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Illumina Body Map 2: averaged replicates
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Results for ZNF35
Z-value: 0.94
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Transcription factors associated with ZNF35
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ZNF35 | hg19_v2_chr3_+_44690211_44690267 | 0.12 | 5.3e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr3_-_148939598 Show fit | 1.49 |
ENST00000455472.3
|
ceruloplasmin (ferroxidase) |
|
| chr3_-_148939835 Show fit | 1.44 |
ENST00000264613.6
|
ceruloplasmin (ferroxidase) |
|
| chr16_-_77465450 Show fit | 1.03 |
ENST00000562345.1
|
ADAM metallopeptidase with thrombospondin type 1 motif, 18 |
|
| chr10_+_74653330 Show fit | 0.98 |
ENST00000334011.5
|
oncoprotein induced transcript 3 |
|
| chr6_-_135271219 Show fit | 0.87 |
ENST00000367847.2
ENST00000367845.2 |
aldehyde dehydrogenase 8 family, member A1 |
|
| chr7_-_83824449 Show fit | 0.85 |
ENST00000420047.1
|
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A |
|
| chr7_-_83824169 Show fit | 0.80 |
ENST00000265362.4
|
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A |
|
| chr4_+_70796784 Show fit | 0.73 |
ENST00000246891.4
ENST00000444405.3 |
casein alpha s1 |
|
| chr8_-_95274536 Show fit | 0.71 |
ENST00000297596.2
ENST00000396194.2 |
GTP binding protein overexpressed in skeletal muscle |
|
| chr10_-_52645416 Show fit | 0.71 |
ENST00000374001.2
ENST00000373997.3 ENST00000373995.3 ENST00000282641.2 ENST00000395495.1 ENST00000414883.1 |
APOBEC1 complementation factor |
Network of associatons between targets according to the STRING database.
First level regulatory network of ZNF35
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.9 | GO:0006825 | copper ion transport(GO:0006825) |
| 0.4 | 1.6 | GO:1903045 | neural crest cell migration involved in sympathetic nervous system development(GO:1903045) |
| 0.1 | 1.1 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
| 0.0 | 1.0 | GO:0090331 | negative regulation of platelet aggregation(GO:0090331) |
| 0.0 | 1.0 | GO:0006688 | glycosphingolipid biosynthetic process(GO:0006688) |
| 0.1 | 0.9 | GO:0042905 | 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905) |
| 0.2 | 0.7 | GO:1901842 | negative regulation of high voltage-gated calcium channel activity(GO:1901842) |
| 0.0 | 0.7 | GO:0021952 | central nervous system projection neuron axonogenesis(GO:0021952) |
| 0.2 | 0.6 | GO:1903980 | negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973) positive regulation of microglial cell activation(GO:1903980) |
| 0.1 | 0.6 | GO:0021615 | glossopharyngeal nerve morphogenesis(GO:0021615) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 1.1 | GO:0030895 | apolipoprotein B mRNA editing enzyme complex(GO:0030895) |
| 0.0 | 0.7 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.1 | 0.5 | GO:0060201 | clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201) |
| 0.0 | 0.5 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.0 | 0.5 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.0 | 0.5 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.0 | 0.4 | GO:0035867 | alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867) |
| 0.0 | 0.4 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.0 | 0.4 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.0 | 0.2 | GO:1990111 | spermatoproteasome complex(GO:1990111) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 2.9 | GO:0016724 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 0.1 | 1.6 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.1 | 1.0 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
| 0.1 | 0.9 | GO:0001758 | retinal dehydrogenase activity(GO:0001758) |
| 0.1 | 0.6 | GO:0005157 | macrophage colony-stimulating factor receptor binding(GO:0005157) |
| 0.1 | 0.5 | GO:0050692 | DBD domain binding(GO:0050692) |
| 0.0 | 0.5 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
| 0.0 | 0.5 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.1 | 0.4 | GO:0090554 | phosphatidylcholine-translocating ATPase activity(GO:0090554) |
| 0.1 | 0.4 | GO:0070699 | type II activin receptor binding(GO:0070699) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.4 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.9 | REACTOME METAL ION SLC TRANSPORTERS | Genes involved in Metal ion SLC transporters |
| 0.1 | 1.6 | REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
| 0.0 | 0.5 | REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Norepinephrine Neurotransmitter Release Cycle |
| 0.0 | 0.5 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.0 | 0.4 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
| 0.0 | 0.3 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol |
| 0.0 | 0.2 | REACTOME SEROTONIN RECEPTORS | Genes involved in Serotonin receptors |