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Illumina Body Map 2
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Results for AGCUUAU
Z-value: 0.45
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miRNA associated with seed AGCUUAU
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr5_+_135364584 Show fit | 1.18 |
ENST00000442011.2
ENST00000305126.8 |
transforming growth factor, beta-induced, 68kDa |
|
| chr7_-_139876812 Show fit | 1.02 |
ENST00000397560.2
|
lysine (K)-specific demethylase 7A |
|
| chr4_+_124320665 Show fit | 1.00 |
ENST00000394339.2
|
sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
|
| chr3_+_30648066 Show fit | 0.88 |
ENST00000359013.4
|
transforming growth factor, beta receptor II (70/80kDa) |
|
| chr20_-_10654639 Show fit | 0.86 |
ENST00000254958.5
|
jagged 1 |
|
| chr2_-_19558373 Show fit | 0.85 |
ENST00000272223.2
|
odd-skipped related transciption factor 1 |
|
| chr3_+_152017181 Show fit | 0.83 |
ENST00000498502.1
ENST00000324196.5 ENST00000545754.1 ENST00000357472.3 |
muscleblind-like splicing regulator 1 |
|
| chr1_+_2160134 Show fit | 0.81 |
ENST00000378536.4
|
v-ski avian sarcoma viral oncogene homolog |
|
| chr13_+_73632897 Show fit | 0.77 |
ENST00000377687.4
|
Kruppel-like factor 5 (intestinal) |
|
| chr4_-_111544254 Show fit | 0.75 |
ENST00000306732.3
|
paired-like homeodomain 2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of AGCUUAU
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 1.6 | GO:0060940 | epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940) |
| 0.3 | 0.9 | GO:0002661 | B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663) |
| 0.2 | 0.9 | GO:0061073 | ciliary body morphogenesis(GO:0061073) |
| 0.2 | 0.9 | GO:0023016 | osmosensory signaling pathway(GO:0007231) signal transduction by trans-phosphorylation(GO:0023016) kidney smooth muscle tissue development(GO:0072194) pattern specification involved in metanephros development(GO:0072268) |
| 0.2 | 0.8 | GO:0060127 | subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578) |
| 0.1 | 0.8 | GO:0031064 | negative regulation of histone deacetylation(GO:0031064) |
| 0.1 | 0.8 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
| 0.1 | 0.7 | GO:0035897 | proteolysis in other organism(GO:0035897) |
| 0.1 | 0.7 | GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) |
| 0.0 | 0.7 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.9 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
| 0.0 | 0.8 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
| 0.0 | 0.6 | GO:0042587 | glycogen granule(GO:0042587) |
| 0.0 | 0.6 | GO:0005916 | fascia adherens(GO:0005916) |
| 0.1 | 0.5 | GO:0031251 | PAN complex(GO:0031251) |
| 0.0 | 0.5 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 0.0 | 0.5 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
| 0.0 | 0.4 | GO:0035068 | micro-ribonucleoprotein complex(GO:0035068) |
| 0.0 | 0.4 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 0.1 | 0.3 | GO:0020018 | ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.2 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.2 | 0.9 | GO:0005026 | transforming growth factor beta receptor activity, type II(GO:0005026) |
| 0.0 | 0.9 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.3 | 0.8 | GO:0035033 | histone deacetylase regulator activity(GO:0035033) |
| 0.2 | 0.8 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
| 0.0 | 0.8 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.0 | 0.7 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.0 | 0.6 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.0 | 0.6 | GO:0005112 | Notch binding(GO:0005112) |
| 0.0 | 0.5 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.2 | PID INTEGRIN3 PATHWAY | Beta3 integrin cell surface interactions |
| 0.0 | 1.4 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.0 | 1.2 | SIG PIP3 SIGNALING IN B LYMPHOCYTES | Genes related to PIP3 signaling in B lymphocytes |
| 0.0 | 1.1 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 0.5 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.0 | 0.4 | ST STAT3 PATHWAY | STAT3 Pathway |
| 0.0 | 0.4 | SA FAS SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
| 0.0 | 0.3 | PID WNT NONCANONICAL PATHWAY | Noncanonical Wnt signaling pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.2 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.0 | 1.0 | REACTOME EGFR DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.1 | 0.9 | REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
| 0.0 | 0.9 | REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
| 0.0 | 0.7 | REACTOME TRAF6 MEDIATED NFKB ACTIVATION | Genes involved in TRAF6 mediated NF-kB activation |
| 0.0 | 0.7 | REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION | Genes involved in activated TAK1 mediates p38 MAPK activation |
| 0.0 | 0.7 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.0 | 0.4 | REACTOME IRAK1 RECRUITS IKK COMPLEX | Genes involved in IRAK1 recruits IKK complex |
| 0.0 | 0.4 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.0 | 0.2 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |