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Illumina Body Map 2
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Results for DPRX
Z-value: 0.89
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Transcription factors associated with DPRX
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| DPRX | hg19_v2_chr19_+_54135310_54135310 | -0.33 | 6.8e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr18_-_64271316 Show fit | 2.83 |
ENST00000540086.1
ENST00000580157.1 |
cadherin 19, type 2 |
|
| chr18_-_64271363 Show fit | 2.43 |
ENST00000262150.2
|
cadherin 19, type 2 |
|
| chr10_-_104178857 Show fit | 1.86 |
ENST00000020673.5
|
pleckstrin and Sec7 domain containing |
|
| chr6_-_84418432 Show fit | 1.56 |
ENST00000519825.1
ENST00000523484.2 |
synaptosomal-associated protein, 91kDa |
|
| chr18_-_40857493 Show fit | 1.48 |
ENST00000255224.3
|
synaptotagmin IV |
|
| chr6_-_84418841 Show fit | 1.41 |
ENST00000369694.2
ENST00000195649.6 |
synaptosomal-associated protein, 91kDa |
|
| chr16_+_81272287 Show fit | 1.36 |
ENST00000425577.2
ENST00000564552.1 |
beta-carotene 15,15'-monooxygenase 1 |
|
| chr16_-_15950868 Show fit | 1.34 |
ENST00000396324.3
ENST00000452625.2 ENST00000576790.2 ENST00000300036.5 |
myosin, heavy chain 11, smooth muscle |
|
| chrX_+_100333709 Show fit | 1.22 |
ENST00000372930.4
|
transmembrane protein 35 |
|
| chrX_-_138724994 Show fit | 1.22 |
ENST00000536274.1
|
MCF.2 cell line derived transforming sequence |
Network of associatons between targets according to the STRING database.
First level regulatory network of DPRX
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 5.0 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.0 | 4.2 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.0 | 2.1 | GO:1990823 | response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830) |
| 0.1 | 1.7 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
| 0.5 | 1.5 | GO:0048174 | negative regulation of short-term neuronal synaptic plasticity(GO:0048174) |
| 0.2 | 1.5 | GO:2001206 | positive regulation of osteoclast development(GO:2001206) |
| 0.1 | 1.4 | GO:0045959 | regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) |
| 0.2 | 1.3 | GO:0030241 | skeletal muscle myosin thick filament assembly(GO:0030241) |
| 0.0 | 1.3 | GO:0042462 | eye photoreceptor cell development(GO:0042462) |
| 0.3 | 1.2 | GO:1990926 | short-term synaptic potentiation(GO:1990926) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 5.3 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.0 | 1.9 | GO:0032154 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.3 | 1.5 | GO:0032127 | dense core granule membrane(GO:0032127) |
| 0.0 | 1.5 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.0 | 1.3 | GO:0032982 | myosin filament(GO:0032982) |
| 0.0 | 1.3 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.2 | 1.2 | GO:0070032 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) |
| 0.0 | 1.0 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.1 | 0.9 | GO:0097179 | protease inhibitor complex(GO:0097179) |
| 0.1 | 0.9 | GO:0033269 | internode region of axon(GO:0033269) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 5.0 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.0 | 2.4 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 1.7 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.4 | 1.5 | GO:0010348 | lithium:proton antiporter activity(GO:0010348) |
| 0.1 | 1.5 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
| 0.0 | 1.5 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.0 | 1.3 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.1 | 1.2 | GO:0004705 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
| 0.0 | 1.2 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.1 | 1.1 | GO:0047498 | calcium-dependent phospholipase A2 activity(GO:0047498) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.3 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.0 | 1.6 | ST GRANULE CELL SURVIVAL PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
| 0.0 | 1.3 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.0 | 0.7 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
| 0.0 | 0.4 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.1 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.0 | 1.9 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.0 | 1.8 | REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D | Genes involved in Metabolism of steroid hormones and vitamins A and D |
| 0.0 | 1.4 | REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA | Genes involved in G beta:gamma signalling through PLC beta |
| 0.0 | 1.4 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
| 0.1 | 1.2 | REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Dopamine Neurotransmitter Release Cycle |
| 0.0 | 1.2 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.0 | 1.2 | REACTOME AMINE LIGAND BINDING RECEPTORS | Genes involved in Amine ligand-binding receptors |
| 0.1 | 1.1 | REACTOME ACYL CHAIN REMODELLING OF PS | Genes involved in Acyl chain remodelling of PS |
| 0.0 | 1.1 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |