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Illumina Body Map 2: averaged replicates
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Results for ZNF524
Z-value: 1.55
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Transcription factors associated with ZNF524
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ZNF524 | hg19_v2_chr19_+_56111680_56111735 | 0.58 | 5.3e-04 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr3_-_44465475 Show fit | 2.04 |
ENST00000416124.1
|
long intergenic non-protein coding RNA 694 |
|
| chr19_+_50015870 Show fit | 1.95 |
ENST00000599701.1
|
Fc fragment of IgG, receptor, transporter, alpha |
|
| chr19_+_50016411 Show fit | 1.81 |
ENST00000426395.3
ENST00000600273.1 ENST00000599988.1 |
Fc fragment of IgG, receptor, transporter, alpha |
|
| chr12_+_54402790 Show fit | 1.72 |
ENST00000040584.4
|
homeobox C8 |
|
| chr19_+_50016610 Show fit | 1.59 |
ENST00000596975.1
|
Fc fragment of IgG, receptor, transporter, alpha |
|
| chr12_+_54378923 Show fit | 1.58 |
ENST00000303460.4
|
homeobox C10 |
|
| chr5_+_135383008 Show fit | 1.52 |
ENST00000508767.1
ENST00000604555.1 |
transforming growth factor, beta-induced, 68kDa |
|
| chr7_+_142012967 Show fit | 1.48 |
ENST00000390357.3
|
T cell receptor beta variable 4-1 |
|
| chr19_+_35645817 Show fit | 1.47 |
ENST00000423817.3
|
FXYD domain containing ion transport regulator 5 |
|
| chr19_+_51630287 Show fit | 1.45 |
ENST00000599948.1
|
sialic acid binding Ig-like lectin 9 |
Network of associatons between targets according to the STRING database.
First level regulatory network of ZNF524
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 8.2 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
| 1.8 | 5.4 | GO:0002416 | IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416) |
| 0.1 | 4.4 | GO:1901998 | toxin transport(GO:1901998) |
| 0.0 | 3.4 | GO:0051225 | spindle assembly(GO:0051225) |
| 0.7 | 3.3 | GO:0009439 | cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440) |
| 0.0 | 3.3 | GO:0006910 | phagocytosis, recognition(GO:0006910) |
| 0.9 | 2.8 | GO:0046586 | regulation of calcium-dependent cell-cell adhesion(GO:0046586) |
| 0.2 | 2.7 | GO:0021520 | spinal cord motor neuron cell fate specification(GO:0021520) |
| 0.0 | 2.3 | GO:0010972 | negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) |
| 0.0 | 2.1 | GO:0007286 | spermatid development(GO:0007286) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 6.2 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.0 | 5.7 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.1 | 5.4 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.0 | 5.3 | GO:0030667 | secretory granule membrane(GO:0030667) |
| 0.0 | 4.3 | GO:0000922 | spindle pole(GO:0000922) |
| 0.0 | 4.1 | GO:0101003 | ficolin-1-rich granule membrane(GO:0101003) |
| 0.1 | 3.5 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
| 0.2 | 2.7 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) |
| 0.0 | 1.9 | GO:0005762 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 0.1 | 1.8 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 17.3 | GO:0043565 | sequence-specific DNA binding(GO:0043565) |
| 0.0 | 11.6 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.0 | 7.2 | GO:0005125 | cytokine activity(GO:0005125) |
| 1.1 | 5.4 | GO:0019770 | IgG receptor activity(GO:0019770) |
| 0.0 | 4.5 | GO:0003714 | transcription corepressor activity(GO:0003714) |
| 0.1 | 3.5 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.8 | 3.1 | GO:0016784 | 3-mercaptopyruvate sulfurtransferase activity(GO:0016784) |
| 0.0 | 2.5 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.0 | 2.2 | GO:0005518 | collagen binding(GO:0005518) |
| 0.1 | 2.0 | GO:0008494 | translation activator activity(GO:0008494) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 6.2 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.0 | 5.6 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.1 | 4.5 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
| 0.1 | 3.7 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.0 | 2.5 | PID AURORA A PATHWAY | Aurora A signaling |
| 0.0 | 2.5 | ST T CELL SIGNAL TRANSDUCTION | T Cell Signal Transduction |
| 0.0 | 2.1 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.0 | 1.7 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.0 | 1.6 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
| 0.0 | 1.5 | PID ARF6 PATHWAY | Arf6 signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 6.7 | REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION | Genes involved in 3' -UTR-mediated translational regulation |
| 0.1 | 5.6 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.0 | 2.7 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.0 | 2.3 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.1 | 2.1 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 0.1 | 1.9 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
| 0.0 | 1.6 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 0.0 | 1.6 | REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
| 0.0 | 1.6 | REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
| 0.0 | 1.6 | REACTOME HOST INTERACTIONS OF HIV FACTORS | Genes involved in Host Interactions of HIV factors |