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Illumina Body Map 2
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Results for DRGX_PROP1
Z-value: 1.01
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Transcription factors associated with DRGX_PROP1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| PROP1 | hg19_v2_chr5_-_177423243_177423243 | 0.32 | 7.3e-02 | Click! |
| DRGX | hg19_v2_chr10_-_50599907_50599907 | 0.27 | 1.4e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr15_+_48483736 Show fit | 4.23 |
ENST00000417307.2
ENST00000559641.1 |
cortexin 2 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 |
|
| chr1_+_50569575 Show fit | 3.45 |
ENST00000371827.1
|
ELAV like neuron-specific RNA binding protein 4 |
|
| chr14_+_23709555 Show fit | 3.38 |
ENST00000430154.2
|
chromosome 14 open reading frame 164 |
|
| chr14_+_62584197 Show fit | 3.22 |
ENST00000334389.4
|
long intergenic non-protein coding RNA 643 |
|
| chrX_+_107288280 Show fit | 3.03 |
ENST00000458383.1
|
V-set and immunoglobulin domain containing 1 |
|
| chr2_+_162272605 Show fit | 2.67 |
ENST00000389554.3
|
T-box, brain, 1 |
|
| chr12_-_45315625 Show fit | 2.21 |
ENST00000552993.1
|
NEL-like 2 (chicken) |
|
| chr1_+_92632542 Show fit | 2.18 |
ENST00000409154.4
ENST00000370378.4 |
KIAA1107 |
|
| chrX_+_107288197 Show fit | 2.09 |
ENST00000415430.3
|
V-set and immunoglobulin domain containing 1 |
|
| chr1_-_151148492 Show fit | 2.08 |
ENST00000295314.4
|
tropomodulin 4 (muscle) |
Network of associatons between targets according to the STRING database.
First level regulatory network of DRGX_PROP1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 7.1 | GO:0030277 | maintenance of gastrointestinal epithelium(GO:0030277) |
| 0.4 | 4.1 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
| 0.0 | 3.9 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
| 0.2 | 3.2 | GO:0043152 | induction of bacterial agglutination(GO:0043152) |
| 0.1 | 2.8 | GO:0090383 | phagosome acidification(GO:0090383) |
| 0.4 | 2.7 | GO:0021764 | amygdala development(GO:0021764) |
| 0.5 | 2.2 | GO:0060133 | somatotropin secreting cell development(GO:0060133) |
| 0.1 | 2.2 | GO:0070050 | neuron cellular homeostasis(GO:0070050) |
| 0.0 | 2.0 | GO:0035418 | protein localization to synapse(GO:0035418) |
| 0.0 | 2.0 | GO:0016266 | O-glycan processing(GO:0016266) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.1 | GO:0005865 | striated muscle thin filament(GO:0005865) |
| 0.3 | 3.9 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.1 | 2.8 | GO:0016471 | vacuolar proton-transporting V-type ATPase complex(GO:0016471) |
| 0.1 | 2.5 | GO:0033268 | node of Ranvier(GO:0033268) |
| 0.0 | 2.3 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.1 | 2.1 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.0 | 2.0 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.0 | 1.9 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.0 | 1.9 | GO:0043204 | perikaryon(GO:0043204) |
| 0.0 | 1.6 | GO:0048786 | presynaptic active zone(GO:0048786) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.4 | 4.2 | GO:0008511 | sodium:potassium:chloride symporter activity(GO:0008511) |
| 0.1 | 4.1 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.0 | 3.7 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 0.1 | 3.4 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.0 | 3.2 | GO:0051087 | chaperone binding(GO:0051087) |
| 0.3 | 2.8 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
| 0.0 | 2.3 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) |
| 0.0 | 1.9 | GO:0051393 | alpha-actinin binding(GO:0051393) |
| 0.0 | 1.9 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
| 0.2 | 1.7 | GO:0015184 | L-cystine transmembrane transporter activity(GO:0015184) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.2 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.0 | 2.0 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
| 0.0 | 1.5 | PID CD8 TCR DOWNSTREAM PATHWAY | Downstream signaling in naïve CD8+ T cells |
| 0.0 | 1.2 | PID ARF6 PATHWAY | Arf6 signaling events |
| 0.0 | 0.9 | PID IL5 PATHWAY | IL5-mediated signaling events |
| 0.0 | 0.8 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.0 | 0.8 | PID IL3 PATHWAY | IL3-mediated signaling events |
| 0.0 | 0.8 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.0 | 0.7 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.0 | 0.3 | PID GMCSF PATHWAY | GMCSF-mediated signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 3.2 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.1 | 2.8 | REACTOME INSULIN RECEPTOR RECYCLING | Genes involved in Insulin receptor recycling |
| 0.0 | 2.8 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.0 | 2.1 | REACTOME LIGAND GATED ION CHANNEL TRANSPORT | Genes involved in Ligand-gated ion channel transport |
| 0.1 | 2.0 | REACTOME AMINE DERIVED HORMONES | Genes involved in Amine-derived hormones |
| 0.0 | 2.0 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.0 | 1.7 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.0 | 1.6 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.0 | 1.5 | REACTOME ION CHANNEL TRANSPORT | Genes involved in Ion channel transport |
| 0.1 | 1.4 | REACTOME SEROTONIN RECEPTORS | Genes involved in Serotonin receptors |