Project
Illumina Body Map 2: averaged replicates
Navigation
Downloads
Results for ZNF740_ZNF219
Z-value: 2.34
Motif logo
Transcription factors associated with ZNF740_ZNF219
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ZNF219 | hg19_v2_chr14_-_21562671_21562702 | -0.45 | 1.1e-02 | Click! |
| ZNF740 | hg19_v2_chr12_+_53574464_53574539 | -0.04 | 8.1e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of ZNF740_ZNF219
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 15.2 | GO:0016575 | histone deacetylation(GO:0016575) |
| 0.6 | 8.7 | GO:0002191 | cap-dependent translational initiation(GO:0002191) |
| 0.2 | 6.5 | GO:0045736 | negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) |
| 0.6 | 5.9 | GO:0007256 | activation of JNKK activity(GO:0007256) |
| 0.5 | 5.7 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 0.1 | 5.7 | GO:0070534 | protein K63-linked ubiquitination(GO:0070534) |
| 1.4 | 5.6 | GO:0045013 | carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) |
| 0.3 | 5.6 | GO:0007379 | segment specification(GO:0007379) |
| 0.1 | 5.4 | GO:0043984 | histone H4-K16 acetylation(GO:0043984) |
| 0.3 | 5.3 | GO:0075522 | IRES-dependent viral translational initiation(GO:0075522) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 87.8 | GO:0005654 | nucleoplasm(GO:0005654) |
| 0.0 | 25.7 | GO:0000785 | chromatin(GO:0000785) |
| 0.0 | 22.9 | GO:0016604 | nuclear body(GO:0016604) |
| 0.2 | 12.5 | GO:1990391 | DNA repair complex(GO:1990391) |
| 0.4 | 11.1 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.1 | 9.7 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.0 | 9.4 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.0 | 8.3 | GO:0016605 | PML body(GO:0016605) |
| 0.1 | 6.0 | GO:0005844 | polysome(GO:0005844) |
| 0.1 | 5.9 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 53.7 | GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012) |
| 0.2 | 22.4 | GO:0004407 | histone deacetylase activity(GO:0004407) |
| 0.1 | 16.5 | GO:0001158 | enhancer sequence-specific DNA binding(GO:0001158) |
| 0.1 | 11.8 | GO:0042393 | histone binding(GO:0042393) |
| 0.3 | 10.6 | GO:0070410 | co-SMAD binding(GO:0070410) |
| 0.4 | 9.0 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.1 | 8.9 | GO:0043425 | bHLH transcription factor binding(GO:0043425) |
| 0.3 | 8.1 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.2 | 8.0 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
| 0.1 | 7.7 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 18.2 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.1 | 14.6 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.1 | 13.7 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.1 | 11.2 | PID HDAC CLASSI PATHWAY | Signaling events mediated by HDAC Class I |
| 0.1 | 10.4 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.1 | 8.4 | SIG IL4RECEPTOR IN B LYPHOCYTES | Genes related to IL4 rceptor signaling in B lymphocytes |
| 0.1 | 8.3 | PID BMP PATHWAY | BMP receptor signaling |
| 0.1 | 6.6 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.1 | 5.6 | PID PTP1B PATHWAY | Signaling events mediated by PTP1B |
| 0.1 | 4.9 | PID PLK1 PATHWAY | PLK1 signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 16.9 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.3 | 15.5 | REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
| 0.1 | 10.4 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.3 | 7.7 | REACTOME MTORC1 MEDIATED SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 0.1 | 6.8 | REACTOME REGULATION OF BETA CELL DEVELOPMENT | Genes involved in Regulation of beta-cell development |
| 0.1 | 5.8 | REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.0 | 5.6 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 0.1 | 5.5 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 0.0 | 5.1 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.0 | 4.9 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |