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Illumina Body Map 2

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Results for ATF5

Z-value: 0.95

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Transcription factors associated with ATF5

Gene Symbol Gene ID Gene Info
ENSG00000169136.4 activating transcription factor 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ATF5hg19_v2_chr19_+_50433476_50433510-0.336.8e-02Click!

Activity profile of ATF5 motif

Sorted Z-values of ATF5 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr20_-_52612705 6.28 ENST00000434986.2
breast carcinoma amplified sequence 1
chr20_-_52612468 4.98 ENST00000422805.1
breast carcinoma amplified sequence 1
chr14_+_23846210 4.00 ENST00000339180.4
ENST00000342473.4
ENST00000397227.3
ENST00000555731.1
CKLF-like MARVEL transmembrane domain containing 5
chr14_+_23846328 3.52 ENST00000382809.2
CKLF-like MARVEL transmembrane domain containing 5
chr14_+_23845995 3.44 ENST00000359320.3
CKLF-like MARVEL transmembrane domain containing 5
chr5_+_175223313 2.86 ENST00000359546.4
complexin 2
chr5_+_156887027 2.79 ENST00000435489.2
ENST00000311946.7
NIPA-like domain containing 4
chr2_-_87017985 2.77 ENST00000352580.3
CD8a molecule
chr2_-_87018784 2.69 ENST00000283635.3
ENST00000538832.1
CD8a molecule
chr14_+_92789498 2.42 ENST00000531433.1
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr7_-_3083472 2.31 ENST00000356408.3
caspase recruitment domain family, member 11
chr4_-_176733377 2.25 ENST00000505375.1
glycoprotein M6A
chr5_-_39219705 2.24 ENST00000351578.6
FYN binding protein
chr5_-_148442584 2.11 ENST00000394358.2
ENST00000512049.1
SH3 domain and tetratricopeptide repeats 2
chr5_-_39219641 2.07 ENST00000509072.1
ENST00000504542.1
ENST00000505428.1
ENST00000506557.1
FYN binding protein
chr5_-_148442687 2.04 ENST00000515425.1
SH3 domain and tetratricopeptide repeats 2
chr5_+_110559603 2.00 ENST00000512453.1
calcium/calmodulin-dependent protein kinase IV
chr22_-_37215523 1.98 ENST00000216200.5
parvalbumin
chr18_-_3845321 1.92 ENST00000539435.1
ENST00000400147.2
discs, large (Drosophila) homolog-associated protein 1
chr4_+_159442878 1.92 ENST00000307765.5
ENST00000423548.1
relaxin/insulin-like family peptide receptor 1
chr8_-_131028782 1.87 ENST00000519020.1
family with sequence similarity 49, member B
chr3_-_62861012 1.81 ENST00000357948.3
ENST00000383710.4
Ca++-dependent secretion activator
chr7_-_3083573 1.73 ENST00000396946.4
caspase recruitment domain family, member 11
chr2_+_191334212 1.61 ENST00000444317.1
ENST00000535751.1
major facilitator superfamily domain containing 6
chr6_-_62996066 1.60 ENST00000281156.4
KH domain containing, RNA binding, signal transduction associated 2
chr14_-_36988882 1.60 ENST00000498187.2
NK2 homeobox 1
chrX_-_13835147 1.58 ENST00000493677.1
ENST00000355135.2
glycoprotein M6B
chr4_+_159443024 1.54 ENST00000448688.2
relaxin/insulin-like family peptide receptor 1
chr5_+_110559312 1.53 ENST00000508074.1
calcium/calmodulin-dependent protein kinase IV
chrX_-_13835461 1.52 ENST00000316715.4
ENST00000356942.5
glycoprotein M6B
chr18_-_3845293 1.51 ENST00000400145.2
discs, large (Drosophila) homolog-associated protein 1
chr6_-_31514333 1.49 ENST00000376151.4
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
chr3_-_62860878 1.47 ENST00000283269.9
Ca++-dependent secretion activator
chr4_+_159443090 1.46 ENST00000343542.5
ENST00000470033.1
relaxin/insulin-like family peptide receptor 1
chr10_-_104179682 1.36 ENST00000406432.1
pleckstrin and Sec7 domain containing
chrX_-_13835398 1.35 ENST00000475307.1
glycoprotein M6B
chr8_-_131028869 1.34 ENST00000518283.1
ENST00000519110.1
family with sequence similarity 49, member B
chr10_-_104178857 1.34 ENST00000020673.5
pleckstrin and Sec7 domain containing
chr5_-_20575959 1.34 ENST00000507958.1
cadherin 18, type 2
chr20_+_58179582 1.31 ENST00000371015.1
ENST00000395639.4
phosphatase and actin regulator 3
chr16_+_28943260 1.31 ENST00000538922.1
ENST00000324662.3
ENST00000567541.1
CD19 molecule
chr17_-_7108436 1.30 ENST00000493294.1
discs, large homolog 4 (Drosophila)
chr2_+_173724771 1.26 ENST00000538974.1
ENST00000540783.1
Rap guanine nucleotide exchange factor (GEF) 4
chr19_-_8642289 1.25 ENST00000596675.1
ENST00000338257.8
myosin IF
chr16_-_30023615 1.25 ENST00000564979.1
ENST00000563378.1
double C2-like domains, alpha
chr1_+_202091980 1.24 ENST00000367282.5
G protein-coupled receptor 37 like 1
chr22_-_30662828 1.20 ENST00000403463.1
ENST00000215781.2
oncostatin M
chr3_+_101504200 1.19 ENST00000422132.1
neurexophilin and PC-esterase domain family, member 3
chr10_+_111765562 1.19 ENST00000360162.3
adducin 3 (gamma)
chr2_-_26205550 1.18 ENST00000405914.1
kinesin family member 3C
chr7_-_127672146 1.17 ENST00000476782.1
leucine rich repeat containing 4
chr6_+_72596604 1.14 ENST00000348717.5
ENST00000517960.1
ENST00000518273.1
ENST00000522291.1
ENST00000521978.1
ENST00000520567.1
ENST00000264839.7
regulating synaptic membrane exocytosis 1
chr12_+_10124110 1.14 ENST00000350667.4
C-type lectin domain family 12, member A
chr19_+_55795493 1.10 ENST00000309383.1
BR serine/threonine kinase 1
chr2_-_26205340 1.09 ENST00000264712.3
kinesin family member 3C
chr1_+_36023035 1.07 ENST00000373253.3
neurochondrin
chr5_+_173930676 1.07 ENST00000504512.1
RP11-267A15.1
chr11_-_132813566 1.04 ENST00000331898.7
opioid binding protein/cell adhesion molecule-like
chr1_+_36023370 1.03 ENST00000356090.4
ENST00000373243.2
neurochondrin
chr19_-_38916839 1.03 ENST00000433821.2
ENST00000426920.2
ENST00000587753.1
ENST00000454404.2
ENST00000293062.9
RAS guanyl releasing protein 4
chr14_+_79746249 1.02 ENST00000428277.2
neurexin 3
chrX_+_122318318 1.01 ENST00000371251.1
ENST00000371256.5
glutamate receptor, ionotropic, AMPA 3
chr3_-_183145765 1.00 ENST00000473233.1
MCF.2 cell line derived transforming sequence-like 2
chr7_+_136553824 0.98 ENST00000320658.5
ENST00000453373.1
ENST00000397608.3
ENST00000402486.3
ENST00000401861.1
cholinergic receptor, muscarinic 2
chr5_+_82767583 0.97 ENST00000512590.2
ENST00000513960.1
ENST00000513984.1
ENST00000502527.2
versican
chr1_+_66999799 0.97 ENST00000371035.3
ENST00000371036.3
ENST00000371037.4
SH3-domain GRB2-like (endophilin) interacting protein 1
chr17_+_44790515 0.97 ENST00000576346.1
N-ethylmaleimide-sensitive factor
chr19_-_7936344 0.96 ENST00000599142.1
Protein FLJ22184
chr8_+_79428539 0.95 ENST00000352966.5
protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chrX_-_19817869 0.94 ENST00000379698.4
SH3-domain kinase binding protein 1
chr11_-_132812987 0.94 ENST00000541867.1
opioid binding protein/cell adhesion molecule-like
chr5_+_175223715 0.94 ENST00000515502.1
complexin 2
chr3_-_183145873 0.93 ENST00000447025.2
ENST00000414362.2
ENST00000328913.3
MCF.2 cell line derived transforming sequence-like 2
chr12_+_125811162 0.92 ENST00000299308.3
transmembrane protein 132B
chr16_+_50313426 0.92 ENST00000569265.1
adenylate cyclase 7
chr11_-_132813627 0.92 ENST00000374778.4
opioid binding protein/cell adhesion molecule-like
chrX_+_122318224 0.91 ENST00000542149.1
glutamate receptor, ionotropic, AMPA 3
chr19_-_38916802 0.90 ENST00000587738.1
RAS guanyl releasing protein 4
chr1_-_183387723 0.90 ENST00000287713.6
nicotinamide nucleotide adenylyltransferase 2
chr5_+_82767487 0.89 ENST00000343200.5
ENST00000342785.4
versican
chr3_-_62860704 0.89 ENST00000490353.2
Ca++-dependent secretion activator
chr15_+_75118888 0.88 ENST00000395018.4
complexin 3
chr10_-_7453445 0.87 ENST00000379713.3
ENST00000397167.1
ENST00000397160.3
Scm-like with four mbt domains 2
chr12_-_54778444 0.85 ENST00000551771.1
zinc finger protein 385A
chr2_-_26700900 0.85 ENST00000338581.6
ENST00000339598.3
ENST00000402415.3
otoferlin
chr14_-_39901618 0.85 ENST00000554932.1
ENST00000298097.7
F-box protein 33
chr7_-_37488547 0.83 ENST00000453399.1
engulfment and cell motility 1
chr10_+_106918686 0.83 ENST00000393176.2
sortilin-related VPS10 domain containing receptor 3
chr2_-_145278475 0.83 ENST00000558170.2
zinc finger E-box binding homeobox 2
chr22_+_37678505 0.83 ENST00000402997.1
ENST00000405206.3
cytohesin 4
chrX_+_122318006 0.82 ENST00000371266.1
ENST00000264357.5
glutamate receptor, ionotropic, AMPA 3
chr12_-_16761117 0.82 ENST00000538051.1
LIM domain only 3 (rhombotin-like 2)
chr5_+_82767284 0.81 ENST00000265077.3
versican
chr12_+_10124001 0.81 ENST00000396507.3
ENST00000304361.4
ENST00000434319.2
C-type lectin domain family 12, member A
chr9_-_23825956 0.80 ENST00000397312.2
ELAV like neuron-specific RNA binding protein 2
chr11_-_104480019 0.79 ENST00000536529.1
ENST00000545630.1
ENST00000538641.1
RP11-886D15.1
chr11_-_126870655 0.78 ENST00000525144.2
kin of IRRE like 3 (Drosophila)
chr7_-_127671674 0.77 ENST00000478726.1
leucine rich repeat containing 4
chr6_+_72596406 0.77 ENST00000491071.2
regulating synaptic membrane exocytosis 1
chr19_-_38916822 0.76 ENST00000586305.1
RAS guanyl releasing protein 4
chr19_-_44285401 0.75 ENST00000262888.3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr12_-_49351303 0.74 ENST00000256682.4
ADP-ribosylation factor 3
chr12_-_54778471 0.74 ENST00000550120.1
ENST00000394313.2
ENST00000547210.1
zinc finger protein 385A
chr7_-_115670792 0.73 ENST00000265440.7
ENST00000393485.1
transcription factor EC
chr16_+_31271274 0.73 ENST00000287497.8
ENST00000544665.3
integrin, alpha M (complement component 3 receptor 3 subunit)
chr1_+_223354486 0.71 ENST00000446145.1
RP11-239E10.3
chr8_-_21645804 0.71 ENST00000518077.1
ENST00000517892.1
GDNF family receptor alpha 2
chr17_+_38337491 0.69 ENST00000538981.1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr12_-_16761007 0.69 ENST00000354662.1
ENST00000441439.2
LIM domain only 3 (rhombotin-like 2)
chr2_-_214016314 0.67 ENST00000434687.1
ENST00000374319.4
IKAROS family zinc finger 2 (Helios)
chr15_+_77287715 0.67 ENST00000559161.1
proline-serine-threonine phosphatase interacting protein 1
chr17_+_33914424 0.67 ENST00000590432.1
adaptor-related protein complex 2, beta 1 subunit
chr15_+_38296918 0.67 ENST00000557883.2
RP11-1008C21.1
chr9_-_23826298 0.66 ENST00000380117.1
ELAV like neuron-specific RNA binding protein 2
chr19_+_10531150 0.66 ENST00000352831.6
phosphodiesterase 4A, cAMP-specific
chr15_+_77287426 0.66 ENST00000558012.1
ENST00000267939.5
ENST00000379595.3
proline-serine-threonine phosphatase interacting protein 1
chr7_+_73498118 0.65 ENST00000336180.2
LIM domain kinase 1
chr7_-_100061869 0.64 ENST00000332375.3
chromosome 7 open reading frame 61
chr17_+_38334501 0.63 ENST00000541245.1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr1_+_206579736 0.63 ENST00000439126.1
SLIT-ROBO Rho GTPase activating protein 2
chr19_-_15090488 0.63 ENST00000594383.1
ENST00000598504.1
ENST00000597262.1
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
chr2_+_149447783 0.62 ENST00000449013.1
enhancer of polycomb homolog 2 (Drosophila)
chr1_-_182641037 0.60 ENST00000483095.2
regulator of G-protein signaling 8
chr7_-_78400364 0.59 ENST00000535697.1
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr2_-_197036289 0.58 ENST00000263955.4
serine/threonine kinase 17b
chr7_-_115670804 0.57 ENST00000320239.7
transcription factor EC
chr14_+_79745746 0.57 ENST00000281127.7
neurexin 3
chr1_+_48688357 0.57 ENST00000533824.1
ENST00000438567.2
ENST00000236495.5
ENST00000420136.2
solute carrier family 5 (sodium/sugar cotransporter), member 9
chr1_+_215179188 0.56 ENST00000391895.2
potassium channel, subfamily K, member 2
chr11_-_126870683 0.55 ENST00000525704.2
kin of IRRE like 3 (Drosophila)
chrX_+_131157609 0.54 ENST00000496850.1
Serine/threonine-protein kinase MST4
chr5_+_173930710 0.54 ENST00000511707.1
RP11-267A15.1
chr1_+_101361782 0.53 ENST00000357650.4
solute carrier family 30 (zinc transporter), member 7
chr20_+_54987305 0.53 ENST00000371336.3
ENST00000434344.1
Cas scaffolding protein family member 4
chr11_-_129062093 0.52 ENST00000310343.9
Rho GTPase activating protein 32
chr19_+_42773371 0.52 ENST00000571942.2
capicua transcriptional repressor
chr12_-_1920886 0.52 ENST00000536846.2
ENST00000538027.2
ENST00000538450.1
calcium channel, voltage-dependent, alpha 2/delta subunit 4
chr3_-_69129501 0.51 ENST00000540295.1
ENST00000415609.2
ENST00000361055.4
ENST00000349511.4
ubiquitin-like modifier activating enzyme 3
chr2_-_100759037 0.51 ENST00000317233.4
ENST00000423966.1
ENST00000416492.1
AF4/FMR2 family, member 3
chr1_-_182640988 0.51 ENST00000367556.1
regulator of G-protein signaling 8
chr7_-_102232891 0.50 ENST00000514917.2
RP11-514P8.7
chr9_+_127023704 0.46 ENST00000373596.1
ENST00000425237.1
NIMA-related kinase 6
chr8_-_61193947 0.46 ENST00000317995.4
carbonic anhydrase VIII
chr17_-_47287928 0.46 ENST00000507680.1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr20_+_54987168 0.46 ENST00000360314.3
Cas scaffolding protein family member 4
chr12_+_32654965 0.45 ENST00000472289.1
FYVE, RhoGEF and PH domain containing 4
chr5_+_132009675 0.44 ENST00000231449.2
ENST00000350025.2
interleukin 4
chr15_-_75871589 0.43 ENST00000306726.2
protein tyrosine phosphatase, non-receptor type 9
chr17_+_38334242 0.42 ENST00000436615.3
Rap guanine nucleotide exchange factor (GEF)-like 1
chr17_+_47287749 0.42 ENST00000419580.2
ABI family, member 3
chr12_-_25101920 0.42 ENST00000539780.1
ENST00000546285.1
ENST00000342945.5
branched chain amino-acid transaminase 1, cytosolic
chr12_-_54778244 0.42 ENST00000549937.1
zinc finger protein 385A
chr14_+_32547434 0.41 ENST00000556191.1
ENST00000554090.1
Rho GTPase activating protein 5
chr1_-_47697387 0.41 ENST00000371884.2
T-cell acute lymphocytic leukemia 1
chr5_+_138629628 0.40 ENST00000508689.1
ENST00000514528.1
matrin 3
chr8_+_38677850 0.39 ENST00000518809.1
ENST00000520611.1
transforming, acidic coiled-coil containing protein 1
chr14_+_100111447 0.38 ENST00000330710.5
ENST00000357223.2
HHIP-like 1
chr5_-_134788086 0.38 ENST00000537858.1
TRAF-interacting protein with forkhead-associated domain, family member B
chrX_-_19983260 0.37 ENST00000340625.3
chromosome X open reading frame 23
chr2_-_113542063 0.37 ENST00000263339.3
interleukin 1, alpha
chr8_-_21646290 0.37 ENST00000519195.1
GDNF family receptor alpha 2
chr15_+_78556428 0.36 ENST00000394855.3
ENST00000489435.2
DnaJ (Hsp40) homolog, subfamily A, member 4
chr17_+_18761417 0.36 ENST00000419284.2
ENST00000268835.2
ENST00000412418.1
ENST00000575228.1
ENST00000575102.1
ENST00000536323.1
phosphoribosyl pyrophosphate synthetase-associated protein 2
chr1_-_54872059 0.36 ENST00000371320.3
single stranded DNA binding protein 3
chr1_+_206137237 0.35 ENST00000468509.1
ENST00000367129.2
family with sequence similarity 72, member A
chr8_-_623547 0.35 ENST00000522893.1
glutamate-rich 1
chr6_+_87865262 0.33 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
zinc finger protein 292
chrX_+_122318113 0.33 ENST00000371264.3
glutamate receptor, ionotropic, AMPA 3
chr3_+_19988885 0.33 ENST00000422242.1
RAB5A, member RAS oncogene family
chr14_+_32546274 0.32 ENST00000396582.2
Rho GTPase activating protein 5
chr5_+_138629417 0.32 ENST00000510056.1
ENST00000511249.1
ENST00000503811.1
ENST00000511378.1
matrin 3
chr12_-_48597170 0.32 ENST00000310248.2
olfactory receptor, family 10, subfamily AD, member 1
chr9_+_103947311 0.31 ENST00000395056.2
Lipid phosphate phosphatase-related protein type 1
chr17_+_33914276 0.31 ENST00000592545.1
ENST00000538556.1
ENST00000312678.8
ENST00000589344.1
adaptor-related protein complex 2, beta 1 subunit
chr12_-_54652060 0.31 ENST00000552562.1
chromobox homolog 5
chr5_+_138629337 0.31 ENST00000394805.3
ENST00000512876.1
ENST00000513678.1
matrin 3
chr1_-_151319318 0.31 ENST00000436271.1
ENST00000450506.1
ENST00000422595.1
regulatory factor X, 5 (influences HLA class II expression)
chr15_+_63481668 0.31 ENST00000321437.4
ENST00000559006.1
ENST00000448330.2
RAB8B, member RAS oncogene family
chr11_-_33891362 0.31 ENST00000395833.3
LIM domain only 2 (rhombotin-like 1)
chr8_+_95731904 0.30 ENST00000522422.1
dpy-19-like 4 (C. elegans)
chrX_-_44402231 0.29 ENST00000378045.4
FUN14 domain containing 1
chr19_+_4229495 0.28 ENST00000221847.5
Epstein-Barr virus induced 3
chr5_+_138629389 0.28 ENST00000504045.1
ENST00000504311.1
ENST00000502499.1
matrin 3
chr8_+_107738343 0.28 ENST00000521592.1
oxidation resistance 1
chr8_+_107738240 0.28 ENST00000449762.2
ENST00000297447.6
oxidation resistance 1
chr1_-_156460391 0.28 ENST00000360595.3
myocyte enhancer factor 2D
chr1_-_151319283 0.28 ENST00000392746.3
regulatory factor X, 5 (influences HLA class II expression)
chr14_+_32546145 0.28 ENST00000556611.1
ENST00000539826.2
Rho GTPase activating protein 5
chr17_-_5522731 0.27 ENST00000576905.1
NLR family, pyrin domain containing 1
chr18_-_53089723 0.27 ENST00000561992.1
ENST00000562512.2
transcription factor 4
chr6_-_88411911 0.26 ENST00000257787.5
akirin 2
chrX_+_123095155 0.26 ENST00000371160.1
ENST00000435103.1
stromal antigen 2
chr3_+_23958470 0.26 ENST00000434031.2
ENST00000413699.1
ENST00000456530.2
ribosomal protein L15
chr4_-_175750364 0.25 ENST00000340217.5
ENST00000274093.3
glycine receptor, alpha 3
chr7_-_78400598 0.25 ENST00000536571.1
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr9_-_6007787 0.24 ENST00000399933.3
ENST00000381461.2
ENST00000513355.2
KIAA2026
chr1_-_36022979 0.24 ENST00000469892.1
ENST00000325722.3
KIAA0319-like
chr11_+_58938903 0.24 ENST00000532982.1
deltex homolog 4 (Drosophila)
chr17_+_33914460 0.24 ENST00000537622.2
adaptor-related protein complex 2, beta 1 subunit
chr3_+_19988566 0.24 ENST00000273047.4
RAB5A, member RAS oncogene family

Network of associatons between targets according to the STRING database.

First level regulatory network of ATF5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.5 GO:0002372 myeloid dendritic cell cytokine production(GO:0002372)
1.1 5.5 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.6 4.2 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
0.5 3.2 GO:2000568 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.4 1.3 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.4 4.5 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.3 2.0 GO:1902164 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.3 4.0 GO:0070970 interleukin-2 secretion(GO:0070970)
0.2 4.2 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.2 0.4 GO:0060018 astrocyte fate commitment(GO:0060018)
0.2 2.8 GO:0015693 magnesium ion transport(GO:0015693)
0.2 1.2 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.2 0.5 GO:0007113 endomitotic cell cycle(GO:0007113)
0.2 6.8 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.2 1.6 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.2 0.6 GO:0021816 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.2 1.2 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.1 0.9 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.1 3.8 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.1 1.6 GO:0021759 globus pallidus development(GO:0021759)
0.1 1.3 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.1 1.0 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.1 0.4 GO:0097065 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.1 3.5 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 0.6 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.1 0.4 GO:0071288 cellular response to mercury ion(GO:0071288) positive regulation of mononuclear cell migration(GO:0071677) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.1 1.0 GO:0035494 SNARE complex disassembly(GO:0035494)
0.1 1.1 GO:0021940 positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.1 1.5 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1 0.8 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.1 1.9 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.1 2.7 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 0.8 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 1.9 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.1 0.3 GO:1904784 NLRP1 inflammasome complex assembly(GO:1904784)
0.1 1.0 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.8 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 4.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.6 GO:0089712 L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712)
0.1 0.4 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.1 0.8 GO:0046541 saliva secretion(GO:0046541)
0.1 2.7 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.1 2.4 GO:0097186 amelogenesis(GO:0097186)
0.1 0.3 GO:0051461 positive regulation of corticotropin secretion(GO:0051461)
0.1 0.7 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.1 1.1 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1 1.1 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1 0.4 GO:0007356 thorax and anterior abdomen determination(GO:0007356)
0.1 0.8 GO:1900452 regulation of long term synaptic depression(GO:1900452)
0.1 1.1 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 2.2 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 3.1 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.4 GO:0002248 connective tissue replacement involved in inflammatory response wound healing(GO:0002248)
0.0 3.0 GO:0008038 neuron recognition(GO:0008038)
0.0 0.2 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.6 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 2.3 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.5 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.5 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 1.5 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.9 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.3 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 1.9 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 2.1 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.0 1.3 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.0 0.3 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.6 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.2 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 5.0 GO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway(GO:0007188)
0.0 0.3 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 1.6 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.0 3.0 GO:0016079 synaptic vesicle exocytosis(GO:0016079)
0.0 0.5 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:0035989 tendon development(GO:0035989)
0.0 0.0 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.0 0.4 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.2 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.8 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.7 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.6 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.3 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0 0.5 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.0 0.9 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.0 0.1 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.8 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.2 9.5 GO:0042101 T cell receptor complex(GO:0042101)
0.2 1.0 GO:0032279 asymmetric synapse(GO:0032279)
0.1 1.3 GO:0098839 postsynaptic density membrane(GO:0098839)
0.1 0.4 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.1 0.7 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.1 0.3 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
0.1 2.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 0.8 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.1 0.8 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 3.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.2 GO:0042585 germinal vesicle(GO:0042585)
0.1 0.6 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.6 GO:0044305 calyx of Held(GO:0044305)
0.1 1.5 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 1.3 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.9 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 2.3 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.6 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.3 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 1.9 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.3 GO:0051286 cell tip(GO:0051286)
0.0 2.3 GO:0097542 ciliary tip(GO:0097542)
0.0 0.8 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 1.1 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 7.4 GO:0043197 dendritic spine(GO:0043197)
0.0 12.0 GO:0098793 presynapse(GO:0098793)
0.0 5.1 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 3.9 GO:0055037 recycling endosome(GO:0055037)
0.0 1.9 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 2.7 GO:0005796 Golgi lumen(GO:0005796)
0.0 1.5 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.5 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 0.9 GO:0016235 aggresome(GO:0016235)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.2 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.3 1.3 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.3 2.4 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.2 0.5 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.2 4.0 GO:0050700 CARD domain binding(GO:0050700)
0.2 3.1 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 0.9 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.1 0.4 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.1 3.5 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 5.5 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 0.8 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 1.0 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 1.6 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 1.1 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1 0.8 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.1 2.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 3.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 2.7 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 4.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.6 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.4 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 0.2 GO:0005427 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.1 1.4 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1 0.6 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 2.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.7 GO:0001851 complement component C3b binding(GO:0001851)
0.0 0.3 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 1.1 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 1.6 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.4 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 1.2 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 1.0 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 1.9 GO:0030552 cAMP binding(GO:0030552)
0.0 1.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.3 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.4 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.6 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.9 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 0.1 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.0 7.2 GO:0005125 cytokine activity(GO:0005125)
0.0 3.0 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.4 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.5 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.3 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 2.8 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.8 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 2.2 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.8 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 2.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 2.1 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.8 GO:0070412 R-SMAD binding(GO:0070412)
0.0 1.2 GO:0030276 clathrin binding(GO:0030276)
0.0 0.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.9 GO:0003774 motor activity(GO:0003774)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 2.7 GO:0017124 SH3 domain binding(GO:0017124)
0.0 1.3 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.3 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 9.5 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.1 2.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 2.7 PID RAS PATHWAY Regulation of Ras family activation
0.0 3.5 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.2 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.9 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.3 ST GA12 PATHWAY G alpha 12 Pathway
0.0 1.6 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 1.3 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 0.5 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.7 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 1.6 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.4 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.7 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.5 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.9 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.7 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.3 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 4.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 2.7 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 1.9 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 1.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 2.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 4.5 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.1 6.8 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 4.0 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 2.2 REACTOME KINESINS Genes involved in Kinesins
0.0 0.6 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 1.5 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.6 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 1.0 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 1.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.9 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.8 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 4.7 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.7 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.6 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.3 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 2.4 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.7 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.6 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling