0.29 ENST00000515304.1
ENST00000507318.1
CTC-529P8.1
chr11_-_68611721 0.28 ENST00000561996.1
carnitine palmitoyltransferase 1A (liver)
chr1_+_45212051 0.28 ENST00000372222.3
kinesin family member 2C
chr1_-_185597619 0.27 ENST00000608417.1
ENST00000436955.1
GS1-204I12.1
chr5_+_148443113 0.26 ENST00000507373.1
CTC-529P8.1
chr14_+_101359265 0.26 ENST00000599197.1
Esophagus cancer-related gene-2 interaction susceptibility protein; Uncharacterized protein
chr12_+_72080253 0.25 ENST00000549735.1
transmembrane protein 19
chr14_-_54908043 0.23 ENST00000556113.1
ENST00000553660.1
ENST00000395573.4
ENST00000557690.1
ENST00000216416.4
cornichon family AMPA receptor auxiliary protein 1
chr19_+_46195895 0.23 ENST00000366382.4
glutaminyl-peptide cyclotransferase-like
chr1_+_113010056 0.22 ENST00000369686.5
wingless-type MMTV integration site family, member 2B
chrX_+_101478829 0.22 ENST00000372763.1
ENST00000372758.1
nuclear RNA export factor 2
chr20_-_43248126 0.21 ENST00000597250.1
Uncharacterized protein
chrX_-_122866874 0.21 ENST00000245838.8
ENST00000355725.4
THO complex 2
chr9_-_26946981 0.20 ENST00000523212.1
phospholipase A2-activating protein
chr1_+_100598742 0.19 ENST00000370139.1
tRNA methyltransferase 13 homolog (S. cerevisiae)
chr12_-_56321649 0.19 ENST00000454792.2
ENST00000408946.2
within bgcn homolog (Drosophila)
chr19_+_58258202 0.18 ENST00000431353.1
zinc finger protein 776
chr7_+_48211048 0.18 ENST00000435803.1
ATP-binding cassette, sub-family A (ABC1), member 13
chr16_+_53412368 0.18 ENST00000565189.1
RP11-44F14.2
chr12_-_7077125 0.18 ENST00000545555.2
prohibitin 2
chr12_+_123459127 0.18 ENST00000397389.2
ENST00000538755.1
ENST00000536150.1
ENST00000545056.1
ENST00000545612.1
ENST00000538628.1
ENST00000545317.1
2-oxoglutarate and iron-dependent oxygenase domain containing 2
chr1_+_171107241 0.17 ENST00000236166.3
flavin containing monooxygenase 6 pseudogene
chr17_+_36908984 0.17 ENST00000225426.4
ENST00000579088.1
proteasome (prosome, macropain) subunit, beta type, 3
chr7_+_92158083 0.16 ENST00000265732.5
ENST00000481551.1
ENST00000496410.1
RNA binding motif protein 48
chr3_-_52804872 0.15 ENST00000535191.1
ENST00000461689.1
ENST00000383721.4
ENST00000233027.5
NIMA-related kinase 4
chr17_-_39677971 0.15 ENST00000393976.2
keratin 15
chr1_+_45212074 0.15 ENST00000372217.1
kinesin family member 2C
chr6_-_114292449 0.15 ENST00000519065.1
histone deacetylase 2
chr7_+_23637763 0.15 ENST00000410069.1
coiled-coil domain containing 126
chr13_+_24144509 0.13 ENST00000248484.4
tumor necrosis factor receptor superfamily, member 19
chr17_+_46185111 0.12 ENST00000582104.1
ENST00000584335.1
sorting nexin 11
chr14_-_62162541 0.12 ENST00000557544.1
HIF1A antisense RNA 1
chr5_-_35089722 0.12 ENST00000511486.1
ENST00000310101.5
ENST00000231423.3
ENST00000513753.1
ENST00000348262.3
ENST00000397391.3
ENST00000542609.1
prolactin receptor
chr13_+_46039037 0.11 ENST00000349995.5
component of oligomeric golgi complex 3
chr12_+_49208234 0.11 ENST00000540990.1
calcium channel, voltage-dependent, beta 3 subunit
chr20_-_44718538 0.10 ENST00000290231.6
ENST00000372291.3
nuclear receptor coactivator 5
chr9_-_80437915 0.09 ENST00000397476.3
guanine nucleotide binding protein (G protein), q polypeptide
chr14_-_96743060 0.08 ENST00000554299.1
DKFZP434O1614
chrX_+_50653784 0.08 ENST00000252677.3
bone morphogenetic protein 15
chr8_+_104892639 0.07 ENST00000436393.2
regulating synaptic membrane exocytosis 2
chr19_-_46148820 0.06 ENST00000587152.1
echinoderm microtubule associated protein like 2
chr20_-_25320367 0.05 ENST00000450393.1
ENST00000491682.1
abhydrolase domain containing 12
chr3_+_101818088 0.05 ENST00000491959.1
zona pellucida-like domain containing 1
chr11_+_65769550 0.05 ENST00000312175.2
ENST00000445560.2
ENST00000530204.1
barrier to autointegration factor 1
chr1_+_59486059 0.05 ENST00000447329.1
RP4-794H19.4
chr15_-_49912987 0.05 ENST00000560246.1
ENST00000558594.1
family with sequence similarity 227, member B
chr6_-_160209471 0.04 ENST00000539948.1
t-complex 1

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB12

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.5 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.6 4.3 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.5 3.0 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.4 1.3 GO:1904784 NLRP1 inflammasome complex assembly(GO:1904784)
0.4 5.5 GO:0016554 cytidine to uridine editing(GO:0016554)
0.3 2.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.2 1.7 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.2 4.3 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.2 4.9 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.2 1.3 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.2 0.8 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.1 5.8 GO:0045730 respiratory burst(GO:0045730)
0.1 3.7 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 3.4 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 0.7 GO:0043988 histone H3-S28 phosphorylation(GO:0043988) histone H2A phosphorylation(GO:1990164)
0.1 2.7 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.1 0.7 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.1 0.4 GO:0042247 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.1 4.6 GO:0042269 regulation of natural killer cell mediated cytotoxicity(GO:0042269)
0.1 0.7 GO:0061198 fungiform papilla formation(GO:0061198)
0.1 0.4 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 0.2 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.1 0.3 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.1 3.3 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.1 0.6 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.6 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 2.5 GO:0050832 defense response to fungus(GO:0050832)
0.0 1.3 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.2 GO:0060492 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.0 4.1 GO:0050994 regulation of lipid catabolic process(GO:0050994)
0.0 1.1 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.9 GO:0071493 cellular response to UV-B(GO:0071493)
0.0 0.4 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.4 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.2 GO:0042695 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0 0.5 GO:0032328 alanine transport(GO:0032328)
0.0 0.5 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.8 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 1.4 GO:0006297 DNA ligation(GO:0006266) nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0 2.9 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.5 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 4.2 GO:0002377 immunoglobulin production(GO:0002377)
0.0 2.7 GO:0030449 regulation of complement activation(GO:0030449)
0.0 0.9 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 2.1 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.4 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.3 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 1.2 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.7 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 1.5 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.0 0.2 GO:0001302 replicative cell aging(GO:0001302)
0.0 0.1 GO:0052651 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.6 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.0 0.2 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.7 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.7 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.3 1.2 GO:1990423 RZZ complex(GO:1990423)
0.2 4.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.2 1.4 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 4.6 GO:0016514 SWI/SNF complex(GO:0016514)
0.1 1.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.4 GO:0097196 Shu complex(GO:0097196)
0.1 3.4 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.4 GO:0042643 actomyosin, actin portion(GO:0042643)
0.1 1.2 GO:0000124 SAGA complex(GO:0000124)
0.0 1.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.8 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.0 1.3 GO:0043186 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.3 GO:0016272 prefoldin complex(GO:0016272)
0.0 5.4 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 3.7 GO:0005871 kinesin complex(GO:0005871)
0.0 1.9 GO:0016592 mediator complex(GO:0016592)
0.0 0.2 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 4.4 GO:0005901 caveola(GO:0005901)
0.0 1.3 GO:0000421 autophagosome membrane(GO:0000421)
0.0 5.6 GO:0031225 anchored component of membrane(GO:0031225)
0.0 3.0 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.5 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.7 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.2 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.2 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 10.8 GO:0016607 nuclear speck(GO:0016607)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0030395 lactose binding(GO:0030395)
0.5 4.3 GO:0005124 N-formyl peptide receptor activity(GO:0004982) scavenger receptor binding(GO:0005124)
0.2 1.1 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.2 4.6 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.1 3.7 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.6 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 4.3 GO:0031489 myosin V binding(GO:0031489)
0.1 2.1 GO:0008199 ferric iron binding(GO:0008199)
0.1 0.3 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.1 2.7 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 1.9 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 1.7 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.2 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.1 0.2 GO:0016005 phospholipase A2 activator activity(GO:0016005)
0.1 0.9 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 2.1 GO:0001968 fibronectin binding(GO:0001968)
0.0 1.5 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.4 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 1.3 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.7 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 3.0 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 5.0 GO:0008565 protein transporter activity(GO:0008565)
0.0 3.7 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.8 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 1.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.6 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.7 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 6.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.2 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 1.1 GO:0019003 GDP binding(GO:0019003)
0.0 4.1 GO:0005057 receptor signaling protein activity(GO:0005057)
0.0 3.1 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.3 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.8 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.6 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 1.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 4.3 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 2.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.5 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 6.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 2.1 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.9 PID ARF6 PATHWAY Arf6 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 4.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.4 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 1.3 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 1.9 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 1.3 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 0.5 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 1.4 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 1.1 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.8 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 5.2 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 2.1 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.5 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0 0.9 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.6 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.5 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 1.9 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.9 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane