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Illumina Body Map 2

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Results for DDIT3

Z-value: 0.87

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Transcription factors associated with DDIT3

Gene Symbol Gene ID Gene Info
ENSG00000175197.6 DNA damage inducible transcript 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
DDIT3hg19_v2_chr12_-_57914275_57914304-0.251.6e-01Click!

Activity profile of DDIT3 motif

Sorted Z-values of DDIT3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_92681033 4.37 ENST00000371697.3
ankyrin repeat domain 1 (cardiac muscle)
chr2_-_179672142 4.13 ENST00000342992.6
ENST00000360870.5
ENST00000460472.2
ENST00000589042.1
ENST00000591111.1
ENST00000342175.6
ENST00000359218.5
titin
chr10_-_116444371 2.30 ENST00000533213.2
ENST00000369252.4
actin binding LIM protein 1
chr15_+_85923797 1.71 ENST00000559362.1
A kinase (PRKA) anchor protein 13
chr14_+_32798547 1.70 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
A kinase (PRKA) anchor protein 6
chr14_+_32798462 1.61 ENST00000280979.4
A kinase (PRKA) anchor protein 6
chr22_+_31518938 1.60 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
inositol polyphosphate-5-phosphatase J
chr7_+_80255472 1.55 ENST00000428497.1
CD36 molecule (thrombospondin receptor)
chr2_+_63816126 1.46 ENST00000454035.1
malate dehydrogenase 1, NAD (soluble)
chr5_-_178017355 1.44 ENST00000390654.3
collagen, type XXIII, alpha 1
chr10_-_17659357 1.43 ENST00000326961.6
ENST00000361271.3
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr15_+_85923856 1.35 ENST00000560302.1
ENST00000394518.2
ENST00000361243.2
ENST00000560256.1
A kinase (PRKA) anchor protein 13
chr2_+_63816269 1.33 ENST00000432309.1
malate dehydrogenase 1, NAD (soluble)
chr3_+_157154578 1.32 ENST00000295927.3
pentraxin 3, long
chr2_-_40680578 1.29 ENST00000455476.1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr10_-_17659234 1.25 ENST00000466335.1
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr17_+_4855053 1.19 ENST00000518175.1
enolase 3 (beta, muscle)
chr2_+_63816295 1.16 ENST00000539945.1
ENST00000544381.1
malate dehydrogenase 1, NAD (soluble)
chr2_+_7118755 1.14 ENST00000433456.1
ring finger protein 144A
chr2_+_63816087 1.12 ENST00000409908.1
ENST00000442225.1
ENST00000409476.1
ENST00000436321.1
malate dehydrogenase 1, NAD (soluble)
chr6_+_144606817 1.08 ENST00000433557.1
utrophin
chr1_+_150954493 1.04 ENST00000368947.4
annexin A9
chr12_+_32638897 1.03 ENST00000531134.1
FYVE, RhoGEF and PH domain containing 4
chr1_+_111770294 1.01 ENST00000474304.2
chitinase 3-like 2
chr14_+_21387491 0.96 ENST00000258817.2
RP11-84C10.2
chr1_+_111770278 0.96 ENST00000369748.4
chitinase 3-like 2
chr15_-_64126084 0.94 ENST00000560316.1
ENST00000443617.2
ENST00000560462.1
ENST00000558532.1
ENST00000561400.1
HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
chr1_+_111770232 0.92 ENST00000369744.2
chitinase 3-like 2
chr14_+_64565442 0.91 ENST00000553308.1
spectrin repeat containing, nuclear envelope 2
chr15_-_83837983 0.79 ENST00000562702.1
Hepatoma-derived growth factor-related protein 3
chr2_+_223289208 0.78 ENST00000321276.7
sphingosine-1-phosphate phosphatase 2
chr7_-_44530479 0.78 ENST00000355451.7
NudC domain containing 3
chr4_+_6784358 0.77 ENST00000508423.1
KIAA0232
chr10_+_60028818 0.77 ENST00000333926.5
CDGSH iron sulfur domain 1
chr18_-_55288973 0.75 ENST00000423481.2
ENST00000587194.1
ENST00000591599.1
ENST00000588661.1
asparaginyl-tRNA synthetase
chr5_+_112074029 0.74 ENST00000512211.2
adenomatous polyposis coli
chr4_+_6784401 0.73 ENST00000425103.1
ENST00000307659.5
KIAA0232
chr1_+_169079823 0.71 ENST00000367813.3
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr2_-_63815860 0.71 ENST00000272321.7
ENST00000431065.1
WD repeat containing planar cell polarity effector
chr2_-_183106641 0.70 ENST00000346717.4
phosphodiesterase 1A, calmodulin-dependent
chr6_-_86353510 0.69 ENST00000444272.1
synaptotagmin binding, cytoplasmic RNA interacting protein
chrX_+_149867681 0.67 ENST00000438018.1
ENST00000436701.1
myotubularin related protein 1
chr1_+_174844645 0.66 ENST00000486220.1
RAB GTPase activating protein 1-like
chr9_+_112542591 0.65 ENST00000483909.1
ENST00000314527.4
ENST00000413420.1
ENST00000302798.7
ENST00000555236.1
ENST00000510514.5
paralemmin 2
PALM2-AKAP2 readthrough
A kinase (PRKA) anchor protein 2
chr19_-_35992780 0.64 ENST00000593342.1
ENST00000601650.1
ENST00000408915.2
dermokine
chr14_+_102276132 0.63 ENST00000350249.3
ENST00000557621.1
ENST00000556946.1
protein phosphatase 2, regulatory subunit B', gamma
chr5_-_131630931 0.60 ENST00000431054.1
prolyl 4-hydroxylase, alpha polypeptide II
chr5_+_154135029 0.57 ENST00000518297.1
La ribonucleoprotein domain family, member 1
chr1_+_90308981 0.56 ENST00000527156.1
leucine rich repeat containing 8 family, member D
chr17_+_30594823 0.56 ENST00000536287.1
rhomboid, veinlet-like 3 (Drosophila)
chr8_+_26435915 0.56 ENST00000523027.1
dihydropyrimidinase-like 2
chr12_-_25101920 0.55 ENST00000539780.1
ENST00000546285.1
ENST00000342945.5
branched chain amino-acid transaminase 1, cytosolic
chr8_-_93029520 0.54 ENST00000521553.1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr20_+_54987305 0.53 ENST00000371336.3
ENST00000434344.1
Cas scaffolding protein family member 4
chr3_-_9595480 0.52 ENST00000287585.6
lipoma HMGIC fusion partner-like 4
chr11_+_34073269 0.51 ENST00000389645.3
cell cycle associated protein 1
chr22_-_27456361 0.50 ENST00000453934.1
CTA-992D9.6
chr13_-_24007815 0.49 ENST00000382298.3
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr1_+_149804218 0.46 ENST00000610125.1
histone cluster 2, H4a
chr12_-_12491608 0.46 ENST00000545735.1
MANSC domain containing 1
chr20_+_54987168 0.45 ENST00000360314.3
Cas scaffolding protein family member 4
chr9_-_95055956 0.45 ENST00000375629.3
ENST00000447699.2
ENST00000375643.3
ENST00000395554.3
isoleucyl-tRNA synthetase
chr10_+_102756800 0.43 ENST00000370223.3
leucine zipper, putative tumor suppressor 2
chr6_+_80341000 0.41 ENST00000369838.4
SH3 domain binding glutamic acid-rich protein like 2
chr12_-_53074182 0.41 ENST00000252244.3
keratin 1
chr4_+_141178440 0.41 ENST00000394205.3
short coiled-coil protein
chr16_-_18908196 0.40 ENST00000565324.1
ENST00000561947.1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr3_+_38017264 0.40 ENST00000436654.1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr14_+_102276192 0.39 ENST00000557714.1
protein phosphatase 2, regulatory subunit B', gamma
chr12_-_52867569 0.38 ENST00000252250.6
keratin 6C
chr19_+_10736183 0.37 ENST00000590857.1
ENST00000588688.1
ENST00000586078.1
solute carrier family 44 (choline transporter), member 2
chr9_+_112542572 0.37 ENST00000374530.3
PALM2-AKAP2 readthrough
chr2_+_68872954 0.36 ENST00000394342.2
prokineticin receptor 1
chr5_+_118812237 0.35 ENST00000513628.1
hydroxysteroid (17-beta) dehydrogenase 4
chr15_+_77861183 0.34 ENST00000560590.1
ENST00000561123.1
RP11-307C19.2
chr11_-_10315741 0.33 ENST00000256190.8
SET binding factor 2
chr15_+_59730348 0.33 ENST00000288228.5
ENST00000559628.1
ENST00000557914.1
ENST00000560474.1
family with sequence similarity 81, member A
chr2_-_63815628 0.33 ENST00000409562.3
WD repeat containing planar cell polarity effector
chr9_+_70971815 0.33 ENST00000396392.1
ENST00000396396.1
phosphoglucomutase 5
chr12_-_7899935 0.33 ENST00000543765.1
C-type lectin domain family 4, member C
chr1_-_149832704 0.33 ENST00000392933.1
ENST00000369157.2
ENST00000392932.4
histone cluster 2, H4b
chr22_+_17956618 0.32 ENST00000262608.8
cat eye syndrome chromosome region, candidate 2
chr1_+_152815327 0.32 ENST00000431011.2
late cornified envelope 6A
chr14_+_21387508 0.32 ENST00000555624.1
RP11-84C10.2
chr17_-_47925379 0.31 ENST00000352793.2
ENST00000334568.4
ENST00000398154.1
ENST00000436235.1
ENST00000326219.5
tachykinin 4 (hemokinin)
chr8_-_18744528 0.31 ENST00000523619.1
pleckstrin and Sec7 domain containing 3
chr6_-_157744531 0.31 ENST00000400788.4
ENST00000367144.4
transmembrane protein 242
chr12_-_95774672 0.31 ENST00000549961.1
Uncharacterized protein
chr8_-_21669826 0.31 ENST00000517328.1
GDNF family receptor alpha 2
chr1_-_152196669 0.31 ENST00000368801.2
hornerin
chr5_+_145583107 0.30 ENST00000506502.1
RNA binding motif protein 27
chr21_-_46334186 0.30 ENST00000522931.1
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr5_+_72143988 0.30 ENST00000506351.2
transportin 1
chr4_+_157997209 0.30 ENST00000264428.4
glycine receptor, beta
chr12_-_25102252 0.29 ENST00000261192.7
branched chain amino-acid transaminase 1, cytosolic
chr10_+_86004802 0.29 ENST00000359452.4
ENST00000358110.5
ENST00000372092.3
retinal G protein coupled receptor
chr7_-_99006443 0.29 ENST00000350498.3
PDGFA associated protein 1
chr10_-_103874692 0.29 ENST00000361198.5
LIM domain binding 1
chr9_+_110045418 0.29 ENST00000419616.1
RAD23 homolog B (S. cerevisiae)
chr5_+_118812294 0.29 ENST00000509514.1
hydroxysteroid (17-beta) dehydrogenase 4
chr6_-_48036363 0.28 ENST00000543600.1
ENST00000398738.2
ENST00000339488.4
patched domain containing 4
chr17_-_2117600 0.27 ENST00000572369.1
SMG6 nonsense mediated mRNA decay factor
chr9_-_95056010 0.27 ENST00000443024.2
isoleucyl-tRNA synthetase
chr17_+_4336955 0.25 ENST00000355530.2
spinster homolog 3 (Drosophila)
chr3_+_130569429 0.24 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATPase, Ca++ transporting, type 2C, member 1
chr1_-_44820880 0.24 ENST00000372257.2
ENST00000457571.1
ENST00000452396.1
ERI1 exoribonuclease family member 3
chr8_-_82645082 0.23 ENST00000523361.1
zinc finger, AN1-type domain 1
chr20_-_60294804 0.23 ENST00000317652.1
Uncharacterized protein
chr12_+_64798826 0.22 ENST00000540203.1
exportin, tRNA
chr1_-_161277210 0.21 ENST00000491222.2
myelin protein zero
chr4_+_157997273 0.21 ENST00000541722.1
ENST00000512619.1
glycine receptor, beta
chr12_-_63328817 0.21 ENST00000228705.6
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr14_+_22265444 0.21 ENST00000390430.2
T cell receptor alpha variable 8-1
chr7_-_130597935 0.20 ENST00000447307.1
ENST00000418546.1
microRNA 29a
chr2_-_159313214 0.20 ENST00000409889.1
ENST00000283233.5
ENST00000536771.1
coiled-coil domain containing 148
chr11_+_20044096 0.19 ENST00000533917.1
neuron navigator 2
chrX_-_40506766 0.19 ENST00000378421.1
ENST00000440784.2
ENST00000327877.5
ENST00000378426.1
ENST00000378418.2
chromosome X open reading frame 38
chr19_+_1450112 0.19 ENST00000590469.1
ENST00000233607.2
ENST00000238483.4
ENST00000590877.1
adenomatosis polyposis coli 2
chr7_+_18329712 0.19 ENST00000433709.2
histone deacetylase 9
chr17_+_4337199 0.18 ENST00000333476.2
spinster homolog 3 (Drosophila)
chr3_+_12392971 0.18 ENST00000287820.6
peroxisome proliferator-activated receptor gamma
chr11_-_33913708 0.18 ENST00000257818.2
LIM domain only 2 (rhombotin-like 1)
chr9_-_124991124 0.18 ENST00000394319.4
ENST00000340587.3
LIM homeobox 6
chr16_+_56970567 0.18 ENST00000563911.1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr14_-_23446021 0.17 ENST00000553592.1
ajuba LIM protein
chr9_+_125486269 0.17 ENST00000259466.1
olfactory receptor, family 1, subfamily L, member 4
chr19_+_33865218 0.17 ENST00000585933.2
CCAAT/enhancer binding protein (C/EBP), gamma
chr1_-_20250110 0.17 ENST00000375116.3
phospholipase A2, group IIE
chr5_-_137878887 0.16 ENST00000507939.1
ENST00000572514.1
ENST00000499810.2
ENST00000360541.5
eukaryotic translation termination factor 1
chr4_-_2935674 0.16 ENST00000514800.1
major facilitator superfamily domain containing 10
chr7_+_18536090 0.16 ENST00000441986.1
histone deacetylase 9
chr8_-_93029865 0.15 ENST00000422361.2
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr17_+_56316054 0.13 ENST00000581008.1
lactoperoxidase
chr3_+_136676707 0.13 ENST00000329582.4
interleukin 20 receptor beta
chr11_+_62495541 0.13 ENST00000530625.1
ENST00000513247.2
tetratricopeptide repeat domain 9C
chr1_+_154229547 0.13 ENST00000428595.1
ubiquitin associated protein 2-like
chr11_-_104972158 0.12 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
caspase 1, apoptosis-related cysteine peptidase
caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr1_+_114447763 0.11 ENST00000369563.3
DNA cross-link repair 1B
chr6_+_168399772 0.11 ENST00000443060.2
kinesin family member 25
chr1_-_114447683 0.09 ENST00000256658.4
ENST00000369564.1
adaptor-related protein complex 4, beta 1 subunit
chr5_+_145583156 0.09 ENST00000265271.5
RNA binding motif protein 27
chr4_-_99578789 0.09 ENST00000511651.1
ENST00000505184.1
tetraspanin 5
chr1_-_114447412 0.08 ENST00000369567.1
ENST00000369566.3
adaptor-related protein complex 4, beta 1 subunit
chr7_-_56101826 0.08 ENST00000421626.1
phosphoserine phosphatase
chr2_-_32390801 0.08 ENST00000608489.1
RP11-563N4.1
chr1_+_222910625 0.08 ENST00000360827.2
family with sequence similarity 177, member B
chr14_-_23446003 0.07 ENST00000553911.1
ajuba LIM protein
chr2_+_227700652 0.07 ENST00000341329.3
ENST00000392062.2
ENST00000437454.1
ENST00000443477.1
ENST00000423616.1
ENST00000448992.1
rhomboid domain containing 1
chr2_-_101925055 0.06 ENST00000295317.3
ring finger protein 149
chr14_+_22362613 0.06 ENST00000390438.2
T cell receptor alpha variable 8-4
chr7_+_44040488 0.06 ENST00000258704.3
speedy/RINGO cell cycle regulator family member E1
chr9_-_107361788 0.05 ENST00000374779.2
olfactory receptor, family 13, subfamily C, member 5
chr12_-_7899958 0.05 ENST00000360345.3
C-type lectin domain family 4, member C
chr17_-_30228678 0.05 ENST00000261708.4
UTP6, small subunit (SSU) processome component, homolog (yeast)
chr7_+_90338547 0.04 ENST00000446790.1
cyclin-dependent kinase 14
chr13_+_24844979 0.02 ENST00000454083.1
spermatogenesis associated 13
chr10_+_103986085 0.02 ENST00000370005.3
ELOVL fatty acid elongase 3
chr16_-_70323422 0.02 ENST00000261772.8
alanyl-tRNA synthetase
chr20_+_5987890 0.02 ENST00000378868.4
cardiolipin synthase 1
chr9_-_77502636 0.02 ENST00000449912.2
transient receptor potential cation channel, subfamily M, member 6
chr4_+_19457034 0.01 ENST00000511431.1
RP11-608O21.1
chr19_+_49258775 0.00 ENST00000593756.1
fibroblast growth factor 21

Network of associatons between targets according to the STRING database.

First level regulatory network of DDIT3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.1 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.5 3.1 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.4 3.3 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.3 5.1 GO:0006108 malate metabolic process(GO:0006108)
0.2 1.3 GO:0052199 negative regulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052199)
0.2 0.8 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.2 0.7 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.2 0.7 GO:1903281 positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.2 1.0 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.2 2.9 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.2 4.4 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.1 0.8 GO:0009099 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.1 1.6 GO:0072564 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1 1.3 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 0.1 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 0.6 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.1 0.5 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
0.1 0.9 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 0.6 GO:0072752 cellular response to rapamycin(GO:0072752)
0.1 0.6 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.7 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.1 1.2 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1 1.1 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.7 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 2.3 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.2 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0 0.3 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.0 0.3 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.8 GO:0006670 sphingosine metabolic process(GO:0006670)
0.0 0.1 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.0 0.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.4 GO:0090520 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.4 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.6 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.4 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.1 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.0 0.4 GO:0015871 choline transport(GO:0015871)
0.0 0.2 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.2 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.3 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 0.3 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.5 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.8 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 2.6 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 1.2 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.0 0.3 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.1 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.3 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.8 GO:0031114 negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.2 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.3 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.2 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.3 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.3 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.2 0.5 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
0.1 1.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.3 GO:0036457 keratohyalin granule(GO:0036457)
0.1 0.7 GO:0097452 GAIT complex(GO:0097452)
0.1 3.9 GO:0005859 muscle myosin complex(GO:0005859)
0.1 1.1 GO:0070938 contractile ring(GO:0070938)
0.1 0.3 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.5 GO:0070852 cell body fiber(GO:0070852)
0.0 0.9 GO:0016342 catenin complex(GO:0016342)
0.0 0.3 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 1.6 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.6 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.7 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.9 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 1.0 GO:0044447 axoneme part(GO:0044447)
0.0 2.9 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.7 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.8 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 3.1 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 1.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0031010 ISWI-type complex(GO:0031010)
0.0 4.4 GO:0001650 fibrillar center(GO:0001650)
0.0 2.6 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.1 GO:0072558 NLRP1 inflammasome complex(GO:0072558) protease inhibitor complex(GO:0097179)
0.0 5.3 GO:0043209 myelin sheath(GO:0043209)
0.0 1.3 GO:1904724 tertiary granule lumen(GO:1904724)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.4 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
1.3 5.1 GO:0047860 diiodophenylpyruvate reductase activity(GO:0047860)
0.3 4.1 GO:0031433 telethonin binding(GO:0031433)
0.2 3.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.2 1.3 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.2 0.7 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.2 2.9 GO:0004568 chitinase activity(GO:0004568)
0.2 3.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 1.6 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.8 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 1.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 1.3 GO:0001849 complement component C1q binding(GO:0001849)
0.1 1.6 GO:0052658 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.1 0.6 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.6 GO:0033989 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.1 0.7 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.5 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.4 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 0.6 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.3 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.4 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.0 0.7 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.4 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.3 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 1.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.0 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.0 0.7 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 1.1 GO:0017166 vinculin binding(GO:0017166)
0.0 0.7 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.4 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.6 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.3 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.0 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.8 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.6 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.0 1.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.7 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.5 GO:0070628 proteasome binding(GO:0070628)
0.0 0.2 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.8 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.1 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 3.1 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 1.4 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.7 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.3 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 2.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.8 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 2.3 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 3.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.3 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.6 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 5.7 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.8 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 0.0 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.7 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 1.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.7 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.5 REACTOME ION CHANNEL TRANSPORT Genes involved in Ion channel transport
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)