ISMARA results: CUUUGGU

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Illumina Body Map 2

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Results for CUUUGGU

Z-value: 1.04

Motif logo

miRNA associated with seed CUUUGGU

Name	miRBASE accession
hsa-miR-9-5p miRBase	MIMAT0000441

Activity profile of CUUUGGU motif

Sorted Z-values of CUUUGGU motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr2_-_1748214 Show fit	2.18	ENST00000433670.1 ENST00000425171.1 ENST00000252804.4	PXDN Ensembl NCBI GeneCards UniProt NextProt Show fit	peroxidasin homolog (Drosophila)
chr21_-_44846999 Show fit	1.99	ENST00000270162.6	SIK1 Ensembl NCBI GeneCards UniProt NextProt Show fit	salt-inducible kinase 1
chr4_+_111397216 Show fit	1.91	ENST00000265162.5	ENPEP Ensembl NCBI GeneCards UniProt NextProt Show fit	glutamyl aminopeptidase (aminopeptidase A)
chr11_+_69924397 Show fit	1.87	ENST00000355303.5	ANO1 Ensembl NCBI GeneCards UniProt NextProt Show fit	anoctamin 1, calcium activated chloride channel
chr21_-_28338732 Show fit	1.85	ENST00000284987.5	ADAMTS5 Ensembl NCBI GeneCards UniProt NextProt Show fit	ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr17_-_1395954 Show fit	1.83	ENST00000359786.5	MYO1C Ensembl NCBI GeneCards UniProt NextProt Show fit	myosin IC
chr7_-_27224795 Show fit	1.82	ENST00000006015.3	HOXA11 Ensembl NCBI GeneCards UniProt NextProt Show fit	homeobox A11
chr17_+_12569306 Show fit	1.79	ENST00000425538.1	MYOCD Ensembl NCBI GeneCards UniProt NextProt Show fit	myocardin
chr7_-_45960850 Show fit	1.78	ENST00000381083.4 ENST00000381086.5 ENST00000275521.6	IGFBP3 Ensembl NCBI GeneCards UniProt NextProt Show fit	insulin-like growth factor binding protein 3
chr3_+_30648066 Show fit	1.75	ENST00000359013.4	TGFBR2 Ensembl NCBI GeneCards UniProt NextProt Show fit	transforming growth factor, beta receptor II (70/80kDa)

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of CUUUGGU

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.8	GO:0072498	embryonic skeletal joint development(GO:0072498)
0.7	2.2	GO:0060279	positive regulation of ovulation(GO:0060279)
0.1	2.2	GO:0042744	hydrogen peroxide catabolic process(GO:0042744)
0.4	2.1	GO:0060447	bud outgrowth involved in lung branching(GO:0060447)
0.4	2.1	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.4	2.0	GO:0032792	negative regulation of CREB transcription factor activity(GO:0032792)
0.1	2.0	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.5	1.9	GO:0044691	tooth eruption(GO:0044691)
0.2	1.9	GO:0002005	angiotensin catabolic process in blood(GO:0002005)
0.1	1.9	GO:0015705	iodide transport(GO:0015705)

Showing 1 to 10 of 259 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	6.4	GO:0005667	transcription factor complex(GO:0005667)
0.0	4.9	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	3.9	GO:0043296	apical junction complex(GO:0043296)
0.0	3.8	GO:0005903	brush border(GO:0005903)
0.0	3.2	GO:0005796	Golgi lumen(GO:0005796)
0.3	3.0	GO:0042567	insulin-like growth factor ternary complex(GO:0042567)
0.2	2.5	GO:0098651	basement membrane collagen trimer(GO:0098651)
0.2	2.5	GO:0002116	semaphorin receptor complex(GO:0002116)
0.0	2.1	GO:0005604	basement membrane(GO:0005604)
0.5	1.8	GO:0045160	myosin I complex(GO:0045160)

Showing 1 to 10 of 96 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	3.2	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	3.1	GO:0050840	extracellular matrix binding(GO:0050840)
0.1	2.7	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.9	2.6	GO:0004119	cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.1	2.5	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.1	2.3	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.4	2.2	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.0	2.1	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.2	1.9	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
0.1	1.9	GO:0008140	cAMP response element binding protein binding(GO:0008140)

Showing 1 to 10 of 172 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	6.5	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.1	4.5	NABA COLLAGENS	Genes encoding collagen proteins
0.0	4.3	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.1	3.3	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	3.1	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	2.2	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	2.2	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	1.9	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.0	1.8	PID P53 REGULATION PATHWAY	p53 pathway
0.0	1.8	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway

Showing 1 to 10 of 37 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	4.6	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.1	3.8	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	3.4	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	2.7	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.2	2.2	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	2.2	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	2.2	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	2.0	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	1.9	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	1.9	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions

Showing 1 to 10 of 67 entries

Results for CUUUGGU

Z-value: 1.04

Motif logo

miRNA associated with seed CUUUGGU

Activity profile of CUUUGGU motif

Sorted Z-values of CUUUGGU motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of CUUUGGU

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: