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Illumina Body Map 2: averaged replicates

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Results for ZNF274

Z-value: 1.22

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Transcription factors associated with ZNF274

Gene Symbol Gene ID Gene Info
ENSG00000171606.13 zinc finger protein 274

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF274hg19_v2_chr19_+_58694742_586948630.631.3e-04Click!

Activity profile of ZNF274 motif

Sorted Z-values of ZNF274 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_6713376 7.57 ENST00000399484.3
ENST00000544825.1
ENST00000401847.1
Uncharacterized protein
chr14_+_22409308 4.77 ENST00000390441.2
T cell receptor alpha variable 9-2
chr7_+_6714599 3.68 ENST00000328239.7
ENST00000542006.1
Uncharacterized protein
chr7_-_142240014 3.65 ENST00000390363.2
T cell receptor beta variable 9
chr20_-_1638408 2.29 ENST00000303415.3
ENST00000381583.2
signal-regulatory protein gamma
chr20_-_1638360 2.15 ENST00000216927.4
ENST00000344103.4
signal-regulatory protein gamma
chr14_-_64846033 2.02 ENST00000556556.1
CTD-2555O16.1
chr2_-_89292422 1.86 ENST00000495489.1
immunoglobulin kappa variable 1-8
chr22_+_24038593 1.72 ENST00000452208.1
ral guanine nucleotide dissociation stimulator-like 4
chr6_-_32784687 1.68 ENST00000447394.1
ENST00000438763.2
major histocompatibility complex, class II, DO beta
chr6_+_31553978 1.68 ENST00000376096.1
ENST00000376099.1
ENST00000376110.3
leukocyte specific transcript 1
chr6_+_31553901 1.57 ENST00000418507.2
ENST00000438075.2
ENST00000376100.3
ENST00000376111.4
leukocyte specific transcript 1
chr22_+_39353527 1.40 ENST00000249116.2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
chr1_-_114414316 1.39 ENST00000528414.1
ENST00000538253.1
ENST00000460620.1
ENST00000420377.2
ENST00000525799.1
ENST00000359785.5
protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
chr19_+_6887571 1.38 ENST00000250572.8
ENST00000381407.5
ENST00000312053.4
ENST00000450315.3
ENST00000381404.4
egf-like module containing, mucin-like, hormone receptor-like 1
chr22_+_22453093 1.34 ENST00000390283.2
immunoglobulin lambda variable 8-61
chr16_+_31470143 1.15 ENST00000457010.2
ENST00000563544.1
armadillo repeat containing 5
chr19_-_56109119 1.12 ENST00000587678.1
FLT3-interacting zinc finger 1
chr14_-_24047965 1.07 ENST00000397118.3
ENST00000356300.4
junctophilin 4
chr4_+_15704679 0.90 ENST00000382346.3
bone marrow stromal cell antigen 1
chr13_+_103459704 0.90 ENST00000602836.1
BIVM-ERCC5 readthrough
chr1_-_206671061 0.87 ENST00000367119.1
chromosome 1 open reading frame 147
chr5_-_74162739 0.79 ENST00000513277.1
family with sequence similarity 169, member A
chr5_-_74162605 0.78 ENST00000389156.4
ENST00000510496.1
ENST00000380515.3
family with sequence similarity 169, member A
chr16_+_29819446 0.75 ENST00000568282.1
MYC-associated zinc finger protein (purine-binding transcription factor)
chr7_-_142143973 0.73 ENST00000390373.2
T cell receptor beta variable 6-7 (non-functional)
chr17_+_73028676 0.72 ENST00000581589.1
potassium channel tetramerization domain containing 2
chr16_+_29819096 0.71 ENST00000568411.1
ENST00000563012.1
ENST00000562557.1
MYC-associated zinc finger protein (purine-binding transcription factor)
chr12_+_113344755 0.71 ENST00000550883.1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr16_+_29819372 0.70 ENST00000568544.1
ENST00000569978.1
MYC-associated zinc finger protein (purine-binding transcription factor)
chr17_+_41132564 0.69 ENST00000361677.1
ENST00000589705.1
RUN domain containing 1
chr16_+_29818857 0.65 ENST00000567444.1
MYC-associated zinc finger protein (purine-binding transcription factor)
chr6_+_30687978 0.62 ENST00000327892.8
ENST00000435534.1
tubulin, beta class I
chr4_+_15704573 0.61 ENST00000265016.4
bone marrow stromal cell antigen 1
chr17_-_37322013 0.59 ENST00000269586.7
ADP-ribosylation factor-like 5C
chr12_-_49581152 0.56 ENST00000550811.1
tubulin, alpha 1a
chr8_-_4852218 0.52 ENST00000400186.3
ENST00000602723.1
CUB and Sushi multiple domains 1
chr16_+_31470179 0.52 ENST00000538189.1
ENST00000268314.4
armadillo repeat containing 5
chr2_-_96971259 0.52 ENST00000349783.5
small nuclear ribonucleoprotein 200kDa (U5)
chr16_+_29127282 0.51 ENST00000562902.1
RP11-426C22.5
chr15_+_89164520 0.50 ENST00000332810.3
apoptosis enhancing nuclease
chr15_+_89164560 0.48 ENST00000379231.3
ENST00000559528.1
apoptosis enhancing nuclease
chr8_-_4852494 0.46 ENST00000520002.1
ENST00000602557.1
CUB and Sushi multiple domains 1
chr17_-_7145106 0.44 ENST00000577035.1
GABA(A) receptor-associated protein
chr17_-_73636019 0.44 ENST00000580707.1
RecQ protein-like 5
chr6_+_36165133 0.40 ENST00000446974.1
ENST00000454960.1
bromodomain and PHD finger containing, 3
chr2_-_42991257 0.39 ENST00000378661.2
oxoeicosanoid (OXE) receptor 1
chr8_-_19540086 0.38 ENST00000332246.6
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr2_+_11864458 0.37 ENST00000396098.1
ENST00000396099.1
ENST00000425416.2
lipin 1
chr8_-_19540266 0.34 ENST00000311540.4
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr12_-_89920030 0.34 ENST00000413530.1
ENST00000547474.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
POC1B-GALNT4 readthrough
chr20_+_60174827 0.32 ENST00000543233.1
cadherin 4, type 1, R-cadherin (retinal)
chr3_-_137893721 0.28 ENST00000505015.2
ENST00000260803.4
debranching RNA lariats 1
chr11_+_59705928 0.28 ENST00000398992.1
oocyte secreted protein 1
chrX_+_119737806 0.26 ENST00000371317.5
malignant T cell amplified sequence 1
chr3_+_50284321 0.24 ENST00000451956.1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr19_+_46498704 0.23 ENST00000595358.1
ENST00000594672.1
ENST00000536603.1
coiled-coil domain containing 61
chr2_+_178977143 0.23 ENST00000286070.5
RNA binding motif protein 45
chr11_+_16760161 0.19 ENST00000524439.1
ENST00000422258.2
ENST00000528634.1
ENST00000525684.1
chromosome 11 open reading frame 58
chr12_-_89919965 0.19 ENST00000548729.1
POC1B-GALNT4 readthrough
chr3_+_37903432 0.16 ENST00000443503.2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr19_-_19774473 0.16 ENST00000357324.6
ATPase type 13A1
chr5_+_32531893 0.13 ENST00000512913.1
SUB1 homolog (S. cerevisiae)
chr1_+_42928945 0.12 ENST00000428554.2
coiled-coil domain containing 30
chr1_-_54355430 0.11 ENST00000371399.1
ENST00000072644.1
ENST00000412288.1
Yip1 domain family, member 1
chr11_+_5757681 0.08 ENST00000317121.3
olfactory receptor, family 56, subfamily B, member 1
chr22_-_43036607 0.05 ENST00000505920.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G2
chr17_-_3461092 0.04 ENST00000301365.4
ENST00000572519.1
transient receptor potential cation channel, subfamily V, member 3

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF274

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.3 1.4 GO:0070425 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.2 1.4 GO:0070383 DNA cytosine deamination(GO:0070383)
0.1 0.5 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.1 0.7 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.1 0.3 GO:0002188 translation reinitiation(GO:0002188)
0.1 0.4 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1 1.1 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.4 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 1.5 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.0 0.9 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 3.2 GO:0050672 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.0 5.7 GO:0002377 immunoglobulin production(GO:0002377)
0.0 2.8 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.4 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.0 4.4 GO:0050870 positive regulation of T cell activation(GO:0050870)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0030314 junctional membrane complex(GO:0030314)
0.1 1.7 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 1.5 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.6 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.4 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.4 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.5 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 1.6 GO:0005637 nuclear inner membrane(GO:0005637)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.3 1.4 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.1 0.7 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.1 1.7 GO:0032395 MHC class II receptor activity(GO:0032395)
0.1 0.4 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.7 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.4 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.4 GO:1901567 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0 0.7 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.6 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 2.8 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.2 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 3.2 GO:0003823 antigen binding(GO:0003823)
0.0 1.1 GO:0030971 receptor tyrosine kinase binding(GO:0030971)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.4 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.2 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.4 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.7 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE