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Illumina Body Map 2
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Results for BACH2
Z-value: 0.79
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Transcription factors associated with BACH2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| BACH2 | hg19_v2_chr6_-_91006461_91006517 | 0.34 | 6.0e-02 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of BACH2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 3.6 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
| 0.7 | 3.0 | GO:0002384 | hepatic immune response(GO:0002384) |
| 0.3 | 2.7 | GO:0031914 | negative regulation of synaptic plasticity(GO:0031914) |
| 0.0 | 2.6 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 0.0 | 2.0 | GO:0045669 | positive regulation of osteoblast differentiation(GO:0045669) |
| 0.3 | 1.9 | GO:0006196 | AMP catabolic process(GO:0006196) |
| 0.5 | 1.8 | GO:1990502 | dense core granule maturation(GO:1990502) |
| 0.6 | 1.7 | GO:0002372 | myeloid dendritic cell cytokine production(GO:0002372) |
| 0.3 | 1.6 | GO:0000117 | regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117) |
| 0.0 | 1.6 | GO:0019233 | sensory perception of pain(GO:0019233) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.4 | GO:0031430 | M band(GO:0031430) |
| 0.0 | 4.4 | GO:0042641 | actomyosin(GO:0042641) |
| 0.1 | 3.3 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.6 | 3.0 | GO:0005896 | interleukin-6 receptor complex(GO:0005896) |
| 0.0 | 3.0 | GO:0101002 | ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813) |
| 0.0 | 2.4 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.0 | 2.0 | GO:0043204 | perikaryon(GO:0043204) |
| 0.0 | 1.5 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.1 | 1.4 | GO:0098839 | postsynaptic density membrane(GO:0098839) |
| 0.0 | 1.3 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 3.6 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
| 0.1 | 3.2 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.7 | 2.1 | GO:0070119 | ciliary neurotrophic factor binding(GO:0070119) |
| 0.1 | 2.0 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.2 | 1.9 | GO:0047623 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.0 | 1.9 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.0 | 1.8 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.1 | 1.7 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 0.0 | 1.7 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.1 | 1.6 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.6 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.2 | 3.4 | ST STAT3 PATHWAY | STAT3 Pathway |
| 0.0 | 2.7 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.0 | 2.4 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 0.0 | 2.4 | PID VEGFR1 2 PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
| 0.0 | 2.1 | PID RET PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.0 | 1.7 | PID CD8 TCR DOWNSTREAM PATHWAY | Downstream signaling in naïve CD8+ T cells |
| 0.0 | 1.6 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.0 | 1.4 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.0 | 1.4 | PID FAK PATHWAY | Signaling events mediated by focal adhesion kinase |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.7 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.2 | 3.4 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.1 | 1.9 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 0.0 | 1.7 | REACTOME CA DEPENDENT EVENTS | Genes involved in Ca-dependent events |
| 0.1 | 1.4 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
| 0.0 | 1.3 | REACTOME ACTIVATION OF GENES BY ATF4 | Genes involved in Activation of Genes by ATF4 |
| 0.0 | 1.2 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 0.0 | 1.1 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.0 | 1.1 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.0 | 1.0 | REACTOME THE NLRP3 INFLAMMASOME | Genes involved in The NLRP3 inflammasome |