ISMARA results: AGCAGCA

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Illumina Body Map 2

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Results for AGCAGCA

Z-value: 0.66

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miRNA associated with seed AGCAGCA

Name	miRBASE accession
hsa-miR-15a-5p miRBase	MIMAT0000068
hsa-miR-15b-5p miRBase	MIMAT0000417
hsa-miR-16-5p miRBase	MIMAT0000069
hsa-miR-195-5p miRBase	MIMAT0000461
hsa-miR-424-5p miRBase	MIMAT0001341
hsa-miR-497-5p miRBase	MIMAT0002820
hsa-miR-6838-5p miRBase	MIMAT0027578

Activity profile of AGCAGCA motif

Sorted Z-values of AGCAGCA motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr5_+_42423872 Show fit	2.13	ENST00000230882.4 ENST00000357703.3	GHR Ensembl NCBI GeneCards UniProt NextProt Show fit	growth hormone receptor
chr16_+_56672571 Show fit	1.60	ENST00000290705.8	MT1A Ensembl NCBI GeneCards UniProt NextProt Show fit	metallothionein 1A
chr11_+_113930291 Show fit	1.33	ENST00000335953.4	ZBTB16 Ensembl NCBI GeneCards UniProt NextProt Show fit	zinc finger and BTB domain containing 16
chr7_-_95225768 Show fit	1.22	ENST00000005178.5	PDK4 Ensembl NCBI GeneCards UniProt NextProt Show fit	pyruvate dehydrogenase kinase, isozyme 4
chr11_+_12695944 Show fit	1.21	ENST00000361905.4	TEAD1 Ensembl NCBI GeneCards UniProt NextProt Show fit	TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr6_+_43737939 Show fit	1.17	ENST00000372067.3	VEGFA Ensembl NCBI GeneCards UniProt NextProt Show fit	vascular endothelial growth factor A
chr12_+_109554386 Show fit	1.12	ENST00000338432.7	ACACB Ensembl NCBI GeneCards UniProt NextProt Show fit	acetyl-CoA carboxylase beta
chr8_-_75233563 Show fit	1.02	ENST00000342232.4	JPH1 Ensembl NCBI GeneCards UniProt NextProt Show fit	junctophilin 1
chr18_-_30050395 Show fit	1.02	ENST00000269209.6 ENST00000399218.4	GAREM Ensembl NCBI GeneCards UniProt NextProt Show fit	GRB2 associated, regulator of MAPK1
chr11_+_94501497 Show fit	1.01	ENST00000317829.8 ENST00000317837.9 ENST00000433060.2	AMOTL1 Ensembl NCBI GeneCards UniProt NextProt Show fit	angiomotin like 1

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of AGCAGCA

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.3	2.1	GO:0000255	allantoin metabolic process(GO:0000255)
0.0	1.6	GO:0071294	cellular response to zinc ion(GO:0071294)
0.2	1.3	GO:0051138	positive regulation of NK T cell differentiation(GO:0051138)
0.0	1.3	GO:1902895	positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0	1.3	GO:0019048	modulation by virus of host morphology or physiology(GO:0019048)
0.0	1.3	GO:0001523	retinoid metabolic process(GO:0001523)
0.4	1.2	GO:1903570	regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1	1.2	GO:2001214	positive regulation of vasculogenesis(GO:2001214)
0.0	1.2	GO:0048009	insulin-like growth factor receptor signaling pathway(GO:0048009)
0.4	1.1	GO:0003365	establishment of cell polarity involved in ameboidal cell migration(GO:0003365)

Showing 1 to 10 of 219 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	3.1	GO:0043296	apical junction complex(GO:0043296)
0.7	2.1	GO:0070195	growth hormone receptor complex(GO:0070195)
0.0	2.1	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	2.1	GO:0032587	ruffle membrane(GO:0032587)
0.0	2.1	GO:0043202	lysosomal lumen(GO:0043202)
0.3	1.9	GO:0005899	insulin receptor complex(GO:0005899)
0.3	1.8	GO:0071148	TEAD-1-YAP complex(GO:0071148)
0.1	1.5	GO:0002116	semaphorin receptor complex(GO:0002116)
0.0	1.4	GO:0008180	COP9 signalosome(GO:0008180)
0.0	1.1	GO:0031941	filamentous actin(GO:0031941)

Showing 1 to 10 of 83 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.2	GO:0070064	proline-rich region binding(GO:0070064)
0.0	2.3	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.1	2.1	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0	2.0	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.0	1.8	GO:0001223	transcription coactivator binding(GO:0001223)
0.0	1.6	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.0	1.5	GO:0005112	Notch binding(GO:0005112)
0.0	1.3	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.2	1.2	GO:0043183	vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0	1.2	GO:0015459	potassium channel regulator activity(GO:0015459)

Showing 1 to 10 of 157 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	2.7	PID INSULIN PATHWAY	Insulin Pathway
0.0	2.3	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.1	2.2	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	2.2	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.0	1.7	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	1.6	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	1.3	PID NOTCH PATHWAY	Notch signaling pathway
0.0	1.2	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	1.1	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	1.1	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III

Showing 1 to 10 of 30 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.2	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	2.1	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	2.0	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.1	2.0	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	1.9	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	1.8	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	1.7	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.1	1.3	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.1	1.3	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	1.3	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane

Showing 1 to 10 of 48 entries

Results for AGCAGCA

Z-value: 0.66

Motif logo

miRNA associated with seed AGCAGCA

Activity profile of AGCAGCA motif

Sorted Z-values of AGCAGCA motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of AGCAGCA

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: