ISMARA results: CDX1

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Illumina Body Map 2

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Results for CDX1

Z-value: 0.96

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Transcription factors associated with CDX1

Gene Symbol	Gene ID	Gene Info
CDX1 Ensembl NCBI GeneCards UniProt NextProt	ENSG00000113722.12	caudal type homeobox 1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
CDX1	hg19_v2_chr5_+_149546334_149546364	-0.10	5.8e-01	Click!

Activity profile of CDX1 motif

Sorted Z-values of CDX1 motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr2_-_88427568 Show fit	5.41	ENST00000393750.3 ENST00000295834.3	FABP1 Ensembl NCBI GeneCards UniProt NextProt Show fit	fatty acid binding protein 1, liver
chr5_-_147211226 Show fit	4.13	ENST00000296695.5	SPINK1 Ensembl NCBI GeneCards UniProt NextProt Show fit	serine peptidase inhibitor, Kazal type 1
chr20_+_56136136 Show fit	2.75	ENST00000319441.4 ENST00000543666.1	PCK1 Ensembl NCBI GeneCards UniProt NextProt Show fit	phosphoenolpyruvate carboxykinase 1 (soluble)
chr5_-_41261540 Show fit	2.48	ENST00000263413.3	C6 Ensembl NCBI GeneCards UniProt NextProt Show fit	complement component 6
chr1_+_159557607 Show fit	2.02	ENST00000255040.2	APCS Ensembl NCBI GeneCards UniProt NextProt Show fit	amyloid P component, serum
chr2_-_151344172 Show fit	2.00	ENST00000375734.2 ENST00000263895.4 ENST00000454202.1	RND3 Ensembl NCBI GeneCards UniProt NextProt Show fit	Rho family GTPase 3
chr7_-_16840820 Show fit	1.98	ENST00000450569.1	AGR2 Ensembl NCBI GeneCards UniProt NextProt Show fit	anterior gradient 2
chr11_+_114168085 Show fit	1.95	ENST00000541754.1	NNMT Ensembl NCBI GeneCards UniProt NextProt Show fit	nicotinamide N-methyltransferase
chr11_+_112046190 Show fit	1.89	ENST00000357685.5 ENST00000393032.2 ENST00000361053.4	BCO2 Ensembl NCBI GeneCards UniProt NextProt Show fit	beta-carotene oxygenase 2
chr16_+_56672571 Show fit	1.84	ENST00000290705.8	MT1A Ensembl NCBI GeneCards UniProt NextProt Show fit	metallothionein 1A

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of CDX1

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	9.3	GO:0030449	regulation of complement activation(GO:0030449)
0.9	5.5	GO:0010751	negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.3	5.4	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
0.1	4.7	GO:0061049	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.2	4.5	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
1.2	3.5	GO:0001868	regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.1	3.4	GO:0071294	cellular response to zinc ion(GO:0071294)
0.3	3.0	GO:2000332	blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.9	2.8	GO:0042214	terpene metabolic process(GO:0042214)
0.7	2.8	GO:0006114	glycerol biosynthetic process(GO:0006114)

Showing 1 to 10 of 172 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	11.7	GO:0072562	blood microparticle(GO:0072562)
0.0	6.4	GO:0030018	Z disc(GO:0030018)
0.3	5.4	GO:0045179	apical cortex(GO:0045179)
0.0	5.4	GO:0001669	acrosomal vesicle(GO:0001669)
0.4	3.7	GO:0005579	membrane attack complex(GO:0005579)
0.1	3.5	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	3.5	GO:0031941	filamentous actin(GO:0031941)
0.1	3.2	GO:0097381	photoreceptor disc membrane(GO:0097381)
0.1	3.1	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.2	3.0	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)

Showing 1 to 10 of 56 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	6.5	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.8	5.4	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.1	5.3	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	4.3	GO:0005044	scavenger receptor activity(GO:0005044)
0.0	4.1	GO:0005518	collagen binding(GO:0005518)
0.5	3.5	GO:0043120	tumor necrosis factor binding(GO:0043120)
0.3	3.0	GO:0070892	lipoteichoic acid receptor activity(GO:0070892)
0.2	3.0	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.9	2.8	GO:0004613	phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0	2.8	GO:0003727	single-stranded RNA binding(GO:0003727)

Showing 1 to 10 of 120 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	6.3	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	5.9	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	3.6	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	2.7	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	1.9	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	1.6	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	1.4	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.0	1.4	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	1.2	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	1.1	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods

Showing 1 to 10 of 21 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	8.4	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.2	7.3	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.2	5.0	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.1	3.9	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	3.8	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.1	3.7	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	3.0	REACTOME MRNA PROCESSING	Genes involved in mRNA Processing
0.2	2.8	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	2.5	REACTOME AMYLOIDS	Genes involved in Amyloids
0.1	1.9	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation

Showing 1 to 10 of 46 entries

Results for CDX1

Z-value: 0.96

Motif logo

Transcription factors associated with CDX1

Activity-expression correlation:

Activity profile of CDX1 motif

Sorted Z-values of CDX1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of CDX1

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: