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Illumina Body Map 2

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Results for CEBPB

Z-value: 1.85

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Transcription factors associated with CEBPB

Gene Symbol Gene ID Gene Info
CEBPB
ENSG00000172216.4 CCAAT enhancer binding protein beta

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CEBPBhg19_v2_chr20_+_48807351_488073840.318.5e-02Click!

Activity profile of CEBPB motif

Sorted Z-values of CEBPB motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr20_+_56136136 9.15 ENST00000319441.4
ENST00000543666.1
PCK1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr4_-_155533787 8.32 ENST00000407946.1
ENST00000405164.1
ENST00000336098.3
ENST00000393846.2
ENST00000404648.3
ENST00000443553.1
FGG
fibrinogen gamma chain
chr20_+_36974759 7.74 ENST00000217407.2
LBP
lipopolysaccharide binding protein
chr17_-_64216748 7.59 ENST00000585162.1
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr5_-_141704566 4.97 ENST00000344120.4
ENST00000434127.2
SPRY4
sprouty homolog 4 (Drosophila)
chr3_+_186435065 4.84 ENST00000287611.2
ENST00000265023.4
KNG1
kininogen 1
chr20_+_361890 4.82 ENST00000449710.1
ENST00000422053.2
TRIB3
tribbles pseudokinase 3
chr2_+_211421262 4.76 ENST00000233072.5
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chr2_-_216300784 4.71 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
FN1
fibronectin 1
chr9_-_34691201 4.55 ENST00000378800.3
ENST00000311925.2
CCL19
chemokine (C-C motif) ligand 19
chr3_-_49722523 4.47 ENST00000448220.1
MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr3_+_186435137 4.19 ENST00000447445.1
KNG1
kininogen 1
chr6_+_31895287 4.12 ENST00000447952.2
C2
complement component 2
chr6_+_31895254 4.11 ENST00000299367.5
ENST00000442278.2
C2
complement component 2
chr16_+_72088376 4.04 ENST00000570083.1
ENST00000355906.5
ENST00000398131.2
ENST00000569639.1
ENST00000564499.1
ENST00000357763.4
ENST00000562526.1
ENST00000565574.1
ENST00000568417.2
ENST00000356967.5
HP
HPR
haptoglobin
haptoglobin-related protein
chr20_+_361261 3.97 ENST00000217233.3
TRIB3
tribbles pseudokinase 3
chr17_+_1665306 3.86 ENST00000571360.1
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr6_+_31895467 3.85 ENST00000556679.1
ENST00000456570.1
CFB
CFB
complement factor B
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr12_+_57849048 3.83 ENST00000266646.2
INHBE
inhibin, beta E
chr3_+_157154578 3.80 ENST00000295927.3
PTX3
pentraxin 3, long
chr3_+_12392971 3.70 ENST00000287820.6
PPARG
peroxisome proliferator-activated receptor gamma
chr12_-_56236711 3.62 ENST00000409200.3
MMP19
matrix metallopeptidase 19
chr22_+_35776828 3.57 ENST00000216117.8
HMOX1
heme oxygenase (decycling) 1
chr5_+_150400124 3.55 ENST00000388825.4
ENST00000521650.1
ENST00000517973.1
GPX3
glutathione peroxidase 3 (plasma)
chr6_+_31895480 3.47 ENST00000418949.2
ENST00000383177.3
ENST00000477310.1
C2
CFB
complement component 2
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr17_+_1665345 3.46 ENST00000576406.1
ENST00000571149.1
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr19_-_11347173 3.46 ENST00000587656.1
DOCK6
dedicator of cytokinesis 6
chr12_-_56236690 3.42 ENST00000322569.4
MMP19
matrix metallopeptidase 19
chr16_-_28550348 3.34 ENST00000324873.6
NUPR1
nuclear protein, transcriptional regulator, 1
chr12_-_56236734 3.33 ENST00000548629.1
MMP19
matrix metallopeptidase 19
chr17_+_1665253 3.30 ENST00000254722.4
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr1_+_212782012 3.26 ENST00000341491.4
ENST00000366985.1
ATF3
activating transcription factor 3
chr16_-_28550320 3.19 ENST00000395641.2
NUPR1
nuclear protein, transcriptional regulator, 1
chr8_+_22250334 2.95 ENST00000520832.1
SLC39A14
solute carrier family 39 (zinc transporter), member 14
chr1_+_153232160 2.80 ENST00000368742.3
LOR
loricrin
chr20_+_9966728 2.79 ENST00000449270.1
RP5-839B4.8
RP5-839B4.8
chr3_+_42897512 2.77 ENST00000493193.1
ACKR2
atypical chemokine receptor 2
chr12_-_96390108 2.75 ENST00000538703.1
ENST00000261208.3
HAL
histidine ammonia-lyase
chr19_-_4540486 2.71 ENST00000306390.6
LRG1
leucine-rich alpha-2-glycoprotein 1
chr11_+_47279155 2.70 ENST00000444396.1
ENST00000457932.1
ENST00000412937.1
NR1H3
nuclear receptor subfamily 1, group H, member 3
chr11_+_47279248 2.62 ENST00000449369.1
NR1H3
nuclear receptor subfamily 1, group H, member 3
chr21_-_44495964 2.61 ENST00000398168.1
ENST00000398165.3
CBS
cystathionine-beta-synthase
chr12_+_57623869 2.60 ENST00000414700.3
ENST00000557703.1
SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
chrX_-_55024967 2.56 ENST00000545676.1
PFKFB1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr1_-_203198790 2.49 ENST00000367229.1
ENST00000255427.3
ENST00000535569.1
CHIT1
chitinase 1 (chitotriosidase)
chr5_+_52083730 2.49 ENST00000282588.6
ENST00000274311.2
ITGA1
PELO
integrin, alpha 1
pelota homolog (Drosophila)
chr19_-_33360647 2.48 ENST00000590341.1
ENST00000587772.1
ENST00000023064.4
SLC7A9
solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
chr11_+_7506713 2.46 ENST00000329293.3
ENST00000534244.1
OLFML1
olfactomedin-like 1
chr21_-_44495919 2.45 ENST00000398158.1
CBS
cystathionine-beta-synthase
chr12_+_57624119 2.45 ENST00000555773.1
ENST00000554975.1
ENST00000449049.3
ENST00000393827.4
SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
chr12_+_57623477 2.44 ENST00000557487.1
ENST00000555634.1
ENST00000556689.1
SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
chr11_+_47279504 2.44 ENST00000441012.2
ENST00000437276.1
ENST00000436029.1
ENST00000467728.1
ENST00000405853.3
NR1H3
nuclear receptor subfamily 1, group H, member 3
chr12_+_57624085 2.41 ENST00000553474.1
SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
chrX_+_13587712 2.31 ENST00000361306.1
ENST00000380602.3
EGFL6
EGF-like-domain, multiple 6
chr1_-_196577489 2.30 ENST00000609185.1
ENST00000451324.2
ENST00000367433.5
ENST00000367431.4
KCNT2
potassium channel, subfamily T, member 2
chr12_+_57623907 2.28 ENST00000553529.1
ENST00000554310.1
SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
chr6_-_55739542 2.28 ENST00000446683.2
BMP5
bone morphogenetic protein 5
chr9_-_95298254 2.24 ENST00000444490.2
ECM2
extracellular matrix protein 2, female organ and adipocyte specific
chr11_-_102595681 2.23 ENST00000236826.3
MMP8
matrix metallopeptidase 8 (neutrophil collagenase)
chr14_-_92413353 2.20 ENST00000556154.1
FBLN5
fibulin 5
chr2_-_217559517 2.11 ENST00000449583.1
IGFBP5
insulin-like growth factor binding protein 5
chr11_+_7506837 2.11 ENST00000528758.1
OLFML1
olfactomedin-like 1
chr1_+_99127225 2.08 ENST00000370189.5
ENST00000529992.1
SNX7
sorting nexin 7
chr9_+_131683174 2.05 ENST00000372592.3
ENST00000428610.1
PHYHD1
phytanoyl-CoA dioxygenase domain containing 1
chr10_+_26727333 2.04 ENST00000356785.4
APBB1IP
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr19_-_36004543 2.00 ENST00000339686.3
ENST00000447113.2
ENST00000440396.1
DMKN
dermokine
chr1_+_28586006 1.99 ENST00000253063.3
SESN2
sestrin 2
chr9_-_13175823 1.98 ENST00000545857.1
MPDZ
multiple PDZ domain protein
chr12_+_57624059 1.97 ENST00000557427.1
SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
chr5_+_38845960 1.93 ENST00000502536.1
OSMR
oncostatin M receptor
chr19_+_11350278 1.92 ENST00000252453.8
C19orf80
chromosome 19 open reading frame 80
chr1_-_27952741 1.90 ENST00000399173.1
FGR
feline Gardner-Rasheed sarcoma viral oncogene homolog
chr11_+_7506584 1.90 ENST00000530135.1
OLFML1
olfactomedin-like 1
chr7_+_114562616 1.89 ENST00000448022.1
MDFIC
MyoD family inhibitor domain containing
chr1_-_207143802 1.88 ENST00000324852.4
ENST00000400962.3
FCAMR
Fc receptor, IgA, IgM, high affinity
chr15_+_96869165 1.88 ENST00000421109.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr12_-_96390063 1.86 ENST00000541929.1
HAL
histidine ammonia-lyase
chr2_-_160654745 1.86 ENST00000259053.4
ENST00000429078.2
CD302
CD302 molecule
chr1_-_27953031 1.85 ENST00000374003.3
FGR
feline Gardner-Rasheed sarcoma viral oncogene homolog
chrX_-_32173579 1.76 ENST00000359836.1
ENST00000343523.2
ENST00000378707.3
ENST00000541735.1
ENST00000474231.1
DMD
dystrophin
chr10_+_26727125 1.74 ENST00000376236.4
APBB1IP
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr22_-_30901637 1.71 ENST00000381982.3
ENST00000255858.7
ENST00000540456.1
ENST00000392772.2
SEC14L4
SEC14-like 4 (S. cerevisiae)
chr5_+_150020214 1.71 ENST00000307662.4
SYNPO
synaptopodin
chr2_+_7118755 1.69 ENST00000433456.1
RNF144A
ring finger protein 144A
chr12_-_96389702 1.68 ENST00000552509.1
HAL
histidine ammonia-lyase
chr10_+_101542462 1.68 ENST00000370449.4
ENST00000370434.1
ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr1_-_27952617 1.65 ENST00000457296.1
FGR
feline Gardner-Rasheed sarcoma viral oncogene homolog
chr1_+_53480598 1.65 ENST00000430330.2
ENST00000408941.3
ENST00000478274.2
ENST00000484100.1
ENST00000435345.2
ENST00000488965.1
SCP2
sterol carrier protein 2
chr1_+_53527854 1.64 ENST00000371500.3
ENST00000395871.2
ENST00000312553.5
PODN
podocan
chr6_+_151187074 1.63 ENST00000367308.4
MTHFD1L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr1_+_221051699 1.63 ENST00000366903.6
HLX
H2.0-like homeobox
chr5_+_38846101 1.59 ENST00000274276.3
OSMR
oncostatin M receptor
chr2_+_113885138 1.55 ENST00000409930.3
IL1RN
interleukin 1 receptor antagonist
chr5_-_150473127 1.50 ENST00000521001.1
TNIP1
TNFAIP3 interacting protein 1
chrX_+_99839799 1.47 ENST00000373031.4
TNMD
tenomodulin
chr5_+_73109339 1.47 ENST00000296799.4
ARHGEF28
Rho guanine nucleotide exchange factor (GEF) 28
chr7_+_114562172 1.46 ENST00000393486.1
ENST00000257724.3
MDFIC
MyoD family inhibitor domain containing
chrX_+_24072833 1.45 ENST00000253039.4
EIF2S3
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
chr22_-_30642728 1.43 ENST00000403987.3
LIF
leukemia inhibitory factor
chr1_+_162601774 1.40 ENST00000415555.1
DDR2
discoidin domain receptor tyrosine kinase 2
chr12_+_10366223 1.40 ENST00000545290.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr7_+_48211048 1.39 ENST00000435803.1
ABCA13
ATP-binding cassette, sub-family A (ABC1), member 13
chr19_+_49259325 1.39 ENST00000222157.3
FGF21
fibroblast growth factor 21
chr15_+_89182156 1.37 ENST00000379224.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr14_-_92413727 1.37 ENST00000267620.10
FBLN5
fibulin 5
chr15_+_89181974 1.35 ENST00000306072.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr6_+_151187615 1.34 ENST00000441122.1
ENST00000423867.1
MTHFD1L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chrX_-_106243451 1.34 ENST00000355610.4
ENST00000535534.1
MORC4
MORC family CW-type zinc finger 4
chr15_+_89182178 1.33 ENST00000559876.1
ISG20
interferon stimulated exonuclease gene 20kDa
chr1_+_112016414 1.33 ENST00000343534.5
ENST00000369718.3
C1orf162
chromosome 1 open reading frame 162
chr11_-_102595512 1.32 ENST00000438475.2
MMP8
matrix metallopeptidase 8 (neutrophil collagenase)
chr1_-_36945097 1.31 ENST00000331941.5
ENST00000418048.2
ENST00000338937.5
ENST00000440588.2
CSF3R
colony stimulating factor 3 receptor (granulocyte)
chr16_-_57809015 1.30 ENST00000540079.2
ENST00000569222.1
KIFC3
kinesin family member C3
chr17_+_39846114 1.28 ENST00000586699.1
EIF1
eukaryotic translation initiation factor 1
chr11_-_102668879 1.27 ENST00000315274.6
MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr11_-_64900791 1.26 ENST00000531018.1
SYVN1
synovial apoptosis inhibitor 1, synoviolin
chr4_+_77870856 1.24 ENST00000264893.6
ENST00000502584.1
ENST00000510641.1
SEPT11
septin 11
chr11_-_119999539 1.24 ENST00000541857.1
TRIM29
tripartite motif containing 29
chr6_-_134499037 1.23 ENST00000528577.1
SGK1
serum/glucocorticoid regulated kinase 1
chr12_+_10124001 1.21 ENST00000396507.3
ENST00000304361.4
ENST00000434319.2
CLEC12A
C-type lectin domain family 12, member A
chr1_-_44497024 1.17 ENST00000372306.3
ENST00000372310.3
ENST00000475075.2
SLC6A9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chrX_-_106243294 1.17 ENST00000255495.7
MORC4
MORC family CW-type zinc finger 4
chr4_+_77870960 1.11 ENST00000505788.1
ENST00000510515.1
ENST00000504637.1
SEPT11
septin 11
chr6_-_32812420 1.11 ENST00000374881.2
PSMB8
proteasome (prosome, macropain) subunit, beta type, 8
chr19_-_51869592 1.11 ENST00000596253.1
ENST00000309244.4
ETFB
electron-transfer-flavoprotein, beta polypeptide
chr18_+_21464737 1.07 ENST00000586751.1
LAMA3
laminin, alpha 3
chr12_+_56390964 1.05 ENST00000356124.4
ENST00000266971.3
ENST00000394115.2
ENST00000547586.1
ENST00000552258.1
ENST00000548274.1
ENST00000546833.1
SUOX
sulfite oxidase
chr4_+_159727272 1.05 ENST00000379346.3
FNIP2
folliculin interacting protein 2
chr11_-_119999611 1.04 ENST00000529044.1
TRIM29
tripartite motif containing 29
chr17_-_38978847 1.02 ENST00000269576.5
KRT10
keratin 10
chr6_+_126102292 1.02 ENST00000368357.3
NCOA7
nuclear receptor coactivator 7
chr3_+_177159744 1.02 ENST00000439009.1
LINC00578
long intergenic non-protein coding RNA 578
chr19_-_47288162 1.02 ENST00000594991.1
SLC1A5
solute carrier family 1 (neutral amino acid transporter), member 5
chr17_+_53342311 1.00 ENST00000226067.5
HLF
hepatic leukemia factor
chr6_+_31939608 0.99 ENST00000375331.2
ENST00000375333.2
STK19
serine/threonine kinase 19
chr5_-_172756506 0.97 ENST00000265087.4
STC2
stanniocalcin 2
chr18_+_46065393 0.97 ENST00000256413.3
CTIF
CBP80/20-dependent translation initiation factor
chr16_+_56970567 0.97 ENST00000563911.1
HERPUD1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr9_+_137218362 0.96 ENST00000481739.1
RXRA
retinoid X receptor, alpha
chr14_-_25045446 0.95 ENST00000216336.2
CTSG
cathepsin G
chr12_+_10366016 0.92 ENST00000546017.1
ENST00000535576.1
ENST00000539170.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr3_+_127770455 0.92 ENST00000464451.1
SEC61A1
Sec61 alpha 1 subunit (S. cerevisiae)
chr3_+_187461442 0.92 ENST00000450760.1
RP11-211G3.2
RP11-211G3.2
chr5_+_33441053 0.91 ENST00000541634.1
ENST00000455217.2
ENST00000414361.2
TARS
threonyl-tRNA synthetase
chr18_+_72168325 0.91 ENST00000582666.1
CNDP2
CNDP dipeptidase 2 (metallopeptidase M20 family)
chr1_-_204380919 0.91 ENST00000367188.4
PPP1R15B
protein phosphatase 1, regulatory subunit 15B
chr13_-_99667960 0.90 ENST00000448493.2
DOCK9
dedicator of cytokinesis 9
chr9_+_2621798 0.89 ENST00000382100.3
VLDLR
very low density lipoprotein receptor
chr12_-_6451186 0.88 ENST00000540022.1
ENST00000536194.1
TNFRSF1A
tumor necrosis factor receptor superfamily, member 1A
chr8_-_21966893 0.87 ENST00000522405.1
ENST00000522379.1
ENST00000309188.6
ENST00000521807.2
NUDT18
nudix (nucleoside diphosphate linked moiety X)-type motif 18
chr19_-_54824344 0.87 ENST00000346508.3
ENST00000446712.3
ENST00000432233.3
ENST00000301219.3
LILRA5
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
chr12_-_12674032 0.87 ENST00000298573.4
DUSP16
dual specificity phosphatase 16
chr17_+_65374075 0.86 ENST00000581322.1
PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr4_-_70725856 0.83 ENST00000226444.3
SULT1E1
sulfotransferase family 1E, estrogen-preferring, member 1
chr16_-_4323015 0.83 ENST00000204517.6
TFAP4
transcription factor AP-4 (activating enhancer binding protein 4)
chr1_+_152784447 0.82 ENST00000360090.3
LCE1B
late cornified envelope 1B
chr10_+_45495898 0.82 ENST00000298299.3
ZNF22
zinc finger protein 22
chrX_+_24073048 0.81 ENST00000423068.1
EIF2S3
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
chr10_+_81272287 0.81 ENST00000520547.2
EIF5AL1
eukaryotic translation initiation factor 5A-like 1
chr5_+_33440802 0.80 ENST00000502553.1
ENST00000514259.1
ENST00000265112.3
TARS
threonyl-tRNA synthetase
chr11_+_118955583 0.80 ENST00000278715.3
ENST00000536813.1
ENST00000537841.1
ENST00000542729.1
ENST00000546302.1
ENST00000442944.2
ENST00000544387.1
ENST00000543090.1
HMBS
hydroxymethylbilane synthase
chr12_-_6451014 0.80 ENST00000366159.4
ENST00000539372.1
TNFRSF1A
tumor necrosis factor receptor superfamily, member 1A
chr1_-_36948879 0.78 ENST00000373106.1
ENST00000373104.1
ENST00000373103.1
CSF3R
colony stimulating factor 3 receptor (granulocyte)
chr4_+_129349188 0.78 ENST00000511497.1
RP11-420A23.1
RP11-420A23.1
chr20_+_39969519 0.76 ENST00000373257.3
LPIN3
lipin 3
chr12_-_6451235 0.76 ENST00000440083.2
ENST00000162749.2
TNFRSF1A
tumor necrosis factor receptor superfamily, member 1A
chr1_+_203595689 0.75 ENST00000357681.5
ATP2B4
ATPase, Ca++ transporting, plasma membrane 4
chr10_-_21806759 0.75 ENST00000444772.3
SKIDA1
SKI/DACH domain containing 1
chr17_+_29248918 0.73 ENST00000581548.1
ENST00000580525.1
ADAP2
ArfGAP with dual PH domains 2
chr5_+_179105615 0.73 ENST00000514383.1
CANX
calnexin
chr19_+_49258775 0.72 ENST00000593756.1
FGF21
fibroblast growth factor 21
chr5_-_137878887 0.72 ENST00000507939.1
ENST00000572514.1
ENST00000499810.2
ENST00000360541.5
ETF1
eukaryotic translation termination factor 1
chr6_+_30687978 0.72 ENST00000327892.8
ENST00000435534.1
TUBB
tubulin, beta class I
chr18_+_29027696 0.71 ENST00000257189.4
DSG3
desmoglein 3
chr2_+_216582766 0.70 ENST00000415479.1
AC093850.2
AC093850.2
chr22_-_39640756 0.69 ENST00000331163.6
PDGFB
platelet-derived growth factor beta polypeptide
chr15_-_80263506 0.68 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr4_+_159727222 0.66 ENST00000512986.1
FNIP2
folliculin interacting protein 2
chr11_+_62649158 0.66 ENST00000539891.1
ENST00000536981.1
SLC3A2
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr19_-_47287990 0.65 ENST00000593713.1
ENST00000598022.1
ENST00000434726.2
SLC1A5
solute carrier family 1 (neutral amino acid transporter), member 5
chr18_+_61420169 0.64 ENST00000425392.1
ENST00000336429.2
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr7_-_27224842 0.64 ENST00000517402.1
HOXA11
homeobox A11
chr22_+_41258250 0.62 ENST00000544094.1
XPNPEP3
X-prolyl aminopeptidase (aminopeptidase P) 3, putative
chr14_+_75894714 0.61 ENST00000559060.1
JDP2
Jun dimerization protein 2
chr1_+_203595903 0.60 ENST00000367218.3
ENST00000367219.3
ENST00000391954.2
ATP2B4
ATPase, Ca++ transporting, plasma membrane 4
chr7_-_50860565 0.59 ENST00000403097.1
GRB10
growth factor receptor-bound protein 10
chr17_+_29248953 0.58 ENST00000581285.1
ADAP2
ArfGAP with dual PH domains 2
chr12_-_57914275 0.58 ENST00000547303.1
ENST00000552740.1
ENST00000547526.1
ENST00000551116.1
ENST00000346473.3
DDIT3
DNA-damage-inducible transcript 3
chr16_+_89334512 0.56 ENST00000602042.1
AC137932.1
AC137932.1
chrX_-_109683446 0.56 ENST00000372057.1
AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr3_-_126327398 0.55 ENST00000383572.2
TXNRD3NB
thioredoxin reductase 3 neighbor
chr6_+_32812568 0.54 ENST00000414474.1
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr2_+_28618532 0.54 ENST00000545753.1
FOSL2
FOS-like antigen 2
chr7_-_27224795 0.53 ENST00000006015.3
HOXA11
homeobox A11
chrX_-_55208866 0.52 ENST00000545075.1
MTRNR2L10
MT-RNR2-like 10
chr15_+_62359175 0.52 ENST00000355522.5
C2CD4A
C2 calcium-dependent domain containing 4A
chr5_-_35230434 0.51 ENST00000504500.1
PRLR
prolactin receptor
chr14_+_75894391 0.49 ENST00000419727.2
JDP2
Jun dimerization protein 2
chr12_-_25102252 0.49 ENST00000261192.7
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr22_+_39052632 0.49 ENST00000411557.1
ENST00000396811.2
ENST00000216029.3
ENST00000416285.1
CBY1
chibby homolog 1 (Drosophila)

Network of associatons between targets according to the STRING database.

First level regulatory network of CEBPB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.7 GO:0015920 lipopolysaccharide transport(GO:0015920)
2.3 11.3 GO:1904640 response to methionine(GO:1904640)
1.6 4.8 GO:0070409 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
1.6 4.7 GO:1904237 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
1.6 7.8 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
1.5 10.6 GO:0071279 cellular response to cobalt ion(GO:0071279)
1.5 4.5 GO:2000547 regulation of dendritic cell dendrite assembly(GO:2000547)
1.4 14.1 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
1.3 4.0 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
1.3 5.1 GO:0006535 cysteine biosynthetic process from serine(GO:0006535)
1.1 2.3 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
1.1 3.3 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.9 10.4 GO:0001554 luteolysis(GO:0001554)
0.9 3.7 GO:2000230 response to metformin(GO:1901558) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.9 6.3 GO:0019557 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.9 3.6 GO:0006788 heme oxidation(GO:0006788) negative regulation of mast cell cytokine production(GO:0032764)
0.8 4.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.7 2.1 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.7 11.7 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.6 3.0 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.6 24.9 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.6 1.7 GO:0050787 antibiotic metabolic process(GO:0016999) detoxification of mercury ion(GO:0050787)
0.5 3.8 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.5 1.6 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.5 3.6 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.5 2.0 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.5 1.4 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.5 1.9 GO:0009956 radial pattern formation(GO:0009956)
0.4 1.3 GO:2000282 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) regulation of cellular amino acid biosynthetic process(GO:2000282) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.4 3.5 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.4 1.7 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.4 2.6 GO:0033133 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.4 1.7 GO:0010585 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.4 2.5 GO:0044245 polysaccharide digestion(GO:0044245)
0.4 2.5 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.3 1.0 GO:0045994 positive regulation of translational initiation by iron(GO:0045994)
0.3 6.5 GO:2000194 regulation of female gonad development(GO:2000194)
0.3 1.5 GO:0085032 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.3 0.9 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.3 2.0 GO:1903575 cornified envelope assembly(GO:1903575)
0.3 0.8 GO:0006711 estrogen catabolic process(GO:0006711)
0.3 3.6 GO:0048251 elastic fiber assembly(GO:0048251)
0.3 2.4 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.3 7.0 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.2 4.5 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.2 1.6 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.2 5.4 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.2 1.4 GO:0098886 modification of dendritic spine(GO:0098886)
0.2 1.6 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.2 0.9 GO:0045209 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.2 1.5 GO:0035992 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.2 1.7 GO:0015811 L-cystine transport(GO:0015811)
0.2 3.8 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.2 1.6 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.2 1.1 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.2 3.9 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 0.7 GO:0090678 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.2 2.9 GO:0015684 ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
0.2 0.9 GO:0039019 pronephric nephron development(GO:0039019)
0.1 0.6 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.1 1.3 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.1 1.0 GO:0070944 neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) neutrophil mediated killing of bacterium(GO:0070944)
0.1 0.8 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.1 1.3 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.6 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 0.9 GO:0034436 glycoprotein transport(GO:0034436)
0.1 2.5 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 0.3 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 1.5 GO:0006449 regulation of translational termination(GO:0006449)
0.1 0.9 GO:1903912 negative regulation of PERK-mediated unfolded protein response(GO:1903898) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.1 2.3 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 1.2 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.7 GO:0060356 leucine import(GO:0060356)
0.1 0.3 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.1 1.4 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 0.3 GO:0060264 respiratory burst involved in inflammatory response(GO:0002536) regulation of respiratory burst involved in inflammatory response(GO:0060264)
0.1 0.3 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.1 0.2 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
0.1 0.4 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.1 2.8 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.1 1.0 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 1.2 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.1 3.8 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.1 0.3 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.1 3.4 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.1 0.4 GO:0010728 positive regulation of hydrogen peroxide metabolic process(GO:0010726) regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.1 2.7 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.1 0.5 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 0.2 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.1 2.1 GO:0097186 amelogenesis(GO:0097186)
0.1 4.7 GO:0035987 endodermal cell differentiation(GO:0035987)
0.1 4.6 GO:0018149 peptide cross-linking(GO:0018149)
0.1 1.1 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 0.4 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.1 0.8 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 1.1 GO:0031065 positive regulation of histone deacetylation(GO:0031065)
0.0 5.0 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 0.8 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.3 GO:0036093 male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093)
0.0 0.2 GO:0038112 interleukin-8-mediated signaling pathway(GO:0038112)
0.0 0.6 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0 0.2 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.7 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.2 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 1.3 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 1.9 GO:0002250 adaptive immune response(GO:0002250)
0.0 1.0 GO:0016032 viral process(GO:0016032)
0.0 0.8 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.7 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.5 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.3 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 4.6 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.4 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 0.5 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.6 GO:0003094 glomerular filtration(GO:0003094) renal filtration(GO:0097205)
0.0 2.3 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.0 1.6 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.0 0.4 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 1.2 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.2 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 1.1 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.5 GO:0007420 brain development(GO:0007420)
0.0 2.4 GO:0051291 protein heterooligomerization(GO:0051291)
0.0 1.7 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.4 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.5 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 0.5 GO:0016337 single organismal cell-cell adhesion(GO:0016337)
0.0 1.3 GO:0007507 heart development(GO:0007507)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 14.1 GO:0070552 BRISC complex(GO:0070552)
1.3 3.8 GO:1990622 CHOP-ATF3 complex(GO:1990622)
1.2 3.5 GO:0005900 oncostatin-M receptor complex(GO:0005900)
1.0 4.0 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
1.0 13.4 GO:0005577 fibrinogen complex(GO:0005577)
0.6 2.5 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
0.5 10.8 GO:0043203 axon hillock(GO:0043203)
0.5 1.4 GO:0097444 spine apparatus(GO:0097444)
0.4 7.6 GO:0031089 platelet dense granule lumen(GO:0031089)
0.4 2.6 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.4 3.6 GO:0071953 elastic fiber(GO:0071953)
0.3 1.3 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.2 1.3 GO:1990037 Lewy body core(GO:1990037)
0.2 2.1 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.2 1.6 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 2.0 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 1.7 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 12.5 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 1.4 GO:0016013 syntrophin complex(GO:0016013)
0.1 3.8 GO:0042101 T cell receptor complex(GO:0042101)
0.1 1.1 GO:0005610 laminin-5 complex(GO:0005610)
0.1 9.7 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 4.8 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 2.0 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.1 2.2 GO:0005614 interstitial matrix(GO:0005614)
0.1 3.0 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 5.5 GO:0016235 aggresome(GO:0016235)
0.1 5.4 GO:0001533 cornified envelope(GO:0001533)
0.1 1.3 GO:0005915 zonula adherens(GO:0005915)
0.1 0.7 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.5 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 11.0 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.9 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 4.9 GO:0005901 caveola(GO:0005901)
0.0 0.9 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 6.2 GO:0072562 blood microparticle(GO:0072562)
0.0 15.8 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 2.8 GO:0031526 brush border membrane(GO:0031526)
0.0 5.7 GO:0032993 protein-DNA complex(GO:0032993)
0.0 5.0 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.6 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 2.7 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.5 GO:0031904 endosome lumen(GO:0031904)
0.0 0.3 GO:0030897 HOPS complex(GO:0030897)
0.0 0.0 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.0 0.3 GO:0071141 SMAD protein complex(GO:0071141)
0.0 1.3 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 1.4 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 1.7 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 2.8 GO:0055037 recycling endosome(GO:0055037)
0.0 1.9 GO:0030175 filopodium(GO:0030175)
0.0 1.9 GO:0016605 PML body(GO:0016605)
0.0 18.4 GO:0005615 extracellular space(GO:0005615)
0.0 1.5 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 9.1 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
2.1 6.3 GO:0004397 histidine ammonia-lyase activity(GO:0004397)
1.4 14.1 GO:0004793 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
1.4 4.1 GO:0008859 exoribonuclease II activity(GO:0008859)
1.3 5.1 GO:0098809 cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
1.2 4.8 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
1.1 4.5 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
1.1 7.6 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.9 3.6 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.9 7.8 GO:0032810 sterol response element binding(GO:0032810)
0.9 7.7 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.8 5.4 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.7 4.0 GO:0030492 hemoglobin binding(GO:0030492)
0.6 3.0 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.6 3.5 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.5 1.6 GO:0070538 oleic acid binding(GO:0070538)
0.5 4.7 GO:0050692 DBD domain binding(GO:0050692)
0.5 1.6 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.5 2.6 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.5 1.4 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.4 2.2 GO:0070052 collagen V binding(GO:0070052)
0.4 1.3 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.4 8.8 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.4 1.7 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.4 2.1 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.4 1.6 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.4 3.8 GO:0001849 complement component C1q binding(GO:0001849)
0.3 2.4 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.3 2.5 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.3 5.7 GO:0030957 Tat protein binding(GO:0030957)
0.3 2.0 GO:0070728 leucine binding(GO:0070728)
0.3 1.7 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.2 7.4 GO:0001848 complement binding(GO:0001848)
0.2 1.7 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.2 3.5 GO:0030280 structural constituent of epidermis(GO:0030280)
0.2 2.9 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.2 0.9 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.2 0.9 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.2 1.1 GO:0030151 molybdenum ion binding(GO:0030151)
0.2 1.7 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.2 0.9 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.2 3.6 GO:0008430 selenium binding(GO:0008430)
0.2 2.8 GO:0019957 C-C chemokine binding(GO:0019957)
0.2 2.3 GO:0070700 BMP receptor binding(GO:0070700)
0.2 2.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 2.5 GO:0004568 chitinase activity(GO:0004568)
0.1 0.8 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 0.8 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.8 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.1 1.3 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 0.3 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 6.5 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 1.4 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.1 0.7 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 1.7 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.1 1.2 GO:0008526 phosphatidylcholine transporter activity(GO:0008525) phosphatidylinositol transporter activity(GO:0008526)
0.1 15.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.5 GO:0004925 prolactin receptor activity(GO:0004925)
0.1 11.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 9.0 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 4.7 GO:0016504 peptidase activator activity(GO:0016504)
0.1 0.2 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
0.1 0.4 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 2.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 1.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 1.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 2.1 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 1.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 2.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 1.6 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 1.9 GO:0001972 retinoic acid binding(GO:0001972)
0.0 14.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.2 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.2 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.0 0.2 GO:0070012 oligopeptidase activity(GO:0070012)
0.0 1.3 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 3.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.7 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.2 GO:0019959 interleukin-8 receptor activity(GO:0004918) interleukin-8 binding(GO:0019959)
0.0 0.5 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0 0.7 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.3 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.3 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.7 GO:0051400 BH domain binding(GO:0051400)
0.0 1.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.7 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 5.9 GO:0005178 integrin binding(GO:0005178)
0.0 0.7 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 1.5 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.6 GO:0005518 collagen binding(GO:0005518)
0.0 3.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.4 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 5.0 GO:0030674 protein binding, bridging(GO:0030674)
0.0 1.0 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 2.0 GO:0051213 dioxygenase activity(GO:0051213)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.4 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.0 0.9 GO:0043022 ribosome binding(GO:0043022)
0.0 0.0 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 0.3 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 17.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.2 11.1 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.2 12.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.2 4.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 9.9 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 7.9 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 9.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 2.5 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.1 2.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 26.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 7.4 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.9 PID CD40 PATHWAY CD40/CD40L signaling
0.0 3.0 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 3.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 16.3 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.9 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.6 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 1.2 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 1.3 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.6 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.0 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.9 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.5 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.7 PID BCR 5PATHWAY BCR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 15.6 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.5 8.8 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.5 9.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.4 16.8 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.4 9.0 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.3 3.8 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.2 4.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 5.4 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.1 6.8 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 4.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 5.1 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.1 3.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 10.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 2.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 2.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 2.0 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.6 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1 5.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.9 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 1.6 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 11.9 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 2.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.7 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.6 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 7.5 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.0 0.5 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 2.6 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.7 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 1.7 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.8 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.8 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.2 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 4.4 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.5 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 1.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.3 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME AMYLOIDS Genes involved in Amyloids