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Illumina Body Map 2: averaged replicates

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Results for ZBTB3

Z-value: 1.38

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Transcription factors associated with ZBTB3

Gene Symbol Gene ID Gene Info
ZBTB3
ENSG00000185670.7 zinc finger and BTB domain containing 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZBTB3hg19_v2_chr11_-_62521614_625216600.232.1e-01Click!

Activity profile of ZBTB3 motif

Sorted Z-values of ZBTB3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_41122063 4.10 ENST00000426005.2
ENST00000437044.2
ENST00000373127.4
TREML1
triggering receptor expressed on myeloid cells-like 1
chr3_-_39322728 4.07 ENST00000541347.1
ENST00000412814.1
CX3CR1
chemokine (C-X3-C motif) receptor 1
chr12_-_62586543 3.61 ENST00000416284.3
FAM19A2
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
chr6_+_123100620 3.13 ENST00000368444.3
FABP7
fatty acid binding protein 7, brain
chr4_+_159122728 2.93 ENST00000505049.1
ENST00000505189.1
ENST00000511038.1
TMEM144
transmembrane protein 144
chr6_+_12958137 2.89 ENST00000457702.2
ENST00000379345.2
PHACTR1
phosphatase and actin regulator 1
chr18_+_32073253 2.78 ENST00000283365.9
ENST00000596745.1
ENST00000315456.6
DTNA
dystrobrevin, alpha
chrX_+_152224766 2.67 ENST00000370265.4
ENST00000447306.1
PNMA3
paraneoplastic Ma antigen 3
chr5_-_82969405 2.55 ENST00000510978.1
HAPLN1
hyaluronan and proteoglycan link protein 1
chr21_-_48024986 2.32 ENST00000291700.4
ENST00000367071.4
S100B
S100 calcium binding protein B
chr5_-_149669612 2.25 ENST00000510347.1
CAMK2A
calcium/calmodulin-dependent protein kinase II alpha
chr16_+_24266874 2.25 ENST00000005284.3
CACNG3
calcium channel, voltage-dependent, gamma subunit 3
chr1_-_111148969 2.01 ENST00000316361.4
KCNA2
potassium voltage-gated channel, shaker-related subfamily, member 2
chrX_+_70364667 1.95 ENST00000536169.1
ENST00000395855.2
ENST00000374051.3
ENST00000358741.3
NLGN3
neuroligin 3
chr12_+_48577366 1.86 ENST00000316554.3
C12orf68
chromosome 12 open reading frame 68
chr19_-_19006920 1.83 ENST00000429504.2
ENST00000427170.2
CERS1
ceramide synthase 1
chr6_+_30850697 1.82 ENST00000509639.1
ENST00000412274.2
ENST00000507901.1
ENST00000507046.1
ENST00000437124.2
ENST00000454612.2
ENST00000396342.2
DDR1
discoidin domain receptor tyrosine kinase 1
chr16_+_87636474 1.80 ENST00000284262.2
JPH3
junctophilin 3
chr19_-_19006890 1.80 ENST00000247005.6
GDF1
growth differentiation factor 1
chr14_+_32964258 1.79 ENST00000556638.1
AKAP6
A kinase (PRKA) anchor protein 6
chr3_-_149688971 1.72 ENST00000498307.1
ENST00000489155.1
PFN2
profilin 2
chr1_-_111148241 1.72 ENST00000440270.1
KCNA2
potassium voltage-gated channel, shaker-related subfamily, member 2
chr6_+_30850862 1.71 ENST00000504651.1
ENST00000512694.1
ENST00000515233.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr16_-_19896150 1.54 ENST00000570142.1
GPRC5B
G protein-coupled receptor, family C, group 5, member B
chr3_+_98250743 1.50 ENST00000284311.3
GPR15
G protein-coupled receptor 15
chr5_+_75378997 1.42 ENST00000502798.2
SV2C
synaptic vesicle glycoprotein 2C
chr6_+_123100853 1.40 ENST00000356535.4
FABP7
fatty acid binding protein 7, brain
chr11_+_26353664 1.35 ENST00000531646.1
ANO3
anoctamin 3
chr5_+_112074029 1.32 ENST00000512211.2
APC
adenomatous polyposis coli
chr2_-_40679148 1.27 ENST00000417271.1
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr5_+_138609441 1.27 ENST00000509990.1
ENST00000506147.1
ENST00000512107.1
MATR3
matrin 3
chr17_-_17109579 1.14 ENST00000321560.3
PLD6
phospholipase D family, member 6
chr7_+_100081542 1.13 ENST00000300179.2
ENST00000423930.1
NYAP1
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 1
chr8_+_38261880 1.13 ENST00000527175.1
LETM2
leucine zipper-EF-hand containing transmembrane protein 2
chr13_-_48612067 1.13 ENST00000543413.1
SUCLA2
succinate-CoA ligase, ADP-forming, beta subunit
chr2_-_40679186 1.10 ENST00000406785.2
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr5_-_94417339 1.10 ENST00000429576.2
ENST00000508509.1
ENST00000510732.1
MCTP1
multiple C2 domains, transmembrane 1
chr1_+_160160346 1.10 ENST00000368078.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr17_+_75542997 1.09 ENST00000592651.1
ENST00000590398.1
RP11-13K12.1
RP11-13K12.1
chr5_-_94417186 1.08 ENST00000312216.8
ENST00000512425.1
MCTP1
multiple C2 domains, transmembrane 1
chr1_+_159141397 1.08 ENST00000368124.4
ENST00000368125.4
ENST00000416746.1
CADM3
cell adhesion molecule 3
chr14_+_22538811 1.05 ENST00000390450.3
TRAV22
T cell receptor alpha variable 22
chr1_+_160121356 1.04 ENST00000368081.4
ATP1A4
ATPase, Na+/K+ transporting, alpha 4 polypeptide
chr10_-_73533255 1.01 ENST00000394957.3
C10orf54
chromosome 10 open reading frame 54
chr19_-_40023450 1.00 ENST00000326282.4
EID2B
EP300 interacting inhibitor of differentiation 2B
chr3_-_149688502 1.00 ENST00000481767.1
ENST00000475518.1
PFN2
profilin 2
chr5_-_94417314 0.99 ENST00000505208.1
MCTP1
multiple C2 domains, transmembrane 1
chr16_+_30034655 0.98 ENST00000300575.2
C16orf92
chromosome 16 open reading frame 92
chr5_-_94417562 0.97 ENST00000505465.1
MCTP1
multiple C2 domains, transmembrane 1
chr1_+_155146318 0.94 ENST00000368385.4
ENST00000545012.1
ENST00000392451.2
ENST00000368383.3
ENST00000368382.1
ENST00000334634.4
TRIM46
tripartite motif containing 46
chr16_-_68406161 0.94 ENST00000568373.1
ENST00000563226.1
SMPD3
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
chr11_-_82782952 0.89 ENST00000534141.1
RAB30
RAB30, member RAS oncogene family
chr3_-_149688896 0.86 ENST00000239940.7
PFN2
profilin 2
chr19_-_49496557 0.85 ENST00000323798.3
ENST00000541188.1
ENST00000544287.1
ENST00000540532.1
ENST00000263276.6
GYS1
glycogen synthase 1 (muscle)
chr16_-_19896220 0.84 ENST00000562469.1
ENST00000300571.2
GPRC5B
G protein-coupled receptor, family C, group 5, member B
chr9_+_72002837 0.77 ENST00000377216.3
FAM189A2
family with sequence similarity 189, member A2
chr11_-_82782861 0.75 ENST00000524635.1
ENST00000526205.1
ENST00000527633.1
ENST00000533486.1
ENST00000533276.2
RAB30
RAB30, member RAS oncogene family
chr7_-_38403077 0.75 ENST00000426402.2
TRGV2
T cell receptor gamma variable 2
chr4_-_5894777 0.74 ENST00000324989.7
CRMP1
collapsin response mediator protein 1
chr1_-_236046872 0.74 ENST00000536965.1
LYST
lysosomal trafficking regulator
chr4_+_2626988 0.74 ENST00000509050.1
FAM193A
family with sequence similarity 193, member A
chr1_-_169555709 0.73 ENST00000546081.1
F5
coagulation factor V (proaccelerin, labile factor)
chr12_-_114843889 0.72 ENST00000405440.2
TBX5
T-box 5
chr10_-_76868931 0.70 ENST00000372700.3
ENST00000473072.2
ENST00000491677.2
ENST00000607131.1
ENST00000372702.3
DUSP13
dual specificity phosphatase 13
chr20_+_54987168 0.69 ENST00000360314.3
CASS4
Cas scaffolding protein family member 4
chr8_+_144718171 0.69 ENST00000526926.1
ENST00000458270.2
ZNF623
zinc finger protein 623
chr3_-_149688655 0.67 ENST00000461930.1
ENST00000423691.2
ENST00000490975.1
ENST00000461868.1
ENST00000452853.2
PFN2
profilin 2
chr12_-_120241187 0.66 ENST00000392520.2
CIT
citron (rho-interacting, serine/threonine kinase 21)
chr6_-_46138676 0.63 ENST00000371383.2
ENST00000230565.3
ENPP5
ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)
chr11_+_64692143 0.63 ENST00000164133.2
ENST00000532850.1
PPP2R5B
protein phosphatase 2, regulatory subunit B', beta
chr1_+_110036674 0.62 ENST00000393709.3
CYB561D1
cytochrome b561 family, member D1
chrX_-_152245978 0.62 ENST00000538162.2
PNMA6D
paraneoplastic Ma antigen family member 6D (pseudogene)
chr8_-_42623747 0.61 ENST00000534622.1
CHRNA6
cholinergic receptor, nicotinic, alpha 6 (neuronal)
chr17_+_75123947 0.61 ENST00000586429.1
SEC14L1
SEC14-like 1 (S. cerevisiae)
chr20_+_54987305 0.59 ENST00000371336.3
ENST00000434344.1
CASS4
Cas scaffolding protein family member 4
chr3_-_195163584 0.58 ENST00000439666.1
ACAP2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chrX_+_134166333 0.57 ENST00000257013.7
FAM127A
family with sequence similarity 127, member A
chr8_-_42623924 0.57 ENST00000276410.2
CHRNA6
cholinergic receptor, nicotinic, alpha 6 (neuronal)
chr10_-_76868866 0.56 ENST00000607487.1
DUSP13
dual specificity phosphatase 13
chr19_+_39926791 0.50 ENST00000594990.1
SUPT5H
suppressor of Ty 5 homolog (S. cerevisiae)
chr1_-_204463829 0.50 ENST00000429009.1
ENST00000415899.1
PIK3C2B
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
chr19_-_55549624 0.50 ENST00000417454.1
ENST00000310373.3
ENST00000333884.2
GP6
glycoprotein VI (platelet)
chr5_-_82969363 0.48 ENST00000503117.1
HAPLN1
hyaluronan and proteoglycan link protein 1
chr1_+_110036699 0.48 ENST00000496961.1
ENST00000533024.1
ENST00000310611.4
ENST00000527072.1
ENST00000420578.2
ENST00000528785.1
CYB561D1
cytochrome b561 family, member D1
chr5_-_169725231 0.45 ENST00000046794.5
LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr1_+_12040238 0.44 ENST00000444836.1
ENST00000235329.5
MFN2
mitofusin 2
chr3_-_195163803 0.43 ENST00000326793.6
ACAP2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr1_+_65210772 0.42 ENST00000371072.4
ENST00000294428.3
RAVER2
ribonucleoprotein, PTB-binding 2
chr1_-_169555779 0.42 ENST00000367797.3
ENST00000367796.3
F5
coagulation factor V (proaccelerin, labile factor)
chr10_+_99332198 0.39 ENST00000307518.5
ENST00000298808.5
ENST00000370655.1
ANKRD2
ankyrin repeat domain 2 (stretch responsive muscle)
chrX_-_152343394 0.38 ENST00000370261.1
PNMA6B
paraneoplastic Ma antigen family member 6B (pseudogene)
chr11_-_130786333 0.38 ENST00000533214.1
ENST00000528555.1
ENST00000530356.1
ENST00000539184.1
SNX19
sorting nexin 19
chr4_-_7436671 0.37 ENST00000319098.4
PSAPL1
prosaposin-like 1 (gene/pseudogene)
chr19_+_52848659 0.37 ENST00000327920.8
ZNF610
zinc finger protein 610
chr7_-_38394118 0.37 ENST00000390345.2
TRGV4
T cell receptor gamma variable 4
chr6_+_42141029 0.35 ENST00000372958.1
GUCA1A
guanylate cyclase activator 1A (retina)
chr6_+_30851205 0.33 ENST00000515881.1
DDR1
discoidin domain receptor tyrosine kinase 1
chrX_+_118708517 0.33 ENST00000346330.3
UBE2A
ubiquitin-conjugating enzyme E2A
chr9_+_74526384 0.33 ENST00000334731.2
ENST00000377031.3
C9orf85
chromosome 9 open reading frame 85
chr5_+_75379224 0.33 ENST00000322285.7
SV2C
synaptic vesicle glycoprotein 2C
chr3_-_49131614 0.32 ENST00000450685.1
QRICH1
glutamine-rich 1
chrX_+_152240819 0.31 ENST00000421798.3
ENST00000535416.1
PNMA6C
PNMA6A
paraneoplastic Ma antigen family member 6C
paraneoplastic Ma antigen family member 6A
chr5_-_74807418 0.30 ENST00000405807.4
ENST00000261415.7
COL4A3BP
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
chr2_-_25565377 0.29 ENST00000264709.3
ENST00000406659.3
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr11_-_130786400 0.27 ENST00000265909.4
SNX19
sorting nexin 19
chr2_-_154335300 0.27 ENST00000325926.3
RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chr9_+_125132803 0.27 ENST00000540753.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr20_-_62203808 0.26 ENST00000467148.1
HELZ2
helicase with zinc finger 2, transcriptional coactivator
chrX_-_118827333 0.25 ENST00000360156.7
ENST00000354228.4
ENST00000489216.1
ENST00000354416.3
ENST00000394610.1
ENST00000343984.5
SEPT6
septin 6
chr1_+_110036728 0.25 ENST00000369868.3
ENST00000430195.2
CYB561D1
cytochrome b561 family, member D1
chr7_-_127225620 0.25 ENST00000321407.2
GCC1
GRIP and coiled-coil domain containing 1
chr18_-_33709268 0.25 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
SLC39A6
solute carrier family 39 (zinc transporter), member 6
chrX_+_118708493 0.24 ENST00000371558.2
UBE2A
ubiquitin-conjugating enzyme E2A
chr4_+_159236462 0.23 ENST00000460056.2
RXFP1
relaxin/insulin-like family peptide receptor 1
chr5_+_74807886 0.21 ENST00000514296.1
POLK
polymerase (DNA directed) kappa
chr3_-_49131788 0.19 ENST00000395443.2
ENST00000411682.1
QRICH1
glutamine-rich 1
chrX_+_152338301 0.18 ENST00000453825.2
PNMA6A
paraneoplastic Ma antigen family member 6A
chr5_+_140514782 0.16 ENST00000231134.5
PCDHB5
protocadherin beta 5
chr2_-_136594740 0.16 ENST00000264162.2
LCT
lactase
chr1_-_32801825 0.14 ENST00000329421.7
MARCKSL1
MARCKS-like 1
chr9_+_74526532 0.14 ENST00000486911.2
C9orf85
chromosome 9 open reading frame 85
chr17_+_33895090 0.13 ENST00000592381.1
RP11-1094M14.11
RP11-1094M14.11
chr1_-_149908710 0.11 ENST00000439741.2
ENST00000361405.6
ENST00000406732.3
MTMR11
myotubularin related protein 11
chr4_+_48492269 0.10 ENST00000327939.4
ZAR1
zygote arrest 1
chr12_+_8185288 0.10 ENST00000162391.3
FOXJ2
forkhead box J2
chr16_+_89787393 0.10 ENST00000289816.5
ENST00000568064.1
ZNF276
zinc finger protein 276
chr3_-_49131473 0.09 ENST00000430979.1
ENST00000357496.2
ENST00000437939.1
QRICH1
glutamine-rich 1
chr2_+_241631262 0.09 ENST00000337801.4
ENST00000429564.1
AQP12A
aquaporin 12A
chr15_-_74659978 0.07 ENST00000541301.1
ENST00000416978.1
ENST00000268053.6
CYP11A1
cytochrome P450, family 11, subfamily A, polypeptide 1
chr7_+_23719749 0.06 ENST00000409192.3
ENST00000344962.4
ENST00000409653.1
ENST00000409994.3
FAM221A
family with sequence similarity 221, member A
chr12_+_123949053 0.06 ENST00000350887.5
SNRNP35
small nuclear ribonucleoprotein 35kDa (U11/U12)
chr8_+_42196000 0.04 ENST00000518925.1
ENST00000538005.1
POLB
polymerase (DNA directed), beta
chr3_+_178276488 0.02 ENST00000432997.1
ENST00000455865.1
KCNMB2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr1_+_210001309 0.01 ENST00000491415.2
DIEXF
digestive organ expansion factor homolog (zebrafish)
chrX_+_11776278 0.01 ENST00000312196.4
ENST00000337339.2
MSL3
male-specific lethal 3 homolog (Drosophila)

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.6 3.7 GO:0021633 optic nerve structural organization(GO:0021633)
0.6 1.8 GO:0072720 cellular response to mycotoxin(GO:0036146) response to dithiothreitol(GO:0072720)
0.4 2.0 GO:0060024 rhythmic synaptic transmission(GO:0060024) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.3 4.3 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.3 1.1 GO:0006781 succinyl-CoA pathway(GO:0006781)
0.2 0.7 GO:1904530 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.2 0.7 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.2 0.7 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.2 1.1 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
0.2 1.8 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.2 2.4 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.2 3.9 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.2 1.2 GO:0032571 response to vitamin K(GO:0032571)
0.2 2.3 GO:2001015 negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.2 0.7 GO:1990502 dense core granule maturation(GO:1990502)
0.2 4.5 GO:0060134 prepulse inhibition(GO:0060134)
0.1 1.3 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.1 1.4 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.1 2.3 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.1 0.3 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.1 2.4 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.1 1.1 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 2.3 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 0.6 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.1 4.0 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 0.9 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.9 GO:0099612 protein localization to axon(GO:0099612)
0.0 2.9 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.6 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 1.8 GO:0035640 exploration behavior(GO:0035640)
0.0 0.3 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 1.0 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.0 1.0 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.4 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.0 1.8 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.3 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.5 GO:0032785 negative regulation of DNA-templated transcription, elongation(GO:0032785)
0.0 0.2 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.4 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 0.4 GO:0060742 epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.0 2.9 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 5.0 GO:0030168 platelet activation(GO:0030168)
0.0 3.7 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 1.1 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.0 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 0.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 2.3 GO:0007030 Golgi organization(GO:0007030)
0.0 0.6 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.0 0.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.5 GO:0072678 T cell migration(GO:0072678)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.7 GO:0033010 paranodal junction(GO:0033010)
0.2 3.6 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.2 1.1 GO:0014802 terminal cisterna(GO:0014802)
0.2 0.9 GO:1990769 proximal neuron projection(GO:1990769)
0.1 0.5 GO:0036398 TCR signalosome(GO:0036398)
0.1 4.1 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 0.3 GO:0005940 septin ring(GO:0005940) septin collar(GO:0032173)
0.1 0.5 GO:0032044 DSIF complex(GO:0032044)
0.1 1.3 GO:1990909 Wnt signalosome(GO:1990909)
0.1 0.9 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.6 GO:0033503 HULC complex(GO:0033503)
0.0 1.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 1.0 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 2.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.5 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 4.3 GO:0043195 terminal bouton(GO:0043195)
0.0 2.4 GO:0043198 dendritic shaft(GO:0043198)
0.0 5.3 GO:0031091 platelet alpha granule(GO:0031091)
0.0 1.6 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 2.3 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.7 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.3 GO:0001741 XY body(GO:0001741)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 0.4 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0 2.8 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.2 GO:0031258 lamellipodium membrane(GO:0031258)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.1 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
0.3 2.4 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.3 3.9 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.2 1.1 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.2 3.7 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 0.4 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 1.8 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 0.6 GO:0039552 RIG-I binding(GO:0039552)
0.1 2.3 GO:0050786 tau protein binding(GO:0048156) RAGE receptor binding(GO:0050786)
0.1 1.8 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 2.1 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 2.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 3.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.9 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 4.3 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.8 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 1.8 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.1 1.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.3 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 1.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 0.3 GO:0097001 ceramide binding(GO:0097001)
0.0 0.3 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 1.2 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.5 GO:0035005 lipid kinase activity(GO:0001727) 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 1.0 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 1.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 4.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 2.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 2.9 GO:1901476 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.0 0.2 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.7 GO:0031005 filamin binding(GO:0031005)
0.0 1.0 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.0 1.8 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 2.4 GO:0030295 protein kinase activator activity(GO:0030295)
0.0 1.3 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 1.2 GO:0005507 copper ion binding(GO:0005507)
0.0 2.0 GO:0030165 PDZ domain binding(GO:0030165)
0.0 1.1 GO:0043022 ribosome binding(GO:0043022)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 2.3 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 3.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.3 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.8 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.0 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.3 PID CONE PATHWAY Visual signal transduction: Cones

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 2.3 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 1.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 2.4 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 1.9 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 4.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 1.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 4.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 3.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.8 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.1 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 2.3 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.7 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 1.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.5 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 0.7 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.9 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism