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Illumina Body Map 2

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Results for DRGX_PROP1

Z-value: 1.01

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Transcription factors associated with DRGX_PROP1

Gene Symbol Gene ID Gene Info
ENSG00000165606.4 dorsal root ganglia homeobox
ENSG00000175325.2 PROP paired-like homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PROP1hg19_v2_chr5_-_177423243_1774232430.327.3e-02Click!
DRGXhg19_v2_chr10_-_50599907_505999070.271.4e-01Click!

Activity profile of DRGX_PROP1 motif

Sorted Z-values of DRGX_PROP1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_48483736 4.23 ENST00000417307.2
ENST00000559641.1
cortexin 2
solute carrier family 12 (sodium/potassium/chloride transporter), member 1
chr1_+_50569575 3.45 ENST00000371827.1
ELAV like neuron-specific RNA binding protein 4
chr14_+_23709555 3.38 ENST00000430154.2
chromosome 14 open reading frame 164
chr14_+_62584197 3.22 ENST00000334389.4
long intergenic non-protein coding RNA 643
chrX_+_107288280 3.03 ENST00000458383.1
V-set and immunoglobulin domain containing 1
chr2_+_162272605 2.67 ENST00000389554.3
T-box, brain, 1
chr12_-_45315625 2.21 ENST00000552993.1
NEL-like 2 (chicken)
chr1_+_92632542 2.18 ENST00000409154.4
ENST00000370378.4
KIAA1107
chrX_+_107288197 2.09 ENST00000415430.3
V-set and immunoglobulin domain containing 1
chr1_-_151148492 2.08 ENST00000295314.4
tropomodulin 4 (muscle)
chrX_+_107288239 2.01 ENST00000217957.5
V-set and immunoglobulin domain containing 1
chr18_+_616672 2.00 ENST00000338387.7
clusterin-like 1 (retinal)
chr1_-_151148442 2.00 ENST00000441701.1
ENST00000416280.2
tropomodulin 4 (muscle)
chr2_+_185463093 1.94 ENST00000302277.6
zinc finger protein 804A
chr5_+_96840389 1.92 ENST00000504012.1
RP11-1E3.1
chr18_+_616711 1.90 ENST00000579494.1
clusterin-like 1 (retinal)
chr6_-_107235331 1.83 ENST00000433965.1
ENST00000430094.1
RP1-60O19.1
chr14_-_75083313 1.77 ENST00000556652.1
ENST00000555313.1
CTD-2207P18.2
chr1_-_198509804 1.75 ENST00000489986.1
ENST00000367382.1
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
chr6_-_107235287 1.74 ENST00000436659.1
ENST00000428750.1
ENST00000427903.1
RP1-60O19.1
chr4_+_155484155 1.62 ENST00000509493.1
fibrinogen beta chain
chr11_+_113779704 1.62 ENST00000537778.1
5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
chr4_+_155484103 1.61 ENST00000302068.4
fibrinogen beta chain
chr5_-_160279207 1.61 ENST00000327245.5
ATPase, class V, type 10B
chr14_+_22631122 1.54 ENST00000390458.3
T cell receptor alpha variable 29/delta variable 5 (gene/pseudogene)
chr7_-_82792215 1.48 ENST00000333891.9
ENST00000423517.2
piccolo presynaptic cytomatrix protein
chr8_+_20811140 1.39 ENST00000523035.1
RP11-369E15.4
chr20_-_21086975 1.36 ENST00000420705.1
ENST00000593272.1
long intergenic non-protein coding RNA 237
chr13_-_47471155 1.35 ENST00000543956.1
ENST00000542664.1
5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
chr10_-_61900762 1.34 ENST00000355288.2
ankyrin 3, node of Ranvier (ankyrin G)
chr7_-_91794590 1.34 ENST00000430130.2
ENST00000454089.2
leucine-rich repeats and death domain containing 1
chr3_-_87325728 1.32 ENST00000350375.2
POU class 1 homeobox 1
chr6_+_78400375 1.29 ENST00000602452.2
meiosis-specific 4 homolog (S. cerevisiae)
chr13_-_45775162 1.26 ENST00000405872.1
potassium channel tetramerization domain containing 4
chr2_+_166150541 1.24 ENST00000283256.6
sodium channel, voltage-gated, type II, alpha subunit
chr3_-_9291063 1.22 ENST00000383836.3
SLIT-ROBO Rho GTPase activating protein 3
chr4_-_139051839 1.22 ENST00000514600.1
ENST00000513895.1
ENST00000512536.1
long intergenic non-protein coding RNA 616
chr4_-_103940791 1.18 ENST00000510559.1
ENST00000394789.3
ENST00000296422.7
solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1
chr14_+_22951993 1.18 ENST00000390485.1
T cell receptor alpha joining 53
chr17_+_71228793 1.17 ENST00000426147.2
chromosome 17 open reading frame 80
chr4_-_36245561 1.16 ENST00000506189.1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr4_-_176733897 1.16 ENST00000393658.2
glycoprotein M6A
chr2_-_89161064 1.15 ENST00000390241.2
immunoglobulin kappa joining 2
chr2_-_89160770 1.15 ENST00000390240.2
immunoglobulin kappa joining 3
chr6_+_15401075 1.13 ENST00000541660.1
jumonji, AT rich interactive domain 2
chr8_+_86999516 1.10 ENST00000521564.1
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr21_-_15583165 1.10 ENST00000536861.1
lipase, member I
chr4_+_48485341 1.09 ENST00000273861.4
solute carrier family 10, member 4
chr8_+_77318769 1.07 ENST00000518732.1
long intergenic non-protein coding RNA 1111
chr7_+_135710494 1.04 ENST00000440744.2
AC024084.1
chr13_-_81801115 1.03 ENST00000567258.1
long intergenic non-protein coding RNA 564
chr17_+_74463650 1.00 ENST00000392492.3
aralkylamine N-acetyltransferase
chr11_+_18433840 0.99 ENST00000541669.1
ENST00000280704.4
lactate dehydrogenase C
chr6_-_66417107 0.98 ENST00000370621.3
ENST00000370618.3
ENST00000503581.1
ENST00000393380.2
eyes shut homolog (Drosophila)
chr10_+_69865866 0.96 ENST00000354393.2
myopalladin
chr4_+_69313145 0.96 ENST00000305363.4
transmembrane protease, serine 11E
chr14_+_39944025 0.96 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
RP11-111A21.1
chr2_+_44502630 0.94 ENST00000410056.3
ENST00000409741.1
ENST00000409229.3
solute carrier family 3 (amino acid transporter heavy chain), member 1
chr6_-_41039567 0.94 ENST00000468811.1
O-acyl-ADP-ribose deacylase 1
chr3_-_3151664 0.91 ENST00000256452.3
ENST00000311981.8
ENST00000430514.2
ENST00000456302.1
interleukin 5 receptor, alpha
chr5_-_66492562 0.90 ENST00000256447.4
CD180 molecule
chr2_-_114461655 0.89 ENST00000424612.1
AC017074.2
chr2_-_89161432 0.89 ENST00000390242.2
immunoglobulin kappa joining 1
chr6_+_12007897 0.85 ENST00000437559.1
RP11-456H18.2
chr22_+_25615489 0.84 ENST00000398215.2
crystallin, beta B2
chr17_+_71228740 0.84 ENST00000268942.8
ENST00000359042.2
chromosome 17 open reading frame 80
chr3_-_87325612 0.84 ENST00000561167.1
ENST00000560656.1
ENST00000344265.3
POU class 1 homeobox 1
chr17_+_68071458 0.83 ENST00000589377.1
potassium inwardly-rectifying channel, subfamily J, member 16
chrX_+_18725758 0.82 ENST00000472826.1
ENST00000544635.1
ENST00000496075.2
protein phosphatase, EF-hand calcium binding domain 1
chr11_+_55029628 0.82 ENST00000417545.2
tripartite motif containing 48
chr5_-_54468974 0.82 ENST00000381375.2
ENST00000296733.1
ENST00000322374.6
ENST00000334206.5
ENST00000331730.3
cell division cycle 20B
chr17_+_68071389 0.82 ENST00000283936.1
ENST00000392671.1
potassium inwardly-rectifying channel, subfamily J, member 16
chr17_+_71228537 0.81 ENST00000577615.1
ENST00000585109.1
chromosome 17 open reading frame 80
chr3_-_164914640 0.81 ENST00000241274.3
SLIT and NTRK-like family, member 3
chr5_-_61031495 0.81 ENST00000506550.1
ENST00000512882.2
CTD-2170G1.2
chr2_+_44502597 0.80 ENST00000260649.6
ENST00000409387.1
solute carrier family 3 (amino acid transporter heavy chain), member 1
chr12_-_10151773 0.79 ENST00000298527.6
ENST00000348658.4
C-type lectin domain family 1, member B
chr3_-_27764190 0.79 ENST00000537516.1
eomesodermin
chr10_-_25304889 0.79 ENST00000483339.2
enkurin, TRPC channel interacting protein
chr12_+_2912363 0.78 ENST00000544366.1
FK506 binding protein 4, 59kDa
chr3_-_27763803 0.78 ENST00000449599.1
eomesodermin
chr12_+_100897130 0.77 ENST00000551379.1
ENST00000188403.7
ENST00000551184.1
nuclear receptor subfamily 1, group H, member 4
chr4_+_68424434 0.77 ENST00000265404.2
ENST00000396225.1
signal transducing adaptor family member 1
chr16_-_67517716 0.77 ENST00000290953.2
agouti related protein homolog (mouse)
chr3_+_111393501 0.76 ENST00000393934.3
phosphatidylinositol-specific phospholipase C, X domain containing 2
chrX_-_138724994 0.76 ENST00000536274.1
MCF.2 cell line derived transforming sequence
chr4_+_94125100 0.75 ENST00000512631.1
glutamate receptor, ionotropic, delta 2
chr5_-_55412774 0.75 ENST00000434982.2
ankyrin repeat domain 55
chr3_+_46395579 0.74 ENST00000421659.1
chemokine (C-C motif) receptor 2
chr5_-_11589131 0.74 ENST00000511377.1
catenin (cadherin-associated protein), delta 2
chr17_+_71228843 0.73 ENST00000582391.1
chromosome 17 open reading frame 80
chr9_+_21440440 0.73 ENST00000276927.1
interferon, alpha 1
chr6_-_40555176 0.73 ENST00000338305.6
leucine rich repeat and fibronectin type III domain containing 2
chr9_+_44867571 0.73 ENST00000377548.2
RP11-160N1.10
chr1_-_186430222 0.72 ENST00000391997.2
phosducin
chr8_-_30706608 0.71 ENST00000256246.2
testis expressed 15
chr7_-_117512264 0.70 ENST00000454375.1
cortactin binding protein 2
chr7_-_115799942 0.70 ENST00000484212.1
transcription factor EC
chr4_+_88571429 0.67 ENST00000339673.6
ENST00000282479.7
dentin matrix acidic phosphoprotein 1
chr9_+_136501478 0.66 ENST00000393056.2
ENST00000263611.2
dopamine beta-hydroxylase (dopamine beta-monooxygenase)
chr10_+_106034637 0.66 ENST00000401888.2
glutathione S-transferase omega 2
chr14_+_75536280 0.64 ENST00000238686.8
zinc finger, C2HC-type containing 1C
chr5_+_169931009 0.64 ENST00000328939.4
ENST00000390656.4
Kv channel interacting protein 1
chr6_+_88117683 0.62 ENST00000369562.4
UPF0704 protein C6orf165
chr6_-_107235378 0.61 ENST00000606430.1
RP1-60O19.1
chr8_+_67039131 0.61 ENST00000315962.4
ENST00000353317.5
tripartite motif containing 55
chr11_-_26593779 0.60 ENST00000529533.1
mucin 15, cell surface associated
chr12_+_75784850 0.60 ENST00000550916.1
ENST00000435775.1
ENST00000378689.2
ENST00000378692.3
ENST00000320460.4
ENST00000547164.1
GLI pathogenesis-related 1 like 2
chr14_+_22985251 0.58 ENST00000390510.1
T cell receptor alpha joining 27
chr5_-_111093759 0.58 ENST00000509979.1
ENST00000513100.1
ENST00000508161.1
ENST00000455559.2
neuronal regeneration related protein
chr18_-_31628558 0.57 ENST00000535384.1
nucleolar protein 4
chr1_+_149239529 0.57 ENST00000457216.2
RP11-403I13.4
chr11_-_83878041 0.55 ENST00000398299.1
discs, large homolog 2 (Drosophila)
chr12_-_65090329 0.55 ENST00000594966.1
Mesenchymal stem cell protein DSC96; Uncharacterized protein
chr8_-_57123815 0.55 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
pleiomorphic adenoma gene 1
chr16_+_81272287 0.55 ENST00000425577.2
ENST00000564552.1
beta-carotene 15,15'-monooxygenase 1
chr12_+_116985896 0.54 ENST00000547114.1
RP11-809C9.2
chr18_-_2982869 0.54 ENST00000584915.1
lipin 2
chr11_-_26588634 0.54 ENST00000436318.2
ENST00000281268.8
mucin 15, cell surface associated
chr11_-_26593677 0.54 ENST00000527569.1
mucin 15, cell surface associated
chr7_+_129847688 0.53 ENST00000297819.3
serine-rich single-pass membrane protein 1
chr1_-_247876105 0.53 ENST00000302084.2
olfactory receptor, family 6, subfamily F, member 1
chr12_+_14369524 0.53 ENST00000538329.1
RP11-134N1.2
chr11_-_26593649 0.53 ENST00000455601.2
mucin 15, cell surface associated
chr4_+_165878100 0.53 ENST00000513876.2
family with sequence similarity 218, member A
chrX_+_108779004 0.52 ENST00000218004.1
nuclear transport factor 2-like export factor 2
chr14_+_38065052 0.51 ENST00000556845.1
tetratricopeptide repeat domain 6
chr9_+_123884038 0.50 ENST00000373847.1
centriolin
chr7_+_116596704 0.50 ENST00000597499.1
ST7 overlapping transcript 4
chr12_+_122688090 0.50 ENST00000324189.4
ENST00000546192.1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
chr3_-_191000172 0.50 ENST00000427544.2
urotensin 2B
chr4_+_95916947 0.50 ENST00000506363.1
bone morphogenetic protein receptor, type IB
chr3_-_33686925 0.49 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
cytoplasmic linker associated protein 2
chr4_-_174320687 0.48 ENST00000296506.3
stimulator of chondrogenesis 1
chr7_+_123241908 0.48 ENST00000434204.1
ENST00000437535.1
ENST00000451215.1
ankyrin repeat and SOCS box containing 15
chr7_+_90338712 0.47 ENST00000265741.3
ENST00000406263.1
cyclin-dependent kinase 14
chr4_+_88754113 0.47 ENST00000560249.1
ENST00000540395.1
ENST00000511670.1
ENST00000361056.3
matrix extracellular phosphoglycoprotein
chrX_+_9935392 0.45 ENST00000445307.2
Homo sapiens uncharacterized LOC100288814 (LOC100288814), mRNA.
chr5_-_11588907 0.45 ENST00000513598.1
ENST00000503622.1
catenin (cadherin-associated protein), delta 2
chr1_-_21377383 0.45 ENST00000374935.3
eukaryotic translation initiation factor 4 gamma, 3
chr5_+_137203465 0.45 ENST00000239926.4
myotilin
chr5_-_160973649 0.45 ENST00000393959.1
ENST00000517547.1
gamma-aminobutyric acid (GABA) A receptor, beta 2
chr5_+_137203557 0.44 ENST00000515645.1
myotilin
chr1_+_174933899 0.44 ENST00000367688.3
RAB GTPase activating protein 1-like
chr3_+_111393659 0.44 ENST00000477665.1
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr18_-_19994830 0.44 ENST00000525417.1
cutaneous T-cell lymphoma-associated antigen 1
chr12_-_118797475 0.43 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAO kinase 3
chr1_+_15668240 0.43 ENST00000444385.1
forkhead-associated (FHA) phosphopeptide binding domain 1
chr12_+_72061563 0.43 ENST00000551238.1
THAP domain containing, apoptosis associated protein 2
chr1_+_158323755 0.43 ENST00000368157.1
ENST00000368156.1
ENST00000368155.3
ENST00000368154.1
ENST00000368160.3
ENST00000368161.3
CD1e molecule
chr5_-_87516448 0.42 ENST00000511218.1
transmembrane protein 161B
chr1_+_84630574 0.42 ENST00000413538.1
ENST00000417530.1
protein kinase, cAMP-dependent, catalytic, beta
chr5_+_142149955 0.41 ENST00000378004.3
Rho GTPase activating protein 26
chr17_+_44701402 0.41 ENST00000575068.1
N-ethylmaleimide-sensitive factor
chr6_-_10435032 0.41 ENST00000491317.1
ENST00000496285.1
ENST00000479822.1
ENST00000487130.1
long intergenic non-protein coding RNA 518
chr5_-_137475071 0.40 ENST00000265191.2
NME/NM23 family member 5
chr1_+_84630645 0.40 ENST00000394839.2
protein kinase, cAMP-dependent, catalytic, beta
chr6_-_24358264 0.39 ENST00000378454.3
doublecortin domain containing 2
chr9_+_20927764 0.38 ENST00000603044.1
ENST00000604254.1
focadhesin
chr4_-_46126093 0.38 ENST00000295452.4
gamma-aminobutyric acid (GABA) A receptor, gamma 1
chr4_-_184243561 0.38 ENST00000514470.1
ENST00000541814.1
claudin 24
chr12_-_57873631 0.38 ENST00000393791.3
ENST00000356411.2
ENST00000552249.1
Rho GTPase activating protein 9
chr10_+_97709725 0.37 ENST00000472454.2
Protein LOC100652732
chr10_-_128359008 0.37 ENST00000488181.1
chromosome 10 open reading frame 90
chr7_+_152456829 0.36 ENST00000377776.3
ENST00000256001.8
ENST00000397282.2
ARP3 actin-related protein 3 homolog B (yeast)
chr1_+_180199393 0.36 ENST00000263726.2
LIM homeobox 4
chr1_+_115572415 0.36 ENST00000256592.1
thyroid stimulating hormone, beta
chr17_+_44588877 0.36 ENST00000576629.1
leucine rich repeat containing 37, member A2
chr10_-_128359074 0.36 ENST00000544758.1
chromosome 10 open reading frame 90
chr5_-_111091948 0.36 ENST00000447165.2
neuronal regeneration related protein
chr5_+_140207536 0.36 ENST00000529310.1
ENST00000527624.1
protocadherin alpha 6
chr10_+_115312766 0.36 ENST00000351270.3
hyaluronan binding protein 2
chr2_+_149894968 0.35 ENST00000409642.3
LY6/PLAUR domain containing 6B
chrX_+_78200829 0.35 ENST00000544091.1
purinergic receptor P2Y, G-protein coupled, 10
chr16_-_74700737 0.35 ENST00000576652.1
ENST00000572337.1
ENST00000571750.1
ENST00000572990.1
ENST00000361070.4
ring finger and WD repeat domain 3
chr10_+_97803151 0.35 ENST00000403870.3
ENST00000265992.5
ENST00000465148.2
ENST00000534974.1
cyclin J
chr1_+_198985262 0.35 ENST00000432488.1
RP11-16L9.4
chr17_+_3118915 0.35 ENST00000304094.1
olfactory receptor, family 1, subfamily A, member 1
chr7_+_90338547 0.35 ENST00000446790.1
cyclin-dependent kinase 14
chr5_-_111312622 0.35 ENST00000395634.3
neuronal regeneration related protein
chr11_-_13517565 0.35 ENST00000282091.1
ENST00000529816.1
parathyroid hormone
chr5_+_137203541 0.34 ENST00000421631.2
myotilin
chr1_-_209957882 0.34 ENST00000294811.1
chromosome 1 open reading frame 74
chr8_-_17752996 0.33 ENST00000381841.2
ENST00000427924.1
fibrinogen-like 1
chr1_+_244214577 0.33 ENST00000358704.4
zinc finger and BTB domain containing 18
chr7_+_152456904 0.33 ENST00000537264.1
ARP3 actin-related protein 3 homolog B (yeast)
chr8_-_17752912 0.33 ENST00000398054.1
ENST00000381840.2
fibrinogen-like 1
chr7_-_115608304 0.33 ENST00000457268.1
transcription factor EC
chr2_+_149895207 0.33 ENST00000409876.1
LY6/PLAUR domain containing 6B
chr13_-_88463487 0.33 ENST00000606221.1
RP11-471M2.3
chr1_+_42846443 0.33 ENST00000410070.2
ENST00000431473.3
ribosomal modification protein rimK-like family member A
chr2_+_166430619 0.33 ENST00000409420.1
cysteine-serine-rich nuclear protein 3
chr12_-_57873329 0.33 ENST00000424809.2
Rho GTPase activating protein 9
chr17_-_38956205 0.32 ENST00000306658.7
keratin 28
chr6_+_72926145 0.32 ENST00000425662.2
ENST00000453976.2
regulating synaptic membrane exocytosis 1
chr6_+_12007963 0.32 ENST00000607445.1
RP11-456H18.2
chr12_-_118796910 0.31 ENST00000541186.1
ENST00000539872.1
TAO kinase 3
chr8_+_92114060 0.31 ENST00000518304.1
leucine rich repeat containing 69
chr22_-_30953587 0.31 ENST00000453479.1
galactose-3-O-sulfotransferase 1
chr2_+_12246664 0.31 ENST00000449986.1
AC096559.1

Network of associatons between targets according to the STRING database.

First level regulatory network of DRGX_PROP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.2 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.5 1.6 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.4 2.7 GO:0021764 amygdala development(GO:0021764)
0.4 4.1 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.3 1.0 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.3 1.0 GO:0019516 lactate oxidation(GO:0019516)
0.3 1.4 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.3 0.8 GO:1903980 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973) positive regulation of microglial cell activation(GO:1903980)
0.2 0.7 GO:2000409 astrocyte chemotaxis(GO:0035700) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265) positive regulation of T cell extravasation(GO:2000409) positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451) regulation of astrocyte chemotaxis(GO:2000458)
0.2 7.1 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.2 3.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.2 1.3 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.2 1.7 GO:0015811 L-cystine transport(GO:0015811)
0.2 1.3 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.2 0.8 GO:2000213 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.2 0.9 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.2 0.9 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.1 0.7 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1 0.7 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.1 2.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 0.4 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.1 0.3 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.1 0.5 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 0.3 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.1 0.7 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.1 0.8 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.1 0.8 GO:0097338 response to clozapine(GO:0097338)
0.1 0.1 GO:0002323 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.1 1.2 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.1 0.3 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.1 0.2 GO:0045062 extrathymic T cell selection(GO:0045062)
0.1 0.3 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.1 0.5 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 0.8 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 2.8 GO:0090383 phagosome acidification(GO:0090383)
0.1 0.3 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.1 1.2 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 0.8 GO:0009407 toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
0.1 0.2 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 1.3 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 1.6 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.4 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.7 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.3 GO:0021778 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.2 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.0 0.1 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 0.5 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.4 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.2 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.4 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.9 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.0 0.1 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.0 0.4 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.3 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 1.6 GO:0010107 potassium ion import(GO:0010107)
0.0 0.3 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.7 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.8 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.2 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.7 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 3.9 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 1.3 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 1.1 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.8 GO:0030220 platelet formation(GO:0030220)
0.0 0.7 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 2.0 GO:0035418 protein localization to synapse(GO:0035418)
0.0 0.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 2.0 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.4 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.3 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.5 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.5 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.2 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 1.1 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.7 GO:0099601 regulation of neurotransmitter receptor activity(GO:0099601)
0.0 0.4 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.5 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.5 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.2 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.3 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.8 GO:0060338 regulation of type I interferon-mediated signaling pathway(GO:0060338)
0.0 1.2 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 1.2 GO:0051453 regulation of intracellular pH(GO:0051453)
0.0 0.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.2 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 1.0 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.1 GO:0070836 caveola assembly(GO:0070836)
0.0 0.3 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0021847 ventricular zone neuroblast division(GO:0021847)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.9 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.8 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 1.4 GO:0070852 cell body fiber(GO:0070852)
0.1 2.8 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.1 4.1 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 2.5 GO:0033268 node of Ranvier(GO:0033268)
0.1 2.1 GO:0044295 axonal growth cone(GO:0044295)
0.0 1.3 GO:0000800 lateral element(GO:0000800)
0.0 0.3 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.7 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.7 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 2.0 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.2 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.5 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.4 GO:0060091 kinocilium(GO:0060091)
0.0 0.1 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 1.6 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.5 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.7 GO:0042383 sarcolemma(GO:0042383)
0.0 0.8 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.2 GO:0043194 axon initial segment(GO:0043194)
0.0 2.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.4 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 1.9 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 1.9 GO:0043204 perikaryon(GO:0043204)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.3 2.8 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2 1.0 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.2 1.7 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.2 0.8 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.2 0.9 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.2 0.7 GO:0032767 copper-dependent protein binding(GO:0032767)
0.2 1.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.7 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 0.8 GO:0050610 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.1 1.6 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.1 0.7 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 4.1 GO:0005523 tropomyosin binding(GO:0005523)
0.1 1.4 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 0.8 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 0.5 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 1.0 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.8 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 0.5 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.3 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.1 0.2 GO:0046848 hydroxyapatite binding(GO:0046848)
0.1 0.3 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590)
0.1 0.5 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.7 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1 0.3 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.1 1.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 3.4 GO:0017091 AU-rich element binding(GO:0017091)
0.1 1.5 GO:0005522 profilin binding(GO:0005522)
0.1 1.2 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.1 0.4 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.1 1.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 0.7 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 3.7 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.4 GO:0030883 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.0 1.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.5 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.7 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.3 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.1 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.0 1.2 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.8 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 1.9 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.3 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 1.9 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.7 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.7 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.4 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 1.2 GO:0032452 histone demethylase activity(GO:0032452)
0.0 1.3 GO:0030507 spectrin binding(GO:0030507)
0.0 0.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 3.2 GO:0051087 chaperone binding(GO:0051087)
0.0 0.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.8 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0 2.3 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.2 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.8 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.3 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.3 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.4 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.3 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.5 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 1.0 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.9 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.9 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.8 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.8 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.5 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 2.0 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.3 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 1.2 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.8 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 1.4 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 2.8 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 2.0 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 2.0 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 2.1 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 1.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.3 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.7 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 1.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.8 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 1.5 REACTOME ION CHANNEL TRANSPORT Genes involved in Ion channel transport
0.0 2.8 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.7 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.8 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.3 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.9 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.5 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.9 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.3 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events