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Illumina Body Map 2: averaged replicates

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Results for ZIC2_GLI1

Z-value: 1.76

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Transcription factors associated with ZIC2_GLI1

Gene Symbol Gene ID Gene Info
ZIC2
ENSG00000043355.6 Zic family member 2
GLI1
ENSG00000111087.5 GLI family zinc finger 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GLI1hg19_v2_chr12_+_57854274_578542740.291.0e-01Click!
ZIC2hg19_v2_chr13_+_100634004_1006340260.232.1e-01Click!

Activity profile of ZIC2_GLI1 motif

Sorted Z-values of ZIC2_GLI1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_111783919 8.37 ENST00000531198.1
ENST00000533879.1
CRYAB
crystallin, alpha B
chr1_+_47264711 7.89 ENST00000371923.4
ENST00000271153.4
ENST00000371919.4
CYP4B1
cytochrome P450, family 4, subfamily B, polypeptide 1
chr11_-_111783595 7.46 ENST00000528628.1
CRYAB
crystallin, alpha B
chr11_+_111783450 6.86 ENST00000537382.1
HSPB2
Homo sapiens heat shock 27kDa protein 2 (HSPB2), mRNA.
chr5_-_168727713 6.62 ENST00000404867.3
SLIT3
slit homolog 3 (Drosophila)
chr11_+_111782934 6.58 ENST00000304298.3
HSPB2
Homo sapiens heat shock 27kDa protein 2 (HSPB2), mRNA.
chr5_-_168727786 6.30 ENST00000332966.8
SLIT3
slit homolog 3 (Drosophila)
chr5_-_44388899 6.29 ENST00000264664.4
FGF10
fibroblast growth factor 10
chr20_+_36149602 5.94 ENST00000062104.2
ENST00000346199.2
NNAT
neuronatin
chr3_-_73673991 4.89 ENST00000308537.4
ENST00000263666.4
PDZRN3
PDZ domain containing ring finger 3
chrX_+_90689810 4.68 ENST00000312600.3
PABPC5
poly(A) binding protein, cytoplasmic 5
chr1_-_40105617 4.30 ENST00000372852.3
HEYL
hes-related family bHLH transcription factor with YRPW motif-like
chr8_-_17555164 4.13 ENST00000297488.6
MTUS1
microtubule associated tumor suppressor 1
chr20_+_43343476 3.60 ENST00000372868.2
WISP2
WNT1 inducible signaling pathway protein 2
chr3_+_153839149 3.52 ENST00000465093.1
ENST00000465817.1
ARHGEF26
Rho guanine nucleotide exchange factor (GEF) 26
chr9_-_124989804 3.44 ENST00000373755.2
ENST00000373754.2
LHX6
LIM homeobox 6
chr10_-_95360983 3.40 ENST00000371464.3
RBP4
retinol binding protein 4, plasma
chr20_+_43343886 3.31 ENST00000190983.4
WISP2
WNT1 inducible signaling pathway protein 2
chr2_+_137523086 3.26 ENST00000409968.1
THSD7B
thrombospondin, type I, domain containing 7B
chr21_-_27945562 3.22 ENST00000299340.4
ENST00000435845.2
CYYR1
cysteine/tyrosine-rich 1
chr6_-_26027480 3.22 ENST00000377364.3
HIST1H4B
histone cluster 1, H4b
chr17_-_74533734 3.21 ENST00000589342.1
CYGB
cytoglobin
chr14_+_101292445 3.20 ENST00000429159.2
ENST00000520714.1
ENST00000522771.2
ENST00000424076.3
ENST00000423456.1
ENST00000521404.1
ENST00000556736.1
ENST00000451743.2
ENST00000398518.2
ENST00000554639.1
ENST00000452120.2
ENST00000519709.1
ENST00000412736.2
MEG3
maternally expressed 3 (non-protein coding)
chr1_-_45308616 3.17 ENST00000447098.2
ENST00000372192.3
PTCH2
patched 2
chr7_+_119913688 3.08 ENST00000331113.4
KCND2
potassium voltage-gated channel, Shal-related subfamily, member 2
chr5_+_71403061 3.05 ENST00000512974.1
ENST00000296755.7
MAP1B
microtubule-associated protein 1B
chr4_-_5021164 3.05 ENST00000506508.1
ENST00000509419.1
ENST00000307746.4
CYTL1
cytokine-like 1
chr1_-_171621815 3.03 ENST00000037502.6
MYOC
myocilin, trabecular meshwork inducible glucocorticoid response
chr19_+_676385 3.00 ENST00000166139.4
FSTL3
follistatin-like 3 (secreted glycoprotein)
chr17_+_6926339 2.93 ENST00000293805.5
BCL6B
B-cell CLL/lymphoma 6, member B
chr11_+_118478313 2.92 ENST00000356063.5
PHLDB1
pleckstrin homology-like domain, family B, member 1
chr8_+_75736761 2.86 ENST00000260113.2
PI15
peptidase inhibitor 15
chr8_+_30244580 2.70 ENST00000523115.1
ENST00000519647.1
RBPMS
RNA binding protein with multiple splicing
chr15_-_93616892 2.62 ENST00000556658.1
ENST00000538818.1
ENST00000425933.2
RGMA
repulsive guidance molecule family member a
chr20_+_43343517 2.54 ENST00000372865.4
WISP2
WNT1 inducible signaling pathway protein 2
chr5_-_141704566 2.48 ENST00000344120.4
ENST00000434127.2
SPRY4
sprouty homolog 4 (Drosophila)
chr5_+_71403280 2.47 ENST00000511641.2
MAP1B
microtubule-associated protein 1B
chr11_+_76493294 2.39 ENST00000533752.1
TSKU
tsukushi, small leucine rich proteoglycan
chr11_-_111784005 2.37 ENST00000527899.1
CRYAB
crystallin, alpha B
chr21_-_28215332 2.35 ENST00000517777.1
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr16_+_86612112 2.35 ENST00000320241.3
FOXL1
forkhead box L1
chr19_-_35625765 2.35 ENST00000591633.1
LGI4
leucine-rich repeat LGI family, member 4
chr2_+_217498105 2.31 ENST00000233809.4
IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr6_+_163148973 2.26 ENST00000366888.2
PACRG
PARK2 co-regulated
chr11_-_12030681 2.17 ENST00000529338.1
DKK3
dickkopf WNT signaling pathway inhibitor 3
chr5_+_52776449 2.14 ENST00000396947.3
FST
follistatin
chr17_+_6926381 2.14 ENST00000576705.1
BCL6B
B-cell CLL/lymphoma 6, member B
chr9_+_109625378 2.13 ENST00000277225.5
ENST00000457913.1
ENST00000472574.1
ZNF462
zinc finger protein 462
chr17_-_74533963 2.07 ENST00000293230.5
CYGB
cytoglobin
chr11_-_111782696 2.04 ENST00000227251.3
ENST00000526180.1
CRYAB
crystallin, alpha B
chr4_-_186696425 2.03 ENST00000430503.1
ENST00000319454.6
ENST00000450341.1
SORBS2
sorbin and SH3 domain containing 2
chr7_+_116312411 2.02 ENST00000456159.1
ENST00000397752.3
ENST00000318493.6
MET
met proto-oncogene
chr11_-_75379612 2.02 ENST00000526740.1
MAP6
microtubule-associated protein 6
chr4_-_187517928 1.99 ENST00000512772.1
FAT1
FAT atypical cadherin 1
chr11_-_111782484 1.99 ENST00000533971.1
CRYAB
crystallin, alpha B
chr6_+_43739697 1.98 ENST00000230480.6
VEGFA
vascular endothelial growth factor A
chr5_+_52776228 1.98 ENST00000256759.3
FST
follistatin
chr19_+_45312347 1.97 ENST00000270233.6
ENST00000591520.1
BCAM
basal cell adhesion molecule (Lutheran blood group)
chr9_-_34397800 1.94 ENST00000297623.2
C9orf24
chromosome 9 open reading frame 24
chr11_-_11643540 1.92 ENST00000227756.4
GALNT18
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 18
chr11_-_12030130 1.81 ENST00000450094.2
ENST00000534511.1
DKK3
dickkopf WNT signaling pathway inhibitor 3
chr19_+_45312310 1.78 ENST00000589651.1
BCAM
basal cell adhesion molecule (Lutheran blood group)
chr6_-_29600559 1.76 ENST00000476670.1
GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr7_+_130131907 1.70 ENST00000223215.4
ENST00000437945.1
MEST
mesoderm specific transcript
chr19_-_51456321 1.69 ENST00000391809.2
KLK5
kallikrein-related peptidase 5
chr11_-_12030629 1.68 ENST00000396505.2
DKK3
dickkopf WNT signaling pathway inhibitor 3
chr6_+_17281802 1.67 ENST00000509686.1
RBM24
RNA binding motif protein 24
chr17_+_7608511 1.65 ENST00000226091.2
EFNB3
ephrin-B3
chr11_-_75379479 1.64 ENST00000434603.2
MAP6
microtubule-associated protein 6
chr17_+_40834580 1.63 ENST00000264638.4
CNTNAP1
contactin associated protein 1
chr17_-_34122596 1.61 ENST00000250144.8
MMP28
matrix metallopeptidase 28
chr9_+_131174024 1.59 ENST00000420034.1
ENST00000372842.1
CERCAM
cerebral endothelial cell adhesion molecule
chr16_+_28875268 1.57 ENST00000395532.4
SH2B1
SH2B adaptor protein 1
chr21_-_27945464 1.57 ENST00000400043.3
CYYR1
cysteine/tyrosine-rich 1
chr7_-_151107106 1.54 ENST00000334493.6
WDR86
WD repeat domain 86
chr4_-_186696561 1.53 ENST00000445115.1
ENST00000451701.1
ENST00000457247.1
ENST00000435480.1
ENST00000425679.1
ENST00000457934.1
SORBS2
sorbin and SH3 domain containing 2
chr17_+_76422409 1.53 ENST00000600087.1
AC061992.1
Uncharacterized protein
chr3_+_159481464 1.51 ENST00000467377.1
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr21_-_28217721 1.51 ENST00000284984.3
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr11_-_64527425 1.49 ENST00000377432.3
PYGM
phosphorylase, glycogen, muscle
chr4_-_186697044 1.49 ENST00000437304.2
SORBS2
sorbin and SH3 domain containing 2
chr14_-_30396802 1.48 ENST00000415220.2
PRKD1
protein kinase D1
chr1_+_164528866 1.46 ENST00000420696.2
PBX1
pre-B-cell leukemia homeobox 1
chr19_-_51456344 1.46 ENST00000336334.3
ENST00000593428.1
KLK5
kallikrein-related peptidase 5
chr10_+_24755416 1.44 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
KIAA1217
chr1_-_183387723 1.44 ENST00000287713.6
NMNAT2
nicotinamide nucleotide adenylyltransferase 2
chr19_-_41196534 1.41 ENST00000252891.4
NUMBL
numb homolog (Drosophila)-like
chr20_+_62327996 1.41 ENST00000369996.1
TNFRSF6B
tumor necrosis factor receptor superfamily, member 6b, decoy
chr19_-_40919271 1.40 ENST00000291825.7
ENST00000324001.7
PRX
periaxin
chr19_-_41196458 1.38 ENST00000598779.1
NUMBL
numb homolog (Drosophila)-like
chr1_-_182573514 1.37 ENST00000367558.5
RGS16
regulator of G-protein signaling 16
chr16_+_86600857 1.37 ENST00000320354.4
FOXC2
forkhead box C2 (MFH-1, mesenchyme forkhead 1)
chr10_-_90712520 1.37 ENST00000224784.6
ACTA2
actin, alpha 2, smooth muscle, aorta
chr14_-_23834411 1.35 ENST00000429593.2
EFS
embryonal Fyn-associated substrate
chr1_+_226736446 1.33 ENST00000366788.3
ENST00000366789.4
C1orf95
chromosome 1 open reading frame 95
chr3_+_159481791 1.31 ENST00000460298.1
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr5_-_148758839 1.30 ENST00000261796.3
IL17B
interleukin 17B
chr9_+_135285579 1.28 ENST00000343036.2
ENST00000393216.2
C9orf171
chromosome 9 open reading frame 171
chr11_-_65640071 1.25 ENST00000526624.1
EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr2_-_133427767 1.25 ENST00000397463.2
LYPD1
LY6/PLAUR domain containing 1
chr5_-_137878887 1.23 ENST00000507939.1
ENST00000572514.1
ENST00000499810.2
ENST00000360541.5
ETF1
eukaryotic translation termination factor 1
chr2_-_213403565 1.22 ENST00000342788.4
ENST00000436443.1
ERBB4
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
chr4_+_62067860 1.21 ENST00000514591.1
LPHN3
latrophilin 3
chr11_-_119991589 1.20 ENST00000526881.1
TRIM29
tripartite motif containing 29
chr6_+_125540951 1.20 ENST00000524679.1
TPD52L1
tumor protein D52-like 1
chr3_+_170136642 1.18 ENST00000064724.3
ENST00000486975.1
CLDN11
claudin 11
chr17_+_17876127 1.18 ENST00000582416.1
ENST00000313838.8
ENST00000411504.2
ENST00000581264.1
ENST00000399187.1
ENST00000479684.2
ENST00000584166.1
ENST00000585108.1
ENST00000399182.1
ENST00000579977.1
LRRC48
leucine rich repeat containing 48
chr5_-_137090028 1.18 ENST00000314940.4
HNRNPA0
heterogeneous nuclear ribonucleoprotein A0
chr18_+_21529811 1.17 ENST00000588004.1
LAMA3
laminin, alpha 3
chr2_+_159825143 1.15 ENST00000454300.1
ENST00000263635.6
TANC1
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chr2_+_26915584 1.15 ENST00000302909.3
KCNK3
potassium channel, subfamily K, member 3
chr2_-_193059634 1.15 ENST00000392314.1
TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr4_-_186696636 1.14 ENST00000444771.1
SORBS2
sorbin and SH3 domain containing 2
chr13_+_44947941 1.14 ENST00000379179.3
SERP2
stress-associated endoplasmic reticulum protein family member 2
chr3_+_159481988 1.13 ENST00000472451.1
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chrX_+_70364667 1.13 ENST00000536169.1
ENST00000395855.2
ENST00000374051.3
ENST00000358741.3
NLGN3
neuroligin 3
chr16_+_86229728 1.12 ENST00000601250.1
LINC01082
long intergenic non-protein coding RNA 1082
chr4_-_186696515 1.09 ENST00000456596.1
ENST00000414724.1
SORBS2
sorbin and SH3 domain containing 2
chr14_-_61124977 1.09 ENST00000554986.1
SIX1
SIX homeobox 1
chr6_-_29600832 1.09 ENST00000377016.4
ENST00000376977.3
ENST00000377034.4
GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr22_-_28197486 1.08 ENST00000302326.4
MN1
meningioma (disrupted in balanced translocation) 1
chr4_+_134070439 1.06 ENST00000264360.5
PCDH10
protocadherin 10
chr1_-_38512450 1.06 ENST00000373012.2
POU3F1
POU class 3 homeobox 1
chr11_-_30608413 1.04 ENST00000528686.1
MPPED2
metallophosphoesterase domain containing 2
chr11_+_45168182 1.04 ENST00000526442.1
PRDM11
PR domain containing 11
chr7_-_108096765 0.98 ENST00000379024.4
ENST00000351718.4
NRCAM
neuronal cell adhesion molecule
chr2_+_25016282 0.96 ENST00000260662.1
CENPO
centromere protein O
chr13_-_30880979 0.96 ENST00000414289.1
KATNAL1
katanin p60 subunit A-like 1
chr3_+_113616317 0.95 ENST00000440446.2
ENST00000488680.1
GRAMD1C
GRAM domain containing 1C
chr7_-_108096822 0.95 ENST00000379028.3
ENST00000413765.2
ENST00000379022.4
NRCAM
neuronal cell adhesion molecule
chr1_-_205782304 0.95 ENST00000367137.3
SLC41A1
solute carrier family 41 (magnesium transporter), member 1
chr10_-_97050777 0.94 ENST00000329399.6
PDLIM1
PDZ and LIM domain 1
chr6_-_19804973 0.94 ENST00000457670.1
ENST00000607810.1
ENST00000606628.1
RP4-625H18.2
RP4-625H18.2
chrX_-_138287168 0.93 ENST00000436198.1
FGF13
fibroblast growth factor 13
chr10_-_35104185 0.90 ENST00000374789.3
ENST00000374788.3
ENST00000346874.4
ENST00000374794.3
ENST00000350537.4
ENST00000374790.3
ENST00000374776.1
ENST00000374773.1
ENST00000545693.1
ENST00000545260.1
ENST00000340077.5
PARD3
par-3 family cell polarity regulator
chr16_-_21452040 0.88 ENST00000521589.1
NPIPB3
nuclear pore complex interacting protein family, member B3
chr10_-_69455873 0.88 ENST00000433211.2
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr2_+_25015968 0.87 ENST00000380834.2
ENST00000473706.1
CENPO
centromere protein O
chr17_-_7137582 0.87 ENST00000575756.1
ENST00000575458.1
DVL2
dishevelled segment polarity protein 2
chr17_-_7137857 0.86 ENST00000005340.5
DVL2
dishevelled segment polarity protein 2
chr9_-_98079154 0.85 ENST00000433829.1
FANCC
Fanconi anemia, complementation group C
chr15_-_23891175 0.83 ENST00000532292.1
MAGEL2
MAGE-like 2
chr14_-_51561784 0.82 ENST00000360392.4
TRIM9
tripartite motif containing 9
chrX_-_140271249 0.81 ENST00000370526.2
LDOC1
leucine zipper, down-regulated in cancer 1
chr2_-_51259641 0.78 ENST00000406316.2
ENST00000405581.1
NRXN1
neurexin 1
chr9_+_136399929 0.78 ENST00000393060.1
ADAMTSL2
ADAMTS-like 2
chr1_+_42846443 0.77 ENST00000410070.2
ENST00000431473.3
RIMKLA
ribosomal modification protein rimK-like family member A
chr20_+_32782375 0.76 ENST00000568305.1
ASIP
agouti signaling protein
chr19_-_42758040 0.76 ENST00000593944.1
ERF
Ets2 repressor factor
chr2_-_28113965 0.76 ENST00000302188.3
RBKS
ribokinase
chr16_-_85146040 0.75 ENST00000539556.1
FAM92B
family with sequence similarity 92, member B
chr6_-_110500826 0.75 ENST00000265601.3
ENST00000447287.1
ENST00000444391.1
WASF1
WAS protein family, member 1
chr17_-_15496722 0.73 ENST00000472534.1
CDRT1
CMT1A duplicated region transcript 1
chr6_-_55739542 0.73 ENST00000446683.2
BMP5
bone morphogenetic protein 5
chr1_+_183155373 0.72 ENST00000493293.1
ENST00000264144.4
LAMC2
laminin, gamma 2
chr7_-_33842742 0.71 ENST00000420185.1
ENST00000440034.1
RP11-89N17.4
RP11-89N17.4
chr3_+_110790867 0.70 ENST00000486596.1
ENST00000493615.1
PVRL3
poliovirus receptor-related 3
chr8_-_41522719 0.67 ENST00000335651.6
ANK1
ankyrin 1, erythrocytic
chr2_-_51259528 0.67 ENST00000404971.1
NRXN1
neurexin 1
chr9_-_130639997 0.65 ENST00000373176.1
AK1
adenylate kinase 1
chr9_+_135285430 0.65 ENST00000393215.3
C9orf171
chromosome 9 open reading frame 171
chrX_-_107979616 0.65 ENST00000372129.2
IRS4
insulin receptor substrate 4
chr10_-_77161004 0.65 ENST00000418818.2
RP11-399K21.11
RP11-399K21.11
chr7_-_108097144 0.64 ENST00000418239.1
NRCAM
neuronal cell adhesion molecule
chr2_-_213403253 0.64 ENST00000260943.6
ENST00000402597.1
ERBB4
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
chr4_-_134070250 0.64 ENST00000505289.1
ENST00000509715.1
RP11-9G1.3
RP11-9G1.3
chr17_-_15244894 0.64 ENST00000338696.2
ENST00000543896.1
ENST00000539245.1
ENST00000539316.1
ENST00000395930.1
TEKT3
tektin 3
chr15_-_77712429 0.63 ENST00000564328.1
ENST00000558305.1
PEAK1
pseudopodium-enriched atypical kinase 1
chr3_+_137717571 0.63 ENST00000343735.4
CLDN18
claudin 18
chr9_-_33264557 0.63 ENST00000473781.1
ENST00000488499.1
BAG1
BCL2-associated athanogene
chr11_+_59224411 0.63 ENST00000300127.2
OR4D6
olfactory receptor, family 4, subfamily D, member 6
chr6_+_43968306 0.63 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
C6orf223
chromosome 6 open reading frame 223
chr1_-_217250231 0.62 ENST00000493748.1
ENST00000463665.1
ESRRG
estrogen-related receptor gamma
chr14_+_96968802 0.61 ENST00000556619.1
ENST00000392990.2
PAPOLA
poly(A) polymerase alpha
chr3_+_6902794 0.60 ENST00000357716.4
ENST00000486284.1
ENST00000389336.4
ENST00000403881.1
ENST00000402647.2
GRM7
glutamate receptor, metabotropic 7
chr2_+_68694678 0.59 ENST00000303795.4
APLF
aprataxin and PNKP like factor
chr3_+_110790715 0.58 ENST00000319792.3
PVRL3
poliovirus receptor-related 3
chr1_+_32674675 0.56 ENST00000409358.1
DCDC2B
doublecortin domain containing 2B
chr10_-_77161650 0.56 ENST00000372524.4
ZNF503
zinc finger protein 503
chr10_-_77161533 0.54 ENST00000535216.1
ZNF503
zinc finger protein 503
chr9_+_34990219 0.54 ENST00000541010.1
ENST00000454002.2
ENST00000545841.1
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr22_+_38201114 0.54 ENST00000340857.2
H1F0
H1 histone family, member 0
chr17_-_17875688 0.54 ENST00000379504.3
ENST00000318094.10
ENST00000540946.1
ENST00000542206.1
ENST00000395739.4
ENST00000581396.1
ENST00000535933.1
ENST00000579586.1
TOM1L2
target of myb1-like 2 (chicken)
chr3_+_110790590 0.54 ENST00000485303.1
PVRL3
poliovirus receptor-related 3
chr2_-_51259292 0.53 ENST00000401669.2
NRXN1
neurexin 1
chr16_+_57844549 0.53 ENST00000564282.1
CTD-2600O9.1
uncharacterized protein LOC388282
chr11_-_65321198 0.53 ENST00000530426.1
LTBP3
latent transforming growth factor beta binding protein 3
chr12_+_65996599 0.53 ENST00000539116.1
ENST00000541391.1
RP11-221N13.3
RP11-221N13.3
chr7_-_4901625 0.52 ENST00000404991.1
PAPOLB
poly(A) polymerase beta (testis specific)
chr22_-_46373004 0.51 ENST00000339464.4
WNT7B
wingless-type MMTV integration site family, member 7B
chr1_+_152943122 0.51 ENST00000328051.2
SPRR4
small proline-rich protein 4
chr10_-_81203972 0.51 ENST00000372333.3
ZCCHC24
zinc finger, CCHC domain containing 24
chr22_-_19165917 0.51 ENST00000451283.1
SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr22_-_30783075 0.50 ENST00000215798.6
RNF215
ring finger protein 215
chr22_-_19166343 0.50 ENST00000215882.5
SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr7_-_112726393 0.50 ENST00000449591.1
ENST00000449735.1
ENST00000438062.1
ENST00000424100.1
GPR85
G protein-coupled receptor 85
chrX_+_51636629 0.49 ENST00000375722.1
ENST00000326587.7
ENST00000375695.2
MAGED1
melanoma antigen family D, 1
chr10_-_18948156 0.49 ENST00000414939.1
ENST00000449529.1
ENST00000456217.1
ENST00000444660.1
ARL5B-AS1
ARL5B antisense RNA 1
chr19_-_30199516 0.49 ENST00000591243.1
C19orf12
chromosome 19 open reading frame 12
chr8_-_41522779 0.47 ENST00000522231.1
ENST00000314214.8
ENST00000348036.4
ENST00000457297.1
ENST00000522543.1
ANK1
ankyrin 1, erythrocytic

Network of associatons between targets according to the STRING database.

First level regulatory network of ZIC2_GLI1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 12.9 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
2.1 6.3 GO:0071335 proximal/distal axis specification(GO:0009946) bronchiole development(GO:0060435) submandibular salivary gland formation(GO:0060661) secretion by lung epithelial cell involved in lung growth(GO:0061033) hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
1.4 4.3 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.9 22.2 GO:0007021 tubulin complex assembly(GO:0007021)
0.9 7.9 GO:0018879 biphenyl metabolic process(GO:0018879)
0.8 3.0 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.8 5.3 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.7 5.7 GO:1990262 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.7 2.8 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.7 3.4 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.7 2.0 GO:1903572 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.6 1.9 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.6 2.4 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.5 3.1 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.5 7.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.5 5.5 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.5 1.4 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) glomerular endothelium development(GO:0072011) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.5 5.9 GO:0009249 protein lipoylation(GO:0009249)
0.4 1.7 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.4 1.1 GO:0045720 negative regulation of integrin biosynthetic process(GO:0045720)
0.4 0.7 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.3 2.4 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.3 1.0 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
0.3 1.1 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.3 2.4 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.3 1.6 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.3 4.2 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.3 0.5 GO:0072061 inner medullary collecting duct development(GO:0072061)
0.2 1.5 GO:1901727 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033) protein kinase D signaling(GO:0089700) positive regulation of histone deacetylase activity(GO:1901727)
0.2 3.4 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.2 1.4 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.2 1.4 GO:0090131 mesenchyme migration(GO:0090131)
0.2 1.1 GO:0060024 rhythmic synaptic transmission(GO:0060024) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.2 5.5 GO:0061339 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.2 0.8 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.2 3.9 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.2 3.0 GO:0045475 locomotor rhythm(GO:0045475)
0.2 0.9 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.2 0.8 GO:0019303 D-ribose catabolic process(GO:0019303)
0.1 7.3 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 1.6 GO:0016198 axon choice point recognition(GO:0016198)
0.1 1.0 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.1 0.4 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.1 1.3 GO:0051013 microtubule severing(GO:0051013)
0.1 0.3 GO:0010748 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.1 0.6 GO:0080154 regulation of fertilization(GO:0080154)
0.1 1.7 GO:0009957 epidermal cell fate specification(GO:0009957)
0.1 4.3 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.1 2.8 GO:0070831 basement membrane assembly(GO:0070831)
0.1 0.8 GO:0060482 lobar bronchus development(GO:0060482)
0.1 1.1 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.1 2.6 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.1 1.1 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.4 GO:0048859 formation of anatomical boundary(GO:0048859)
0.1 2.7 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.1 0.9 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.1 0.5 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.1 0.6 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.1 2.4 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 0.4 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.1 1.1 GO:0006449 regulation of translational termination(GO:0006449)
0.1 0.9 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1 0.8 GO:0008343 adult feeding behavior(GO:0008343)
0.1 1.3 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.1 0.4 GO:0060179 male mating behavior(GO:0060179)
0.1 3.1 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.1 0.7 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 4.9 GO:0007528 neuromuscular junction development(GO:0007528)
0.1 0.8 GO:0060137 maternal process involved in parturition(GO:0060137)
0.1 0.6 GO:0051106 positive regulation of DNA ligation(GO:0051106)
0.1 3.0 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.1 0.3 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.1 0.5 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1 0.1 GO:0006109 regulation of carbohydrate metabolic process(GO:0006109)
0.0 1.1 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0 0.5 GO:0042711 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.0 0.7 GO:0045023 G0 to G1 transition(GO:0045023)
0.0 1.1 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.3 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.3 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 1.8 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.2 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 1.2 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 1.5 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 12.7 GO:0006986 response to unfolded protein(GO:0006986)
0.0 1.2 GO:1905145 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 0.3 GO:0071313 cellular response to caffeine(GO:0071313)
0.0 0.6 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 2.4 GO:0042092 type 2 immune response(GO:0042092)
0.0 1.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.6 GO:1904903 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 1.1 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 0.8 GO:0051127 positive regulation of actin nucleation(GO:0051127)
0.0 0.4 GO:0003096 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.0 1.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 1.5 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.9 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.0 0.2 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.5 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.3 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.5 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.5 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.3 GO:0007568 aging(GO:0007568)
0.0 2.1 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 1.6 GO:0045840 positive regulation of mitotic nuclear division(GO:0045840)
0.0 0.4 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 1.6 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 1.7 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.0 0.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 3.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.1 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 0.2 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.1 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.2 GO:0015684 ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
0.0 0.0 GO:0019046 release from viral latency(GO:0019046)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 22.2 GO:0097512 cardiac myofibril(GO:0097512)
0.8 3.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.4 3.1 GO:0097209 epidermal lamellar body(GO:0097209)
0.2 1.4 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.2 0.7 GO:0005607 laminin-2 complex(GO:0005607)
0.1 3.0 GO:0033268 node of Ranvier(GO:0033268)
0.1 0.6 GO:0032279 asymmetric synapse(GO:0032279)
0.1 2.1 GO:0045180 basal cortex(GO:0045180)
0.1 1.2 GO:0005610 laminin-5 complex(GO:0005610)
0.1 1.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 2.3 GO:0097225 sperm midpiece(GO:0097225)
0.1 1.6 GO:0033010 paranodal junction(GO:0033010)
0.1 2.6 GO:0043194 axon initial segment(GO:0043194)
0.1 2.7 GO:0005685 U1 snRNP(GO:0005685)
0.1 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.9 GO:0033269 internode region of axon(GO:0033269)
0.1 3.0 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 4.8 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.5 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.7 GO:0031209 SCAR complex(GO:0031209)
0.0 0.9 GO:0005916 fascia adherens(GO:0005916)
0.0 3.2 GO:0045178 basal part of cell(GO:0045178)
0.0 4.5 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.1 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 1.5 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.8 GO:0030904 retromer complex(GO:0030904)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 1.7 GO:0016235 aggresome(GO:0016235)
0.0 4.9 GO:0030018 Z disc(GO:0030018)
0.0 49.8 GO:0005615 extracellular space(GO:0005615)
0.0 1.4 GO:0005604 basement membrane(GO:0005604)
0.0 0.6 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.9 GO:0014704 intercalated disc(GO:0014704)
0.0 2.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 2.1 GO:0042734 presynaptic membrane(GO:0042734)
0.0 3.1 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.1 GO:0043679 axon terminus(GO:0043679)
0.0 3.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 2.4 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.2 GO:0030175 filopodium(GO:0030175)
0.0 0.4 GO:0031093 platelet alpha granule lumen(GO:0031093)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.3 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
1.3 5.3 GO:0047888 fatty acid peroxidase activity(GO:0047888)
1.3 12.9 GO:0048495 Roundabout binding(GO:0048495)
1.3 3.8 GO:0005055 laminin receptor activity(GO:0005055)
1.1 4.3 GO:0035939 microsatellite binding(GO:0035939)
0.7 22.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.6 3.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.4 2.7 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.4 1.5 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.4 2.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.4 3.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.3 8.4 GO:0015643 toxic substance binding(GO:0015643)
0.3 7.1 GO:0048185 activin binding(GO:0048185)
0.3 1.2 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.3 11.8 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.2 1.7 GO:0005119 smoothened binding(GO:0005119)
0.2 1.4 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.2 3.0 GO:0032027 myosin light chain binding(GO:0032027)
0.2 0.8 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590)
0.2 1.0 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.2 7.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 1.2 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 2.6 GO:1990459 transferrin receptor binding(GO:1990459)
0.1 2.4 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 1.6 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 3.4 GO:0019841 retinol binding(GO:0019841)
0.1 0.8 GO:0050436 microfibril binding(GO:0050436)
0.1 3.5 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 1.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 1.9 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 0.6 GO:0070905 serine binding(GO:0070905)
0.1 0.8 GO:0031781 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.1 1.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 0.6 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 1.0 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 2.4 GO:0008301 DNA binding, bending(GO:0008301)
0.1 2.1 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.3 GO:0070051 fibrinogen binding(GO:0070051) collagen V binding(GO:0070052)
0.0 1.1 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.7 GO:0070700 BMP receptor binding(GO:0070700)
0.0 3.2 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 2.2 GO:0005109 frizzled binding(GO:0005109)
0.0 1.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 1.5 GO:0004697 protein kinase C activity(GO:0004697)
0.0 1.0 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.5 GO:0003680 AT DNA binding(GO:0003680)
0.0 1.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.7 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 1.1 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 1.4 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.6 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.1 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.0 0.4 GO:0036122 BMP binding(GO:0036122)
0.0 0.1 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.5 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.4 GO:0009881 photoreceptor activity(GO:0009881)
0.0 4.6 GO:0008201 heparin binding(GO:0008201)
0.0 2.0 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.3 GO:0031433 telethonin binding(GO:0031433)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 3.7 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 0.9 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.2 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.8 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 6.6 GO:0008017 microtubule binding(GO:0008017)
0.0 0.7 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.5 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 1.7 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 1.1 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.1 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.3 GO:0048038 quinone binding(GO:0048038)
0.0 0.2 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 1.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 5.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 6.7 PID BMP PATHWAY BMP receptor signaling
0.1 1.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 19.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 2.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.7 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 1.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.8 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 1.5 ST GA13 PATHWAY G alpha 13 Pathway
0.0 3.4 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.6 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.9 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.8 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.2 ST GAQ PATHWAY G alpha q Pathway
0.0 1.0 PID AP1 PATHWAY AP-1 transcription factor network
0.0 4.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.4 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.2 14.6 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 3.7 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 7.9 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 2.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 2.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 3.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 5.0 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 3.0 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.5 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 1.6 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.5 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 4.3 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 2.0 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 2.1 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.0 0.9 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 1.9 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.5 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.1 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 1.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.6 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.6 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.7 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.4 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.2 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels