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Illumina Body Map 2

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Results for E2F8

Z-value: 1.05

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Transcription factors associated with E2F8

Gene Symbol Gene ID Gene Info
E2F8
ENSG00000129173.8 E2F transcription factor 8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2F8hg19_v2_chr11_-_19263145_192631760.672.4e-05Click!

Activity profile of E2F8 motif

Sorted Z-values of E2F8 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_24346218 3.54 ENST00000436622.1
ENST00000313213.4
PFN4
profilin family, member 4
chr1_+_152850787 3.19 ENST00000368765.3
SMCP
sperm mitochondria-associated cysteine-rich protein
chr2_+_79252804 2.87 ENST00000393897.2
REG3G
regenerating islet-derived 3 gamma
chr2_-_198650037 2.84 ENST00000392296.4
BOLL
boule-like RNA-binding protein
chr13_-_19755975 2.83 ENST00000400113.3
TUBA3C
tubulin, alpha 3c
chr2_+_79252822 2.81 ENST00000272324.5
REG3G
regenerating islet-derived 3 gamma
chr2_-_152589670 2.80 ENST00000604864.1
ENST00000603639.1
NEB
nebulin
chr2_-_130956006 2.59 ENST00000312988.7
TUBA3E
tubulin, alpha 3e
chr2_+_132233664 2.39 ENST00000321253.6
TUBA3D
tubulin, alpha 3d
chr16_-_34740829 2.31 ENST00000562591.1
RP11-80F22.15
RP11-80F22.15
chr19_+_49891475 2.28 ENST00000447857.3
CCDC155
coiled-coil domain containing 155
chr2_+_79252834 2.25 ENST00000409471.1
REG3G
regenerating islet-derived 3 gamma
chr1_-_150693318 2.09 ENST00000442853.1
ENST00000368995.4
ENST00000368993.2
ENST00000361824.2
ENST00000322343.7
HORMAD1
HORMA domain containing 1
chr2_-_27362263 2.06 ENST00000432962.1
ENST00000335524.3
C2orf53
chromosome 2 open reading frame 53
chr8_+_17434689 1.97 ENST00000398074.3
PDGFRL
platelet-derived growth factor receptor-like
chr12_+_48499883 1.93 ENST00000546755.1
ENST00000549366.1
ENST00000552792.1
PFKM
phosphofructokinase, muscle
chr18_+_71983048 1.89 ENST00000579455.1
C18orf63
chromosome 18 open reading frame 63
chr22_+_19467261 1.72 ENST00000455750.1
ENST00000437685.2
ENST00000263201.1
ENST00000404724.3
CDC45
cell division cycle 45
chr9_-_7961080 1.67 ENST00000435444.1
RP11-29B9.2
RP11-29B9.2
chr10_-_131762105 1.64 ENST00000368648.3
ENST00000355311.5
EBF3
early B-cell factor 3
chr1_-_150693305 1.63 ENST00000368987.1
HORMAD1
HORMA domain containing 1
chrX_-_48216101 1.63 ENST00000298396.2
ENST00000376893.3
SSX3
synovial sarcoma, X breakpoint 3
chr19_+_41103063 1.60 ENST00000308370.7
LTBP4
latent transforming growth factor beta binding protein 4
chr6_-_166401402 1.59 ENST00000581850.1
ENST00000444465.1
LINC00473
long intergenic non-protein coding RNA 473
chr12_+_48499252 1.51 ENST00000549003.1
ENST00000550924.1
PFKM
phosphofructokinase, muscle
chr10_+_124670121 1.49 ENST00000368894.1
FAM24A
family with sequence similarity 24, member A
chr4_+_15341442 1.49 ENST00000397700.2
ENST00000295297.4
C1QTNF7
C1q and tumor necrosis factor related protein 7
chrX_-_52736211 1.43 ENST00000336777.5
ENST00000337502.5
SSX2
synovial sarcoma, X breakpoint 2
chr21_+_19273574 1.39 ENST00000400128.1
CHODL
chondrolectin
chr22_-_29457832 1.39 ENST00000216071.4
C22orf31
chromosome 22 open reading frame 31
chr2_+_74011316 1.37 ENST00000409561.1
C2orf78
chromosome 2 open reading frame 78
chr3_-_107596910 1.33 ENST00000464359.2
ENST00000464823.1
ENST00000466155.1
ENST00000473528.2
ENST00000608306.1
ENST00000488852.1
ENST00000608137.1
ENST00000608307.1
ENST00000609429.1
ENST00000601385.1
ENST00000475362.1
ENST00000600240.1
ENST00000600749.1
LINC00635
long intergenic non-protein coding RNA 635
chr15_-_89456630 1.32 ENST00000268150.8
MFGE8
milk fat globule-EGF factor 8 protein
chrX_+_105445717 1.29 ENST00000372552.1
MUM1L1
melanoma associated antigen (mutated) 1-like 1
chr15_-_89456593 1.29 ENST00000558029.1
ENST00000539437.1
ENST00000542878.1
ENST00000268151.7
ENST00000566497.1
MFGE8
milk fat globule-EGF factor 8 protein
chrX_+_52240504 1.24 ENST00000399805.2
XAGE1B
X antigen family, member 1B
chr19_+_49891533 1.23 ENST00000598730.1
ENST00000594905.1
ENST00000595828.1
ENST00000594043.1
CCDC155
coiled-coil domain containing 155
chrX_-_135338503 1.23 ENST00000370663.5
MAP7D3
MAP7 domain containing 3
chr6_-_28973037 1.23 ENST00000377179.3
ZNF311
zinc finger protein 311
chr2_-_113993020 1.22 ENST00000465084.1
PAX8
paired box 8
chr1_-_17307173 1.21 ENST00000438542.1
ENST00000375535.3
MFAP2
microfibrillar-associated protein 2
chrX_+_130192318 1.19 ENST00000370922.1
ARHGAP36
Rho GTPase activating protein 36
chr9_-_96717654 1.17 ENST00000253968.6
BARX1
BARX homeobox 1
chr19_-_35719609 1.14 ENST00000324675.3
FAM187B
family with sequence similarity 187, member B
chr10_+_118083919 1.13 ENST00000333254.3
CCDC172
coiled-coil domain containing 172
chr17_-_37123646 1.13 ENST00000378079.2
FBXO47
F-box protein 47
chr11_-_19262486 1.10 ENST00000250024.4
E2F8
E2F transcription factor 8
chrX_+_130192216 1.09 ENST00000276211.5
ARHGAP36
Rho GTPase activating protein 36
chr18_+_21718924 1.08 ENST00000399496.3
CABYR
calcium binding tyrosine-(Y)-phosphorylation regulated
chr3_-_46875313 1.08 ENST00000447340.1
PRSS42
protease, serine, 42
chr6_-_166401442 1.07 ENST00000584179.1
LINC00473
long intergenic non-protein coding RNA 473
chr2_-_177502659 1.01 ENST00000295549.4
AC017048.3
long intergenic non-protein coding RNA 1116
chr6_+_88117683 1.01 ENST00000369562.4
C6ORF165
UPF0704 protein C6orf165
chr5_-_145483932 1.00 ENST00000311450.4
PLAC8L1
PLAC8-like 1
chr11_-_110968081 1.00 ENST00000603154.1
RP11-89C3.4
RP11-89C3.4
chr9_-_74675521 1.00 ENST00000377024.3
C9orf57
chromosome 9 open reading frame 57
chr4_+_152330409 0.99 ENST00000513086.1
FAM160A1
family with sequence similarity 160, member A1
chr2_+_238395879 0.99 ENST00000445024.2
ENST00000338530.4
ENST00000409373.1
MLPH
melanophilin
chr11_-_19263145 0.98 ENST00000532666.1
ENST00000527884.1
E2F8
E2F transcription factor 8
chr8_+_106331769 0.97 ENST00000520492.1
ZFPM2
zinc finger protein, FOG family member 2
chr17_-_27949911 0.97 ENST00000492276.2
ENST00000345068.5
ENST00000584602.1
CORO6
coronin 6
chr3_+_44803322 0.97 ENST00000481166.2
KIF15
kinesin family member 15
chr12_+_3068957 0.96 ENST00000543035.1
TEAD4
TEA domain family member 4
chr3_+_127317705 0.95 ENST00000480910.1
MCM2
minichromosome maintenance complex component 2
chr4_+_128702969 0.94 ENST00000508776.1
ENST00000439123.2
HSPA4L
heat shock 70kDa protein 4-like
chrX_-_48271344 0.94 ENST00000376884.2
ENST00000396928.1
SSX4B
synovial sarcoma, X breakpoint 4B
chr4_-_152329987 0.93 ENST00000508847.1
RP11-610P16.1
RP11-610P16.1
chr4_-_141348763 0.93 ENST00000509477.1
CLGN
calmegin
chr3_+_44803209 0.92 ENST00000326047.4
KIF15
kinesin family member 15
chr6_-_57086200 0.90 ENST00000468148.1
RAB23
RAB23, member RAS oncogene family
chr11_-_107729287 0.88 ENST00000375682.4
SLC35F2
solute carrier family 35, member F2
chr12_-_8815215 0.88 ENST00000544889.1
ENST00000543369.1
MFAP5
microfibrillar associated protein 5
chr15_+_84115868 0.87 ENST00000427482.2
SH3GL3
SH3-domain GRB2-like 3
chr14_+_102027688 0.86 ENST00000510508.4
ENST00000359323.3
DIO3
deiodinase, iodothyronine, type III
chr6_-_50016364 0.85 ENST00000322246.4
DEFB112
defensin, beta 112
chr2_-_208994548 0.84 ENST00000282141.3
CRYGC
crystallin, gamma C
chr3_+_69985792 0.84 ENST00000531774.1
MITF
microphthalmia-associated transcription factor
chr12_-_8815299 0.84 ENST00000535336.1
MFAP5
microfibrillar associated protein 5
chr7_-_100026280 0.82 ENST00000360951.4
ENST00000398027.2
ENST00000324725.6
ENST00000472716.1
ZCWPW1
zinc finger, CW type with PWWP domain 1
chr7_+_75932863 0.81 ENST00000429938.1
HSPB1
heat shock 27kDa protein 1
chr14_-_67878917 0.81 ENST00000216446.4
PLEK2
pleckstrin 2
chr10_+_106028923 0.80 ENST00000338595.2
GSTO2
glutathione S-transferase omega 2
chr11_+_9595180 0.79 ENST00000450114.2
WEE1
WEE1 G2 checkpoint kinase
chr17_+_42733803 0.78 ENST00000409122.2
C17orf104
chromosome 17 open reading frame 104
chr13_+_19756173 0.78 ENST00000382988.2
RP11-408E5.4
RP11-408E5.4
chr19_+_51153045 0.77 ENST00000458538.1
C19orf81
chromosome 19 open reading frame 81
chr18_+_21719018 0.77 ENST00000585037.1
ENST00000415309.2
ENST00000399481.2
ENST00000577705.1
ENST00000327201.6
CABYR
calcium binding tyrosine-(Y)-phosphorylation regulated
chr8_+_22411931 0.77 ENST00000523402.1
SORBS3
sorbin and SH3 domain containing 3
chr17_-_15165854 0.76 ENST00000395936.1
ENST00000395938.2
PMP22
peripheral myelin protein 22
chr12_+_3069037 0.76 ENST00000397122.2
TEAD4
TEA domain family member 4
chr10_+_32856764 0.76 ENST00000375030.2
ENST00000375028.3
C10orf68
Homo sapiens coiled-coil domain containing 7 (CCDC7), transcript variant 5, mRNA.
chr3_+_44754126 0.76 ENST00000449836.1
ENST00000436624.2
ENST00000296091.4
ENST00000411443.1
ZNF502
zinc finger protein 502
chr10_+_115312766 0.75 ENST00000351270.3
HABP2
hyaluronan binding protein 2
chr9_+_124088860 0.74 ENST00000373806.1
GSN
gelsolin
chr3_-_123168551 0.73 ENST00000462833.1
ADCY5
adenylate cyclase 5
chr12_-_48499591 0.73 ENST00000551330.1
ENST00000004980.5
ENST00000339976.6
ENST00000448372.1
SENP1
SUMO1/sentrin specific peptidase 1
chr7_-_21985489 0.73 ENST00000356195.5
ENST00000447180.1
ENST00000373934.4
ENST00000457951.1
CDCA7L
cell division cycle associated 7-like
chr16_+_11439286 0.73 ENST00000312499.5
ENST00000576027.1
RMI2
RecQ mediated genome instability 2
chr14_-_61747949 0.72 ENST00000355702.2
TMEM30B
transmembrane protein 30B
chr3_-_146187088 0.72 ENST00000497985.1
PLSCR2
phospholipid scramblase 2
chr19_-_19144243 0.72 ENST00000594445.1
ENST00000452918.2
ENST00000600377.1
ENST00000337018.6
SUGP2
SURP and G patch domain containing 2
chr16_-_31147020 0.72 ENST00000568261.1
ENST00000567797.1
ENST00000317508.6
PRSS8
protease, serine, 8
chr9_-_138591341 0.71 ENST00000298466.5
ENST00000425225.1
SOHLH1
spermatogenesis and oogenesis specific basic helix-loop-helix 1
chr18_+_29078131 0.71 ENST00000585206.1
DSG2
desmoglein 2
chr3_+_14058794 0.70 ENST00000424053.1
ENST00000528067.1
ENST00000429201.1
TPRXL
tetra-peptide repeat homeobox-like
chr15_-_88247083 0.69 ENST00000560439.1
RP11-648K4.2
RP11-648K4.2
chr19_+_6740888 0.69 ENST00000596673.1
TRIP10
thyroid hormone receptor interactor 10
chr15_-_40074996 0.69 ENST00000350221.3
FSIP1
fibrous sheath interacting protein 1
chr14_-_61190754 0.69 ENST00000216513.4
SIX4
SIX homeobox 4
chr20_+_42295745 0.68 ENST00000396863.4
ENST00000217026.4
MYBL2
v-myb avian myeloblastosis viral oncogene homolog-like 2
chr14_-_55658252 0.67 ENST00000395425.2
DLGAP5
discs, large (Drosophila) homolog-associated protein 5
chr4_-_141348999 0.67 ENST00000325617.5
CLGN
calmegin
chr14_-_55658323 0.67 ENST00000554067.1
ENST00000247191.2
DLGAP5
discs, large (Drosophila) homolog-associated protein 5
chr8_-_120868078 0.67 ENST00000313655.4
DSCC1
DNA replication and sister chromatid cohesion 1
chr4_-_135248604 0.67 ENST00000515491.1
ENST00000504728.1
ENST00000506638.1
RP11-400D2.2
RP11-400D2.2
chr11_-_30105890 0.66 ENST00000527819.1
RP11-624D11.2
RP11-624D11.2
chr11_-_107729504 0.66 ENST00000265836.7
SLC35F2
solute carrier family 35, member F2
chr3_-_57113281 0.64 ENST00000468466.1
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr11_+_134201911 0.64 ENST00000389881.3
GLB1L2
galactosidase, beta 1-like 2
chr17_+_47075023 0.63 ENST00000431824.2
IGF2BP1
insulin-like growth factor 2 mRNA binding protein 1
chr17_-_15165825 0.63 ENST00000426385.3
PMP22
peripheral myelin protein 22
chr9_+_139690784 0.63 ENST00000338005.6
KIAA1984
coiled-coil domain containing 183
chr16_-_31146961 0.62 ENST00000567531.1
PRSS8
protease, serine, 8
chr3_+_127317066 0.62 ENST00000265056.7
MCM2
minichromosome maintenance complex component 2
chr19_-_49828438 0.61 ENST00000454748.3
ENST00000598828.1
ENST00000335875.4
SLC6A16
solute carrier family 6, member 16
chr11_-_71639613 0.61 ENST00000528184.1
ENST00000528511.2
RP11-849H4.2
Putative short transient receptor potential channel 2-like protein
chr11_-_83435965 0.61 ENST00000434967.1
ENST00000530800.1
DLG2
discs, large homolog 2 (Drosophila)
chr22_+_24105241 0.61 ENST00000402217.3
C22orf15
chromosome 22 open reading frame 15
chr8_+_27632083 0.60 ENST00000519637.1
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr3_+_140770183 0.60 ENST00000310546.2
SPSB4
splA/ryanodine receptor domain and SOCS box containing 4
chr17_+_39975455 0.60 ENST00000455106.1
FKBP10
FK506 binding protein 10, 65 kDa
chr14_+_24837226 0.59 ENST00000554050.1
ENST00000554903.1
ENST00000554779.1
ENST00000250373.4
ENST00000553708.1
NFATC4
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
chr4_-_141348789 0.59 ENST00000414773.1
CLGN
calmegin
chr6_+_160693591 0.59 ENST00000419196.1
RP1-276N6.2
RP1-276N6.2
chr1_-_146989697 0.58 ENST00000437831.1
LINC00624
long intergenic non-protein coding RNA 624
chr9_-_23821273 0.58 ENST00000380110.4
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chr17_-_39928106 0.58 ENST00000540235.1
JUP
junction plakoglobin
chr3_-_25824925 0.57 ENST00000396649.3
ENST00000428257.1
ENST00000280700.5
NGLY1
N-glycanase 1
chr10_-_46167722 0.57 ENST00000374366.3
ENST00000344646.5
ZFAND4
zinc finger, AN1-type domain 4
chr10_-_17659234 0.56 ENST00000466335.1
PTPLA
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr1_-_36916011 0.56 ENST00000356637.5
ENST00000354267.3
ENST00000235532.5
OSCP1
organic solute carrier partner 1
chr6_+_135502466 0.56 ENST00000367814.4
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr4_+_55096489 0.55 ENST00000504461.1
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr1_+_43637996 0.55 ENST00000528956.1
ENST00000529956.1
WDR65
WD repeat domain 65
chr19_-_17559376 0.55 ENST00000341130.5
TMEM221
transmembrane protein 221
chr17_+_7184986 0.54 ENST00000317370.8
ENST00000571308.1
SLC2A4
solute carrier family 2 (facilitated glucose transporter), member 4
chr12_-_102455846 0.54 ENST00000545679.1
CCDC53
coiled-coil domain containing 53
chr12_-_102455902 0.54 ENST00000240079.6
CCDC53
coiled-coil domain containing 53
chr1_-_32827682 0.54 ENST00000432622.1
FAM229A
family with sequence similarity 229, member A
chr17_+_42733730 0.54 ENST00000359945.3
ENST00000425535.1
C17orf104
chromosome 17 open reading frame 104
chr17_-_56769382 0.53 ENST00000240361.8
ENST00000349033.5
ENST00000389934.3
TEX14
testis expressed 14
chr1_-_27709816 0.53 ENST00000374030.1
CD164L2
CD164 sialomucin-like 2
chr10_-_17659357 0.53 ENST00000326961.6
ENST00000361271.3
PTPLA
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr19_-_56704421 0.52 ENST00000358992.3
ZSCAN5B
zinc finger and SCAN domain containing 5B
chr17_+_39975544 0.52 ENST00000544340.1
FKBP10
FK506 binding protein 10, 65 kDa
chr18_-_19994830 0.52 ENST00000525417.1
CTAGE1
cutaneous T-cell lymphoma-associated antigen 1
chrX_+_24073048 0.52 ENST00000423068.1
EIF2S3
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
chr14_-_23624511 0.51 ENST00000529705.2
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr3_-_185542761 0.50 ENST00000457616.2
ENST00000346192.3
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr19_+_12203100 0.50 ENST00000596883.1
ZNF788
zinc finger family member 788
chrX_-_130423386 0.50 ENST00000370903.3
IGSF1
immunoglobulin superfamily, member 1
chr1_-_36916066 0.49 ENST00000315643.9
OSCP1
organic solute carrier partner 1
chr6_+_24357131 0.49 ENST00000274766.1
KAAG1
kidney associated antigen 1
chr19_+_12203069 0.49 ENST00000430298.2
ENST00000339302.4
ZNF788
ZNF788
zinc finger family member 788
Zinc finger protein 788
chr3_-_151176497 0.48 ENST00000282466.3
IGSF10
immunoglobulin superfamily, member 10
chr12_+_75760714 0.48 ENST00000547144.1
GLIPR1L1
GLI pathogenesis-related 1 like 1
chr3_-_79816965 0.48 ENST00000464233.1
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr10_+_35416223 0.47 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
CREM
cAMP responsive element modulator
chr1_+_33283246 0.47 ENST00000526230.1
ENST00000531256.1
ENST00000482212.1
S100PBP
S100P binding protein
chr12_-_66275350 0.47 ENST00000536648.1
RP11-366L20.2
Uncharacterized protein
chr12_-_6798025 0.47 ENST00000542351.1
ENST00000538829.1
ZNF384
zinc finger protein 384
chr19_-_47291843 0.46 ENST00000542575.2
SLC1A5
solute carrier family 1 (neutral amino acid transporter), member 5
chr11_+_101981423 0.46 ENST00000531439.1
YAP1
Yes-associated protein 1
chr11_+_125496124 0.45 ENST00000533778.2
ENST00000534070.1
CHEK1
checkpoint kinase 1
chr1_-_158656488 0.45 ENST00000368147.4
SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr1_+_33283043 0.44 ENST00000373476.1
ENST00000373475.5
ENST00000529027.1
ENST00000398243.3
S100PBP
S100P binding protein
chr17_-_46623441 0.43 ENST00000330070.4
HOXB2
homeobox B2
chr11_-_73882249 0.42 ENST00000535954.1
C2CD3
C2 calcium-dependent domain containing 3
chr17_+_46125707 0.41 ENST00000584137.1
ENST00000362042.3
ENST00000585291.1
ENST00000357480.5
NFE2L1
nuclear factor, erythroid 2-like 1
chr6_-_84937314 0.41 ENST00000257766.4
ENST00000403245.3
KIAA1009
KIAA1009
chr22_+_40742512 0.41 ENST00000454266.2
ENST00000342312.6
ADSL
adenylosuccinate lyase
chr17_+_46125685 0.41 ENST00000579889.1
NFE2L1
nuclear factor, erythroid 2-like 1
chr7_-_21985656 0.40 ENST00000406877.3
CDCA7L
cell division cycle associated 7-like
chr2_-_37193606 0.40 ENST00000379213.2
ENST00000263918.4
STRN
striatin, calmodulin binding protein
chr7_+_128379449 0.40 ENST00000479257.1
CALU
calumenin
chr1_-_55230165 0.40 ENST00000371279.3
PARS2
prolyl-tRNA synthetase 2, mitochondrial (putative)
chr3_-_185542817 0.40 ENST00000382199.2
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr1_-_27709793 0.40 ENST00000374027.3
ENST00000374025.3
CD164L2
CD164 sialomucin-like 2
chr10_+_35416090 0.39 ENST00000354759.3
CREM
cAMP responsive element modulator
chr6_+_117002339 0.39 ENST00000413340.1
ENST00000368564.1
ENST00000356348.1
KPNA5
karyopherin alpha 5 (importin alpha 6)
chr6_-_2962331 0.39 ENST00000380524.1
SERPINB6
serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr7_+_128379346 0.39 ENST00000535011.2
ENST00000542996.2
ENST00000535623.1
ENST00000538546.1
ENST00000249364.4
ENST00000449187.2
CALU
calumenin
chr2_-_230787879 0.38 ENST00000435716.1
TRIP12
thyroid hormone receptor interactor 12
chr17_+_46126135 0.38 ENST00000361665.3
ENST00000585062.1
NFE2L1
nuclear factor, erythroid 2-like 1
chr2_+_233385173 0.38 ENST00000449534.2
PRSS56
protease, serine, 56
chr22_+_40742497 0.38 ENST00000216194.7
ADSL
adenylosuccinate lyase
chr15_+_40731920 0.38 ENST00000561234.1
BAHD1
bromo adjacent homology domain containing 1
chr18_-_12656715 0.37 ENST00000462226.1
ENST00000497844.2
ENST00000309836.5
ENST00000453447.2
SPIRE1
spire-type actin nucleation factor 1
chr17_-_9479128 0.37 ENST00000574431.1
STX8
syntaxin 8
chr14_+_36295504 0.37 ENST00000216807.7
BRMS1L
breast cancer metastasis-suppressor 1-like

Network of associatons between targets according to the STRING database.

First level regulatory network of E2F8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.9 GO:0044278 cell wall disruption in other organism(GO:0044278)
1.2 3.7 GO:0060629 regulation of homologous chromosome segregation(GO:0060629)
0.7 2.1 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.6 3.4 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.6 1.7 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.6 2.8 GO:0007525 somatic muscle development(GO:0007525)
0.4 1.2 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.4 3.2 GO:0007341 penetration of zona pellucida(GO:0007341)
0.3 4.3 GO:0042989 sequestering of actin monomers(GO:0042989)
0.3 1.1 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.2 1.0 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.2 1.3 GO:0034421 post-translational protein acetylation(GO:0034421)
0.2 0.8 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.2 1.3 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.2 0.5 GO:1904897 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.2 0.7 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.2 0.2 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.2 0.8 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.2 0.5 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827) negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.2 4.0 GO:0090220 chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220)
0.2 2.0 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 2.6 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 0.4 GO:0021569 rhombomere 3 development(GO:0021569)
0.1 0.7 GO:0003165 Purkinje myocyte development(GO:0003165)
0.1 0.7 GO:0021823 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.1 1.2 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.1 0.4 GO:0006433 prolyl-tRNA aminoacylation(GO:0006433)
0.1 0.6 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.1 0.5 GO:1903803 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.1 0.7 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.1 0.8 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.1 0.3 GO:0060796 regulation of transcription involved in primary germ layer cell fate commitment(GO:0060796)
0.1 2.8 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 0.8 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.1 0.3 GO:0018012 N-terminal peptidyl-alanine methylation(GO:0018011) N-terminal peptidyl-alanine trimethylation(GO:0018012) N-terminal peptidyl-glycine methylation(GO:0018013) N-terminal peptidyl-proline dimethylation(GO:0018016) peptidyl-alanine modification(GO:0018194) N-terminal peptidyl-proline methylation(GO:0035568) N-terminal peptidyl-serine methylation(GO:0035570) N-terminal peptidyl-serine dimethylation(GO:0035572) N-terminal peptidyl-serine trimethylation(GO:0035573)
0.1 0.6 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.1 2.0 GO:0035791 platelet-derived growth factor receptor-beta signaling pathway(GO:0035791)
0.1 0.2 GO:0072737 response to diamide(GO:0072737) cellular response to diamide(GO:0072738)
0.1 1.3 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.1 0.9 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.1 0.3 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1 0.5 GO:0032466 negative regulation of cytokinesis(GO:0032466)
0.1 0.3 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.1 2.1 GO:0003351 epithelial cilium movement(GO:0003351)
0.1 0.3 GO:0061358 negative regulation of Wnt protein secretion(GO:0061358)
0.1 0.8 GO:0090487 toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
0.1 0.3 GO:2000521 negative regulation of immunological synapse formation(GO:2000521)
0.1 0.2 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.1 0.6 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.3 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.1 0.2 GO:1904117 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.1 0.5 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 0.4 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.3 GO:0021997 neural plate axis specification(GO:0021997)
0.0 1.4 GO:0032060 bleb assembly(GO:0032060)
0.0 0.4 GO:0040038 polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649)
0.0 0.7 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.1 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.3 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.1 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
0.0 2.2 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.3 GO:1902731 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.0 1.7 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.3 GO:0046826 negative regulation of protein export from nucleus(GO:0046826) protein K6-linked ubiquitination(GO:0085020)
0.0 1.7 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.9 GO:0048368 lateral mesoderm development(GO:0048368)
0.0 0.4 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.7 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.2 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.2 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.9 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 1.7 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.2 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 1.7 GO:0035329 hippo signaling(GO:0035329)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.4 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 1.2 GO:0048536 spleen development(GO:0048536)
0.0 0.1 GO:1903566 ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
0.0 0.2 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.4 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.6 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 1.3 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 0.4 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.6 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 1.0 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.5 GO:0000732 strand displacement(GO:0000732)
0.0 0.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 1.8 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.1 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.6 GO:0046710 GDP metabolic process(GO:0046710)
0.0 0.2 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.2 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.2 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.2 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.2 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.7 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.0 1.1 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.0 GO:0006481 C-terminal protein methylation(GO:0006481)
0.0 0.4 GO:0019054 modulation by virus of host process(GO:0019054)
0.0 0.8 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.5 GO:1901998 toxin transport(GO:1901998)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.5 1.9 GO:0005873 plus-end kinesin complex(GO:0005873)
0.4 3.4 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.3 3.5 GO:0072687 meiotic spindle(GO:0072687)
0.2 0.9 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.2 0.7 GO:0031523 Myb complex(GO:0031523)
0.1 0.6 GO:0071665 gamma-catenin-TCF7L2 complex(GO:0071665)
0.1 1.9 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 0.8 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 2.9 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 1.8 GO:0042555 MCM complex(GO:0042555)
0.1 0.3 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.1 3.9 GO:0000795 synaptonemal complex(GO:0000795)
0.1 0.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.2 GO:0033186 CAF-1 complex(GO:0033186)
0.1 1.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 0.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.7 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.1 0.4 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.7 GO:0030478 actin cap(GO:0030478)
0.0 0.8 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 1.1 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.1 GO:1990423 RZZ complex(GO:1990423)
0.0 1.4 GO:0043218 compact myelin(GO:0043218)
0.0 0.6 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 2.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.4 GO:0032437 cuticular plate(GO:0032437)
0.0 0.7 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.3 GO:0070847 core mediator complex(GO:0070847)
0.0 0.4 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.6 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.7 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.8 GO:0030057 desmosome(GO:0030057)
0.0 0.3 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 1.1 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.2 GO:0033503 HULC complex(GO:0033503)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.5 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.6 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.9 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.2 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.3 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 2.8 GO:0030018 Z disc(GO:0030018)
0.0 0.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.1 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:0005019 platelet-derived growth factor beta-receptor activity(GO:0005019)
0.4 7.9 GO:0042834 peptidoglycan binding(GO:0042834)
0.3 3.4 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.2 0.8 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.2 0.8 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor alpha-receptor activity(GO:0005018)
0.2 0.6 GO:0000224 peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity(GO:0000224)
0.2 1.2 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.2 2.6 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.6 GO:0005199 structural constituent of cell wall(GO:0005199)
0.1 0.8 GO:0016672 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.1 0.4 GO:0004827 proline-tRNA ligase activity(GO:0004827)
0.1 2.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.7 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 0.9 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 2.8 GO:0008494 translation activator activity(GO:0008494)
0.1 1.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.8 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 0.7 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 0.3 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.1 0.7 GO:0045159 myosin II binding(GO:0045159)
0.1 0.5 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 1.9 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.1 3.5 GO:0070840 dynein complex binding(GO:0070840)
0.1 0.3 GO:0038047 beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
0.1 0.3 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.1 0.5 GO:0034711 inhibin binding(GO:0034711)
0.1 0.2 GO:0030395 lactose binding(GO:0030395)
0.1 0.5 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 0.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 3.5 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.2 GO:0003896 DNA primase activity(GO:0003896)
0.1 0.4 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 0.2 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.1 0.5 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.2 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.0 0.6 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.4 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.5 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 2.2 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.9 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.5 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.2 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.0 0.5 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.7 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 1.3 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.6 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 1.1 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.6 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.2 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.3 GO:0019863 IgE binding(GO:0019863)
0.0 2.8 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 6.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.2 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.5 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.8 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.2 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 1.4 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.4 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.3 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 0.3 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.2 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.8 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.3 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 7.0 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.0 GO:0090541 MIT domain binding(GO:0090541)
0.0 1.3 GO:0017022 myosin binding(GO:0017022)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 2.0 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.4 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.3 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.1 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.2 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.5 GO:0070888 E-box binding(GO:0070888)
0.0 0.6 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 1.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.0 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.0 0.3 GO:0043495 protein anchor(GO:0043495)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 2.5 PID ATR PATHWAY ATR signaling pathway
0.0 9.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.7 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 2.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 2.6 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.8 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.4 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.0 PID AURORA A PATHWAY Aurora A signaling
0.0 2.4 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.5 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.8 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.9 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.6 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 5.2 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 1.5 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 0.9 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 3.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 2.6 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.9 REACTOME KINESINS Genes involved in Kinesins
0.0 2.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.8 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.7 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.7 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.9 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.7 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 1.1 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.7 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.8 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 1.1 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)