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Illumina Body Map 2: averaged replicates

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Results for ZNF282

Z-value: 1.00

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Transcription factors associated with ZNF282

Gene Symbol Gene ID Gene Info
ZNF282
ENSG00000170265.7 zinc finger protein 282

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF282hg19_v2_chr7_+_148892557_148892580-0.364.6e-02Click!

Activity profile of ZNF282 motif

Sorted Z-values of ZNF282 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_36989427 3.38 ENST00000354822.5
NKX2-1
NK2 homeobox 1
chr14_-_36989336 2.81 ENST00000522719.2
NKX2-1
NK2 homeobox 1
chr6_-_32151999 1.66 ENST00000375069.3
ENST00000538695.1
ENST00000438221.2
ENST00000375065.5
ENST00000450110.1
ENST00000375067.3
ENST00000375056.2
AGER
advanced glycosylation end product-specific receptor
chr6_-_32152064 1.60 ENST00000375076.4
ENST00000375070.3
AGER
advanced glycosylation end product-specific receptor
chr8_-_121825088 1.54 ENST00000520717.1
SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr6_-_32152020 1.46 ENST00000375055.2
AGER
advanced glycosylation end product-specific receptor
chr19_+_18283959 1.41 ENST00000597802.2
IFI30
interferon, gamma-inducible protein 30
chr12_-_113841678 1.21 ENST00000552280.1
ENST00000257549.4
SDS
serine dehydratase
chr17_+_7942335 0.88 ENST00000380183.4
ENST00000572022.1
ENST00000380173.2
ALOX15B
arachidonate 15-lipoxygenase, type B
chr1_+_2004901 0.83 ENST00000400921.2
PRKCZ
protein kinase C, zeta
chr1_+_2005425 0.81 ENST00000461106.2
PRKCZ
protein kinase C, zeta
chr5_+_167718604 0.80 ENST00000265293.4
WWC1
WW and C2 domain containing 1
chr12_-_127256772 0.77 ENST00000536517.1
LINC00944
long intergenic non-protein coding RNA 944
chr2_-_107502456 0.76 ENST00000419159.2
ST6GAL2
ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
chr12_+_57828521 0.73 ENST00000309668.2
INHBC
inhibin, beta C
chr6_+_144471643 0.71 ENST00000367568.4
STX11
syntaxin 11
chr6_+_139117251 0.68 ENST00000401414.3
ECT2L
epithelial cell transforming sequence 2 oncogene-like
chr15_+_38276910 0.68 ENST00000558081.2
RP11-1008C21.1
RP11-1008C21.1
chr2_+_232260254 0.68 ENST00000287590.5
B3GNT7
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
chr10_+_11865347 0.63 ENST00000277570.5
PROSER2
proline and serine-rich protein 2
chr1_+_2005126 0.62 ENST00000495347.1
PRKCZ
protein kinase C, zeta
chr6_+_10585979 0.59 ENST00000265012.4
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr6_+_148593425 0.55 ENST00000367469.1
SASH1
SAM and SH3 domain containing 1
chr11_-_321340 0.52 ENST00000526811.1
IFITM3
interferon induced transmembrane protein 3
chr1_+_226250379 0.52 ENST00000366815.3
ENST00000366814.3
H3F3A
H3 histone, family 3A
chr17_+_7942424 0.50 ENST00000573359.1
ALOX15B
arachidonate 15-lipoxygenase, type B
chr4_-_74904398 0.49 ENST00000296026.4
CXCL3
chemokine (C-X-C motif) ligand 3
chr8_+_74888417 0.48 ENST00000517439.1
ENST00000312184.5
TMEM70
transmembrane protein 70
chr16_+_50727479 0.45 ENST00000531674.1
NOD2
nucleotide-binding oligomerization domain containing 2
chr9_+_126777676 0.45 ENST00000488674.2
LHX2
LIM homeobox 2
chr3_+_10312604 0.40 ENST00000426850.1
TATDN2
TatD DNase domain containing 2
chr12_-_46766577 0.39 ENST00000256689.5
SLC38A2
solute carrier family 38, member 2
chr22_-_50970919 0.37 ENST00000329363.4
ENST00000437588.1
ODF3B
outer dense fiber of sperm tails 3B
chr17_-_79905109 0.36 ENST00000409745.2
MYADML2
myeloid-associated differentiation marker-like 2
chr13_+_31309645 0.33 ENST00000380490.3
ALOX5AP
arachidonate 5-lipoxygenase-activating protein
chr10_+_51572408 0.32 ENST00000374082.1
NCOA4
nuclear receptor coactivator 4
chr22_-_50970566 0.32 ENST00000405135.1
ENST00000401779.1
ODF3B
outer dense fiber of sperm tails 3B
chr17_-_47786375 0.32 ENST00000511657.1
SLC35B1
solute carrier family 35, member B1
chr6_+_139349903 0.31 ENST00000461027.1
ABRACL
ABRA C-terminal like
chr5_+_66675200 0.30 ENST00000503106.1
RP11-434D9.1
RP11-434D9.1
chr1_-_24151892 0.30 ENST00000235958.4
HMGCL
3-hydroxymethyl-3-methylglutaryl-CoA lyase
chr11_+_111957497 0.30 ENST00000375549.3
ENST00000528182.1
ENST00000528048.1
ENST00000528021.1
ENST00000526592.1
ENST00000525291.1
SDHD
succinate dehydrogenase complex, subunit D, integral membrane protein
chrX_-_47004878 0.30 ENST00000377811.3
NDUFB11
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa
chr5_+_175299743 0.30 ENST00000502265.1
CPLX2
complexin 2
chr10_+_51572339 0.29 ENST00000344348.6
NCOA4
nuclear receptor coactivator 4
chr1_-_24151903 0.29 ENST00000436439.2
ENST00000374490.3
HMGCL
3-hydroxymethyl-3-methylglutaryl-CoA lyase
chr2_+_219283815 0.28 ENST00000248444.5
ENST00000454069.1
ENST00000392114.2
VIL1
villin 1
chr5_+_7869217 0.28 ENST00000264668.2
ENST00000514220.1
ENST00000341013.6
ENST00000440940.2
ENST00000502550.1
ENST00000506877.1
MTRR
5-methyltetrahydrofolate-homocysteine methyltransferase reductase
chr1_+_27320176 0.28 ENST00000522111.2
TRNP1
TMF1-regulated nuclear protein 1
chr11_+_100784231 0.28 ENST00000531183.1
ARHGAP42
Rho GTPase activating protein 42
chr22_-_50970506 0.28 ENST00000428989.2
ENST00000403326.1
ODF3B
outer dense fiber of sperm tails 3B
chr2_-_188378368 0.28 ENST00000392365.1
ENST00000435414.1
TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr8_+_124968225 0.28 ENST00000399018.1
FER1L6
fer-1-like 6 (C. elegans)
chr12_-_122296755 0.28 ENST00000289004.4
HPD
4-hydroxyphenylpyruvate dioxygenase
chr6_+_32938692 0.28 ENST00000443797.2
BRD2
bromodomain containing 2
chr12_-_127256858 0.27 ENST00000542248.1
ENST00000540684.1
LINC00944
long intergenic non-protein coding RNA 944
chr21_+_35747773 0.27 ENST00000399292.3
ENST00000399299.1
ENST00000399295.2
SMIM11
small integral membrane protein 11
chr18_+_43753500 0.27 ENST00000587591.1
ENST00000588730.1
C18orf25
chromosome 18 open reading frame 25
chr20_-_62493217 0.27 ENST00000601296.1
C20ORF135
C20ORF135
chr1_+_47799446 0.26 ENST00000371873.5
CMPK1
cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
chr5_+_156887027 0.26 ENST00000435489.2
ENST00000311946.7
NIPAL4
NIPA-like domain containing 4
chr6_+_32938665 0.26 ENST00000374831.4
ENST00000395289.2
BRD2
bromodomain containing 2
chr18_-_54318353 0.24 ENST00000590954.1
ENST00000540155.1
TXNL1
thioredoxin-like 1
chr11_-_6633799 0.24 ENST00000299424.4
TAF10
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
chr1_+_47799542 0.24 ENST00000471289.2
ENST00000450808.2
CMPK1
cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
chr16_+_29802036 0.23 ENST00000561482.1
ENST00000160827.4
ENST00000569636.2
ENST00000400750.2
KIF22
kinesin family member 22
chr5_-_175788758 0.23 ENST00000510164.1
ENST00000533553.1
ENST00000504688.1
ENST00000393725.2
ENST00000503082.1
ENST00000506983.1
KIAA1191
KIAA1191
chr3_-_180707306 0.21 ENST00000479269.1
DNAJC19
DnaJ (Hsp40) homolog, subfamily C, member 19
chr6_-_79944336 0.21 ENST00000344726.5
ENST00000275036.7
HMGN3
high mobility group nucleosomal binding domain 3
chr17_+_42422629 0.20 ENST00000589536.1
ENST00000587109.1
ENST00000587518.1
GRN
granulin
chrX_-_13835147 0.20 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chr4_+_52709229 0.20 ENST00000334635.5
ENST00000381441.3
ENST00000381437.4
DCUN1D4
DCN1, defective in cullin neddylation 1, domain containing 4
chr19_+_7953384 0.19 ENST00000306708.6
LRRC8E
leucine rich repeat containing 8 family, member E
chr3_+_45928029 0.19 ENST00000422395.1
ENST00000355983.2
CCR9
chemokine (C-C motif) receptor 9
chr17_-_73389854 0.18 ENST00000578961.1
ENST00000392564.1
ENST00000582582.1
GRB2
growth factor receptor-bound protein 2
chr1_+_35247859 0.17 ENST00000373362.3
GJB3
gap junction protein, beta 3, 31kDa
chr14_+_71788096 0.17 ENST00000557151.1
SIPA1L1
signal-induced proliferation-associated 1 like 1
chr6_+_10748019 0.17 ENST00000543878.1
ENST00000461342.1
ENST00000475942.1
ENST00000379530.3
ENST00000473276.1
ENST00000481240.1
ENST00000467317.1
SYCP2L
TMEM14B
synaptonemal complex protein 2-like
transmembrane protein 14B
chr11_+_82904746 0.17 ENST00000393389.3
ENST00000528722.1
ANKRD42
ankyrin repeat domain 42
chr18_-_47018869 0.17 ENST00000583036.1
ENST00000580261.1
RPL17
ribosomal protein L17
chr17_-_73937028 0.17 ENST00000586631.2
FBF1
Fas (TNFRSF6) binding factor 1
chr10_+_114135004 0.17 ENST00000393081.1
ACSL5
acyl-CoA synthetase long-chain family member 5
chr19_-_51340469 0.16 ENST00000326856.4
KLK15
kallikrein-related peptidase 15
chr10_+_95753714 0.16 ENST00000260766.3
PLCE1
phospholipase C, epsilon 1
chrX_-_13835461 0.16 ENST00000316715.4
ENST00000356942.5
GPM6B
glycoprotein M6B
chr17_+_42422637 0.15 ENST00000053867.3
ENST00000588143.1
GRN
granulin
chr18_-_47017956 0.15 ENST00000584895.1
ENST00000332968.6
ENST00000580210.1
ENST00000579408.1
RPL17-C18orf32
RPL17
RPL17-C18orf32 readthrough
ribosomal protein L17
chr2_+_233415488 0.15 ENST00000454501.1
EIF4E2
eukaryotic translation initiation factor 4E family member 2
chr2_+_233415363 0.14 ENST00000409514.1
ENST00000409098.1
ENST00000409495.1
ENST00000409167.3
ENST00000409322.1
ENST00000409394.1
EIF4E2
eukaryotic translation initiation factor 4E family member 2
chr20_-_2451395 0.14 ENST00000339610.6
ENST00000381342.2
ENST00000438552.2
SNRPB
small nuclear ribonucleoprotein polypeptides B and B1
chr6_+_10747986 0.14 ENST00000379542.5
TMEM14B
transmembrane protein 14B
chr12_+_4758264 0.14 ENST00000266544.5
NDUFA9
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa
chr6_+_139349817 0.14 ENST00000367660.3
ABRACL
ABRA C-terminal like
chr19_+_39390587 0.14 ENST00000572515.1
ENST00000392079.3
ENST00000575359.1
ENST00000313582.5
NFKBIB
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr10_-_126480381 0.13 ENST00000368836.2
METTL10
methyltransferase like 10
chr18_-_47018897 0.13 ENST00000418495.1
RPL17
ribosomal protein L17
chr13_+_50656307 0.12 ENST00000378180.4
DLEU1
deleted in lymphocytic leukemia 1 (non-protein coding)
chr18_-_47018769 0.12 ENST00000583637.1
ENST00000578528.1
ENST00000578532.1
ENST00000580387.1
ENST00000579248.1
ENST00000581373.1
RPL17
ribosomal protein L17
chr1_-_154178803 0.12 ENST00000368525.3
C1orf189
chromosome 1 open reading frame 189
chr8_-_28347737 0.12 ENST00000517673.1
ENST00000518734.1
ENST00000346498.2
ENST00000380254.2
FBXO16
F-box protein 16
chr14_+_55590646 0.12 ENST00000553493.1
LGALS3
lectin, galactoside-binding, soluble, 3
chr12_-_9102549 0.11 ENST00000000412.3
M6PR
mannose-6-phosphate receptor (cation dependent)
chr17_+_42422662 0.11 ENST00000593167.1
ENST00000585512.1
ENST00000591740.1
ENST00000592783.1
ENST00000587387.1
ENST00000588237.1
ENST00000589265.1
GRN
granulin
chr6_-_17706618 0.11 ENST00000262077.2
ENST00000537253.1
NUP153
nucleoporin 153kDa
chr10_-_114206649 0.11 ENST00000369404.3
ENST00000369405.3
ZDHHC6
zinc finger, DHHC-type containing 6
chr3_-_170588163 0.10 ENST00000295830.8
RPL22L1
ribosomal protein L22-like 1
chr11_+_66278080 0.10 ENST00000318312.7
ENST00000526815.1
ENST00000537537.1
ENST00000525809.1
ENST00000455748.2
ENST00000393994.2
BBS1
Bardet-Biedl syndrome 1
chr2_+_108602971 0.10 ENST00000409059.1
ENST00000540517.1
ENST00000264047.2
SLC5A7
solute carrier family 5 (sodium/choline cotransporter), member 7
chr13_-_95248511 0.10 ENST00000261296.5
TGDS
TDP-glucose 4,6-dehydratase
chr4_+_88343952 0.09 ENST00000440591.2
NUDT9
nudix (nucleoside diphosphate linked moiety X)-type motif 9
chr15_-_44955842 0.09 ENST00000427534.2
ENST00000559193.1
ENST00000261866.7
ENST00000535302.2
ENST00000558319.1
SPG11
spastic paraplegia 11 (autosomal recessive)
chr8_-_75233563 0.09 ENST00000342232.4
JPH1
junctophilin 1
chr4_+_88343717 0.09 ENST00000302174.4
ENST00000512216.1
ENST00000473942.1
NUDT9
nudix (nucleoside diphosphate linked moiety X)-type motif 9
chr19_+_30097181 0.09 ENST00000586420.1
ENST00000221770.3
ENST00000392279.3
ENST00000590688.1
POP4
processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)
chr17_-_61996160 0.09 ENST00000458650.2
ENST00000351388.4
ENST00000323322.5
GH1
growth hormone 1
chr19_+_44617511 0.08 ENST00000262894.6
ENST00000588926.1
ENST00000592780.1
ZNF225
zinc finger protein 225
chr2_-_9695847 0.08 ENST00000310823.3
ENST00000497134.1
ADAM17
ADAM metallopeptidase domain 17
chr1_-_248738080 0.08 ENST00000328782.2
OR2T34
olfactory receptor, family 2, subfamily T, member 34
chr1_+_160313062 0.08 ENST00000294785.5
ENST00000368063.1
ENST00000437169.1
NCSTN
nicastrin
chr3_-_170587974 0.08 ENST00000463836.1
RPL22L1
ribosomal protein L22-like 1
chr18_+_54318893 0.08 ENST00000593058.1
WDR7
WD repeat domain 7
chr19_-_58220517 0.08 ENST00000512439.2
ENST00000426889.1
ZNF154
zinc finger protein 154
chr1_-_2126174 0.07 ENST00000400919.3
ENST00000420515.1
ENST00000378543.2
ENST00000400918.3
C1orf86
chromosome 1 open reading frame 86
chr1_+_145507587 0.07 ENST00000330165.8
ENST00000369307.3
RBM8A
RNA binding motif protein 8A
chr1_-_2126192 0.07 ENST00000378546.4
C1orf86
chromosome 1 open reading frame 86
chr18_+_54318566 0.06 ENST00000589935.1
ENST00000357574.3
WDR7
WD repeat domain 7
chr16_+_66586461 0.06 ENST00000264001.4
ENST00000351137.4
ENST00000345436.4
ENST00000362093.4
ENST00000417030.2
ENST00000527729.1
ENST00000532838.1
CKLF
CKLF-CMTM1
chemokine-like factor
CKLF-CMTM1 readthrough
chr2_+_242289502 0.06 ENST00000451310.1
SEPT2
septin 2
chr18_+_54318616 0.06 ENST00000254442.3
WDR7
WD repeat domain 7
chr1_+_150122034 0.06 ENST00000025469.6
ENST00000369124.4
PLEKHO1
pleckstrin homology domain containing, family O member 1
chr12_+_93964158 0.05 ENST00000549206.1
SOCS2
suppressor of cytokine signaling 2
chr2_-_68479614 0.05 ENST00000234310.3
PPP3R1
protein phosphatase 3, regulatory subunit B, alpha
chr19_+_39390320 0.04 ENST00000576510.1
NFKBIB
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr7_+_16828866 0.04 ENST00000597084.1
AC073333.1
Uncharacterized protein
chr17_-_27188984 0.04 ENST00000582320.2
MIR144
microRNA 451b
chr5_-_7869108 0.04 ENST00000264669.5
ENST00000507572.1
ENST00000504695.1
FASTKD3
FAST kinase domains 3
chr7_+_139026057 0.04 ENST00000541515.3
LUC7L2
LUC7-like 2 (S. cerevisiae)
chr20_-_62284766 0.03 ENST00000370053.1
STMN3
stathmin-like 3
chr4_+_39460659 0.03 ENST00000513731.1
LIAS
lipoic acid synthetase
chr10_+_114206956 0.01 ENST00000432306.1
ENST00000393077.2
VTI1A
vesicle transport through interaction with t-SNAREs 1A
chr16_+_30207122 0.01 ENST00000395137.2
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr1_-_108735440 0.01 ENST00000370041.4
SLC25A24
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr17_+_41323204 0.01 ENST00000542611.1
ENST00000590996.1
ENST00000389312.4
ENST00000589872.1
NBR1
neighbor of BRCA1 gene 1
chr14_+_58711539 0.01 ENST00000216455.4
ENST00000412908.2
ENST00000557508.1
PSMA3
proteasome (prosome, macropain) subunit, alpha type, 3
chr16_+_29467780 0.01 ENST00000395400.3
SULT1A4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
chr9_+_34652164 0.01 ENST00000441545.2
ENST00000553620.1
IL11RA
interleukin 11 receptor, alpha
chr12_+_122150646 0.00 ENST00000449592.2
TMEM120B
transmembrane protein 120B
chr15_-_83736091 0.00 ENST00000261721.4
BTBD1
BTB (POZ) domain containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF282

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.7 GO:1904596 regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904596) negative regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904597) regulation of advanced glycation end-product receptor activity(GO:1904603) negative regulation of advanced glycation end-product receptor activity(GO:1904604) negative regulation of connective tissue replacement(GO:1905204)
0.5 6.2 GO:0021759 globus pallidus development(GO:0021759)
0.2 2.3 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.2 1.4 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 1.2 GO:0006565 L-serine catabolic process(GO:0006565)
0.1 0.5 GO:0031508 pericentric heterochromatin assembly(GO:0031508) regulation of chromosome condensation(GO:0060623)
0.1 0.5 GO:0060585 detection of peptidoglycan(GO:0032499) activation of MAPK activity involved in innate immune response(GO:0035419) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585) positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.1 0.5 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.1 0.3 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.1 0.6 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 0.3 GO:0043418 homocysteine catabolic process(GO:0043418)
0.1 0.5 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.1 0.2 GO:0046709 IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709)
0.1 0.3 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 0.6 GO:0006552 leucine catabolic process(GO:0006552)
0.1 0.8 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.3 GO:2001300 lipoxin metabolic process(GO:2001300)
0.1 0.5 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0 0.2 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.0 0.3 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.1 GO:0046832 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.0 0.3 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.3 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.3 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0033023 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0 0.7 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.2 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:2000521 negative regulation of immunological synapse formation(GO:2000521)
0.0 0.4 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.7 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.0 0.3 GO:0032328 alanine transport(GO:0032328)
0.0 0.5 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.3 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.5 GO:0046597 response to interferon-alpha(GO:0035455) negative regulation of viral entry into host cell(GO:0046597)
0.0 0.2 GO:0070365 hepatocyte differentiation(GO:0070365)
0.0 0.8 GO:0097503 sialylation(GO:0097503)
0.0 0.6 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.1 GO:1900619 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0 0.1 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.3 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 1.4 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.0 0.7 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 GO:0045179 apical cortex(GO:0045179)
0.1 0.3 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 0.5 GO:0001740 Barr body(GO:0001740)
0.0 0.6 GO:0044754 autolysosome(GO:0044754)
0.0 0.2 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.3 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 1.2 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0000125 PCAF complex(GO:0000125)
0.0 4.5 GO:0001650 fibrillar center(GO:0001650)
0.0 0.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.1 GO:0070195 growth hormone receptor complex(GO:0070195)
0.0 0.1 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.3 GO:0005845 mRNA cap binding complex(GO:0005845)
0.0 0.1 GO:0005655 ribonuclease MRP complex(GO:0000172) nucleolar ribonuclease P complex(GO:0005655)
0.0 0.3 GO:0032433 filopodium tip(GO:0032433)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.7 GO:1904599 advanced glycation end-product binding(GO:1904599)
0.4 1.2 GO:0004794 L-threonine ammonia-lyase activity(GO:0004794)
0.3 1.4 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.3 6.2 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1 0.7 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.5 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 0.6 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.1 0.3 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 0.3 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.1 0.3 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 0.8 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 2.3 GO:0043274 phospholipase binding(GO:0043274)
0.1 0.6 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.2 GO:0019144 ADP-sugar diphosphatase activity(GO:0019144)
0.0 0.5 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.3 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.3 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.0 0.1 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.5 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.4 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.5 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0033265 choline binding(GO:0033265)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 1.6 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors(GO:0016667)
0.0 0.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.7 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.0 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 6.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.8 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 2.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 0.7 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.7 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.8 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.6 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0 0.1 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.7 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.4 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.2 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.2 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates