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Illumina Body Map 2

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Results for DMBX1

Z-value: 0.64

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Transcription factors associated with DMBX1

Gene Symbol Gene ID Gene Info
DMBX1
ENSG00000197587.6 diencephalon/mesencephalon homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
DMBX1hg19_v2_chr1_+_46972668_469726690.144.6e-01Click!

Activity profile of DMBX1 motif

Sorted Z-values of DMBX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr20_+_59654146 1.48 ENST00000441660.1
RP5-827L5.1
RP5-827L5.1
chr20_+_31805131 1.41 ENST00000375454.3
ENST00000375452.3
BPIFA3
BPI fold containing family A, member 3
chr3_+_188664988 1.27 ENST00000433971.1
TPRG1
tumor protein p63 regulated 1
chr17_+_4643337 1.17 ENST00000592813.1
ZMYND15
zinc finger, MYND-type containing 15
chr17_+_4643300 1.12 ENST00000433935.1
ZMYND15
zinc finger, MYND-type containing 15
chr20_+_34556488 1.12 ENST00000373973.3
ENST00000349339.1
ENST00000538900.1
CNBD2
cyclic nucleotide binding domain containing 2
chr5_-_54988448 1.10 ENST00000503817.1
ENST00000512595.1
SLC38A9
solute carrier family 38, member 9
chr14_+_22265444 1.08 ENST00000390430.2
TRAV8-1
T cell receptor alpha variable 8-1
chr5_-_54988559 1.06 ENST00000502247.1
SLC38A9
solute carrier family 38, member 9
chr15_+_74165945 1.01 ENST00000535547.2
ENST00000300504.2
ENST00000562056.1
TBC1D21
TBC1 domain family, member 21
chr5_+_169659950 0.99 ENST00000593851.1
C5orf58
chromosome 5 open reading frame 58
chr7_-_48068671 0.98 ENST00000297325.4
SUN3
Sad1 and UNC84 domain containing 3
chr17_-_38859996 0.90 ENST00000264651.2
KRT24
keratin 24
chr18_+_5748793 0.88 ENST00000566533.1
ENST00000562452.2
RP11-945C19.1
RP11-945C19.1
chr15_-_49102781 0.80 ENST00000558591.1
CEP152
centrosomal protein 152kDa
chr2_-_27486951 0.78 ENST00000432351.1
SLC30A3
solute carrier family 30 (zinc transporter), member 3
chr17_-_4643114 0.73 ENST00000293778.6
CXCL16
chemokine (C-X-C motif) ligand 16
chr5_+_175740083 0.72 ENST00000332772.4
SIMC1
SUMO-interacting motifs containing 1
chr12_-_103310987 0.72 ENST00000307000.2
PAH
phenylalanine hydroxylase
chr14_+_22204418 0.71 ENST00000390426.2
TRAV4
T cell receptor alpha variable 4
chr7_-_142181009 0.70 ENST00000390368.2
TRBV6-5
T cell receptor beta variable 6-5
chr17_-_4643161 0.70 ENST00000574412.1
CXCL16
chemokine (C-X-C motif) ligand 16
chr16_-_31076332 0.68 ENST00000539836.3
ENST00000535577.1
ENST00000442862.2
ZNF668
zinc finger protein 668
chr15_-_61521495 0.68 ENST00000335670.6
RORA
RAR-related orphan receptor A
chr10_-_99030395 0.67 ENST00000355366.5
ENST00000371027.1
ARHGAP19
Rho GTPase activating protein 19
chr11_+_61248583 0.67 ENST00000432063.2
ENST00000338608.2
PPP1R32
protein phosphatase 1, regulatory subunit 32
chr3_-_49058479 0.59 ENST00000440857.1
DALRD3
DALR anticodon binding domain containing 3
chr3_-_48369831 0.59 ENST00000434006.1
SPINK8
serine peptidase inhibitor, Kazal type 8 (putative)
chr16_-_54304608 0.58 ENST00000561336.1
RP11-324D17.1
HCG2045435; Uncharacterized protein
chr20_-_43729750 0.58 ENST00000537075.1
ENST00000306117.1
KCNS1
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1
chr3_+_49057876 0.57 ENST00000326912.4
NDUFAF3
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr6_-_33297013 0.55 ENST00000453407.1
DAXX
death-domain associated protein
chr8_-_125577940 0.53 ENST00000519168.1
ENST00000395508.2
MTSS1
metastasis suppressor 1
chr3_+_111393659 0.50 ENST00000477665.1
PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr7_-_48068643 0.48 ENST00000453192.2
SUN3
Sad1 and UNC84 domain containing 3
chr19_-_17186229 0.47 ENST00000253669.5
ENST00000448593.2
HAUS8
HAUS augmin-like complex, subunit 8
chr2_-_165811983 0.47 ENST00000409058.1
ENST00000409149.3
SLC38A11
solute carrier family 38, member 11
chr12_-_21487829 0.46 ENST00000445053.1
ENST00000452078.1
ENST00000458504.1
ENST00000422327.1
ENST00000421294.1
SLCO1A2
solute carrier organic anion transporter family, member 1A2
chr3_+_111393501 0.45 ENST00000393934.3
PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr10_+_103986085 0.44 ENST00000370005.3
ELOVL3
ELOVL fatty acid elongase 3
chr18_-_35145728 0.44 ENST00000361795.5
ENST00000603232.1
CELF4
CUGBP, Elav-like family member 4
chr15_+_63413990 0.43 ENST00000261893.4
LACTB
lactamase, beta
chr16_-_31076273 0.43 ENST00000426488.2
ZNF668
zinc finger protein 668
chrX_-_102565932 0.42 ENST00000372674.1
ENST00000372677.3
BEX2
brain expressed X-linked 2
chr19_+_46001697 0.41 ENST00000451287.2
ENST00000324688.4
PPM1N
protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
chr15_+_63414760 0.40 ENST00000557972.1
LACTB
lactamase, beta
chr3_-_179692042 0.39 ENST00000468741.1
PEX5L
peroxisomal biogenesis factor 5-like
chr12_+_53693812 0.39 ENST00000549488.1
C12orf10
chromosome 12 open reading frame 10
chr12_-_118628315 0.38 ENST00000540561.1
TAOK3
TAO kinase 3
chr2_-_165812028 0.38 ENST00000303735.4
SLC38A11
solute carrier family 38, member 11
chr19_-_51538148 0.37 ENST00000319590.4
ENST00000250351.4
KLK12
kallikrein-related peptidase 12
chr5_+_50679506 0.35 ENST00000511384.1
ISL1
ISL LIM homeobox 1
chr1_-_28384598 0.34 ENST00000373864.1
EYA3
eyes absent homolog 3 (Drosophila)
chr5_-_92023923 0.34 ENST00000503489.1
CTC-529L17.2
CTC-529L17.2
chr11_-_45940343 0.33 ENST00000532681.1
PEX16
peroxisomal biogenesis factor 16
chr6_+_130339710 0.33 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr8_+_110656344 0.33 ENST00000499579.1
RP11-422N16.3
Uncharacterized protein
chr2_-_70780572 0.33 ENST00000450929.1
TGFA
transforming growth factor, alpha
chr2_+_37571845 0.32 ENST00000537448.1
QPCT
glutaminyl-peptide cyclotransferase
chr7_+_127116878 0.31 ENST00000448311.1
AC000124.1
AC000124.1
chr19_-_51538118 0.30 ENST00000529888.1
KLK12
kallikrein-related peptidase 12
chr1_+_120839005 0.30 ENST00000369390.3
ENST00000452190.1
FAM72B
family with sequence similarity 72, member B
chr5_+_50678921 0.30 ENST00000230658.7
ISL1
ISL LIM homeobox 1
chr2_-_70780770 0.30 ENST00000444975.1
ENST00000445399.1
ENST00000418333.2
TGFA
transforming growth factor, alpha
chr17_-_39465505 0.30 ENST00000391352.1
KRTAP16-1
keratin associated protein 16-1
chr18_-_35145593 0.30 ENST00000334919.5
ENST00000591282.1
ENST00000588597.1
CELF4
CUGBP, Elav-like family member 4
chr18_-_35145689 0.29 ENST00000591287.1
ENST00000601019.1
ENST00000601392.1
CELF4
CUGBP, Elav-like family member 4
chr18_+_29027696 0.25 ENST00000257189.4
DSG3
desmoglein 3
chr19_-_17185848 0.25 ENST00000593360.1
HAUS8
HAUS augmin-like complex, subunit 8
chrX_+_72062802 0.25 ENST00000373533.1
DMRTC1B
DMRT-like family C1B
chr1_+_206138457 0.24 ENST00000367128.3
ENST00000431655.2
FAM72A
family with sequence similarity 72, member A
chr1_+_12851545 0.24 ENST00000332296.7
PRAMEF1
PRAME family member 1
chr2_-_165811756 0.23 ENST00000409662.1
SLC38A11
solute carrier family 38, member 11
chr12_-_56321649 0.23 ENST00000454792.2
ENST00000408946.2
WIBG
within bgcn homolog (Drosophila)
chr2_+_131513158 0.22 ENST00000431758.1
AMER3
APC membrane recruitment protein 3
chr1_+_81001398 0.22 ENST00000418041.1
ENST00000443104.1
RP5-887A10.1
RP5-887A10.1
chr4_+_41937131 0.22 ENST00000504986.1
ENST00000508448.1
ENST00000513702.1
ENST00000325094.5
TMEM33
transmembrane protein 33
chr17_+_48911942 0.22 ENST00000426127.1
WFIKKN2
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr12_-_118628350 0.22 ENST00000537952.1
ENST00000537822.1
TAOK3
TAO kinase 3
chrX_-_72097698 0.22 ENST00000373530.1
DMRTC1
DMRT-like family C1
chr11_+_124055923 0.21 ENST00000318666.6
OR10D3
olfactory receptor, family 10, subfamily D, member 3 (non-functional)
chrX_+_72062617 0.21 ENST00000440247.1
DMRTC1B
DMRT-like family C1B
chr3_+_49058444 0.21 ENST00000326925.6
ENST00000395458.2
NDUFAF3
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr1_-_13452656 0.20 ENST00000376132.3
PRAMEF13
PRAME family member 13
chr1_-_247836365 0.20 ENST00000359688.2
OR13G1
olfactory receptor, family 13, subfamily G, member 1
chr14_-_23395623 0.19 ENST00000556043.1
PRMT5
protein arginine methyltransferase 5
chr7_-_142143973 0.19 ENST00000390373.2
TRBV6-7
T cell receptor beta variable 6-7 (non-functional)
chr15_+_93443419 0.19 ENST00000557381.1
ENST00000420239.2
CHD2
chromodomain helicase DNA binding protein 2
chr17_-_48207157 0.17 ENST00000330175.4
ENST00000503131.1
SAMD14
sterile alpha motif domain containing 14
chr19_+_41284121 0.16 ENST00000594800.1
ENST00000357052.2
ENST00000602173.1
RAB4B
RAB4B, member RAS oncogene family
chr2_-_220252068 0.16 ENST00000430206.1
ENST00000429013.1
DNPEP
aspartyl aminopeptidase
chr7_-_17500294 0.16 ENST00000439046.1
AC019117.2
AC019117.2
chr12_-_49581152 0.15 ENST00000550811.1
TUBA1A
tubulin, alpha 1a
chr12_+_115800817 0.14 ENST00000547948.1
RP11-116D17.1
HCG2038717; Uncharacterized protein
chr1_-_143913143 0.14 ENST00000400889.1
FAM72D
family with sequence similarity 72, member D
chr12_-_56321397 0.13 ENST00000557259.1
ENST00000549939.1
WIBG
within bgcn homolog (Drosophila)
chr3_-_19975665 0.12 ENST00000295824.9
ENST00000389256.4
EFHB
EF-hand domain family, member B
chr9_-_21994344 0.11 ENST00000530628.2
ENST00000361570.3
CDKN2A
cyclin-dependent kinase inhibitor 2A
chr21_+_18811205 0.11 ENST00000440664.1
C21orf37
chromosome 21 open reading frame 37
chr18_-_70532906 0.10 ENST00000299430.2
ENST00000397929.1
NETO1
neuropilin (NRP) and tolloid (TLL)-like 1
chr7_-_99774945 0.10 ENST00000292377.2
GPC2
glypican 2
chr9_+_74920408 0.09 ENST00000451152.1
RP11-63P12.6
RP11-63P12.6
chr4_+_619347 0.09 ENST00000255622.6
PDE6B
phosphodiesterase 6B, cGMP-specific, rod, beta
chr7_-_96132835 0.09 ENST00000356686.1
C7orf76
chromosome 7 open reading frame 76
chr9_-_21994597 0.09 ENST00000579755.1
CDKN2A
cyclin-dependent kinase inhibitor 2A
chr4_-_54232144 0.09 ENST00000388940.4
ENST00000503450.1
ENST00000401642.3
SCFD2
sec1 family domain containing 2
chrX_-_64754611 0.09 ENST00000374807.5
ENST00000374811.3
ENST00000374804.5
ENST00000312391.8
LAS1L
LAS1-like (S. cerevisiae)
chr4_+_619386 0.09 ENST00000496514.1
PDE6B
phosphodiesterase 6B, cGMP-specific, rod, beta
chr3_-_137851220 0.08 ENST00000236709.3
A4GNT
alpha-1,4-N-acetylglucosaminyltransferase
chr17_-_39324424 0.08 ENST00000391356.2
KRTAP4-3
keratin associated protein 4-3
chr2_+_73461410 0.08 ENST00000399032.2
ENST00000398422.2
ENST00000537131.1
ENST00000538797.1
CCT7
chaperonin containing TCP1, subunit 7 (eta)
chr17_+_60536002 0.07 ENST00000582809.1
TLK2
tousled-like kinase 2
chr3_+_99986036 0.07 ENST00000471098.1
TBC1D23
TBC1 domain family, member 23
chr1_+_35734562 0.06 ENST00000314607.6
ENST00000373297.2
ZMYM4
zinc finger, MYM-type 4
chr1_-_47655686 0.06 ENST00000294338.2
PDZK1IP1
PDZK1 interacting protein 1
chr14_+_22919081 0.06 ENST00000390473.1
TRDJ1
T cell receptor delta joining 1
chr12_-_10959892 0.06 ENST00000240615.2
TAS2R8
taste receptor, type 2, member 8
chr3_+_136649311 0.05 ENST00000469404.1
ENST00000467911.1
NCK1
NCK adaptor protein 1
chrX_-_48931648 0.05 ENST00000376386.3
ENST00000376390.4
PRAF2
PRA1 domain family, member 2
chr12_-_56727487 0.05 ENST00000548043.1
ENST00000425394.2
PAN2
PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr12_-_110937351 0.04 ENST00000552130.2
VPS29
vacuolar protein sorting 29 homolog (S. cerevisiae)
chr16_-_20710212 0.04 ENST00000523065.1
ACSM1
acyl-CoA synthetase medium-chain family member 1
chr6_+_10585979 0.04 ENST00000265012.4
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr19_+_36157715 0.03 ENST00000379013.2
ENST00000222275.2
UPK1A
uroplakin 1A
chr17_-_19651598 0.03 ENST00000570414.1
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr3_+_138340067 0.03 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chr2_+_73461364 0.02 ENST00000540468.1
ENST00000539919.1
ENST00000258091.5
CCT7
chaperonin containing TCP1, subunit 7 (eta)
chr12_-_76461249 0.02 ENST00000551524.1
NAP1L1
nucleosome assembly protein 1-like 1
chr2_-_14541060 0.00 ENST00000418420.1
ENST00000417751.1
LINC00276
long intergenic non-protein coding RNA 276
chr6_-_26250835 0.00 ENST00000446824.2
HIST1H3F
histone cluster 1, H3f

Network of associatons between targets according to the STRING database.

First level regulatory network of DMBX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0072738 response to diamide(GO:0072737) cellular response to diamide(GO:0072738)
0.2 0.7 GO:0048936 visceral motor neuron differentiation(GO:0021524) peripheral nervous system neuron axonogenesis(GO:0048936) cardiac cell fate determination(GO:0060913) positive regulation of granulocyte colony-stimulating factor production(GO:0071657) positive regulation of macrophage colony-stimulating factor production(GO:1901258)
0.1 0.3 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.1 0.3 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.1 0.6 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 0.8 GO:0098535 de novo centriole assembly(GO:0098535)
0.1 1.0 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.1 0.5 GO:0030035 microspike assembly(GO:0030035)
0.1 0.2 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.1 0.8 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.1 1.5 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.6 GO:1902572 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 1.4 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.7 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.4 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 2.2 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.7 GO:1902222 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0 0.4 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.0 0.6 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.2 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.3 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.6 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 0.6 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.0 GO:1903676 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.4 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.0 GO:0018874 benzoate metabolic process(GO:0018874)
0.0 2.3 GO:0007286 spermatid development(GO:0007286)
0.0 1.8 GO:0070268 cornification(GO:0070268)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 GO:0071986 Ragulator complex(GO:0071986)
0.1 0.8 GO:0098536 deuterosome(GO:0098536)
0.1 1.5 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.7 GO:0070652 HAUS complex(GO:0070652)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0015633 zinc transporting ATPase activity(GO:0015633)
0.2 0.7 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.7 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.1 1.0 GO:0042835 BRE binding(GO:0042835)
0.1 0.3 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.1 0.6 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 0.7 GO:0008142 oxysterol binding(GO:0008142)
0.0 1.5 GO:0043495 protein anchor(GO:0043495)
0.0 0.4 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.4 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 1.4 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.2 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.5 GO:0032183 SUMO binding(GO:0032183)
0.0 3.2 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.5 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 1.1 GO:0030552 cAMP binding(GO:0030552)
0.0 0.7 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 2.3 GO:0042826 histone deacetylase binding(GO:0042826)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.5 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.7 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.8 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins