ISMARA results: AAGUGCU

Project

Illumina Body Map 2

Navigation

Downloads

Results for AAGUGCU

Z-value: 0.63

Motif logo

miRNA associated with seed AAGUGCU

Name	miRBASE accession
hsa-miR-302a-3p miRBase	MIMAT0000684
hsa-miR-302b-3p miRBase	MIMAT0000715
hsa-miR-302c-3p.1 miRBase	MIMAT0000717
hsa-miR-302d-3p miRBase	MIMAT0000718
hsa-miR-302e miRBase	MIMAT0005931
hsa-miR-372-3p miRBase	MIMAT0000724
hsa-miR-373-3p miRBase	MIMAT0000726
hsa-miR-520a-3p miRBase	MIMAT0002834
hsa-miR-520b miRBase	MIMAT0002843
hsa-miR-520c-3p miRBase	MIMAT0002846
hsa-miR-520d-3p miRBase	MIMAT0002856
hsa-miR-520e miRBase	MIMAT0002825

Activity profile of AAGUGCU motif

Sorted Z-values of AAGUGCU motif

Top targets:

Search:

Show entries

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chrX_-_25034065 Show fit	1.88	ENST00000379044.4	ARX Ensembl NCBI GeneCards UniProt NextProt Show fit	aristaless related homeobox
chr3_-_138665969 Show fit	1.49	ENST00000330315.3	FOXL2 Ensembl NCBI GeneCards UniProt NextProt Show fit	forkhead box L2
chr1_-_226129083 Show fit	1.22	ENST00000420304.2	LEFTY2 Ensembl NCBI GeneCards UniProt NextProt Show fit	left-right determination factor 2
chr5_-_114515734 Show fit	1.17	ENST00000514154.1 ENST00000282369.3	TRIM36 Ensembl NCBI GeneCards UniProt NextProt Show fit	tripartite motif containing 36
chr4_-_109089573 Show fit	1.14	ENST00000265165.1	LEF1 Ensembl NCBI GeneCards UniProt NextProt Show fit	lymphoid enhancer-binding factor 1
chr20_+_9494987 Show fit	1.11	ENST00000427562.2 ENST00000246070.2	LAMP5 Ensembl NCBI GeneCards UniProt NextProt Show fit	lysosomal-associated membrane protein family, member 5
chr2_-_166930131 Show fit	1.08	ENST00000303395.4 ENST00000409050.1 ENST00000423058.2 ENST00000375405.3	SCN1A Ensembl NCBI GeneCards UniProt NextProt Show fit	sodium channel, voltage-gated, type I, alpha subunit
chr12_-_45269430 Show fit	1.08	ENST00000395487.2	NELL2 Ensembl NCBI GeneCards UniProt NextProt Show fit	NEL-like 2 (chicken)
chr11_+_129245796 Show fit	0.99	ENST00000281437.4	BARX2 Ensembl NCBI GeneCards UniProt NextProt Show fit	BARX homeobox 2
chr9_-_23821273 Show fit	0.92	ENST00000380110.4	ELAVL2 Ensembl NCBI GeneCards UniProt NextProt Show fit	ELAV like neuron-specific RNA binding protein 2

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of AAGUGCU

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.9	GO:0021831	embryonic olfactory bulb interneuron precursor migration(GO:0021831)
0.3	1.5	GO:0033686	positive regulation of luteinizing hormone secretion(GO:0033686)
0.1	1.2	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0	1.2	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0	1.2	GO:0007340	acrosome reaction(GO:0007340)
0.2	1.1	GO:0061153	trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.1	1.1	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	1.0	GO:0001502	cartilage condensation(GO:0001502)
0.0	1.0	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.3	0.8	GO:0097535	lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)

Showing 1 to 10 of 103 entries

Gene overrepresentation in cellular_component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.6	GO:0045171	intercellular bridge(GO:0045171)
0.1	1.5	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.1	1.1	GO:0032584	growth cone membrane(GO:0032584)
0.1	1.1	GO:1990907	beta-catenin-TCF complex(GO:1990907)
0.0	0.7	GO:0016592	mediator complex(GO:0016592)
0.0	0.6	GO:0032433	filopodium tip(GO:0032433)
0.1	0.4	GO:0035189	Rb-E2F complex(GO:0035189)
0.1	0.4	GO:0033186	CAF-1 complex(GO:0033186)
0.1	0.4	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
0.0	0.4	GO:0005587	collagen type IV trimer(GO:0005587)

Showing 1 to 10 of 28 entries

Gene overrepresentation in molecular_function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.9	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0	1.4	GO:1905030	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1	1.3	GO:0030284	estrogen receptor activity(GO:0030284)
0.0	1.3	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.0	1.3	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.1	0.9	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1	0.8	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.0	0.8	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.1	0.7	GO:0038025	reelin receptor activity(GO:0038025)
0.0	0.7	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)

Showing 1 to 10 of 52 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

Search:

Show entries

Total log-likelihood	Term	Description
1.2	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.8	PID AURORA A PATHWAY	Aurora A signaling
0.7	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.7	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.5	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.4	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.4	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.4	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.3	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.3	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway

Showing 1 to 10 of 11 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.2	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.7	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	0.7	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.7	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	0.6	REACTOME FGFR1 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR1 ligand binding and activation
0.0	0.5	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.1	0.4	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0	0.4	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.3	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.2	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors

Showing 1 to 10 of 10 entries

Results for AAGUGCU

Z-value: 0.63

Motif logo

miRNA associated with seed AAGUGCU

Activity profile of AAGUGCU motif

Sorted Z-values of AAGUGCU motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of AAGUGCU

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: