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Illumina Body Map 2
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Results for DBP
Z-value: 1.32
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Transcription factors associated with DBP
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| DBP | hg19_v2_chr19_-_49140609_49140643 | -0.43 | 1.5e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr2_-_88427568 Show fit | 5.47 |
ENST00000393750.3
ENST00000295834.3 |
fatty acid binding protein 1, liver |
|
| chr2_-_180610767 Show fit | 5.10 |
ENST00000409343.1
|
zinc finger protein 385B |
|
| chr20_-_14318248 Show fit | 4.69 |
ENST00000378053.3
ENST00000341420.4 |
fibronectin leucine rich transmembrane protein 3 |
|
| chr4_-_176733377 Show fit | 4.35 |
ENST00000505375.1
|
glycoprotein M6A |
|
| chr8_+_85618155 Show fit | 3.74 |
ENST00000523850.1
ENST00000521376.1 |
RALY RNA binding protein-like |
|
| chr2_+_234602305 Show fit | 3.37 |
ENST00000406651.1
|
UDP glucuronosyltransferase 1 family, polypeptide A6 |
|
| chrX_-_10851762 Show fit | 3.29 |
ENST00000380785.1
ENST00000380787.1 |
midline 1 (Opitz/BBB syndrome) |
|
| chr6_-_94129244 Show fit | 3.24 |
ENST00000369303.4
ENST00000369297.1 |
EPH receptor A7 |
|
| chr8_+_99076509 Show fit | 3.04 |
ENST00000318528.3
|
chromosome 8 open reading frame 47 |
|
| chr1_+_154540246 Show fit | 2.95 |
ENST00000368476.3
|
cholinergic receptor, nicotinic, beta 2 (neuronal) |
Network of associatons between targets according to the STRING database.
First level regulatory network of DBP
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 8.6 | GO:0001578 | microtubule bundle formation(GO:0001578) |
| 0.3 | 7.1 | GO:0071420 | cellular response to histamine(GO:0071420) |
| 0.1 | 7.0 | GO:0051491 | positive regulation of filopodium assembly(GO:0051491) |
| 0.5 | 6.0 | GO:0052697 | flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697) |
| 0.3 | 5.5 | GO:0032000 | positive regulation of fatty acid beta-oxidation(GO:0032000) |
| 0.3 | 5.4 | GO:0003344 | pericardium morphogenesis(GO:0003344) |
| 0.0 | 5.4 | GO:0072332 | intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332) |
| 0.2 | 4.3 | GO:0030502 | negative regulation of bone mineralization(GO:0030502) |
| 0.3 | 4.1 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 0.1 | 4.1 | GO:0050999 | regulation of nitric-oxide synthase activity(GO:0050999) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 12.0 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.3 | 11.0 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.8 | 8.6 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.2 | 8.3 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
| 0.0 | 6.3 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.3 | 5.5 | GO:0045179 | apical cortex(GO:0045179) |
| 0.0 | 5.2 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 4.9 | GO:0044291 | cell-cell contact zone(GO:0044291) |
| 0.1 | 4.4 | GO:0097440 | apical dendrite(GO:0097440) |
| 0.0 | 4.2 | GO:0030018 | Z disc(GO:0030018) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 9.1 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.1 | 6.7 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.4 | 5.7 | GO:0008503 | benzodiazepine receptor activity(GO:0008503) |
| 0.8 | 5.5 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
| 0.0 | 5.4 | GO:0002039 | p53 binding(GO:0002039) |
| 0.1 | 4.7 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.7 | 4.3 | GO:1990430 | extracellular matrix protein binding(GO:1990430) |
| 0.2 | 4.2 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.3 | 4.1 | GO:0016909 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
| 0.4 | 4.0 | GO:0060072 | large conductance calcium-activated potassium channel activity(GO:0060072) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 7.9 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.1 | 6.8 | SIG CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.0 | 5.5 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.0 | 4.8 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.1 | 3.8 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.0 | 3.6 | PID BMP PATHWAY | BMP receptor signaling |
| 0.0 | 2.9 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.0 | 2.8 | PID P73PATHWAY | p73 transcription factor network |
| 0.1 | 2.7 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.1 | 2.5 | PID LYMPH ANGIOGENESIS PATHWAY | VEGFR3 signaling in lymphatic endothelium |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 8.3 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.2 | 6.0 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.0 | 5.9 | REACTOME PPARA ACTIVATES GENE EXPRESSION | Genes involved in PPARA Activates Gene Expression |
| 0.2 | 4.8 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.1 | 4.3 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.1 | 4.1 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.1 | 4.1 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.1 | 3.8 | REACTOME ENOS ACTIVATION AND REGULATION | Genes involved in eNOS activation and regulation |
| 0.1 | 3.5 | REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS | Genes involved in p130Cas linkage to MAPK signaling for integrins |
| 0.0 | 3.5 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |