ISMARA results: AGUGCAA

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Illumina Body Map 2

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Results for AGUGCAA

Z-value: 0.82

Motif logo

miRNA associated with seed AGUGCAA

Name	miRBASE accession
hsa-miR-130a-3p miRBase	MIMAT0000425
hsa-miR-130b-3p miRBase	MIMAT0000691
hsa-miR-301a-3p miRBase	MIMAT0000688
hsa-miR-301b-3p miRBase	MIMAT0004958
hsa-miR-454-3p miRBase	MIMAT0003885
hsa-miR-3666 miRBase	MIMAT0018088
hsa-miR-4295 miRBase	MIMAT0016844

Activity profile of AGUGCAA motif

Sorted Z-values of AGUGCAA motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr5_+_7396141 Show fit	2.24	ENST00000338316.4	ADCY2 Ensembl NCBI GeneCards UniProt NextProt Show fit	adenylate cyclase 2 (brain)
chr3_+_50712672 Show fit	1.85	ENST00000266037.9	DOCK3 Ensembl NCBI GeneCards UniProt NextProt Show fit	dedicator of cytokinesis 3
chr17_-_78450398 Show fit	1.80	ENST00000306773.4	NPTX1 Ensembl NCBI GeneCards UniProt NextProt Show fit	neuronal pentraxin I
chr2_+_103236004 Show fit	1.67	ENST00000233969.2	SLC9A2 Ensembl NCBI GeneCards UniProt NextProt Show fit	solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
chr5_-_136834982 Show fit	1.62	ENST00000510689.1 ENST00000394945.1	SPOCK1 Ensembl NCBI GeneCards UniProt NextProt Show fit	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr20_+_10199468 Show fit	1.57	ENST00000254976.2 ENST00000304886.2	SNAP25 Ensembl NCBI GeneCards UniProt NextProt Show fit	synaptosomal-associated protein, 25kDa
chr10_+_112404132 Show fit	1.53	ENST00000369519.3	RBM20 Ensembl NCBI GeneCards UniProt NextProt Show fit	RNA binding motif protein 20
chr16_-_77468945 Show fit	1.53	ENST00000282849.5	ADAMTS18 Ensembl NCBI GeneCards UniProt NextProt Show fit	ADAM metallopeptidase with thrombospondin type 1 motif, 18
chr3_-_179754706 Show fit	1.53	ENST00000465751.1 ENST00000467460.1	PEX5L Ensembl NCBI GeneCards UniProt NextProt Show fit	peroxisomal biogenesis factor 5-like
chr11_-_46940074 Show fit	1.40	ENST00000378623.1 ENST00000534404.1	LRP4 Ensembl NCBI GeneCards UniProt NextProt Show fit	low density lipoprotein receptor-related protein 4

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of AGUGCAA

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.5	GO:1904321	response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1	2.3	GO:0048665	neuron fate specification(GO:0048665)
0.1	1.7	GO:0098719	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.4	1.6	GO:1990926	short-term synaptic potentiation(GO:1990926)
0.1	1.6	GO:0090331	negative regulation of platelet aggregation(GO:0090331)
0.1	1.5	GO:0016560	protein import into peroxisome matrix, docking(GO:0016560)
0.0	1.5	GO:0033120	positive regulation of RNA splicing(GO:0033120)
0.5	1.4	GO:1904395	positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.1	1.4	GO:0006012	galactose metabolic process(GO:0006012)
0.4	1.3	GO:1901383	negative regulation of chorionic trophoblast cell proliferation(GO:1901383)

Showing 1 to 10 of 176 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.2	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.0	2.1	GO:0043195	terminal bouton(GO:0043195)
0.0	1.9	GO:0005778	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.2	1.6	GO:0070032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0	1.6	GO:0033268	node of Ranvier(GO:0033268)
0.1	1.4	GO:0016600	flotillin complex(GO:0016600)
0.1	1.4	GO:0000815	ESCRT III complex(GO:0000815)
0.0	1.4	GO:0042734	presynaptic membrane(GO:0042734)
0.3	1.3	GO:0048179	activin receptor complex(GO:0048179)
0.1	1.3	GO:0032584	growth cone membrane(GO:0032584)

Showing 1 to 10 of 66 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.9	GO:0017075	syntaxin-1 binding(GO:0017075)
0.1	2.3	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.1	2.2	GO:0008179	adenylate cyclase binding(GO:0008179)
0.1	1.7	GO:0015386	potassium:proton antiporter activity(GO:0015386)
0.1	1.7	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	1.7	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.0	1.7	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.2	1.5	GO:0005052	peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1	1.5	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.2	1.4	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)

Showing 1 to 10 of 115 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	3.9	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	2.6	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.1	2.2	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	1.9	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	1.8	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	1.7	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	1.7	PID MTOR 4PATHWAY	mTOR signaling pathway
0.0	1.6	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	1.2	PID CONE PATHWAY	Visual signal transduction: Cones
0.0	1.2	PID AURORA A PATHWAY	Aurora A signaling

Showing 1 to 10 of 22 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	2.6	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1	2.2	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.1	2.1	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	1.4	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	1.3	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	1.3	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	1.3	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	1.0	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	1.0	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	1.0	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors

Showing 1 to 10 of 46 entries

Results for AGUGCAA

Z-value: 0.82

Motif logo

miRNA associated with seed AGUGCAA

Activity profile of AGUGCAA motif

Sorted Z-values of AGUGCAA motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of AGUGCAA

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: