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Illumina Body Map 2
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Results for BCL6B
Z-value: 0.71
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Transcription factors associated with BCL6B
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| BCL6B | hg19_v2_chr17_+_6926339_6926377 | 0.59 | 4.0e-04 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of BCL6B
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 8.2 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.2 | 3.7 | GO:0006570 | tyrosine metabolic process(GO:0006570) |
| 0.4 | 3.2 | GO:0007598 | blood coagulation, extrinsic pathway(GO:0007598) |
| 0.2 | 2.8 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
| 0.1 | 2.5 | GO:0030277 | maintenance of gastrointestinal epithelium(GO:0030277) |
| 0.0 | 2.2 | GO:0045668 | negative regulation of osteoblast differentiation(GO:0045668) |
| 0.1 | 2.0 | GO:0006516 | glycoprotein catabolic process(GO:0006516) |
| 0.0 | 2.0 | GO:0050999 | regulation of nitric-oxide synthase activity(GO:0050999) |
| 0.5 | 1.8 | GO:1904425 | negative regulation of GTP binding(GO:1904425) |
| 0.4 | 1.8 | GO:0006114 | glycerol biosynthetic process(GO:0006114) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 5.5 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.0 | 4.1 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 3.5 | GO:0030666 | endocytic vesicle membrane(GO:0030666) |
| 0.1 | 3.4 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.2 | 2.8 | GO:0098647 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 0.0 | 2.5 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.0 | 1.8 | GO:0032154 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.0 | 1.6 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.1 | 1.5 | GO:0030478 | actin cap(GO:0030478) |
| 0.0 | 1.3 | GO:0000421 | autophagosome membrane(GO:0000421) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 6.0 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 5.3 | GO:0005518 | collagen binding(GO:0005518) |
| 0.5 | 3.7 | GO:0004447 | iodide peroxidase activity(GO:0004447) |
| 0.0 | 2.8 | GO:0005262 | calcium channel activity(GO:0005262) |
| 0.1 | 2.3 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.6 | 1.8 | GO:0004613 | phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613) |
| 0.2 | 1.8 | GO:0004687 | myosin light chain kinase activity(GO:0004687) |
| 0.0 | 1.8 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.4 | 1.7 | GO:0008336 | gamma-butyrobetaine dioxygenase activity(GO:0008336) |
| 0.1 | 1.6 | GO:0010314 | phosphatidylinositol-5-phosphate binding(GO:0010314) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 5.5 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.0 | 4.5 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 2.8 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 1.8 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.0 | 1.8 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 1.5 | PID VEGFR1 PATHWAY | VEGFR1 specific signals |
| 0.0 | 1.1 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 0.0 | 1.1 | ST GA13 PATHWAY | G alpha 13 Pathway |
| 0.0 | 1.1 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.0 | 0.8 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 5.9 | REACTOME AMINE DERIVED HORMONES | Genes involved in Amine-derived hormones |
| 0.1 | 3.7 | REACTOME ENOS ACTIVATION AND REGULATION | Genes involved in eNOS activation and regulation |
| 0.1 | 3.3 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.1 | 2.9 | REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE | Genes involved in Formation of Fibrin Clot (Clotting Cascade) |
| 0.1 | 2.8 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.1 | 1.8 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
| 0.1 | 1.5 | REACTOME SIGNAL ATTENUATION | Genes involved in Signal attenuation |
| 0.0 | 1.4 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.0 | 1.3 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.0 | 1.2 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |