ISMARA results: CTCF

Project

Illumina Body Map 2

Navigation

Downloads

Results for CTCF_CTCFL

Z-value: 1.08

Motif logo

Transcription factors associated with CTCF_CTCFL

Gene Symbol	Gene ID	Gene Info
CTCF Ensembl NCBI GeneCards UniProt NextProt	ENSG00000102974.10	CCCTC-binding factor
CTCFL Ensembl NCBI GeneCards UniProt NextProt	ENSG00000124092.8	CCCTC-binding factor like

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
CTCF	hg19_v2_chr16_+_67596310_67596353	0.58	4.8e-04	Click!
CTCFL	hg19_v2_chr20_-_56100155_56100163	0.52	2.3e-03	Click!

Activity profile of CTCF_CTCFL motif

Sorted Z-values of CTCF_CTCFL motif

Top targets:

Search:

Show entries

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr2_+_114737146 Show fit	5.55	ENST00000412690.1	AC010982.1 Ensembl NCBI GeneCards UniProt NextProt Show fit	AC010982.1
chr2_+_114737472 Show fit	3.29	ENST00000420161.1	AC110769.3 Ensembl NCBI GeneCards UniProt NextProt Show fit	AC110769.3
chr1_-_109655377 Show fit	3.05	ENST00000369948.3	C1orf194 Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 1 open reading frame 194
chr1_-_109655355 Show fit	2.86	ENST00000369945.3	C1orf194 Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 1 open reading frame 194
chr11_+_61520075 Show fit	2.85	ENST00000278836.5	MYRF Ensembl NCBI GeneCards UniProt NextProt Show fit	myelin regulatory factor
chr15_+_45722727 Show fit	2.66	ENST00000396650.2 ENST00000558435.1 ENST00000344300.3	C15orf48 Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 15 open reading frame 48
chr4_-_44450814 Show fit	2.57	ENST00000360029.3	KCTD8 Ensembl NCBI GeneCards UniProt NextProt Show fit	potassium channel tetramerization domain containing 8
chr1_-_156390128 Show fit	2.46	ENST00000368242.3	C1orf61 Ensembl NCBI GeneCards UniProt NextProt Show fit	chromosome 1 open reading frame 61
chr2_-_154335300 Show fit	2.43	ENST00000325926.3	RPRM Ensembl NCBI GeneCards UniProt NextProt Show fit	reprimo, TP53 dependent G2 arrest mediator candidate
chr11_-_64490634 Show fit	2.37	ENST00000377559.3 ENST00000265459.6	NRXN2 Ensembl NCBI GeneCards UniProt NextProt Show fit	neurexin 2

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of CTCF_CTCFL

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.3	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	3.8	GO:0060997	dendritic spine morphogenesis(GO:0060997)
0.2	2.9	GO:0032286	central nervous system myelin maintenance(GO:0032286)
0.2	2.8	GO:0098887	neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887)
0.0	2.7	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.2	2.6	GO:0090394	negative regulation of excitatory postsynaptic potential(GO:0090394)
0.4	2.5	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.4	2.5	GO:0044026	DNA hypermethylation(GO:0044026)
0.0	2.5	GO:0086010	membrane depolarization during action potential(GO:0086010)
0.3	2.4	GO:0097116	gephyrin clustering involved in postsynaptic density assembly(GO:0097116)

Showing 1 to 10 of 249 entries

Gene overrepresentation in cellular_component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.4	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.0	4.1	GO:0042734	presynaptic membrane(GO:0042734)
0.1	3.4	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.2	3.0	GO:0097418	neurofibrillary tangle(GO:0097418)
0.0	3.0	GO:0001917	photoreceptor inner segment(GO:0001917)
0.1	2.7	GO:0097381	photoreceptor disc membrane(GO:0097381)
0.0	2.6	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
0.1	2.5	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	2.4	GO:0097014	axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.3	2.3	GO:0098845	postsynaptic endosome(GO:0098845)

Showing 1 to 10 of 107 entries

Gene overrepresentation in molecular_function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	6.5	GO:0005096	GTPase activator activity(GO:0005096)
0.1	5.2	GO:1905030	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1	4.5	GO:0070840	dynein complex binding(GO:0070840)
0.1	4.5	GO:0042974	retinoic acid receptor binding(GO:0042974)
0.0	4.3	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.1	2.7	GO:0017091	AU-rich element binding(GO:0017091)
0.0	2.7	GO:0004984	olfactory receptor activity(GO:0004984)
0.3	2.6	GO:1904929	coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.1	2.4	GO:0097109	neuroligin family protein binding(GO:0097109)
0.3	2.3	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)

Showing 1 to 10 of 149 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	4.3	PID RAS PATHWAY	Regulation of Ras family activation
0.1	3.2	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.1	2.7	PID CONE PATHWAY	Visual signal transduction: Cones
0.0	1.9	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	1.8	PID FANCONI PATHWAY	Fanconi anemia pathway
0.0	1.4	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	1.4	PID ENDOTHELIN PATHWAY	Endothelins
0.1	1.3	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	1.1	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	1.1	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.

Showing 1 to 10 of 22 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.4	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.1	3.1	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	3.1	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	3.0	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	2.6	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	2.3	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.1	2.2	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	2.1	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	2.0	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
0.1	1.9	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors

Showing 1 to 10 of 34 entries

Results for CTCF_CTCFL

Z-value: 1.08

Motif logo

Transcription factors associated with CTCF_CTCFL

Activity-expression correlation:

Activity profile of CTCF_CTCFL motif

Sorted Z-values of CTCF_CTCFL motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of CTCF_CTCFL

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: