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Illumina Body Map 2
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Results for CBFB
Z-value: 0.68
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Transcription factors associated with CBFB
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| CBFB | hg19_v2_chr16_+_67063142_67063153 | 0.21 | 2.6e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr20_+_43343886 Show fit | 2.54 |
ENST00000190983.4
|
WNT1 inducible signaling pathway protein 2 |
|
| chr6_-_75912508 Show fit | 2.09 |
ENST00000416123.2
|
collagen, type XII, alpha 1 |
|
| chr22_+_23222886 Show fit | 2.04 |
ENST00000390319.2
|
immunoglobulin lambda variable 3-1 |
|
| chr14_-_61116168 Show fit | 1.97 |
ENST00000247182.6
|
SIX homeobox 1 |
|
| chr1_+_47264711 Show fit | 1.94 |
ENST00000371923.4
ENST00000271153.4 ENST00000371919.4 |
cytochrome P450, family 4, subfamily B, polypeptide 1 |
|
| chr20_+_44637526 Show fit | 1.61 |
ENST00000372330.3
|
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) |
|
| chr3_-_99569821 Show fit | 1.40 |
ENST00000487087.1
|
filamin A interacting protein 1-like |
|
| chr4_+_71091786 Show fit | 1.29 |
ENST00000317987.5
|
follicular dendritic cell secreted protein |
|
| chr14_-_24977457 Show fit | 1.21 |
ENST00000250378.3
ENST00000206446.4 |
chymase 1, mast cell |
|
| chr2_-_158300556 Show fit | 1.19 |
ENST00000264192.3
|
cytohesin 1 interacting protein |
Network of associatons between targets according to the STRING database.
First level regulatory network of CBFB
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.1 | GO:0030199 | collagen fibril organization(GO:0030199) |
| 0.5 | 2.0 | GO:2000729 | positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729) |
| 0.0 | 2.0 | GO:0030449 | regulation of complement activation(GO:0030449) |
| 0.2 | 1.9 | GO:0018879 | biphenyl metabolic process(GO:0018879) |
| 0.2 | 1.6 | GO:0051549 | positive regulation of keratinocyte migration(GO:0051549) |
| 0.5 | 1.5 | GO:0061033 | secretion by lung epithelial cell involved in lung growth(GO:0061033) |
| 0.4 | 1.2 | GO:0050720 | interleukin-1 beta biosynthetic process(GO:0050720) |
| 0.1 | 1.2 | GO:0031914 | negative regulation of synaptic plasticity(GO:0031914) |
| 0.0 | 1.2 | GO:0045987 | positive regulation of smooth muscle contraction(GO:0045987) |
| 0.2 | 1.1 | GO:0061343 | cell adhesion involved in heart morphogenesis(GO:0061343) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.3 | GO:1904724 | tertiary granule lumen(GO:1904724) |
| 0.7 | 2.1 | GO:0005595 | collagen type XII trimer(GO:0005595) |
| 0.0 | 0.5 | GO:0036449 | microtubule minus-end(GO:0036449) |
| 0.0 | 0.3 | GO:0071144 | SMAD2-SMAD3 protein complex(GO:0071144) |
| 0.0 | 0.3 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 0.0 | 0.2 | GO:0032039 | integrator complex(GO:0032039) |
| 0.0 | 0.1 | GO:0034669 | integrin alpha4-beta7 complex(GO:0034669) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.9 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.1 | 2.6 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.1 | 2.5 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
| 0.2 | 2.1 | GO:0030020 | extracellular matrix structural constituent conferring tensile strength(GO:0030020) |
| 0.1 | 2.0 | GO:0001223 | transcription coactivator binding(GO:0001223) |
| 0.1 | 1.9 | GO:0070330 | aromatase activity(GO:0070330) |
| 0.0 | 1.2 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.0 | 1.1 | GO:0017147 | Wnt-protein binding(GO:0017147) |
| 0.2 | 1.0 | GO:0004698 | calcium-dependent protein kinase C activity(GO:0004698) |
| 0.0 | 1.0 | GO:0000175 | 3'-5'-exoribonuclease activity(GO:0000175) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.7 | PID SYNDECAN 1 PATHWAY | Syndecan-1-mediated signaling events |
| 0.0 | 1.3 | PID IL12 2PATHWAY | IL12-mediated signaling events |
| 0.0 | 1.2 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.0 | 1.1 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.1 | 0.8 | ST INTERFERON GAMMA PATHWAY | Interferon gamma pathway. |
| 0.0 | 0.6 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.0 | 0.2 | PID IL27 PATHWAY | IL27-mediated signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.8 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.0 | 1.9 | REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
| 0.0 | 1.7 | REACTOME EXTRACELLULAR MATRIX ORGANIZATION | Genes involved in Extracellular matrix organization |
| 0.1 | 1.5 | REACTOME ACTIVATED POINT MUTANTS OF FGFR2 | Genes involved in Activated point mutants of FGFR2 |
| 0.0 | 1.2 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.0 | 0.9 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
| 0.0 | 0.8 | REACTOME REGULATION OF IFNG SIGNALING | Genes involved in Regulation of IFNG signaling |
| 0.0 | 0.7 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.0 | 0.4 | REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |