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Illumina Body Map 2
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Results for CENPB
Z-value: 0.79
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Transcription factors associated with CENPB
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| CENPB | hg19_v2_chr20_-_3767324_3767443 | 0.42 | 1.7e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chrY_+_2709527 Show fit | 1.88 |
ENST00000250784.8
|
ribosomal protein S4, Y-linked 1 |
|
| chrY_+_2709906 Show fit | 1.75 |
ENST00000430575.1
|
ribosomal protein S4, Y-linked 1 |
|
| chrX_-_21676442 Show fit | 1.47 |
ENST00000379499.2
|
kelch-like family member 34 |
|
| chr6_-_105627735 Show fit | 1.32 |
ENST00000254765.3
|
popeye domain containing 3 |
|
| chrX_+_135230712 Show fit | 1.19 |
ENST00000535737.1
|
four and a half LIM domains 1 |
|
| chr17_-_46799872 Show fit | 1.15 |
ENST00000290294.3
|
prostate cancer susceptibility candidate 1 |
|
| chr6_+_27356745 Show fit | 1.09 |
ENST00000461521.1
|
zinc finger protein 391 |
|
| chr1_-_205819245 Show fit | 0.99 |
ENST00000367136.4
|
peptidase M20 domain containing 1 |
|
| chr20_-_55841398 Show fit | 0.97 |
ENST00000395864.3
|
bone morphogenetic protein 7 |
|
| chr6_+_27356497 Show fit | 0.97 |
ENST00000244576.4
|
zinc finger protein 391 |
Network of associatons between targets according to the STRING database.
First level regulatory network of CENPB
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.6 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
| 0.0 | 1.7 | GO:0046580 | negative regulation of Ras protein signal transduction(GO:0046580) |
| 0.4 | 1.5 | GO:0072134 | nephrogenic mesenchyme morphogenesis(GO:0072134) allantois development(GO:1905069) |
| 0.2 | 1.4 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
| 0.1 | 1.3 | GO:0032887 | regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846) |
| 0.0 | 1.2 | GO:0043268 | positive regulation of potassium ion transport(GO:0043268) |
| 0.2 | 1.0 | GO:0043605 | cellular amide catabolic process(GO:0043605) |
| 0.1 | 1.0 | GO:0030259 | lipid glycosylation(GO:0030259) |
| 0.0 | 1.0 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
| 0.1 | 0.8 | GO:0098881 | exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.3 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.1 | 1.7 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.0 | 1.5 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.1 | 1.3 | GO:0055028 | cortical microtubule(GO:0055028) |
| 0.2 | 0.8 | GO:1990796 | photoreceptor cell terminal bouton(GO:1990796) |
| 0.1 | 0.8 | GO:0014802 | terminal cisterna(GO:0014802) |
| 0.0 | 0.8 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.1 | 0.6 | GO:0002081 | outer acrosomal membrane(GO:0002081) |
| 0.1 | 0.6 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
| 0.1 | 0.6 | GO:0070765 | gamma-secretase complex(GO:0070765) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.6 | GO:0019843 | rRNA binding(GO:0019843) |
| 0.1 | 1.5 | GO:0070700 | BMP receptor binding(GO:0070700) |
| 0.3 | 1.4 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
| 0.1 | 1.3 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
| 0.0 | 1.3 | GO:0030552 | cAMP binding(GO:0030552) |
| 0.0 | 1.0 | GO:0008376 | acetylgalactosaminyltransferase activity(GO:0008376) |
| 0.1 | 0.8 | GO:0050544 | arachidonic acid binding(GO:0050544) |
| 0.0 | 0.8 | GO:0031698 | beta-2 adrenergic receptor binding(GO:0031698) |
| 0.0 | 0.8 | GO:0051019 | mitogen-activated protein kinase binding(GO:0051019) |
| 0.2 | 0.7 | GO:0003880 | protein C-terminal carboxyl O-methyltransferase activity(GO:0003880) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.5 | PID ALK2 PATHWAY | ALK2 signaling events |
| 0.0 | 0.8 | PID ATM PATHWAY | ATM pathway |
| 0.0 | 0.8 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.0 | 0.7 | PID S1P S1P4 PATHWAY | S1P4 pathway |
| 0.0 | 0.7 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.0 | 0.6 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.0 | 0.4 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.8 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.1 | 1.4 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.0 | 1.3 | REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
| 0.0 | 0.8 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.0 | 0.8 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.0 | 0.7 | REACTOME G PROTEIN ACTIVATION | Genes involved in G-protein activation |
| 0.0 | 0.6 | REACTOME REGULATED PROTEOLYSIS OF P75NTR | Genes involved in Regulated proteolysis of p75NTR |
| 0.0 | 0.5 | REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE | Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle |
| 0.0 | 0.4 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 0.0 | 0.4 | REACTOME P38MAPK EVENTS | Genes involved in p38MAPK events |