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Illumina Body Map 2
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Results for AGUGGUU
Z-value: 0.71
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miRNA associated with seed AGUGGUU
| Name | miRBASE accession |
|---|---|
|
hsa-miR-140-5p
|
MIMAT0000431 |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr1_-_228135599 Show fit | 3.29 |
ENST00000272164.5
|
wingless-type MMTV integration site family, member 9A |
|
| chr2_-_217560248 Show fit | 2.95 |
ENST00000233813.4
|
insulin-like growth factor binding protein 5 |
|
| chr5_+_32788945 Show fit | 2.60 |
ENST00000326958.1
|
AC026703.1 |
|
| chr6_+_168841817 Show fit | 2.50 |
ENST00000356284.2
ENST00000354536.5 |
SPARC related modular calcium binding 2 |
|
| chr5_+_32711419 Show fit | 2.17 |
ENST00000265074.8
|
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) |
|
| chr15_-_48937982 Show fit | 1.95 |
ENST00000316623.5
|
fibrillin 1 |
|
| chr5_-_172756506 Show fit | 1.93 |
ENST00000265087.4
|
stanniocalcin 2 |
|
| chr4_-_174451370 Show fit | 1.83 |
ENST00000359562.4
|
heart and neural crest derivatives expressed 2 |
|
| chr7_-_120498357 Show fit | 1.80 |
ENST00000415871.1
ENST00000222747.3 ENST00000430985.1 |
tetraspanin 12 |
|
| chr4_+_124320665 Show fit | 1.74 |
ENST00000394339.2
|
sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
Network of associatons between targets according to the STRING database.
First level regulatory network of AGUGGUU
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 3.0 | GO:1904204 | regulation of skeletal muscle hypertrophy(GO:1904204) |
| 0.1 | 2.9 | GO:0030157 | pancreatic juice secretion(GO:0030157) |
| 0.2 | 2.8 | GO:0061303 | cornea development in camera-type eye(GO:0061303) |
| 0.0 | 2.5 | GO:0010811 | positive regulation of cell-substrate adhesion(GO:0010811) |
| 0.1 | 2.1 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
| 0.2 | 1.9 | GO:0035582 | sequestering of BMP in extracellular matrix(GO:0035582) |
| 0.1 | 1.9 | GO:2001256 | regulation of store-operated calcium entry(GO:2001256) |
| 0.4 | 1.8 | GO:0061032 | cardiac right ventricle formation(GO:0003219) visceral serous pericardium development(GO:0061032) |
| 0.0 | 1.8 | GO:0010842 | retina layer formation(GO:0010842) |
| 0.4 | 1.7 | GO:0060940 | epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 6.9 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.3 | 3.0 | GO:0042567 | insulin-like growth factor ternary complex(GO:0042567) |
| 0.1 | 2.5 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.1 | 1.5 | GO:0001527 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.0 | 1.5 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.3 | 1.4 | GO:0043260 | laminin-1 complex(GO:0005606) laminin-11 complex(GO:0043260) |
| 0.2 | 1.3 | GO:0071148 | TEAD-1-YAP complex(GO:0071148) |
| 0.1 | 1.3 | GO:0016600 | flotillin complex(GO:0016600) |
| 0.1 | 1.1 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.1 | 1.0 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.1 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.2 | 3.0 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
| 0.1 | 2.4 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.0 | 2.4 | GO:0005179 | hormone activity(GO:0005179) |
| 0.3 | 2.2 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
| 0.0 | 1.9 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.1 | 1.8 | GO:0003680 | AT DNA binding(GO:0003680) |
| 0.4 | 1.5 | GO:0004727 | prenylated protein tyrosine phosphatase activity(GO:0004727) |
| 0.2 | 1.5 | GO:0030023 | extracellular matrix constituent conferring elasticity(GO:0030023) |
| 0.1 | 1.5 | GO:0042301 | phosphate ion binding(GO:0042301) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 5.8 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.0 | 2.8 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.0 | 1.6 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.0 | 1.4 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.0 | 1.3 | PID PDGFRA PATHWAY | PDGFR-alpha signaling pathway |
| 0.0 | 1.3 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.0 | 0.9 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 0.0 | 0.8 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 0.0 | 0.6 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.0 | 0.5 | PID ARF 3PATHWAY | Arf1 pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.0 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.0 | 3.0 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.0 | 2.4 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.0 | 1.7 | REACTOME EGFR DOWNREGULATION | Genes involved in EGFR downregulation |
| 0.0 | 1.5 | REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA | Genes involved in G beta:gamma signalling through PLC beta |
| 0.0 | 1.5 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.0 | 1.4 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.1 | 1.0 | REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
| 0.0 | 1.0 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |
| 0.0 | 0.8 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |