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Illumina Body Map 2: averaged replicates

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Results for ZNF740_ZNF219

Z-value: 2.34

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Transcription factors associated with ZNF740_ZNF219

Gene Symbol Gene ID Gene Info
ENSG00000139651.9 ZNF740
ENSG00000165804.11 ZNF219

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF219hg19_v2_chr14_-_21562671_21562702-0.451.1e-02Click!
ZNF740hg19_v2_chr12_+_53574464_53574539-0.048.1e-01Click!

Activity profile of ZNF740_ZNF219 motif

Sorted Z-values of ZNF740_ZNF219 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF740_ZNF219

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr6_-_32157947 7.42 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr20_-_22565101 5.63 ENST00000419308.2
FOXA2
forkhead box A2
chr11_-_46142948 4.63 ENST00000257821.4
PHF21A
PHD finger protein 21A
chr16_+_30675654 4.46 ENST00000287468.5
ENST00000395073.2
FBRS
fibrosin
chr18_+_3449821 4.14 ENST00000407501.2
ENST00000405385.3
ENST00000546979.1
TGIF1
TGFB-induced factor homeobox 1
chr9_-_20622478 4.08 ENST00000355930.6
ENST00000380338.4
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr11_-_46142615 4.07 ENST00000529734.1
ENST00000323180.6
PHF21A
PHD finger protein 21A
chr6_+_149638876 3.83 ENST00000392282.1
TAB2
TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr2_-_148779106 3.65 ENST00000416719.1
ENST00000264169.2
ORC4
origin recognition complex, subunit 4
chr11_-_46142505 3.56 ENST00000524497.1
ENST00000418153.2
PHF21A
PHD finger protein 21A
chr8_+_95653302 3.54 ENST00000423620.2
ENST00000433389.2
ESRP1
epithelial splicing regulatory protein 1
chr18_+_3449695 3.44 ENST00000343820.5
TGIF1
TGFB-induced factor homeobox 1
chr1_+_43148625 3.41 ENST00000436427.1
YBX1
Y box binding protein 1
chr8_+_95653373 3.38 ENST00000358397.5
ESRP1
epithelial splicing regulatory protein 1
chr12_-_57522813 3.15 ENST00000556155.1
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr20_-_52210368 3.13 ENST00000371471.2
ZNF217
zinc finger protein 217
chr12_+_54378849 3.13 ENST00000515593.1
HOXC10
homeobox C10
chr8_+_95653427 3.10 ENST00000454170.2
ESRP1
epithelial splicing regulatory protein 1
chr5_+_137688285 3.08 ENST00000314358.5
KDM3B
lysine (K)-specific demethylase 3B
chr17_+_55333876 2.89 ENST00000284073.2
MSI2
musashi RNA-binding protein 2
chr2_+_5832799 2.87 ENST00000322002.3
SOX11
SRY (sex determining region Y)-box 11
chr12_+_57853918 2.73 ENST00000532291.1
ENST00000543426.1
ENST00000228682.2
ENST00000546141.1
GLI1
GLI family zinc finger 1
chr12_+_53774423 2.68 ENST00000426431.2
SP1
Sp1 transcription factor
chr17_+_42634844 2.67 ENST00000315323.3
FZD2
frizzled family receptor 2
chr3_+_184032919 2.65 ENST00000427845.1
ENST00000342981.4
ENST00000319274.6
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr15_-_61521495 2.63 ENST00000335670.6
RORA
RAR-related orphan receptor A
chr15_-_41408409 2.63 ENST00000361937.3
INO80
INO80 complex subunit
chr18_+_3450161 2.56 ENST00000551402.1
ENST00000577543.1
TGIF1
TGFB-induced factor homeobox 1
chr12_-_6715808 2.56 ENST00000545584.1
CHD4
chromodomain helicase DNA binding protein 4
chr13_-_52027134 2.51 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6
integrator complex subunit 6
chr17_+_36861735 2.48 ENST00000378137.5
ENST00000325718.7
MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr3_-_113415441 2.45 ENST00000491165.1
ENST00000316407.4
KIAA2018
KIAA2018
chr3_-_171178157 2.42 ENST00000465393.1
ENST00000436636.2
ENST00000369326.5
ENST00000538048.1
ENST00000341852.6
TNIK
TRAF2 and NCK interacting kinase
chr16_+_29817841 2.40 ENST00000322945.6
ENST00000562337.1
ENST00000566906.2
ENST00000563402.1
ENST00000219782.6
MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr2_+_149402553 2.39 ENST00000258484.6
ENST00000409654.1
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr12_+_53845879 2.32 ENST00000359282.5
ENST00000603815.1
ENST00000447282.1
ENST00000437231.1
ENST00000549863.1
ENST00000359462.5
ENST00000550520.2
ENST00000546463.1
ENST00000552296.2
PCBP2
poly(rC) binding protein 2
chr5_+_133861339 2.31 ENST00000282605.4
ENST00000361895.2
ENST00000402835.1
PHF15
jade family PHD finger 2
chr17_+_55334364 2.30 ENST00000322684.3
ENST00000579590.1
MSI2
musashi RNA-binding protein 2
chr19_-_36233332 2.26 ENST00000592537.1
ENST00000246532.1
ENST00000344990.3
ENST00000588992.1
IGFLR1
IGF-like family receptor 1
chr17_-_7141490 2.20 ENST00000574236.1
ENST00000572789.1
PHF23
PHD finger protein 23
chr6_+_31865552 2.19 ENST00000469372.1
ENST00000497706.1
C2
complement component 2
chr7_+_21467642 2.18 ENST00000222584.3
ENST00000432066.2
SP4
Sp4 transcription factor
chr17_+_7788104 2.17 ENST00000380358.4
CHD3
chromodomain helicase DNA binding protein 3
chr1_+_154975110 2.14 ENST00000535420.1
ENST00000368426.3
ZBTB7B
zinc finger and BTB domain containing 7B
chr17_-_46703826 2.14 ENST00000550387.1
ENST00000311177.5
HOXB9
homeobox B9
chr17_-_46692457 2.13 ENST00000468443.1
HOXB8
homeobox B8
chr2_-_174828892 2.12 ENST00000418194.2
SP3
Sp3 transcription factor
chr3_+_184033551 2.07 ENST00000456033.1
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr6_-_34664612 2.05 ENST00000374023.3
ENST00000374026.3
C6orf106
chromosome 6 open reading frame 106
chr17_+_43239191 2.01 ENST00000589230.1
HEXIM2
hexamethylene bis-acetamide inducible 2
chr10_-_13390021 1.99 ENST00000537130.1
SEPHS1
selenophosphate synthetase 1
chr3_-_88108212 1.99 ENST00000482016.1
CGGBP1
CGG triplet repeat binding protein 1
chr3_+_107243204 1.98 ENST00000456817.1
ENST00000458458.1
BBX
bobby sox homolog (Drosophila)
chr19_-_40324255 1.97 ENST00000593685.1
ENST00000600611.1
DYRK1B
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr2_-_61697862 1.96 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr19_+_50094866 1.96 ENST00000418929.2
PRR12
proline rich 12
chr12_+_57522692 1.96 ENST00000554174.1
LRP1
low density lipoprotein receptor-related protein 1
chr3_+_184033135 1.95 ENST00000424196.1
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr3_-_88108192 1.95 ENST00000309534.6
CGGBP1
CGG triplet repeat binding protein 1
chr6_-_151712673 1.91 ENST00000325144.4
ZBTB2
zinc finger and BTB domain containing 2
chr10_+_114709999 1.90 ENST00000355995.4
ENST00000545257.1
ENST00000543371.1
ENST00000536810.1
ENST00000355717.4
ENST00000538897.1
ENST00000534894.1
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr2_-_61765315 1.89 ENST00000406957.1
ENST00000401558.2
XPO1
exportin 1 (CRM1 homolog, yeast)
chr17_-_58469474 1.88 ENST00000300896.4
USP32
ubiquitin specific peptidase 32
chr3_-_171177852 1.88 ENST00000284483.8
ENST00000475336.1
ENST00000357327.5
ENST00000460047.1
ENST00000488470.1
ENST00000470834.1
TNIK
TRAF2 and NCK interacting kinase
chr20_+_57466461 1.88 ENST00000306090.10
GNAS
GNAS complex locus
chr17_+_43238438 1.88 ENST00000593138.1
ENST00000586681.1
HEXIM2
hexamethylene bis-acetamide inducible 2
chr16_+_30709530 1.87 ENST00000411466.2
SRCAP
Snf2-related CREBBP activator protein
chr1_+_43148059 1.86 ENST00000321358.7
ENST00000332220.6
YBX1
Y box binding protein 1
chr2_-_208030647 1.84 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr2_-_145277882 1.84 ENST00000465070.1
ENST00000444559.1
ZEB2
zinc finger E-box binding homeobox 2
chr9_-_127269661 1.83 ENST00000373588.4
NR5A1
nuclear receptor subfamily 5, group A, member 1
chr4_+_154387480 1.82 ENST00000409663.3
ENST00000440693.1
ENST00000409959.3
KIAA0922
KIAA0922
chr1_-_204121298 1.81 ENST00000367199.2
ETNK2
ethanolamine kinase 2
chr12_+_54378923 1.81 ENST00000303460.4
HOXC10
homeobox C10
chr12_+_53817633 1.79 ENST00000257863.4
ENST00000550311.1
ENST00000379791.3
AMHR2
anti-Mullerian hormone receptor, type II
chr1_-_150208498 1.78 ENST00000314136.8
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr17_-_36105009 1.77 ENST00000560016.1
ENST00000427275.2
ENST00000561193.1
HNF1B
HNF1 homeobox B
chr15_-_56535464 1.77 ENST00000559447.2
ENST00000422057.1
ENST00000317318.6
ENST00000423270.1
RFX7
regulatory factor X, 7
chr1_+_212458834 1.77 ENST00000261461.2
PPP2R5A
protein phosphatase 2, regulatory subunit B', alpha
chr13_-_52026730 1.77 ENST00000420668.2
INTS6
integrator complex subunit 6
chr3_+_154797877 1.75 ENST00000462745.1
ENST00000493237.1
MME
membrane metallo-endopeptidase
chr6_+_42749759 1.74 ENST00000314073.5
GLTSCR1L
GLTSCR1-like
chr15_-_41408339 1.74 ENST00000401393.3
INO80
INO80 complex subunit
chr1_-_204121102 1.72 ENST00000367202.4
ETNK2
ethanolamine kinase 2
chr10_+_21823079 1.71 ENST00000377100.3
ENST00000377072.3
ENST00000446906.2
MLLT10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr8_-_57123815 1.69 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
PLAG1
pleiomorphic adenoma gene 1
chr2_+_219264466 1.69 ENST00000273062.2
CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr12_+_53773944 1.68 ENST00000551969.1
ENST00000327443.4
SP1
Sp1 transcription factor
chr2_+_111878483 1.67 ENST00000308659.8
ENST00000357757.2
ENST00000393253.2
ENST00000337565.5
ENST00000393256.3
BCL2L11
BCL2-like 11 (apoptosis facilitator)
chr12_+_53846594 1.66 ENST00000550192.1
PCBP2
poly(rC) binding protein 2
chr8_-_101734170 1.66 ENST00000522387.1
ENST00000518196.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr17_-_42297092 1.65 ENST00000393606.3
UBTF
upstream binding transcription factor, RNA polymerase I
chr6_+_45390222 1.65 ENST00000359524.5
RUNX2
runt-related transcription factor 2
chr19_+_35759824 1.65 ENST00000343550.5
USF2
upstream transcription factor 2, c-fos interacting
chr7_-_27142290 1.65 ENST00000222718.5
HOXA2
homeobox A2
chr12_+_53818855 1.64 ENST00000550839.1
AMHR2
anti-Mullerian hormone receptor, type II
chr1_-_27930102 1.64 ENST00000247087.5
ENST00000374011.2
AHDC1
AT hook, DNA binding motif, containing 1
chr2_-_161349909 1.63 ENST00000392753.3
RBMS1
RNA binding motif, single stranded interacting protein 1
chr2_+_181845532 1.62 ENST00000602475.1
UBE2E3
ubiquitin-conjugating enzyme E2E 3
chr1_+_26737292 1.61 ENST00000254231.4
LIN28A
lin-28 homolog A (C. elegans)
chr18_+_55102917 1.57 ENST00000491143.2
ONECUT2
one cut homeobox 2
chr5_+_36876833 1.57 ENST00000282516.8
ENST00000448238.2
NIPBL
Nipped-B homolog (Drosophila)
chr12_+_122064673 1.57 ENST00000537188.1
ORAI1
ORAI calcium release-activated calcium modulator 1
chr2_+_181845763 1.54 ENST00000602499.1
UBE2E3
ubiquitin-conjugating enzyme E2E 3
chr1_-_111746966 1.53 ENST00000369752.5
DENND2D
DENN/MADD domain containing 2D
chr17_+_38497640 1.52 ENST00000394086.3
RARA
retinoic acid receptor, alpha
chr3_+_154797636 1.50 ENST00000481828.1
MME
membrane metallo-endopeptidase
chr7_+_106809406 1.47 ENST00000468410.1
ENST00000478930.1
ENST00000464009.1
ENST00000222574.4
HBP1
HMG-box transcription factor 1
chr6_+_37787704 1.47 ENST00000474522.1
ZFAND3
zinc finger, AN1-type domain 3
chr19_-_14201776 1.45 ENST00000269724.5
SAMD1
sterile alpha motif domain containing 1
chr2_+_181845843 1.45 ENST00000602710.1
UBE2E3
ubiquitin-conjugating enzyme E2E 3
chr17_+_37618257 1.44 ENST00000447079.4
CDK12
cyclin-dependent kinase 12
chr16_-_4323015 1.44 ENST00000204517.6
TFAP4
transcription factor AP-4 (activating enhancer binding protein 4)
chr19_+_45754505 1.44 ENST00000262891.4
ENST00000300843.4
MARK4
MAP/microtubule affinity-regulating kinase 4
chr3_-_18466026 1.44 ENST00000417717.2
SATB1
SATB homeobox 1
chr7_+_100318423 1.43 ENST00000252723.2
EPO
erythropoietin
chr1_-_53019059 1.43 ENST00000484723.2
ENST00000524582.1
ZCCHC11
zinc finger, CCHC domain containing 11
chr7_-_127672146 1.42 ENST00000476782.1
LRRC4
leucine rich repeat containing 4
chr1_-_204121013 1.42 ENST00000367201.3
ETNK2
ethanolamine kinase 2
chr5_-_142784101 1.42 ENST00000503201.1
ENST00000502892.1
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr1_-_53018654 1.41 ENST00000257177.4
ENST00000355809.4
ENST00000528642.1
ENST00000470626.1
ENST00000371544.3
ZCCHC11
zinc finger, CCHC domain containing 11
chr6_-_44095183 1.40 ENST00000372014.3
MRPL14
mitochondrial ribosomal protein L14
chr12_-_54813229 1.40 ENST00000293379.4
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr17_+_36858694 1.39 ENST00000563897.1
CTB-58E17.1
CTB-58E17.1
chr1_-_151431674 1.39 ENST00000531094.1
POGZ
pogo transposable element with ZNF domain
chr1_+_27022485 1.39 ENST00000324856.7
ARID1A
AT rich interactive domain 1A (SWI-like)
chr10_+_21823243 1.39 ENST00000307729.7
ENST00000377091.2
MLLT10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr17_-_27277615 1.36 ENST00000583747.1
ENST00000584236.1
PHF12
PHD finger protein 12
chr1_+_147013182 1.35 ENST00000234739.3
BCL9
B-cell CLL/lymphoma 9
chr17_+_1646130 1.34 ENST00000453066.1
ENST00000324015.3
ENST00000450523.2
ENST00000453723.1
ENST00000382061.4
SERPINF2
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr17_+_46132037 1.33 ENST00000582155.1
ENST00000583378.1
ENST00000536222.1
NFE2L1
nuclear factor, erythroid 2-like 1
chr20_+_57466357 1.33 ENST00000371095.3
ENST00000371085.3
ENST00000354359.7
ENST00000265620.7
GNAS
GNAS complex locus
chr16_+_30969055 1.33 ENST00000452917.1
SETD1A
SET domain containing 1A
chr1_-_167906277 1.33 ENST00000271373.4
MPC2
mitochondrial pyruvate carrier 2
chr1_-_21503337 1.32 ENST00000400422.1
ENST00000602326.1
ENST00000411888.1
ENST00000438975.1
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr19_-_40324767 1.32 ENST00000601972.1
ENST00000430012.2
ENST00000323039.5
ENST00000348817.3
DYRK1B
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr19_+_35759968 1.31 ENST00000222305.3
ENST00000595068.1
ENST00000379134.3
ENST00000594064.1
ENST00000598058.1
USF2
upstream transcription factor 2, c-fos interacting
chr15_-_65477637 1.31 ENST00000300107.3
CLPX
caseinolytic mitochondrial matrix peptidase chaperone subunit
chr17_+_72427477 1.31 ENST00000342648.5
ENST00000481232.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr1_+_178694408 1.30 ENST00000324778.5
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr7_-_105332084 1.30 ENST00000472195.1
ATXN7L1
ataxin 7-like 1
chr11_-_67141640 1.29 ENST00000533438.1
CLCF1
cardiotrophin-like cytokine factor 1
chr1_+_203765437 1.28 ENST00000550078.1
ZBED6
zinc finger, BED-type containing 6
chr19_+_50433476 1.27 ENST00000596658.1
ATF5
activating transcription factor 5
chr17_-_58469687 1.27 ENST00000590133.1
USP32
ubiquitin specific peptidase 32
chr19_-_38916802 1.27 ENST00000587738.1
RASGRP4
RAS guanyl releasing protein 4
chr1_+_27022839 1.27 ENST00000457599.2
ARID1A
AT rich interactive domain 1A (SWI-like)
chr9_-_127269488 1.26 ENST00000455734.1
NR5A1
nuclear receptor subfamily 5, group A, member 1
chr17_-_60885645 1.26 ENST00000544856.2
MARCH10
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr18_+_42260861 1.24 ENST00000282030.5
SETBP1
SET binding protein 1
chr14_-_38064198 1.24 ENST00000250448.2
FOXA1
forkhead box A1
chr12_-_57505121 1.24 ENST00000538913.2
ENST00000537215.2
ENST00000454075.3
ENST00000554825.1
ENST00000553275.1
ENST00000300134.3
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr19_-_14201507 1.23 ENST00000533683.2
SAMD1
sterile alpha motif domain containing 1
chr15_+_101142722 1.22 ENST00000332783.7
ENST00000558747.1
ENST00000343276.4
ASB7
ankyrin repeat and SOCS box containing 7
chr17_+_54671047 1.22 ENST00000332822.4
NOG
noggin
chr2_-_48132924 1.22 ENST00000403359.3
FBXO11
F-box protein 11
chr12_-_57644952 1.22 ENST00000554578.1
ENST00000546246.2
ENST00000553489.1
ENST00000332782.2
STAC3
SH3 and cysteine rich domain 3
chr17_+_43239231 1.21 ENST00000591576.1
ENST00000591070.1
ENST00000592695.1
HEXIM2
hexamethylene bis-acetamide inducible 2
chrX_-_142722897 1.20 ENST00000338017.4
SLITRK4
SLIT and NTRK-like family, member 4
chr2_-_220117867 1.20 ENST00000456818.1
ENST00000447205.1
TUBA4A
tubulin, alpha 4a
chr17_+_38278530 1.18 ENST00000398532.4
MSL1
male-specific lethal 1 homolog (Drosophila)
chr3_+_88108381 1.18 ENST00000473136.1
RP11-159G9.5
Uncharacterized protein
chr17_-_60885659 1.18 ENST00000311269.5
MARCH10
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chr1_-_211752073 1.18 ENST00000367001.4
SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr1_-_151431647 1.17 ENST00000368863.2
ENST00000409503.1
ENST00000491586.1
ENST00000533351.1
ENST00000540984.1
POGZ
pogo transposable element with ZNF domain
chr17_-_60885700 1.17 ENST00000583600.1
MARCH10
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase
chrX_-_129244454 1.16 ENST00000308167.5
ELF4
E74-like factor 4 (ets domain transcription factor)
chr3_+_5020801 1.15 ENST00000256495.3
BHLHE40
basic helix-loop-helix family, member e40
chr4_+_38665810 1.14 ENST00000261438.5
ENST00000514033.1
KLF3
Kruppel-like factor 3 (basic)
chr12_-_6716569 1.14 ENST00000544040.1
ENST00000545942.1
CHD4
chromodomain helicase DNA binding protein 4
chr6_+_31620191 1.14 ENST00000375918.2
ENST00000375920.4
APOM
apolipoprotein M
chr5_-_56247935 1.13 ENST00000381199.3
ENST00000381226.3
ENST00000381213.3
MIER3
mesoderm induction early response 1, family member 3
chr19_-_38916822 1.13 ENST00000586305.1
RASGRP4
RAS guanyl releasing protein 4
chr12_-_6716534 1.13 ENST00000544484.1
ENST00000309577.6
ENST00000357008.2
CHD4
chromodomain helicase DNA binding protein 4
chr11_-_67980744 1.13 ENST00000401547.2
ENST00000453170.1
ENST00000304363.4
SUV420H1
suppressor of variegation 4-20 homolog 1 (Drosophila)
chr1_+_155036204 1.12 ENST00000368409.3
ENST00000359751.4
ENST00000427683.2
ENST00000556931.1
ENST00000505139.1
EFNA4
EFNA3
EFNA3
ephrin-A4
ephrin-A3
Ephrin-A3; Uncharacterized protein; cDNA FLJ57652, highly similar to Ephrin-A3
chr15_+_91411810 1.11 ENST00000268171.3
FURIN
furin (paired basic amino acid cleaving enzyme)
chr1_+_178694362 1.11 ENST00000367634.2
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr1_+_178694300 1.11 ENST00000367635.3
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr17_-_56065484 1.11 ENST00000581208.1
VEZF1
vascular endothelial zinc finger 1
chr11_-_72493574 1.10 ENST00000536290.1
STARD10
StAR-related lipid transfer (START) domain containing 10
chr3_-_53080047 1.10 ENST00000482396.1
ENST00000358080.2
ENST00000296295.6
ENST00000394752.3
SFMBT1
Scm-like with four mbt domains 1
chr8_-_101734308 1.10 ENST00000519004.1
ENST00000519363.1
ENST00000520142.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr12_+_57522258 1.10 ENST00000553277.1
ENST00000243077.3
LRP1
low density lipoprotein receptor-related protein 1
chr17_-_7154984 1.10 ENST00000574322.1
CTDNEP1
CTD nuclear envelope phosphatase 1
chr6_-_31763276 1.09 ENST00000440048.1
VARS
valyl-tRNA synthetase
chrX_-_129244655 1.09 ENST00000335997.7
ELF4
E74-like factor 4 (ets domain transcription factor)
chr13_+_20532900 1.08 ENST00000382871.2
ZMYM2
zinc finger, MYM-type 2
chr6_+_18155560 1.08 ENST00000546309.2
ENST00000388870.2
ENST00000397244.1
KDM1B
lysine (K)-specific demethylase 1B
chr17_+_7477040 1.07 ENST00000581384.1
ENST00000577929.1
EIF4A1
eukaryotic translation initiation factor 4A1
chr1_-_149908217 1.06 ENST00000369140.3
MTMR11
myotubularin related protein 11
chr1_-_150208320 1.06 ENST00000534220.1
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr15_-_80215984 1.06 ENST00000485386.1
ENST00000479961.1
ST20
ST20-MTHFS
suppressor of tumorigenicity 20
ST20-MTHFS readthrough
chr19_-_17356697 1.05 ENST00000291442.3
NR2F6
nuclear receptor subfamily 2, group F, member 6
chr7_-_149470540 1.05 ENST00000302017.3
ZNF467
zinc finger protein 467
chr22_+_41487711 1.05 ENST00000263253.7
EP300
E1A binding protein p300
chr18_+_21594585 1.04 ENST00000317571.3
TTC39C
tetratricopeptide repeat domain 39C
chrX_+_123095860 1.04 ENST00000428941.1
STAG2
stromal antigen 2
chr2_+_45168875 1.04 ENST00000260653.3
SIX3
SIX homeobox 3
chr1_+_26856236 1.03 ENST00000374168.2
ENST00000374166.4
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.6 GO:0045013 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
1.0 3.0 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
1.0 1.0 GO:0021571 rhombomere 5 development(GO:0021571)
1.0 2.9 GO:0061386 closure of optic fissure(GO:0061386)
0.9 4.4 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.8 0.8 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.8 0.8 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.8 3.1 GO:0060032 notochord regression(GO:0060032)
0.8 3.8 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.7 2.0 GO:0097254 renal tubular secretion(GO:0097254)
0.6 3.1 GO:0007538 primary sex determination(GO:0007538)
0.6 1.8 GO:1904772 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.6 3.0 GO:0000430 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.6 5.9 GO:0007256 activation of JNKK activity(GO:0007256)
0.6 8.7 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.6 3.4 GO:0001880 Mullerian duct regression(GO:0001880)
0.6 2.2 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.6 1.7 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.5 1.6 GO:0035283 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.5 2.7 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.5 3.8 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.5 2.1 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.5 1.6 GO:0061010 external genitalia morphogenesis(GO:0035261) gall bladder development(GO:0061010)
0.5 5.7 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.5 5.2 GO:0010587 miRNA catabolic process(GO:0010587)
0.5 1.9 GO:0035565 regulation of pronephros size(GO:0035565)
0.5 1.4 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.5 1.4 GO:0072361 regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361)
0.5 1.8 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.5 1.8 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.4 3.6 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.4 1.3 GO:0014908 myotube differentiation involved in skeletal muscle regeneration(GO:0014908)
0.4 1.7 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.4 1.2 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.4 3.7 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.4 1.2 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.4 1.2 GO:0042668 auditory receptor cell fate determination(GO:0042668)
0.4 3.0 GO:0036166 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.4 1.1 GO:0032904 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.4 4.7 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.3 1.0 GO:0009946 proximal/distal axis specification(GO:0009946)
0.3 1.3 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.3 1.7 GO:0070384 growth plate cartilage chondrocyte growth(GO:0003430) Harderian gland development(GO:0070384)
0.3 2.6 GO:0044334 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.3 4.9 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.3 1.3 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.3 0.6 GO:0060796 regulation of transcription involved in primary germ layer cell fate commitment(GO:0060796)
0.3 4.0 GO:0003149 membranous septum morphogenesis(GO:0003149)
0.3 1.5 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.3 3.3 GO:0071492 cellular response to UV-A(GO:0071492)
0.3 5.3 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.3 2.9 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.3 1.1 GO:0034444 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.3 3.9 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.3 5.6 GO:0007379 segment specification(GO:0007379)
0.3 2.7 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.3 2.1 GO:0060136 enucleate erythrocyte differentiation(GO:0043353) embryonic process involved in female pregnancy(GO:0060136)
0.3 0.5 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.3 2.3 GO:0097324 melanocyte migration(GO:0097324) positive regulation of lens fiber cell differentiation(GO:1902748)
0.3 1.8 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.3 1.0 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.3 0.8 GO:0043633 polyadenylation-dependent RNA catabolic process(GO:0043633) polyadenylation-dependent ncRNA catabolic process(GO:0043634)
0.3 0.8 GO:0001172 transcription, RNA-templated(GO:0001172)
0.2 1.0 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.2 0.7 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.2 2.2 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.2 1.2 GO:0061687 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.2 1.2 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.2 0.9 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.2 2.8 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.2 0.9 GO:0098582 innate vocalization behavior(GO:0098582)
0.2 1.3 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.2 0.7 GO:0048627 myoblast development(GO:0048627)
0.2 3.1 GO:0072718 response to cisplatin(GO:0072718)
0.2 2.9 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.2 3.3 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.2 2.6 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.2 0.9 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.2 1.7 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.2 0.6 GO:1990108 protein linear deubiquitination(GO:1990108)
0.2 1.4 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.2 2.2 GO:0072553 terminal button organization(GO:0072553)
0.2 0.8 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.2 3.9 GO:0021924 cell proliferation in external granule layer(GO:0021924) cerebellar granule cell precursor proliferation(GO:0021930)
0.2 0.8 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.2 1.3 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.2 2.3 GO:0001866 NK T cell proliferation(GO:0001866)
0.2 1.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.2 4.1 GO:0051382 kinetochore assembly(GO:0051382)
0.2 2.2 GO:0021759 globus pallidus development(GO:0021759)
0.2 0.5 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.2 3.3 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.2 1.1 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.2 0.9 GO:0090467 L-arginine import(GO:0043091) arginine import(GO:0090467)
0.2 0.4 GO:0090107 regulation of high-density lipoprotein particle assembly(GO:0090107)
0.2 0.5 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.2 1.0 GO:1902617 response to fluoride(GO:1902617)
0.2 0.7 GO:0051413 response to cortisone(GO:0051413)
0.2 1.8 GO:0002051 osteoblast fate commitment(GO:0002051)
0.2 0.8 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.2 6.5 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736)
0.2 1.9 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.2 1.7 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.2 5.0 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.2 1.4 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.2 1.1 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.2 0.9 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.6 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.1 4.3 GO:0016180 snRNA processing(GO:0016180)
0.1 5.4 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 0.4 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.1 0.6 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.8 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.1 3.7 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 0.5 GO:0060023 soft palate development(GO:0060023)
0.1 0.4 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.1 0.4 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 1.3 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1 0.9 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.1 0.3 GO:1902534 single-organism membrane invagination(GO:1902534)
0.1 0.5 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.7 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.1 0.6 GO:0060684 epithelial-mesenchymal cell signaling(GO:0060684)
0.1 1.1 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.1 1.7 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.4 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.1 2.2 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 3.6 GO:0021516 dorsal spinal cord development(GO:0021516)
0.1 1.3 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 1.7 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 1.4 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.1 0.3 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.1 0.3 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.2 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.1 0.5 GO:0031291 mitotic chromosome movement towards spindle pole(GO:0007079) Ran protein signal transduction(GO:0031291)
0.1 0.8 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.9 GO:0070885 positive regulation of sodium:proton antiporter activity(GO:0032417) negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.1 1.7 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.1 1.0 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 0.5 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986) oncogene-induced cell senescence(GO:0090402)
0.1 2.2 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.1 0.4 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
0.1 0.5 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 1.1 GO:0002084 protein depalmitoylation(GO:0002084)
0.1 0.8 GO:0031507 heterochromatin assembly(GO:0031507)
0.1 0.9 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 5.7 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.1 0.5 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.1 0.4 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.1 0.2 GO:0043974 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.1 1.8 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.4 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.1 4.9 GO:0043486 histone exchange(GO:0043486)
0.1 0.2 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.1 1.0 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 15.2 GO:0016575 histone deacetylation(GO:0016575)
0.1 0.3 GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
0.1 0.4 GO:0035262 gonad morphogenesis(GO:0035262)
0.1 0.6 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 1.9 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1 0.3 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
0.1 0.5 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.1 0.9 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 1.1 GO:0032782 bile acid secretion(GO:0032782)
0.1 0.7 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.1 2.3 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.9 GO:1902961 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.1 0.3 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.1 0.6 GO:0002042 cell migration involved in sprouting angiogenesis(GO:0002042)
0.1 0.4 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.1 0.5 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.1 1.2 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.1 1.7 GO:0035246 peptidyl-arginine N-methylation(GO:0035246)
0.1 0.3 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 2.0 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 0.4 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.1 0.4 GO:0051661 maintenance of centrosome location(GO:0051661)
0.1 0.9 GO:2000370 positive regulation of clathrin-mediated endocytosis(GO:2000370)
0.1 0.3 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.1 1.3 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.1 1.9 GO:0032486 Rap protein signal transduction(GO:0032486)
0.1 1.6 GO:0002115 store-operated calcium entry(GO:0002115)
0.1 0.9 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.8 GO:0007000 nucleolus organization(GO:0007000)
0.1 0.3 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 0.2 GO:0044805 late nucleophagy(GO:0044805)
0.1 0.9 GO:0019388 galactose catabolic process(GO:0019388)
0.1 0.7 GO:1905049 negative regulation of metallopeptidase activity(GO:1905049)
0.1 0.2 GO:0071529 cementum mineralization(GO:0071529)
0.1 3.1 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.1 1.7 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 0.4 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 0.3 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.1 1.6 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 0.5 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.1 0.4 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.1 3.8 GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423)
0.1 1.7 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.1 0.5 GO:0071484 cellular response to light intensity(GO:0071484)
0.1 0.1 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.1 0.8 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 0.6 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.2 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 0.6 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.1 2.4 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.1 0.8 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.1 1.5 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.1 0.7 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 1.8 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.1 0.3 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.1 0.5 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 0.2 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.1 2.9 GO:0006270 DNA replication initiation(GO:0006270)
0.1 0.2 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.1 1.1 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.1 0.3 GO:0030047 actin modification(GO:0030047)
0.1 3.3 GO:0007520 myoblast fusion(GO:0007520)
0.1 0.3 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.2 GO:0051796 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
0.0 0.3 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.0 1.0 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.3 GO:0051510 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.5 GO:0051013 microtubule severing(GO:0051013)
0.0 0.6 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.4 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.8 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0 0.5 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.3 GO:0019827 stem cell population maintenance(GO:0019827)
0.0 0.2 GO:1903281 positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.0 1.0 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.6 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.4 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.0 0.5 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.0 0.1 GO:0051384 response to glucocorticoid(GO:0051384)
0.0 0.3 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.0 1.6 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.3 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.7 GO:0031268 pseudopodium organization(GO:0031268)
0.0 0.2 GO:0072752 cellular response to rapamycin(GO:0072752)
0.0 0.8 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.8 GO:0042921 glucocorticoid receptor signaling pathway(GO:0042921)
0.0 0.4 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 1.4 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.0 1.1 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 1.0 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.5 GO:0015732 prostaglandin transport(GO:0015732)
0.0 0.0 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
0.0 2.5 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.9 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.3 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 1.1 GO:0039702 viral budding via host ESCRT complex(GO:0039702)
0.0 0.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.2 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.7 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.4 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 4.5 GO:0016573 histone acetylation(GO:0016573)
0.0 0.7 GO:0051291 protein heterooligomerization(GO:0051291)
0.0 0.9 GO:0016574 histone ubiquitination(GO:0016574)
0.0 0.2 GO:0061760 antifungal innate immune response(GO:0061760)
0.0 0.3 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.6 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.3 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.0 0.7 GO:0007351 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.2 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 2.6 GO:0006968 cellular defense response(GO:0006968)
0.0 0.3 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.3 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 2.3 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.0 0.3 GO:0045656 negative regulation of monocyte differentiation(GO:0045656)
0.0 0.4 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.8 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.7 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.0 0.6 GO:0036344 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.0 0.3 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.4 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.3 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.4 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.3 GO:0007512 adult heart development(GO:0007512)
0.0 2.5 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.6 GO:1902186 regulation of viral release from host cell(GO:1902186)
0.0 0.8 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.4 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.3 GO:0032196 transposition(GO:0032196)
0.0 0.1 GO:0071422 succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422)
0.0 0.4 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 2.2 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.2 GO:0030575 nuclear body organization(GO:0030575)
0.0 0.4 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.2 GO:0010626 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.0 0.4 GO:0034205 beta-amyloid formation(GO:0034205)
0.0 0.2 GO:0055048 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.0 0.5 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.6 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.0 0.6 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.6 GO:1903831 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 3.6 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 1.3 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 1.7 GO:0030049 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.1 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 1.2 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.5 GO:0002335 mature B cell differentiation(GO:0002335)
0.0 0.6 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.0 0.1 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0 0.3 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.6 GO:0021904 dorsal/ventral neural tube patterning(GO:0021904)
0.0 0.8 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.9 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.5 GO:0090383 phagosome acidification(GO:0090383)
0.0 1.7 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 4.6 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.2 GO:0042048 olfactory behavior(GO:0042048)
0.0 0.3 GO:0097435 fibril organization(GO:0097435)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.3 GO:0048741 skeletal muscle fiber development(GO:0048741)
0.0 0.9 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.7 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 1.4 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.2 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.5 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.0 0.2 GO:0014029 neural crest formation(GO:0014029)
0.0 1.6 GO:1902017 regulation of cilium assembly(GO:1902017)
0.0 2.3 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.0 0.1 GO:0030497 fatty acid elongation(GO:0030497)
0.0 0.0 GO:0015770 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 0.3 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 0.5 GO:0072348 sulfur compound transport(GO:0072348)
0.0 0.4 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.1 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.5 5.3 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.4 1.3 GO:0005940 septin ring(GO:0005940) septin collar(GO:0032173)
0.4 11.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.4 2.4 GO:0008537 proteasome activator complex(GO:0008537)
0.4 4.9 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.4 1.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.4 1.8 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.3 1.4 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.3 2.6 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.3 5.4 GO:0000812 Swr1 complex(GO:0000812)
0.3 1.9 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.3 3.8 GO:0072487 MSL complex(GO:0072487)
0.3 1.8 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.3 3.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.3 3.8 GO:0005642 annulate lamellae(GO:0005642)
0.3 4.3 GO:0032039 integrator complex(GO:0032039)
0.3 1.3 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.2 0.7 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.2 1.5 GO:0031501 mannosyltransferase complex(GO:0031501)
0.2 0.8 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.2 5.5 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.2 2.9 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.2 0.5 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.2 12.5 GO:1990391 DNA repair complex(GO:1990391)
0.2 0.8 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.2 0.6 GO:0042585 germinal vesicle(GO:0042585)
0.2 1.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 4.0 GO:0071564 npBAF complex(GO:0071564)
0.1 2.9 GO:0045120 pronucleus(GO:0045120)
0.1 0.9 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 5.9 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 0.4 GO:0075341 host cell PML body(GO:0075341)
0.1 1.3 GO:0042382 paraspeckles(GO:0042382)
0.1 1.7 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 1.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 3.1 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 1.3 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 1.2 GO:0033503 HULC complex(GO:0033503)
0.1 1.0 GO:0005827 polar microtubule(GO:0005827)
0.1 1.4 GO:0005577 fibrinogen complex(GO:0005577)
0.1 3.5 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 1.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 3.3 GO:0005721 pericentric heterochromatin(GO:0005721)
0.1 0.8 GO:0035102 PRC1 complex(GO:0035102)
0.1 9.7 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 6.0 GO:0005844 polysome(GO:0005844)
0.1 4.7 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 0.8 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.3 GO:0000125 PCAF complex(GO:0000125)
0.1 2.0 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 1.4 GO:0016461 unconventional myosin complex(GO:0016461)
0.1 2.2 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.1 2.3 GO:0035097 histone methyltransferase complex(GO:0035097)
0.1 1.1 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.7 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 0.5 GO:0035976 AP1 complex(GO:0035976)
0.1 0.4 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 1.1 GO:0005916 fascia adherens(GO:0005916)
0.1 0.8 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 0.6 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 4.6 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 1.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 3.1 GO:0097546 ciliary base(GO:0097546)
0.1 0.6 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 8.3 GO:0016605 PML body(GO:0016605)
0.0 2.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.4 GO:0044194 cytolytic granule(GO:0044194)
0.0 25.7 GO:0000785 chromatin(GO:0000785)
0.0 1.0 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.3 GO:0000346 transcription export complex(GO:0000346)
0.0 0.5 GO:0005638 lamin filament(GO:0005638)
0.0 0.5 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.8 GO:0000974 Prp19 complex(GO:0000974)
0.0 5.9 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.6 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 2.0 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 5.8 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.3 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 1.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.5 GO:0010369 chromocenter(GO:0010369)
0.0 0.6 GO:0005818 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 0.8 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.5 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 1.1 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.5 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.8 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.7 GO:0031143 pseudopodium(GO:0031143)
0.0 9.4 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 22.9 GO:0016604 nuclear body(GO:0016604)
0.0 0.9 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.9 GO:0035371 microtubule plus-end(GO:0035371)
0.0 1.7 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.6 GO:0031519 PcG protein complex(GO:0031519)
0.0 1.4 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 0.2 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 87.8 GO:0005654 nucleoplasm(GO:0005654)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.6 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 2.1 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 2.3 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.5 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 0.0 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 5.1 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.7 GO:0005643 nuclear pore(GO:0005643)
0.0 0.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.4 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.4 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.4 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 1.5 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.9 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 2.2 GO:0005903 brush border(GO:0005903)
0.0 0.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.3 GO:0031093 platelet alpha granule lumen(GO:0031093)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
1.0 3.0 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.9 3.4 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.6 4.8 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.5 1.5 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.5 1.4 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.5 2.8 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.5 1.9 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.5 1.8 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.5 5.0 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.4 3.7 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.4 1.6 GO:0036033 mediator complex binding(GO:0036033)
0.4 3.3 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.4 9.0 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.4 1.1 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.3 1.0 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.3 1.0 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.3 8.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.3 2.4 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.3 2.2 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.3 10.6 GO:0070410 co-SMAD binding(GO:0070410)
0.3 2.4 GO:0061133 endopeptidase activator activity(GO:0061133)
0.3 0.8 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.2 1.2 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.2 2.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.2 1.9 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.2 5.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2 2.6 GO:0008142 oxysterol binding(GO:0008142)
0.2 22.4 GO:0004407 histone deacetylase activity(GO:0004407)
0.2 0.9 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.2 1.7 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.2 8.0 GO:0008266 poly(U) RNA binding(GO:0008266)
0.2 2.1 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.2 1.8 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.2 1.0 GO:0031208 POZ domain binding(GO:0031208)
0.2 2.2 GO:0051525 NFAT protein binding(GO:0051525)
0.2 2.5 GO:0008420 CTD phosphatase activity(GO:0008420)
0.2 3.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.2 1.1 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.2 0.5 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.2 2.6 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.2 2.3 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.2 3.8 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.2 1.3 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.2 3.2 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.2 1.8 GO:1990226 histone methyltransferase binding(GO:1990226)
0.2 0.8 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 1.0 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.6 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.7 GO:0019770 IgG receptor activity(GO:0019770)
0.1 8.9 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 2.9 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 1.9 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1 0.4 GO:0045142 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) DNA/RNA helicase activity(GO:0033677) triplex DNA binding(GO:0045142)
0.1 1.0 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.9 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 7.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 0.9 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.4 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.1 1.0 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 0.6 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.1 1.5 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 2.0 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.8 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 2.9 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 1.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 2.9 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 4.8 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 3.2 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 0.4 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 1.6 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.1 1.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 2.2 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1 16.5 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.1 0.5 GO:0003883 CTP synthase activity(GO:0003883)
0.1 0.3 GO:0070984 SET domain binding(GO:0070984)
0.1 3.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 1.3 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 2.7 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 0.4 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.1 1.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 3.8 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 0.3 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 0.4 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.1 0.4 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.1 7.2 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 1.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 1.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.3 GO:0004803 transposase activity(GO:0004803)
0.1 2.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.5 GO:0050436 microfibril binding(GO:0050436)
0.1 0.9 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 1.1 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 1.7 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.1 6.3 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 1.7 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 0.2 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 2.7 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 4.7 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 2.0 GO:0000339 RNA cap binding(GO:0000339)
0.1 0.3 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 1.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 53.7 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.1 0.7 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.2 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.1 2.6 GO:0070840 dynein complex binding(GO:0070840)
0.1 0.5 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.1 7.2 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1 1.0 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 0.4 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.1 3.2 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 11.8 GO:0042393 histone binding(GO:0042393)
0.1 0.4 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.1 1.3 GO:0015643 toxic substance binding(GO:0015643) proteasome binding(GO:0070628)
0.1 0.9 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.4 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 1.4 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.5 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.3 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.5 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.3 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.8 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.7 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 4.1 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.4 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.6 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.7 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 5.1 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.7 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.4 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.5 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 1.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.3 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.4 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.5 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 1.3 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 1.2 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.5 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.7 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 2.4 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 1.1 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.7 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.8 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.3 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.0 0.3 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.3 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.5 GO:0098847 sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.3 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0017153 succinate transmembrane transporter activity(GO:0015141) sodium:dicarboxylate symporter activity(GO:0017153)
0.0 6.8 GO:0003682 chromatin binding(GO:0003682)
0.0 1.6 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.7 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.3 GO:0043559 insulin binding(GO:0043559)
0.0 0.1 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.3 GO:0045159 myosin II binding(GO:0045159)
0.0 0.9 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.5 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.7 GO:0017166 vinculin binding(GO:0017166)
0.0 2.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 1.4 GO:0003684 damaged DNA binding(GO:0003684)
0.0 1.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.9 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 2.0 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.5 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.4 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.3 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.2 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.0 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.0 0.3 GO:0003700 transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.6 GO:0050699 WW domain binding(GO:0050699)
0.0 1.2 GO:0004386 helicase activity(GO:0004386)
0.0 0.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051) collagen V binding(GO:0070052)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.0 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.5 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0005113 patched binding(GO:0005113)
0.0 2.0 GO:0002020 protease binding(GO:0002020)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 18.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.2 3.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 8.4 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.1 8.3 PID BMP PATHWAY BMP receptor signaling
0.1 2.9 PID MYC PATHWAY C-MYC pathway
0.1 2.3 PID ALK2 PATHWAY ALK2 signaling events
0.1 6.6 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 2.4 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 14.6 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 11.2 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 13.7 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 3.2 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 1.7 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 1.3 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 0.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 3.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 10.4 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 1.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 1.5 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 3.1 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 3.5 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 3.5 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 3.7 PID RAS PATHWAY Regulation of Ras family activation
0.1 4.9 PID PLK1 PATHWAY PLK1 signaling events
0.1 0.8 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 5.6 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.1 2.9 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 3.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 3.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 2.2 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.1 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 2.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.0 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.0 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.6 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.4 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 2.1 PID TNF PATHWAY TNF receptor signaling pathway
0.0 2.2 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.6 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.6 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.1 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 2.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.7 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.6 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.3 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.4 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.4 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 1.1 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.5 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.3 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.4 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.8 PID ATM PATHWAY ATM pathway
0.0 0.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.8 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.0 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.3 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.3 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.7 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.3 PID NCADHERIN PATHWAY N-cadherin signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 0.6 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.3 7.7 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.3 3.8 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.3 3.8 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.3 15.5 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.2 4.7 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 5.8 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 4.7 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 3.5 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 4.6 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.1 1.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 6.8 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 2.5 REACTOME RNA POL I TRANSCRIPTION Genes involved in RNA Polymerase I Transcription
0.1 10.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 3.3 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.1 2.1 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 2.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 1.6 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 5.5 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 2.2 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 2.5 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 1.0 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 1.1 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.1 3.2 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 2.0 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 1.1 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 0.5 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 1.4 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.1 0.4 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 2.8 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 4.5 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.1 2.0 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1 1.1 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 16.9 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 2.7 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 1.5 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.9 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.0 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 5.1 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 2.1 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 2.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 3.0 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 4.6 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.7 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 4.9 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 3.4 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 5.6 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.4 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.3 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0 0.3 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.9 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 1.1 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.5 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.9 REACTOME KERATAN SULFATE KERATIN METABOLISM Genes involved in Keratan sulfate/keratin metabolism
0.0 1.8 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.4 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 1.7 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 1.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.4 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.8 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.5 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.5 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.6 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.4 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.2 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 1.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell