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Illumina Body Map 2
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Results for AUGGCUU
Z-value: 1.36
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miRNA associated with seed AUGGCUU
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr5_+_175223313 Show fit | 7.61 |
ENST00000359546.4
|
complexin 2 |
|
| chr8_+_24772455 Show fit | 5.97 |
ENST00000433454.2
|
neurofilament, medium polypeptide |
|
| chr9_-_19786926 Show fit | 4.93 |
ENST00000341998.2
ENST00000286344.3 |
solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 |
|
| chr9_-_93405352 Show fit | 4.46 |
ENST00000375765.3
|
DIRAS family, GTP-binding RAS-like 2 |
|
| chr6_+_123317116 Show fit | 4.40 |
ENST00000275162.5
|
clavesin 2 |
|
| chrX_+_12156582 Show fit | 4.33 |
ENST00000380682.1
|
FERM and PDZ domain containing 4 |
|
| chr1_+_181452678 Show fit | 4.20 |
ENST00000367570.1
ENST00000526775.1 ENST00000357570.5 ENST00000358338.5 ENST00000367567.4 |
calcium channel, voltage-dependent, R type, alpha 1E subunit |
|
| chr5_-_45696253 Show fit | 4.20 |
ENST00000303230.4
|
hyperpolarization activated cyclic nucleotide-gated potassium channel 1 |
|
| chr19_+_589893 Show fit | 4.12 |
ENST00000251287.2
|
hyperpolarization activated cyclic nucleotide-gated potassium channel 2 |
|
| chr15_+_27111510 Show fit | 4.11 |
ENST00000335625.5
|
gamma-aminobutyric acid (GABA) A receptor, alpha 5 |
Network of associatons between targets according to the STRING database.
First level regulatory network of AUGGCUU
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 7.6 | GO:0031915 | positive regulation of synaptic plasticity(GO:0031915) |
| 0.6 | 7.0 | GO:0042670 | retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549) |
| 0.3 | 6.6 | GO:0071420 | cellular response to histamine(GO:0071420) |
| 2.0 | 6.0 | GO:0033693 | neurofilament bundle assembly(GO:0033693) |
| 0.3 | 5.0 | GO:0008627 | intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627) |
| 0.1 | 4.9 | GO:0060292 | long term synaptic depression(GO:0060292) |
| 0.2 | 4.4 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
| 0.7 | 4.3 | GO:0051835 | positive regulation of synapse structural plasticity(GO:0051835) |
| 0.3 | 4.3 | GO:0098828 | positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828) |
| 0.0 | 4.3 | GO:0007040 | lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 10.8 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
| 0.2 | 10.2 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.9 | 9.2 | GO:0070554 | synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554) |
| 2.8 | 8.3 | GO:0098855 | HCN channel complex(GO:0098855) |
| 0.5 | 8.2 | GO:0005883 | neurofilament(GO:0005883) |
| 0.0 | 7.2 | GO:0043197 | dendritic spine(GO:0043197) |
| 0.0 | 6.7 | GO:0030426 | growth cone(GO:0030426) |
| 0.3 | 6.6 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.2 | 5.7 | GO:0033268 | node of Ranvier(GO:0033268) |
| 0.4 | 5.5 | GO:0042584 | chromaffin granule membrane(GO:0042584) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 14.2 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 1.7 | 8.3 | GO:0005222 | intracellular cAMP activated cation channel activity(GO:0005222) |
| 0.2 | 7.5 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.0 | 7.3 | GO:0015631 | tubulin binding(GO:0015631) |
| 0.0 | 7.1 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.6 | 4.9 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
| 0.0 | 4.9 | GO:0044325 | ion channel binding(GO:0044325) |
| 0.1 | 4.4 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.2 | 4.2 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.2 | 3.7 | GO:1905030 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.9 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 0.1 | 4.7 | SIG CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.1 | 4.3 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.1 | 3.9 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.1 | 3.2 | PID REELIN PATHWAY | Reelin signaling pathway |
| 0.0 | 2.8 | ST JNK MAPK PATHWAY | JNK MAPK Pathway |
| 0.0 | 2.4 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
| 0.0 | 1.9 | SIG PIP3 SIGNALING IN CARDIAC MYOCTES | Genes related to PIP3 signaling in cardiac myocytes |
| 0.0 | 1.7 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.0 | 1.1 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 10.8 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.1 | 10.8 | REACTOME POTASSIUM CHANNELS | Genes involved in Potassium Channels |
| 0.2 | 9.4 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.1 | 8.4 | REACTOME GLUCAGON TYPE LIGAND RECEPTORS | Genes involved in Glucagon-type ligand receptors |
| 0.3 | 6.2 | REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Dopamine Neurotransmitter Release Cycle |
| 0.0 | 6.1 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.1 | 3.4 | REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
| 0.1 | 2.9 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.1 | 2.9 | REACTOME SYNTHESIS OF PC | Genes involved in Synthesis of PC |
| 0.1 | 2.8 | REACTOME PLATELET CALCIUM HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |