ISMARA results: ATF7

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Illumina Body Map 2

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Results for ATF7

Z-value: 0.80

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Transcription factors associated with ATF7

Gene Symbol	Gene ID	Gene Info
ATF7 Ensembl NCBI GeneCards UniProt NextProt	ENSG00000170653.14	activating transcription factor 7

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
ATF7	hg19_v2_chr12_-_54019755_54019804	0.50	3.3e-03	Click!

Activity profile of ATF7 motif

Sorted Z-values of ATF7 motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr22_-_44258360 Show fit	2.92	ENST00000330884.4 ENST00000249130.5	SULT4A1 Ensembl NCBI GeneCards UniProt NextProt Show fit	sulfotransferase family 4A, member 1
chr22_-_44258280 Show fit	2.59	ENST00000540422.1	SULT4A1 Ensembl NCBI GeneCards UniProt NextProt Show fit	sulfotransferase family 4A, member 1
chr11_-_77185094 Show fit	2.47	ENST00000278568.4 ENST00000356341.3	PAK1 Ensembl NCBI GeneCards UniProt NextProt Show fit	p21 protein (Cdc42/Rac)-activated kinase 1
chr14_+_93389425 Show fit	2.21	ENST00000216492.5 ENST00000334654.4	CHGA Ensembl NCBI GeneCards UniProt NextProt Show fit	chromogranin A (parathyroid secretory protein 1)
chr7_+_30174426 Show fit	1.83	ENST00000324453.8	C7orf41 Ensembl NCBI GeneCards UniProt NextProt Show fit	maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr11_+_66059339 Show fit	1.82	ENST00000327259.4	TMEM151A Ensembl NCBI GeneCards UniProt NextProt Show fit	transmembrane protein 151A
chr7_+_30174574 Show fit	1.76	ENST00000409688.1	C7orf41 Ensembl NCBI GeneCards UniProt NextProt Show fit	maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr7_+_30174668 Show fit	1.75	ENST00000415604.1	C7orf41 Ensembl NCBI GeneCards UniProt NextProt Show fit	maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr6_+_26204825 Show fit	1.75	ENST00000360441.4	HIST1H4E Ensembl NCBI GeneCards UniProt NextProt Show fit	histone cluster 1, H4e
chr12_-_123380610 Show fit	1.74	ENST00000535765.1	VPS37B Ensembl NCBI GeneCards UniProt NextProt Show fit	vacuolar protein sorting 37 homolog B (S. cerevisiae)

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of ATF7

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	6.7	GO:0050427	purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.1	2.7	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.2	2.5	GO:0061052	negative regulation of cell proliferation involved in contact inhibition(GO:0060244) negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.2	2.5	GO:0048245	eosinophil chemotaxis(GO:0048245)
0.7	2.2	GO:1901899	dense core granule biogenesis(GO:0061110) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of dense core granule biogenesis(GO:2000705)
0.1	2.1	GO:0045332	phospholipid translocation(GO:0045332)
0.0	2.1	GO:0010107	potassium ion import(GO:0010107)
0.2	2.0	GO:0099590	neurotransmitter receptor internalization(GO:0099590)
0.6	1.7	GO:1903774	positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1	1.7	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)

Showing 1 to 10 of 108 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.8	GO:0071437	invadopodium(GO:0071437)
0.1	2.5	GO:0031045	dense core granule(GO:0031045)
0.1	2.2	GO:0042583	chromaffin granule(GO:0042583)
0.0	2.1	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.1	2.0	GO:0036020	endolysosome membrane(GO:0036020)
0.2	1.7	GO:0098560	cytoplasmic side of late endosome membrane(GO:0098560)
0.1	1.7	GO:0000813	ESCRT I complex(GO:0000813)
0.0	1.5	GO:0014704	intercalated disc(GO:0014704)
0.0	1.5	GO:0030672	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0	1.4	GO:0031143	pseudopodium(GO:0031143)

Showing 1 to 10 of 59 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	6.7	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	3.1	GO:0048365	Rac GTPase binding(GO:0048365)
0.0	2.7	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.1	2.5	GO:0042056	chemoattractant activity(GO:0042056)
0.1	2.1	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1	2.1	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.1	2.0	GO:0098748	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0	2.0	GO:0005179	hormone activity(GO:0005179)
0.2	1.7	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0	1.7	GO:0030507	spectrin binding(GO:0030507)

Showing 1 to 10 of 72 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	4.2	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	2.9	PID IL12 2PATHWAY	IL12-mediated signaling events
0.0	2.8	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	1.8	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	1.1	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.0	1.0	PID ATM PATHWAY	ATM pathway
0.0	0.9	PID INSULIN PATHWAY	Insulin Pathway
0.0	0.8	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.6	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.6	PID FAS PATHWAY	FAS (CD95) signaling pathway

Showing 1 to 10 of 12 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	6.7	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	3.6	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.1	2.5	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	2.4	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	2.1	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	2.1	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.1	2.0	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.1	1.7	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.1	1.7	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1	1.4	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)

Showing 1 to 10 of 26 entries

Results for ATF7

Z-value: 0.80

Motif logo

Transcription factors associated with ATF7

Activity-expression correlation:

Activity profile of ATF7 motif

Sorted Z-values of ATF7 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of ATF7

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: